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© 2011 Exempla Healthcare Thoracentesis Aaron J. Calderon, MD, FACP, SFHM Associate Program Director, Internal Medicine Residency, Exempla Saint Joseph Hospital Founder, GME Simulation/Procedural Skills Lab, Exempla Saint Joseph Hospital Associate Clinical Professor of Medicine, University of Colorado Denver [email protected] © 2011 Exempla Healthcare Disclosures I have no financial or other disclosures related to this activity 2 © 2011 Exempla Healthcare

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© 2011 Exempla Healthcare

Thoracentesis

Aaron J. Calderon, MD, FACP, SFHM Associate Program Director, Internal Medicine Residency, Exempla Saint Joseph Hospital

Founder, GME Simulation/Procedural Skills Lab, Exempla Saint Joseph Hospital Associate Clinical Professor of Medicine, University of Colorado Denver

[email protected]

© 2011 Exempla Healthcare

Disclosures

•  I have no financial or other disclosures related to this activity

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© 2011 Exempla Healthcare

© 2011 Exempla Healthcare

Indications

•  Unexplained •  Parapneumonic •  Therapeutic

© 2011 Exempla Healthcare

Relative Contraindications

•  PT and/or PTT ≥ 2x normal •  Platelet count ≤ 25,000 – 50,000 •  Creatinine ≥ 6.0 •  Unstable patient •  Infection over insertion site •  Mechanical Ventilation •  If doesn’t meet Light’s criteria for landmark

© 2011 Exempla Healthcare

© 2011 Exempla Healthcare

© 2011 Exempla Healthcare

Procedure

•  Time-out •  1-2 interspaces below where dull •  Above the rib •  Do not go below rib 9 •  Use Chlorhexidine •  Vacuum vs. Push & Pull •  Exhale/Valsalva during removal

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Upright position Sit upright leaning forward

Supine position Head of bed elevated 30 degrees

Patient Positions

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© 2011 Exempla Healthcare

Ultrasound Use

•  No blinded RCTs •  Associated with lower complications •  Only “real-time” ultrasound •  Consider for:

•  Vented patients •  Severe COPD or malignant effusions •  Coagulopathy •  Tiny or loculated •  All patients

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2010 British Thoracic Society Guidelines

•  Thoracic ultrasound guidance is strongly recommended for all pleural procedures for pleural fluid. (B)

•  The marking of a site using thoracic ultrasound for subsequent remote aspiration or chest drain insertion is not recommended except for large pleural effusions. (C)

© 2011 Exempla Healthcare

Residency Review Committee for Pulmonary Medicine

•  RRC now mandates as of 7/1/2012 •  All pulmonary fellows are required to be

trained in the use of ultrasound to perform thoracentesis

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Thoracentesis Procedure

•  Transducer is placed either sagittal or transverse on the patient’s back

•  Locate and mark deepest fluid pocket

•  Prep and drape patient and transducer per standard sterile technique

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Ultrasound Anatomy

The pleural space lies between the visceral and parietal pleura

liver

diaphragm

pleural fluid

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Thoracentesis Procedure

lung liver

diaphragm

pleural fluid

© 2011 Exempla Healthcare

Thoracentesis Procedure

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Complications

•  Pneumothorax •  Re-expansion pulmonary edema •  Bleeding •  Infection •  Vagal reaction

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 Initial chest x ray.

McRoberts R et al. Emerg Med J 2005;22:597-598

Copyright © BMJ Publishing Group Ltd and the College of Emergency Medicine. All rights reserved.

© 2011 Exempla Healthcare

© 2011 Exempla Healthcare

Complication Rate

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Tension Pneumothorax

•  Chest pain, hypotension, tachycardia •  Emergent needle decompression •  Use no smaller than 3.25 inch 14 gauge

needle •  Smaller needle size associated with high

failure rate •  2nd intercostal space;mid-clavicular line

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© 2011 Exempla Healthcare

Follow-up CXR

•  Debatable •  No good evidence to support if procedure

went smoothly and low-risk patient •  I wouldn’t recommend routine CXR

© 2011 Exempla Healthcare

2010 British Thoracic Society Guidelines

•  Follow Up CXR

- A chest x-ray after a simple pleural aspiration is not required unless air is withdrawn, the procedure is difficult, multiple attempts are required or the patient becomes symptomatic. (C)

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CONCLUSIONS: “BEDSIDE ULTRASOUND PERFORMED BY CLINICIANS HAD A HIGHER SENSITIVITY AND SIMILAR SPECIFICITY COMPARED TO CXR FOR THE DIAGNOSIS OF PNEUMOTHORAX, BUT THE ACCURACY OF ULTRASOUND DEPENDED ON THE SKILL OF THE OPERATORS.”

CHEST 2011; 140(4):859-866

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© 2011 Exempla Healthcare

Reexpansion Pulmonary Edema

•  Rare complication •  Dyspnea, tachypnea, cough, fever, tachycardia •  Unilateral pulmonary edema in lung that rapidly

reexpands •  Typically occurs in lung that has been collapsed for ≥ 3

days •  Usually occurs in first few hours of reexpansion; almost all

by 24hrs •  May last 2-5 days

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© 2011 Exempla Healthcare

Reexpansion Pulmonary Edema Treatment • Supportive care(O2, pain meds) • Diuretics not recommended Prevention • Limit fluid removal to 1-1.5 liter • If measuring pleural pressure keep above -20 cm H20 • Cough or chest tightness correlate

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© 2011 Exempla Healthcare

© 2011 Exempla Healthcare

What to Order with the Fluid?

•  Cell count, gram stain, and culture •  LDH and protein •  pH •  Cytology •  Glucose •  Serum LDH and protein

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© 2011 Exempla Healthcare

Light’s Criteria Exudate vs Transudate

Only need one of the following to meet criteria for an exudative pleural effusion: •  Pleural LDH/Serum LDH > .6 •  Pleural LDH > 2/3 ULN of serum LDH •  Pleural protein/Serum protein >.5

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© 2011 Exempla Healthcare

Light’s Criteria CHF on Diuretics

•  Transudates misclassified as exudates 20-25% of the time

•  Options to better classify these patients: – Serum albumin/pleural albumin of >1.2 g/dl – Serum protein/pleural protein >3.1 g/dl – Pleural NT-pro-BNP levels >1300 (best test if

available) Light RW. Use of pleural fluid N-terminal-pro-brain natriuretic peptide and brain

natriuretic peptide in diagnosing pleural effusion due to congestive heart failure. Chest. Sep 2009;136(3):656-8.

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Exudative vs Transudative Based on Pleural Fluid Alone

•  Correlates fairly well with Light’s criteria •  The presence of any of the following indicates a exudative

effusion: - Pleural LDH >.45 the ULN of serum LDH - Pleural Cholesterol > 45 mg/dl - Pleural Protein > 2.9 g/dl

Heffner JE, Brown LK, Barbieri CA. Diagnostic value of tests that discriminate between exudative and transudative pleural effusions. Primary Study Investigators. Chest. Apr 1997;111(4):970-80

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