the detergent industry’s - aise...the detergent industry’s challenges under clp assuring...

The detergent industry’s

challenges under CLP

Assuring appropriate skin and eye classifications

Gerard Luijkx, Unilever, Chairman of the AISE C&L SG

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Industry’s objective:

2

Safe use of our

products

Appropriate

Classification &

Labelling

Transparent process Legal robustness

Sound Science Consistent within the

sector

Optimal use of data

●

CLP: Several classification challenges

• Environment: introducing chronic classification for readily

(bio)degradables

• Sensitisation: new skin sensitisation sub category 1A

• Corrosion to metals

• And last but not least: skin and eye irritation/corrosivity

3

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CLP: data hierarchy

4

Data on the mixture itself*?

Data on similar tested mixtures

(bridging principles)?

Calculation based on

ingredient classification

*No human testing for classification

purposes, no new animal testing.

Data generation: in vitro methods

classify

classify

classify

Article 6 and Annex I

of CLP

http://www.google.nl/url?sa=i&rct=j&q=&esrc=s&frm=1&source=images&cd=&cad=rja&docid=zrhHcw_ImNkf2M&tbnid=XP6aV9751NDNgM:&ved=0CAUQjRw&url=http://forums.qj.net/general-off-topic/163594-pictogram-game.html&ei=3gzYUqTiOOiq0QXc54CgDg&psig=AFQjCNFsH4TMN6ZyQ3xTylQl9j9ILWzHGg&ust=1389976800379137

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DPD versus CLP

5

CLP introduced new classification criteria according to UN

GHS in Europe

The application of additivity principles of CLP often result

in a more severe classification for eye and skin hazards

when compared to the former Dangerous Preparations

Directive (DPD)

http://upload.wikimedia.org/wikipedia/commons/a/a1/GHS-pictogram-acid.svg//upload.wikimedia.org/wikipedia/commons/c/c3/GHS-pictogram-exclam.svghttp://www.google.nl/url?sa=i&rct=j&q=&esrc=s&frm=1&source=images&cd=&cad=rja&docid=zrhHcw_ImNkf2M&tbnid=XP6aV9751NDNgM:&ved=0CAUQjRw&url=http://forums.qj.net/general-off-topic/163594-pictogram-game.html&ei=3gzYUqTiOOiq0QXc54CgDg&psig=AFQjCNFsH4TMN6ZyQ3xTylQl9j9ILWzHGg&ust=1389976800379137

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Classification for eye irritation/corrosion

by calculation

6

DPD Classification threshold, Symbol,

indication of danger, Risk phrase

Concentration

%

CLP Classification threshold,

Pictogram, SIGNAL WORD, Category,

Hazard statements

≥ 10 %, „Irritant“

„Risk of serious damage to eyes“

10 –100 ≥ 3 % DANGER,

Eye Cat. 1

„Causes serious eye damage“

≥ 5 to < 10 %, „Irritant“

„Irritating to eyes“

5 – 10

0 to < 5 %: no labelling

3 – 5

1 – 3 ≥ 1 to < 3 % WARNING, Eye Cat. 2 „Causes serious eye irritation“

0 – 1 0 to < 1 %: no labelling

DPD versus CLP Calculation of mixture classification based on content of an Eye cat 1 ingredient

http://upload.wikimedia.org/wikipedia/commons/a/a1/GHS-pictogram-acid.svg//upload.wikimedia.org/wikipedia/commons/c/c3/GHS-pictogram-exclam.svghttp://www.google.nl/url?sa=i&rct=j&q=&esrc=s&frm=1&source=images&cd=&cad=rja&docid=zrhHcw_ImNkf2M&tbnid=XP6aV9751NDNgM:&ved=0CAUQjRw&url=http://forums.qj.net/general-off-topic/163594-pictogram-game.html&ei=3gzYUqTiOOiq0QXc54CgDg&psig=AFQjCNFsH4TMN6ZyQ3xTylQl9j9ILWzHGg&ust=1389976800379137

●

Classification for skin irritation/corrosion

by calculation

7

DPD versus CLP Calculation of mixture classifcation based on content of a Skin cat 1 ingredient

DPD Classification threshold, Symbol,

indication of danger, Risk phrase

Concentration

%

CLP Classification threshold,

Pictogram, SIGNAL WORD, Category,

Hazard statements

≥ 10 %, „Corrosive“,

„Causes burns“

+CRC and TWD

10 -100 ≥ 5 %

DANGER, Cat. 1;

„Causes severe skin burns and eye

damage“

+CRC and TWD ≥ 5 to < 10 %, „Irritant“

„Irritating to skin“

5 - 10

0 to < 5 %: no labelling 1 - 5 ≥ 1 % to < 5 %

WARNING, Cat. 2;

„Causes skin irritation“

0 - 1 0 to < 1 %:

no labelling

http://upload.wikimedia.org/wikipedia/commons/a/a1/GHS-pictogram-acid.svg//upload.wikimedia.org/wikipedia/commons/c/c3/GHS-pictogram-exclam.svg

●

Classification for eye irritation/corrosion

by calculation

8

Using calculation, a

majority of daily-use

detergents would be

classified Eye

Damage Cat 1 with

the same pictogram

as a drain cleaner

N

OW

P

AS

T

?


●

Very different hazard profile

same pictogram?

9


●

Classification for skin/eye

irritation/corrosion

10

Appropriate classification and labelling is essential for

safe use by consumers/users.

Truly hazardous products must be distinguished from

regular detergents to avoid:

• confusion between products’ hazards by consumers

• ‘Inflation’ of the importance of the hazard pictograms

• overtreatment in case of accidental exposure

Test data on mixtures have a higher likelihood to reflect

actual effects on man versus calculation


●

CLP: making good use of data hierarchy

11

Data on the mixture itself*?

Data on similar tested mixtures

(bridging principles)?

Calculation based on

ingredient classification

*No human testing for classification

purposes, no new animal testing.

Data generation: in vitro methods

classify

classify

classify

TEST THE MIXTURE

IN VITRO (or use

existing mixture data)

BRIDGING

PRINCIPLES

(to similar tested

mixtures e.g. DetNet)

CALCULATION

Article 6 of CLP

●

Thank you!

12

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