Tue, Feb 2, 2016 CURRICULUM VITA

William Frederick Jackson Department of Pharmacology and Toxicology

Michigan State University 1355 Bogue Street, Room B429 Life Sciences

East Lansing, Michigan 48824 Phone: (517) 353-5476

Email: jacks783@msu.edu Personal Home address: 4020 Shoals Dr. Okemos, Michigan 48864 (517) 347-6468 Social Security: available on request Date of birth: November 18, 1952 Place of birth: Detroit, MI Citizenship: U.S. Family: Debra Ellen-Budde Jackson (wife) William Carl Jackson, M.D. (son) Jeffrey Donald Jackson (son) Scott Alexander Jackson (son) Education

1970-1974 Michigan State University, B.S., Zoology. Major areas: General zoology, mathematics and German.

1974-1976 Michigan State University, M.S., Physiology. Major areas: Comparative physiology, and

environmental toxicology. Thesis title: Effects of Linear Alkylate Sulphonate on Tritiated Water Uptake by Isolated Perfused Gills of Rainbow Trout. Advisor: Paul O. Fromm, Ph.D.

1976-1979 Michigan State University, Ph.D., Physiology. Major areas: Comparative physiology and

cardiovascular physiology. Dissertation title: Physical and Biological Factors Affecting the Movement of Water Across Isolated Perfused Fish Gills. Advisor: Paul O. Fromm, Ph.D.

1977-1980 Michigan State University, M.S., Applied Mathematics. Major areas: Compartmental

analysis and fluid mechanics. Advisor: C.Y. Wang, Ph.D. 1979-1980 Michigan State University, Postdoctoral Trainee. Research topics: Effects of vasodilators

on skeletal muscle oxygen consumption and distribution of blood flow, and the role of oxygen in control of fish gill vascular resistance. Supervisors: Jerry B. Scott, Ph.D. and Paul O. Fromm, Ph.D.

1980-1983 University of Virginia, Postdoctoral Fellow. Research topic: Role of Oxygen in Control

of Microvessel Function. Supervisor: Brian R. Duling, Ph.D.

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Academic Appointments 1980-1981 Piedmont Virginia Community College, Instructor. 1983-1989 Medical College of Georgia, School of Medicine, Assistant Professor. 1984-1989 Medical College of Georgia, School of Graduate Studies, Assistant Professor. 1989 Medical College of Georgia, School of Medicine, Associate Professor with tenure. 1989 Medical College of Georgia, School of Graduate Studies, Associate Professor with

tenure. 1989-1993 Western Michigan University, College of Arts and Sciences, Associate Professor. 1993-1994 Western Michigan University, College of Arts and Sciences, Associate Professor with

tenure. 1995 Medical College of Wisconsin, Dept. of Physiology, Visiting Professor 1994-2005 Western Michigan University, College of Arts and Sciences, Professor with tenure. 1994-1995 Western Michigan University, Director, Center for Research in Environmental Signal

Transduction. 2005- Michigan State University, Dept. of Pharmacology & Toxicology, Professor with tenure,

Director of PSM in Integrative Pharmacology. 2011-2013 Michigan State University, Dept. of Pharmacology & Toxicology, Associate Chair and

Acting/Interim Chair. 2015 University of Vermont, Dept. of Pharmacology, Visiting Professor

Funded Research Grants (Direct Costs Only)

1984-1987 National Institutes of Health, New Investigator Research Award, "Control of Microvascular Function by Oxygen" ($107,500).

1987-1992 National Institutes of Health, "Control of Microvascular Function by Oxygen" ($368,469).

1988-1989 National Institutes of Health, "Development of the Heart: Role of the Neural Crest", Margaret Kirby, Program Director, Project 3 - Hemodynamics of Heart Development, William F. Jackson, P.I. (total budget, Project 3, $210,389).

1988-1989 National Institutes of Health, "Elastic Artery Development and Congenital Heart Defects" (T. Rosenquist, PI, W.F. Jackson, Co-Investigator) ($579,041).

1989-1990 National Institutes of Health, "Elastic Artery Development and Congenital Heart Defects" (T. Rosenquist, PI, W.F. Jackson, Consultant) ($579,041).

1989-1994 NATO Cooperative Research Grant - "Release of EDRF from Arterioles" ($9,840: Budget for 1992-1993 = $3,455).

1992-1997 National Institutes of Health, "Control of Microvascular Function by Oxygen" ($403,018).

1995 National Institutes of Health, National Research Service Award, Senior Postdoctoral Fellowship, K+-Channels and Arteriolar Hyperpolarization - $10,769 (Partial salary support for 4 months)

1997-2002 National Institutes of Health, "Control of Microvascular Function by Oxygen" ($372,694).

2002-2008 National Institutes of Health, "Control of Microvascular Function by Oxygen" ($700,000) 2007-2014 National Institutes of Health, “Microcirculation in Aging Skeletal Muscle” ($1,934,108) 2008-2015 National Institutes of Health, “Neurohumoral Control of Veins in Hypertension”,

Director, Core D, Imaging and Cell Biology Core. 2015-2020 National Institutes of Health, “Neurohumoral Control of Veins in Obesity-associated

Hypertension”, Director, Core D, Imaging and Cell Biology Core, Co-I on Project 3.

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Teaching Michigan State University Comparative Physiology (PSL 401) 1974-1979 Teaching Assistant (Taught laboratories) Human Physiology (PSL 431) 1978-1979 Teaching Assistant (Ran Review sessions) Piedmont Virginia Community College Human Anatomy and Physiology (NASC 111 and 112) 1980-1981 Instructor (Lecture and Laboratory) Medical College of Georgia Medical Physiology I (PHY 550) 1983-1984 Conference Leader 1984-1985 Lecturer (Reflexes, and Autonomic Nervous System) 1985-1986 Conference Leader 1986-1989 Lecturer (Cardiovascular Physiology) 1987-1989 Conference Leader and Tutorial Lecturer Medical Physiology II (PHY 551) 1984 Conference Leader 1986-1989 Lecturer (Cardiovascular Effects of Exercise) Introduction to Physiology (PHY 200) 1984-1985 Lecturer (Cell, Neural, Muscle and Gastrointestinal Physiology) 1985-1986 Course Director and Lecturer (Cardiovascular, Neural and Respiratory Physiology) Muscle Physiology (PHY 804) 1985-1986 Lecturer (Smooth Muscle Physiology) Consequences of Receptor Activation (Pharmacology 804) 1985-1986 Lecturer (Guanylate Cyclase) Endothelial Cell Smooth Muscle Interactions (Physiology 899) 1985-1986 Course Director Principles of Biological Regulation (Physiology and Endocrinology 707) 1987-1989 Lecturer (Endothelium and Regulation of Blood Flow) Peripheral Circulation (Physiology 803) 1987-1988 Course Director Western Michigan University Clinical Physiology (BIOS 321) 1989-1997 Course Director and Sole Instructor Human Physiology (BIOS 350) 1993-1994 Lecturer (Nerve, Muscle, Cardiovasc., Respir., and Renal Physiology) 1997 Co-Director (all Lectures) 1998-2004 Course Director Applied Biostatistics or Experimental Design (BIOS 633) 1990-2002 Course Director Comparative Physiology (BIOS 577) or Animal Physiology (613) 1990-1995 Course Director Physiology and Pharmacology of Blood Vessels (BIOS 602) 1991-1992 Course Director

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Teaching - Western Michigan University (Continued) Principles of Pharmacology (BIOS 599 or BIOS 561) 1992-1993 Course Director 2000-2001 Course Director Senior Seminar (BIOS 497/597) 1998, 2001, 2003 Cell-Cell Communication, Course Director 1999 Ion Channels in Health and Disease, Course Director Michigan State University Integrative Pharmacology and Toxicology Short Course 2005-2013 Lecturer, Laboratory Instructor Physiology and Pharmacology of Excitable Cells (PHM 827) 2005 - 2014 Lecturer – Calcium regulation, Smooth Muscle and Cardiac Electrophysiology Cardiovascular Pharmacology (PHM 813) 2005, 2008 Lecturer – Microvascular Physiology and Pharmacology 2013 - 2015 Course Director and Online Instructor Experimental Design and Data Analysis (PHM 830) 2007 - 2015 Course Director and Online Instructor Applied Integrative Pharmacology Lab (PHM 832) 2009 - 2015 Course Director and Instructor Students Supervised: 1990-1995 Nancy Stratman, Graduate Student, MS, 1995 1990-1994 Martha Babbit, MS 1994 1991-1993 Brian Curry, Graduate Student - MS, 1993 1991-1994 Mike Smith, Graduate Student - MS, 1994 1994 Tom Schermerhorn, Graduate Student 1994-1995 Stacey Leva, Honors Thesis Advisor 1995-1997 James Curry, Graduate Student - MS 1997 1995 Chartier Aimone, Undergraduate Student 1996 Michael Bodman, Kalamazoo College, Student Individualized Project 1997-1998 Aksana Ajayi, Graduate Student - MS 1998 1997-1998 Matthew Noble, Undergraduate Student 1997 Nathan Dymond, Honors Thesis Advisor 1997 Kathleen Bortell, Honors Thesis Advisor 1997-1998 Lauren Fitch, Undergraduate Student 1998 Zak Lloyd, Undergraduate Student 1998 Henry Barff, Undergraduate Student 1998,99 Aaron Ford, Undergraduate Student 1998-2003 Wendy Burns, Ph.D. 2003.

