silvia s. martins, md, phd up to 2010...silvia s. martins, md, phd curriculum vitae (10/2009) silvia...

Silvia S. Martins, MD, PhD

CURRICULUM VITAE (10/2009)

SILVIA S. MARTINS, M.D., P.H.D

PERSONAL DATA

Johns Hopkins Bloomberg School of Public Health

624 North Broadway. 8th floor, suite 896 Baltimore MD 21205 E-mail: [email protected] Phone: 410-614-2852 Fax: 410-955-9088

EDUCATION AND TRAINING

Period Degree/Program Institution Field of Study 1992 – 1998 M.D. Federal University of Paraná, Brazil Medicine 1998 –1999 Residency University of São Paulo (1st year only) Medical School- Ribeirão Preto unit Pediatrics

Department of Pediatrics, Brazil 1999 – 2001 Residency University of São Paulo

Medical School Psychiatry Department of Psychiatry, Brazil

2001 – 2003 Ph.D. University of São Paulo

Medical School Psychiatry Department of Psychiatry, Brazil (Addiction)

2003 - 2005 Post-Doctoral Department of Mental Health Drug Abuse Fellow Johns Hopkins Bloomberg Epidemiology

School of Public Health

PROFESSIONAL EXPERIENCE

2009-present Associate Department of Mental Health Scientist Johns Hopkins Bloomberg

School of Public Health My principal responsibilities include: working as a Principa lInvestigator in three different NIH funded research projects and as a Co-Investigator on a fourth research project, preparation of research grant proposals, large survey data analysis and supervision of data analysis and data collection conducted by Research Assistants, preparation of research manuscripts for peer-reviewed publications and scientific meetings. I am also a Special Studies advisor (1st term 2009-2010) for a PhD candidate in my department, I am the mentor of an MHS student (2009-2010). 2007-2009 Assistant Department of Mental Health Scientist Johns Hopkins Bloomberg


School of Public Health My principal responsibilities include: preparation of research grant proposals, large survey data analysis and supervision of data analysis and data collection conducted by Research Assistants, preparation of research manuscripts for peer-reviewed publications and scientific meetings. I am also a Special Studies advisor (4th term 2007-2008, 2nd and 3rd terms 2008-2009) for a PhD candidate in my department, I am the mentor of an MHS student (2008-2009) and I am in the Thesis Advisory and Final Defense Committee of an HBS PhD candidate and of a Mental Health PhD candidate. 2005- 2007 Research Department of Mental Health Associate Johns Hopkins Bloomberg

School of Public Health My principal responsibilities included: preparation of research grant proposals, large survey data analysis and supervision of data analysis conducted by Research Assistants, preparation of research manuscripts for peer-reviewed publications and scientific meetings. 2003 - 2005 Post-Doctoral Department of Mental Health Drug Abuse Fellow Johns Hopkins Bloomberg Epidemiology

School of Public Health My principal responsibilities included: preparation of research grant proposals, large survey data analysis and supervision of data analysis conducted by Research Assistant, preparation of research manuscripts for peer-reviewed publications and scientific meetings. I attended courses on Psychosocial Methods for Research, Longitudinal Data Analysis and Survival Analysis, and on Drug Abuse Epidemiology during my post-doctoral training at JHSPH. 2001 – 2003 Clinical University of São Paulo

Psychiatrist Medical School Gambling Outpatient Unit (part-time) Department of Psychiatry, Brazil

My principal responsibilities included: preparation of research grant proposals, data collection, data analysis, data entry, supervision of medical residents and psychology students, preparation of research manuscripts for peer-reviewed publications and scientific meetings. I also had clinical responsibilities that included patient interviewing for research purposes, and patient clinical and psychotherapy treatment.

2001-2003 Private practice as psychiatrist (part-time)

PROFESSIONAL ACTIVITIES

Society Membership and Leadership

Brazilian Medical Council Brazilian Psychiatric Association Associate Member - The College on Problems of Drug Dependence Member - American Public Health Association Member - American Public Health Association Latino Caucus American Public Health Association Latino Caucus Scientific Program Co-Chair for the 2006 APHA Annual Meeting


Member- The College on Problems of Drug Dependence Under-represented Minority Committee- 2008-2010 Member- Board of Directors, Maryland Coalition on Problem Gambling Member, National Council on Problem Gambling Regular Member, World Psychiatric Association Epidemiology and Public Health Section Member, American Psychopathological Association

