the aortic arches
DESCRIPTION
The Aortic Arches. Objectives. Describe the formation of the aortic arches. Enlist the derivatives of aortic arches. Discuss the development of venous system of the heart. Differentiate between fetal and neonatal circulation. Discuss the congenital anomalies of the aortic arches. - PowerPoint PPT PresentationTRANSCRIPT
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The Aortic Arches
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Objectives
Describe the formation of the aortic arches. Enlist the derivatives of aortic arches. Discuss the development of venous system
of the heart. Differentiate between fetal and neonatal
circulation. Discuss the congenital anomalies of the
aortic arches.
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Aortic Arches The aortic arches are a series of
paired arterial channels encircling the embryonic pharynx
They: Develop in the 4th week Supply the developing
pharyngeal arches Arise from the aortic sac Run dorsally, embedded in the
mesenchyme of the pharyngeal arches and
Terminate in the right and left dorsal aortae
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Develop in a craniocaudal sequence
There are potentially six pairs, but the fifth pair is poorly developed and disappears soon after formation
Not all the 6 pairs present at the same time. By the time the 6th aortic arches are formed, the 1st & 2nd have disappeared
In the region of aortic arches, the dorsal aortae remain paired, but caudal to this region they fuse to form a single median vessel
Aortic --sac
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During week 6 to 8, the primitive aortic arch pattern is transformed into the adult arterial arrangement of carotid, subclavian, and pulmonary arteries
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Derivatives of Aortic Arches
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First Pair Largely disappear Dorsal part persists
as the maxillary arteries which supply the ear, teeth and muscles of the eyes and face
May give rise to the external carotid artery The first arch is obliterated before
the 6th arch is formed
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Second Pair
Largely disappear Dorsal part persists
as the hyoid and stapedial arteries
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Third Pair
Proximal part: forms the common carotid arteries
Distal part: joins the dorsal aortae to form the internal carotid arteries
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Fifth Pair
Disappears completely with NO vascular derivatives
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The fate of 4 & 6th pairs of aortic arches differs on the right and left
side
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Fourth Pair
RIGHT: Becomes the proximal part of the right subclavian artery
LEFT: Forms part of the arch of aorta
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Arch of Aorta
Derived as: Proximal segment
from aortic sac Middle segment from
the left 4th aortic arch Distal segment from
the left dorsal aorta
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Subclavian Artery
The right subclavian artery formed from the: Right 4th aortic arch Right dorsal aorta & Right 7th
intersegmental artery The left subclavian
artery formed from the left 7th intersegmental artery
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Sixth Pair RIGHT:
• Proximal part: persists as the proximal part of the right pulmonary artery
• Distal part: degenerates LEFT:
• Proximal part: persists as the proximal part of the left pulmonary artery
• Distal part: forms ductus arteriosus, a shunt between pulmonary artery and dorsal aorta
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Changes in the original aortic arch system
Obliteration of:
1. Most of the 1st & 2nd arches
2. 5th arches completely
3. Distal part of the right sixth arch
4. The segment of both aortae lying between the 3rd & 4th arches
5. The segment of right aorta lying between the 7th intersegmental artery & the fused dorsal aortae
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Relation of recurrent laryngeal nerves to the aortic arches
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Anomalies of the Aortic Arches
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Coarctation of Aorta Characterized by narrowing of aorta More common in males Classified as Preductal & Postductal
types, but mostly the constriction lies distal to the origin of subclavian artery opposite the ductus arteriosus (Juxtaductal)
Preductal type: Less common. The narrowing is proximal to the
ductus arteriosus. If severe, blood flow to the aorta
distal to the narrowing (supplying lower body) depends on a patent ductus arteriosus, and hence its closure can be life-threatening.
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Postductal type Most common. The narrowing is distal to the ductus
arteriosus. The ductus usually remains open to
communicate pulmonary artery with the descending aorta
Even with an open ductus arteriosus blood flow to the lower body can be impaired.
Allows development of collateral circulation during the fetal period. The collateral circulation will develop mainly by branches from both subdavian arteries, scapular, internal thoracic and intercostal arteries.
It is associated with notching of the ribs, hypertension in the upper extremities, and weak pulses in the lower extremities.
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Right Arch of Aorta Occurs when the entire right aortic arch persists &the segment of left dorsal aorta distal to the 7th intersegmental artery involutes
TYPES: Without retropharyngeal component: The DA passes from right pulmonary artery to right arch of aorta. No effect on the trachea & esophagus
With retropharyngeal component: The right arch lies posterior to esophagus. The attachment of DA to distal part of the arch of aorta forms a ring around the trachea & esophagus and may lead to their compression
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Double Arch of Aorta Characterized by a vascular
ring encircling the trachea and esophagus, usually causing compression of both structures.
The degree of compression varies
Usually the right arch is larger and passes posterior to the esophagus
The right common carotid and subclavian arteries arise separately from right arch
RSA LSA
LCCRCC
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Patent Ductus Arteriosus Before birth, the aorta and
the pulmonary artery are normally connected by a blood vessel called the ductus arteriosus, which is an essential part of the fetal circulation.
After birth, the vessel is supposed to close within a few days. The obliterated vessel forms the ligamentum arteriosum.
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In some babies, the ductus arteriosus remains open (patent).
This allows blood to flow directly from the aorta into the pulmonary artery, which can put a strain on the heart and increase pressure in the pulmonary circulation
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Abnormal Right Subclavian Artery
May arise from the distal part of arch of aorta
In some cases, the right subclavian artery arises from the descending aorta and runs behind the trachea and the esophagus to supply the right upper limb
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Thank You
&
Good Luck