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Dr Richard Stanwick, CMHO, VIHA July 24 th , 2012 The Risks of Tanning Challenging the Myths, Confirming the Attraction and Advocating Effectively

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Page 1: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Dr Richard Stanwick, CMHO, VIHA

July 24th, 2012

The Risks of Tanning –

Challenging the Myths,

Confirming the Attraction and

Advocating Effectively

Page 2: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Introduction

I have no affiliation with any commercial organization that

may have a direct or indirect connection to the content of my

presentation.

In particular, this declaration applies to:

Chemical sunscreen manufacturers

The cosmetic dermatology industry

The commercial tanning industry

I am not participating in any clinical trials sponsored by a

commercial organization that may have a direct or indirect

connection to the content of my presentation.

Page 3: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Objectives

To understand photobiology of tanning from UV

sources

To understand why skin cancer is increased

from tanning bed exposure

To review recent evidence implicating tanning

bed exposure in skin cancer development

To review various healthy public policy options

and examine effective advocacy strategies.

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Page 5: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

20,000 Years Ago…

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Adaptation

Man has seen only minor changes in

200,000 years, and virtually none in 20,000

We have not adapted well to a new lifestyles

in 200 years and the challenges have

accelerated in the last 50 years.

Page 7: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

What is

a tan?

Page 8: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

UVA(320-400nm)

UVB(290-320nm)

EMR Spectrum

Ultraviolet Radiation

Page 9: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

UV Radiation at Earth’s surface

5% UVB

290-320nm 95% UVA

320-400nm

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Fitzpatrick Skin Types

Page 11: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

UVB UVA

Sunburn Tanning

Langerhans cell

depletion

Cellular apoptosis

or cell cycle arrest

Stress proteins,

cytokine production

ACUTE EFFECTS

Page 12: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Physiologic Changes with UVA & UVB • UVA

• Immediate pigment darkening and redistribution of melanosomes

• Provides no protection against further UV damage

• UVB

• Increased melanocytes, increased melanin synthesis, more pronounced epidermal thickening and hyperkeratosis

• Provides equivalent of SPF 3 photoprotection • (the industry’s widely promoted pre-holiday base tan)

Page 13: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Indoor Tanning- Science, Behavior and Policy:

New England Journal of Medicine, Sept, 2010

p53 and tanning response

Epidermis

Melanocyte

Keratinocyte

UV Radiation

Page 14: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Significance of p53 and

tanning response

Tanning response directly linked to

p53 tumor suppressor pathway

Tanning does not occur without DNA

damage

Tanning without risk of

carcinogenesis “may be scientifically

impossible”.

Page 15: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Vitamin D is an important compound for healthy bones

Like the sun, tanning beds can produce vitamin D

However, you cannot exactly measure or predict the dosage

resulting from tanning beds

You can get an adequate dosage of vitamin D just as effectively

from a bottle. This is both safer and cheaper than tanning.

Vitamin D

Page 16: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Melanoma in Canada

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Cases of Melanoma Per Year In Canada

1992-2006

Blue= All

Red=Males

Green= Female

Public Health Agency of Canada

Page 18: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Melanoma in 2010

Estimated new cases in 2010

5300 : 2900 (M) 2300 (F)

Estimated deaths 2010

920 : 580 ( M), 350 (F)

Canadian Cancer Society

Page 19: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

UV and Melanoma

Risk of MM highest in fair skin population

Melanoma development is associated most strongly with intense intermittent sun-exposure

More than 5 sunburns in adolescence more than doubles risk of melanoma

Psoriasis patients treated with longterm UVA had increased melanoma incidence

Incidence of MM increases the closer you live to equator

Page 20: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

The Tanning Bed Industry

Average number of tanning salons exceeded

Starbucks or MacDonalds in 116 US cities » American Journal of Preventive Medicine

Estimated 8 billion dollar a year industry in

North America

30-35 million visits/year to tanning facilities

Currently no federal regulation of the tanning

industry.

Page 21: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

How are tanning beds different from

other source of UV?

Page 22: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Capital Regional District, Victoria B.C

Tanning Bed Legislation: Protecting Youth Coast to Coast

Page 23: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Dangers of Indoor vs. Outdoor Tanning

16+

15

14

13

12

11

10

9

8

7

6

5

4

3

2

1

0

Extreme risk from

unprotected exposure

Little risk from

unprotected

exposure

No danger

0

2

4

6

8

10

12

14

16

UV Index in Victoria Ultraviolet Index

Victoria UV Index data was provided by the UVic Weather Station

Network. Data comes from 6 separate stations and is the average of

noon observations for each month.

High risk from

unprotected

exposure

Very high risk from

unprotected

exposure

(Indoor Tanning Bed)

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UVA mediated damage

Moulin G, Thomas L, Vigneau M, et al. A case of unilateral elastosis with cysts and comedones: Favre-Racouchot syndrome. Ann Dermatol Venereol. 1994;121:721-723.

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Mother uses tanning beds five times a week.

