the treatment of aneurysm by the subcutaneous injection of gelatin

1
796 which Miss Anderson was the first to call attention in 1894, B the tongue is now generally replaced by an artificial damper. We hope to return to the subject in an early number. A WARNING. WE are requested to bring the following facts before our readers. A woman giving the name of Mrs. M. K. Harvey is going about the country asking medical men and others who are not medical men for assistance. She gives as references the names of prominent members of the profession and in one instance at least as proof of her respectability gave out that she was just about to be married to a well- known physician-a statement which is absolutely false; moreover, the physician in question knows nothing of the woman. The description of the woman is as follows. She is short, about five feet in height, very broad and fat. She has muddy blue eyes with pin-point pupils. (She takes morphia.) She has prominent teeth, some false, has short features and dark hair turning grey at the temples, cut as a fringe in front. Her manners and speech are ladylike. THE NEW HOSPITAL AT BISHOP AUCKLAND. ON Sept. 8th Lord Rosebery opened a new cottage hospital at Bishop Auckland. The hospital was originated by Lady Eden in commemoration of Her Majesty’s Diamond Jubilee and has cost about 2000. Lord Rosebery, who spoke in his usual happy vein, referred to the fact that some people were anxious for the State to provide everything. But the State, as he pointed out, is after all only an aggregation of individuals whose independence and self-reliance went to make up all that is of value in the State. Strike at the independence of individuals and the State vanishes. "I welcome the fact," continued his lordship, "that the miners of this district are going to show an honourable in- dependence and an honourable self-reliance by rating them- selves to maintain this hospital." We can join in cordially congratulating the Durham miners upon their decision and all the more so in that we have at times felt it to be our duty to say hard things as to the way in which they looked on the payment of their medical officers. But in the matter of their hospital they have done nobly and for their action they deserve commendation. ___ THE TREATMENT OF ANEURYSM BY THE SUB- CUTANEOUS INJECTION OF GELATIN. THE treatment of aneurysm by the subcutaneous injection of gelatin recently introduced by M. Lancereaux has yielded remarkable results. In THE LANCET of Oct. 22nd, 1898, p. 1092, the procedure was described; 250 cubic centimetres of a solution of 2 grammes of gelatin in 100 grammes of saline solution are injected under the skin of the thigh. The in- jection is renewed at varying intervals from every two to 15 days. As a rule, 10, 15, or 20 injections produce complete cure. They act by increasing the coagulability of the blood. In the Journal de Médecine Interne of July 1st, 1899, Professor Stoicesco of Bucharest has reported six cases of aneurysm of the aorta and innominate artery treated by this method. The results are striking and fully confirm M. Lancereaux’s claims. A woman, aged 36 years, had aneurysm of the ascending aorta. There was considerable dyspnoea and the patient could not lie on her back. The face was oedematous and cyanosed and the veins of the neck were dilated. A pulsatile hemi- spherical tumour occupied the right, first, and second inter- costal spaces. On March 3rd 83 cubic centimetres of a 1 per cent. solution of gelatin were injected subcutaneously; on the 6th 105 cubic centimetres ; on the 9th 120 cubic centimetres ; on the 16th 120 cubic centimetres; and on the 25th 120 cubic centimetres. The tumour became harder and the expansile movements less pronounced, and the dyspnoen and difficulty of the circulation were much diminished. The patient left hospital and was lost sight of. In another case a woman, aged 55 years, had aneurysm of the innominate artery. In the right subclavicular region was a pulsatile tumour of the size of an orange. On July 15th 80 cubic centimetres of a 1 per cent. solution of gelatin were injected subcutaneously. On the 17th the tumour appeared smaller and firmer and the pulsations were less super- ficial. On the 25th 100 cubic centimetres were injected. On the 27th the tumour had diminished to the size of a pigeon’s egg. On April 5th 100 cubic centimetres of a 2 per cent. solution were injected which was followed by intense pain at the seat of injection. The tumour progressively decreased to the size of a filbert and the pulsations were no longer superficial. On August 8th the patient was discharged completely recovered. On March 8th, 1899, she was seen again; the good result was maintained and the tumour was of the same volume as at the time of dis- charge. In a case of aneurysm of the ascending part of the arch of the aorta compressing the vena cava and also causing intense dyspnoea the patient died two hours after a single injection. The arch of the aorta was found to be dilated in its whole extent and presented a large sac in its right half which contained some organised clots and one recent clot. In the left carotid artery about 6 centimetres above its orifice was an adherent clot 1½ centimetre in length. The injection was found to have been completely absorbed. In the other cases the results were very satisfactory and in one (aneurysm of the innominate artery) the patient was long enough under observation to enable the permanence of the result to be proved. ------ MEDICAL ORGANISATION. As will be seen by a letter published in another column the Manchester Medical Guild is endeavouring to organise a conference of delegates from all societies or associations of general practitioners in the country. The objects of the conference may be shortly stated as follows :- 1. To promote greater cohesion and better organisation amongst the general practitioners of the country and generally to develope an esprit de corps. 2. To afford general practitioners from all parts of the country an opportunity of meeting together and discussing all matters affecting their welfare and in this way of bringing their views to a focus. 3. By giving publicity to their views on questions affecting them to influence public opinion in their favour and thus to uphold and improve the status of the profession. 4. To provide some machinery by which the advantages of an annual conference may be secured to the profession. It may be seen from the above that it is proposed that the conference should devote itself purely to medico-ethical and medico-political questions and leave scientific matters entirely alone. There are many questions-amongst which may be enumerated the following, viz., contract practice, the con- stitution of the General Medical Council and its attitude towards the general practitioner, the proposed new Medical Act, the proposed legislation for midwives, hospital abuse, district nursing, and the proposed conciliation board-about which it is very desirable that the voice of the profession should make itself heard in a manner at once unmistakeable and unanimous, and such a result may very well be obtained if the proposed conference should be successful and repre- sentative. It may be said that the profession is resorting to the methods of those who devote themselves to trade. This may be so, but it must be remembered that the majority of medical men depend upon their profession for their daily bread and there is no profession which is so exposed to the competition of quacks and heretics. Nay more, the medical profession’s whole raison d’être is to get rid of, so far as may be, the very set of conditions which make

