veterinary quarterly review extension veterinary medicine...

6
BEEF CATTLE PRACTICE Update on Diagnosis of Trichomoniasis Trichomoniasis is one of the most devastating diseases of cattle. Although it no doubt has been present in Texas beef herds for many decades, it has been diagnosed with increased fre- quency in recent years throughout the state. Steps to diagnose trichomoniasis are critical to investigation of repro- ductive problems in beef herds. e following material covers important points about current guide- lines for diagnosis of the disease. Reproductive Impact of Trichomoniasis e two most common ways Trit- richomonas foetus is introduced into Texas beef herds are by bulls or cows from a herd infected with T foetus Extension Veterinary Medicine College of Veterinary Medicine & Biomedical Sciences Volume 22, Number 4 Winter 2006-2007 Department of Large Animal Clinical Sciences, CVM, TAMU, College Station, Texas 77843 This is number eighty-seven of a continuing series of multi-species quarterly reviews and practice tips for veterinarians in Texas. Information in the Veterinary Quarterly Review is intended to be timely, concise and of practical value. Ideas and input from practicing veterinarians are encouraged. Sources of abstracts, articles or practice tips will be credited. In this issue 1. Update on Diagnosis of Trichomoniasis 2. Ethanol Boom Causing Multifaceted Paradigm Shift throughout Food Production Systems 3. Resources for Current DDGS Recommendations for Livestock and Poultry Feed 4. “A Producer’s Guide to Managing Porcine Circovirus-Associated Disease” Available 5. Nuflor® Oral 2.3% Concentrate Solution Available as Swine Drinking Water Medication 6. New Guidelines for Maximum Residue Limits (MRLs) for Pork Exported to Japan Changing How U.S. Swine Veterinarians and Producers Manage Drug Withdrawal Times 7. Placenta Submission Becoming More Important for Equine Abortion Diagnosis 8. Small Scale Composting as Practical Way To Dispose of Horse Manure 9. Sheep Management Classes Available Online 10. Marijuana Toxicosis in Dogs: 213 Cases 11. Veterinary Continuing Education Seminars 2007, Texas A&M University Educational programs of Texas Cooperative Extension are open to all people without regard to race, color, sex, disability, religion, age or national origin. The Texas A&M University System, U.S. Department of Agriculture, and the County Commissioners Court of Texas Cooperating slipping through poor fences to infect a clean neighboring herd; and by placing a newly purchased non-virgin bull that is infected with T foetus into a clean herd. Bulls that have had breeding experience must be tested for trichomoniasis prior to mixing with a clean herd! Following infection of cows with T foetus, conception occurs at a mod- erately reduced rate accompanied by embryonic deaths and abortions. e most common outcome of T foetus infections is early embryonic death, which results in repeat breeders. Traditionally, abortions due to tricho- Bruce Lawhorn Visiting Professor, Swine Practice F.C. Faries, Jr. Extension Program Leader for Veterinary Medicine Steve Wikse Associate Professor and Extension Veterinarian — Beef Cattle Veterinary Quarterly REVIEW

Upload: others

Post on 19-Jun-2020

2 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: Veterinary Quarterly REVIEW Extension Veterinary Medicine ...aevm.tamu.edu/files/2010/06/VQR_Wntr06-07.pdfthe infection by the time of pregnancy examinations. Culture of samples col-lected

BEEF CATTLE PRACTICEUpdate on Diagnosis of Trichomoniasis Trichomoniasisisoneofthemostdevastatingdiseasesofcattle.AlthoughitnodoubthasbeenpresentinTexasbeefherdsformanydecades,ithasbeendiagnosedwithincreasedfre-quencyinrecentyearsthroughoutthestate.Stepstodiagnosetrichomoniasisarecriticaltoinvestigationofrepro-ductiveproblemsinbeefherds. Thefollowingmaterialcoversimportantpointsaboutcurrentguide-linesfordiagnosisofthedisease.

Reproductive Impact of Trichomoniasis ThetwomostcommonwaysTrit-richomonas foetusisintroducedintoTexasbeefherdsarebybullsorcowsfromaherdinfectedwithT foetus

Extension Veterinary MedicineCollege of Veterinary Medicine& Biomedical Sciences

Volume 22, Number 4 Winter 2006-2007Department of Large Animal Clinical Sciences, CVM,

TAMU, College Station, Texas 77843This is number eighty-seven of a continuing series of multi-species quarterly reviews and practice tips for veterinarians in Texas. Information in the Veterinary Quarterly Review is intended to be timely, concise and of practical value. Ideas and input from practicing veterinarians are encouraged. Sources of abstracts, articles or practice tips will be credited.

