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AZERBAIJAN MEDICAL UNIVERSITY
PHARMACEUTICAL FACULTYEDUCATIONAL PROGRAM
(I – IV courses)
____ / ____ educ. years
1
I course
Thematic plan of lectures on general chemistry (autumn semester)
№ Subject hours1. The chemistry as a science. Chemistry as a science of nature
and its relation to other sciences. The role of chemistry in medicine and pharmacology. The thermo- chemistry. The modern representations of solutions. The water as a universal solvent. The electrolytic dissociation. The degree and constant of dissociation. The ionic product of water and pH – the basic or acidic characteristic of medium.
2
2. Atom is the basis of material world. The planetary or nuclear model of an atom. The characteristic of an atomic energy levels by quantum numbers. Electronic formulas.
2
3. The periodic law of Mendeleev. The periodic system of elements from the point of view of atomic structure. The redox reactions. The main oxidizing and reducing agents. Types of redox reactions, balancing of redox reactions. The influence of medium on redox reactions.
2
4. The classical and contemporary representations of the nature of chemical bonds. The types of chemical bonds.
2
5. Covalent bond, the formation mechanism of covalent bond. The shape of electron clouds and their overlapping. σ and π –bonds. The hybridisation of orbitals and shape of molecules.
2
6. Complex compounds. The coordination theory of Verner. The nature of coordinative bonds. Contemporary theories of complex compounds (VB, TCF, TMO).
2
7. The classification, izomerization, nomenclature of complex compounds. The role of complex compounds in living organism, chelates.
2
Total hours 14
2
Thematic plan of practical tranig on general chemistry (autumn semester)
№ Subject hours 1. The basic conceptions and laws of chemistry. Solving of
problems. The equivalent in chemical reactions. The law of equivalent. Solving of problems.
4
2. Concentration of solutions, method of expression. Laboratory work. Preparation of solutions of various concentration and transition from one concentration to another.
4
3. Solving of problems to concentration of solutions. Survey of material. The water as a universal solvent.
4
4. The electrolytic dissociation. Strong and weak electrolytes. The degree and constant of dissociation. Solving of problems.
4
5. Hydrolysis. The product of solubility. Solving of problems. 4
6. Thermochemistry. Hess law and its consequences. Solving of problems.
4
7. The redox reactions, types: intermolecular, intramolecular, disproportion. Two methods of formulation of equations redox reactions. The factors affecting the redox reactions. Exercises.
4
8. Atomic structure. The periodic law of Mendeleev and an explanation of the system. Classification of chemical elements from the point of view of modern atomic structure: s-elements, p-elements, d- elements, f-elements.
4
9. Description of the energy levels of electrons in atoms by quantum numbers. Exercises on electron formulas of atoms.
4
10. Chemical bonds and molecules structure. Hybridization of atomic orbitals.
4
11. Saturation and direction of covalent bond. Hydrogen bonds and its role in living organism.
4
12. Other types of chemical bonds. Metallic, three-electron, dative, localized, delocalized bonds.
4
13. Complex compounds, its nomenclature and isomerisation. 4
14. The modern theory of complex compounds (VB, MO, CF). 4
15. Biological complexes and its role in living organism.Internal complexes.
4
16. The final laboratory work. 1
Total hours 61
3
Thematic plan of lectures and practical trainingon inorganic chemistry (spring semester)
№ Subject hours
1. s-Elements, their position in the periodic system. Hydrogen. Organogenic and biogenic s-elements. Elements of IA, IIA. P-Elements. Elements of IIIA group.
2
2. The general characteristic of the elements of IV-VA groups, their chemical properties and role in medicine.
2
3. The general characteristic of the elements of VIA and VIIA groups. Preparation and properties of their basic compounds. 2
4. The general characteristic of d-elements. The elements of III-V B groups.
2
5. The general characteristic of the VI-VII B groups elements. Preparation and properties of their basic compounds. 2
6. The general characteristic of VII B group elements. İron, cobalt, nickel. Biological complexes of iron and cobalt, their role in medicine.
2
7. The general characteristic of the I-II B groups elements. Preparation and properties of their basic compounds, role in the life organism.
2
Total hours 14Thematic plan of lectures and practical training
on inorganic chemistry (spring semester)
№ Subject hours
1. Hydrogen, its basic compounds and properties. Elements of IA groups, properties of compounds. Laboratory work: experiments on alkali metals. Elements of II A group, their general characteristic. Biological role.
4
2. Laboratory work: on s2 elements and chemical properties of its basic compounds. Chemistry of IIIA group elements. Boron and aluminium.
4
3. Laboratory work: on preparation and properties of basic compounds of boron and aluminium. Chemistry of IV A group elements. Carbon and silicon.
4
4. Laboratory work: on preparation and properties of compounds of carbon and silicon. Survey. Chemistry of VA group elements. Nitrogen, phosphorus, arsenic.
4
5. Laboratory work: on preparation and properties of nitrogen’s
4
compounds. Laboratory work: on preparation and properties of phosphorus compounds.
4
6. Laboratory work: on preparation and properties of oxygen.Laboratory work: on preparation and properties of sulphur, hydrogen sulphide, sulphides and oxides of sulphur.
4
7. Chemistry of VIIA group elements. Laboratory work: on preparation and properties of halogens and their basic compounds. Survey.
4
8. The elements of VI B group, their general characteristic.Chemistry of chrome and molybdenum. Laboratory work: on preparation and properties of basic compounds of Cr and Mo.
4
9. Chemistry of manganese. Laboratory work: on preparation and properties of basic compounds of manganese.
2
10 Chemistry of iron, cobalt and nickel. Laboratory work: on preparation and properties of basic compounds of iron and cobalt.
2
11. Chemistry of I B group elements. Chemistry of copper, gold, silver.
2
12. Laboratory work: on preparation and properties of basic compounds of copper.
2
13. Laboratory work: on preparation and properties of basic compounds of silver.
2
14. Chemistry of II B group elements. Laboratory work: on preparation and properties of basic compounds of zinc.
2
15. Laboratory work: on preparation and properties of basic compounds of mercury.
2
Total hours 46
Thematic plan on «History of Pharmacy and Deontology»
Lectures (autumn term)1 General information regarding pharmacy and pharmaceutical
sciences. Ancient drug dosage forms and its originating. History of ancient drugs formulations.
2
2 History of development of world pharmacy in the period of MiddleAges
2
3 History of development of new and contemporary world pharmacy 24 History of development of national pharmacy in the Middle Ages 25 Development history of National Pharmacy inSoviet Time 26 History of development of national Pharmacy in the modern period 27 Pharmaceutical bioethics.The Convention of Europe Councilabout
bioethics. The foundation of pharmaceutical ethics and bioethics.2
8 Bioethics, pharmaceutical ethics and deontology. Aspects of pharmaceutical bioethical relations.
2
9 Clinical trials of drugs: bioethical aspects of pre-and post-clinical 2
5
trials Total hours 18
Thematic plan Practice on «History of Pharmacy and Deontology»
1 Original information about drug formulations and pharmaceutical sciences. History of originating of ancient drugs. History of ancient medicines preparations.
2
2 History of development of world pharmacy in the Middle Ages 43 History of National pharmacy development in the Middle Ages 44 History of National pharmacy development in Soviet Time. 25 History of National pharmacy development in the time of
Independence2
6 General information about pharmaceutical deontology. Bioethical committees. Pharmaceutical ethics committees. Convention of the Council of Europe about bioethics
2
7 Foundations of pharmaceutical ethics and bioethics. General problems of bioethics in the sphere of Pharmaceutical Care and pharmaceutical marketing
4
8 Bioethics, pharmaceutical ethics and deontology. Some aspects of pharmaceutical bioethics: relations of pharmacist-pharmacist, pharmacist-doctor, pharmacist-patient. Bioethical problems in the sphere of relations “Pharmacist- manufacturer”
2
9 Clinical trials of drugs: bioethical aspects pre-and post-clinical trials 3
Total hours 25The plan of lectures on history of Azerbaijan
N Themes Hours1 Primitive society and tehmost ancient states on the area of
Azerbaijan2
2 Azerbaijan in the period of feudalism 2
3 Azerbaijan in the structure of Arabian Caliphate 2
4 The feodal states in the Azerbaijan in IX-XII centuries 2
5 Azerbaijan in XIII-XIV centuries 2
6 Azerbaijan feodal states in the XV century 2
7 Sefevids` state 2
8 Azerbaijan in XVIII ceuntury 2
9 The conquest of the Northern Azerbaijan by Russia 2
10 Azerbaijan in the period of capitalism 2
6
11 Azerbaijan in the period beginning of XX century 2
12 Azerbaijan People Society 2
13 The Northern Azerbaijan in the structure of the Soviet Empire 2
14 Azerbaijan in the period before and after of world war II (1930-1970)
2
15 Azerbaijan on the way to independence 2
Total hours 30The plan of practical training on history of Azerbaijan
N Themes Hours1 Primitive society and tehmost ancient states on the area of
Azerbaijan4
2 Azerbaijan in the period of feudalism 4
3 Azerbaijan in the structure of Arabian Caliphate 4
4 The feodal states in the Azerbaijan in IX-XII centuries 4
5 Azerbaijan in XIII-XIV centuries 4
6 Azerbaijan feodal states in the XV century 4
7 Sefevids` state 4
8 Azerbaijan in XVIII ceuntury 4
9 The conquest of the Northern Azerbaijan by Russia 4
10 Azerbaijan in the period of capitalism 4
11 Azerbaijan in the period beginning of XX century 4
12 Azerbaijan People Society 4
13 The Northern Azerbaijan in the structure of the Soviet Empire 4
14 Azerbaijan in the period before and after of world war II (1930-1970)
4
15 Azerbaijan on the way to independence 4
Total hours 60The plan of lectures on right basis
N Themes Hours1 The concept of “medical rights”. History, subject and method 22 The bases of the theory of the state and rights. The bases of
constitutional right2
3 The law of the Azerbaijan Republic on public health care 24 The principles of public health care: rendering free medical 2
7
services in combination with paid medical activity5 Reproductive human rights as subsective constitutional law. Legal
questions of transplantation 2
6 The bases of labor legal relationship in medical activity 27 The bases of criminal law. Crimes committed in the sphere of
health care and the methods for their prevention 2
8 The bases of family and property rigths 29 The crimes connected with illicit trafficing in drugs and
psychotropic substances2
10 Legal bases of medical insurance 211 The problems of protection of the patient`s rights 212 Ecological problems of environmental protection during the
modern period. Legal responsibility for ecological offenses2
13 The law of the Azerbaijan Repablic on sanitary and epidemiologic improvement
2
14 Legal bases on pharmacentical activity 215 The law of the Azerbaijan Republic on fight against corruption and
criminal liability in connection with corruption2
Total hours 30The plan of lectures on economic theory
N Themes Hours1 G.Aliev – Heydar Aliyev is founder of the national economy.
Economic theory and its role for modern development of the community. Economic theory subject and method
2
2 History of economic thought in Azerbaijan 23 Economic system. Property relations. Privatization – related
matters2
4 Production, its factors and reproduction 25 Goods production and money 26 Market and market economics. Demand and suggestion.
Competition and monopoly. National economics and national market
2
7 Scientific-technical progress and scientific-technical revolution. Improvement of material-technical basis of health
2
8 Agricultural relations. Basic directions of agricultural reforms hold within Azerbaijan
2
9 Unemployment and employment. Demography policy 210 Formation and distribution of population`s profits. Standart of
living2
11 Financial relation. Budget and tax systems. Credit system and banks. Financing of health
2
12 Firm (enterprise) and its activity mechanism. Management, enterpreneurship. Management of health
2
8
13 Global economic issues. Ecology and well-being of human. Ecology and economics
2
14 Azerbaijan in the world economics integration 215 World economics and international market. International trade.
Exchange relationships2
Total hours 30The plan of seminar on economic theory
N Themes Hours1 G.Aliev – Heydar Aliyev is founder of the national economy.
Economic theory and its role for modern development of the community. Economic theory subject and method
2
2 History of economic thought in Azerbaijan 23 Economic system. Property relations. Privatization – related
matters2
4 Production, its factors and reproduction 25 Goods production and money 26 Market and market economics. Demand and suggestion.
Competition and monopoly. National economics and national market
2
7 Scientific-technical progress and scientific-technical revolution. Improvement of material-technical basis of health
2
8 Agricultural relations. Basic directions of agricultural reforms hold within Azerbaijan
2
9 Unemployment and employment. Demography policy 210 Formation and distribution of population`s profits. Standart of
living2
11 Financial relation. Budget and tax systems. Credit system and banks. Financing of health
2
12 Firm (enterprise) and its activity mechanism. Management, enterpreneurship. Management of health
2
13 Global economic issues. Ecology and well-being of human. Ecology and economics
2
14 Azerbaijan in the world economics integration 215 World economics and international market. International trade.
Exchange relationships2
Total hours 30
The plan of lectures on “Normal Physiology (spring term)
N Themes Hours1 Physiology is science about the dynamics of whole organism.
General common peculiarities of living organisms. Self-2
9
regulation principles. General structural principles and architectonics of functional systems. General properties of excited tissues. Bioelectrical phenomenon. Resting potential and action potential. Rules of excitation. Morphophysiological characteristics of muscles. Mechanism of muscle contraction. Types of contraction. Muscle fatigue. Physiological characteristics of smooth muscles
2 Significance of blood circulation for organism. Methods of research of the heart activity. Phases of heart beat. Physiological characteristics of cardiac muscle. Stroke volume of the heart and cardiac output. External manifestations of heart activity. Neurohumoral and reflex regulations of heart activity.
2
3 Basic principles of hemodynamics. Rate of blood flow, its determination, arterial pressure, pulse. Vasomotor centers. Regulation of vascular center. Dynamic mechanism of functional system regulating normal blood pressure which will provide optimal metabolism.
2
4 Significance of respiration. Mechanism of inspiration and expiration. Pneumothorax. Transport of gases in the blood. Respiratory center. Neuro-humoral regulation of respiration. Breathing under different atmospheric pressures. Types of hypoxia. Composition of functional systems maintaining the normal level of oxygen and carbon dioxide in the organism
2
5 Significance of digestion. Digestion in the oral cavity and in the stomach. Phases of gastric juice secretion. Mechanism of evacuation of the food from stomach into duodenum. Digestion in duodenum, small and large intestines. Functions of liver. Mechanism of bile formation and its role in digestion. Mechanism of absorption. Physiological bases of hunger and thirsty. Content and architectonics of functional system maintaining the normal level of nutritional substances in the blood.
2
6 Significance of excretory system. Mechanism of urine formation. Amount and content of urine. Neuro-humoral regulation of renal activity. Mechanism of urine excretion. Endocrine secretion of pancreas, thyroid, adrenal, pituitary glands, and thymus. Pineal and sexual glands.
2
7 Morphophysiological peculiarities of nerve system. Peculiarities of transmission of excitation in nerve fibers. Parabiosis. Pessimal inhibition. Classification of synapses. Central nervous System. Main principles of development of reflex theory from Dekart to Anokhin). Peculiarities of nerve centers. Inhibition in the Central Nervous System. Coordination of reflex processes. Convergence and occlusion. Irradiation of excitation in Central Nervous System. Methods of research of the
2
10
CNS activity. Resiprocal inhibition. Ascending and descending effects of Reticular formation. Subcortical nuclei. Physiology of Cerebellum. Physiology of spinal cord, medulla oblongata, mesencephalon and diencephalon.
8 General and specific peculiarities of receptors. Sense of smell. Sense of taste. Sense of hearing. The vision. Pain problem and its mechanism.Localization of functions in the cerebral cortex. Unconditioned and conditioned reflexes, their classification. Elaboration of conditioned reflexes. Inhibition in the cerebral cortex. The first and the second signaling systems.Types of Higher Nervous Activity.Sleep and hypnosis. Physiology of motivation, emotion and behavior. Psychical and labor activity of man, and functional system providing it.
2
Total hours 16
The plan of laboratory studies on “Normal Physiology” (spring term)
N Themes Hours1 Purpose of physiological experiment and its organization.
Neuro-muscular physiology. Making of neuro-muscular preparation, methods of irritation. Recording of muscle solitary contraction. Effect of temperature, power and frequency of stimulation on a muscle solitary contraction. Muscle work, power and fatigue. Ergography. Bioelectric phenomenon in excitable tissues. Galvani’s experiments. Laws of transmission of excitation. Polar rule of Excitation. Law of physiological electrotonus
2
2 Content, Amount, and Physical-chemical peculiarities of blood.Buffer properties of blood. Hemolysis and its types. Determination of osmotic resistance of erythrocytes. Counting of RBC, WBC and thrombocytes. Determination of hemoglobin content in the blood. Determination of blood groups. Rhesus factor. Determination of Erythrocyte Sedimentation Rate by Panchenkov method. Determination of blood clotting time.
