subject index

Subjcet Index Acid phosphatase activity 7-9. II. 12.31 - classification 7 - effects of fixation 9 - in bone 8, 9, II, 12 - in cartilage 8. 9, II, 12 - in skeletal diseases 3I Alkaline phosphatase 7-10,12.14,15,17,18.21.22, 24. 26- 28 .32 - classification 7 - effects of fixation 10 - in bone 9.12,14.15,17,18,21 - in cartilage 8-10. 22, 24. 26, 27 - in skeletal diseases 9,28. 32 Aryl sulfatase 7. II. 16. 18.20,22,34 - classification 7, II - lysosomal reaction II, 16.20.22,34 - Golgi reaction 18, 20 ATPase 8 Azo dye methods 9. 22 Agranular endoplasmic reticulum 18. 20 Articular cartilage 22 - lysosomal reaction 22. 25 Bone matrix 2. 21, 22 - degradation by enzymes 2 I. 22 Blood vessels 26, 27 Cartilage cells 3.5,6,9. 10,22,24.26,27 - resting or reserve 3, 24. 25 - proliferating 5 - maturing 5 - hypertrophied 5,9. 22 - degenerating 6, 22 - enzyme activity 9, 10.22.24-26.27 Cathepsin D 8 Cell surface 12. 14, 17.24-29,34 - alkaline phosphatase activity 12, 14. 17.29 - cartilage 24-29,34 Collagen 5, 27. 30 Endosteal cells 27 Endothelial cells 27, 29 Esterase 9 Fixation 10. II - effect on enzyme activity 10 [3-Galactosidase 8. 9 - in bone 8 - in cartilage 9 Giant cells 28,31-33.35 - in osteosarcoma 28, 3I. 32, 35 - in giant cell tumor (osteoclastoma) 3I, 33. 35 - foreign body giant cells 32, 35 9, 10 - effects of fixation 10 - in cartilage 9 n-Acetyl in cartilage 9 Golgi apparatus 12-15. 18-20,24 - phosphatase activity in osteoblasts 12-14 -- in osteocytes 15 - - in osteoclasts 18-20 - sulfatase activity 20 - phosphatase activity in cartilage cells 24 Histochemical methods 10, II. 22 Inclusion bodies 3, 27. 30. 32. 34 Inhibitors of enzyme activity I I, 34 Lysosomes - enzyme activity in bone cells 8. 9,12.13.15-22, 24-34 -- in cartilage 8-12. 22. 24-27, 32. 34.35 -- in endothelial cells 29 -- in fibroblasts 27. 30 Matrix vesicles 9. 10. 26, 29 Mitochondria 18. 33 Mucolipidosis III 32, 35 Neutral phosphatase 9-17,21,24,26.32.34.35 - cell membrane 12-14,15,17,24 - in lysosomes 9, II. 12,15-17,21,24,26.32.34,35 Osteoblasts 2, 9.12-15,17 Osteoclast 3-5,12,17-22.24,27,32.34 Osteocyte 3.12,15,16,34 Osteogenesis impcrfecta tarda 9, 28. 31. 35 Osteosarcoma 28, 3I. 32 35 Periosteum 27, 30 Phosphamidase 7. 9, II-13. 24, 34 Phosphoprotein phosphatase 7, 8 Pseudoachondroplasia 32, 34. 35 Ruffled border 3-5. 12.21,22.34 Trimetaphosphatase 7. 9, I 1,12,18.19.24.34 Vacuoles 3. 4, 21, 32, 35

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Subjcet Index

Acid phosphatase activity 7-9. II. 12.31- classification 7- effects of fixation 9- in bone 8, 9, II, 12- in cartilage 8. 9, II, 12- in skeletal diseases 3I

Alkaline phosphatase 7-10,12.14,15,17,18.21.22,24. 26- 28.32

- classification 7- effects of fixation 10- in bone 9.12,14.15,17,18,21- in cartilage 8-10. 22, 24. 26, 27- in skeletal diseases 9,28. 32Aryl sulfatase 7. II. 16. 18.20,22,34- classification 7, II- lysosomal reaction II, 16.20.22,34- Golgi reaction 18, 20ATPase 8Azo dye methods 9. 22Agranular endoplasmic reticulum 18. 20Articular cartilage 22- lysosomal reaction 22. 25

Bone matrix 2. 21, 22- degradation by enzymes 2I. 22Blood vessels 26, 27

Cartilage cells 3.5,6,9. 10,22,24.26,27- resting or reserve 3, 24. 25- proliferating 5- maturing 5- hypertrophied 5,9. 22- degenerating 6, 22- enzyme activity 9, 10.22.24-26.27Cathepsin D 8Cell surface 12. 14, 17.24-29,34- alkaline phosphatase activity 12, 14. 17.29- cartilage 24-29,34Collagen 5, 27. 30

Endosteal cells 27Endothelial cells 27, 29Esterase 9

Fixation 10. II- effect on enzyme activity 10

[3-Galactosidase 8. 9- in bone 8- in cartilage 9

Giant cells 28,31-33.35- in osteosarcoma 28, 3I. 32, 35- in giant cell tumor (osteoclastoma) 3I, 33. 35- foreign body giant cells 32, 35~-Glucuronidase 9, 10- effects of fixation 10- in cartilage 9n-Acetyl ~-glucosaminidasein cartilage 9Golgi apparatus 12-15. 18-20,24- phosphatase activity in osteoblasts 12-14- - in osteocytes 15- - in osteoclasts 18-20- sulfatase activity 20- phosphatase activity in cartilage cells 24

Histochemical methods 10, II. 22

Inclusion bodies 3, 27. 30. 32. 34Inhibitors of enzyme activity I I, 34

Lysosomes- enzyme activity in bone cells 8. 9,12.13.15-22,

24-34- - in cartilage 8-12. 22. 24-27, 32. 34.35- - in endothelial cells 29- - in fibroblasts 27. 30

Matrix vesicles 9. 10. 26, 29Mitochondria 18. 33Mucolipidosis III 32, 35

Neutral phosphatase 9-17,21,24,26.32.34.35- cell membrane 12-14,15,17,24- in lysosomes 9, II. 12,15-17,21,24,26.32.34,35

Osteoblasts 2, 9.12-15,17Osteoclast 3-5,12,17-22.24,27,32.34Osteocyte 3.12,15,16,34Osteogenesis impcrfecta tarda 9, 28. 31. 35Osteosarcoma 28, 3I. 32 35

Periosteum 27, 30Phosphamidase 7. 9, II-13. 24, 34Phosphoprotein phosphatase 7, 8Pseudoachondroplasia 32, 34. 35

Ruffled border 3-5. 12.21,22.34

Trimetaphosphatase 7. 9, I 1,12,18.19.24.34

Vacuoles 3. 4, 21, 32, 35

19. Alphabetical Subject Index

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