the european society for vascular surgery 4 spring … · the european society for vascular surgery...
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TheEuropeanSocietyforVascularSurgery 4thSpringMeeting
UCLInstituteofChildHealth,London,UK13th–14thMay2016
PROGRAMMEandABSTRACTS2016
www.esvs.org
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Welcometothe4thESVSSpringMeetinginLondonin2016!Thankyouforjoiningusforthe4thESVSSpringmeeting.
Last Spring, we came together in Frankfurt for 2 days of lively discussions on leading
researchinvascularbiology,novelmaterialsandinnovativedevicescoveringallaspectsof
vasculardisease.
This year, we continue our focus on translational vascular research with 5 scientific
sessions coveringmolecular and cellular biology of vascular diseases, vascular imaging,
vascular modelling, biomaterials and cardiovascular device. There is also a dedicated
poster session and authors of the 5 best posters will be invited to give short oral
presentationsoftheirworkonSaturdayincompetitionfortheposterprize.Thankyouto
everyonewhohassubmittedtheirworktothemeeting.
Wearealsoexcitedtowelcomeourkeynotespeakerswhowillupdateusontheir latest
work,andgiventheincreasingimportancecross-disciplinaryprojects,wehavealsoasked
Tom Schmitz-Rixen to give us his views on the challenges of cross-disciplinary
collaborations.
The networking dinner has always been a fun opportunity to learn more about each
other’sworkanddevelopandconsolidatecollaborations:pleasejoinusforthis.
Thankyouforyoursupportandinput.Wehopeyouwillenjoythemeeting.
JaniceTsui,GeorgeHamilton,ThomasSchmitz-Rixen,JaapHamming,SebastianDebus
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ProgrammeOverview
Friday,13thMay2016
10:45 OpeningCommentsMissJaniceTsui,LocalOrganisingCommittee
ProfMarkEmberton,Dean,FacultyofMedicalSciences,UCL
11:00 Keynotelecture:
VascularAging:Theroleofnon-codingRNA
DrReinerBoon,InstituteofCardiovascularRegeneration,GoetheUniversityFrankfurt/M,Germany
11:25-12:55 OralSession1:MolecularandCellularBiologyofVascular
Diseases
12:55–13:45 Lunch
13:45 Keynotelecture:
Multi-scalemodellingtounderstandatherosclerosisandcalcificationlocations:
comparisonwithin-vivodata
DrVanessaDiaz,DepartmentofMechanicalEngineering,UniversityCollegeLondon,UK
14:10–15:10 OralSession2:VascularImaging
15:10–15:40 Coffeebreak
15:40-15:55 Invitedtalk:
Challengesofcross-disciplinaryresearch
ProfThomasSchmitz-Rixen,DepartmentofVascular&EndovascularSurgery,Goethe-University
Hospital,Frankfurt,Germany
15:55–17:15 OralSession3:VascularModelling
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17:15–19:00 PosterSession
20:00 NetworkingDinner
Saturday,14thMay201608:30 Keynotelecture:
VenousStents–DesignOptimizationfortheClinicalChallengeDrStephenKao,VicePresidentofR&D,Veniti,Inc.