In this issue 1.UpdateonDiagnosisofTrichomoniasis 2.EthanolBoomCausingMultifacetedParadigmShiftthroughoutFoodProduction Systems 3.ResourcesforCurrentDDGSRecommendationsforLivestockandPoultryFeed 4.“AProducer’sGuidetoManagingPorcineCircovirus-AssociatedDisease”Available 5.Nuflor®Oral2.3%ConcentrateSolutionAvailableasSwineDrinkingWater Medication 6.NewGuidelinesforMaximumResidueLimits(MRLs)forPorkExportedtoJapan ChangingHowU.S.SwineVeterinariansandProducersManageDrugWithdrawal Times 7.PlacentaSubmissionBecomingMoreImportantforEquineAbortionDiagnosis 8.SmallScaleCompostingasPracticalWayToDisposeofHorseManure 9.SheepManagementClassesAvailableOnline10.MarijuanaToxicosisinDogs:213Cases11.VeterinaryContinuingEducationSeminars2007,TexasA&MUniversity

Educational programs of Texas Cooperative Extension are open to all people without regard to race, color, sex, disability, religion, age or national origin.

The Texas A&M University System, U.S. Department of Agriculture, and the County Commissioners Court of Texas Cooperating

slippingthroughpoorfencestoinfectacleanneighboringherd;andbyplacinganewlypurchasednon-virginbullthatisinfectedwithT foetusintoacleanherd.Bulls that have had breeding experience must be tested for trichomoniasis prior to mixing with a clean herd!

FollowinginfectionofcowswithT foetus,conceptionoccursatamod-eratelyreducedrateaccompaniedbyembryonicdeathsandabortions.ThemostcommonoutcomeofT foetusinfectionsisearlyembryonicdeath,whichresultsinrepeatbreeders.Traditionally,abortionsduetotricho-

Bruce LawhornVisiting Professor, Swine Practice

F.C. Faries, Jr.Extension Program Leader

for Veterinary Medicine

Steve WikseAssociate Professor and Extension

Veterinarian — Beef Cattle

Veterinary Quarterly REVIEW

Page 2: Veterinary Quarterly REVIEW Extension Veterinary Medicine ...aevm.tamu.edu/files/2010/06/VQR_Wntr06-07.pdfthe infection by the time of pregnancy examinations. Culture of samples col-lected

� VeterinaryQuarterly

moniasiswerefelttooccurmainlyinearlypregnancy.Itisnowwellproventhattheycanoccurthroughoutgesta-tionrightuptothetimeofcalving.It’sanewideatoconsiderT foetusinfec-tionasanimportantpotentialcauseofmid-orlate-gestationabortions.How-ever,onestudyshowedthatathirdofT foetusabortionsoccurredinthelasttrimester. Pregnancyratesinthehigh70percentilesoccurredinrecentclinicaltrialswherereplacementheiferswerebredbyinfectedbullsandwherepreg-nancywasexaminedearly.Abortionsthenoccurredintheweeksfollowingpregnancydiagnosis.Undernaturalconditions,pregnancyratescanbedismallylow(inthe50to65percentrange)duringthefirstyearofinfectioninanaiveherd. InanoutbreakIencountered,abreedinggroupof161cowsdroppedfromapregnancyrateof92percentonefallto65percentthenextfall.(Therewere10neighborcowsinthecorralwithmyclient’scowsthatfall.)Beefherdsthathavebeeninfectedforyearsmayhavepregnancyratesinthehigh70percentilesduetodevel-opmentoftransitoryimmunityininfectedcows. Inoutbreaksoftrichomoniasis,palpationmayrevealthatthereisalowerthannormalpercentageofcowsinthelasttrimesterofpregnancyandahighernumberofcowspregnantinearliertrimesters.Thisisespeciallytrueinherdswithlongbreedingsea-sons(6to8months).Cowsbecomeinfectedinthefirstcoupleofmonthsofthebreedingseason,butclearinfec-tionin1to4monthsandbecomepregnant.Thisleadstohugeincreases(3months)incalvingintervalsandlowerweaningweights.