1998-2006 Prentice Jones, Ph.D. (Co-chair with Dr. Ken Olson, Notre Dame), Ph.D. 2006. 1999-2000 Scott Pinchot, Honor Thesis Advisor.

1999 Mary Slominis, Undergraduate student. 1999 Bill Chopp, Undergraduate student.

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Students Supervised (continued): 1999-2000 Mianda Carr, Honors Thesis Advisor. 1999 Tashara Jones, Undergraduate Student 2000-2004 Kenneth Cohen, Ph.D., Postdoctoral Fellow (AHA Postdoc. Fellowship) 2000 Samuel Rodriguez, Undergraduate Student (NIH Bridges fellow) 2001 Angela Bonner, Undergraduate Student. 2001-2002 Zak Lloyd, Graduate Student 2001-2002 Michelle Suppnick, Honors Thesis Advisor

2002-2003 Andrew Powers, Honors Thesis Advisor 2003 Amy Kleinfehn, NSF REU undergraduate student 2004 Stephanie Ford, undergraduate student 2004-2005 Dan Hillary, undergraduate student 2006-2011 Erika Boerman Westcott, Ph.D. 2010 (AHA Predoc. Fellow), and postdoc. 2010-11. 2006-2012 Nathan Tycocki, undergraduate student, graduate student; Ph.D., 2012 2008-2010 Erica Lange, graduate student, PSM Integrative Pharmacology, 2010. 2008-2010 Brian Jespersen, graduate student, PSM Integrative Pharmacology, 2010. 2011-2014 Sebastien Hayoz, Ph.D. – Postdoctoral Fellow 2011-2014 Alice Stack, DVM, graduate student Ph.D., 2014 2012 Vanessa Bradley, CVM student summer research fellow (DVM student) 2013-2015 Jessica Pettis, CVM student summer research fellow (Undergraduate) 2014-2016 Brendan Mullan, Undergraduate Research Assistant 2014 Chantelle Washington, CVM student summer research fellow (Undergraduate) 2015 Sumira Stein, REPID Summer Research Scholar (Medical Student) Thesis Committees: (23 total, current are listed) Daniel Kueh (Advisors: Jellies, WMU) – Ph.D., WMU June 2012 Nathan Tykocki (Advisors: Watts and Jackson, Co-mentors), Ph.D., MSU August 2012. Carla Dam (Advisor; Anne Dorrance) – MS, 2012 Alice Stack (Advisor: Fred Dirksen; Research Performed in Jackson Lab, PhD. August 2014) Nusrat Matin (Advisor: Anne Dorrance) Janice M. Diaz-Otero (Advisor: Anne Dorrance) Nadia Ayala (Advisor: Watts) Service Departmental Committee Assignments Western Michigan University 1989-93, ’99-01 Curriculum Committee (Chair, 2000-2001) 1989-1993 Doctoral Program Committee (Chair, 1990-1993) 1990-92, ’94-’98, ’01-03 Advisory Committee 1991-93, ’94-‘95 Merit Committee (Chair, 1992) 1993-1995 Ph.D. Implementation Committee 1993-1994 Microbiologist Search Committee 1994-1996 Neurobiologist Search Committee 1997 Physiologist/Toxicologist Search Committee (Chair) 1997-2001 Association of Minorities in Biological Sciences, Faculty Advisor 1995-2004 Pre-professional Advisor for Athletic Recruits 2003-2004 Cell Biologist Search Committee (Chair) 1998-2000 Physiologist Search Committee

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Service (continued) Departmental Committee Assignments (Continued) Michigan State University 2005-2006 Graduate Student Selection Committee 2005-2007 Curriculum Committee (Co-Chair, 2006-2007) 2007-2015 Online Education and Admissions committee (Chair) 2014-2016 Faculty Advisory Committee Institutional Committee Assignments Medical College of Georgia 1984-1988 Faculty Senate 1985 School of Medicine, Faculty Appointments, Promotions and Tenure Committee 1985-1987 Faculty Affairs Committee (Chairman Faculty Recognition subcommittee, 1986) 1985-1986 School of Medicine, Distinguished Visiting Scientist Committee

1986-1989 Academic Council, Faculty Appointments, Development, Promotions and Tenure Committee (Chairman, Tenure Subcommittee, 1987-1988; Chairman, Development Subcommittee, 1989)

1986-1988 Academic Council. 1987-1988 School of Graduate Studies, Judge, Graduate Student Research Committee 1987-1989 School of Graduate Studies, Faculty Affairs Committee (Chairman, 1989) 1988-1989 School of Graduate Studies, Nominating Committee

1988-1989 School of Medicine, Student Research Committee Western Michigan University 1990-1991 Ad Hoc Committee on Animal Use and Facilities 1992-1994 Faculty Senate Library Committee 1992-1995 Physician Assistant Student Selection Committee 1997-1998 Arts and Sciences Faculty Council 1999 Vice President for Information Services Search Committee 2000-2004 Distinguished Faculty Scholar Selection Committee Michigan State University 2010-2011 College of Osteopathic Medicine, College Advisory Committee Societal Committee Assignments 1984-1987; 2015-2018 Microcirculatory Soc., Awards Committee 1995-1998; 2008-2012 Microcirculatory Soc., Executive Council 1997-2000 Microcirculatory Soc., Publications Committee 2001-2004 Microcirculatory Soc., Finance Committee

2002-2004 Microcirculatory Soc., Programming Committee (Chair) 2010-2015 Microcirculatory Soc., Long Range Planning Committee 2011-2013 Microcirculatory Soc., International Liason Committee

2003-2005 Am. Physiological Society, Education Committee 2004-2005 Am. Physiological Society, Joint Programming Committee (Ed. Com. representative) 2008-2012 Am. Physiological Society, Joint Programming Committee (CV section) 2013-2016 Am. Physiological Society, Cardiovascular Section, Executive Committee and

Committee on Committees Rep.

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Societal Committee Assignments (Continued) 2011-2015 ASPET – Graduate Education Committee (Co-Chair, 2013-2014)

2009-2014 National Directors of Graduate Studies – Organizing Committee (Chair 2012) and Programming Committee (Co-Chair 2012)

2013-2016 Microcirculation, Joint Publications Committee (Chair) Community Service 1987-1989 Montclair Subdivision, Board of Governors 1989 CSRA Swim League, Treasurer 1990-2000 Portage AYSO and West Michigan Soccer Club, assistant coach ('90-'91, ‘92-’93, 93’-

‘94), head coach ('91-'92, ‘92-’93, ‘93-’94, ‘97-’98, '98-'99, '99-'00) 1994 E & D Soccer Coaching License, Michigan Youth Soccer Association 1996-1997 Soccer Zone West, Head Coach, U11B 1995-2004 Portage Soccer Club (Head coach U-10B '95-'96, Asst. Coach U12A '97-'98, Head coach

U16A '99, Head Coach U17A '00, U15-19A ’01-‘04, U12-13B ’02-‘04) 1995-2012 Portage Soccer Classic, Portage, Michigan (Operations, Scoring and Field Marshall) Editorial and Review Responsibilities

1983-2016 American Journal of Physiology, invited reviewer ‘83-’95, Editorial Board ‘95-’98, '01-'05, ’06-‘16.

1985-1987 MCG Research Institute, small grants program, invited reviewer. 1987-2014 Journal of Pharmacology and Experimental Therapeutics, invited reviewer. 1987-1989 American Heart Association, Georgia Affiliate, Research Peer Review

Committee. 1988-2002 Pflügers Archiv/European Journal of Physiology, invited reviewer. 1990-1993 American Heart Association, Michigan Affiliate, Research Peer Review

Committee. 1990-1994 National Institutes of Health, Clinical Sciences 2 Study Section, (Ad Hoc ‘90-92,

Full Member ‘92-94, Acting Chairman Feb. ‘94; Chairman, ‘94) 1991-2016 Journal of Vascular Research, invited reviewer ‘91-’94, Editorial Board ‘95-’16, 1991 NATO, Collaborative Research Grants, invited reviewer. 1991 Proc. Nat. Acad. Sci. (U.S.A.), invited reviewer. 1993-2014 Journal of Applied Physiology, invited reviewer. 1993-2015 Hypertension, invited reviewer 1993-2014 Journal of Cardiovascular Pharmacology, invited reviewer. 1994, ’98-,00, ‘02, 2003-2007 National Institutes of Health, Exp. Cardiovasc. Sci. Study Section, Ad Hoc

reviewer, Vascular Cell and Molecular Biology - full member ’03-‘07. 1994-1997 American Heart Association, Michigan Affiliate, Research Forum Committee.

