Study Eligibility Criteria: Interactive Study Eligibility Criteria: Interactive QuizQuiz

Melissa McPheeters, PhD, MPH Melissa McPheeters, PhD, MPH Associate Director, Associate Director,

Vanderbilt University Evidence-based Practice Vanderbilt University Evidence-based Practice CenterCenter

Interactive Quiz: InstructionsInteractive Quiz: Instructions

Open this presentation as a slideshow. This will activate the hyperlinks.

When you come to a question, choose the red box corresponding to your choice. If you are correct, you will be directed forward. If you are incorrect, you will be directed back to the question to choose again.– Click on forward hyperlinks (Red Boxes) to follow

through based on your responses.

– Click on home hyperlink (Blue House Icon) to go back to the last correct step in the series.

Participation Quiz: Participation Quiz: Question 1Question 1

When selecting study criteria, it is important to keep the PICOTS principles in mind. What does PICOTS stand?

Personal, Interest, Comparison, Observation, Time, and Situation

Population, Intervention, Comparators, Outcomes, Timing, and Setting

Public, Individual, Community, Organization, Time, and Society

None of the above

Correct!Correct!

PopulationPopulation—condition, disease severity and —condition, disease severity and stage, comorbidities, patient demographicsstage, comorbidities, patient demographics

InterventionIntervention—dosage, frequency, and method —dosage, frequency, and method of administrationof administration

ComparatorsComparators—placebo, usual care, or active —placebo, usual care, or active controlcontrol

OutcomesOutcomes—health outcomes, morbidity, —health outcomes, morbidity, mortality, quality of life (QoL)mortality, quality of life (QoL)

TimingTiming—duration of follow-up—duration of follow-up SettingSetting—primary, specialty, in-patient, —primary, specialty, in-patient,

cointerventionscointerventions

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Not quite. PICOTS will include the important global ideas applicable to all phases of your review.

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Participation Quiz: Question 2

N > 30 could be an example of study selection criteria.

True

False

Correct!Correct!

Other examples can include– Adult, community-dwelling females

– Study of a screening tool for depression

– United States only

– Hospital-based studies only

– N > 200

– Randomized controlled trials

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Selection criteria are the rules that dictate whether a study will be included or excluded.

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Participation Quiz: Participation Quiz: Question 3Question 3

Study selection criteria should be determined after the abstract review process is underway.

True

False

Correct!Correct!

Selection criteria should be determined prior to any literature investigation to reduce bias. When determining selection criteria, it is important to– Review study goals

– Assess analytic framework and key questions

– Tie criteria to PICOTS

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Determining selection criteria after reviewing literature may introduce bias and skew the results.

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Participation Quiz: Participation Quiz: Question 4Question 4

Using well-constructed selection criteria can help avoid which of the following?

Too much literature to feasibly review, or disparate literature that cannot be compared

Too little literature

Inability to answer the intended question

All of the above

Correct!Correct!

Selection criteria are powerful tools for broadening or narrowing the scope of a review. When properly constructed and applied, selection criteria will reduce bias and enhance the applicability of the review.

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That choice is correct, but what’s wrong with the other ones?

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Congratulations!Congratulations!

You have successfully completed the quiz!

Determining selection criteria is one of the most integral steps to any review. A thorough understanding of the topic material and aims of the review is necessary when setting these criteria.

If you have any questions, please refer to the slide set for Module 3.