08:55–10:05 Oralsession4:Biomaterials
10:05-10:20 Coffeebreak
10:20 Keynotelecture:
MolecularAspectsofVascularRemodelling
ProfPaulQuax,EinthovenLaboratoryforExperimentalVascularMedicine,LUMC,theNetherlands
10:45-11:25 Posterprizesession
11:25-11:35 Coffeebreak
11:40 KeynotelectureandIntroductiontoISACB
HumanMesenchymalStemCell-BasedTissueEngineeredVascularGraftsProfDavidA.Vorp,UniversityofPittsburgh,USA
12:00-13:20: OralSession5:CardiovascularDevices
13:20 ClosingRemarks
Prof.TSchmitz-Rixen
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FullProgramme
Friday,13thMay2016
10:45 OpeningCommentsMissJaniceTsui,LocalOrganisingCommittee
ProfMarkEmberton,Dean,FacultyofMedicalSciences,UCL
11:00 Keynotelecture:
VascularAging:Theroleofnon-codingRNA
DrReinerBoon,InstituteofCardiovascularRegeneration,GoetheUniversityFrankfurt/M,Germany
11:25-12:55 OralSession1:MolecularandCellularBiologyofVascular
Diseases
Chairs:DrReinerBoon,Frankfurt,Germany&DrMarkellaPonticos,London,UK
11:25 TaisiyaBezhaeva,TheNetherlands
OpposingeffectsofTLR4homologueRP105onVSMCproliferationandmacrophage
polarizationinamurinemodelofarteriovenousfistulafailure
11:35 LukeBrewster,USA
ImpactofAgingonMurineElasticandMuscularArteries
11:45 CharlotteLawson,UK
Effectofdiabetesonwoundhealingandcirculatingmicrovesiclesinaninvivoischaemic
woundmodel
11:55 AlexanderGötze,Germany
HigherconcentrationsofIL10improvehindlimbreperfusionrecoveryinmiceafter
femoralarteryligation
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12:05 RobdeJong,TheNetherlands
Inhibitionofthe14q32microRNA-495reduceslesionformation,intimalhyperplasiaand
plasmacholesterollevelsinmousemodelsforpost-interventionalrestenosisand
atherosclerosis
12:15 KerstinTroidl,Germany
Contributionofsmoothmusclecell-derivedandendothelialcell-derivedmiRNAsduring
vascularremodeling
12:25 MuholanKanapathy,UK
Connexinasabiomarkerforvenousulceration
12:35 NinaMzhavanadze,Russia
Long-termeffectsandpharmacokineticstudiesofnakedplasmidDNAencodingvascular
endothelialgrowthfactorisoformVEGF165transferinpatientswithatherosclerotic
peripheralarterialdisease
12:55–13:45 Lunch
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13:45 Keynotelecture:
Multi-scalemodellingtounderstandatherosclerosisandcalcificationlocations:
comparisonwithin-vivodata
DrVanessaDiaz,DepartmentofMechanicalEngineering,UniversityCollegeLondon,UK
14:10–15:10 OralSession2:VascularImaging
Chairs:Prof.SebastianDebus,Hamburg,Germany&Prof.SebastienOurselin,London,UK
14:10 UlrichRother,Germany
Immediatechangesoftissueperfusionduringtibialangioplasty–measurementswith
respecttoangiosomes
14:20 CraigGoergen,USA
UltrasoundandMagneticResonanceImagingofMurineAbdominalAorticAneurysms
14:30 AlexanderRolls,UK
AComparisonofImage-versusHardware-basedTrackingTechnologiesin2D-3DFusion
inAorticEndografting
14:40 WojciechDerwich,Germany
Kinematicevaluationofinfrarenalaorticaneurysminstabilityusing4Dultrasound
14:50 InezTorres,Brazil
Simulatorfortraininginendovascularinfra-renalaneurysmrepair:theuseof3Dprinters
15:00 SteveGreenwald,UK
Non-contactmeasurementofcarotidarterywallmovementfordiagnosisofvascular
disease
15:10–15:40 Coffeebreak
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15:40-15:55 Invitedtalk:
Challengesofcross-disciplinaryresearch
ProfThomasSchmitz-Rixen,DepartmentofVascular&EndovascularSurgery,Goethe-University
Hospital,Frankfurt,Germany
15:55–17:15 OralSession3:VascularModelling
Chairs:DrVanessaDiaz,London,UK&MrDaryllBaker,London,UK
15:55 JacobSalmon,UK
PhysiologicalvorticesinthesinusesofValsalva:aninvitroapproachforbio-prosthetic
valves
16:05 BahaaNasr,France
Characterizationofthephysiologicalmotionoftheaorticarchandthesupra-aortic
vessels.
