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save valuable time placing titles, subtitles, text, and graphics.

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Acute Rhinosinusitis

• Sudden onset of symptoms (<12 weeks) include

anterior/posterior mucopurulent discharge PLUS

nasal obstruction/pressure/pain

• RS is the 5th most common diagnosis in the U.S.

for which antibiotics are prescribed

• Typically viral etiology, but can be bacterial,

fungal or allergic

• Regardless of etiology, antibiotics are prescribed

to 85-98% of patients in the US

Antibiotics

• Antibiotics have been the standard treatment for

Acute Rhinosinusitis even though the typical

etiology is viral2. With the rise of antibiotic

resistant organisms, exploring other potential

treatment options is important and necessary.

Physical activity

• Physical activity has long been known to improve

the general health of individuals who routinely

engage in it1.

• Several recent studies have shown that

consistent physical activity can improve the

course of several chronic diseases such as

cancer1, diabetes1, and heart disease1.

• We hope to determine if chronic physical activity

can improve the course of acute cases of

rhinosinusitis.

Introduction

Methods

Setting

Patients reporting to the clinic with nasal obstruction or facial

pain/pressure/fullness AND anterior or posterior mucopurulent drainage

were enrolled as patients with acute rhinosinusitis. Patients presenting

to the clinic without those symptoms were enrolled as healthy controls.

Patients were then asked to report their level of physical activity within

the last 6 months and were divided into only 4 groups based on level of

physical activity. Patients then monitored and recorded their symptoms

every morning and evening for 1 week using the SNOT-20

questionnaire.

Our hypothesis is that a recent history of routine physical activity will

reduce symptom severity, time to symptom resolution, and inflammatory

markers in patients with acute rhinosinusitis in comparison to patients

who do not routinely exercise.

The Effects of Routine Exercise on Acute Rhinosinusitis Hayden White OMS-II; Chelsea Weidman, M.S.; Jillian Bradley Ph.D.

The study is being performed at two sites of a direct-

payment outpatient clinic. Both sites are in the same mid-

sized, manufacturing and industrial, rural town.

Hypothesis

Edward Via College of Osteopathic Medicine – Carolinas Campus

Demographics

Inclusion Criteria Exclusion Criteria

Ages 18-70 Temperature ≥ 102.5°F

Presenting with acute RS Used topic antibiotics within last 30

days

OR Healthy (control) Taken oral antibiotics within last 15

days

Independently read the informed

consent form

Has a comorbidity, taking antibiotics

or antiviral therapy

Needs to be hospitalized

Is currently pregnant, nursing or

suspect they may be pregnant

Bone fractures to the face or neck

Visible nasal polyps, abscesses,

incisions

Patient eligibility

Category Amount of physical

activity

Minimal Physical Activity >30 minutes a week

Mild Physical Activity 30 minutes 1-2 days a

week

Moderate Physical Activity 30 minutes 3-4 days a

week

Heavy Physical Activity <1 hour 4 or more days a

week

Physical activity categories

TAP TO GO

BACK TO

KIOSK MENU

QUICK START (cont.)

How to change the template color theme You can easily change the color theme of your poster by going to the DESIGN

menu, click on COLORS, and choose the color theme of your choice. You can

also create your own color theme.

You can also manually change the color of your background by going to VIEW >

SLIDE MASTER. After you finish working on the master be sure to go to VIEW >

NORMAL to continue working on your poster.

How to add Text The template comes with a number of pre-formatted placeholders for headers

and text blocks. You can add more blocks by copying and pasting the existing

ones or by adding a text box from the HOME menu.

Text size Adjust the size of your text based on how much content you have to present. The

default template text offers a good starting point. The text should not be less than

28 points.

How to add Tables To add a table from scratch go to the INSERT menu and

click on TABLE. A drop-down box will help you select rows and

columns.

You can also copy and a paste a table from Word or another PowerPoint

document. A pasted table may need to be re-formatted by RIGHT-CLICK >

FORMAT SHAPE, TEXT BOX, Margins.

Graphs / Charts You will have to convert your graphs/charts/formulas/equations into images (.jpg

or .png and insert them into your presentation. This will help maintain the values

as different operating systems can distort your work.

Save your work Save your template as a lastname.firstname and as a .pptx file.

This is an ePosterBoards template www.eposterboards.com

(—THIS SIDEBAR DOES NOT SHOW—)

DESIGN GUIDE

This PowerPoint 2016 template produces a 40.97X23.04”

presentation poster. You can use it to create your research poster and

save valuable time placing titles, subtitles, text, and graphics.

We provide a series of YouTube tutorials that will guide you through

the poster design process and answer your poster production

questions. To view our template tutorials, go online to

https://www.youtube.com/playlist?list=PLBz4JvE0AKmweXsMNGeyR

XgWgN_lj_b5L

If you are uploading ahead of time, please go to our website:

http://www.eposterboards.com/eposterupload/

Need assistance? Call us at 617-588-3508 option 2

QUICK START

Title, Authors, and Affiliations Start designing your poster by adding the title, the names of the authors, and the

affiliated institutions. You can type or paste text into the provided boxes. The

template will automatically adjust the size of your text to fit the title box. You can

manually override this feature and change the size of your text.