2
3 Physiological properties of heart muscle. Graphic recording of heart activity in frog. Stimulation of cardiac muscle by electrical current. Cardiac automatism (Stannius ligatures). ECG. Heart sounds. Regulation of heart activity (nervous, humoral and reflex). Effect of vagosympathetic bundle on heart activity of a frog. Effect of adrenaline and acetylcholine on heart activity (Schtraub experiment). Effect of stimulation of reflexogenic zones on heart activity (Holtz and Aschner-Danini reflexes)
2
11
4 Physiology of vessel system. Observation of blood circulation in web membrane of a frog.Nervous regulation of the vascular tone (Walter and Claude-Bernard experiments). Measuring of arterial pressure in human. Arterial and venous pulse.
2
5 Independent work. Solving the tests and situational tasks on “Excitable tissues”, “Blood”, “Blood circulation”.Concluding session.
2
6 Functions and general properties of hormones. Effect of adrenaline and acetylcholine on frog eye pupil. Influence of insulin on the blood sugar level
2
7 Respiration. Mechanism of inspiration and expiration. Scheme of action of the ribs, Donders model. Pneumography, spyrometry. Determination of minute respiratory volume of lungs.
2
8 Digestion. Observation of salivary secretion in dog. Observation of salivary secretion in rabbit under influence of cholinepotentiated substances. Observation of gastric juice secretion in dog. Analyses of gastric juice. Observation of isolated small intestine contractions (Magnus experiment).The study of role of liver in carbohydrate metabolism at devisceration condition, observation of absorption in acute experiment (Heidenhain experiment)
2
9 The study of excretory system and endocrine glands activity in experiments. Observation of urine excretion in acute experiments. The study of inhibitory action of pituitrin on urine excretion. Effect of adrenaline and acetylcholine on frog eye pupil.Influence of insulin on the blood sugar of mice.
2
10 Independent work. Solving the tests and situational tasks on “Endocrine glands”, “Respiration”, “Digestion”.Concluding session.
2
11 Central nervous system. Observation of spinal cord reflexes. Analysis of reflex arc. Determination of reflex time. Irradiation of excitation in spinal cord. Inhibition in Central Nervous System. Sechenov inhibition. Effect of chemical substances on the excitability of Central Nervous System.
2
12 Higher Nervous Activity. Elaboration of conditioned nutritional reflexes. Observation of conditioned defense reflexes.
2
13 Elaboration of self-stimulation reaction observed during the electrical stimulation of dorso-lateral nuclei of hypothalamus in rabbit. Elaboration of alimentary behavior during the stimulation of ventro-lateral nuclei of hypothalamus in rabbit.
2
14 Study of functions of analyzes. Determination of tactile sensitivity threshold (law of Veber-Fechner). Determination of
2
12
visual and hearing acuity. Determination of gustatory sense
15 Independent work. Solving the tests and situational tasks on” CNS”, “Higher Nervous Activity” and “Analyzers”.
3
Total hours 31
The plan of lectures on medical and biological physics
(spring term)
№ Themes Hours1 Subject of medical and biological physics. Periodical mechanical
processes in living organisms. Harmonic oscillations. Energy of harmonic oscillation. Addition of oscillations. Damped oscillations. Forced oscillations. Self-induced oscillations. Complex vibration. Harmonic spectrum of complex vibration. Mechanical wave. Equation of wave. Doppler's effect and its use in medicine.
2
2 Acoustics. Nature and physical properties of sound. Audiometry. Physical bases of sound methods in clinics. Wave resistance. Use of ultrasound in medicine.
2
3 A strength and potential of electric field.The electric dipole. Electric field of dipole. A dipole in an electric field. Energy of electric field. A multipole. Electric dipole generator (current dipole). Physical bases of electrocardiography. Vectorcardiography.
2
4 Magnetic interaction of currents. Biot-Savart's law. Intensity of magnetic field of current. Intensity of magnetic fields due to circular and direct currents. Total current relationship. An intensity of magnetic field of solenoid.Current carrying loop in a magnetic field.
2
5 Interference of light. Coherency. Interference in thin films. Use of interference. Interferometers and their use in medicine. Concept of the interference microscope. Diffraction of light. Huygens-Fresnel's principle. Diffraction of parallel rays. Diffraction grating. Holography and its application in medicine.
2
6 X-rays. Bases of roentgenestructural analysis. Stopping and characteristic X-rays. Mutual interaction between X-rays and substance. Physical bases of use of X- rays in medicine. X-ray structure analysis and it's use in medicine. Radioactivity. Principal law of radioactive decay. Activity. Mutual interaction of ionizing rays with matter. Biophysical bases of action of ionizing rays on organism. Bases of dosemetry . Use of radionuclides and neutrons in medicine. Radiation and expose dose. Equivalent dose.
2
7 Energy radiation and absorption in atoms and molecules. Spontaneous and induced radiations. Ruby laser. Helium-Neon Laser. Properties of laser radiation. Use of lasers in medicine.
2
Total hours 1413
The plan of practical training on medical and biological physics(spring term)
№ Themes Hours1 The role of physics in medicine. Errors in measurements of physical
quantities and their calculation. Distribution and explanation of laboratory works.
2
2 Determination of parameters of harmonic motion by spring pendulum. 23 Determination of coefficient of internal friction in real liquids by
Ostvald's and Hess viscosimeters.2
4 Measurement of coefficient of internal friction in real liquids by Stock's method.
2
5 Measurement of surface tension in liquids by drop method. Physical bases of blood pressure measurement.
2
6 Determination of specific weight of liquids and solids by pycnometer. 27 Study of operational principle galvanization apparatus and measurement
of power in treatment circuit.2
8 Study the apparatus of UHF (ultrahigh frequency) and measurement its vibration frequency. Operation of UHF apparatus.
2
9 Study of alternating current circuit. Measurement of inductance and inductive resistance.
2
10 Graduating thermocoule and thermistor. Measuring temperature. 211 Measurement of light wavelength by diffraction grating. 212 Measurement of concentration of sugar solution by polarimeter. 213 Determination of magnification of microscope. Measurement of index of
refraction in liquids by refractometer.2
14 Measuring concentration of solution by colorimeter. 2Problem Solving
15 Mechanical oscillations and waves. 216 Acoustics. 217 Liquid’s flow and mechanical properties of biological tissnes. 218 Control work on mechanics. 219 Electric field. 220 Magnetic field. 221 Alternating current. Electromagtenic oscillations and waves. 222 Control work on electromagnetism. 223 Geometrical optics and quantum property of light. 224 Interfernce of light. 225 Difraction of light. 226 Polarization of light. Thermal radiation of bodies. 227 Thermal radiation of bodies. 228 Interaction of light and matter. X-ray radiation. 2
14
29 Radiiactivity and Dosimetry. 230 Final lesson 2
Total hours 60
The plan of lectures on “High mathematics”
№ Themes Hours1 Principles of the theory of probability. Random events. The statistic
and classical definitions of probability. Theorems for addition and multiplication of probabilities.
2
2 The discrete and continuous random quantities. Distribution function of discrete random quantity. Characteristics of distribution.
2
3 Continuous random quantities. Distribution function, its density. Laws of equal and normal distributions. Probability of finding of continuous random quantity in the given interval.
2
4 Problem of mathematical statistics. Principal and selected collections. Variation series, polygon and histogram.
2
5 Estimation the characteristics of distribution. Rheability range for the estimation of the mathematical expectation. Student`s distribution.
2
Total hours 10
The plan of practical training on “High mathematics”
№ Themes Hours1 Basic elementary functions, their domains and ranges. 22 Limit of a function. Continuous functions. Rules for limit
calculations.2
3 Outstanding limits and examples to them. 24 Comparison of infinitesmall functions by limit 25 First order derivative of a function. Examples. 26 Geometrical and mechanical meaning of derivative. 27 Calculation the derivatives of complex and unknown functions. 28 Rules for calculations of high order derivatives. 29 Examples of search of functions by derivative. 210 Problems of search of functions by differential. 211 Control work N 1. 212 Calculation of partial and total differentials for multi variable
functions.2
13 Antiderivative and examples to indefinite integral. 214 Substitution rule for the evaluation of the indefinite integrals. 215 Example solution on the integration by parts. 2
15
16 Example solutions on the definite integrals. 217 Use of definite integrals in problems of physics, chemistry and
biology.2
18 Ordinary differential equations. Partial and common solutions. 219 Differential equations in problems of physics, chemistry and
biology.2
20 Control work N 2. 221 Probability of random events. Addition and multiplication of
probabilities.2
22 Problems on computation of numerical characteristics for the discrete random quantities.
2
23 Principal and selected collections. Variation series. Drawing the polygon and histograms.
2
24 Student`s distribution, its use in error computations. 225 Control work N 3. 2
Total hours 30
Latin language I-term (autumn)
№ The main themes of the practical classes Hour
1 Introduction, alphabet.Short and long syllables
2 2
2 Stress, exercises.Verbs. Imperative mood.
2 2
3 The verb “esse” and the auxiliary verb “fiere” Information about nouns First declination of nouns
2
2 4 Uncoordinated attribute. Nouns with
Greek origin II declination of nouns. Masculine gender.
2
2 5 II declination of nouns. Neuter gender.
Peculiarities of neuter gender. 2 2
6 Information about adjectives. I group adjectivesCoordinated attribute
2 2
7 Chemical nomenclature Names of acids
2 2
8 Greek numerals in chemical nomenclature and names of carbohydrogenies
2
16
9 III declination of nouns. Common information
2 2
10 III declination, masculine gender 2
11 III declination, feminine gender 2
12 III declination, neuter genders. 2
13 Nomenclatura of medicinal means.
I, II, III ture qoroups 2
14 Nomenclatura of medicinal means.IV, V ture groups. Vitamins and hormones/
2
15 15 weeks total studies 1
Grand total : 29
The plan of practical training on Informatics and computer
№ Mövzular Saat
1 Information. Information types, amont of information and information coding. Notations. Transition from rules from one notation into another. Units of measure of information amount
2
2 Test 1 (Information). Device and architecture of a computer. Technical characteristics of a computer 2
3
Software. System programs (operating systems, drivers, utilities). Applied programs (test editor, spreadsheets, databases, etc.). Operating systems. WINDOWS. Office programsof the Window operating system. Elements of a window and their appointment (line of heading, system menu line, toolbar, address line, working area, scrolling strip, condition line). Desktop and its elements. Main and context menus of system. Work with files and folders. Program conductor
2
4
Test 2 (Computer devices). Text editor WORD. Main Window of WORD. The menu line (File, Edit, View, Insert, Format, Tools, Table, Window, Help). The toolbar line. Work with texts (creation and saving of text documents, text input, editing, formatting of texts)
2
5 Tables in WORD, graphic possibilities of Word. Work with tables. Printing of documents. 2
6 EXCEL spreadsheet. Creation and filling of tables. Input and 2
17
editing of functions. Main Excel functions and their application. Creation of charts in Excel, editing and formatting. Creation lists. Streamlining of data, filters. Application of Excel spreadsheet
7 The decision in Excel of tasks with linear, branching and cyclic algorithms. 2
8 The decision in Excel of tasks with enclosed cycles 29 Creation of charts. Test 3 (Excel) 210 Presentation program MS Power Point 2
11Computer networks. Internet. Work bases on Internet. Protocols. Addressing in Internet. E-mail. Receiving and parcel of messages by e-mail
2
12 Test 4 (Internet). Use of information resources on Internet. Loading of files from the Internet. Information search systems 2
Total hours 24
The plan of lectures on Human Anatomy 1
N Themes Hours1 The general anatomy of skeleton. The structure of bones. The
growth of bone, the influence of external factors to bone growth. The functional anatomy of joints. The classification and development of joints. The structure of simple synovial joint. The skull, the vertebral column, the thoracic cage and pelvis
2
2 The morpho-functional anatomy of the muscles. A muscle as an organ. The structure of muscles. The force and work of muscle. The functional classification of muscles
2
3 The general information about the splanchnology. The functional anatomy of internal organs. The functional anatomy of digestive organs
2
4 The functional anatomy of organs of the respiratory system. The functional anatomy of urogenital organs
2
5 The nervous system. The structural elements of nervous system: spinal cord and brain. The spinal nerves
2
6 The functional anatomy of sensory organs. The cranial nerves. The autonomic nervous system
2
7 The cardiovascular system. The functional anatomy of heart. The systemic, pulmonary circuits and microcirculation. The structural features of lymphatic system
2
Total hours 14
The plan of practical training on Human Anatomy 1
N Themes Hours1 The structure, functional anatomy and joints of bones of the trunk 2
18
2 The structure, functional anatomy and joints of bones of the extremities
2
3 The skull bones: structure, features, topography and joints 2
4 The functional anatomy of muscles of the head and neck 2
5 The functional anatomy of muscles of the extremities 2
6 The organs of digestive system: structure and functional anatomy 2
7 The organs of respiratory system: structure and functional anatomy 2
8 The urogenital organs: structure and functional anatomy. The endocrine organs: structure and functional anatomy
2
9 The nervous system: structure, elements. The spinal cord. The spinal nerves, plexuses and their branches. Brain: parts, structure. The cerebral vesicles and their derivates
2
10 The sensory organs, functional anatomy. The cranial nerves 2
11 The cardiovascular system. The blood circuits and their functional features
2
12 The heart: structure and topography. The blood supply and innervation of the heart
2
13 The aorta: parts, branches. The blood supply of the organs, extremities and brain
2
14 The venous system. The superior and inferior venae cavae. The portal vein
2
15 The lymphatic system. The autonomic nervous system 2
The plan of practical training on English language
(spring term)№ Mövzular Saat
1. Azerbaijan Medical UniversityWord order. Affirmative sentences. General questions 2
2. Medical student’s working dayConjunctions, Addition and Contrast, Reason, Purpose, Result, Condition
2
3. Medical EducationSpecial, Alternative, Disjunctive Questions 2
4. A student’s viewThe Preposition. Space, Time 2
5. Our ProfessionThe Verb Be; There + Be 2
6. Choosing a specialtyHave and have got; Do Regular and Irregular verbs 2
7. Hippocrates – the father of medicine 2
19
Modal Verbs: Can/Could and be able to8. Artists studying the human body
Must and have to; May and Might; Should 2
9. The duties of a doctorThe Imperative sentences 2
10. Assisted dyingPronouns 2
11. Health Care in AzerbaijanNoun; Noun Suffixes; Singular and Plural Nouns. Possessive Case of Nouns
2
12. World Health Organization (WHO)Adjective; Adjective Suffixes. Degrees of Comparison of the Adjective
2
13. Progress Test 214. Lifestyle and Health
Tense Category. Simple Tenses 2
15. Health and DietAdverbs: Frequency and Degrees 2
16. Inheritance and HealthPresent Simple 2
17. How genetic disorders are inherited 218. Maintaining Body Weight
Past Simple “Used to do” 2
19. Symptoms and signsFuture Simple “I will” and “I am going to“ 2
20. Are symptoms and signs useful information in diagnosing? 221. Progress Test 222. Viral Infections
Participle I 2
23. Infections - the most common cause of diseases 224. Scarlet Fever
Participle II 2
25. ChickenpoxVerb + Infinitive 2
26. MeaslesVerb + -ing Forms (I like doing) 2
27. Childhood Infectious diseases 228. Septicaemia 229. Septicaemia infection of people with reduced immunity 230. Progress Test 231. The Human Body
Continuous Tenses 2
32. Systems of BodyPresent Continuous 2
20
33. Ears, Hearing and BalancePresent Continuous and Present Simple 2
34. Ears – provider of two vital senses 235. Eyes and Vision. The Structure of the Eyes
Past Continuous 2
36. The Teeth. Protection of the teeth 237. Skeleton
Future Continuous 2
38. Main parts of the skeleton 239. Study of human body by Renaissance artists 240. Lungs
Perfect Tenses 2
41. The Structure of The LungsPresent Perfect 2
42. The Function of The Lungs 243. Breathing and Respirations
Past Perfect 2
44. Physiology of Respiration 245. Progress test 246. Structure of the Heart 247. Systemic and pulmonary circuits 248. Heart Valves
Perfect Tenses 2
49. The Heart CycleAdjective forming suffixes: -al; -ar; -ful 2
50. Main phases of the heartbeat 251. Blood
Past participle (Participle II)2
52. Progress Test 253. Liver, Stomach, Gallbladder and Pancreas 254. The Abdomen 255. Location of the liver. Functions of the liver
Present Participle and its functions 2
56. Location of pancreas and gallbladder. Functions of pancreas 257. Gastric and Duodenal Ulcers
Complex Subject 2
58. Chronic Gastritis 259. Prevention of Gastrointestinal Disorders 260. Progress Test 261. Brain, Spinal Cord and Nerves 2
21
62. Sensory Receptors 263. The Kidneys 264. Urine Excretion 265. Hormones and metabolism
The Complex Sentence 2
66. FracturesPassive Voice 2
67. Nasal PolypsSimple Passive 2
68. Pneumonia 269. Atherosclerosis
Modals + Passive 2
70. Indigestion. Food PoisoningThe Simple Sentence. The Compound Sentence 2
71. Anxiety Disorders. Stress ControlThe Complex Sentence 2
72. AnaemiaThe Complex Sentence. Object Clause 2
73. AllergiesThe Complex Sentence. Attribute Clause 2
74. Acquired ImmunodeficiencyThe Complex Sentence. Adverbial Clause 2
75. Progress Test 2Cəmi: 150
saat
II course
Thematic plan of lectures on organic chemistry (autumn semester)
№ Topic hours 1. Classification of organic compounds. Chemical bonds in
organic molecules. The mechanism of organic reactions.2
2. Structure of organic compounds. Stereoisomers. Configuration Conformation. Analysis of organic compounds. Analysis of organic compounds.
