TAYLOR ARLEDGE, NNEOMA OBIESHI, ANGELINA BAJRA

Hemophilia

What is Hemophilia? Hemophilia is an X linked recessive blood disease

Most common in Caucasian men, as most x liked genetic disorders

Results from a deficiency in the clotting factor Often called Christmas Disease or the Disease of the Royals

Hemophilia A and Hemophilia B Hemophilia A would be the most common out of the two

due to the decreased activity of factor VIII which aids in clotting

Hemophilia B is much like Hemophilia A except the deficiency involves Factor IX Known as Christmas Disease

How is Hemophilia inherited?

How the disorder is inherited? Through a carrier Mother or a Hemophiliac Father

(paired with normal mates or combined

Can someone be a carrier for Hemophilia Women are always the carriers of this disease

Women have two x chromosomes and can only he hemophiliacs if they hare homozygous for the recessive trait

Inheritance patterns

Symptoms includeSymptoms include How the disease is diagnosedHow the disease is diagnosed

Excessive bleeding Bleeding in the joints Joint scarring Bruises Hemorrhage

Demographics “Hemophilia A affects

between one in 5,000 to one in 10,000 males in most populations.”(Gale)

Genetic testing Amniocentesis DNA

testing of fetal cells shed into the amniotic fluid for genetic mutations.

chorionic villus sampling examines proteins for the defects that lead to hemophilia. (gale)

Symptoms & Diagnosis

Treatment and Cures

Treatment Usually the patient is injected with the deficient factor

Hemophiliacs A receiving Factor VIII Hemophiliacs B receiving Factory IX

Other simpler modes of handling this disorder are wearing protective clothing on bodily areas that go through much contact as in the hands feet or arms.

Effectiveness of Treatmnent the treatment is used in emergency settings only and

not daily administered. Works when needed.

Works Cited

Wilson, Jennifer F. "Hemophilia." Gale Virtual Reference Library. Ed. Brigham Narins. Vol.1 and 2 ed. N.p., 2006. Web. 7 Feb. 2011. <http://go.galegroup.com/ps/ i.do?&id=GALE

%7CCX3451500193&v=2.1&u=s0351&it=r&p=GVRL&sw=w

"What Is Hemophilia, Hemophilia A, and Hemophilia B?" National Heart, Lung and Blood Institute. July 2009. Web. 07 Feb. 2011. <http://www.nhlbi.nih.gov/health/dci/Diseases/hemophilia/hemophilia_what.html>.

Raabe, Michelle, Ph.D. Hemophilia. New York City: Chelsea House, 2008. Print

Pacheco, Maria. "Hemophilia." Magill's Medical Guide. Ed. Dann P. Dawson. Vol. 3.      Pasadena, California: Salem Press Inc., 2008. 1282-1285. Print.

“Hemophilia." Human Diseases and Conditions. Ed. Niel Tzenburg, M.D. New york,      New York: Charles Scribner's and Sons, 2000. 434-438. Print.