TIP: The font size of your title should be bigger than your name(s) and institution

name(s). The smallest font size should be 28 points.

Adding Logos / Seals Most often, logos are added on each side of the title. You can insert a logo by

dragging and dropping it from your desktop, copy and paste or by going to

INSERT > PICTURES. Logos taken from web sites are likely to be low quality

when printed. Zoom it at 100% to see what the logo will look like on the final

poster and make any necessary adjustments.

TIP: If there is a conference website, you can pull logos from there. Please

keep in my that we will be adding navigational buttons or a kiosk menu button on

the right side of the slides. Please make the appropriate space for that.

Photographs / Graphics You can add images by dragging and dropping from your desktop, copy and

paste, or by going to INSERT > PICTURES. Resize images proportionally by

holding down the SHIFT key and dragging one of the corner handles. For a

professional-looking poster, do not distort your images by enlarging them

disproportionally.

ORIGINAL DISTORTED

www.eposterboards.com

Results

Edward Via College of Osteopathic Medicine – Carolinas Campus

Hayden White OMS-II; Chelsea Weidman, M.S.; Jillian Bradley Ph.D.

The Effects of Routine Exercise on Acute Rhinosinusitis

Results Continued Discussion

Figure 1. The effect of physical activity level on

IL-6 in patients with and without acute

rhinosinusitis. Patients with and without acute

rhinosinusitis were enrolled in the study. Blood was drawn

at the time of presentation, and systemic IL-6 levels were

determined via ELISA. Patients also reported their level of

physical activity within the last 6 months. Data is

represented as a mean + SD. * indicates a p-value of 0.05

In looking at the IL-6 cytokine when patients were

first enrolled in the study we did find that baseline

levels of IL-6 were decreased as engaged in

greater levels of physical activity. This information

is consistent with the current literature which

shows that healthy individuals have lower levels of

chronic inflammation. However, there was no

statistically significant difference between healthy

controls and sick patients within the same physical

activity group.

Figure 2. The effect of physical activity level on

symptom severity during acute rhinosinusitis. Patients with and without acute rhinosinusitis were enrolled in

the study. Patients reported their level of physical activity

within the last 6 months. Patients were also asked to report

their symptom severity using the SNOT-20 questionnaire.

This is a 20 parameter questionnaire that ranks symptoms in

a score of 0-5 where 0 is “not a problem at all” and 5 is “the

worst possible.” The scores are then added together with a

total possible total symptom score (TSS) of 100. Data is

represented as a mean + SD. * indicates a p-value of 0.05

There is a statistically significant difference in

symptom severity in patients with acute

rhinosinusitis for every level of physical activity. In

addition, the average TTS was similar across all

exercise groups. This result indicates that in terms

of the patients perceived symptom severity, a history

of exercise does not significantly effect how patients

feel when initially diagnosed with acute

rhinosinusitis.

Figure 3. The effect of facial effleurage on

patients with different physical activity levels

during acute rhinosinusitis. Patients with and without

acute rhinosinusitis were enrolled in the study. Patients

reported their level of physical activity within the last 6

months. Patients were also asked to report their symptom

severity using the SNOT-20 questionnaire. This is a 20

parameter questionnaire that ranks symptoms in a score of

0-5 where 0 is “not a problem at all” and 5 is “the worst

possible.” The scores are then added together with a total

possible total symptom score (TSS) of 100. The patients

were then randomized into one of 8 treatment groups. Some

groups received antibiotics. Some groups received Facial

Effleurage. Some groups received a sham treatment called

physical touch control. One hour after treatment began, the

post-treatment TSS was collected. The post-treatment TSS

was subtracted from the pre-treatment TSS for each patient.

Data is represented as a mean + SD. * indicates a p-value of

0.05

The larger decrease in TSS indicates a greater

resolution of symptoms after 7 days. As shown,

patients in the facial effleurage groups showed the

greatest symptom reduction. Among those patients,

most patients with more than minimal physical

activity had the greatest reduction of symptoms.

Ultimately, more data is needed before

drawing definitive conclusions. However,

we are seeing data that corresponds with

the literature indicating a decrease in

chronic inflammation and general feelings

of malaise in healthy individuals who have

higher levels of routine physical activity.

We are also seeing some encouraging

signs that more than minimal physical

activity can aid in the resolution of

symptoms in acute rhinosinusitis. When

collecting our data, one of the biggest

weaknesses was the fact that patients self

report their level of physical activity. This

can easily lead to patients exaggerating

their activity levels as well as confusion

regarding different definitions of physical

activity. However, we hope that by have

fairly broad categories for physical activity

we can minimize these reporting errors.

References

1. Warburton, D. E.r. “Health Benefits of Physical Activity: the Evidence.”

Canadian Medical Association Journal, vol. 174, no. 6, 2006, pp. 801–

809., doi:10.1503/cmaj.051351.

2. Young, Jim, et al. “Antibiotics for Adults with Clinically Diagnosed Acute

Rhinosinusitis: a Meta-Analysis of Individual Patient Data.” The Lancet,

vol. 371, no. 9616, 15 Mar. 2008, pp. 908–914., doi:10.1016/s0140-

6736(08)60416-x.