1994-1996 Medical Research Council, England, invited reviewer. 1994 Veterans Administration Merit Review, invited reviewer.

1995-2014 Journal of Physiology, invited reviewer. 1994-2014 Circulation Research, invited reviewer ’94-2012, Editorial Board ’07-‘09. 1994-2015 Cardiovascular Research, invited reviewer. 1996 Life Sciences, invited reviewer. 1999-2001 American Heart Association, Great American Peer Review Committee 5C 1996-2000 American Heart Association, Cardiovascular Regulation II Study Section. 1996-2015 Microcirculation, invited reviewer '96-'97, Assoc. Editor '99-'04, Editor ’04-’09,

Consulting Editor, ’09-’15. 1996-2000 British Journal of Pharmacology, invited reviewer.

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Editorial and Review Responsibilities (continued) 1999-2002 Journal of General Pharmacology, invited reviewer. 2001 Physics in Medicine and Biology, invited reviewer. 2001-2015 Journal of Investigative Surgery, Editorial Board. 2002-2005 American Heart Association, Cardiovascular Regulation I Peer Review

Committee. 2002 Vascular Pharmacology, invited reviewer. 2002 Drugs, invited reviewer, invited reviewer. 2001 Canadian Journal of Applied Physiology, invited reviewer. 2012 Canadian Journal of Physiology and Pharmacology

2002 American Journal of Hypertension, invited reviewer 2003-2011 Journal of Cerebral Blood Flow and Metabolism, invited reviewer 2008 National Institutes of Health, Special Emphasis Panel, Electrical Signaling, Ion

Transport and Arrhythmias (ESTA) Study Section 2008 National Institutes of Health, Hypertension and Microcirculation Study Section,

chair and reviewer, Asynchronous Enhanced Discussion (AED). 2008-2010 National Institutes of Health, ad hoc reviewer for Program Projects. 2012 American Heart Association, Cardiac Electrophys. 1 Res Peer Review Committee 2012 Acta Physiologica Scandinavica, Invited reviewer 2005-2012 Arteriosclerosis, Thrombosis, and Vascular Biology, invited reviewer

Awards/Honors

1974 Michigan State University, Bachelor of Science with honor, Zoology. 1978 Michigan State University, Graduate Office Scholarship. 1981-1983 National Institutes of Health, National Research Service Award, Individual Postdoctoral

Fellowship. 1984-1987 National Institutes of Health, New Investigator Research Award. 1986-1987 Microcirculatory Society, Inc., Pharmacia Travel Award. 1987 Medical College of Georgia, School of Medicine, Outstanding Young Faculty Award,

Basic Sciences. 1994 National Institutes of Health, Chairman, Clinical Sciences 2 study Section. 1995-2015 Journal of Vascular Research, Editorial Board 1995-98 & 2001-2015 American Journal of Physiology, Heart and Circulatory Physiology, Editorial Board. 1995 American Physiological Society, Fellow of the Cardiovascular Section. 1995 National Institutes of Health, National Research Service Award, Senior Postdoctoral

Fellowship 1996 WMU, College of Arts and Sciences, Dean’s Appreciation Award. 1997 WMU, Presidential Stipend. 1998 WMU, Distinguished Faculty Scholar Award. 1999-2004 Microcirculation, Associate Editor. 1999 Michigan State University, Department of Physiology, 1st CC. Chou Endowed Lecture 2001-2015 Journal of Investigative Surgery, Editorial Board. 2004-2009 Microcirculation, Editor-in-Chief 2010-2015 Microcirculation, Consulting Editor 2007-2009 Circulation Research, Editorial Board. 2008-2011 Microcirculatory Society, Inc., President-elect, President, past-President 2014 Fellow of the American Heart Association – High Blood Pressure Council

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Invited Lectures 1986 University of South Carolina, Department of Physiology.

1986 University of Birmingham, Birmingham, U.K., Department of Physiology. 1986 University of Wales, Cardiff, Wales, U.K., Depts. of Radiology and Cardiology.

1986 Karolinska Institute, Stockholm, Sweden, Department of Physiology. 1986 University of Lund, Lund, Sweden, Department of Physiology and Biophysics. 1986, ‘89 & ’93 Univ. of Freiburg, Freiburg, Germany, Dept. of App. Physiology, Visiting Scientist. 1986 Free University of Berlin, Berlin, Germany, Dept. of Physiology.

1987 Oxygen Transport and Regulation in the Microcirculation Symposium, Washington, D.C. 1987 University of Virginia, Department of Physiology, Visiting Scientist. 1989 Western Michigan University, Dept. of Biological Sciences. 1989 Kalamazoo College, Dept. of Biology.

1990 Calvin College, Dept. of Biology 1990 Vascular Cell Biology Gordon Research Conference, Meriden, NH.

1991 University of Cincinnati School of Medicine, Dept. of Plastic, Reconstructive and Hand Surgery. 1991 Medical University of Lübeck, Lübeck, Germany, Institute for Physiology. 1991 Third International Symposium on Resistance Arteries, Rebild, Denmark. 1991 FASEB Summer Conference: Endothelium and Cardiovascular Function, Copper Mountain, CO. 1992 Penn. State University, Dept. of Exercise and Sports Sciences. 1992 The Upjohn Company, Div. of Cardiovascular Research, Visiting Scientist and invited speaker. 1992 Univ. Texas Health Sci. Center, San Antonio, Dept. of Pharmacology. 1992 Texas A&M University, Dept. of Medical Physiology. 1992 17th European Conference on Microcirculation, London, England. 1993 University of Virginia, Dept. of Molecular Physiology and Biological Physics. 1993 Microcirculatory Soc. Annual Meeting, New Orleans, LA, Session Chair. 1993 Michigan Society for Respiratory Care, Annual Meeting, Dearborn, MI. 1993 Mechanisms of Vasodilatation, I.U.P.S. International Congress, Glasgow, Scotland, U.K.. 1993 Western Michigan University, Physician Assistant Commencement, Keynote Speaker. 1994 Exp. Biology ‘94, Anaheim, CA, APS Career Opportunities Symposium. 1994 University of Mississippi Medical Center, Dept. of Physiology and Biophysics. 1995 John B. Pierce Foundation at Yale University, New Haven, Connecticut. 1995 Medical College of Wisconsin, Milwaukee, WI, Dept. of Physiology, Visiting Professor. 1995 American College of Sports Medicine, Oxygen Transport Symposium, Indianapolis, IN. 1995 Wolfgang Goethe University, Frankfurt, Germany , Institute for Physiology, Visiting Scientist. 1996 FASEB Summer Conference, Copper Mountain, CO, Splanchnic Circulation. 1996 University of Mainz, Mainz, Germany, Institute for Physiology. 1996 6th World Congress on Microcirculation, Munich, Germany, poster discussant. 1997 Vascular Biology ‘97, New Orleans, LA, Microcirculatory Soc., Inc., President’s symposium. 1997 British Microcirculatory Society, Birmingham, U.K., Symposium on cellular mechanisms

underlying control of the microcirculation. 1998 Yale University, Dept. of Molecular Physiology and Biophysics. 1999 New York Medical College, Dept. of Pharmacology. 1998 Henry Ford Hospital, Detroit, MI, Division of Hypertension and Vascular Research. 1998 FASEB Summer Conference, Namaste, OR, Splanchnic Circulation. 1998 20th European Conference on Microcirculation, Paris, France. 1999 University of Missouri, Department of Physiology. 1999 Michigan State University, Department of Physiology. 1999 University of Virginia, Cardiovascular Research Center. 1999 American Heart Association, Council on High Blood Pressure, Ion Channel Workshop.