16:15 ObiekezieAgu,UK
Patient-specificComputationalmodellingofWallMotioninAorticDissectionusingFluid-
StructuralInteraction
16:25 BenjaminObukofe,UK
PrognosticRiskFactorsUnderlyingAbdominalAorticAneurysm(AAA)Growth
16:35 AndreasWittek,Germany
AMethodforVirtualHypertonicStressTestsofAAAUsingPatient-IndividualFinite
Element-Analyses
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16:45 BenjaminObukofe,UK
AGeneticRiskScore-BasedNomogramtoPredictAbdominalAorticAneurysm(AAA)in
theCaucasianEuropeanPopulation
16:55 SmiljanaDjorovic,Serbia
Athree-dimensionalcomputationalanalysisofbloodflowinpatient-specificaorticstent
graft
17:05 CunnaneConnor,Ireland
APreliminaryStudytoDetermineIfArteriovenousFistulaConfigurationGeneratesHelical
Flow
17:15–19:00 PosterSession
1. GaryBowlin,USA
ANewPerspectiveontheNeutrophilandItsExpandingRoleintheInnateImmune
ResponsetoBioresorbableVascularGraft
2. DebraChong,UK
EngineeringVascularGraftNanopitSurfaceTopography:EffectsonEndothelialCell
Adherence
3. HendrikVanDamme,Belgium
LateFateofcryopreservedarterialAllografts
4. TimothyPennel,SouthAfrica
Transmuralcapillaryingrowthisessentialformid-grafthealing
5. FelixRuben,Argentina
AutologusDermoepidermaldevice(ADED)producedbytissueengineering
6. FlorianStefanov,Ireland
PrimaryversussecondaryinterventionevaluationfortwelveaortictypeBdissections
managedwiththestreamlinermultilayerflowmodulator
7. IharaTsutomu,Japan
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PostoperativechangesinthediameterofthedistallandingzoneafterEVARintroduction
andobjectives
8. GagandeepGrover,UK
CerebralEmbolicProtectiontoinThoracicEndovascularAorticRepair(TEVAR)–APilot
Study
9. HarriHakovirta,Finland
CardiovascularRiskFactorsDifferinInflammationPathologyinPatientswithClinically
SymptomaticLowerLimbAtherosclerosis
10. EoghanCunnane,Ireland
TheMechanical,CompositionalandMorphologicalCharacterisationofFemoral
AtheroscleroticPlaquefortheContinuedImprovementofEndovascularTreatment
11. FlorianSimon,Germany
TimedependencyofH2S-inducedorganprotectionduringlong-termresuscitatedporcine
haemorrhage
12. KonstantinosPapoutsis,Greece
Theroleofrelaxininvasculardiseases:earlyresults
13. BodnarPetro,Ukraine
Assessmentofindicatorsendothelialdysfunctioninpathogenesispost-thrombotic
syndrome
14. ZuzannaRowinska,Germany
TheroleofMMP2indevelopmentofaneurysmincombinationwiththetransplantation
model
15. DanilaKozhevnikov,Russia
Comparativeimageofpigaortaandhumanrupturedabodminalaortabynewhigh
resolutionx-raymicrotomography
16. BenjaminObukofe,UK
MethyleneTetrahydrofolateReductaseC677T(MTHFRC667T)GeneticPolymorphismisa
PrognosticRiskFactorforAbdominalAorticAneurysm(AAA)
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17. BenjaminObukofe,UK
Mechanismofinteractionofangiotensinconvertingenzymeinsertion-deletion
polymorphismwithmethylenetetrahydrofolatereductaseC677Tgeneticpolymorphisms
inthepathogenesisofabdominalaorticaneurysms
18. ChristianGasser,Sweden
Localparametersthatinfluencethelocalgrowthofabdominalaorticaneurysms
19. StephanieTomee,TheNetherlands
Howdoesitfeeltohaveanabdominalaorticaneurysm–apatient-centeredview
20. MeritxellDavins,Spain
Useoftelemedicinetohelpcontrolofperipheralarterialdisease
21. IkeOkonji,UK
TheuseofCTimagingtoidentifythehighriskcarotidplaque
22. PragashKamalathevan,UK
Plaqueulcerationisassociatedwithsymptomaticcarotidarterydisease
23. SusanneRegus,Germany
TimingoffirstAVFscannulationinchildrenonhemodialysis
24. SusanneRegus,Germany
MRItoinvestigateiliacarterywallthicknessintriathletes
20:00 NetworkingDinner
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Saturday,14thMay201608:30 Keynotelecture:
VenousStents–DesignOptimizationfortheClinicalChallenge
DrStephenKao,VicePresidentofR&D,Veniti,Inc.