2
3. Hydrocarbons. Alkanes, cycloalkanes. Alkenes, alkadienes, alkynes. Arenes.
2
22
4. Mono- and polifunctional compounds.Halogen derivatives ofhydrocarbons. Nitrogen-organic compounds. Alcohols and phenols. Aldehydes and ketones.
2
5. Organic acids. Ethers and esters. 26. Heterofunctional compounds. Aminoalcohols and
aminophenols. Oxyacids. 2
7. Oxyacids and oxoacids. 2Total hours 14
Thematic plan of practical trainig on organic chemistry (autumn semester)
№ Topic hours
1 Rules in the laboratory of organic chemistry. Safety equipment. Chemical vessels and equipment.
4
2 Interference of atoms in organic molecules. Chemical bonds. Electron effects. Acidity and basicity in organic compounds. Simple and fractional distillation
4
3 Stereoisomers. Configurations and conformation. Enantiomers and diastereomers. Spectroscopy.
Determination of the radiation coefficient and the melting point.4
4 Control work. Tests. 45 Hydrocarbons. Alkanes, cycloalkanes. Alkenes, alkadienes
and alkynes. Arenes. Preparation of ethylene and acetylene. Qualitative reactions on double and triple bonds.
4
6 Halogen derivatives of hydrocarbons. Alcohols and phenols. Qualitative determination of amines and halides.
4
7 Nitrogen-organic compounds. Aldehydes and ketones. 48 Control work. Tests. 49 Monobasic saturated and unsaturated acids. Synthesis of
benzoic acid.4
10 Dibasic saturated and unsaturated acids. Ethers and esters. Preparation of ethyl ether.
4
11 Control work. Tests. 412 Heterofunctional compounds. Aminoalcohols and
aminophenols. Qualitative reactions of aminoalcohols. 4
13 Oxy- and phenol acids. Qualitative determination of functional groups in salicylic acid.
4
14 Oxoacids. 415 Control work. Tests. 5
Total hours 61
23
Thematic plan of lectures on organic chemistry (spring semester)
№ Topic hours
1. Five- and six-membered heterocyclic compounds. 22. Condensed heterocyclic compounds. 23. Alkaloids. 24. Aminoacids, peptides and proteins. 25. Carbohydrates. 26. Nucleic acids. 27. Lipids. 2
Total hours 14
Thematic plan of practical training on organic chemistry (spring semester)
№ Topic hours 1. Five-membered heterocyclic compounds. 42. Six-membered heterocyclic compounds. 43. Condensed heterocyclic compounds. 44. Control work №1. Heterocyclic compounds. 45. Aminoacids. 46. Peptides and proteins. 47. Control work №2. Amino acids, peptides and proteins. 48. Monosaccharides. 49. Di- and polysaccharides. 4
10. Nucleic acids. 4 11. Control work №3. Carbohydrates. Nucleic acids. 4 12. Undergoing to hydrolysis lipids. 4 13. Not undergoing to hydrolysis lipids. 4 14. Alkaloids. 4 15. Control work №4. Lipids. Alkaloids. 5
Total hours 61
Thematic plan of lectures on analytical
chemistry (autumn semester)
№ Topic hours
24
1.The subject of analytical chemistry, the goal, aims. Chemical analysis, classification. Qualitative analysis, classification. 2
2. The specificity and sensitivity of analytical reactions.The theory of activity, ionic strength. Law of mass action, value.
2
3. Protolytic theory. Ionic product of solubility. Calculation of pH acids and bases.
2
4. Solvolysis reactions and buffer systems. 2
5. The solubility product, the influence of various factors on the solubility.
2
6. The analytical value of oxidation-reduction reactions. 27. Complex compounds and their analytical value. 28. Extraction method and its analytical value. 29. Methods of chromatography. 2
Total hours 18
Thematic plan of practical training on analytical chemistry (autumn semester)
№ Topic hours 1.1. The rule of work and safety in chemical laboratory. First aid
cases. Chemical reagents. Analytical reactions and techniques of conducting. Qualitative analysis, classification.
Reactions in solution. Dry reaction. Pyrochemical reaction. Systematic and individual analysis.
6
2.2. Acid-base classification of cations. Reactions of cations of Ianalytical group. Analysis of analytical mixture of cations I group. Free work: carrying out the reactions of I analytical group of cations.
6
3.3. The reactions of cations of II analytical group. Free work: an analysis of a mixture of cations of I analytical group.
Solving of problem: Analytical sensitivity of the reaction.6
4.4. Analysis of mixture of cations of the II analytical group. Free work: carrying out of the reactions of the cations of II analytical group. Solving of problem: the calculation of the activity and ionic strength.
6
5.5. The reactions of the cations of the III analytical group. Free wook: carrying out of the analysis of a mixture of cations of II analytical group. Solving of problem: the calculation of ion activity and ionic strength.
6
6. Analysis of a mixture of cations of the III analytical group. Free work: conducting of analytical reactions of cations of III group. Solving of problem: about the solubility product.
6
7. Reactions of cations of IV analytical group. Free work:
25
an analysis of a mixture of cations of the III analytical group. Solving of problem: the calculation of solubility and the influencevarious factors.
4
8. Survey of material (cations of I-III analytical groups.)The analysis of mixtures of cations IV analytical group. Free work: the reactions of cations of IV analytical group.
4
9. The reactions of the cations of V analytical group. Free work:an analysis of a mixture of cations of IV analytical group.Solving of problem: the calculation of the pH of various electrolytes, ionization constants, the degree of ionization.
4
10. The analysis of mixtures of cations of V analytical group. Free work: carrying out of the reactions of cations of V analytical group. Solving of problems: the calculation of constant of hydrolysis, degree of hydrolysis and pH of salts undergoing hydrolysis.
4
11. The reactions of cations of VI analytical group. Free wook: an analysis of a mixture of cations of V analytical group.
Solving of problems: the calculation of the pH buffer solutions and buffer capacity.
4
12. The analysis of mixtures of cations of VI analytical group. Freework: carrying out of the reactions of cations of VI analitical group. Solving of problem: about the equilibrium constant for oxidation-reduction reactions and the possibility of proving the reaction.
4
13. The reactions of anions of I and II groups. Free work: an analysis of a mixture of cations of VI group. Survey of material (IV-VI groups of cations).
4
14. The reactions of anions of III group. The analysis of cations by extraction and chromatography. Free work: conducting of the reactions of anions of I and II groups.
4
15. Methods of qualitative chromatography, principles. The mobileand the stationary phase. Paper chromatography, species. Thin-layer chromatography, species. The developing reagent. The concept of Rf. Precipitation chromatography. Separation of cations by chromatography. Survey of material.
4
Total hours 72
Thematic plan of lectures on analytical chemistry (spring semester)
№ Topic hours 1. Quantitative analysis, basic principles, classification. Titrimetriya,
classification, types of titration. The acidbase titration, curves, the error. 2
2. Redox-metry, the error, curves. Precipitation titration, the error, curves. 2
26
Complexometry, errors. 3. Methods of instrumental analysis, classification. Optical methods.
Molecular-absorption methods. Colorimetry. 2
4. Photocolorimeters. Photometric determination. Spectrophotometry. 25. Photometric reactions. Extraction-photometric analysis. Fluorescence. 26. Method of electrochemical analysis. Potentiometry. Conductivemetry. 27. Coulometry. Polarography. 2
Total hours 14
Thematic plan of laboratory studieson analytical chemistry (spring semester)
№ Topic hours
1. Quantitative analysis. Gravimetric analysis. Analytical balance and weights. Determination of water of crystallization of barium hloride. Self work: the definition of water of crystallization of barium chloride.
4
2. Determination of iron and sulfate. Self work: Determination of iron.
4
3. Determination of moisture and ash in medicines. Self work: finish the work started. Solving of problem: calculations in gravimetric analysis.
4
4. Titrimetric analysis, meaning, measuring instruments and vessels. Self work: refinement of capacity measuring vessels.
4
5. Calculations in titrimetric analysis. Calculation of correction factor.
4
6. Acid-base titration. Preparation and standardization of standard solutions. Self work: preparation and standardizetion of 0.1 mol/l hydrochloric acid, oxalic acid, sodium hydroxide solutions.
4
7. Method of acidimetric titration. Self work: analysis of carbonates. Analysis of the mixture of carbonates and hidrocarbonates, analysis of the mixture of alkaline and carbonates.
4
8. Method of alkalimetric titration. Self work: Determination of hydrochloric acid, acetic essence, acetylsalicylic acid (aspirin) and salicylic acid. Titration in non-aqueous medium. Determination of potassium acetate.
4
9. Method of permanganometric titration. Self work:Preparation and standardization of the standard solutions.Analysis of solution of hydrogen peroxide and iron alum.
4
10.
Method of iodometric titration. Self work: preparation and standardization of the standard solution. Determination of arsenic anhydride, ascorbic acid and iodine. Solving of problems: on method.
4
27
11.
Method of iodometric titration. Self work: analysis of formaldehyde, hydrogen peroxide, copper (II) sulfate, potassium permanganate.
4
12.
Bromatometry, chromatometry, cerimetry and nitritometry titrations. Self work: preparation and standardization of the standard solution. Definition of arsenic anhydride, phenol, resorcinol, salicylic acid, iron (II) sulfate, procaine (novocain), sulfanilamide (streptocid), sodium nitrite, etc.
4
13.
Method of precipitation titration (argentometry, rodanometry, Merkuro-metry). Self work: preparation and standardization standard solution. Determination of halogens and silver salts.
4
14.
Complexometric titration method. Self work: preparation and standardization of standard solution. Analysis zinc sulfate.Determination of calcium and magnesium ions. Determination of water hardness.
4
15.
Method of quantitative chromatography. Paper chromatography and chromatography on a thinlayer of sorbent. Gas and ion exchange chromatography.
4
16.
Result. 1
Total hours 61
Thematic plan of lectures on physical chemistry (autumn semester)
№ Topic hours 1 The subject of physical chemistry, its content, aim,
main stages of development , application in medicine. Thermodynamics, its kinds, “0”, I laws. Chemical thermodynamics as theoretical fundament of bioenergy
2
2
The II, III law of thermodynamics. Entropy, its calculation for various processes. Entropy and thermodynamic probability. Thermodynamic potentials. Gibbs energy and biological systems.
2
3 Thermodynamics of chemical equilibrium. Law of interac tion of masses. Isothermal, isochoric, isobaric equations of chemical reaction. Equilibrium phases. Gibbs phases rule. Phase diagram for the one component system. Clapeyron- Clausius equation.
2
4 Solutions. Modern representation about mechanism of solubility. Thermodynamics of formation of solutions. Dissolution of gasses in liquids and blood. Henry Dalton law. İdeal and real solutions. Cryoscopy and
2
28
ebulioscopy. Raoult's and Van’t Hoff laws. Conovalov’s laws.
5 The theory of electrolitic dissociation. Dissosiation degree and dissosiation constant. Ionic product of water. pH as hydrogen index. Activity and ionic strength. Buffer systems, their mechanism and biological significance.
2
6 Electroconductivity and kinds of electrolyte’s solutions. Kohlrausch’s law. Conductometric titration. EMF and electrode potentials: diffusive, membrane, oxidation and redox potentials. Nernst-Peters equation. Structure Yakobi- Daniell’s galvanic element. Concentration and Veston’s element.
2
7 Chemical kinetics and catalysis. Formation and molecularity of reactions.T ypes of complex reactions. Quantum yield, the role of the chain and photochemical reactions in biological processes. Catalysis and catalyst. Theory of catalysis. The kinetics of enzymatic reactions.
2
8 Classification of electrods: reference and definition electrods. Potentiometric titration and polarography.
1
Total hours 15
The plan of lectures on microbiology and immunology forthe students of pharmacy faculty for winter term
1 Introduction to basic microbiology. The causative agents of inflammatory diseases (pathogenic cocci and opportunistic bacteria). Pathogenic anaerobes
2
2 The causative agents of intestinal and zoonotic infections
2
3 Genus Haemophilus, Bordetella, Legionella, Corynebacterium, Mycobacterium and Actinomyces
2
4 Pathogenic Spirochetes, Rickettsiae, Chlamydiae and Mycoplasma
2
5 Pathogenic fungi and protozoa 26 Introduction to basic virology. The causative agents of
respiratory viral infections (orthomyxoviruses and paramyxoviruses). Herpes viruses, picornaviruses and rhabdviruses
2
7 Hepatitis viruses. Human immunodeficiency viruses 229
Total hours 14
The plan of practical training on microbiology and immunology for
the students of pharmacy faculty for winter term
1 The main principles of microbiology diagnosis of infection diseases. Microbiology diagnosis of diseases, caused by staphylococci and streptococci
2
2 Microbiology diagnosis of diseases, caused by pathogenic Neisseria
2
3 Microbiology diagnosis of diseases, caused by opportunistic bacteria (Klebsiella, Proteus, Pseudomonas aeruginosa)
2
4 Microbiology diagnosis of diseases caused by Escherichia coli and Salmonella
2
5 Microbiology diagnosis of dysentery and cholera 26 Microbiology diagnosis of zoonotic infections (plague,
7tularemia, brucellosis and anthrax)2
7 Microbiology diagnosis of diseases, caused by anaerobes (genus Clostridium and Bacteroides) – 2 h
2
8 Microbiology diagnosis diphtheria, tuberculosis and actinomycosis
2
9 Microbiology diagnosis of diseases, caused by Spirochetes
2
10 Microbiology diagnosis of diseases, caused by Rickettsiae, Chlamydiae and Mycoplasma
2
11 Microbiology diagnosis of mycosis and parasitic infections
2
12 Introduction to basic virology. Microbiology diagnosis of respiratory viral infection
2
13 Microbiology diagnosis of infections, caused by herpes viruses and enteroviruses
2
14 Microbiology diagnosis of viral hepatitis and Acquired Immunodeficiency Syndrome (AIDS) – 2 h
2
15 Conclusion lesson 2
30
Total hours 30
Thematic plan of practical training on physical chemistry (autumn semester)
№ Topic hours 1. Chemical thermodynamics. I laws of
thermodynamics, application in biological systems. Thermochemistry. Methods of calculating the thermal effect of the chemical reaction. Calorimetr, working principle. Determination of solubility and neutralization heat by calorimetric method.
4
2. The II and III laws of thermodinamics. Entropy, its change in various processes. Nernst’s equation. Plank’s postulate. Entropy and probability.Thermodynamic potentials. Hibbs-Helmhots equation for maximal useful work. The provment of possibility of the reaction on the basis of this equation.
4
3. Thermodynamics of chemical equilibrium. Law of interaction of masses for homogene and heterogene equilibrium. Isothermal, isochoric, isobaric equations of chemical reaction. Determination of equilibrium constant of etherification reaction(C2H5OH and CH3COOH). Solving of problems on chemical equilibrium.
4
4. Theory of electrolites. İsotonik coefficient (“i”). Dissosiation of water and its ionic product. Determination of dissosiation degree and equilibrium constant of weak acid (CH3COOH). Determination of pH in weak and strong electrolite solution.
4
5. Buffer solutions, their mechanism. Buffer capacity. The influence of acid and base to pH buffer solutions. Determination of pH of different solutions by colorimetric, electrometric methods.
4
6. Cryoscopy and ebulioscopy. Bekman termometer. Determination of molecular mass of glucose solution by cryoscopy.
4
7. Dissolution of liquids in earch other. Distribution of 4
31
asetic acid between water and benzene. 8. Survey of material. 4 9. Surface tension, its definition. Determination of
surface tension of different compounds. Rebinder instrument and structure.
4
10. Conductivityof solutions. Kohlrausch’s law.Conductometric titration. Conductometric titration of mix of strong and weak acid (HCl+CH3COOH) by strong base solution.
4
11. Electrod potentials and prosesses. Determination of EMF of Yakobi-Daniell’s galvanic element. Determination of oxidation-redox potential. Problems for redox potential.
4
12. Classification of electrodes: reference and definition electrods. Potentiometric titration and polarography. Determination of pH of different solutions by potentiometric method with glass electrod.
