table 1.1.1: stock and flow of blood and marrow transplantation, 1987-2005

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Table 1.1.1: Stock and Flow of Blood and Marrow Transplantation, 1987-2005. *1 patient in year transplant 2001 with no death date **2 patients with missing outcome status and 1 patient with unknown outcome status - PowerPoint PPT Presentation

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  • Table 1.1.1: Stock and Flow of Blood and Marrow Transplantation, 1987-2005 *1 patient in year transplant 2001 with no death date**2 patients with missing outcome status and 1 patient with unknown outcome status*Out of 1048 patients who were transplanted, there were 40 patients with early death before day 30 of transplant

    Year878889909192939495New transplant patients862251221192530Deaths1166129516Lost to follow up000000000Alive at 31st December712282738576787101

    Year969798990001*02030405New transplant patients2833496294108114128139145Deaths11151715314730504339Lost to follow up0000000000Alive at 31st December118136168215278338422500596699**

  • Figure 1.1.1: Stock and Flow of Blood and Marrow Transplantation, 1987-2005 Number of patientsYear0100200300400500600700 New patients Alive at 31st Dec1987198819891990199119921993199419951996199719981999200020012002200320042005

  • Table 1.1.2: New Transplant Rate per million population (pmp), 1987-2005Figure 1.1.2: New Transplant Rate per million population (pmp), 1987-2005

    Year198719881989199019911992199319941995New transplant patients862251221192530New transplant rate pmp 001011111

    Year1996199719981999200020012002200320042005New transplant patients2833496294107114128139145New transplant rate pmp 1223445556

  • Table 1.1.3: Centre distribution (SDP), 1987-2005

    Year1987198819891990199119921993No.%No.%No.%No.%No.%No.%No.%KLA00000000000000KLP00000000000000UKM00000000000000SJA00000000000000UMA00000000000015UMP8100610022100510012100211001895GMC00000000000000LWE00000000000000SJP00000000000000TOTAL81006100221005100121002110019100

    Year1994199519961997199819992000No.%No.%No.%No.%No.%No.%No.%KLA00000000006101516KLP41610331139927163319311415UKM000000000023910SJA0000000000581920UMA416723621927153111181314UMP1768134311391545183719312426GMC00000000000000LWE00000000000000SJP00000000000000TOTAL25100301002810033100491006210094100

  • Table 1.1.3: Centre distribution (SDP), 1987-2005

  • Figure 1.1.3: Centre distribution (SDP), 1987-2005NumberYear0102030405060708090100110120 KLA KLP UKM SJA UMA UMP1987198919911993199519971999200120032005

  • Table 1.2.1: Gender distribution, 1987-2005

    Year19871988198919901991199219931994GenderNo.%No.%No.%No.%No.%No.%No.%No.%Male7884671255360758136213681664Female1132331045240542838632936TOTAL8100610022100510012100211001910025100

    Year19951996199719981999200020012002GenderNo.%No.%No.%No.%No.%No.%No.%No.%Male11371554185533673658545766616254Female19631346154516332642404342395246TOTAL301002810033100491006210094100108100114100

    Year200320042005TOTALGenderNo.%No.%No.%No.%Male71558360694859357Female57455640765245543TOTAL1281001391001451001048100

  • Figure 1.2.1: Gender distribution, 1987-2005 PercentYear020406080100 Male Female1987198919911993199519971999200120032005

  • Table 1.2.2: Ethnic group distribution, 1987-2005

    Year1987198819891990199119921993RaceNo.%No.%No.%No.%No.%No.%No.%Malay2254671359240433419316Chinese56323383636075810481053Indian1130000001841915Bumiputra Sabah0000150000210316Bumiputra Sarawak000000000000211Others00000000001500TOTAL81006100221005100121002110019100

    Year1994199519961997199819992000RaceNo.%No.%No.%No.%No.%No.%No.%Malay936723829927204131503335Chinese1248144711392061244926424851Indian0031062100484677Bumiputra Sabah416130013000033Bumiputra Sarawak000031100000000Others005170039121233TOTAL25100301002810033100491006210094100

  • Table 1.2.2: Ethnic group distribution, 1987-2005

  • Figure 1.2.2: Ethnic group distribution, 1987-2005 PercentYear0102030405060708090100 Malay Chinese Indian Bumiputra Sarawak1987198919911993199519971999200120032005 OthersBumiputra Sabah

  • Table 1.2.3: Age distribution, 1987-2005

    Year1987198819891990199119921993Age groupNo.%No.%No.%No.%No.%No.%No.%0-9450467177751001083157194710-1945023352300217629105320-390000000000000040-5900000000000000>=6000000000000000TOTAL81006100221005100121002110019100Mean9786679SD4333445Median98866610Minimum2212111Maximum1510139131417

    Year1994199519961997199819992000Age groupNo.%No.%.No.%No.%No.%No.%No.%0-9114412401346195821432845272910-1911441343124382416331524272920-3931241331151512241219192040-5900130013007112021>=6000000000000011TOTAL25100301002810033100491006210094100Mean 11131112131723SD79912101517Median1111116101118Minimum13115 months11Maximum29413745395761

  • Table 1.2.3: Age distribution, 1987-2005*Age=date of transplant date of birth

    Year20012002200320042005TOTALAge groupNo.%No.%No.%No.%No.%No.%0-9232130264233261929203453310-19282625221814412930212732620-39403736324737523750342832740-591615232021161813352414214>=60110000211150TOTAL1081001141001281001391001451001048100Mean232322232619SD161615151615Median222223202514Minimum1 month15 months111 monthMaximum645552706670

