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The Undetectables Project! North American Housing and HIV/AIDS Research Summit Washington D.C. • September 15, 2015 • Toorjo Ghose, University of Pennsylvania • Stephen Nolde, Housing Works, Inc. www.housingworks.org

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The Undetectables Project!North American Housing and HIV/AIDS

Research SummitWashington D.C. • September 15, 2015

• Toorjo Ghose, University of Pennsylvania• Stephen Nolde, Housing Works, Inc.

www.housingworks.org

Presenter
Presentation Notes
We set out to determine the efficacy, feasibility and cost-effectiveness of financial incentives as a part of a comprehensive community-based care program designed to support ARV adherence and population-level viral suppression amongst a cohort of homeless and formerly homeless persons with HIV who receive integrated health and social services at a NYC CBO. An Undetectables superhero marketing campaign was launched to promote viral suppression as a core principle of the HW community, counter stigma and encourage open discussion of viral loads and peer-based ARV adherence support. The program also includes agency-wide staff training on viral suppression and regular case management staff trainings and support on the use of motivational interviewing to promote medication adherence.

Who’s participating?

• Housing Works is a NYC community-based organization providing integrated care for homeless and formerly homeless people with HIV/AIDS

– Primary health care– Behavioral health services– Housing and assistance with other basic subsistence needs– Case management and care coordination

• Approximately 1,500 active HIV+ clients– 84% black or Hispanic– 33% identify as gay, lesbian, bisexual, trans or gender non-conforming– > 50% histories of incarceration – > 50% co-infection with HepC– 100% living at or below poverty line– 90% extended histories of mental illness and/or chemical dependence

Presenter
Presentation Notes
Housing Works is a healing community of people living with and affected by HIV/AIDS. Our mission is to end the dual crises of homelessness and AIDS through relentless advocacy, the provision of lifesaving services, and entrepreneurial businesses that sustain our efforts. Housing Works’ community includes PWH who have access to insurance coverage for clinically appropriate care but who face multiple barriers to consistent care and ARV adherence.

What is the Undetectables Project?

• Launched in March 2014 using a community support model

• 24-month grant-funded pilot to assist HIV+ participants to achieve and maintain undetectable viral load (≤50 copies/ml)

• Eligibility: clients receiving integrated care (primary health care and case management/care coordination) at Housing Works

• Enrollment: 610 active participants as of the end of August 2015 with an overall 80% retention rate at 18 months

• Goal: at least 80% viral suppression in the HW community

• A core component of Housing Works’ commitment to the New York plan to end the state’s AIDS epidemic by 2020

Presenter
Presentation Notes
Enrollment in the pilot is open to all HIV-positive clients receiving integrated care at Housing Works Eligible clients receive primary care at HW and are active clients in at least one additional HW program that provides case management or care coordination NYS is developing a plan to AIDS as an epidemic by 2020 by dramatically reducing HIV-related mortality and morbidity and lowering the rate of ongoing transmissions to a level below .5% annually 25 Years ago people said that homeless persons with AIDS could not be housed. Housing Works, using a low-threshold, harm reduction approach, employed housing, supportive services, primary care and behavioral health – and have proved the doubters wrong. Now is the time to prove we can end AIDS as an epidemic – we are going to do it, and we are going to start with our community!

What’s in the toolkit?

Stepped approach to ARV adherence

Individual-level ARV adherence planning and support– case conferences among client, health providers & case manager– motivational interviewing & assistance to meet subsistence needs – Behavioral health assessment/referral

$100 gift card incentive for quarterly lab result showing undetectable viral load (≤50 copies/ml), up to 4 per year

Cognitive behavioral therapy (CBT) adherence support groups Adherence devices such as pill-boxing and text or other daily

medication reminders Directly observed ARV therapy (DOT) – formal and informal

Presenter
Presentation Notes
Cost-effective approach moving from least intensive/expensive (care coordination & gift card incentive) to most intensive/resource rich (DOT). Tools not mutually exclusive; no order required; but stepped protocol assumes incentive will work for 70-80% of participants; CBT groups for 80% of remaining; adherence devices for 80% of remaining; DOT for small number still remaining. All have a behavioral health visit with a psychiatric nurse practitioner to evaluate behavioral health barriers to ARV adherence and make appropriate referrals to mental health services, harm reduction programs or other substance use treatment services

Evaluation design

• Community based participatory approach in collaboration with academic partners at the University of Pennsylvania

• Study examining efficiency, feasibility & cost-effectiveness• Using each participant as his/her control, assess viral load and

cumulative viral exposure pre and post enrollment• Qualitative interviews and focus groups with participants and staff

to examine attitudes regarding program efficacy• Standard methods of cost analysis to evaluate cost-utility as a

function of incremental program costs and medical costs saved through averted downstream infections

Presenter
Presentation Notes
Upenn PI Dr. Toorjo Ghose worked with Housing Works to model the Undetectables project and evaluation plan on a successful community support-driven HIV prevention and care intervention he developed in collaboration with a sex workers union in India.