Diagnosis of Trichomoniasis Diagnosisoftrichomoniasisisachallengebecauseotherreproduc-tivetractinfectiousagentscanpaintsimilarclinicalpicturesinbeefherds.ReproductivelossesduetoCampylo-bacter foetus,Leptospira hardjo-bovisandbovineviraldiarrheavirusinfec-

tioncanbeindistinguishablefromthoseofT foetus.Theoccurrenceofpyometrainasmallpercentageofcasesisanimportantuniquemani-festationoftrichomoniasis.DiagnosisoftrichomoniasisisaccomplishedbyvisualizingthemotileorganismsinculturesorbyidentifyingDNAoforganismsinsamplesortissues.Diag-nosis can be made by sampling bulls, cows, fetuses or placentas. Bulls.ThetraditionalwaytodiagnoseT foetusinfectioninaherdhasbeentocultureorganismsfromsmegmacollectedfromtheprepuceofbulls.Thereareseveralwaystocollectthesmegmasample,includingpre-pucewashingsofsaline,dabbingwithcottonswabsandscrapingcombinedwithaspirationintoapipette. Thepipette,ordrymethod,ispre-ferredintheUnitedStates.Thepre-puceistrimmed,anda21-inchsterileinseminationpipetteisinsertedintothefornixoftheprepuce.Thepipetteisthenrepeatedlyscrapedbackandforthabout2or3inchesinthesamespotwithgentlepressurewhileapply-ingsuctionwitha12or20ccsyringe. Idothatabout40times,graduallytryingtodigdeeperintotheepithelialcryptsofthemucosawheretheorgan-ismsaremostabundant.Aportionofsamplescollectedthatwaywillconsistofgreymucus.Somewillhavejustenoughbloodtoturnpink.Diagnosti-ciansfeelthatsampleswithnobloodarepositivejustasmuchasthosewithalittleblood,butmanyotherpractitionersandIthinksamplesthatarealittlepinkarethebest.Itisnotgoodtocollectasamplethatlookslikepurebloodorasamplewithalotofdirt.Bloodysamplescan’tbehelpedinbullsthathaveaninflamedprepucemucosathatyieldsbloodwiththeslightestscraping. Diagnosticianshatesamplesthatcontaindirt.Dirtysamplesaredif-ficulttoavoidundermuddycondi-tions.Ihavebeenabletocollectfairlycleansamplesundermuddyconditionsbyplacingasheathedpipetteintothefornixoftheprepuce,pullingthesheathbackafewinches,

scrapingwithaspiration,thenpullingthepipettebackintothesheathandremovingitfromtheprepucecoveredbythesheath.Analternativemethodofobtainingacleansampleistowashthesheathpriortosampling.Sinceit’snaturaltoholdportionsofthepipettethatarecontaminatedwhencollectingsamples,Iliketowearafreshpairofexamglovesforeachsamplingtopre-ventcrosscontaminationofsamples ThemucuscollectedinthepipetteisthendepositedintoanIn Pouch TFpacket(BiomedDiagnostics,SanJose,California).Survivaloforgan-ismsfromcollectionattheranchtoincubationatthediagnosticlaboratoryismuchhigherinIn Pouch TFpacketsthanDiamond’smedia.BesuretheIn Pouch TFpacketexpirationdatehasnotpassed.VeterinarianswhohavebacterialincubatorscanincubateandreadtheInPouchTFpacketsintheirclinics.Theyshouldbereadevery24hoursfor5days.Organismsaremostcommonlyobserved(at40X,100X,400X)inpositivesamplesat48hoursofincubation,butcanbefoundany-timebetween24hoursand5days. Samplesgenerallyshouldbeincubatedat37C.However,somelaboratoriesfavor36C.StudieshavedemonstratedthesameisolationrateofT foetuswhensampleswereincu-batedat22Cas37C.IknowthatT foetusissensitivetoexcessiveheatbutmighthaveoverheatedsomesamplesinmyincubatorthatwasaccidentallysetat42C.Consequently,Inowsettheincubatorat36CwhenIreadmyownsamples.Organismsareeasytoseeunderagoodlightmicroscopeandlooklikelittlebumpercarsrunningaroundhittingintoeachother. TheTexasVeterinaryMedicalDiagnosticLaboratoryhasdevelopedapolymerasechainreaction(PCR)testforpositivelyidentifyingtheDNAoforganismspresentinpositivetestsofT foetus.Since1999,whenintestinaltrichomonads(Tetratrichomonasspp,Pentatrichomonas hominisandothers)wereculturedfrompreputialsmegmaoftrulyvirginbulls,ithasbecomeprudent to perform PCR tests on all

Page 3: Veterinary Quarterly REVIEW Extension Veterinary Medicine ...aevm.tamu.edu/files/2010/06/VQR_Wntr06-07.pdfthe infection by the time of pregnancy examinations. Culture of samples col-lected

