vaccine business - a global vision

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    A Strategic Global Vision

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    Clin Infect Diseases 2007;44:1529-31

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    How heavy is the burden of vaccine preventable diseases?

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    The Burden of Vaccine Preventable Diseases

    1. http://www.hepb.org/hepb/statistics.htm. Accessed June 21, 20112. WHO, Hepatitis A vaccine, 2003

    3. WHO, Hepatitis A, WHO/CDS/CSR/EDC/2000.74. WHO Wkly Epidemiol Rec 2000; 75:257-64

    2 billion people have been infected 450 million people are chronic carriers 1 million people die each year from hepatitis B and

    its complications

    Hepatitis B 1

    1.5 million cases worldwide per year Estimated cost 1.5 to 3 billion 30 days of work lost per patient

    Hepatitis A 2,3

    16 million cases per year 600,000 deaths each year 4 percent mortality rate

    Typhoid 4

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    The Burden of Vaccine Preventable Diseases

    1. http://www.vaccineinformation.org/pneumchild/qandadis.asp. Accessed on July 6, 20112. Ferlay J, et al. GLOBOCAN 2002 Cancer Incidence, Mortality and Prevalence Worldwide . Lyon: IARC CancerBase, 20043. Gershon A, Takakashi M, Seward J. Varicella vaccine. In: Plotkin SA, Orenstein WA, Oxfitt PA, eds. Vaccines. Pennsylvania: WB Saunders, 2004: 784 823.

    > 40,000 cases and > 4,400 deaths per year in the US alone Case-fatality rate among adults - 20% Case fatality among elderly patients - 60%

    Pneumococcaldisease 1

    HPV 2 Worldwide, every 2 minutes a woman dies of cervical cancer Every year in Asia, 266000 women are diagnosed with cervical

    cancer and 143000 will die from the disease

    Varicella 3 Rate of complications is highest in those aged >15 yrs Mortality rate in adults ia 25.2/100,000 cases compared

    with only 1/100,000 cases in children

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    The Burden of Influenza

    1. WHO 2003; A56/23 2. Rose GW . Expert Opin. Biol. Ther. 2006; 6(3): 301-10 3. W HO. Weekly Epidemiol Rec 2005, 80(33): 277 88 4. Thompson WW, et al. JAMA 2004; 292(11): 1333-1340 Thompson WW, et al. 5. JAMA 2003; 289 (2): 179-186.

    3 - 5 million cases of severe illness per year 1,2,3

    250,000 - 500,000deaths/yr 1,2,3

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    * Our MISSION issimple:

    ERADICATE vaccinepreventable

    diseases!

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    Why are adult vaccination rates so low?What can we do about it?

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    Shot doesnt work

    Shot causes side effects

    Shot causes disease

    Didnt think of it

    Physician did not recommend

    Did not know it was needed

    Patients Reasons for Not Getting Vaccinated

    Medicare Benificiary Survey

    CDC. MMWR Morb Mortal Wkly Rep. 1999;48:886-890

    Influenza Vaccine

    Pneumococcal Vaccine

    Percent

    0 10 20 40 50 6030

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    Provider Related Barriers

    Not prevention oriented /Competing Demands

    Urgent concerns dominate visits

    Focus on acute and chronic problems

    Difficulty identifying eligible patients

    Not knowing patient immunization history

    Many Prevention Recommendations

    Adult Immunization is not a significant part of training or culture

    Ignorance and apathy about vaccine preventable disease

    Clinician is not immunized himself Clinician questions about vaccine efficacy and safety

    Nichol KL, Zimmerman RK. Arch Intern Med. 2001Silverman , et al. J cross Cult Gerontology. 2004;19:47-76

    Nowalk MP et al. J Natl Med Assoc.Kimura AC., et al. Am J Public Health. 2007; 97:684-690Prev. Med. 2005 ; 40 : 152-61

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    What can we do about to improveadult vaccination rates?

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    Strategies to Increase Adult Immunization

    1. Patient Barriers

    Increase Awareness and break down misconceptions

    Education programs

    Patient information materials

    Enhance Access

    Reduce costs

    Bring the vaccines where the patients are

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    Strategies to Increase Adult Immunization

    2. Provider Barriers

    Set an example get vaccinated

    Physician educational materials

    Training for physicians, nurses and office staff

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    Be the Change Vaccinate yourself

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    Educating Doctors

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    Strategies to Increase Adult Immunization

    3. Organization or System Barriers

    Establish a culture of immunization in your clinics

    Standing orders

    Improved tracking system/Routine Screening of vaccination

    Immunization registries

    Reminders to eligible patients

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    Changes in the System

    Shared roles between nurse and physician

    Standing orders

    written order stipulating that all persons meeting certain

    criteria (i.e., age or underlying medical condition) shouldbe vaccinated, thus eliminating the need for individualphysicians orders for each patient.

    Routine screening of vaccination status by nurses

    (part of getting vital signs)

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    Whats there outside?

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    Vaccine to fight INFECTIOUS DISEASES

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    Vaccine to fight DEGENERATIVE DISEASES

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    Medical Alternative PreventiveCLINIC

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    January 2011: 1st clinicopened Medical Alternative clinic

    July 2011: 2nd clinicopened, VACCINE businessintroduced

    Aug 2011: In HarmonyCharity Program

    Sept 2011: Soft Opening &Incorporated In HarmonyBaby & Kiddy

    Feb 2012: Website pre-launch

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    The Grow of a New Business!

    *

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    Oct 2011 Penyuntikan

    264karyawan PTBayer

    Nov 2011 Penyuntikan 26

    karyawan PTMenjangan Sakti

    Trial InternetMarketing

    Des 2011 Seminar Vaksin Flu

    & Hepatitis &penyuntikan 70Pegawai KejaksaanTinggi

    Feb 2012 Penyuntikan 80

    karyawanSoewarna Biz Park CKG Golf Club

    Launching programIHIC EXPAND

    Penandatanganankerjasama dg 3rekanan baru: CKG SMG NTT

    April 2012 Penandatanganan

    kerjasama dgKlinik Nurdin

    Rencanapenandatanganandg rekan diBandung & KF

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    IN HARMONY IMMUNITY CLINIC

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    * Klinik vaksinasi dan imunisasi utama diIndonesia

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    Partner dari berbagai institusi dan korporasiterkemuka dalam penyediaan layanan vaksinasidan imunisasi

    * Menjadi pusat pengembangan dan penelitian

    vaksinasi dan imunisasi di Indonesia

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    Jakarta Pusat

    Jakarta

    Barat

    Bogor

    Bandung

    SemarangNTT

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    * Adult Immunizations:

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