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0

6

5

39

37

26

35

43

0

5

10

15

20

25

30

35

40

45

50

1980 1986 1988 1990 1995 2000 2005 2010

Year

Number of Indoor Tanning Facilities in Greater Victoria -

Select Years from 1980 to 20101

1Source: Yellow Pages telephone directory listings

Tanning Bed Legislation: Protecting Youth Coast to Coast

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Page 28: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Evidence for tanning beds

causing melanoma

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In the past 5 years, research into the dangers of indoor tanning has doubled:

1

0

20

40

60

80

100

120

140

160

180

Nu

mb

er

of

Se

arc

h R

esu

lts

PubMed Search Results for "tanning" per year from 1970 to

2009

1 Source: Pubmed Website (http://www.ncbi.nlm.nih.gov/pubmed)

Page 30: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

The estimated risk of melanoma highest for women who reported having sunburns

during adolescence

( 10–19-year age period)

RR 2.7 for > 2 burns per year

Overall, regular solarium use (i.e., one or more times per month) at any age was

associated with a statistically significant increased melanoma risk

RR 1.55 (55%)

Earlier Studies

• Journal of the National Cancer Institute, Vol. 95, No. 20,

October 15, 2003

Page 31: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Ever use associated with melanoma

(RR 1.15 )

–15% increase; based on 19 studies

First exposure to sunbeds before age

35 significantly increased risk of

melanoma (RR 1.75)

– 75% increase; based on 7 studies

(7355 cases)

The association of use of sunbeds with cutaneous malignant

melanoma and other skin cancers: A systemic review.

Int. J. Cancer: 120,1116-1122 (2006)

Page 33: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Why Advocate for this Ban?

This youth prohibition is based on the advice of credible,

non-partisan medical groups, including:

The World Health Organization (WHO)

The International Agency for Research on Cancer

(IARC)

The Canadian Medical Association (CMA)

The Canadian Dermatology Association (CDA)

The Canadian Cancer Society

The Canadian Paediatric Society

Why Youth?

Page 34: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

1: Increased Biological Susceptibility

Studies have found that those under 30 are at a higher risk

of developing skin cancer

If you use an indoor tanning facility under that age, you are

75% more likely to develop melanoma

Why Youth?

Page 35: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

2: Cumulative Exposure

Exposure is cumulative

The younger you start, the longer the potential tanning

period

The longer the tanning period, the higher your risks of

developing cancer

Preventing tanning for several years in the period during

which skin is at its most vulnerable is a definite benefit

Why Youth?

Page 36: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

3: Prevent Habit Formation

Habits developed in the teen years are often made without

full information

Further, these habits are much more difficult to quit later in

life

A 2009 Minnesota study found that those who begin tanning

younger tan much more frequently than those who start later

in life (34 vs 9 hours)

Why Youth?

Page 37: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

4: Adult Decision

Like tobacco and alcohol use, indoor tanning is a

pleasurable activity with no unique health risks (except in

cases of psoriasis)

Like tobacco and alcohol use, the potentially harmful effects

of tanning are usually seen much further on in life

It is difficult for teens to consider effects which occur later in

life

Removes peer pressure from the equation

Why Youth?

Page 38: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Why an Age Restriction?

A prohibition is intended to protect youth and public health has that

mandated role.

An age restriction is the only sure-fire way to accomplish the

objective.

There is no unique reason for UVR exposure therapeutically

except in cases of psoriasis and only administered in the hands of

a professional to the affected area in a metered dose.

Any benefit attributed to a tan can be more safely achieved through other

means

Parental consent is difficult to monitor and enforce and they may

not make their choices based on health considerations. They may

be less effective in protecting the health of youth than a ban.

Page 39: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Indoor Tanning Minors Regulation World Wide

The CRD was not be the first region to regulate the use of indoor tanning beds by

minors .

Page 40: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

2005 Ipsos-Reid

In 2005 VIHA requested an Ipsos-Reid poll to examine

support for an age ban of indoor tanning.

When first asked whether they supported an age ban:

55% supported the ban

When informed that the WHO considers indoor tanning to

be a carcinogen and then asked whether they supported an

age ban:

64% supported the ban

Page 41: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Legal Mandate and Implementation Strategy

Bylaw vetted by CRD lawyers

CRD as Board of Health has authority to enact health bylaws after

consultation

Ministry of Healthy Living and Sport Approval of Bylaw

Enactment date – following public education program

Enforcement by VIHA environmental health officers

Costs of enforcement will be minimal or non-existent

Page 42: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

www.suntips.ca

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Page 44: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

E-Holiday cards

Tanning Bed Legislation: Protecting Youth Coast to Coast

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Page 46: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Tanning, whether by sunlight or sunbed,

may cause premature aging of the skin

and skin cancer.

Tanning is not required to generate

Vitamin D.

Vitamin D levels in the body may be

increased by oral supplements without

tanning.