VeterinaryQuarterly �

positive cultures.Itwouldbeatragicmistaketosendanexcellentbulltoslaughterbecauseofapositiveculturethatwasactuallyanonpathogenicintestinaltrichomonad.ThePCRtestismuchmoresensitivethancultureinidentifyingT foetusinsamples.Forexample,inanoutbreakoftricho-moniasiswhichIdiscoveredatapregnancyexamination,3of6culturesofsamplescollectedfromopencowswereculturepositive.Inaddition,5ofthe6sampleswerePCRpositive.(PCRdetected2morepositives).IoftenrequestbothcultureandPCRtestingofsamplesIcollectbecausethecombinationmightincreasetheoddsofdiagnosingT foetusinfectionifitispresentintheherd.PCRtestsareperformedfollowingincubationoftheIn Pouch TFfor5days. Cowsorheifers.Althoughcultureofsmegmasamplescollectedfromtheprepuceofbullsisthestandardwaytodiagnosetrichomoniasisinbeefherds,cultureofuterinedischargesfromfemalesfoundopenatpregnancydiag-nosiscanbejustaseffective.Enlargeduterinehornswiththickenedwallscanbedetectedinsomeoftheopencowsatpalpation.Examinationoftheante-riorvaginaofthesecowsviaavaginalspeculumoftenrevealsagreytoyel-lowpurulentdischarge.Adisposablemarevaginalspeculumworkswell.It’seasytocollectasampleofexudatetoculturebysweepingthefornixofthevaginawithaglovedhand.Itcanalsobedonebyaspirationofexudateintoaninseminationpipetteinsertedtothefornixofthevagina.Thesameproce-durecanbeusedtoobtainasampleofexudatefromtheoccasionalcowthatdevelopspyometra. It’simportanttocollectsamplesfromatleast6opencowsbecausetheimmunesystemofsomecowsthatwereinfectedwithT foetusearlyinthebreedingseasonwillhaveclearedtheinfectionbythetimeofpregnancyexaminations.Cultureofsamplescol-lectedfromcowsatpregnancyexami-nationinherdswithimpairedfertility

offersaquickwaytodetermineiftrichomoniasisistheculprit. Fetuses.Diagnosisoftrichomonia-siscanbemadebyexaminingabortedfetusesbycultureoftheorganismsfromabomasalfluid.Itcanalsobedonebyvisualizationoftheorganismsintheplacentaorfetaltissues.ThereareconsistentpatternsoflesionsintheplacentaandfetusofabortionscausedbyT foetus.Inoverhalfthecases,bronchopneumoniawithorgan-ismsinairwaysisclearlydiscernableinstandardhematoxylinandeosin(HE)-stainedsections.Organismssometimescanbeseenbypathologistsinsectionsoftheeosophagus,aboma-sumandintestine.Theycanalsobeseenintheplacentaifitisnotseverelyautolyzed.

Bottomline TrichomoniasisisacommoncauseofseverereproductivelossesinTexasbeefcow/calfoperations.Severalotherinfectiousagentscancausereproductiveproblemssimilartothoseseeninoutbreaksoftrichomo-niasis.However,pyometraisauniquemanifestationofT foetusinfection.Lowerpregnancyratesanddelayedpregnanciesthatresultinlowerwean-ingweightsmaketrichomoniasisoneofthemosteconomicallydevastatingdiseasesofbeefcattleherds. Newdiagnosticaids,suchastheIn Pouch TFpacketandthePCRtest,havemadeeffortstodiagnosetricho-moniasismoresuccessful.Diagnosescanbemadefromsamplescollectedfrombulls,cowsorheifersandfromabortedfetusesortheirplacentas.Attemptstodiagnosetrichomoniasismustbeacriticalpartofallinvestiga-tionsofimpairedfertilityinTexasbeefherds. Remembertheoldsaying,“Ifyoudon’tlookforit,youwon’tfindit!”FromStevenE.Wikse,DVM,DACVP,AssociateProfessorandExtensionBeefCattleVeterinarian,FoodAnimalSection,DepartmentofLargeAnimalClinicalSciences,CollegeofVeterinaryMedicineandBiomedicalSciencesandTexasCooperativeExtension,TheTexasA&MUniversitySystem,CollegeStation,Texas77843-4475.

FOOD ANIMAL PRACTICEEthanol Boom Causing Multifaceted Paradigm Shift throughout Food Production Systems ArecentIowaStateUniversityCen-terforAgricultureandRuralDevelop-ment(CARD)paperprovidesvariouspreliminaryscenariosaboutthelong-termimpactofcorn-basedethanolonthegrain,oilseedandlivestocksectorsofU.S.agriculture. Theexecutivesummaryofthepaperstates:“Estimatesofthelong-runpotentialforethanolproductioncanbemadebycalculatingthecornpriceatwhichtheincentivetoexpandethanolproductiondisappears.UndercurrentU.S.ethanoltaxpolicy,ifthepricesofcrudeoil,naturalgas,anddrieddistillersgrainswithsolubles(DDGS)stayatcurrentlevels,thenthebreak-evencornpriceis$4.05perbushel.Amulti-commodity,multi-countrysystemofintegratedcommoditymodelsisusedtoestimatetheimpactsifweevergetto$4.05perbushelcorn.Atthisprice,corn-basedethanolproductionwouldreach31.5billiongallonsperyear,orabout20percentoftheprojectedU.S.fuelconsumptionin2015.Supportingthislevelofproductionwouldrequire95.6millionacresofcorntobeplanted.Totalcornproductionwouldbeapproximately15.6billionbushelsofcorn,comparedto11.0billionbushelstoday.Mostoftheadditionalcornacrescomefromreducedsoybeanacreage.Wheatmarketswouldadjusttofulfillincreaseddemandforwheat.U.S.cornexportsandproductionofporkandpoultrywouldallbereducedinresponsetohighercornpricesandincreasedutilizationofcornbyetha-nolplants.Theseresultsshouldnotbeviewedasapredictionofwhatwilleventuallymaterialize.Rather,theyindicatealogicalendpointtothecur-rentincentivestoinvestincorn-basedethanolplants.”