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Invited Lectures (continued) 1999 Oakland University, Dept. of Biological Sciences. 2000 Texas A&M University, Department of Medical Physiology 2000 Michigan State University. Department of Medicine. 2000 FASEB Summer Conference, Snowmass, CO, Smooth Muscle. 2000 University of Vermont, Department of Pharmacology. 2000 University of Frankfurt, Institute for Physiology. 2001 Experimental Biology 2001 - Featured Topic organizer and Speaker. 2001 World Microcirculation Congress, Sydney Australia. Plenary lecturer, Symposium Organizer

and Speaker. 2001 John B. Pierce Foundation and Yale University, Visiting Scientist. 2001 University of South Alabama, Department of Physiology, Distinguished Scientist Seminar

speaker. 2002 Hope College, Dept. of Biology, invited lecturer. 2002 Loma Linda University, Center for Perinatal Biology, Visiting Scientist. 2003 Louisiana State University Health Sciences Center, Dept. of Molecular and Cellular Physiology,

invited Seminar Speaker. 2003 Calvin College, Dept. of Biology, Invited Seminar Speaker 2003 University of Frankfurt, Institute for Physiology, Invited Seminar Speaker 2003 Gesellshaft für Mikrozirkulation und Vasculär Biologie, Munich Germany, Invited Symposium

Speaker and Session Chair. 2004 Microcirculatory Society, Inc., 50th Anniversary Symposium Organizer/Speaker. 2004 LSU Health Sciences Center, New Orleans, Dept. of Physiology, Invited Seminar Speaker 2004 Michigan State University, Dept. of Pharmacology & Toxicology, Invited Seminar Speaker 2005 John B. Pierce Foundation and Yale University, Visiting Scientist 2005 Medical College of Wisconsin, Dept. of Pharmacology, Invited Seminar Speaker and lecturer 2006 University of Vermont, Dept. of Pharmacology, Invited Seminar Speaker. 2006 FASEB Summer Conference on Smooth Muscle, Snowmass, CO, Invited Speaker. 2006 ACSM, Integrative Physiology of Exercise Conference, Indianapolis, IN, Invited Speaker. 2007 University of Missouri, Dept. of Medical Physiology and Pharmacology, Invited Seminar

Speaker. 2007 The Physiological Society: Focused Meeting on Ion Channels in the Microcirculation, Belfast,

Ireland, Invited Speaker. 2007 Cardiovascular Institute, Loyola University, Chicago, IL, Invited Seminar Speaker. 2007 8th World Congress for Microcirculation, Milwaukee, WI, Invited Symposium Speaker. 2007 University of South Alabama, College of Medicine, Distinguished Scientist Seminar Speaker. 2007 Ohio Physiological Society, Athens Ohio, Invited Speaker, Feature Lecture. 2008 9th International Symposium on Resistance Arteries, Hamilton Island, Australia, Invited Speaker 2008 University of Illinois, Chicago, Dept. Pulmonary and Critical Care Medicine, Seminar Speaker. 2008 University of Virginia, Cardiovascualr Research Center, Invited Seminar Speaker 2009 Keystone Symposia: Dissecting the Vasculature. Vancouver, B.C., Canada, Co-organizer and

invited speaker. 2010 University of Arkansas, Dept. of Pharmacology, Invited Seminar Speaker 2010 Experimental Biology 2010, The Microcirculatory Society, President’s Symposium, Organizer

and invited Speaker. 2010 9th World Congress for Microcirculation, Paris, Fr., Symposium organizer and Invited Speaker 2011 10th International Symposium on Resistance Arteries, Rebild, Denmark, Invited Speaker 2011 Joint Meeting of the European Society of Microcirculation (ESM) and Society of

Microcirculation and Vascular Biology (GfMVB) – Symposium Organizer and Invited Speaker.

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Invited Lectures (continued) 2012 British Microcirculation Society Annual Meeting, Oxford, UK – Symposium Chair 2012 Department of Physiology and Anatomy, Kansas State University, Invited Speaker 2013 Department of Cellular and Molecular Physiology, Univ. of Liverpool, UK - Invited Speaker 2013 Department of Biological Sciences, Bowling Green State University – Invited Speaker 2014 Department of Pharmacology, University of Vermont – Invited Speaker

Scientific and Professional Societies American Physiological Society American Heart Association, Council on Circulation and High Blood Pressure Council Microcirculatory Society, Inc. North American Vascular Biology Organization American Society for Pharmacology and Experimental Therapeutics Abstracts 1) Jackson, W.F. and P.O. Fromm. Effects of linear alkylate sulphonate on tritiated water uptake by isolated perfused gills of rainbow trout. The Physiologist. 19: 239, 1976. 2) Jackson, W.F. and P.O. Fromm. A model of gill water exchange. Am. Zool. 19: 893, 1977. 3) Jackson, W.F. and P.O. Fromm. Water exchange across fish gills. The Physiologist. 21: 59, 1978. 4) Jackson, W.F. and P.O. Fromm. Boundary layers and diffusion across trout (Salmo gairdneri) gills. The Physiologist. 22: 62, 1979. 5) Jackson, W.F. and P.O. Fromm. Intrinsic hypoxic vasoconstriction in saline perfused trout gills (Salmo gairdneri). The Physiologist. 23: 175, 1980. 6) Jackson, W.F. and B.R. Duling. A test of the oxygen sensitivity of arterioles in the suffused hamster cheek pouch. The Physiologist. 25: 194, 1982. 7) Jackson, W.F. and B.R. Duling. Arteriolar reactivity to oxygen in situ and in vitro: Relation to local flow control. Fed. Proc. 42(5): 1348, 1983. 8) Jackson, W.F. Lack of influence of indomethacin on arteriolar oxygen reactivity. Int. J. Microcirc.: Clin. Exp. 3: 330, 1984. 9) Duling, B.R., W.F. Jackson and R.L. Hester. Is the vessel wall both sensor and effector in local control of blood flow? Int. J. Microcirc.: Clin. Exp. 3: 517, 1984. 10) Jackson, W.F. Is phospholipase A2 involved in arteriolar O2 reactivity? Microvascular Research 29: 228, 1985. 11) Jackson, W.F. Agonist-induced rhythmic contractions of hamster aortas are endothelium-dependent, Fed. Proc. 45: 560, 1986. 12) Jackson, W.F. Lipoxygenase inhibitors decrease arteriolar O2 reactivity. Blood Vessels 23: 79, 1986.

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Abstracts (continued) 13) Jackson, W.F. Arteriolar oxygen reactivity: Where is the sensor located? Proc. Int. Union Physiol. Sci. XVI: 340, 1986. 14) Jackson, W.F., U. Pohl and R. Busse. Endothelium-dependent oxygen reactivity in hamster carotid arteries. Fed. Proc. 46: 1530, 1987. 15) Jackson, W.F. Species differences in the effects of inhibitors of endothelium-dependent relaxation. Fed. Proc. 46: 827, 1987. 16) Jackson, W.F. Do leukotrienes mediate arteriolar O2 responses? FASEB J. 2: A1868, 1988. 17) Jackson, W.F. Endothelium-dependent responses to Ca++ in hamster aortas. FASEB J. 3: A1176, 1989. 18) Jackson, W.F. and J.R. Searle. An affordable video caliper. FASEB J. 3: A1390, 1989. 19) Jackson, W.F. Endothelium-dependent responses to nitrovasodilators and 8-bromo-cyclic guanosine monophosphate in hamster aortas. J. Vasc. Med. Biol. 1(3): 182, 1989. 20) Jackson, W.F. Endothelium-dependent O2 reactivity in hamster aortas. Proc. Int. Union. Physiol. Sci. XVII: 165, 1989. 21) Jackson, W.F. Is there an arteriolar endothelial cell oxygen sensor in vivo? in Vascular Endothelium: Receptors and Transduction Mechanisms, edited by J.D. Catravas, C.N. Gillis, and U.S. Ryan, Plenum Press, NY, 1989, p. 256. 22) Jackson, W.F., A. Mülsch and R. Busse. Nitric oxide mediates endothelium-dependent oscillations in hamster aortas. FASEB J. 4(3): A310, 1990. 23) Jackson, W.F. and P.W. Walsworth. NG-nitro-l-arginine inhibits vasomotion in hamster cheek pouch resistance vessels in vivo. Blood Vessels 28(4): 297-298, 1991. 24) Jackson, W.F. ATP-dependent potassium channels (K+

ATP) do not mediate hypoxic relaxation of hamster aortas. FASEB J. 5(4): A779, 1991. 25) Jackson, W.F. and P.W. Walsworth. ATP-sensitive potassium channel (K+

ATP) activity determines arteriolar tone and reactivity. Proc. 5th World Congress on Microcir., University of Louisviile Press, p. 43, 1991. 26) Jackson, W.F. Regional differences in the mechanism of action of oxygen on hamster arterioles. FASEB J., 6(5): A2076, 1992. 27) Jackson, W.F. Cellular basis of cyclic vasomotion in the vessel wall. Int. J. Microcirculation: Clin. Exp., 11(Suppl. 1): S69, 1992.