4
13. Chemical kinetic and catalysis. Mono- and diorders reactions. Activation energy. Equation of Arrenius. Investigation of sucrose hydrolysis.
4
14. Catalysis and catalyst. The enzymatic catalysis and its particularity. Kinetic of enzymatic reactions. Labor. work: Analysis of decomposition reaction of H2O2.
4
15. Survey of material. Final lesson. 4Total hours 60
Thematic plan of lectures oncolloidal chemistry (spring semester)
№ № Topic hours
1. 1. The subject and content of colloid chemistry. The colloid state of substanse. Classification (on the different features) and molecular-kinetic properties of dispersed systems. Preparation and purification of dispersed systems
2
2. Optical properties of dispersed systems. Micellar structure
32
heory of colloid particles. The structure of electrical double layer. Electrokinetic phenomena of dispersed systems. Application of electrophoresis and electroosmosis in medicine.
2
3. Stability and coagulation of dispersed systems. Coagulation of colloid solutions by electrolytes. Stabilization of colloid solutions.
2
4. 4. Surface phenomena, surface tension. The kinds and theories of adsorption. Chromatography and its kinds.
2
5. Classification, structure, swelling, solubility and visc osity of HMC. The factors influencing the eelling. Vis cosity, kinds and methods of determination. Em ulsions and sus-pensions. Emulsifiers. Transfarmation law of emulsion phases.
2
Total hours 10Thematic plan of practical training on
colloidal chemistry (spring semester)
№№ Topic hours 1. Colloids.The colloid state of substanse. 42. Preparation and cleaning of colloid solutions. 43. Coagulation of colloid systems 44. Stability of colloid systems 25. Optical properties of colloid solutions. Research of optical properties
by microscop. 2
6. Electrokinetic properties of colloid solutions: ele electrophoresis and electroosmosis.
2
7. Molecular-kinetic properties of colloid solutions. 28. Survey of material. 29. Scheme of the structure of the sol micelle AgCl. 210. Surface phenomena. Surface tension. 211. Adsorption, Freundlich adsorption isotherm. 212.12. Chromatography and its kinds. Analisys of medicines by different methods of chromatography.
2
13. Emulsions and suspensions. Btaining, Obtaining, destruction and transfarmation of emulsions. Emulsifiers.
2
14. The mechanism of swelling’s kinetic of polymers. Preparation, properties, swelling, solubility of HMC. The factors influencing the sweelling.
2
15 The kinds of viscosity. Definition of molecular mass of different compounds by Ostvald viscosimeter.
1
Total hours 29
The plan of lectures on “Hygiene of pharmaceutical premises”
33
N Themes Hours1 Hygiene as a base of prophylactic discipline. Hygiene of
pharmaceutical premises as one of branches of hygienic science. The development of hygiene in Azerbaijan. The main problems of hygiene and ecology. Methods of investigation using in hygiene. The role of hygienic knowledge at pharmacological work
2
2 Hygienic characteristic of atmospheric air. Physical, chemical and biological parameters of air, their influence on human organism. Sun radiation and it hygienic meaning. The whether, climate and microclimate. The influence of getting worse modern ecological condition on population health. Specific properties of air of pharmaceutical premises. Prophylactic measures directed to prevent the influence of air pollution
2
3 Water as environmental object, physiological, hygienic and epidemiological meaning of water. Sources and systems of water supply, their hygienic characteristic. Hygienic estimation and norms of quality of water. Methods of clearing and disinfection of water. The influence of water on a quality of herbs
2
4 Soil as biosphere object. Mechanical, chemical and physical parameters of soil, their hygienic meaning. The influence of chemical composition of soil on man health and quality of medicine plants. Self-clearing of soil. Sanitary protection of soil
2
5 Physiological and hygienic base of feeding. Rational, dietary and prophylactic nutrition. The scientific-technological progress and actual problems of nutrition hygiene. Peculiarities of feeding when taking medicine. Hygienic characteristic of essential nutrients and food products. Food poisons and their prophylaxis
2
6 Physiological-hygienic base of work. Fatigue and over-fatigue, their prophylaxis. Occupational harms and occupational diseases. Industrial dust, their influence on organism. Dust of medicine as specific industrial harm, influence on organism and prophylactic measures. Prophylaxis of professional poisons and occupational diseases
2
7 Hygienic peculiarities of technological processes and workplace conditions at medicine production (solutions, drugs, ampoules, powders, pills, antibiotics). Hygienic requirements to the building and equipments of chemists and control-analytic laboratories. Sanitary-educational work of pharmaceutical premises
2
Total hours 14
The theme plan of lectures of «Pharmaceutical botany- 2”on the spring term
№ Topics of lectures Hours
34
1 Angiosperms. The main systems of Angiosperms Class Magnoliopsida. Subclasses: Ranunculidae, CaryophyllidaeHamamelididae, Dilleniidae, Rosidae, Lamiidae, Asteridae.
2
2 Class Liliopsida, Subclasses: Alismatidae, Arecidae, Liliidae, Commelinidae
2
3 Fundamentals of botanical geography, a brief overview of the history and sections. The concept of habitat. Formation of the habitats. Endemics and cosmopolitans. The concept of the flora. Floristic zones of the Earth . The mainelements of the flora of Azerbaijan.
2
4 The main elements of plant ecology. The main environmental factors affecting to the growth of the plants. Plant introduction. The concept of the life form. Systems of the life forms of the plants. Phytocenology elements. Plant communities, their formation. Vegetation zones and major vegetation types of the Earth. The vegetation cover of Azerbaijan
2
Total hours 8
The theme plan of the laboratory classes of “Pharmaceutical botany – 2”on the spring term
№ Topics of the laboratory classes Hours1 Magnolidae subclass: Magnoliaceae,Schizandraceae,
Lauraceae, Nymphaeaceae familiesRanunculidae subclass: Berberidaceae, Ranunculaceae,Papaveraceae families.
4
2 Caryophyllidae subclass: Caryophyllaceae,Chenopodiaceae, Polygonaceae familiesHamamelididae subclass: Fagaceae, Betulaceae families.
4
3-4 Dillenidae subclass: Theaceae, Clusiaceae, Passifloraceae, Violaceae, Cucurbitaceae, Brassicaceae, Ericaceae, Tiliaceae, Primulaceae, Malvaceae, Urticaceae, Euphorbiaceae families.
8
5-6 Rosidae subclass: Saxifragaceae, Crassulaceae, Rosaceae, Fabaceae, Myrtaceae, Rutaceae, Anacardiaceae, Hippocastanaceae, Linaceae, Rhamnaceae, Elaeagnaceae,Araliaceae, Apiaceae, Valerianaceae,Caprifoliaceae families.
8
7-8 Lamiidae subclass: Rubiaceae, Apocynaceae, Asclepiadaceae, Gentianaceae, Menyanthaceae, Fabaceae, Polemoniaceae Oleaceae, Scrophulariaceae, Plantaginaceae, Lamiaceae
8
35
families.Asteridae subclass: Asteraceae family.9 Class Liliopsida. Liliidae subclass: Liliaceae,
Alliaceae,Orchidaceae,Amaryllidaceae, Asphodelaceae,Agavaceae,Convallariaceae, Asparagaceae, Dioscoreaceae families.Class Commelinidae: Poaceae family.families.
4
10 Concluding lesson. 1Total hours 37
The plan of lectures on medical merchandising for the students (spring term)
№ Themes Hours1 Medical commodity science as discipline. Goals and objectives of
medical merchandizing. Common notions about medical products. Historical development of medical commodity science
2
2 Classification of medical goods. Main requirements for medical commodities. Quality parameters. Materials used in medical practice. Medical materials science. Metals and polymers used in medical practice
2
3 Modern diagnostic methods. Equipment used in medical diagnostics 2
4 Modern surgery methods. Equipment. Cryosurgery. Minimal-invasive surgery. Medical laser technics
2
5 Equipment used in medical prophylactics (prevention) and rehabilitation
2
6 Common vision defects. Geometrical optics. Ophthalmological medical devices
2
7 Marketing of optical goods. Optical shop 2
Total hours 14
The plan of practical training on medical merchandising for the students
(spring term)
№ Themes Hours1 Bandages and bandage materials. Quality parameters. Types and
sorts of bandages. Synthetic bandages2
2 Medical threads and sutures. Classification of sewing materials. Quality requirements
2
3 Medical clothing and accessories 2
4 Medical rubber goods. Patient care devices. Orthopedic devices 3
5 Medical devices for injections and infusions. Disposable (throw-away) medical goods
2
36
6 Diagnostic tests, simple medical devices 2
7 Medical laboratory devices 2
8 Classification of surgical tools. Storage of surgical instruments 2
9 Dental instruments and equipment. Dental materials 2
10 Optic lenses. Lenses classification. Types of lenses 2
11 Optic devices used for vision correction. Materials used for lenses manufacturing
2
12 Classification of spectacles. Sun glasses, safety glasses 2
13 Contact lenses. Specificity of using. Types and sorts 2
14 Appliances and equipment used in optical shop 3
Total hours 29
Program of lectures by “dynamic and functional biochemistry”
(spring term)
N. Subject of lesson Hour
1.General pathways of katabolism (I and II pathways), its energetiic value. Bioligical oxidation. Structure and function of electron transporting chain (ETC).
2
2.
Digestion and uptake of carbohydrates. Synthesis and breakdown of glycogen. Glycolysis. Aerobic glycolysis. Pentosephosphate pathways of carbohydrates oxidation. Glyconeogenesis. Carbohydrate metabolism disturbances.
2
3.Digestion of proteins. Conversion of aminoacids by the action of interstinal microflora. Formation of ammonia in orqanism. Mechanism it's toxicity and detoxification. Protein synthesis.
2
4.Synthesis and degradation of hemoglobin. Formation of bile pigments. Jaundices. Metabolism of nucleoproteins. Metabolism and disturbance of purine and pirimidine nucleotides.
2
5.
Digestion of lipids. Resynthesis of lipids in intestine. Oxidation of fatty acids. Metabolism of ketone body. Synthesis of cholesterol. Disturbance of lipis metabolism. Hereditary lipidosis. Metabolism of drugs.
2
Total hours 10Program of practical lessons by
“dynamic and functional biochemistry” (spring term)
N. Subject of lesson Hour1 Introducing with thematic plan. 2
37
2 The basic metabolic pathways. Respiratory chain.Experiments: Qualitative and quantitative determination of catalase. Determination of enzyme succinatedehydrogenase.
2
3 Colloquium: The basic metabolic pathways. Energetic metabolism. Structure and function if the cell membranes. 2
4 Metabolism of carbohydrates. Digestion of carbohydrates. Glycolysis and gluconeogenesis. Diabetus mellitus.Experiments: Determination glucose in blood.
2
5 Colloquium: Metabolism of carbohydrates. Passing a free topics. 2
6 Digestion and conversion of aminoacids.Experiments: Analysis of gastric juice. Protein digestion by pepsin and trypsin.
2
7 General and specific pathways of aminoacids metabolism. Synthesis of urea. Disorders of aminoacids metabolism. Experiments: Determination of urea in blood. Determination of ALT and AST activity.
2
8 Colloquium: Metabolism of simple proteins and aminoacids.Passing a free topics. 2
9 Metabolism of complex proteins. Synthesis and degradation of hemoglo-bin. Degradation of purin nucleotides. Experiments: Determination of hemoglobin in blood. Determination of bilirubin in blood.
2
10 Colloquium: Metabolism of complex proteins. Protein synthesis. Passing a free topics.
2
11 Metabolism of lipids. Digestion of lipids. Synthesis of cholesterol. Disorders of lipid metabolism.Experiments: Qualitative determination of bile acids.Determination of cholesterol.
2
12 Colloquium: Metabolism of lipids.Passing a free topics. 2
13 Biochemistry of blood liver and urine. Metabolism of drugs.Experiments: Determination the total proteins in blood. Analysis of urine.
2
14 Colloquium: Biochemistry of liver, blood and urine. Passing a free topics. Metabolism of drugs 2
15 Passing a free topics. Summary of dynamic biochemistry. Calculation of points. 2
Total hours 30 Latin language II-term (spring)
№ The main themes of the practical classes hour
38
1 I group adjectives, exercises, wordsI group adjectives, exercises, words
22
2 Exercises on agreement of II group adjectives with different declinations of nouns
Adjectives belonging to the active voice of the Present Tense
2
2
3 Degrees of adjectives. Exercises Irregular degrees of adjectives
22
4 IV declination of nouns.Coordination of adjectives with IV declination of nouns.
2
25 V declination of nouns. Exercises.
Coordination of adjectives with V declination of nouns.
2
2
6 V declination of nouns.Exercises Coordination of adjectives with V declination of nouns.
22
7 Translation and analyses of sentences. Adverbs. Pronouns
22
8 Adverbs used in recipes Numerals. Conjunctions used in recipes
22
9 Translation and analyses of sentences. Clinical terminologies
2
10 Exercises on clinical terminologies. Exercises used in recipes
2
11 Abbrevations and full forms of medicinal means in recipes. Recipes on all types of medicinal forms
2
12 Recipes on infusion and decoction Recipes on tinctures and mixtures
2
13 Recipes on medicinal forms Recipes on candles and extracts
2
14 Recipes on injections. Recipes on species and mixtures.
2
15 Total lesson. 1
Total hours 45
39
III course
Thematic plan of lectures on toxicological chemistry (spring semester)
№ Topic hours
40
1. 1. Subject of toxicological chemistry, goals and aims. Сhemi-cal toxicological analysis and species. Relationship to other subjects. Objects and specifity of chemical toxicological analysis.
2
2. 2. A preliminary study of the objects of research. Methods of chemical toxicological analysis.
2
3. The poison, poisoning and its species. Influencing factors. 2
Thematic plan of laboratory studies on toxicological chemistry (spring semester)
№ Topic hours 1. The reagents used in toxicological chemistry and verification
of purity. Rules of laboratory work. Sending and taking of evidence to the chemical-toxicological analysis. The primarysamples of chemical-toxicological analysis. Methods of isolation, purification, detection and determination of toxic substances from a biological objects. The group of poisonous substances, isolated by distillation method with water vapor. Volatile poisons.
4
2. 1. Cyanic acid, its chemical and toxicological specificity. Isolation,detection and determination of it from biological material.Organochlorine compounds: chloroform, carbon tetrachloride, chloral hydrate, dichloroethane, ethyl chloride, trichloroethylene. Chemical-toxicological specificity, isolation, detection and
determination.
4
3. Chemical-toxicological specificity, isolation, detection and determination of formaldehyde, acetone, acetic acid and its anhydride. The aliphatic alcohols. Ethanol, methanol, isoamyl alcohol. Ethylene glycol and chemical-toxicological specificity,
isolation, detection and determination.
4
4. 2. Phenols, derivatives and chemical-toxicological analysis. Verification work. Writing and discussion of forensic chemicalexpertise act on the basis of chemical control work. Survey traversed lessons.
4
5. 3. Substance, isolated by mineralization. General and particular methods of mineralization. Chemical-toxicological analysis of 4. metallic poisons. Analysis of the compounds of barium and
lead.
4
6. 5. Analysis of the compounds of chromium and manganese. 2 7. 6. Analysis of copper and silver. 2 8. 7. Analysis of arsenic compounds. 2 9. 8. Analysis of bismuth and stibium compounds. 2 10.9. Analysis of zinc, cadmium and thallium compounds. 2
41
11. Analysis of mercury and its compounds. 2 12. Substances, isolated from the biological material by the water.
Mineral acids. 2
13. Сhemical-toxicological analysis of alkalis and salts. 2 14. Gaseous toxic substances and their chemical-toxicological
analysis. 2
15. The final lesson. 1
The theme plan of Laboratory Classes on Pharmacognosy- 2in spring term
№ The plant crude drug formorphological analysis Hours
1 Medical plant and the raw material,containing saponins.
1. Licorice root2. Field horsetail grass
impurity and its impurities3. Rhizomes with roots of yam4. Horse Chesnut seeds
Ginseng roots, the roots of Aralia Manchurian, rhizomes with roots of ehinopanaks high.
4
2 The analysis of saponins in the drug raw material 43 Medical plant and the raw material,
containing anthracene derivatives and their glycosides1. Sennas leafes2. Buckthorn bark3. Rhineberry fruits and possible impurities4. Aloe tree leafes
4
4 1. Rhubarb roots2. St John's wort grass3. Sorrel horse root4. Madder dyeing rhizome and root
The analysis of anthracene derivatives in the drug raw material
4
5 Medical plant and the raw material,containing flavonoids
1. Sandy Everlasting flowers2. Water pepper grass3. Redshank grass4. Common Knotgrass grass5. Cottonweed marsh (Marsh Cudweed) grass
4
6 1. Tansy flowers 4
42
2. Hawthorn flowers and berries(fruits)3. Linden (lime) flowers4. Trifid Bur-Marigold grass5. Licorice root
7 1. Harrow the fiel roots2. Astragalus dasyanthus grass3. Baikal Skullcap roots4. Cornflower blue flowers5. Field horsetail grass
4
8 1. Sophora of Japanese flower buds and fruits2. Motherwort grass
Citrous fruits hulls, tea-plant leaf, black chokeberry fruits. 4
9 The analysis of flavonoids in the drug raw material 410 Medical plant and the raw material,
containing coumarins and chromons1. Garden dill fruits2. Fig tree leafes3. Parsnip seeds4. Ammi visnaga fruits
Horse chesnut seeds, greater ammi, scurfy pea.