Page 4: Veterinary Quarterly REVIEW Extension Veterinary Medicine ...aevm.tamu.edu/files/2010/06/VQR_Wntr06-07.pdfthe infection by the time of pregnancy examinations. Culture of samples col-lected

� VeterinaryQuarterly

Thepaperfocusesonthewinnersandlosersbyconcluding,“Muchofthedebatesurroundingthecurrentincentivestotheethanolsectorsug-geststhattheseincentivesaredriveninlargepartbyadesiretoreduceU.S.dependenceonimportedoil.Bystimulatingtheproductionofethanoltoasmuchas20percentoftotalfueluse,theseincentivestructuresappeartobewellontheirwaytomeetingthisgoal.” Otherbeneficiariesincludelandowners,whowillbenefitfromadramaticincreaseincornpricesandassociatedincreasesinlandrents.U.S.cropgrowerswillbenefituntilthehigherprofitsarecapturedbyhigherlandvaluesandlandrents.DairyandbeefproducerswhoarenearethanolplantswillbenefitfromhavingaccesstoDDGS.Ownersofethanolplantswillbenefituntilcornpricesrisetoeliminatethecurrentarbitrageinethanolproduction. Specializedporkandpoultryproducerswhodonotownsharesinethanolplantswillloseashighercornprices(andeventuallyreducedinternationalcompetitiveness)causeproductionlevelstodecline.Thetransitiontotheselowerproductionlevelswillbepainfulformostoftheseproducers.Ethanolconstructionandtheflowofprofitsfromethanolfacili-tieswillstimulateruraleconomies.However,therewillbelesslivestockinthesesameareaswhichwilleventuallyworktooffsetthisadvantage. Astandardargumentininterna-tionaltradeisthat,whilemosttradearrangementshavewinnersandlosers,thesuccessfulagreementsaresobeneficialtothewinnersthattheycreateenoughsurplustohelpthelosersadjustandadapt.Aninterest-ingpolicyquestionthatweareintheprocessofaddressingiswhetherthelonglistofpositivesassociatedwiththeexpansionofcorn-ethanolproduc-tionissufficienttooffsettheshorterlistofnegatives.Thediscussionsfromtheentirepapercanbeaccessedathttp://www.card.iastate.edu/publica-tions/DBS/PDFFiles/06bp49.pdf .

AdaptedfromAmaniElobeid,SimiaTokgoz,DermotJ.Hayes,BruceA.BabcockandChadHart,CARDBriefingPaper06-BP49,“TheLong-RunImpactofCorn-BasedEthanolontheGrain,Oilseed,andLivestockSectors:APreliminaryAssessment,”November2006,CenterforAgricultureandRuralDevelopment,IowaStateUniversity,Ames,Iowa,50011-1070,www.card.iastste.edu.Forinformationaboutthispaper,contactBruceBabcockat578HeadyHall,IowaStateUniversity,Ames,Iowa50011-1070;(phone)515/294-6785;(fax)515/294-6336;or(email)[email protected].

Resources for Current DDGS Recommendations for Livestock and Poultry FeedTheUniversityofMinnesotaoffersanexcellentresourceonthemostcurrentinformationonuseofdistillersdriedgrainandsolubles(DDGS)indairy,beef,swineandpoultryrations.Youcanfinditatwww.ddgs.umn.edu/.AnotherexcellentresourcebytheNationalCornGrowersAssociation(NCGA)isa16-pagepamphletthatoutlinesthebasicDDGSfeedingrec-ommendationsforbeefanddairycat-tle,swine,sheepandpoultry.ItbreaksdownthemaximumdietaryinclusionlevelsforrationsandexplainshowbesttoutilizeDDGS.Contactinfor-mationforquestionsisalsoincluded.YoucanorderthispamphletfromMelGibsonat636/733-9004.Itisacon-densedversionoftheOctober2005NCGA’s“DistillersGrainFeedingRecommendations,”whichisavailablefromNCGAatwww.ncga.com.FromPork Magazine,November2006,pp.8and10.

