university of guanajuato campus celaya salvatierra division of health sciences and engineering...
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University of Guanajuato
Campus Celaya Salvatierra
Division of Health Sciences and Engineering
Department of Nursing and Obstetrics
Dr. Nicolas Padilla Raygoza
Medical Doctor, University Autonomous of Guadalajara and University National Autonomous of Mexico, 1984
Pediatrician, Mexican Council of Certification of Pediatrics, N° 2870, 1986
Postgrade in Epidemiology. University of London, 2002
Master and Doctorate in Sciences in focus in Epidemiology, Atlantic International University, 2006
Professor Associate C and Coordinator of Support to Research and Postgraduate Studies, Department of Nursing and Obstetrics, Division of Health Sciences and Engineering, Campus Celaya Salvatierra University of Guanajuato
To describe main characteristics of rotavirusTo identify susceptible people to rotavirusTo identify the symptoms and signs from
rotavirus infectionTo describe laboratory studies to diagnosis of
rotavirus infectionTo identify and describe the treatment
Rota= wheelFamily ReoviridaeDiscovery in 1973 by Dra. Ruth BishopIt appear as a bicycle wheelSeven groups: A, B, C, D, E, F, G.Only A, B. C cause enteritis.Resistant
They will survive in the environment
UnwrappedDouble capsuleMeasure 70 nmGenome
11 RNA segmentsEncode six structural proteins and five non-
structural.Group A
14 serotypes accord to VP7 protein (G)20 serotypes accord protein VP4 (P)G and P have multiple combinations
Cause more severe and acute diarrhea in children:111 millions of cases require ambulatory care25 millions of medical consultations2 millions of hospitalized patientsFrom 352,000 to 592,000 deaths of children.
Children from 6 months to 2 yearsPre term newbornsElderlyImmunocompromisedTraveler diarrhea or sub clinic disease in
adults
World wide distribution
Peaks in winter and summerNovember - DecemberApril-May
Fecal oralPerson to person,Foods,Food handlers,Fomites
Airway
Infectiousness period 1 – 3 díasContagiousness
8 days>30 days in immunocompromised
Sudden onset with (6 days):Vomit, disappear in 24-48 hoursFever, disappear suddenlyProfuse watery diarrheaDehydrationDiminish the activity of lactase
Detection of antigen of Rotavirus in fecesImmunoassay quick testElectrophoresis of RNA from genome viralStaining with silver nitrateImmunosobernt assay
There is not a specific treatmentNon- suspend feedingTo change at soy formulaOral rehydrationNON-ANTIBIOTICS
To change at soy formulaSoy with fiber for 5 daysOnly soy for 15 daysComeback to habitual milk
Oral rehydration100 – 120 ml/kg/during 6 hours in low or
absent dehydration120 ml/kg/during 6 hours in moderate
dehydrationIV rehydration in severe dehydration
NON-ANTIBIOTICSAminoglycosides
Lactase deficiency aggravatesDiarrhea aggravatesIncrease the anxiety of familyIncrease needed of hospitalization
Thank you