4
11 Medical plant and the raw material,containing tannins
1. Sumac leaf2. Smoketree leaf 3. Oak bark
Alder seedheads, common tormentil(cinquefoil erect) rhizomes, serpentine root, burnet, bergenia, blueberry, galss, bird cherry tree .
The analysis of tannins.
4
12Medical plant and the raw material,containing little-studied biologically active substances
1. Polypore2. Kalanchoe3. Kidney tea4. Eucommia5. Raspberry6. Maral root (Rhaponticum)7. Peony
4
13 Medical plant and the raw material,Containing fatty oils
1. Olive fruits2. castor-oil plant seeds3. cocoa oil
4
43
Oils: almond's, apricot, peach, peanut, sunflower, corn, cotton-seed, flax, beechwood.Final lesson.
The theme plan of the lectures on Pharmacognosy 2 spring term
№ The topic of the lecture Hours
1 Saponins and anthracene derivatives and their glycosides. General characteristics, chemical structure, classification, phisico-chemical properties, spreading in the plants, the accumulation and role in plant. The role Azerbaijan and foreign scientists in investigation of medical plants, containing saponins and anthracene derivatives.
2
2 Flavonoids. General characteristics, chemical structure, classification, phisico-chemical properties, spreading in the plants, the accumulation and role in plant. The role Azerbaijan and foreign scientists in investigation of medical plants, containing flavonoids. Localization and physiological roles in plant life. The influence of the phase of vegetation and environmental factors on the formation of the plants, especially the drying and storage of raw materials.Flavonoids and using in medicine. The role of foreign and Azerbaijani scientists in the study of medicinal plants containing flavonoids.
2
3 Coumarins and chromons . Tannins. General characteristics, chemical structure, classification, phisico-chemical properties, spreading in the plants, the accumulation and role in plant. The role Azerbaijan and foreign scientists in investigation of medical plants, containing coumarins.
2
4 Fatty oils, physical and chemical characteristics,classification, the variability of the composition and properties of fatty oils, methods of preparation and use.Medicinal plants and raw materials containing differentbiologically active substances.
2
The Theme Plan of the Laboratory Classes on “Pharmocognosy - 1” course autumn term
44
№ The morphological research of the medicinal plants raw material Hours
1. The macroscopic of plant raw material samples from different morphological groups.
4
2. The microscopic of plant raw material samples from different morphological groups.Study of the histological and qualitative reactions on plant raw material, containing different biologically active substance groups.
4
3. The medical plants and raw materials, containing polysaccharides 1. Plantain leaves 2. Marshmallow root 3. Coltsfoot leaves 4. Kelp 5. Elecampane
4
4. 1. Flaxseed2. Tragacanth3. Apricot gum4. Dandelion5. Quince6. Cotton.
4
5. The medicinal plants and raw materials containing vitamins.1. Wild rose fruit2. Nettle leaves3. Calendula flowers4. Sea buckthorn5. Rowan ordinary6. Tickseen7. Mouse-ear.
4
6. 1. Corn stigma
2. Shepherd's purse leaves
4
45
3. Black currant
4. Snowball tree 5. Walnut 6. Cabbage 7. Pumpkin 8. Carrot
Quantitative determination of ascorbic acid in rose hips (by X MPh ed.) And chromatographic determination of ascorbic acid and carotenoids in fruits of wild rose and calendula flowers.
7. The medicinal plant and raw materials containing volatile oils1. Coriander fruit2. Mint leaves3. Sage leaves4. Caraway fruit
4
8. 1. Eucalyptus leaves2. Valerian rhizome and root and candidate admixture3. Chamomile flowers and candidate admixture4. Juniper fruits
4
9. 1. Camphor getting source2. Santonic flowers3. Birchen bud 4. Wormwood herb 5. Milfoil herb
4
10. 1. Thyme herb 2. Origanum herb3. Fennel fruit4. Anise fruit5. Sweet flag6. Arnica7. Wild rosemary
4
11. The medicinal plants and raw materials, containing thioglycosides, iridoids and cyanicglycosides.1. Mustard seed 2. Almond seed
4
46
3. Centaury herb 4. Dandelion root5. Hop dull ends
12. The medicinal plants and raw materials, containing phenol glycosides and lignanes and other phenol substances.1. Bearberry leaves and candidate admixture2. Cowberries leaves3. Violet herb4. Rosewort 5. Male fern rhizome and candidate admixture6. Chinese magnolia-vine7. Siberian Ginseng 8. May-apple
4
13. The medicinal plants and raw materials, containing cardio glycosides.1. Lily of the valley herb, flowers and leaves , Candidate admixture.2. Strophanthus seed3. Adonis herb and candidate admixture4. Digitalis leaves Cardio glycosides analysis.Conclusion lesson.
4
The Theme Plan of the Lectures on “Pharmocognosy 1” autumn term
№ The topic of the Lectures Hours1 The definition of pharmacognosy as a science
and educational subject. The main conceptions: medical plants, medical raw plants, the raw of animal origin. The connection with basic and profile pharmacists’
2
47
practical activity methods of medical raw plants’ pharmacognosical investigations. Plants’ chemical composition. Biological active and attendant substances of the medical plants. Primary and secondary metabolites. The ways of biosynthesis of secondary.Changeability of medical plants’ chemical composition in the process of ontogenesis and under the influence of ecological factors.The system of classification of medical plants: chemical, morphological, botanical and pharmacological.
2 Medical plants and the raw, containing polysaccharide, photosynthesis and the products of carbohydrates convention the basic of biologenes of biologically active substances in the plants. Chemical composition, physicochemical properties of starch, inulive mucus, gums, pectine substances and cellulose. The ways of their usage in medicine. Vitamins. Spreding in the plants, the dynamics of accumulation in plants, the influence of external factors, classification the peculiarities of preparation of the raw, rich with vitamins.
2
3 The conception of terpenoids.Volatile oil. The general characteristic of volatile oil, the classification, physicochemical properties, speading in the plant, world, localization and role in the plants’ life. The dynamics of accumulation of volatile oil in the plants, the influence of external environment on the content of volatile oil. The peculiarities of their preparation, drying and keeping of volatile oil raw, methods of secretion and analysis of volatile oil, the ways of its usage in medicine.The role of Azerbaijan and foreign scientist in the investigation of medical plants, containing volatile.
2
4 Glycosides.Their characteristic, special features, of their structure and classification.
2
48
Iridoids. Hear glycosides. The peculiarities of chemical structure, of phisico-chemical properties, classification, speading in the plant world, the influence of vegetation and envizonment factors on glucoside composition of the raw, the peculiarities of preparation, methods of raw voilution, containing heart glucoside, their usage in medicine. The role and importance of works of our and foreign scientist in investigation of medical plants, containing heart glucoside.
Program of laboratory lessons of biochemistry autumn semester
N Subject of lessons Hours
1. Acquaintance with group, department security technique rules, laboratory equipment and main problems static biochemistry. 4
2.
Classification, chemistry and biological functions of carbohydrates and lipids.Lab. work: Reactions of monosaccharides. Hydrolysis of starch. Emulsification. Definitions of unsaturated fatty acids. Quantity reactions of cholesterol.
4
3.
Structure of amino acids, physico-chemical properties, nature of peptide bond.Lab. work: Chromatografy of amino acids on paper. Color reactions of amino acids.
4
4. Colloquium: Chemistry, functions of carbohydrates, lipids and amino acids. Passing of free themes. 2
5.Structure physico-chemical properties of proteins.Lab. work: Precipitation reactions of proteins. Definitions of iso electric points of proteins. Hydrolysis of protein: Biuret reactions.
4
6.Structure and functions of conjugated proteins. Lab. work: Reactions of phospho-, qlyco- and chromo proteins. Hydrolysis of nucleoproteins.
4
7. Colloquium: Chemistry of proteins and nucleic acids. 2
8.Structure and properties of enzymes. Lab. work: Termolability, spesifity, of optimum pH of enzymes. Kinetic of lipase activity.
4
9.
Activators and inhibitors of enzymes. Regulation of enzymatic activity.Lab. work: Definition of amylase activity by Karavey methods. Influence of activators and inhibitors on amylase activity.
2
10.Classification, structure and biological functions of vitamins. Lab. work: Reactions of vitamin: A, B1, B2, B6, PP. Quality and quantity definition of vitamin C.
4
49
11. Colloquium: Enzymes and vitamins. The accepting of free themes. 2
12.Structure, mechanism of influence and biological functions of hormones.Lab. work: Reactions of tiroksin, adrenalin and insulin.
4
13. Seminare: Hormones. 2
14. Colloguium: Chemical nature, mechanism of influence and biological functions of hormones. The accepting of free themes. 2
15. Finely balls for semester. The accepting of free themes. 2
Thematic plan of lectures and laboratory studies on toxicological chemistry spring semester
№ Topic hoursLectures
1. 3. Subject of toxicological chemistry, goals and aims. Сhemi-cal toxicological analysis and species. Relationship to other subjects. Objects and specifity of chemical toxicological analysis.
2
2. 4. A preliminary study of the objects of research. Methods of chemical toxicological analysis.
2
3. The poison, poisoning and its species. Influencing factors. 2
Laboratory studies 1. The reagents used in toxicological chemistry and verification
of purity. Rules of laboratory work. Sending and taking of evidence to the chemical-toxicological analysis. The primarysamples of chemical-toxicological analysis. Methods of isolation, purification, detection and determination of toxic substances from a biological objects. The group of poisonous substances, isolated by distillation method with water vapor. Volatile poisons.
4
2. 10.Cyanic acid, its chemical and toxicological specificity. Isolation,detection and determination of it from biological material.Organochlorine compounds: chloroform, carbon tetrachloride, chloral hydrate, dichloroethane, ethyl chloride, trichloroethylene. Chemical-toxicological specificity, isolation, detection and
determination.
4
3. Chemical-toxicological specificity, isolation, detection and determination of formaldehyde, acetone, acetic acid and its anhydride. The aliphatic alcohols. Ethanol, methanol, isoamyl alcohol. Ethylene glycol and chemical-toxicological specificity,
isolation, detection and determination.
4
4. 11.Phenols, derivatives and chemical-toxicological analysis. Verification work. Writing and discussion of forensic chemical
4
50
expertise act on the basis of chemical control work. Survey traversed lessons.
5. 12.Substance, isolated by mineralization. General and particular methods of mineralization. Chemical-toxicological analysis of 13.metallic poisons. Analysis of the compounds of barium and
lead.
4
6. 14.Analysis of the compounds of chromium and manganese. 2 7. 15.Analysis of copper and silver. 2 8. 16.Analysis of arsenic compounds. 2 9. 17.Analysis of bismuth and stibium compounds. 2 10.18.Analysis of zinc, cadmium and thallium compounds. 2 11. Analysis of mercury and its compounds. 2 12. Substances, isolated from the biological material by the water.
Mineral acids. 2
13. Сhemical-toxicological analysis of alkalis and salts. 2 14. Gaseous toxic substances and their chemical-toxicological
analysis. 2
15. The final lesson. 1
The plan of lectures on pharmaceutical chemistry-1 (autumn term)
N Themes Hours1 Subject of pharmaceutical chemistry and its duties.Resources of
receiving drug substances.Standard-technical documents.Inorganic and organic drug substances analysis.The general rules of medicines cleaning identification.Classification of drug substances.Inorganic compounds: oxygen, hydrogen peroxide, hydroperit, preparates of water. Halogens with alkali metals compounds
2
2 Preparates of calсium,magnesium,barium,aluminium and borum compounds. Preparates of bismut, zinc, mercury, silver, copper, iron and platin compounds. Radiopharmaceutical preparates.
2
3 Organic drug substances.Aliphatic compounds.Derivatives of halogens,spirits and its ethers.
2
4 Aldehids, saccharids, carbon acids and its derivative's preparates.Laktons of policarbon acids.Amino acids and its derivatives.
2
5 Uretans and ureids. β-laktamids. Sefalosporins.Aminoqlikozids. 2
The plan of practical training on pharmaceutical chemistry-1 (autumn term)
N Themes Hours1 The general reactions of identification ions (kations, anions,
functional groups)Check of ions ‘hybrids and its acceptable limit.
4
51
2 The general analysis methods of organic medicine preparetes (the nature of substance,the temperature of smelting and boiling and determination of density)Determination of dissolution,water,ash,the colour of solutions,transparency,sediment. Physical,chemical and physico-chemical methods of quality determination of medicine preparates (polarimetry, refraktometry, photokolorimetry, spectrophotometry and others. Control work
4
3 The analysis inorganic medicine preparates. Water purification. Halogens with alkali metals compounds, sodium hydrocarbonate.Calсium and magnesium compounds
4
4 Bor, bismuth and zinc compounds.Mercury, silver, copper and iron compounds. Control work.
4
5 Analysis of aliphatic acyclic compounds:a) Halogen derivatives of carbohydrogens,spirits,ethers (iodoform,aethyli alcohol,nitroglycerin-tablets and etc)b) Aldehids and its derivatives (chloral hydrat,metenamin, hexamethylentetramin) - substance). Carbohydrates (glucose – substance, sucrose - substance )c) Carbon acid and its derivativies,(calсium-laktat – substance, sodium-citrate - substance, potassium-gluconat - substance, calсium-pangamat-tablets, calcium-pantotenat - tablets)d) Laktons of unsaturated policarbon acids (ascorbin acid - substance, solution pro injection ) Amino acids and its derivatives (glutamine acid- substance, methionin – tablets)e) Urctans and acyclic ureids.Natural and halfsynthetic penicillins (benzylpenicillin-sodium and potassium salts)/ Aminoglikozids/streptomycin – sulfat/. Control work.
4+4
4
4+4
2
22
2 2
The plan of lectures on pharmaceutical chemistry-2 (spring term)
N Themes Hours1 Aliphatic cyclic compounds. Adamantane derivatives. Terpenoids. 22 The derivatives of cyclopentanperhydrophenantren (steroid
compounds). Cyclohexanolethylenhydrindan compounds.Calceferols. Ergocalciferol and cholecalciferols . Cardenolids (cardiac glycosides).Estrogens and its syntethic analogues: Progesterone and and its synthesis possibilities. Аndrogens and anabolics. Corticoseroids. Estrogens.
2
3 Aromatic compounds. Phenol, quinons, amines and its derivatives.Non-steroidal nature synthetic estrogens. Quinons. The derivatives of naphthoquinone (vitamins of K group).Brom-arylamine group preparations. Теtracyclines. The derivatives of aureol acid (antitumor antibiotics).
2
52
Para-aminophenol derivatives as non-narcotic analgesics Аromatic alcahols (benzhydrol) derivativers. Butirophenon derivatives. Аromatic acids and its derivatives. Para- and оrto-aminobenzoic acids and its’ derivativers. Diethylaminoacetanilids. The derivatives of amides of para-aminobenzoic acid.
4 Aromatic compounds. The derivatives of para-aminosalicylic acid. The derivatives of ortho-aminobenzoic (anthranilic) acid Аrylalkylamines.Оxyphenylalkylamines,nitrophenylalkylamines and its’ derivatives. Phenylalkylamines.Aromatic compounds. The derivatives of ariloxypropanolamines(beta-adrenoblocators). Оxyphenylaliphatic animoacids. The iodine derivatives of aromatic and аrylaliphatic aminoacids . Iodo-arylaliphatic aminoacids.
2
5 Aromatic compounds. Benzolsulphanilamides and its’ derivatives. Sulphanilamides. Salazosulphanilamides..The amide derivatives of chlorbenzolsulphonic acid. Sulphonilcarbamide derivatives as antidiabetic preparations. . Benzolsulphochloramide derivatives.
2
The plan of practical training on pharmaceutical chemistry-2 (spring term)
N Themes Hours1 Analysis of aliphatic cyclic compounds : mentholum, terpinum
hydratum, bromcamphora. Analysis of cardiac glycosides (cardenolids): digitoxine, сelanide, isolanide, digoxine. Analysis of androgen, anabolic and estrogen action preparations : methyltestosteron, testosteron, methandrostendiol, еthinylestradiol. Carring out of test-tasks and free works for aliphatic cyclic compounds.
444
2 Аnalysis of aromatic compounds. Phenol, qunons and its derivatives: resorcinol, vikasolum and sinestrolum and its drug forms. Carring out of test-tasks and free works for phenols, qunons. Analysis of para-aminophenol derivatives: paracetamol – tablets.Tetracyclines and para-аminophenols.