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Abstracts (continued) 28) Jackson, W.F., T.D. Tsai, and K.S. Lee. Glyburide sensitive K+ channels regulate membrane potential of dog coronary artery smooth muscle cells. Biophys. J. 64 (2,2): A310, 1993. 29) Jackson, W.F., A. König, T. Dambacher, and R. Busse. ATP-sensitive K+ channels mediate prostacyclin-induced coronary vasodilatation, Proc. Int. Union. Physiol. Sci XVIII: 73.11/0, 1993. 30) Jackson, W.F., A. König, T. Dambacher, and R. Busse. ATP-sensitive K+ channels mediate the prostacyclin-component of bradykinin-induced vasodilation in rabbit hearts. FASEB J., 7(4): A889, 1993. 31) Jackson, W.F., R. Busse and K.S. Lee. ATP-Sensitive K channel activity contributes to resistance artery and arteriolar tone. J. Vasc. Res. 31 (S1): 19, 1994. 32) Jackson, W.F. and M.D. Charlton. Isoproterenol dilates hamster mesenteric arteries by activating ATP-sensitive K+ channels. FASEB J. 8(5): A1045, 1994. 33) Curry, B.D. and W.F. Jackson. Nonspecific inhibition of vascular smooth muscle relaxation by cyclopiazonic acid and thapsigargin. FASEB J. 8(4): A31, 1994. 34) Jackson, W.F. and T.C. Schermerhorn. Enzymatic isolation and characterization of smooth muscle cells from hamster arterioles. Microcirculation 2(1): 91, 1995. 35) Schaefer, G.J., R.G. York, C.D. King,S.M. Miller, L.J. Beuving, W.F. Jackson, J.M. Huebner, and J.B. Terrill. The effects of ibogaine on clinical pathology, neuropathology and nerve conduction velocity in rabbits. Society for Neuroscience 21, 1728, 1995. 36) Jackson, W.F., K.L. Blair, and N.J. Rusch. Large Conductance, Ca++-activated K+ Channels in arteriolar smooth muscle cells have low Ca++-sensitivity. Microcirculation 3(1): 92, 1996. 37) Rusch, N.J., K. Gauthier-Rein, Y. Liu, C. Vandier, and W.F. Jackson. Regulation of membrane potential and diameter in small coronary arteries of human left ventricle by two K+ channel types. FASEB J. 10(3): A571, 1996. 38) C. Vandier, O. Dimsom, W.F. Jackson, P. Bonnet, and N.J. Rusch. Potassium current in pulmonary and coronary arterial smooth muscle cells is differentially regulated by NH4Cl-induced changes in intracellular pH. FASEB J. 10(3): A105, 1996. 39) Jackson, W.F. and N.J. Rusch. Voltage-activated and ATP-sensitive K+ channels regulate resting membrane potential in cremasteric arteriolar muscle cells. Int. J. Microcirc.: Clin. Exp. 16(S1): 258, 1996. 40) Jackson, W.F., D. Harder, R. Roman, J. Narayanan and J.H. Lombard. Cytochrome P-450 mediates arteriolar oxygen reactivity in hamster cremaster muscles. Int. J. Microcirc.: Clin. Exp. 16(S1): 145, 1996. 41) Jackson, W.F. and J.M. Huebner. Cremasteric arteriolar muscle cells are intrinsically sensitive to O2. Microcirculation 4(1): 159, 1997. 42) Curry, J.T., S.J. Humphrey, E.J. Jacobsen and W.F. Jackson. Water diuretic activity of PNU80873A, a novel phenylbutylamine, in conscious rats. FASEB J. 11(3):A460, 1997.

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Abstracts (continued) 43) Lombard, J.H., R.J. Roman, D.R. Harder and W.F. Jackson. Role of 20-HETE in mediating O2-induced constriction of arterioles in the hamster microcirculation. Microcirculation 4(1): 159, 1997. 44) Jackson, W.F. Potassium increases barium-sensitive potassium conductance of cremasteric arteriolar muscle cells. FASEB J. 12(4): A14, 1998. 45) Welsh, D.G., W.F. Jackson and S.S. Segal. Oxygen depolarizes smooth muscle cells in hamster cheek pouch arterioles : A role for L-type Ca2+ channels. FASEB J. 12(4): A388, 1998. 46) Berger, M.G., K. Gauthier-Rein, Y. Liu, W.F. Jackson, H. Guenther-Knaus and N.J. Rusch. Expression of two K+ channel families regulates the excitability of small coronary arteries from human left ventricle. Journal of the American College of Cardiology. 31(2), Suppl A: 1A, Abstract # 406-2. 47) Jackson, W.F. Potassium channels in the control of basal vascular tone. J. Vascular Res. 35(supp. 2): 17, 1998. 48) Jackson, W.F. Glibenclamide-sensitive oxygen reactivity in the absence of evidence for activation of ATP sensitive K+ channels. FASEB J. 13(4): A31, 1999. 49) Jackson, W.F. Cl- channel blockers dilate O2 constricted arterioles in the hamster cheek pouch. FASEB J 14(4): A31, #32.26, 2000. 50) Burns, W.R. and W.F. Jackson. K+-induced dilation of cremasteric arterioles is transient. FASEB J 14(4): A31, #32.27, 2000. 51) Cohen K.D. and W.F. Jackson. Norepinephrine-induced Ca2+ transients in arteriolar muscle cells. FASEB J 15(4): A49, #42.12, 2001. 52) Bukoski, R.D., S. Shearin, W.F. Jackson, M.F. Pamarthi. Inhibition of Ca2+-induced relaxation by oxidzed tungsten wires and paratungstate. Hypertension 38(3): 518, 2001. 53) Bukoski, R.D., S. Batkai, Z. Jarai, Y. Wang, W.F. Jackson, G. Kunos. The CB1 receptor antagonist SR141716A inhibits Ca2+-induced relaxation in CB1 receptor deficient mice. Possible role for a non-classical cannabanoid receptor? Hypertension 38(3): 509 ,2001. 54) Cohen, K.D. and W.F Jackson. Hypoxia does not inhibit norepinephrine-induced Ca2+ transients in arteriolar muscle cells. FASEB J, 16(4): Abstract 134.32, 2002. 55) Cohen, K.D. and W.F Jackson. Norepinephrine and phenylephrine increase [Ca2+]I of endothelium in arterioles but not of isolated arteriolar endothelial cells. FASEB J 17(1): A139, 2003 56) Jackson, W.F. Potassium-induced hyperpolarization of skeletal muscle arterioles requires active tone. FASEB J 17(1): A139, 2003. 57) Jackson, W.F. and K.D. Cohen. K+ channels in the microcirculation. J. Vasc. Res. 41(1): 92, 2004. 58) Cohen, K.D. and W.F Jackson. Membrane hyperpolarization is not required for sustained muscarinic receptor mediated increases in arteriolar endothelial cell Ca2+. FASEB J, 18(4), A251, 2004.

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Abstracts (continued) 59) Jackson W.F. and S.S. Segal. Cysteinyl leukotrienes depolarize arteriolar muscle cells and initiate conducted vasoconstriction. FASEB J 19(4): A722-A723, 2005. 60) Brekke , JF, Jackson, WF and Segal SS. Calcium dynamics in arteriolar smooth muscle cells during blood flow control. Microcirculation 12(8): 649, 2005. 61) Brekke , JF, Jackson, WF and Segal SS. Arteriolar smooth muscle calcium dynamics in hamster cheek pouch in vivo. FASEB J. 20: A273, 2006. 62) Jackson, WF. Functional activity of BKCa channels is not coupled to the activity of ryanodine receptors in hamster cheek pouch arterioles. FASEB J. 20: A270, 2006. 63) Boerman, E.M., Lundback S.M., Lange E.J., Jackson, W.F. Do TRPV channels contribute to myogenic tone in skeletal muscle arterioles? FASEB J. 21:740.14, 2007. 64) Hakim C., Jackson, W.F., and Segal, S.S. Connexin isoform expression in microvascular smooth muscle and endothelium. FASEB J. 21:898.1, 2007. 65) Jackson, W.F. Protein kinase C does not play a major role in myogenic tone in hamster cheek pouch areterioles, in vitro. Microcirculation 14(4-5): VR-31, 542-543, 2007. 66) Boerman, E.M., Tykocki, N.R. and Jackson, W.F. Ryanodine receptors and Ca2+-activated K+ channels are not coupled in the microcirculation. Hypertension, 50(4): e144, P253, 2007. 67) Jackson, W.F., Boerman, E.M. Lange E.J., Lundback S.M.. Smooth muscle α1D-adrenoreceptors mediate phenylephrine-induced endothelial Ca2+ transients in hamster cremaster arterioles. FASEB J. 22:1149.4, 2008. 68) Boerman, E.M., Jackson, W.F. Ca2+-activated K+ channels are controlled by Ca2+ influx through voltage-gated Ca2+ channels, not the release of Ca2+ through ryanodine receptors in arteriolar smooth muscle. FASEB J. 22:1142.2, 2008. 69) Tykocki, N.R., Jackson W.F., Watts, S.W. Do Different Ca entry mechanisms mediate Endothelin-1-induced contraction of rat aorta and vena cava? FASEB J. 22:744.15, 2008. 70) Tykocki, N.R., Jackson W.F., Watts, S.W. The Complex Roles of ETB Receptors in Mediating Venous Tone. Hypertension 52(4): e109, P247, 2008. 71) Boerman, E.M., Jackson, W.F.. IP3 receptors, but not ryanodine receptors mediate subsarcolemmal Ca2+ oscillations in arteriolar smooth muscle cells. FASEB J. 23:767.3, 2009 72) Boerman, E.M, Jackson, W.F. Regional Differences in the mechanisms of myogenic tone in the microcircualtion. Microcirculation 16(8) 763-764, 2009. 73) Socha, Mj.J. Hakim, C.H., Jackson, W.F., Segal, S.S. Temperature-dependent calcium signaling in microvascular endothelial tubes. Microcirculation 16(8): 766-767, 2009.

