this article and any supplementary material should be cited as follows: nitz jc, perrier j, cook p....
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This article and any supplementary material should be cited as follows: Nitz JC, Perrier J, Cook P. In-vivo trial results of a novel ultrasonic cough stimulator. J Rehabil Res Dev. 2012;49(9):1421–30. http://dx.doi.org/10.1682/JRRD.2011.07.0121
Slideshow ProjectDOI:10.1682/JRRD.2011.07.0121JSP
In-vivo trial results of a novel ultrasonic cough stimulator
Jennifer C. Nitz, PhD, MPhty, BPhty; John Perrier, BPhty;
Peter Cook, MBBS, FANZCA, FCICM
This article and any supplementary material should be cited as follows: Nitz JC, Perrier J, Cook P. In-vivo trial results of a novel ultrasonic cough stimulator. J Rehabil Res Dev. 2012;49(9):1421–30. http://dx.doi.org/10.1682/JRRD.2011.07.0121
Slideshow ProjectDOI:10.1682/JRRD.2011.07.0121JSP
• Aim– Establish:• Whether ultrasound (US) stimulation can safely stimulate
cough.• Most efficient US frequency.• Whether single- or dual-sided stimulation is more
effective.
• Relevance– Ability to cough voluntarily is absent or diminished
in many clinical situations, which may predispose patients to or prolong respiratory diseases.
This article and any supplementary material should be cited as follows: Nitz JC, Perrier J, Cook P. In-vivo trial results of a novel ultrasonic cough stimulator. J Rehabil Res Dev. 2012;49(9):1421–30. http://dx.doi.org/10.1682/JRRD.2011.07.0121
Slideshow ProjectDOI:10.1682/JRRD.2011.07.0121JSP
Method• Applied stimulation with
CoughStim device to 15 nondisabled and 7 unable-to-cough volunteers:– Unilaterally: 8 frequencies
and 2 power levels.– Bilaterally: 2 frequencies
and 3 power levels.
This article and any supplementary material should be cited as follows: Nitz JC, Perrier J, Cook P. In-vivo trial results of a novel ultrasonic cough stimulator. J Rehabil Res Dev. 2012;49(9):1421–30. http://dx.doi.org/10.1682/JRRD.2011.07.0121
Slideshow ProjectDOI:10.1682/JRRD.2011.07.0121JSP
Results
• Nondisabled subjects– Cough stimulated:• 80% at 0.58 MHz and 9 W unilaterally.
• 75% at 0.58 MHz and 6 W bilaterally
• Unable-to-cough subjects– Cough stimulated:• 71% at 0.54 MHz and 6 W bilaterally.
This article and any supplementary material should be cited as follows: Nitz JC, Perrier J, Cook P. In-vivo trial results of a novel ultrasonic cough stimulator. J Rehabil Res Dev. 2012;49(9):1421–30. http://dx.doi.org/10.1682/JRRD.2011.07.0121
Slideshow ProjectDOI:10.1682/JRRD.2011.07.0121JSP
Conclusion
• CoughStim device:– Regularly and safely produced moderately strong
cough response in subjects with or without ability to cough.
– Produced this effect without causing undue discomfort.