444
3 Аromatic acids and amino acids, analysis of preparations of its derivatives: benzoic acid, sodium benzoate, sodium-salicylate, oxaphenamid, acetylsalicylic acid, procaine hyrochloride, sodium para-aminosaicylate, bepascum and its medicine forms.Carring out of test-tasks and free woks for aromatic acids and its derivatives, Analisys of phenylalkylamines and nitrophenylalkylamines group preparations: adrenaline tatrate and isadrine and its drug forms.Carring out of test-tasks and free works for phenylalkylamines, β-adrenoblocators, nitrophenylalkylamines: preparations for roentgeno
44442
53
and iodine derivatives of amino acids.4 Analysis of sulphanilamides preparations: norsulfazolum,
urosulfanum, phthalazolum, sulfalene, salazopiridazine and its medicine drugs. Carring out of test-tasks and free works for sulphanilamides and salazosulphanilamides. Chlorsulphonic acid, the derivatives of sulfonylcarbamid and benzolsulphocloramide and its analysis: butamide, bucarbanum, cloramine B and its medicine forms.Carring out of test-tasks and free woks for chlorsulphonic acid, the derivatives of sulphonylcarbamid and benzolsulfocloramide
2222
“Pharmaceutical technology”Autumn term
Lectures.№ Mövzular Saat1 Solids: Powders as Dosage Forms. 22 Preparation of powders. 23 Liquid Dosage forms . 24 Galenicals. Preparation of water extractions.
Semisolid Dosages: Ointments and Liniments. 2
Topics.№ Mövzular Saat1 Solids: Powders as Dosage Forms. 22 Preparation of powders. 23 Liquid Dosage forms . 24 Galenicals. Preparation of water extractions.
Semisolid Dosages: Ointments and Liniments. 2Total 10 hours.
“Pharmaceutical technology”autumn semester
Practice.№ Mövzular Saat1 Solids: preparation of powders. 6h 2 Preparation of Species. 2h 3 Liquid Dosage Forms. Solvents. 6h4 Preparation of Concentrated and Standards Liquid Preparations.
Drops. 4h
5 HMS (high-molecular system) solutions. Colloid solutions. 4h6 Preparation of Suspensions and Emulsions. 4h7 Preparation of Water Extractions: Infusions and Decoctions. 6h8 Preparation of Mixtures. Mucilages. 4h9 Preparation of Ointments and Liniments. 8h10 Suppositories. Preparation of suppositories. 6h
54
Total: 50 h
The plan of lectures on pharmaceutical merchandizing (autumn term)
№ Themes Hours1 Introduction to pharmaceutical merchandizing. The emergence and
evolution of the pharmaceutical merchandising2
2 Quality of pharmaceutical products. Quality parameters. Requirements for pharmaceutical materials and goods. Safety and efficacy of medicines. Certification of the quality of medicines
2
3 Product policy in the field of pharmacy. Main areas of product policy. Assortment policy
2
4 Innovation policy in the field of a drugs creating. Steps for creating, conducting clinical trials, testing, and the legalization of modern medicines
2
5 Promotion of medicines. Advertising and information activities in the pharmacy. Basics of pharmaceutical information
2
6 Merchandising as the direction of drug promotion. Main methods of erchandising used in pharmaceutical field
2
7 Organization of marketing activities in the pharmaceuticals market 2
The plan of practical training on pharmaceutical merchandizing (autumn term)
№ Themes Hours1 Pharmaceutical products. Nomenclature. Types of classification of
pharmaceutical products. Basics of pharmaceutical terminology. Classification of medicines. Para pharmaceutical production
4
2 Merchandizing methods of pharmaceutical operations 33 Standardization of pharmaceutical products. The general concept
of standardization. International standards in the pharmacy (GMP, ISO). Pharmacopeia and pharmacopoeial articles. Normative and technical documents
4
4 Coding of pharmaceutical products. Modern methods of coding. Drugs anatomic-therapeutic-chemical system (ATC) classification. The coding system EAN
4
5 Packaging of pharmaceuticals. Requirements for packaging material. Types of packaging. Labeling of pharmaceutical products
3
6 Assortment of the pharmaceutical products. Parameters of an estimation of assortment. Methods for calculating the coefficient of completeness of the breadth and depth of assortment
4
7 The basic principles and rules for storage of pharmaceutical products
2
8 Stages of the life cycle of pharmaceutical products. Drawing a 4
55
graph that characterizes the life cycle of pharmaceutical products9 Types of information material used in the field of pharmacy.
Advertisements. Law of Azerbaijan Republic on medicines3
Pharmaceutical technology and administrationLectures
N Topic Hours
1. Basics of pharmaceutical service and principles of its organizationalstructure in Azerbaijan republic
2
2. Normative-legal base regulated pharmaceutical activity in Azerbaijan.
2
3. Licensing of pharmaceutical activity.System of provision of state control over pharmaceutical activity.
2
4. Notions of drugs quality, standardization and certification. Quality parameters
2
5. Drugs discovery and development on pharmaceutical market. Original and generic drugs
2
6. Organization of state control over quality of medicinal drugs. Drugs state registration
2
7. Organization of pharmacy as a discipline. Scientific-practical approaches and principles.Conception of pharmaceutical care: goals, objectives, forms
2
8. Types of pharmaceutical activity. Notions of retail selling. Particularities of activity of retail pharmaceutical organizations. GPP
2
9. Principles of merchandising, and its implementation in retail selling pharmaceutical institutions
2
10. Particularities of activity of wholesaling pharmaceutical companies, their classification and functions. GDP
2
11. Logistic system in pharmaceutical sector. Classification and types of logistics
2
12. Principles and functions of distribution in pharmaceutical industry. The role of information in drugs promotion
2
13. Organization of pharmaceutical care provision for in-patients. Formulary system
2
14. National Drug Policy and its directions. Problems of modern pharmacy
2
Total: 28 hoursPractice
N Topic Hours
56
1. The Law of Azerbaijan republic about Medicinal drugs. Essentials of terminology
4
2. Types of property in pharmaceutical sector. Organization-legal status of the institution, notions of physical and legal personality (normative-legal documents)
4
3. The guidelines of drugs’ (and other pharmaceutical production) state registration. The expertize procedure sequence. The Drugs State Register(normative-legal documents)
4
4. Retail pharmaceutical organizations: classification, functions, requirements. Sanitarian regimen. Labor protection and job safety (normative-legal documents)
6
5. Pharmacy staff. Employment agreement. Notions of material responsibility
4
6. Dispensing of OTC and prescription medicines. Rules of drugs’ prescribing. Pharmaceutical expertize (documents)
6
7. Organization of drugs compounding. In-pharmacy control. Dispensing and labeling of compounded medicines (documents)
4
8. Organization of preferential medicinal provision of special groups of patients (normative-legal documents)
2
9. Organization of controlled (regulated by government) drugs dispensing (narcotics, psychotropics, poisons). Subject-quantitative accounting(normative-legal documents)
4
10. The types ofpharmaceutical logistics. Logistic operations. Channels of drugs circulation
4
11. Organization of tender purchasing of medicinal drugs. Criteria of supplier selection. Contracting
4
12. Work organization in the pharmaceutical warehouse: tasks and functions.Normative requirements
4
13. Center of Innovation and drugs supply. The structure, tasks and functions
2
14. Organization of work and structureof hospital pharmacy. Rules and particularities of products’receiving and distribution
4
15. Center of Analytical expertize,its structure, tasks and functions. Inspection of pharmaceutical organizations (documents)
4
16. Pharmacovigilance and its implementation 2
Total: 76 hours
57
“Pharmaceutical economics” forspring term
Lectures
N Topic Hours
1. Introduction to pharmaceutical economics. Micro and macroeconomics. Pharmaceutical institution as the object of microeconomics
2
2. Classification and types of markets. Market relationships and competition. Particularities of pharmaceutical market
2
3. Economic resources of pharmaceutical organization (financial, tangible and intangible, information, human resources)
2
4. Accounting policy in pharmaceutical domain. Forms of accounting and accounting meters. Methods and elements of accounting
2
5. Accounting balance and its structure. Double-entry bookkeeping system. Actives and passives : assets, liabilities, equity
2
6. Planning and forecasting in pharmaceutical sector. Forms, methods and principles of planning
2
7. Marketing and its implementation to pharmaceutical practice. Marketing mix
2
8. Pharmacoeconomics. Principles and terms of pharmacoeconomic studies
2
Total: 16 hoursPractice
N Topic Hours
1. Notions of essential laws of economics. Demand, supply, and factors affecting on them (price and non-price determinants). Market equilibrium. Evaluation of pharmaceutical products’ price elasticity (calculation)
6
2. Consumer behavior on pharmaceutical market. Approaches to formation of consumers’ preferences. Budget line. Construction of the budget curve
6
3. Price and its functions. Pricing principles and strategy. Particularities of pricing for medicinal drugs. Normative documents regulated pricing (documents of tariff committee)
6
4. Methods and elements of accounting. Measurement, calculation, evaluation etc. Accounting documentation. Chart of accounts. Recording and analysis of transactions (examples)
6
5. Preparation and structure of accounting balance. Preparation of accounting reports (Financial statements). Balance sheet(work with accounting documents)
6
58
6. Classification of assets. Accounting of fixed assets. Methods and rules of depreciation (amortization). Calculation of depreciation expense
6
7. Accounting of current assets in pharmaceutical institution. Accounting of turnover. Purchasing and supplying operations
6
8. Structure and classification of inventory. Inventory management. Methods of inventory planning
4
9. Mark-up. Accounting and planning of mark-up. Expenses of circulation: fixed and variable. Accounting and planning of expenses (examples)
4
10. Accounting of cash. Cashbox operations. Cash inflow and outflow. Cash basis and accrual basis accounting (work with accounting documents)
6
11. Types and forms of labor compensation (wages and salary). Labor accounting (examples)
4
12. Main economic indicators of pharmaceutical company. Methods of estimation and prediction of economic indicators. Analysis and planning of margin (gross profit and net profit). Profitability. Calculation of profitability and other financial ratios (examples)
6
13. Business-plan preparation. Its role in pharmaceutical practice. Structure andfunctionsof business-plan
2
14. System and directions of pharmaceutical marketing researches.Basic marketing tools. Market segmentation. Pharmaceutical marketing strategy
6
Total: 74 hours
The plan of lectures on “Pharmacology” (autumn term)N Themes Hours
1 Introduction. History of development. Concept about General pharmacology. Pharmacology of drugs affecting Afferent innervation. 2
2 Pharmacology of drugs affecting Efferent innervation: Cholinergic and Adrenergic system. 2
3 Pharmacology of drugs affecting CNS: General anesthetics, Ethanol, Hypnotics, Antiepileptic, Antiparkin-sonian drugs, and Analgetics. 2
4Psychotrop drugs (I lecture): Pharmacology of Neuroleptics, Tranquilizers, Sedativ drugs, and Lithium Salt. Concept about Psychodisleptics.
2
5 Psychotrop drugs (II lecture): Pharmacology of Psymotor stimulants, Antidepressants, Nootrop drugs, and Analeptics. 2
The plan of practical training on “Pharmacology” (autumn term)N Themes Hours1. Pharmacology as Subject, aim and tasks. Introduction to General 2
59
Prescription. Structure of Prescription, rules of writing out of Prescription. Drug form conception.
2. Information about Hard drug forms. Visual demonstration and rules of writing out of Hard drug forms. 2
3. Rules of writing out of Hard drug forms (continuation). 24. Information about Soft drug forms. Visual demonstration and rules of
writing out of Soft drug forms. 2
5. Rules of writing out of Soft drug forms (continuation). 26. Information about Liquid and different drug forms. Visual demonstration
and rules of writing out of Liquid and different drug forms. 2
7. Rules of writing out of Liquid and different drug forms (continuation). 28. Different drug forms. Its visual demonstration and rules of writing out. 29. Final lesson: General Prescription 210.General Pharmacology. Drugs Pharmacokinetics and Pharmacodynamics. 211.Pharmacology of Drugs affecting the Afferent System (Experimental
work). 2
12. Information about Efferent System. Bases pharmacological properties of Drugs affecting the Cholinergic Innervation. M-,N-cholinomimetics, M-,N-cholinoblockers and Anticholinesterase Drugs (Experimental work).
2
13.Bases pharmacological properties and clinical application of M-cholinomimetics and M-cholinoblockers. 2
14.Bases pharmacological properties and clinical application of N-cholinomimetics and N-cholinoblockers (Experimental work). 2
15.Adrenergic System conception. Bases pharmacological properties of Drugs affecting the Adrenergic System. Pharmacology of Directly Adrenomimetics (α, β; α and β) and Sympathomimetics (Experimental work).
2
16.Bases pharmacological properties of adrenoblockers (α, β; α and β) and sympatholytics. 2
17.Final lesson: General Pharmacology, Drugs affecting the Afferent and Efferent Innervation. 2
18.Bases pharmacological properties of Drugs affecting the Central Nervous System. Pharmacology of General anesthetics. (Experimental work) 2
19.Pharmacology of Ethanol and Hypnotic Drugs. General and particular principles of Alcoholism pharmacotherapy. 2
20.Analgesic Drugs. Pharmacological properties and clinical application of Opioid and Nonopioid Analgesic. Opioid Analgesic Acute and Chronic Poisoning. General and particular principles of Narcomania pharmacotherapy
2
21.Pharmacology of Antiepileptic and Antiparkinsonic Drugs. 2
60
22.Obtainment and Clinical application of Psychotropic Drugs. Pharmacology of Antipsychotic Drugs (Experimental work). 2
23.Pharmacology of Antidepressant, Anxiolytic, Sedative Drugs and Lithium Salts (Experimental work). 2
24.Pharmacology of CNS Stimulant Drugs (Psychomotor Stimulants, Analeptics) Drugs affecting the GABA – Nootrop Drugs. General information about Psychodisleptics. (Experimental work).
2
25.Final lesson: Drugs affecting the CNS 2
The plan of lectures on “Pharmacology” (spring term)
N Themes Hours1 Pharmacology of drugs affecting the cardiovascular system. 22 Pharmacology of drugs affecting the function of digestive organs. 23 Pharmacoligy of drugs affecting the blood system. 24 Pharmacology of hormonal drugs and anabolic steoids. 25 Pharmacology of drugs affecting inflammation and immune processes.
(NSAID, antiallergic drugs, immunostimulators) 2
6 Pharmacology of antiseptic-disinfectants and antibiotics. 27 Pharmacology of sulfonamides and synthetic antibacterial agents of various
chemical structures. Pharmacology of drugs used to treat tuberculosis, syphilis and leprosy. Antifungal and antiviral drugs.
2
The plan of practical training on “Pharmacology” (spring term)
N Themes Hours1. Pharmacology of Drugs affecting the Respiratory System. 22. Pharmacology of Drugs affecting the Cardiovascular System:
cardiotonics. Antiarrhythmic Drugs 2
3. Pharmacology of Drugs affecting coronary flow (angina, myocardial infarction). Pharmacology of Hypo- and Hypertensive Drugs. Diuretics 2
4. Pharmacology of Drugs affecting the Gastrointestinal Tract. 25. Pharmacology of Drugs affecting the Haemopoietic System.
Pharmacology of Drugs affecting the physiological mechanism of Coagulation.
2
6. Final lesson: Drugs affecting major organ systems. 27. Pharmacology of Hormones. Anabolic steroids. Pharmacology of Drugs
affecting uterus. Drugs used for contraception. 2
8. Pharmacology of Vitamins. Pharmacology of enzymes, aminoacides and parenteral nutrition. Pharmacology of Drugs affecting acid-base balance, ion metabolism, plasma substitutes, detoxication solutions, solutions for
2
61
replacement of synovial fluid and lachrymal liquors.9. Pharmacology of Hypolipedimic drugs. Antigout drugs. Pharmacology of
Drugs affecting cerebral circulation, antihypoxants, antioxydants, angioprotectors.
2
10.Pharmacology of Non-Steroidal Anti-inflammatory Drugs. Pharmacology of Antiallergic Drugs. Immunostimulant Drugs. 2
11.Final lesson: Drugs affecting metabolic processes. 212.Pharmacology of Antiseptic Drugs, disinfectants and antibiotics 213.Pharmacology of Sulfonamides and difference chemical groups of
Synthetic Antimicrobials. Pharmacology of Antituberculosis, Antisyphilitics and Antileprosy Drugs. Pharmacology of Antiviral and Antifungal Drugs
2
14.Pharmacology of Drugs used in pediculosis and Scabies. Anthelmintics. Pharmacology of Antiprotozoal Drugs. Pharmacology of drugs used in the cancer chemotherapy.
