uropathology 1 kidney
TRANSCRIPT
• Bilateral nephrectomy specimens.
• The external surface of both kidneys have a
bosselated appearance which is produced by
numerous cysts of varying sizes and
replacing the entire renal parenchyma.
• Cysts are thin walled and translucent and
filled with clear fluid.
• Adult (autosomal dominant) polycystic
kidney disease
• Cut open specimen of kidney. • The kidney is enlarged and replaced by numerous cysts
of varying sizes arising at all levels in the cortex and medulla.
• The cysts are unilocular and are filled with clear serous to hemorrhagic fluid.
• They range from a few millimeters to several centimeters.
• Normal renal parenchyma is not identified. • No mass or papillary lesions seen. • ADPKD
• A solitary poorly circumscribed solid grey white tumour is seen involving the upper calyceal system and infiltrating into the renal parenchyma.
• Foci of haemorrhage are identified in the pelvic mucosa.
• The rest of the renal parenchyma appears unremarkable.
• Urothelial carcinoma
• Nephroureterectomy specimen
• Small sized kidney
• Grossly dilated and tortuous ureter
• s/o reflux nephropathy
• Solitary well circumscribed exophytic tumour arising from the mid pole of kidney.
• Tumour is tan in colour, homogenous with a central scar.
• Rest of the renal parenchyma shows no significant pathology
• Solitary well circumscribed tumour in the upper pole of kidney.
• Tumour is mahogany brown and homogenous.
• No cystic, necrotic or haemorrhagic areas seen.
• Rest of the renal parenchyma shows no significant pathology
• HPE was Chromophobe RCC (not to be commented in exam – JUST say RCC)
• Cut open specimen of kidney with dilated pelvicalyceal system.
• The calyceal mucosa has plaques of golden yellow tissue which focally invades the renal parenchyma and extends into the perirenal fat.
• Xanthogranulomatous pyelonephritis
• Specimen of kidney.
• There is a solid white tumour involving the upper pole of the kidney.
• The tumour extends beyond the renal capsule into the perirenal fat.
• Calculi are embedded within the tumour.
• Squamous cell carcinoma with nephrolithiasis, kidney
• Renal tumour arising from the lower pole of the kidney. • Tumour is well circumscribed, solid with areas of necrosis. • The ipsilateral adrenal gland shows a tumour with the
same gross appearance as the renal tumour.• The renal parenchyma between the renal tumour and the
adrenal tumour is unremarkable.• The makes the adrenal mass a metastatic lesion and not an
extension from the primary tumour.• Also included in this image is the contra lateral adrenal
gland which appears grossly enlarged, suggesting metastatic involvement.
• (Clear cell RCC with bilateral adrenal metastasis)