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Abstracts (continued) 74) Lange, E., Boerman, E.M., Segal, S.S., Jackson , W.F. Differences in expression and function of ryanodine receptors between arteries and arterioles in the mouse. FASEB J., 24:777.5, 2010. 75) Moore A.W., Jackson, W.F., Segal, S.S. Functional adrenoreceptor distribution in arteriolar networks of mouse gluteus maximus muscle. FASEB J. 24:976.5, 2010. 76) Westcott E.B., Jackson, W.F. Heterogeneous roles for FK506 binding proteins in the regulation of calcium signaling and myogenic tone in hamster cremaster feed arteries and arterioles. FASEB J, 25:817.4, 2011. 77) Behringer, E.J. Polo-Parada, L., Jackson, W.F. and Segal, S.S. Glycyrrhetinic acid derivatives block hyperpolarization concomitant with intercellular coupling along microvascular endothelial tubes. . FASEB J, 25:817.5, 2011. 78) Tykocki, N.R., Jackson, W.F. and Watts, S.W.. Endothelin-1 increases the frequency of smooth muscle calcium waves in vena cava but not aorta FASEB J 25:1026.2, 2011. 79) Jackson, W.F. Ion channels and microvascular function – an overview, J Vasc Res. 48(Suppl.1):41, 2011 (DOI:10.1159/000332604). 80) Westcott, E.B., Segal, S.S., Jackson, W.F. Aging differentially alters calcium signals and myogenic tone in murine cremaster muscle feed arteries and downstream arterioles. FASEB J 26:861.3, 2012. 81) Tykocki, N.R., Jackson, W.F. and Watts, S.W.. An imaging apparatus for simultaneous measurement of isometric contraction and Ca2+ fluorescence in large blood vessels of the rat. FASEB 26:870.31, 2012 82) Tykocki,N.R. Wu,, B., Jackson, W.F. and Watts, S.W.. Contraction of rat vena cava by endothelin-1 is dependent on phospholipase-Cβ, but independent of IP3 receptor activation FASEB J 26:1049.3, 2012. 83) Jackson, W.F. and Westscott, E.B. Arteriolar Smooth Muscle Calcium Waves Depend on Calcium Influx through Voltage-gated Calcium Channels. Hypertension 60:A488, 2012. 84) Bradley, V, Jackson W.F. Effects of aging on regulation of myogenic tone in small arteries of mice. Merial-NIH National Veterinary Scholars Symposium. 85) Hong, K., Nourian, Z., Reim, S. , Yu, X., Li, H., Yang, Y., Jackson, W.F. , Benbrook, A. , Kem, D.C., and Hill, M.A. Angiotensin II-independent Activation of AT1 Receptors in Skeletal Muscle Arterioles. FASEB J April 9, 2013 27:678.13 86) Hayoz, S., Segal, S.S. , and Jackson, W.F. Aging increases the amplitude of spontaneous transient outward currents in murine resistance artery smooth muscle cells. FASEB J April 9, 2013 27:679.4 87) Pires, P.W., Matin, M., Garver, H., Jackson, W.F., and Dorrance, A.M. Mechanisms of endothelial dysfunction in penetrating cerebral arterioles of DOCA-salt hypertensive rats. FASEB J April 9, 2013 27:678.7 88) Jackson WF, Westcott EB. BKCa channels are functionally coupled to L-Type Ca2+ channels but not IP3R-mediated Ca2+ waves in hamster cremaster arterioles. Proc 37th IUPS (2013) PCC353

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Abstracts (continued) 89) Ayala-Lopez N, Jackson WF, Wilson JN, Burnett R, Martini M, Frimodig K, Fink GD, Watts SW. The Presence of an Adrenergic System in Perivascular Adipose Tissue. Hypertension 62: A307, 2013. 90) Pires, PW. Jackson WF, Dorrance AM. Eplerenone Increases Dilation and the Diameter of Cerebral Penetrating Arterioles in Rats with Sustained Hypertension. Hypertension 62:A70, 2013. 91) Watts SW, Burnett R, Ayala-Lopez N, Mahon B, Dorrance AM, Jackson WF, Fink GD. Tyramine Reveals a Functional Adrenergic System in Perivascular Adipose Tissue. Hypertension 62: A407, 2013. 92) Ayala-Lopez N, Jackson WF, Wilson JN, and Watts SW. ASP+ reveals potential function of the serotonin transporter in perivascular adipose tissue (1170.8). FASEB J April 2014 28:1170.8 93) Hayoz S, Pettis J, Bradley V, Segal SS, and Jackson WF. Aging increases the amplitude of inward-rectifier K+ channel currents in murine resistance artery smooth muscle cells (677.8) FASEB J April 2014 28:677.8 94) Pires, PW, Jackson WF, Dorrance AM. Antihypertensive therapy reduces myogenic tone and increases the resting diameter of cerebral penetrating arterioles in hypertensive rats (1070.3). FASEB J April 2014 28:1070.3 96) Matin N, Jackson WF, Dorrance, AM. Bilateral Common Carotid Artery Stenosis in Normotensive Rats Impairs Short-Term Memory and Dilation in Penetrating Arterioles. Stroke. 2015;46:ATP416 97) Diaz-Otero JM, Jackson WF, and Dorrance AM. Aging Alters Vascular Stiffness in the Posterior Cerebral Artery in C57bl/6 Mice. Stroke. 2015;46:AWP395 98) Dorrance AM, P Pires, P, Jackson WF. Obesity Causes Endothelium Dysfunction in Rat Cerebral Parenchymal Arterioles. Stroke 46 (Suppl 1), AWP391-AWP391 99) Hayoz, S. Mullan, B, Washington, C, Segal, SS, and Jackson, WF. Advanced Age Increases the Amplitude of ATP-sensitive K+ Channel Currents in Murine Resistance Artery Smooth Muscle Cells. FASEB J April 2015 29:786.1 100) Matin N, Jackson WF, Fisher C, Dorrance, AM. Bilateral Common Carotid Artery Stenosis in Hypertensive Rats Impairs Dilation in Penetrating Arterioles and Posterior Communicating Arteries. Hypertension, in Press, P015, 2015.

Publications 1) Jackson, W.F. and P.O. Fromm. Effects of a detergent on flux of tritiated water into isolated perfused gills of rainbow trout. Comp. Biochem. Physiol. 58C: 167-171, 1977. 2) Jackson, W.F. and P.O. Fromm. Effect of acute acid stress on isolated perfused gills of rainbow trout. Comp. Biochem. Physiol. 67C: 141-145, 1980. 3) Jackson, W.F. and P.O. Fromm. Factors affecting the (3H)-water transfer capacity of isolated perfused trout gills. Am. J. Physiol. 240: R235-R245, 1981.