2
15.Final lesson: Drugs affecting the organs and Antimicrobial, Antiviral, Antifungal, Anthelmintic and Antiprotozoal Drugs. 2
16.Final lesson for material of VI semester 2
IV course
The Theme Plan of the Laboratory Classes on “Pharmocognosy- 3” for autumn term
№№ Topics of the laboratory classes Hours
1 31. The medicinal plants and raw materials that
inside alkaloids.1.Belladonna leaves2. Henbane leaves3. Datura leaves4. Scopolia5. Hatched-vetch6. Bush-pea
4
2. 1. Strychnine tree2. Ergot3. Passionflower herb4. Rauvolfia root5. Catharanthus herb
4
3. 1. Killwort herb2. Barberry roots and leaves 3. Stephania root-tuber
4
62
4. Senecio rhizomes and herb5. Colchicines6. Nightshade
4. Thea leaves Carsicum fruits Ephedra herbHarmala herbYellow-pound-lily Tulip poppy Fir clubmoss
Sphaerophysa herb Anabasis herb Quinine bark Siberian Pachycarpa herbOpium fruitsCoca leavesCarex herb
4
5. Meadow rue herbGlobe thistle fruitCoffea seedAkonit root-tuber
Milkvetch rhizome and roots
4
6. Analysis of alkaloids. Carrying of sedimentary and color reactions to alkaloids.
4
7. Raw materials of animal origin. The products of bee vital functions (honey, propolis, pollen, royal jelly, bee venom, beeswax). Fresh-water sponge. Leeches. Fats of animal origin. Raw materials of mineral origin: shilajit
4
8. The medicinal plants and raw material containing Phytoecdistreoids.Maralroot rhizome with root
Medicinal plants using as the food supplement. 1. Chinese cinnamon 2. Turmeric 3. Ginzer 4. Saffron crocus 5. Clove
4
63
6. Cardamom
9. The standardization of themedicinal plant raw material. Analytical documentation on the medicinal plant raw material. Acceptance of the medicinal plant raw material. Merchandising analysis
4
10. Conclusion lesson. 1
The theme plan of the lectures on “Pharmacognosy- 3” autumn term
№ The topic of the lecture Hours
1 Alkaloids Chemical structure, classification, phisico-chemical properties, spreading in the plants, the accumulation and role in plant. The role Azerbaijan and foreign scientists in investigation of medical plants, containing alkaloids. Features of the structure of steroidal alkaloids, and the prospect of their use for the synthesis of steroid drugs.
2
2 The medicinal raw materials of animal and mineral origin .The snake poison; bee products of vital functions (honey, propolis, pollen, bee venom, and others. Fresh-Water sponge. Leeches. Antlers Aquatic organisms (hydrobionts).
2
3 The medicinal plants and raw material containing phytoecdistreoids. The medicinal plants using as the food supplement.The ways methods of identification and research of new medicinal plants . Analytical documentation on the medicinal plants .
2
4 Introduction of the medicinal plants. Culture of the isolated tissues and cells.Determination of the resource of the medicinal raw materials. Harvesting, storage and rational usage of them.Protection actions.
2
64
The theme plan of the lectures on “Pharmacognosy- 3” autumn term
№ The topic of the lecture Hours
1 Alkaloids Chemical structure, classification, phisico-chemical properties, spreading in the plants, the accumulation and role in plant. The role Azerbaijan and foreign scientists in investigation of medical plants, containing alkaloids. Features of the structure of steroidal alkaloids, and the prospect of their use for the synthesis of steroid drugs.
2
2 The medicinal raw materials of animal and mineral origin .The snake poison; bee products of vital functions (honey, propolis, pollen, bee venom, and others. Fresh-Water sponge. Leeches. Antlers Aquatic organisms (hydrobionts).
2
3 The medicinal plants and raw material containing phytoecdistreoids. The medicinal plants using as the food supplement.The ways methods of identification and research of new medicinal plants . Analytical documentation on the medicinal plants .
2
4 Introduction of the medicinal plants. Culture of the isolated tissues and cells.Determination of the resource of the medicinal raw materials. Harvesting, storage and rational usage of them.Protection actions.
2
The Theme Plan of the Laboratory Classes on “Pharmocognosy- 3” for autumn term
№№ Topics of the laboratory classes Hours
1 31. The medicinal plants and raw 4
65
materials that inside alkaloids.1.Belladonna leaves2. Henbane leaves3. Datura leaves4. Scopolia5. Hatched-vetch6. Bush-pea
2. 1. Strychnine tree2. Ergot3. Passionflower herb4. Rauvolfia root5. Catharanthus herb
4
3. 1. Killwort herb2. Barberry roots and leaves 3. Stephania root-tuber4. Senecio rhizomes and herb5. Colchicines6. Nightshade
4
4. Thea leaves Carsicum fruits Ephedra herbHarmala herbYellow-pound-lily Tulip poppy Fir clubmoss
Sphaerophysa herb Anabasis herb Quinine bark Siberian Pachycarpa herbOpium fruitsCoca leavesCarex herb
4
5. Meadow rue herbGlobe thistle fruitCoffea seedAkonit root-tuber
Milkvetch rhizome and roots
4
6. Analysis of alkaloids. Carrying of sedimentary and color reactions to alkaloids.
4
66
7. Raw materials of animal origin. The products of bee vital functions (honey, propolis, pollen, royal jelly, bee venom, beeswax). Fresh-water sponge. Leeches. Fats of animal origin. Raw materials of mineral origin: shilajit
4
8. The medicinal plants and raw material containing Phytoecdistreoids.Maralroot rhizome with root
Medicinal plants using as the food supplement. 1. Chinese cinnamon 2. Turmeric 3. Ginzer 4. Saffron crocus 5. Clove 6. Cardamom
4
9. The standardization of themedicinal plant raw material. Analytical documentation on the medicinal plant raw material. Acceptance of the medicinal plant raw material. Merchandising analysis
4
10. Conclusion lesson. 1
The Calendar-Subject Plan of the Laboratory Classes on Phytotherapy for spring term
N Laboratory practice topics Hour
1
The concept of Phytotherapy. The history of Phytotherapy , pharmaceutical and information base, rule and principles, relation to another medical subjects, the importance for medicine.The concept of the Herbal remedies.Basic rules of the determining of medicinal plants in Phytotherapy.
2
67
2
The modern condition of Phytotherapy and development of its various directions (biological supplements, aromatherapy, therapeutic enema, treatment procedure , etc.). The essence of Phytopharmacology. The influential properties of biologically active substances. The aggravation and adverse impacts related to Phytotherapy.
2
3 Medicinal plants and herbal medicines used in treatment of Nervous System disorders. 2
4 Medicinal plants and herbal medicines used in treatment of Gastrointestinal System disorders. 2
5 Herbal remedies used in treatment of Cardiovascularsystem disorders.
2
6 Herbal remedies used in treatment of Respiratory system diseases. 2
7 Herbal remedies used in treatment Liver and Gallbladder diseases. 2
8Phytotherapy of immunodeficiency disorders.Medicinal plants and herbal medicines having immunomodulator features.
2
9 Medicinal plants and herbal medicines used for treatment of hormonal and endocrinology diseases. 2
10Herbal remedies used for treatment and prophylaxis of gynaecological diseases.The Phytotherapy of the precancerous conditions in women .
2
11 The herbal remedies used in urology and nephrology. 2
12The Phytotherapy of the rheumatic diseases. The importance of the phytotherapeutic remedies in the medicinal removal of toxic substance from the human body (detoxification).
2
13 Herbal remedies used treatment for skin diseases in cosmetology. 2
14The Phytotherapy of the diseases of the pharynx, mucous membrane, oral cavity.The use of herbal remedies in dentistry and ophthalmology.
2
68
15Herbal remedies used to treat different diseases ( oncological, anaemia, drug addiction , phytotherapy of aging, alcoholism and e.t.c ).Conclusion lesson
2
The plan of practical training on pharmaceutical chemistry-3
N(autumn term)
Themes Hours
1 Analysis of medicine preparations of furan and 5-nitrofuran derivatives (nitrofural – substance, furazolidone – tablets).Free work: the derivatives of 5-nitrofuran and benzofuran.
6+6
2 Analysis of medicine preparations of coumarin and chroman derivatives (neodicumarinum – tablets, carbocromen – tablets).Free work: derivatives of benzopyrane, coumarin and chroman derivatives.
6+6
3 Analysis of medicine preparations of phenylchroman derivatives (rutoside – substance, quercetinum).Free work: phenylchroman derivatives and benzo-1,4-dioxane. Control work: to lectures 1-3.
6
4 Analysis of medicine preparations of pyrrole and pirrolizidine derivatives (piracetam – tablets, cyanocobalamin – solution for injection). Free work: pyrrole derivatives and its condensation system.
6+6
5 Analysis of medicine preparations of indole derivatives (reserpine – tablets, securinine-nitrate - tablets, proserinum – solution for injection, strychnine-nitrate – solution for injection).
6+6
6 Analysis of medicine preparations of pyrazole derivatives (metamizole sodium - tablets, phenylbutazone - substance).Free work: pyrazole derivatives.
6
7 Analysis of medicine preparations of imidazole (bendazole hydrochloride – substance; solution for injection, metronidazole – tablets). Free work: imidazole and sydnonimine derivatives. Control work: to lectures 3-5.
6
8 Analysis of medicine preparations of pyridine and pyridine-3-carbonic acid (pyridoxine hydrochloride – substance, solution for injection, parmidine - tablets,
6+6
69
nicotinic acid - substance, nicodinum - tablets). Free work: pyridinemethanol and pyridine-3-carbonic acid derivatives.
9 Analysis of medicine preparations of pyridine-4-carbonic acid (isoniazid – tablets, phthivazidum – substance, niphedipine – tablets). Free work: pyridine-4-carbonic acid and pyridine-3,5-carbonic acid derivatives.
6
10 Analysis of medicine preparations of tropane (atropine sulphate – solution for injection, tropacine – substance).Free work: tropane derivatives. Control work: to lectures 8 and 9.
4
The plan of lectures training on pharmaceutical chemistry-3
N(autumn term)
Themes Hours
1 Natural and synthetic heterocyclic compounds. Derivatives of furan, 5-nitrofuran and benzofuran.
2
2 Derivatives of benzopyrane. Coumarins and their derivatives. The derivatives of chroman and phenylchroman. The derivatives of benzo-1,4-dioxane
2
3 The nitrogen heterocycles. Derivatives of pyrrole and its
condensation system. 2
4 Derivatives of indole. Serotonin, yohimbine, lizerginic acid and
derivatives of eozeroline. 2
5 Derivatives of pyrazole. 2
6 Derivatives of imidazole and sydnonimine. 2 7 Derivatives of pyridine and tropane derivatives. 2
The plan of lectures on pharmaceutical chemistry-4
(spring term)
N Themes Hours
1.Quinoline and quinuclidine derivatives. Quinoline derivatives. The synthetic analogues of 4-replacement and 8-replacement quinoline derivatives as synthetic analogues. Quinolon -4 derivatives.Quinuclidine derivatives.Izoquinoline derivatives. Benzylisoquinoline derivatives. Phenantrenizoquinoline derivatives. Morphine, codeine alkaloids
2
70
and its’ preparations. Aporphine derivatives.
2.
Piperazine and pyrimidine derivatives. Piperazine derivatives. Pyrimidine-2,4-dion derivatives. Citostatic and antivirus action preparations as pyrimidine nucleosides.The derivatives of pyrimidine-2,4,6-trion (barbiturates). Pyrimidine-thiazol derivatives. B1 group vitamins. The role of studing of metabolism of thiamine in organism for creation coenzyme preparations. Cocarboxylase, phosphothiamine, benfotiamine.
2
3. Purin derivatives. Xanthine derivatives. Purin nucleosides. Antimetabolit nature preparations as purine derivatives. 2
4.Pteridine and isoalloxazine derivatives.Folic acid and its analogues.Derivatives of phenothiazine. Alkylamine derivatives of phenothiazine. Acylderivatives of phenothiazine
2
5.Azepine, benzodiazepine and oxazine derivatives. Аzepine derivatives. Benzodiazepine derivatives. Dibenzodiazepine derivatives. Оxazine derivatives.
2
The plan of practical training on pharmaceutical chemistry-4 (spring term)
N Themes Hours1 Analysis of medicine preparations of quinoline and quinuclidine
derivatives: quinine sulphate and nitroxoline (5-NOK) .Carring out of test-tasks and free works for quinolin and quinuclidin derivatives .
8
2 Analysis of medicine preparations of izoquinoline derivativers: papaverine hydrochloride, glaucini hydrochloridum and drotaverine hydrochloride (Nospanum), medicine forms .Carring out of test-tasks and free works for isoquinolin derivatives.
6
3 Analysis of medicine preparations of pirimidine-2,4,6-trions (barbituric acid) derivativers: barbital, phenobarbital, barbamil, hexamidin and barbital sodium.Carring out of test-tasks and free works for pirimidine-2,4,6-trions (barbituric acid) derivatives .
6
4 Analysis of medicine preparations of pirimidine-thiazole derivatives (B1 group vitamins): thiamine hedrochloride, cocarboxylase and benfothiamine and medicine forms.Carring out of test-tasks and free works for pirimidine-thiasol derivatives.
6
5 Analysis of purine derivatives preparations: caffeine, caffeine-sodium benzoate, theophylline, theobromine and euphylline and its medicine forms. Carring out of test-tasks and free works for purine derivatives.
6
6 Analysis of pteridine and isoalloxazine derivatives preparations: folic acid and riboflavine and medicine forms.Carring out of test-tasks and free works for pteridine and
6
71
isoalloxazine derivatives7 Analysis of preparations of phenothiazine derivatives: aminazinum
and nozepam medicine forms. Carring out of test-tasks and free works for phenothiazine derivatives
6
8 Analysis of preparations of benzodiazepine derivatives: Carring out of test-tasks and free works for benzodiazepine derivatives
6
The plan of lectures on pharmaceutical technology (spring term)
№ Themes Hours1 Solid pharmaceutical forms, classification, characteristics. Tablet
technology4
2 Medical capsules and microcapsules manufacturing technology 43 Soft drug forms technology 24 Prepared under aseptic conditions and technology of sterile
pharmaceutical forms2
5 Technology of eye drug forms 26 New pharmaceutical forms, biopharmaceutical properties 27 Medical aerosols technology 2
The plan of seminar on pharmaceutical technology (spring term)
№ Themes Hours1 Tablets, active substances and excipients their features 82 Tablet manufacturing technology 83 Manufacturing technology of medical capsules 84 Manufacturing technology of microcapsules 85 Manufacturing technology of ointments, liniments, gels, pastes 86 Manufacturing technology of candles. Manufacturing
technology of medical pencils and plastırs8
7 Manufacturing technology of injection solutions 88 Manufacturing technology of eye drug forms 89 Manufacturing technology of the modern herbal forms 8
“Biopharmaceutics Foundations”
autumn term
Practice:№ Mövzular Saat1 Biopharmaceutics and its role in pharmaceutical technology. 22 Basic conceptions of Biopharmaceutics. 23 Physical state of drug substance. 24 Simple chemical modification of drug substance. 2
72
5 Excipients and their natire and quantity. 26 Manufacturing parameters characteristic. 27 Applications of drug forms. 28 Individual state of patient (physiological status, feeding, half life,
changing factors biorhythm etc.). 4
9 Bioavailability of drugs and methods of determination. 410 LADME system in biopharmaceutics 211 Biopharmaceutics of tablets. 412 Biopharmaceutics of ointments. 2
Total: 30 hours “Pharmaceutical management”
fall termPractice
№ Mövzular Saat1 Notions of management. Management theory and its development.
Scientific schools of management. 4
2 Methods of administration. Essential principles and functionsof management. Motivation. The process of management(H.Fayol)
4
3 Leadership as the principle of management. Character and types ofleadership. 2
4 Particularities of management of pharmaceutical organizations: Goals and objectives. Organization’s life cycle. Internal and externalenvironment of pharmaceutical organization.