EDITORIAL ACTIVITIES

Peer Review Activities

Journal of Clinical Psychiatry - 2004 - present Elsevier books - 2005 - present American Journal on Addictions - 2006 - present Drug and Alcohol Dependence - 2005 - present American Journal of Public Health - 2006 - present Revista Brasileira de Psiquiatria (Brazilian Psychiatric Journal) - 2006 - present Alcoholism: Clinical & Experimental Research - 2007-present European Child & Adolescent Psychiatry - 2007-present Pharmacoepidemiology and Drug Safety - 2007- present (recognized as “outstanding reviewer” by the journal in 2007) Psychology of Addictive Behaviors - 2008-present Journal of Nervous and Mental Diseases- 2008- present BMC Public Health-2008-present Addiction- 2008-present CNS Spectrums- 2008-present Neuropsychobiology- 2008- present Psychiatry Research- 2009- present Editorial Board Membership The Open Neuropsychopharmacology Journal -2008- present The Open Addiction Journal- 2009- present Associate Editor- BMC Public Health- 2009- present

Ad Hoc Review of Proposals

Proposal review (10/2005): The Netherlands Organization for Health Research and Development (ZonMw, The Hague). Proposal Review (10/2007), NIH-NCCAM’s (National Center for Complementary and Alternative Medicine) Special Emphasis Panel ZAT1-JH24 Proposal Review (12/2007), NIH- NIDA’s (National Institute on Drug Abuse) Special Emphasis Panel/Scientific Review Groups 2008/01 ZDA1 MXS-M (13) & 2008/05 ZDA1 MXS-M (05), acted as Chairperson. Proposal Review (05/2009) NIH-NIDA’s (National Institute on Drug Abuse) Special Emphasis Panel/Scientific Review Groups for Phase I Review of Challenge Grants ZRG1 PSE-J 58 R & ZRG1 PSE-C 58 R.

HONORS AND AWARDS

Honors

Pre-Doctoral Research Scholarship, São Paulo Research Council (FAPESP), Brazil


Postdoctoral Overseas Research Scholarship, National Council of Research (CNPq- Brazil) CNPq 20.018/2004-0 from 08/01/04 – 07/31/05

Elected Associate Member, The College on Problems of Drug Dependence, August 01 2006.

Elected Regular Member, The College on Problems of Drug Dependence, August 01 2009.

Awards

American Psychiatric Association Research Colloquium for Junior Investigators Award May 2, 2004, New York, New York Incentive grant for Young investigators Award- Institute for Research on Pathological gambling and related disorders, Division on Addictions, Harvard Medical School, 2004-2005 1RO3 DA020923-01 Martins (PI) 09/30/05 – 06/30/08 PREDICTORS OF ADOLESCENT ECSTASY USE IN THE NATIONAL SURVEY OF PARENTS AND YOUTH American Psychiatric Association Research Colloquium for Junior Investigators Award May 21, 2006, Toronto, Canada 1 Ontario Problem Gambling Research Centre grant Martins (PI) 03/31/07- 03/30/08 SUBTYPING GAMBLING BEHAVIORS IN THE CANADIAN GENERAL POPULATION 1 R21 DA020667-01A2 Martins (PI) 05/15/07– 04/30/09 TRENDS IN PROBLEMS RELATED TO EXTRAMEDICAL USE OF ANALGESICS NIDA Women and Gender Junior Investigator Travel Award, 2007 1 RO3 DA023434- 01A1 Martins (PI) 09/01/08 – 06/30/10 TRENDS IN NONMEDICAL PRESCRIPTION DRUG USE AND ABUSE/DEPENDENCE AMONG ADOLESCENTS 1 RO1 NICHD HD060072 Martins (PI) 03/01/09 – 02/28/13 PREDICTORS OF PATHOLOGICAL GAMBLING AMONG AFRICAN-AMERICAN YOUNG ADULTS

PUBLICATIONS

Journal Articles (signifies peer review)

Published or In Press Martins SS, Lobo DSS, Tavares H, Gentil V. Pathological gambling in women: a review. Rev. Hosp. Clín. Fac. Med. S. Paulo 2002; 57(5):235-242. Tavares H, Martins SS, Zilberman ML, el-Guebaly N. Gamblers and treatment-seeking: why haven’t they come earlier? Addictive Disorders and Their Treatment 2002; 1(2):65-69. Tavares H, Martins SS, Lobo DS, Silveira C, Gentil V, Hodgins D. Factors at play in faster progression for female pathological gamblers: an exploratory analysis. Journal of Clinical Psychiatry 2003; 64 (4): 433-438.