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Publications (continued) 4) Duling, B.R., I.H. Sarelius and W.F. Jackson. A comparison of microvascular estimates of capillary blood flow with direct measurements of total striated muscle flow. Int. J. Microcirc.: Clin. Exp. 1: 409-424, 1982. 5) Jackson, W.F. and B.R. Duling. Toxic effects of silver-silver chloride electrodes on vascular smooth muscle. Circ. Res. 53: 105- 108, 1983. 6) Jackson, W.F. and B.R. Duling. Oxygen sensitivity of hamster cheek pouch arterioles: In vitro and In situ studies. Circ. Res. 53: 515-525, 1983. 7) Jackson, W.F. Prostaglandins do not mediate arteriolar oxygen reactivity. Am. J. Physiol. 250: H1102-1108, 1986. 8) Jackson, W.F. Arteriolar oxygen reactivity: Where is the sensor? Am. J. Physiol. 253: H1120-H1126, 1987. 9) Jackson, W.F. Oscillations in active tension in hamster aortas: Role of the endothelium. Blood Vessels, 25: 144-156, 1988. 10) Jackson, W.F. Lipoxygenase inhibitors block O2 responses of hamster cheek pouch arterioles. Am. J. Physiol. 255: H711-H716, 1988. 11) Jackson, W.F. The endothelium-derived relaxing factor. J. Reconstruct. Microsurg. 5(3): 263-271, 1989. 12) Jackson, W.F. review of Pulmonary Endothelium in Health and Disease. Journal of Asthma, 26(4): 257-258, 1989. 13) Jackson, W.F. Arteriolar oxygen reactivity is inhibited by leukotriene antagonists. Am. J. Physiol. 257: H1565-H1572, 1989. 14) Jackson, W.F., Gauldin H.E., Tomita, H., Leatherbury, L. Neural crest ablation does not alter ventricular pressure or estimated cardiac output despite altered morphology. Annals N. Y. Acad. Sci. 558: 389-392, 1990. 15) Leatherbury, L., Braden, D.S., Tomita, H., Gauldin, H.E., Jackson, W.F. Hemodynamic changes: Wall stresses and pressure gradients in neural crest-ablated chick embryos. Annals N. Y. Acad. Sci. 558: 305-313, 1990. 16) Jackson, W.F., A. Mülsch and R. Busse. Rhythmic smooth muscle activity in hamster aortas is mediated by continuous release of NO from the endothelium. Am. J. Physiol. 260: H248-H253, 1991. 17) Hofman, W.F., W.F. Jackson, H. El-Kashef and I.C. Ehrhart. Modulation of vascular reactivity to serotonin in the dog lung. J. Appl. Physiol. 71(1): 217-222, 1991.

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Publications (continued) 18) Jackson, W.F. and P.M. Walsworth. Arteriolar vasomotion: a role for NO in the microcirculation? In: Resistance Arteries: Structure and Function, Eds. M.J. Mulvany, C. Aalkjaer, A.M. Heagerty, N.C.B. Nyborg, and S. Strandgaard, Elsevier Science Publishers, Excerpta Medica, International Congress Series 974, B.V., Amsterdam, pp.199-203, 1991. 19) Jackson, W.F. and R. Busse. Elevated guanosine 3':5'-Cyclic Monophosphate mediates the depression of nitrovasodilator reactivity in endothelium-intact blood vessels. Naunyn-Schmiedeberg's Archives of Pharmacology 344: 345-350, 1991. 20) Jackson, W.F. Nitric oxide does not mediate arteriolar oxygen reactivity. Microcirc. Endothel. Lymph. 7(4-6): 199-215, 1991. 21) Jackson, W.F., A. König, T. Dambacher, and R. Busse. Prostacyclin-induced vasodilation in the rabbit heart is mediated by ATP-sensitive potassium channels. Am. J. Physiol, 264, H238-H243, 1993. 22) Jackson, W.F. Role of Endothelium-Derived Nitric Oxide in Vasomotion. in Mechano Reception by the Vascular Wall, edited by G. Rubanyi, Futura Press, p. 173-196, 1993. 23) Jackson, W.F. Regional differences in the mechanism of action of oxygen on arterioles in the hamster. Am. J. Physiol. 265: H599-H603, 1993. 24) Jackson, W.F. Arteriolar tone is determined by the activity of ATP-sensitive potassium channels. Am. J. Physiol. 265: H1797-H1803, 1993. 25) Smith, M.P., S.J. Humphrey, W.F. Jackson. Selective in vivo antagonism of pinacidil-induced hypotension by the guanidine U37883A in anesthetized rats. Pharmacology 49: 363-375, 1994. 26) Jackson, W.F. Rp-Diastereomeric analogs of cAMP inhibit both cAMP-and cGMP-induced dilation of hamster small mesenteric arteries. Pharmacology 52: 226-234, 1996. 27) Jackson, W.F., D.R. Harder, R.J. Roman, J. Narayanan and J.H. Lombard. Cytochrome P-450 mediates arteriolar oxygen reactivity in hamster cremaster muscles. in Proceedings of the 6th World Congress for Microcirculation, edited by K. Messmer and W.M. Kübler, Monduzzi Editore, Bologna, p. 309-313, 1996. 28) Jackson, W.F. and N.J. Rusch. Voltage-activated and ATP-sensitive K+ channels regulate resting membrane potential in cremasteric arteriolar muscle cells. in Proceedings of the 6th World Congress for Microcirculation, edited by K. Messmer and W.M. Kübler, Monduzzi Editore, Bologna, p. 909-913, 1996. 29) Huebner, J.M., R.R. Eversole, W.F. Jackson, C.D. Mackenzie, S.R. Stapleton, and L.J. Beuving. Leukotriene C4 biosynthesis in isolated August rat peritoneal leukocytes. Mediators of Inflammation, 5: 443-447, 1996. 30) Jackson, W.F., J.M. Huebner, N.J. Rusch. Enzymatic isolation and characterization of single vascular smooth muscle cells from cremasteric arterioles. Microcirculation 3(3): 313-328, 1996 and 4(1): 35-50, 1997. 31) Jackson, W.F. and K.L. Blair. Characterization and function of Ca++-activated K+ channels in arteriolar muscle cells. Am. J. Physiol.274: H27-H34, 1998.

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Publications (continued) 32) Jackson, W.F. Potassium channels and regulation of the microcirculation. Microcirculation 5(2/3): 85-90, 1998. 33) Berger, M.G., C. Vandier, P. Bonnet, W.F. Jackson and N.J. Rusch. Intracellular acidosis differentially regulates KV channels in coronary and pulmonary vascular muscle. Am. J. Physiol. 275: H1351-H1359, 1998. 34) Welsh, D.G., W.F. Jackson and S.S. Segal. Oxygen induces electromechanical coupling in arteriolar smooth muscle cells: a role for L-type Ca++ channels. Am. J. Physiol. 274: H2018-H2024, 1998. 35) Jackson, W.F. Potassium channels in the control of basal vascular tone. Proceedings of 20th European Conference on Microcircualtion , Eds. P.H. Carpentier, E. Vicaut, and J.-L. Guilmot, Monduzzi Editore, Bologna,423-426, 1998. 36) Lombard, J.H.,M.P. Kunert, R.J. Roman, J.R. Falk, D.R. Harder and W.F Jackson. Cytochrome P-4504A ω- hydroxylase senses O2 in hamster muscles, but not in cheek pouch epithelium. Am. J. Physiol. 276: H503-H508, 1999. 37) Jackson, W.F. Hypoxia does not activate ATP-sensitive K+ channels in arteriolar muscle cells. Microcirculation 7: 137-145, 2000. 38) Jackson, W.F. Ion channels and vascular tone. Hypertension 35(part 2): 173-178, 2000. 39) Jackson, W.F. Potassium channels in skeletal muscle circulation. In Potassium channels in the cardiovascular biology , Eds. S.L. Archer and N.J. Rusch, Kluwer Academic/Plenum Publishers, New York, 2001, pp. 505-522. 40) Bukoski, R.D., S. Shearin, W.F. Jackson, and M.F. Pamarthi. Inhibition of Ca2+-induced relaxation by oxided tungsten wires and paratungstate. J Pharmacol Exp Ther, 299(1): 343-350, 2001. 41) Bukoski, R.D., S. Batkai, J. Járai, Y. Wang, W.F. Jackson and G. Kunos. The CB1 Receptor Antagonist SR141716A Inhibits Ca2+-Induced Relaxation in CB1 Receptor Deficient Mice. Hypertension 39(2): 251-257, 2002. 42) Jackson, W.F. Membrane potential and regulation of microvascular function. In Proceedings of the 7th World Congress for Microcirculation , Monduzzi Editore, Bologna, 2001. 43) Cohen, K.D. and W.F. Jackson. Hypoxia inhibits contraction but not calcium channel currents or changes in intracellular calcium in arteriolar muscle cells. Microcirculation 10: 133-141, 2003. 44) Burns, W. R. , K.D. Cohen and W.F. Jackson. K+-induced dilation of hamster cremasteric arterioles involves both the Na+/K+ ATPase and inward-rectifier K+ channels. Microcirculation, 11(3): 279-293, 2004. 45) Jackson, W.F. Ion channels and arteriolar tone, in Microvascular Research: Biology and Pathology, Volume 1, Chapter 34, edited by David Shepro, Academic Press, pages 221-228, 2005. 46) Jackson, W.F. Potassium Channels in the Peripheral Microcirculation. Microcirculation, 12(1): 113-127, 2005.