  • Figure 1.2.3: Age distribution, 1987-2005

  • Table 1.2.4: Primary Diagnosis, 1987-2005

    Year1994199519961997199819992000DiagnosisNo.%No.%No.%No.%No.%No.%No.%Acute leukaemia832103313463739113323472845Chronic leukaemia4165175181314618714711Hypoplastic anaemia52082741411125154858Erythrocytic disorders00001400000000Lymphoma000000192026510610Solid tumors14130022132458Myelodysplasia28000011001200Haemoglobinopathy520517518776182446Multiple myeloma00000011000035Others001300332651046TOTAL25100301002810094100331004910062100

  • Table 1.2.4: Primary Diagnosis, 1987-2005

  • Table 1.2.4: Primary Diagnosis, 1987-2005

  • Table 1.3.1: Graft number, 1987-2005

    Year1987198819891990199119921993Graft numberNo.%No.%No.%No.%No.%No.%No.%181006100198648097519901895200002912032521015300001500000000TOTAL81006100221005100121002110019100

    Year1994199519961997199819992000Graft numberNo.%No.%No.%No.%No.%No.%No.%124962997281003194489861989197214130013121233300000013000000TOTAL25100301002810033100491006210094100

    Year20012002200320042005TOTALGraft numberNo.%No.%No.%No.%No.%No.%1103951139912598134981149898497255113232223133000000000020TOTAL1081001141001281001371001161001017100

  • Figure 1.3.1: Graft number, 1987-2005PercentYear020406080100 Graft number 1 Graft number 2 Graft number 31987198919911993199519971999200120032005

  • Table 1.3.2: Type of transplant, 1987-2005*6 patients with syngeneic type of transplant

    Year198719881989199019911992Type of transplantNo.%No.%No.%No.%No.%No.%Allogeneic + Syngeneic8100610021955100121002095Autologous000015000015TOTAL810061002210051001210021100

    Year1993199419951996199719981999Type of transplantNo.%No.%No.%No.%No.%No.%No.%Allogeneic + Syngeneic1895249629972693278232654471Autologous1514132761817351829TOTAL19100251003010028100331004910062100

    Year200020012002200320042005TOTALType of transplantNo.%No.%No.%No.%No.%No.%No.%Allogeneic + Syngeneic56607569756684669065886174071Autologous38403331393444344935563930729TOTAL941001081001141001281001391001441001047100

  • Figure 1.3.2: Type of transplant, 1987-2005

  • Table 1.3.3: Type of transplant by Centre, 1987-2005

  • Figure 1.3.3: Type of transplant by Centre, 1987-2005

  • Table 1.3.4: Transplant source, 1987-2005

    Year19871988198919901991Transplant sourceNo.%No.%No.%No.%No.%Marrow8100610022100510012100PBSC / Marrow + PBSC0000000000Cord blood / Marrow + cord 0000000000TOTAL8100610022100510012100

    Year19921993199419951996Transplant sourceNo.%No.%No.%No.%No.%Marrow2110019100251003010028100PBSC / Marrow + PBSC0000000000Cord blood / Marrow + cord 0000000000TOTAL2110019100251003010028100

    Year19971998199920002001Transplant sourceNo.%No.%No.%No.%No.%Marrow24732551302837603133PBSC / Marrow + PBSC7212347746923375761Cord blood / Marrow + cord 2612442366TOTAL33100491001081006210094100

    Year2002200320042005TOTALTransplant sourceNo.%No.%No.%No.%No.%Marrow312744343022231645143PBSC / Marrow + PBSC79697962100721157955753Cord blood / Marrow + cord 44549675404TOTAL1141001281001391001451001048100

  • Figure 1.3.4: Transplant source, 1987-2005Number020406080100120140 Marrow PBSC/ Marrow+ PBSC Cord blood/ Marrow + cord1987198919911993199519971999200120032005Year

  • Table 1.3.5: HLA Match, 1987-2005 *excluding autologous

    Year19871988198919901991HLA MatchNo.%No.%No.%No.%No.%Identical81006100211005100121001 AG00000000002 AG0000000000>=3 AG Disparate0000000000TOTAL8100610021100510012100

    Year19921993199419951996HLA MatchNo.%No.%No.%No.%No.%Identical2010023962910026100181001 AG00140000002 AG0000000000>=3 AG Disparate0000000000TOTAL2010024100291002610018100

  • Table 1.3.6: Allogeneic Donor Relationship, 1987-2005*excluding autologous, including syngeneic

    Year19871988198919901991Allogeneic Donor RelationshipNo.%No.%No.%No.%No.%Sibling810061002110051001192Unrelated0000000000Others0000000018TOTAL8100610021100510012100

    Year19921993199419951996Allogeneic Donor RelationshipNo.%No.%No.%No.%No.%Sibling201001810022922910026100Unrelated0000000000Others0000280000TOTAL2010018100241002910026100

    Year19971998199920002001Allogeneic Donor RelationshipNo.%No.%No.%No.%No.%Sibling2696321007296441005598Unrelated1400340012Others0000000000TOTAL2710032100751004410056100

    Year2002200320042005TOTALAllogeneic Donor RelationshipNo.%No.%No.%No.%No.%Sibling719581968190799170796Unrelated453491089294Others0000000030TOTAL75100841009010087100739100

  • Table 1.4.1: Cause of Death, 1987-2005

    Year19871988198919901991Cause of deathNo.%No.%No.%No.%No.%Sepsis11000000001100GVHD00000011700Underlying disease0000610058300Haemorrhage001100000000VOD0000000000Organ Failure0000000000Interstitial pneumonitis0000000000Secondary malignancy0000000000Others0000000000Unknown0000000000TOTAL11001100610061001100

    Year19921993199419951996Cause of deathNo.%No.%No.%No.%No.%Sepsis150222120425655GVHD00000042500Underlying disease006673

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