SWINE PRACTICE“A Producer’s Guide to Managing Porcine Circovirus-Associated Disease” AvailableTheAmericanAssociationofSwineVeterinariansandtheNationalPorkBoardhaveteameduptocreateanexcellentinformationsource,“AProducer’sGuidetoManagingCirco-virus-AssociatedDisease.”Itprovidesguidelinesforswineproducerswhoaredealingwithporcinecircovirus-

associateddisease(PCVAD).ItsvarioustopicsincludediseasesignsofPCVAD,importanceofaveterinary-assisteddiagnosisandmeasureshelp-fultominimizetheeffectofPCVADineachstageofproduction.This18-page,colorguidecanbeviewedathttp://www.aasv.org/aasv/documents/PCVADBrochure.pdf.Printcopiesarefreeforproducersandindustryedu-catorsfromThePorkStoreatwww.porkstore.pork.org.ClickonResourcesandthenSwineHealth.FromtheAmericanAssociationofSwineVeterinarians,9021stAvenue,Perry,Iowa,50220-1703;(phone)515/465-1703;(fax)515/465-3832;(email)[email protected];(website)www.aasv.org.AlsofromtheNationalPorkBoard,1776Northwest114Street,DesMoines,Iowa50325;(phone)515/223-2600;(fax)515/223-2646;(email)[email protected];(website)www.pork.org.

Nuflor® Oral 2.3% Concentrate Solution Available as Swine Drinking Water Medication FlorfenicolSolution(Nuflor®Oral2.3%ConcentrateSolution)wasapprovedinJuly2006asdrinkingwatermedicationforswinetotreatswinerespiratorydiseaseassociatedwithActinobacillus pleuropneumoni-ae,Pasteurella multocida,Salmonella choleraesuisand Strep suisType2infections. TherecommendeddosageofNuflor®Oral2.3%ConcentrateSolu-tionis10mg/kgperday.Thisresultsfromproducingastocksolutionthatwillmedicate128gallonswitheachgalloncontaining400mgflorfenicol(100ppm).Itisonlyavailableas2.2litersina1-gallonplasticbottle.Eachbottlemedicates128gallonsofdrink-ingwater.Themedicatedwatershouldbethepigs’onlysourceofdrinkingwaterforfiveconsecutivedays.Thepreslaughterwithdrawalperiodis16days.FromSchering-PloughAnimalHealthCorporation,556MorrisAvenueBldgS4,Summit,NewJersey07901.QuestionsshouldbeaddressedtoSchering-Ploughtechnicalserviceveterinarianat877/633-3953oratwww.spah.com/usa/swine.

Page 5: Veterinary Quarterly REVIEW Extension Veterinary Medicine ...aevm.tamu.edu/files/2010/06/VQR_Wntr06-07.pdfthe infection by the time of pregnancy examinations. Culture of samples col-lected

VeterinaryQuarterly �

New Guidelines for Maximum Residue Limits (MRLs) for Pork Exported to Japan Changing How U.S. Swine Veterinarians and Producers Manage Drug Withdrawal Times

Maximum Residue Limits for Pork Exported to Japan – the Facts RecentlytheJapanesehaveadoptednewfoodsafetystandardsandresiduestandardsthatwillapplytoallfoodproductsincludingpork,freshandfrozen,offalandprocessedmeats.ThesenewstandardsarebasedontheCodexAlimentarius,aseriesofinter-nationalstandardsestablishedbytheFoodandAgriculturalOrganizationoftheUnitedNationsandtheWorldHealthOrganizationtoensurefoodsafety.U.S.standardsweredevelopedbytheFoodandDrugAdministra-tiontoensurefoodsafety.CodexandU.S.residuestandardsmaydifferforcertainproductsandresiduetesting.CompliancewithU.S.productwith-drawalswillsatisfymost,butnotall,ofthenewmaximumresiduelevels(MRLs)setbyJapan. Japanrepresentsamarketforover$1billionofU.S.porkor45percentofthevalueofU.S.exports.Infact,itisthelargestmarketforU.S.porkinvolumeandvalue.Japanpurchasesapproximately753millionpoundsofU.S.porkmuscle.Oneanimalinviola-tionofJapaneseproductspecificationscanseverthismarketforU.S.pork.