4
5 The structure of pharmaceutical organization. Departmentalization: Principles of systematization in management. 4
6 HR Management in pharmaceutical organizations: aspects and functions. 4
7 The basic concept of administration: decision making process.Principles of labor division in pharmaceuticalorganization
2
8 Communication within pharmaceutical organization. Formal and in-formal groups. 2
9 Conflicts and main principles of conflict management. 2
10 The basics of recordkeeping (office work) in pharmaceutical organization 2
Total: 30 hours
The plan of practical training on pharmaceutical biotechnology and
biopharmacy (autumn term)
№ Themes Hours1 Biopharmacy and effectiveness of the drug means 2
73
2 Pharmaceutical factors influence on therapeutic effectiveness of drugs
2
3 Chemical modification and physical form of substances. Auxiliary substances and drug form
4
4 Bioavailability of drugs and methods of their determination 25 Technological operations 26 Pharmacokinetic and pharmacodynamics of the drug substances 47 Drug improvement problems and new pharmaceutical technologies 48 Biotechnology. GLP, GMP, GGP – standards 29 Principles of bioethics for biotechnology manufacturing 210 Improvements of traditional drugs: antibiotics, vitamins, hormones,
ferments and immunobiopreparations 2
11 Technologies of new biotechnological drugs: therapeutic systems. Control and management principles of biotechnological operations
4
The plan of lecture on Clinical Pharmacology
N Themes Hours1 Main principles of clinical pharmacology, Pharmacodynamics,
pharmacokinetics2
2 Adverse drug reactions, drug interactions. 23 Drug in pregnant and breast feeding women
Influence of disease and age on pharmacokinetics and Pharmacodynamics
2
4 Pharmacotherapy of cardiovasculyar drugs (I part) 25 Pharmacotherapy of cardiovasculyar drugs(II part) 26 Clinical pharmacotherapy of bronchoobstruction syndroms 27 Main principles of pharmacoprhetrapy of gastrointestinal
disorders2
The plan of practical training on Clinical Pharmacology
N Themes Hours1 Main principles of clinical pharmacology of cardiovascular
drugs5
2 Cardiovasculyar drugs; antianginal and antiarrhythmias drugs
5
3 Clinical pharmacology of drugs used for treatment of bronchoobstructive syndrom
5
4 The basis of rational pharmacotherapy. Clinical pharmacology of antibacterial agent
5
5 Clinical pharmacology of drugs used for gastrointestinal 5
74
Disorders6 Clinical pharmacology of drugs used for gastrointestinal
Disorders5
7 Clinical pharmacology of antiinflamation drugs 58 Clinical pharmacology of drugs used in urgent situations in
the clinic of internal diseases5
9 Clinical pharmacology of drugs acting on the system of hemostasis
5
10 Clinical pharmacology of drugs used in endocrine disorders 5
The plan of lectures on microbiology and immunology autumn term
N Topics Hours1 Medical microbiology and immunology, its objects.
Morphology, structure, classification and taxonomy of microorganisms. The role of microbiology in pharmaceutist practical activities
2
2 Physiology, nutrition, metabolism, multiplication of microorganisms. Genetic of microorganisms. The fundamentals of biotechnology
2
3 Action of physical, chemical and biological factors on microorganisms. Bacteriophages. Antibiotics. Chemotherapeutic agents. The fundamentals of chemotherapy
2
4 Microflora of environment. Microflora of medicinal preparations
2
5 Infection and infectious process. Virulence factors of microorganisms
2
6 Immunity, its functions. Non-specific protection factors of host 27 Specific (acquired) immunity. Antigens, antigenic structure of
microbial cell. Antibodies, immunoglobulins, its classes2
8 Immunotherapy and immunoprevention. The vaccine and antiserum
1
The plan of practical training on microbiology and immunology autumn term
N Topics Hours1 Microbiology laboratory. The methods of microbiology
investigation. Microscopes. The working manner with microscopes
2
75
2 Microscopic method. Smears preparation. Morphology and classification of bacteria. The simple stain. Gram stains
2
3 Structure of bacterial cell. Neisser, Ziehl Neelsen and spore stains 24 Structure of bacterial cell. Gins-Burry stain. Investigation of
bacterial motility2
5 Morphology and classification of Spirochetes, Rickettsiae, Chlamydia, Mycoplasma and Actinomyces (Giemsa stain)
2
6 Morphology and classification of fungi, protozoa and viruses 27 Conclusion lesson 28 Nutrition, respiration and multiplication of microorganisms,
nutrition media. Action of physical and chemical factors on microorganisms. Sterilization and disinfection
2
9 Bacteriological method. Isolation of the pure culture of aerobes and anaerobes (the first day)
2
10 Isolation of the pure culture of aerobes and anaerobe (the second day). Cultural character of microorganisms
2
11 Isolation of the pure culture (the third day). Biochemical character of microorganisms
2
12 Obtaining and classification of antibiotics. Chemotherapeutic agents. Antibiotic sensitivity tests
2
13 Bacteriophages. Obtaining and studying of bacteriophages 214 Microbiological investigation of medicinal preparations 215 Conclusion lesson 2
The plan of lectures on microbiology and immunology spring term
N Topics Hours1 Introduction to basic microbiology. The causative agents of
inflammatory diseases (pathogenic cocci and opportunistic bacteria). Pathogenic anaerobes
2
2 The causative agents of intestinal and zoonotic infections 23 Genus Haemophilus, Bordetella, Legionella, Corynebacterium,
Mycobacterium and Actinomyces2
4 Pathogenic Spirochetes, Rickettsiae, Chlamydiae and Mycoplasma 25 Pathogenic fungi and protozoa 26 Introduction to basic virology. The causative agents of respiratory
viral infections (orthomyxoviruses and paramyxoviruses). Herpes viruses, picornaviruses and rhabdviruses
2
7 Hepatitis viruses. Human immunodeficiency viruses 2
The plan of practical training on microbiology and immunology spring term
N Topics Hours1 The main principles of microbiology diagnosis of infection
diseases. Microbiology diagnosis of diseases, caused by 2
76
staphylococci2 Microbiology diagnosis of diseases, caused by streptococci 23 Microbiology diagnosis of diseases, caused by pathogenic
Neisseria2
4 Microbiology diagnosis of diseases, caused by opportunistic bacteria (Klebsiella, Proteus, Pseudomonas aeruginosa)
2
5 Microbiology diagnosis of diseases caused by Escherichia coli and Salmonella
2
6 Microbiology diagnosis of dysentery and cholera 27 Microbiology diagnosis of zoonotic infections (plague and
tularemia)2
8 Microbiology diagnosis of zoonotic infections (brucellosis and anthrax)
2
9 Microbiology diagnosis of diseases, caused by anaerobes (genus Clostridium and Bacteroides)
2
10 Microbiology diagnosis of diseases, caused by Haemophilus and Legionella
2
11 Microbiology diagnosis diphtheria and whooping coogh 212 Microbiology diagnosis tuberculosis and actinomycosis 213 Microbiology diagnosis of diseases, caused by Spirochetes14 Microbiology diagnosis of diseases, caused by Rickettsiae,
Chlamydiae and Mycoplasma2
15 Conclusion lesson 216 Microbiology diagnosis of mycosis 217 Microbiology diagnosis of parasitic infection 218 Introduction to basic virology. Microbiology diagnosis of
respiratory viral infection (influenza, parainfluenza, respiratory synsytial and adenovirus infections)
2
19 Microbiology diagnosis of child’s respiratory viral infection (mumps, measles, varicella, rubella)
2
20 Microbiology diagnosis of infections, caused by herpes viruses and enteroviruses
2
21 Microbiology diagnosis of viral hepatitis 222 Microbiology diagnosis of Acquired Immunodeficiency
Syndrome (AIDS)2
23 Conclusion lesson 2
Program of lectures of Pathophysiology (Autumn term)
№ Subject Hours
1. Introduction. The subject of pathophysiology. Evolution of 2
77
pathophysiology. An idea of “general nosology”.
2. Pathogenic role of the external and internal factors in pathology. 2
3. Reactivity. Pathology of immune system. Allergy. 2
4. Cell injury. Pathology of microcirculation. Local circulatory disorders. Inflammation. Fever. 2
5. Pathology of metabolism. Pathology of tissue growth. Extreme states.
2
Program of practical lessons of Pathophysiology autumn term
№ Theme of practical study
Parts of practical study Hours
1. Introduction. Significance of experimental method in pathophysiological researches. General etiology and pathogenesis. Pathogenic influence of environment.
1.The methods and tasks of pathophysiology. Etiology and pathogenesis.2.Determination of terms: norm , health, disease.3.Disease: classification, stages , causes, outcome.4.Classification of external factors, their role in the development of disease5.Influence of the high and low temperature on the organism.
4
2.The role of hereditary and constitution in pathology.
1.Etiology and pathogenesis of hereditary disease.2.Types of hereditary diseases, methods of their investigation and treatment.3.Types of constitutions, diatheses.4.Determination of sex chromatin.
4
3.
Role of the reactivity in pathology.
1.An idea of reactivity of the organism. Classification of the reactivity (А.Д. Аdo)2.Resistance of organism. Interrelation of reactivity with internal and external factors.3.Immunity.Immune reactivity.4. Influence of dizenterine vaccine on reactivity.
4
4. Pathology of immune system. Allergy.
1.Immune deficiency syndromes.2.Allergy. Types and classification of allergic reactions.3.Allergens: classification and characteristics.4.Types and of allergic reactions
4
78
5. Anti-allergic therapy.6.Reproduction of anaphylactic shock.
Quiz The final seminar that includes previously studied themes: “General nosology”, «Hereditary», «Reactivity», «Immunity, Allergy».
5.
Pathological physiology of cell.
1.Types of cell injury. 2. Specific and non-specific mechanisms of cell injury.3.Protective reactions against of cell injury.4. Alteration of mucosa membrane of oral cavity of frog.
4
6.
Disorders of microcirculation and local circulation.
1.Pathology of microcirculation2.Arterial hyperemia, etiology, pathogenesis, venous hyperemia, etiology, pathogenesis.3.Ischemia, stasis, infarction, thrombosis and embolism.4.Reproduction of ischemia, stasis, infarction, thrombosis and embolism.
4
7.
Inflammation.
1.Inflammation. Theories of inflammation 2.Causes, stages and outcome of inflammation.Classification of inflammation.3.Principles of pharmacological correction.4.Cohnheim’s experiment.
4
8.
Fever.
1. Etiology, pathogenesis, stages, significance of fever.2.The role of endocrine and nervous system in the development of fever.3.The types of temperature curves 4.Common and different futures of fever and hyperthermia . 5Influence of fever on ESR and number of leukocytes 6. Principles of pharmacological correction.
4
Quiz
The final seminar that includes previously studied themes: “Cell injury», «Pathology of microcirculation and local circulation” «Inflammation», «Fever»
9.Pathology of metabolism.
1.General characteristic of metabolism .2. Disorders of carbohydrate, protein and lipid metabolism.3. Reproduction of diabetes mellitus
4
10. Pathology of metabolism..
1. Disorders of water-salt metabolism.2. Disorders of mineral metabolism . 3. Disorders of vitamin metabolism.
4
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4. Disorders of acid-alkaline balance. 5. Starvation.6. Reproduction of edemas.
11. Pathology of the tissue growth. Tumors.
1. Hyper- and hypobiotical processes 2. Tumor. Etiology, pathogenesis3. Reproduction of dezoxidative carbonuria
4
12.
Pathological physiology of extreme states.
1.Extreme states: causes, types, characteristic.2.Causes and mechanisms of shock..3.Collapse: syncope, coma: types, causes, mechanisms of development.4.Stress5.Hypoxia. 6.Reproduction of hypoxia on experiment.
4
QuizThe final seminar that includes previously studied themes: «Pathology of metabolism.», «Tumor», «Pathological physiology of extreme states»
13. Final 2
Program of lectures of Pathophysiology (Spring term)
№ Subject Hours1 Pathology of Blood System 2
2 Pathology of Blood Circulation and Respiration 2
3 Pathology of Digestion and Liver 2
4 Pathology of Renal Function 2
5 Pathology of Endocrine regulation and Nervous system 2
Program of Practical lessons of Pathophysiology (Spring term)
№ Subject Hours1 Blood System Pathology.
a) reproduction of the hemolytic anemia in rabbits.b) determination of activity of catalase and the number of erythrocytes in
anemiac) reproduction of the leukocytosis and leucopenia in rabbit.
Microscopic examination of blood smears of the patients with leucosis
4
80
2 Pathology of Blood Circulation.a) Reproduction of Stenocardia in Rabbits by the Pituitrin Injection.b) Etioilogy and Pathogenesis of Ischemic Heart Diseasec) Reproduction of the Experimental Heart Block in Frog.d) Mechanisms of development of Neutrogenic hypertension
4
3 Pathology of Respiration.a) Reproduction of the Periodic Breathing in Frog. b) Reproduction of the Reflex Apnea in Experiment. I quiz
4
4 Pathology of Digestion. a) Examination of Gastric Juice Acidity in experimental stomach ulcer.
Microscopic Examination of Gastric Juice. b) Pathology of Digestion. Disturbances of intestinal functions.
4
5 Hepatic Function Pathology. a) Toxic Effect of Bile on the Organism.b) Analysis of conjugated and un conjugated bilirubin.
4
6 Renal Function Pathology. a) Physico-chemical Analysis of Urine in Nephritis. b) Microscopic Examination of urine in Nephrosis.
II quiz
4
7 Pathology of the Endocrine Regulation.a) Reaction of Hypophysadrenal System to the injured influence of
electric current. b) Influence of Parathyroidectomy on Blood Ca Level.c) Studying of the General Changes of Thyroid Gland Hyper and Hypo
Functions.
4
8 Pathology of the Nervous System. a) Reproduction of Camphor Epilepsy.b) Influence of Dissection of the Motor Nerves on the Reflexes of Frog. c) Studying of development of convulsions after influences of
strychnine.d) Ideas about Neuroses.
4
9 III quiz 3
The plan of lectures on “Pre-medical help”
N Themes Hours1 The organisation of the surgical help. Pre-medical help to
patients. Antiseptics and aseptics, types2
2 Injuries, classification. Diagnostic, first aid, principles of treatment. Bandages. Bleedings, classification. Methods of temporary control of the bleeding, burns, first id, treatment, frostbite, wounds, fractures, diagnostics, medical tires, principles of applying
2
3 Surgical infection, classification. Principles pre-medical help of 2
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the surgical infection. Furunculus, carbunulus, paraproctitis, gaseous gangrene, osteomielitis, peritonitis diagnostics pre-medical help. Terminal conditions, failing of the vital signs, resuscitation measures. Syncope, collapse. A stenocardia. A myocardium heart attack A bronchial asthma. Snake bite. Drug poisoning. The pre-medical help
The plan of lectures practical training on “Pre-medical help”
N Themes Hours
1 The organisation of the surgical help. Before and after the operational pre-medical help to patients
2
2 Antiseptics and aseptics, types 23 Injuries, classification. Diagnostic, first aid, principles of
treatment. Bandages, classification. Types of bandages2
4 Bleedings, classification, clinical presentation, diagnostics. Methods of temporary control of the bleeding. The diagnostics of the internal bleeding and calculating of the blood loss volume. Blood groups and methods of their detection. Burns. Thermal , chemical, electric and radiation burns, first id, treatment
2
5 Frostbite, stages, first aid, treatment 26 Wounds. First aid at wounds. Crush syndrome (traumatic
toxicosis), pre-medical help2
7 Fractures, classification. Signs, diagnostics, first aid at fractures. Shinas, principles of applying. Dislocations, diagnostics, treatment, first aid
2
8 Surgical infection, classification. Local and general signs, prophylaxis of the surgical infection. Principles pre-medical help of the surgical infection
2
9 Furunculus, carbunulus, paraproctitis, gaseous gangrene, osteomielitis, peritonitis classification, clinical course, diagnostics pre-medical help
2
10 Terminal conditions, failing of the vital signs, resuscitation measures. Syncope, collapse. First aid
2
11 Urgent therapeutic diseases. A sunstroke. A stenocardia. A myocardium heart attack. Acute pulmonary insufficiency. A bronchial asthma. A coma. First aid, treatment
2
12 Poisonings. Snake bite. Drug poisoning. The pre-medical help 2
Thematic plan of lectures on toxicologicalchemistry (autumn semestr)
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№ Topic hours
1. The group of poisonous substances, substances isolated with acidified water and acidified alcohol. Specificity the methods used.
2
2. The method of Kramarenko. Derivatives of barbituric acid. 23. Alkaloids, purification methods, and precipitation and colored
reactions. Methods for the quantitative definition, classification.2
Thematic plan of practical trainingon toxicological chemistry (autumn semestr)
№ Topic hours
1. Toxic substances extracted from acidified solution. Barbiturates and chemical-toxicological analysis.
4
2. Substances with acidic properties (salicylic acid and its derivatives), their chemical toxicological analysis.
4
3. Substances extracted from alkaline solution. Alkaloids. Methods of quantitative and qualitative analysis. The chemical-
toxicological analysis of derivatives of pyridine and piperidine. 4
4. The chemical-toxicological analysis of derivatives of tropane. 45. The chemical-toxicological analysis of derivatives of quinoline
and isoquinoline. 4
6. The chemical-toxicological analysis of derivatives indole. 27. The chemical-toxicological analysis of derivatives purine and
pirrolizidin.2
8. The chemical-toxicological analysis of the synthetic substances of basic character.
2
9. Poll. Repeat lessons learned. 210. The chemical-toxicological analysis of derivatives phenothiazine
(aminazine, diprazine, levomepromazine).2
11. The chemical-toxicological analysis of derivatives Benzodiazepine (chlozepid, nitrazepam, nozepam, diazepam).
2
12. Cardiac glycosides and saponins, the chemical-toxicological analysis.
2
13. Toxic substances (pesticides), extracted from biological material in organic solvents. The chemical-toxicological analysis of the pesticides containing chlorine.
2
14. Derivatives of phenol and carbamic acid. 215. Poll. The final lesson. 1
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