surface moulds for the hdr microselectron afterloader ......“a century of x-rays and radioactivity...

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The Christie NHS Foundation Trust Surface Moulds for the HDR MicroSelectron Afterloader Mould Room Techniques Part One: The Past, the Present & Future Tony Stanton Mould Room Manager The Christie Foundation NHS Trust

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Page 1: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Surface Moulds for the HDR MicroSelectron Afterloader Mould Room Techniques

Part One: The Past, the Present & Future

Tony Stanton Mould Room Manager

The Christie Foundation NHS Trust

Page 2: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Synopsis

• The evolution of moulds from live source to afterloaded moulds progressing to current Scan & Plan technique using the Freiburg Flap

Page 3: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

1905 Photograph showing the method of strapping on

small tubes of radium to the skin to treat malignancies.

Transferred from en.wikipedia (Original text : Metzenbaum, Myron (1905). "Radium: Its value in the treatment of lupus, rodent ulcer, and epithelioma, with reports of cases". International clinics (J.B. Lippincott) 4:14: 21-31.)

Page 4: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

1922–1923 at the Institut Curie, Paris

a) Patient before radium treatment, March 1922. b) Patient with radium applicator in the treatment position, February 1923. c) Patient follow-up later in 1923. Br J Radiol. 1998 Dec;71(852):1229-54. The discovery of radium in 1898 by Maria Sklodowska-Curie (1867-1934) and Pierre Curie (1859-1906) with commentary on their life

and times. Mould RF.

Page 5: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

R. F. Mould “A Century of X-Rays and

Radioactivity in Medicine: With Emphasis on Photographic Records of the

Early Years” (1993)

Page 6: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Birth of the Mould Room

• This is where we came from

• Radium first used in the 1900’s

(first used in Manchester 1903)

• Moulds followed very quickly after that

• Mould rooms well established by 1920’s

Page 7: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Page 8: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Brachytherapy Moulds at Christie • Moulds well established pre 1930’s • Ralston Paterson visited Brussels 1932 returning

with ideas for improvements • 1937 “The Construction of Superficial Applicators for Radium Therapy “

Paterson & McVicar British Journal Of Radiology Very detailed description of techniques

• Radium / Cobalt60 Moulds continued until 1991 • 1991 MicroSelectron Afterloaded moulds • 2013 Freiburg Flap introduced

Page 9: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Traditional Live Mould (Co60)

Page 10: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Page 11: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Live Radium / Cobalt Moulds

• Long treatment times up to 8hrs per day / 8days • Patient comfort issues • Mould application and cleaning

• Radiation safety- Staff / other patients

Source security

Most of these issues solved by afterloading technique

Page 12: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

HDR Microselectron Mould Advantages

• Afterloaded: No radiation hazard whilst fitting

or servicing the mould. eg cleaning • Short treatment time means patient comfort

considerations in mould design less important. This may allow patient to tolerate more severe positioning

• Smaller source size allows tricky source placements

Page 13: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Page 14: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Page 15: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Page 16: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Treatment height, d

Mould thickness

Drilled post height / Platform height

Combined Source/catheter diameter 2.00mm

Traditional Mould – Treatment Height

Height and position of sources was critical

Page 17: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Page 18: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

• Traditionally Paterson-Parker rules • Moulds often scanned and planned allowing

some variation in source dwell times

……but very little other flexibility in planning and treatment delivery!

Page 19: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Manchester Paterson-Parker system • Traditional moulds impose fixed geometry as

source position is fixed • Mould accuracy was crucial as treating distance

determined dose • Little progression from historical moulds • Not taking advantage of available technology

scanning, planning, treatment delivery systems

• Pre-fixed array arrangement would allow more

flexible planning approach

Page 20: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Treatment Sites

• Finger, Hand, Wrist, Forearm • Leg • Scalp • Pinna

Page 21: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Freiberg Flap

• Aquaplast Custom Bolus used as spacer material over foundation shell

• Flexible Catheter array fixed to mould using nylon M4 bolts

Page 22: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

Surface Moulds …….The Future

• Further developmentof useage of Thermoplastic

material (pros & cons) • Speed up adhesives method.

Glue gun/ thermo setting adhesives

• 3D Printing is being explored elsewhere

Page 23: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

3D Printed Patient-specific Surface Mould Applicators for Brachytherapy Treatment of Superficial Lesions

Ian Cumming et al

Laboratory for Percutaneous Surgery, School of Computing, Queen's University, Kingston,Ontario, Canada CCSEO, Kingston General Hospital and Department of Oncology, Queen's University,Kingston, Ontario,

Canada http://perk.cs.queensu.ca/sites/perkd7.cs.queensu.ca/files/Cumming2014.pdf

Page 24: Surface Moulds for the HDR MicroSelectron Afterloader ......“A Century of X-Rays and Radioactivity in . Medicine: With Emphasis on Photographic Records of the Early Years” (1993)

The Christie NHS Foundation Trust

To Be Continued…… Part Two

Practical aspects of Skin Surface Moulds