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Publications (continued) 47) Cohen, K.D. and W.F. Jackson. Membrane hyperpolarization is not required for sustained muscarinic receptor-mediated increases in Ca2+ in arteriolar endothelial cells. Microcirculation 12(2): 169-182, 2005. 48) Jackson, W.F. Potassium channels and proliferation of vascular smooth muscle cells. Circulation Research 97(12): 1211-2, 2005 (Editorial) 49) Brekke, J.F., Jackson, W.F. and Segal, S.S. Arteriolar smooth muscle Ca2+ dynamics during blood flow control in hamster cheek pouch. J Appl Physiol. 101(1):307-315, 2006. Epub 2006 Feb 2.. 50) Jantzi, M.C., Brett, S.E., Jackson, W.F., Corteling, R., Vigmond, E.J. and Welsh, D.G.. Inward Rectifying Potassium Channels Facilitate Cell-to-Cell Communication in Hamster Retractor Muscle Feed Arteries. Am J Physiol Heart Circ Physiol. 291(3):H1319-28, 2006. Epub 2006 Apr 14. 51) Jackson, W.F., Silent Inward Rectifier K+ Channels in Hypercholesterolemia. Circ Res. 98: 982-984, 2006. (Editorial) 52) Jackson W.F.. Invited Editorial Focus: Vascular smooth muscle store-operated Ca2+ channels: What a TRP! Am J Physiol Heart Circ Physiol. 291(6):H2592-4, 2006 Aug 18; [Epub ahead of print] 53) Xu, H, Jackson, W.F., , Fink, G.D. ,and Galligan, J.J. Activation of BK Channels by Tempol in Arterial Smooth Muscle Cells from Normotensive and DOCA-salt Hypertensive Rats. Hypertension 48(6):1080-1087, 2006. Epub 2006 Oct 23. 54) Hakim, C.H., Jackson, W.F. and Segal, S.S. Connexin Isoform Expression in Smooth Muscle Cells and Endothelial Cells of Hamster Cheek Pouch Arterioles and Retractor Feed Arteries. Microcirculation 15(6): 503 – 514, 2008. iFirst 03 June 2008. 55) Jackson, W.F., Boerman, E.M., Lange, E.J., Lundback, S.S., Cohen, K.D. Smooth muscle α1D-adrenoceptors mediate phenylephrine-induced vasoconstriction and increases in endothelial cell Ca2+ in hamster cremaster arterioles.. Br J Pharmacol. 155(4):514-24, 2008. Epub 2008 Jul 7.advance online publication, July 7, 2008; doi:10.1038/bjp.2008.276. 56) Jackson, W.F. Vanishing Act: PKC-dependent internalization of KATP channels. Hypertension, 52(3):470-2, 2008. Epub 2008 Jul 28 57) Jackson, W.F. KV1.3: A new therapeutic target to control vascular smooth muscle cell proliferation. Arterioscler Thromb Vasc Biol 30(6):1073-1074, 2010. 58) Moore AW, Jackson WF, Segal SS. Regional heterogeneity of {alpha}-adrenoreceptor subtypes in arteriolar networks of mouse skeletal muscle. J Physiol. 588 (Pt 21):4261-74, 2011. 59) Jackson, WF. Altered expression and function of ryanodine receptors and FKBP 12.6 after subarachnoid hemorrhage: more than meets the eye. J Cereb Blood Flow Metab. 31(1):1-2, 2011. 60) Jackson, WF. Quick Change Artist: EDHF in resistance arteries. Hypertension, 7(4):686-8. Epub 2011.

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Publications (continued) 61) Westcott EB, Jackson, WF. Heterogeneous function of ryanodine receptors, but not IP3 receptors in hamster cremaster muscle feed arteries and arterioles. Am J Physiol. Heart and Circulatory Physiol. 300(5):H1616-H630, 2011. 62) Socha, M.J., Hakim, C.H., Jackson, W.F., and Segal, S.S. Temperature effects on morphological integrity and Ca2+ signaling in freshly isolated mouse microvascular endothelial cell tubes. Am J Physiol Heart Circ Physiol 2011 Sep;301(3):H773-83, 2011. Epub 2011 Jun 24. PMID: 21705671 63) Jackson, W.F. Standing out in a crowd: Knockout of ApoE increases the potency of endothelium-dependent vasodilators in mesenteric arteries. Cardiovasc Res. 92(2): 183-4, 2011 Sep 21. [Epub ahead of print] PMID: 21937581. 64) Jackson, W.F. Microcirculation, Chapter 89, in Muscle: Fundamental biology and mechanisms of disease, Edited by Hill J and Olson, E.N., First Edition, Academic Press, London, 2012. ISBN: 9780123815101. 65) Westcott EB, Goodwin EL, Segal SS and Jackson, WF. Function and expression of ryanodine receptors and inositol 1,4,5 trisphosphate receptors in smooth muscle cells of murine feed arteries and arterioles. J. Physiol. 15;590(Pt 8):1849-69, 2012. 66) Tykocki, N.R., Jackson, W.F. and Watts, S.W.. Reverse-mode Na+/Ca2+ exchange is an important mediator of venous contraction. Pharmacological Research, 66(6): 544-554, 2012. 67) Tykocki, N.R., Thompson J.M., Jackson, W.F. and Watts, S.W Ryanodine receptors are uncoupled from contraction in rat vena cava, Cell Calcium, 53(2): 112-119, 2013. 68) Ayala-Lopez, N; Martini, M; Jackson, W.F.; Darios, E; Burnett, R.; Mahon, B; Fink, G.; Watts, S.Perivascular adipose tissue contains functional catecholamines. Pharmacol Res Perspect. 2014 Jun 1;2(3):e00041. PMID: 24904751 [PubMed] 69) Tykocki, N.R.,Wu, BinXi, Jackson, W.F. and Watts, S.W.. Divergent signalling mechanisms for venous versus arterial contraction as revealed by endothelin-1. J Vasc Surg. 2014 Apr 10. pii: S0741-5214(14)00358-9. doi: 10.1016/j.jvs.2014.03.010. [Epub ahead of print] PMID: 24726828 70) Hayoz, S., Bradley, V. Boerman, E.M., Nourian, Z., Segal, S.S. and Jackson W.F. Aging increases the size and spontaneous transient outward current amplitude of smooth muscle cells from murine superior epigastric arteries. Am J Physiol Heart Circ Physiol. 2014 Apr 4. [Epub ahead of print], PMID: 24705555. 71) Jackson WF. Arachidonate-induced dilation of retinal arterioles: more than meets the eye. Invest Ophthalmol Vis Sci. 2014 May 2;55(5). pii: 2903. doi: 10.1167/iovs.14-14510. PMID: 24793224 72) Stack A., Derksen F.J., William K.J., Robinson, N.E., and Jackson W.F. Lung Region and Racing Affect Mechanical Properties of Equine Pulmonary Microvasculature. J Appl Physiol. 2014 Aug 15;117(4):370-6. doi: 10.1152/japplphysiol.00314.2014. Epub 2014 Jun 12.PMID: 24925981 73) Robinson NE, Williams KJ, Stack A, Jackson WF, Derksen FJ. Exercise-induced pulmonary haemorrhage: A progressive disease affecting performance? Equine Vet J. 2015 Feb 24. doi: 10.1111/evj.12412. [Epub ahead of print] PMID: 25712624.

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Publications (continued) 74) Pires, PW, Jackson WF, Dorrance AM. Regulation of myogenic tone and structure of parenchymal arterioles by hypertension and the mineralocorticoid receptor. Am J Physiol Heart Circ Physiol. 309(1):H127-H136, 2015. PMID: 25910805; PMCID: PMC4491521. 75) Ayala-Lopez, N, Jackson WF, Burnett, R, Wilson, JN, Thompson JM, Watts SW. Organic Cation Transporter 3 Contributes to Norepinephrine Uptake into Perivascular Adipose Tissue. Am J Physiol Heart Circ Physiol. 309(11):H1904-14: 2015. doi: 10.1152/ajpheart.00308. Epub 2015 Oct 2. PMID: 26432838 76) Jackson, WF. Endothelial cell ion channel expression and function in arterioles and resistance arteries. In Vasuclar Ions Channels in Health and Disease, Edited by Levitan, I and Dopico, AM, Springer, in Press, 2015. 77) Diaz-Otero JM, Garver H, Fink GD, Jackson WF, Dorrance AM. Aging is associated with changes to the biomechanical properties of the posterior cerebral artery and parenchymal arterioles. Am J Physiol Heart Circ Physiol. 2015 Dec 4:ajpheart.00562.2015. doi: 10.1152/ajpheart.0056, 2015. PMID: 26637558. 78) Stack A, Derksen FJ, Williams KJ, Robinson NE Emeritus Prof, Jackson WF. Regional heterogeneity in the reactivity of equine small pulmonary blood vessels. J Appl Physiol (1985). 2016 Jan 14:jap.00975.2015. doi: 10.1152/japplphysiol.00975.2015. [Epub ahead of print]. PMID: 26769957