the pain reflex

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The pain withdrawal reflex is a rapid, unconscious response to danger or injury. It is mediated by the spine’s grey matter. . The Pain Reflex. A very basic overview from the BBC: . - PowerPoint PPT Presentation

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Page 1: The Pain Reflex
Page 4: The Pain Reflex

The Pain Reflex The pain withdrawal reflex is a rapid, unconscious response to danger or injury. It is mediated by the spine’s grey matter.

(nociceptors)

Page 5: The Pain Reflex

The Pain Reflex The pain withdrawal reflex is a rapid, unconscious response to danger or injury. It is mediated by the spine’s grey matter.

Injury stimulates pain receptors (nociceptors), causing Ca2+ ions to rush in. This depolarises the sensory neuron and starts an action potential.

(nociceptors)

propagates the AP along theaxon (review action and resting potentials!)

Page 6: The Pain Reflex

The Pain Reflex The pain withdrawal reflex is a rapid, unconscious response to danger or injury. It is mediated by the spine’s grey matter.

Relay neurons (interneurons in the animation above) are in the grey matter of the spine. They receive the signal from the sensory neuron, through synaptic transmission (review it!) and coordinate the response to pain:

• An excitatory neurotransmitter (e.g. ACh) is sent across the next synapse to the motor neuron for muscles to contract.

• An inhibitory NT is used to send a signal to antagonistic (opposite) muscles to relax.

Page 7: The Pain Reflex

Spine-mediated pain reflex arc, from: http://en.wikibooks.org/wiki/Anatomy_and_Physiology_of_Animals/Nervous_System

The Pain Reflex The pain withdrawal reflex is a rapid, unconscious response to danger or injury. It is mediated by the spine’s grey matter.

(nociceptors)

Finally, the motor neurons conduct the AP from the relay neuron to the effector (muscle). • Muscles that need to contract

receive and excitatory signal. • Muscles that need to relax

receive an inhibitory signal.

The response is rapid movement away from the source of pain.

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