Use of Smart Dust in Blood Unit Temperature Monitoring

Group 25

James Lin BME

Adam Lowisz CompE

Advisor Dr. Dan France

Advisor Dr. Paul King

BackgroundBackground Every year Vanderbilt University Medical Center loses $600k+ Blood units need to be stored below 10 degree C; if it goes above that temperature, it is discarded Many cases of wasted blood units are unreported. Dr.

France & Dr. St. Jacques Improper handling causes blood to be wasted; many “blood

units are returned without any used, and many are never even picked up.” Dr. Anne Neff

1691 unit of blood products are lost at Vanderbilt Medical Center over a 7 month period.

Blood stored at room temperature in plastic bags make it susceptible to development of bacteria (sepsis), which may lead to mortality.

Significant cost associated with collecting, testing, preparing components, labeling, storing and shipping

Significant cost associated with collecting, testing, preparing components, labeling, storing and shipping

Significant cost associated with collection Collecting Testing Preparing components Labeling Storing and shipping blood Recruiting and educating

donors Quality assurance

Hepatitis B surface antigen (HBsAg) Hepatitis B core antibody (anti-HBc) Hepatitis C virus antibody (anti-HCV) HIV-1 and HIV-2 antibody (anti-HIV-1 and anti-HIV-2) HTLV-I and HTLV-II antibody (anti-HTLV-I and anti-HTLV-II) Serologic test for syphilis Nucleic acid amplification testing (NAT) for HIV-1 and HCV NAT for WNV

Problem DescriptionProblem Description

What can we do to preserve the blood units and prevent blood units from being used incorrectly? Smart Dust from Crossbow

Technology to monitor the blood units!

Project SolutionProject Solution

Motivation: The project was motivated by the Crossbow Smart Dust Challenge to use smart dust and wireless technology to positively impact society.

Idea for monitoring blood bags to prevent wasting units of blood came from Dr. Dan France, our advisor, a Research Assistant Professor of Anesthesiology and of Medicine.

Project DefinitionProject Definition

Objectives: To design a system that monitors the temperature of blood in bags and wirelessly transmits this information through a mesh network to a central server from which a staff member can be alerted if there are any complications with the bags.

Proposed ImplementationProposed Implementation

Advantages Ready to use Attached to bag

implies less error Disadvantage

Need a specific manufacturer for electronics sleeve

Can cost more in long term

Proposed ImplementationProposed Implementation

Advantage Modularity in Design One time cost No need for specific

bag manufacturer

Disadvantages Human error Cooling interference

Proposed System InterfaceProposed System Interface

Blood bag

Smart Dust

Blood bag

Smart Dust

Mote

Gateway

OR or ER

PC

PC: -database -Mote-VIEW

Blood Bank

Market PotentialsMarket Potentials

Clients: hospitals and blood banks Competitor: currently there are no

competitors with similar project objectives

Social ImpactSocial Impact

Less blood collection will be required from the blood banks

Preservation of life through better use of blood units

Work CompletedWork Completed

The devices have been ordered Mote (radio/processor module) MICA2DOT….$115.00

3rd Generation, Quarter-sized (25mm), Wireless Smart Sensors TinyOS - for communications and processing Battery Powered - Low Mass Wireless Communications with Every Node as a Router Capability

868/916 Multi-Channel Radio Transceiver (compatible with MICA2/MPR4xx Series) Prototype Sensor board Module MDA500……$30

Available to attach external analog input sensors

Serial Gateway………….……………………..$95.00

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QuickTime™ and aTIFF (LZW) decompressor

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QuickTime™ and aTIFF (Uncompressed) decompressor

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Work Completed (continued)Work Completed (continued)

Research completed VUMC loses $600k+ a year on blood wastage Blood cannot go above 10ºC Data acquisition module operates at 0V to 3V Formula for calculating

temperature using

MICA2DOT’s thermistor

Work Completed (continued)Work Completed (continued)

Research completed MICA2DOT

Interface

Current WorkCurrent Work

Research into software Mote-View Tiny OS nesC

Reviewing operating

manual for motes

Future WorkFuture Work

Building and refining a prototype Create server layer with

a database logger Alert method

ReferencesReferences

Dr. Paul St. Jacques Dr. Anne Neff Dr. Dan France Dr. Jim Hutchinson Mr. Efosa Ojomo

Questions?Questions?