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Page 1: THE TREATMENT OF ANEURYSM BY THE SUBCUTANEOUS INJECTION OF GELATIN

796

which Miss Anderson was the first to call attention in 1894,

Bthe tongue is now generally replaced by an artificial damper.We hope to return to the subject in an early number.

A WARNING.

WE are requested to bring the following facts before ourreaders. A woman giving the name of Mrs. M. K. Harveyis going about the country asking medical men and otherswho are not medical men for assistance. She gives asreferences the names of prominent members of the professionand in one instance at least as proof of her respectabilitygave out that she was just about to be married to a well-known physician-a statement which is absolutely false;moreover, the physician in question knows nothing of thewoman. The description of the woman is as follows. She

is short, about five feet in height, very broad and fat. She

has muddy blue eyes with pin-point pupils. (She takesmorphia.) She has prominent teeth, some false, has shortfeatures and dark hair turning grey at the temples, cut as afringe in front. Her manners and speech are ladylike.

THE NEW HOSPITAL AT BISHOP AUCKLAND.

ON Sept. 8th Lord Rosebery opened a new cottagehospital at Bishop Auckland. The hospital was originatedby Lady Eden in commemoration of Her Majesty’sDiamond Jubilee and has cost about 2000. Lord

Rosebery, who spoke in his usual happy vein, referredto the fact that some people were anxious for the Stateto provide everything. But the State, as he pointedout, is after all only an aggregation of individualswhose independence and self-reliance went to make

up all that is of value in the State. Strike at

the independence of individuals and the State vanishes."I welcome the fact," continued his lordship, "that theminers of this district are going to show an honourable in-dependence and an honourable self-reliance by rating them-selves to maintain this hospital." We can join in cordiallycongratulating the Durham miners upon their decision andall the more so in that we have at times felt it to be our dutyto say hard things as to the way in which they looked on thepayment of their medical officers. But in the matter of their

hospital they have done nobly and for their action theydeserve commendation.

___

THE TREATMENT OF ANEURYSM BY THE SUB-CUTANEOUS INJECTION OF GELATIN.