Joint Canadian Tanning

Association Website Disclaimer

Page 47: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Cdn Competition Bureau/

U.S. Federal Trade Commission

Fabutan, Edmonton, AB Penalty $85K

“Fabutan agrees to stop promoting

unproven health benefits of indoor

tanning”….. 2006

Indoor Tanning Association, Mass., USA

“Ordered to stop false and fraudulent

heath claims” ….. 2010

Page 48: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

JCTA Responds to IARC and WHO

Critique of the International Agency for Research

on Cancer meta-analysis of the association of

sunbed use with risk of cutaneous malignant

melanoma; Dermato-Endocrinology, Dec 2009

William Grant; non-physician, vit D researcher

Conclude that IARC studies show association, not

causality

Removal of confounding variables makes risk of

MM lower

Page 49: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Analysis of Analysis

Senior Epidemiologist, Cancer Care Nova Scotia

Grant:

Consistently misquotes IARC evaluation of the evidence of causality

Removes studies from analysis without clear reasons, except they demonstrated strongest association

No justification for analysis models applied to data

Has not carried out new analysis nor adjusted for any new confounders

Page 51: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Industry blogs

“If they don’t start tanning for high school prom

they will never be a customer”

Tan Today blog, July 20, 2011

Fabutan in Edmonton AB tans a ‘ginger’

“I am a ginger (red hair)…The staff were super

friendly in determining the time and lotions to

use”

YELP Review – Fabutan Sun Tan

Studios, July 21, 2011

Page 52: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

JUNIOR FUN TAN

By Elsa Akesson on

May 3, 2012

Shirley McInnis, public relations

manager at Beach Front, believes

the tanning bed market has been

calling for kid-sized beds for some

time. “You’d be surprised how

many requests we’ve had for kids’

beds. They see mommy and daddy

tan, and little Bobby and Susie want

to be tan too. It’s their right as

citizens to look nice and golden

through the winter without having to

go to Florida. Not everyone has a

condo in Naples. This is an

affordable option for families.”

Page 53: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Speak to Youth psychology

Page 54: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

THEN WE LISTENED TO YOUTH

Page 56: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Teen tan ban coming soon in Victoria

Enforcement targeted for 2012 after CRD passes bylaw

Sandra McCulloch

Times Colonist Thursday, October 13, 2011

Anyone 18 years of age or younger will soon be banned from using a tanning bed in

Greater Victoria.

The Capital Regional District board passed a bylaw Wednesday implementing the

ban, which is expected to come into effect in 2012.

Before the ban is enforced, the CRD will roll out an education program explaining its

reasons for the ban.

The Joint Canadian Tanning Association opposed the CRD's bylaw, saying a tan

acts as a natural sunscreen and a ban trumps parental rights.

Page 57: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Momentum

Vancouver and Fraser Health

Authorities proceed with intent to

Teen prohibition bylaws with

assistance from the CRD.

Effective use of Union of BC

Municipalities (UBCM) meeting to call

for Provincial Law.

Page 58: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

By Natalie North - Oak Bay News

Published: March 21, 2012 4:00 PM

Updated: March 21, 2012 4:22 PM

Oak Bay High students have stood out for passionately opposing tanning beds,

but it won’t be long before they’re in the same boat as teens across B.C.

The Ministry of Health announced a province wide ban on tanning bed use by

people under the age of 18 – a change directly linked to the tan-free movement

that began in Oak Bay.

Stephanie Wong and Adele Green, co-founders of the school’s Youth Against

Cancer club, were “ecstatic” to hear Health Minister Michael de Jong’s

announcement Tuesday morning. Wong and Green were among the first to bring

the issue of banning commercial tanning bed use in the Capital Regional District

before the CRD board of directors in 2010.

B.C. Health minister Michael de

Jong bans teens from tanning

University of Victoria students and former Oak

Bay High graduates Stephanie Wong, left, and

Adele Green are happy with the banning of

tanning booths for teens

Page 59: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

What can we learn from Tobacco?

Indoor UV exposure control in 2012

parallels Indoor Tobacco exposure

control efforts of the 1990s…

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Succinct health warnings?

Page 61: The Risks of Tanning Challenging the Myths, Confirming the ...€¦ · Objectives To understand photobiology of tanning from UV sources To understand why skin cancer is increased

Time to Register Tanning Salons/Beds ?

Registration like tobacco retailers.

Failure to comply – penalties to

include suspension of license to

operate.

Special tax/levy to pay for future

health costs (US 10% tax already).

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Take home points

Tanning beds are a risk factor for skin

cancer development

There is a significant knowledge gap

about risks of tanning, particularly in

promoters and users

Regulation of the tanning industry is a

necessary and responsible public

health measure

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Essential elements

Leadership/resources

Legal jurisdiction/mandate

Community support

Articulated risks/benefits

Know adversary (industry)

Build key alliances/diversified team

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Lessons Learned Many, many hands…

Dedicated resources…

Head, heart, gut - advocates, parents, youth, experts

Imagination…

Monitor the industry…

Stay focused on youth protection…

Youth - best to engage their peers and politicians – as affected audience…

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HTTP://PEDIATRICS.AAPPUBLICATIONS.ORG/CON

TENT/EARLY/2011/02/28/PEDS.2010-3501

Policy Statement—Ultraviolet Radiation: A Hazard to

Children and Adolescents

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THANK YOU