08:55–10:05 Oralsession4:Biomaterials
Chairs:DrStephenKao,Veniti&DrWenhuiSong,London,UK
08:55 JunHongPang,UK
DevelopmentofPre-polymerCoatingswithPro-endothelialisationPotentialfor
CardiovascularDevices
09:05 LazarenkoGleb,Ukraine
Modifikationofthestentssurfacebytreatmentwithautoalbuminforpreventionofthe
bodyreaction
09:15 JunjieZhao,UK
Nano-surfacePatternedCoatingPromotesin-situEndothelizationforStents
09:25 DebraChong,UK
Nanotopographicalgraftsurfacemodulationtopromoteendothelialisationmaypromote
calcificationbydirectingmesenchymalstemcellstoanosteogeniclineage
09:35 YasminFarhatnia,UK
DevelopmentofPediatriccoveredstentusingnanocompositematerial
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09:45 AllisonFetz,USA
ElectrospunVascularGraftArchitectureandCompositionRegulatesNeutrophilNETosisIn
Vitro:APotentialPredictorofSuccessorFailure
09:55 PopovGury,Russia
Isitpossibletocreatereadilyavailabletissue-engineeredvasculargraftswithoutusing
cells?
10:05-10:20 Coffeebreak
10:20 Keynotelecture:
MolecularAspectsofVascularRemodelling
ProfPaulQuax,EinthovenLaboratoryforExperimentalVascularMedicine,LUMC,TheNetherlands
10:45-11:25 Posterprizesession
Chairs:ProfPaulQuax,TheNetherlands&DrBrianCousins,UK
11:25-11:35 Coffeebreak
11:40 KeynotelectureandIntroductiontoISACB
HumanMesenchymalStemCell-BasedTissueEngineeredVascularGrafts
ProfDavidA.Vorp,UniversityofPittsburgh,USA
12:00-13:20: OralSession5:CardiovascularDevices
Chairs:Prof.DavidVorp,PresidentofISACB,USA&Prof.LukeBrewster,USA
12:00 MichaelGawenda,Germany
Fromtheworkbenchtothehumanbody-Influenceof3-DimensionalAorticmodelon
CasePlanningforFEVAR
12:10 MarcoHorn,Germany
3-DModelingoftheAbdominalAortaforExperimentalEndovascularNavigation
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12:20 Pierre-JeanCottinet,France
Inkjetprintingbasedelectroactivepolymerforsteerableandhapticfeedbackofguidewire
12:30 SelimBozkurt,UK
DevelopmentandHydrodynamicAssessmentofaNovelTranscatheterMitralValve
12:40 MitalDesai,UK
MechanicalprofileofathoracicendograftdevelopedusingPOSS-PCUandshapememory
alloy
12:50 SebastianDebus,Hamburg,Germany
TheHamburgHybridGraft–atechnicalfeasibilitystudyforthoracoabdominalrepairin
pigs
13:00 SabineWipper,Germany
Completepercutaneoustransapicalinstrumentationforsingle-sidebrancharchendograft
usingapercutaneousclosuredeviceinpigs
13:10 RobKrams,UK
MechanosensitivesignallingpathwaysadaptduringTCFAformation
13:20 ClosingRemarks
Prof.TSchmitz-Rixen