THE treatment of aneurysm by the subcutaneous injectionof gelatin recently introduced by M. Lancereaux has yieldedremarkable results. In THE LANCET of Oct. 22nd, 1898,p. 1092, the procedure was described; 250 cubic centimetres ofa solution of 2 grammes of gelatin in 100 grammes of salinesolution are injected under the skin of the thigh. The in-

jection is renewed at varying intervals from every two to 15days. As a rule, 10, 15, or 20 injections produce completecure. They act by increasing the coagulability of the blood.In the Journal de Médecine Interne of July 1st, 1899, ProfessorStoicesco of Bucharest has reported six cases of aneurysm ofthe aorta and innominate artery treated by this method. Theresults are striking and fully confirm M. Lancereaux’s claims.A woman, aged 36 years, had aneurysm of the ascending aorta.There was considerable dyspnoea and the patient could notlie on her back. The face was oedematous and cyanosedand the veins of the neck were dilated. A pulsatile hemi-spherical tumour occupied the right, first, and second inter-costal spaces. On March 3rd 83 cubic centimetres of a

1 per cent. solution of gelatin were injected subcutaneously;on the 6th 105 cubic centimetres ; on the 9th 120 cubic

centimetres ; on the 16th 120 cubic centimetres; and on the25th 120 cubic centimetres. The tumour became harder and

the expansile movements less pronounced, and the dyspnoenand difficulty of the circulation were much diminished. The

patient left hospital and was lost sight of. In another casea woman, aged 55 years, had aneurysm of the innominateartery. In the right subclavicular region was a pulsatiletumour of the size of an orange. On July 15th 80 cubiccentimetres of a 1 per cent. solution of gelatin were

injected subcutaneously. On the 17th the tumour appearedsmaller and firmer and the pulsations were less super-ficial. On the 25th 100 cubic centimetres were injected.On the 27th the tumour had diminished to the size ofa pigeon’s egg. On April 5th 100 cubic centimetres of a2 per cent. solution were injected which was followed

by intense pain at the seat of injection. The tumour

progressively decreased to the size of a filbert and the

pulsations were no longer superficial. On August 8th thepatient was discharged completely recovered. On March 8th,1899, she was seen again; the good result was maintained andthe tumour was of the same volume as at the time of dis-

charge. In a case of aneurysm of the ascending part of thearch of the aorta compressing the vena cava and also causingintense dyspnoea the patient died two hours after a singleinjection. The arch of the aorta was found to be dilated inits whole extent and presented a large sac in its right halfwhich contained some organised clots and one recent clot.In the left carotid artery about 6 centimetres above its orificewas an adherent clot 1½ centimetre in length. The injectionwas found to have been completely absorbed. In the othercases the results were very satisfactory and in one (aneurysmof the innominate artery) the patient was long enough underobservation to enable the permanence of the result to be

proved. ------

MEDICAL ORGANISATION.

As will be seen by a letter published in another columnthe Manchester Medical Guild is endeavouring to organise aconference of delegates from all societies or associations ofgeneral practitioners in the country. The objects of theconference may be shortly stated as follows :-

1. To promote greater cohesion and better organisationamongst the general practitioners of the country andgenerally to develope an esprit de corps. 2. To affordgeneral practitioners from all parts of the country an

opportunity of meeting together and discussing all mattersaffecting their welfare and in this way of bringing theirviews to a focus. 3. By giving publicity to their views onquestions affecting them to influence public opinion in theirfavour and thus to uphold and improve the status of theprofession. 4. To provide some machinery by which theadvantages of an annual conference may be secured to theprofession.It may be seen from the above that it is proposed that theconference should devote itself purely to medico-ethical andmedico-political questions and leave scientific matters entirelyalone. There are many questions-amongst which may beenumerated the following, viz., contract practice, the con-stitution of the General Medical Council and its attitudetowards the general practitioner, the proposed new MedicalAct, the proposed legislation for midwives, hospital abuse,district nursing, and the proposed conciliation board-aboutwhich it is very desirable that the voice of the professionshould make itself heard in a manner at once unmistakeableand unanimous, and such a result may very well be obtainedif the proposed conference should be successful and repre-sentative. It may be said that the profession is resortingto the methods of those who devote themselves to

trade. This may be so, but it must be remembered thatthe majority of medical men depend upon their professionfor their daily bread and there is no profession which is soexposed to the competition of quacks and heretics. Naymore, the medical profession’s whole raison d’être is to get ridof, so far as may be, the very set of conditions which make