Durable viral suppression at9 months

Presenter
Presentation Notes
This analysis includes the 75% of enrolled clients (363 of 486) for whom we have VL lab results for at least 2 time points prior to project enrollment.

How is it going?

• High-level agency-wide buy-in and oversight– Regular meetings of executive team and senior staff – 2 Year enrollment goal met early– Successes and challenges

• Program-level evaluation and quality assurance & improvement– Regular meetings of program directors– Ongoing monitoring and evaluation of process and outcome indicators– Evolving agency and program-level strategies – Next steps

• Tracking and monitoring– Tracking systems and tools– Staff survey– Client interviews and focus groups

Presenter
Presentation Notes
One example of an evolving strategy is transforming the CBT adherence groups into an opportunity/program for participants to become peer group facilitators

Results at 18 months:viral load suppression

• Pre-enrollment: among 441 clients eligible for enrollment at project launch:

– 54% virally suppressed using ≤50 copies/mil as the measure– 37% detectable – 9% unknown (refused testing or inconclusive result)

• Current for all 610 clients enrolled at August 31, 2015:– 83% virally suppressed using ≤50 copies/mil as the measure– 15% detectable – 2% unknown (refused testing or inconclusive result)

• Current for 554 clients enrolled ≥ 3 months at August 31, 2015:– 85% virally suppressed using ≤50 copies/mil as the measure– 14% detectable – 1% unknown (refused testing or inconclusive result)

Presenter
Presentation Notes
The number of eligible clients has grown since the program launched as additional clients enroll in the integrated care model of primary care plus one additional life-saving service (housing, behavioral health care, care coordination, etc). Clinical Director provides a monthly report to case management team regarding Residential Viral Load results. Case Managers, in turn, develop a comprehensive plan to assist residents who are not virally suppressed. Clinical Director provides clinical supervision to address client barriers and to develop a strength-based approach to assist residents with multiple barriers/needs. Blood drawn for viral load assays by Housing Works primary care clinics.

Housing Specific VLS Interventions

• 166 units: 110 in 5 community residences; 56 scatter site• Weekly face-to-face meetings with all housing residents

– Daily case manager contact with clients in community residences– Option of informal DOT or pill boxing through case managers

• Clinical Director & Case Managers check-in monthly on VLS and use strength-based plans for residents with multiple barriers/needs

• Monthly apartment visits by case management team to speak directly with residents in their homes about health

• Share viral load results as well as challenges and success stories monthly within Housing Department and with HW leadership

• Housing clients in the Undetectables at 85% overall• ≥ 95% VLS last 6 months for Undetectables participants living in

transitional residence for recently incarcerated women; ≥80% for Undetectables participants in transgender scatter site program

Presenter
Presentation Notes
Since January 2015, the Housing Department’s Viral Suppression Rate (<50), has been above the 80% suppression rate. Utilizing the Undetectables Program as an impetus, Housing has reinforced this incentive-based program with home-based clinical interventions.

Viral Load Suppression: All Housing Clients

65 66 66

73 74 73

77

84 83 84

88 8987

85 84 85

70 70

7876

79

75

84

89

84 8588

8587

85 85 85

60 61

54

6966

70 69

77

8183

88

94

87

83 82 8380 80 80 80 80 80 80 80 80 80 80 80 80 80 80 80

% VLS Total (All of Housing) % VLS @ Housing Works Primary Care

% VLS @ External Primary Care Targeted Goal

Why become anUndetectable?

• Becoming an Undetectable is becoming a Hero!

• Becoming an Undetectable improves your health, well being, and your life expectancy!

• Becoming an Undetectable can reduce the likelihood of transmitting HIV to sexual partners!

• Becoming an Undetectable helps to end the HIV epidemic!

Acknowledgements

• Funded by the Robin Hood Foundation • http://www.robinhood.org• Housing Works co-authors:

– Matthew Bernardo– Michael Clarke – Andrew Greene– Charles King – Alison Kliegman– Vaty Poitevien– Ken Robinson– Ginny Shubert

• University of Pennsylvania co-authors:– Sambuddha Chaudhuri

Questions? Contact Ginny Shubert at [email protected]