Testing Protocols for Pork Products Exported to Japan Specifictestingprotocolsforveterinarydrugsinporkandporkproductswillbeclarifiedasinforma-tionbecomesavailable.Japanesetest-ingprotocolsforporkmusclerequiretestingbedoneatornearidentifiableinjectionsites.Therefore,theuseofinjectableproductsrepresentsmoreofariskthantheuseofotheranimalhealthproductsusedinthefinishingstage.Producersareencouragedto

evaluatetheuseofanimalhealthprod-ucts,includinginjectables,intheirfin-ishersandreviewinjectiontechniques.

What the Pork Checkoff Is Doing ThePorkCheckoffhasbeenwork-ingwithpharmaceuticalcompaniestodeterminewhatanimalhealthprod-uctsmayrequirechangesintheirwith-drawalperiodstomeetJapanMRLs.ThePorkCheckoffwillcontinuetoupdateitssiteathttp://www.pork.org/Producers/JapanMRL.aspxwiththelatestinformationfrompharmaceuti-calcompanies.(Informationfromtheindividualpharmaceuticalcompaniescanbefoundthroughthe“MoreInfo”linkatthebottomofthewebsitepage.)

What This Means to the Swine Producer CertainveterinaryproductswillrequirelongerwithdrawalperiodsifswinearebeingsenttoapackingplantthatchannelsporkintoaJapaneseexportmarket.Followingveterinarydrugmanufacturers’directionsforcorrectuseofanimalhealthproductsisessential.

What Producers Need To DoSwineproducersareadvisedtotakethefollowingstepstofindoutiftheyareaffectedbythesenewregulations:

•ContactyourpackerandfindoutifyourproductisbeingchanneledintotheJapaneseexportmarketandisaffectedbynewMRLs.

•Searchthelistofanimalhealthproductsinthedatabaseofthewebsitehttp://www.pork.org/Producers/JapanMRL.aspx.Viewthosethatarecurrentlyusedinthefinisherphaseofyouropera-tiontoseeiftheirwithdrawalperiodsareneededifyouareintheJapaneseexportmarket.

•Contactyourherdveterinarianifyouhavequestionsaboutwhethertheanimalhealthproductslistedinthiswebsiteareusedinyouroperationandareaffectedandrequireachangeinusage.

•Withthehelpofyourherdveteri-narian,developprotocolsfortheuseofanimalhealthproducts.

Theseprotocolsshouldinclude(1)aproceduretodetermineifanimaltreatmentisnecessaryandwhenisthemosteffectivetimetotreatananimal,and(2)atooltodeterminethemostappropriateproductstouseandthecorrecttechniquefortreatmentofpigsinthefinisherstageofproduction.

Japan MRLs Position Statement Adopted by the American Association of Swine Veterinarians (AASV)Gotohttp://aasv.securesites.net/aasv/ position-japanMRL.htmlfortheAASVpositionstatementonJapaneseMRLs.AdaptedfromMaximumResidueLimits(MRLs)forPorkExportedtoJapan,http://www.pork.org/ Producers/JapanMRL.aspx;andfrom“AASVRecommendationstoMeetJapaneseMRLRequirementsofU.S,”AmericanAssociationofSwineVeterinarians,9021stAvenue,Perry,Iowa50200,http://aasv.securesites.net/aasv/position-japanMRL.html

EQUINE PRACTICEPlacenta Submission Becoming More Important for Equine Abortion Diagnosis Duetocontinuingprogressintheknowledgeandidentificationofequineplacentalabnormalities,asmanyas80percentofequineabortioncasesmaybeassociatedwithplacentalchanges.Theplacenta,amnionandumbilicus(fetalmembranes)arecriti-calspecimensforsubmissioninallequineabortioncases.Also,thefetus,dam’sseraandserafrom10percentofnormalpregnantmaresatthesamelocationshouldstillbesentifpossible.FromtheOklahomaStateUniversity(OSU)Animal Health Update,thenewsletteroftheOSUCenterforVeterinaryHealthServices,Winter2006.

Small Scale Composting as Practical Way To Dispose of Horse Manure TheTexasCooperativeExtension(TCE)publication,“CompostingHorseManure”(B-6084),isacompleteguideforsmallscalecompostingof

Page 6: Veterinary Quarterly REVIEW Extension Veterinary Medicine ...aevm.tamu.edu/files/2010/06/VQR_Wntr06-07.pdfthe infection by the time of pregnancy examinations. Culture of samples col-lected

� VeterinaryQuarterly

Veterinary Continuing Education Seminars 2007 College of Veterinary Medicine and Biomedical Sciences

