unit i intra-cytoplasmic - altius hospital · ivf icsi has revolutionized the treatment of male...
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ALTIUS HOSPITAL PVT LTD
(Unit of Dr. Ramesh Hospital)
Success rates for ICSI:
Fertilization rates for ICSI: Most IVF programs see that about 70-85% of eggs injected using ICSI become fertilized. We call this the fertilization rate, which is different from the pregnancy success rate.
Pregnancy success rates for in vitro fertilization procedures with ICSI have been shown in some studies to be higher than for IVF without ICSI. This is because in many of the cases needing ICSI the female is relatively young and fertile (good egg quantity and quality) as compared to some of the women having IVF for other reasons.
What are the advantages of ICSI?
ICSI may give you and your partner a chance of conceiving your genetic child when other fertility treatments options are unlikely to do so.
If your partner is unable to ejaculate on the day of egg collection for standard IVF, sperm can instead be extracted for ICSI.
ICSI can also be used to help some couples with unexplained infertility. In this case however, your doctor is likely to initially recommend standard IVF, as ICSI and IVF pregnancy rates are very similar and IVF is a less complex treatment.
ICSI doesn't appear to have any effect on your child’s mental or physical development.
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Intra-cytoplasmIc sperm InjectIon
(IcsI)
Intra-Cytoplasmic Sperm Injection (ICSI)
What is intra-cytoplasmic sperm injection and how does it work ?
Used with IVF and eggs of good quality, ICSI often is a successful treatment for men with impaired or no sperm.
IVF ICSI has revolutionized the treatment of male infertility allowing fertilization to occur even if only a few sperms are available. First developed by reproductive medical specialists in Belgium, ICSI is a specialized form of microinsemination to help couples overcome male infertility problems. ICSI has become so successful that most treatments previously used for male infertility have been abandoned in its favour.
ICSI is often recommended if:
The male partner has a very low sperm count. Other problems with the sperm have been identified,
such as poor morphology (abnormally shaped) and/or poor motility (poor swimmers).
At previous attempts at in vitro fertilization (IVF) there was either failure of fertilization or an unexpectedly low fertilization rate.
The male partner has had a vasectomy and sperms have been collected from the testicles or epididymis (sperm reservoir).
Other situations where the sperm count is zero and donor insemination is not wanted.
The male partner does not ejaculate any sperm but sperm have been collected from the testicles.
The male partner has had problems obtaining an erection and ejaculating. This includes men with spinal cord injuries, diabetes and other disorders.
How does ICSI work?
The procedure for ICSI is similar to that for IVF(see IVF patient information leaflet), but instead of fertilization taking place in a dish, the embryologist selects sperm from the sample and a single sperm is injected directly into each egg. After two to three days in the laboratory, those that are fertilized are transferred to your womb in the same way as for conventional IVF.
The major development of ICSI means that as long as some sperm can be obtained (even in very low numbers), fertilization is possible.
This procedure requires highly developed skills. Because only one sperm is needed per egg, even very small number of sperms can work. This becomes especially important in males with azoospermia (the complete lack of sperm present in the ejaculate). In such cases, we can offer a procedure called testicular sperm extraction (TESE), where
our doctor extracts a small piece of testicular tissue that may contain sperm cells that can be used for ICSI. In a very high percentage of cases, azoospermic males can achieve fatherhood.
Difference between IVF and ICSI ?
During routine IVF, eggs and sperm are combined and incubated together in order to achieve fertilization. ICSI is performed by the embryologist, who surgically inserts one sperm into each egg. This is done by perforating the membrane of the egg with a glass pipette, which contains the sperm.