THE ADDICTIVE BRAIN

SC 212 JANUARY 10 2017

JOHN BUSH

OVERVIEW • Lecture One: Addiction 101 • Lecture Two: The Reward System • Lecture Three: Addiction Hijacks the the Brain • Lecture Four: Genetics and addiction • Lecture Five: How do drugs of abuse work? • Lecture Six: Coffee and Cigarettes • Lecture Seven: Alcohol • Lecture Eight: Marijuana • Lecture Nine: Stimulants- Cocaine, Amphetamines • Lecture Ten: Opioids • Lecture Eleven: Behavioral Addictions-Gambling Disorder • Lecture Twelve: Behavioral Addictions(?)-Supernormal Stimuli

NEURAL MECHANISMS OF REWARD PROCESSING-THE REWARD CIRCUIT

• Nucleus accumbens(Nac)—the pleasure center

• Ventral tegmental area(VTA)—the learning function

• Prefrontal cortex(PFC)—the executive function

DOPAMINERGIC PATHWAYS

NUCLEUS ACCUMBENS

DOPAMINE/SEROTONIN PATHWAYS

REPEAT OF THE CONCLUSION OF DVD LECTURE THREE

DVD LECTURE FOUR GENETICS—BORN TO BE AN ADDICT?

SUMMARY: GENETICS OF ADDICTION

• Nearly all aspects of addiction can be influenced by genetics

• There is no single “addiction gene” • The same genes are involved in different

addictions • The existence of an “addictive personality” is

plausible • There is some progress toward establishing the

ways that specific genes affect addiction

BREAK

DVD LECTURE FIVE YOUR BRAIN ON DRUGS

KIDS HAVE QUESTIONS WALL STREET JOURNAL

12/29/2016

DVD LECTURE SIX

WHY WE CRAVE COFFEE AND CIGARETTES