Texas A&M University*April27-29...................................................................................................AnnualFelineSymposium (Dr.JohnAugust)*June1-3............................................................................................ AnnualFoodAnimalConference (Dr.StevenWikse)*July21-22.......................................................................................................... SmallAnimalDentistry (Dr.Jonathan“Bert”Dodd)*August4-5......................................................................................................DermatologyConference (Dr.ChristineRees)*September22-23................................................................................AnnualExoticPetsConference (Dr.SharmanHoppes)*October12-14....................................................................................ClinicalNeurologyConference (Dr.JonathanLevine)*November2-4........................................................................................... AnnualEquineConference (Dr.JeffreyWatkins)*November17-18........................................SmallAnimalEmergencyMedicineandCriticalCare (Dr.MaureenMcMichaels)*November30-December2.......................................... AnnualEquineReproductionSymposium (Dr.DicksonVarner)*ConfirmedCalendarissubjecttorevision.Formoreinformationontheseprogramsofself-studyandpersonalizedcontinuingeducation,pleasecall(979)845-9102,fax(979)862-2832,[email protected]://www.cvm.tamu.edu/vtce.

FromtheOfficeofVeterinaryContinuingEducation,TexasVeterinaryMedicalCenter,CollegeStation,Texas.

horsemanuregeneratedatveterinaryclinicsandstables.Itbrieflydescribescomposting,compostmaturity,optimalconditionsforcomposting,makingcompostfromhorsemanure,measuringcomposttemperatures,monitoringcompostmaturity,labora-toryanalysisofcompost,tipsforthesmallscalecomposterandacompost-ingdemonstrationcarriedoutonaveterinarylargeanimalhospital.Italsoaddressesmodestincomegenerationfromfinishedcompost. ThisandotherTCEpublicationsmaybedownloadedorcanbepur-chasedfromtheTCEBookstoreathttp://tcebookstore.org.FromTexasCooperativeExtension’sB-6084,“CompostingHorseManure”(6-99),BertW.Averman,AssociateProfessorandExtensionAgriculturalEngineer;LarryMcDonald,ExtensionAssociate/WaterQuality;RobertDevin,RandallCountyExtensionAgent-Agriculture;andJohnSweeten,ProfessorandDirector,TexasAgricultureExperimentStation,Amarillo,TheTexasA&MUniversitySystem.

SHEEP AND GOAT PRACTICESheep Management Classes Available Online IntroductiontoSheepManage-ment,IntroductiontoSheepHealthandEweRationFormulationareonlinecoursesofferedtosheepenthusiasts(adultandyouth)bythePipestoneLambandWoolProgram.Thisisasheepmanagementeduca-tion/consultingprogramofferedbyMinnesotaWestCommunityCollegeinPipestone,Minnesota.

•IntroductiontoSheepManage-mentisa14-lesson,self-pacedcoursewithcontinuousenroll-mentandprovidesanoverviewofyear-longsheepmanagement.

•IntroductiontoSheepHealthismorestructured,isdesignedformoreinteractionandrequiresthetext,Gate’s Practical Guide to Sheep Disease Management (3rdedition).

•EweRationFormulationisstruc-tured,isdesignedforinteraction

liketheSheepHealthcourseandrequiresthetext,The Sheep Production Handbook(2002edition).

Toregisterforoneoftheonlinecourses,[email protected]/847-7929.Youcanalsoregisteratwww.mnwest.edu/formmail/formdl.htm.Formoreinformation,visitPipe-stoneWoolandLambatwww.pipe-stonesheep.comorcontactPhilipBerg.HeisatPhilip.berg@mnwest.eduandat507/825-6799.FromSheepIndustryNews,November2006,p6.

CANINE PRACTICEMarijuana Toxicosis in Dogs: 213 Cases Marijuana(Cannabis sativa)iscommonlyusedasarecreationaldrugamonghumans.Animalsmay

beexposedfollowingingestionoraccidentalinhalationofsmoke.FromJanuary1998toJanuary2002,213incidenceswererecordedofdogsthatdevelopedclinicalsignsfollowingoralexposuretomarijuana.Amongthem,99percenthadneurologicalsignsand30percentexhibitedgastrointestinalsigns.Themarijuanaingestedrangedfrom0.5to90grams.Thelowestdoseatwhichsignsoccurredwas84.7mg/kg,andthehighestdosewas26.8g/kg.Timeforonsetofsignsrangedfrom5minutesto96hours.Manage-mentconsistedofdecontamination,sedation(withdiazepamasthedrugofchoice),fluidtherapy,thermoregula-tionandgeneralsupportivecare.Allaffectedanimalswithfollow-upinfor-mationmadefullrecoveries.AdaptedfromJancyzkP,DonaldsonCWandGwaltneyS,“TwoHundredandThirteenCasesofMarijuanaToxicosisinDogs,”Veterinary and Human Toxicology,46:1,pp.19-21,2004asreportedinAnimal Health Spectrum,MississippiStateUniversityExtensionService,Volume15,Number3,Fall2004,p.4.