Martins SS, Tavares H, Lobo DS, Galleti AM, Gentil V: Pathological gambling, gender and risk-taking behaviors Addictive Behaviors 2004; 29(6): 1231-1235. Martins SS, Mazzotti G, Chilcoat HD. Trends in Ecstasy use in USA from 1995 to 2001: comparison with marijuana users and association with other drug use. Experimental and Clinical Psychopharmacology 2005; 13(3): 244-52. Martins SS, Mazzotti G, Chilcoat H. Recent-onset Ecstasy users: association with other drug use, psychiatric comorbidity and deviant behaviors. Experimental and Clinical Psychopharmacology, 2006; 14(3): 275-86. Martins SS, Copersino M, Soderstrom CA, Smith GS, Dischinger PC, McDuff DR, Hebel JR, Kerns TJ, Ho SM, Read KM, Gorelick DA. Risk of psychoactive substance dependence in a trauma inpatient population. Journal of Addictive Diseases, 2007; 26(1): 71-77. Martins SS, Copersino M, Soderstrom CA, Smith GS, Dischinger PC, McDuff DR, Hebel JR, Kerns TJ, Ho SM, Read KM, Gorelick DA. Sociodemographic characteristics associated with drug use status in a trauma inpatient population. Journal of Addictive Diseases, 2007; 26(2):53-62. Martins SS, Ghandour L, Chilcoat H. Pathways in Ecstasy use and other drug use. Addictive Behaviors, 2007; 32(7):1511-8. Martins SS, Storr CL, Ialongo NS, Chilcoat HD. Mental health and gambling in urban female adolescents. Journal of Adolescent Health, 2007; 40(5): 463-5. Martins SS, Ghandour L, Chilcoat H. Profile of Dependence Symptoms among Extramedical Analgesic Users. Addictive Behaviors, 2007; 32(10):2003-19. da Silva Lobo DS, Vallada H, Knight J, Martins SS, Tavares H, Gentil V, Kennedy J. Dopamine genes and pathological gambling in discordant sib-pairs. Journal of Gambling Studies, 2007; 23(4):421-433. Ghandour L, Martins SS, Chilcoat HD. Understanding the patterns and distribution of opioid analgesic dependence symptoms using a latent empirical approach. International Journal of Methods in Psychiatry Research, 2008; 17(2):89-103. Martins SS, Storr CL, Ialongo NS, Chilcoat HD. Gender differences in mental health characteristics and gambling among African-American adolescent gamblers. American Journal on Addictions, 2008; 17 (2):126-134. Martins SS, Storr CL, Alexandre PK, Chilcoat HD. Do adolescent Ecstasy users have different attitudes towards drugs when compared to Marijuana users? Drug and Alcohol Dependence, 2008, 94(1-3):63-72. Martins SS, Storr CL, Alexandre PK, Chilcoat HD. Adolescent Ecstasy use in the National Survey of Parents and Youth: the role of sensation-seeking, peer drug use and parental monitoring. Addictive Behaviors, 2008, 33(7):919-33. Keyes KM, Martins SS, Hasin DS. Prevalence, correlates, and comorbidity of ecstasy use among young adults in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Drug and Alcohol Dependence, 2008, 97(1-2):139-49.


Martins SS, Storr CL, Zhu H, Chilcoat HD. Correlates of extramedical use of Oxycontin® and other analgesic opioids among the US general population. Drug and Alcohol Dependence, 2009, 99(1-3):58-67. Martins SS, Alexandre PK. The association of Ecstasy use and academic performance among adolescents in two U.S. national surveys. Addictive Behaviors, 2009, 34(1):9-16. Alexandre PK, Patrick R, Beauliere A, Martins SS. Race differentials in employment effects of psychological distress: a study of non-Hispanic Whites and African-Americans in the United States. The Social Science Journal, 2009, 49:201-210. Eaton WW, Martins SS, Nestadt G, Bienvenu OJ, Clarke D, Alexandre PK. The Burden of Mental Disorders. Epidemiologic Reviews, 2008, 30:1-14. Martins SS, Keyes KM, Storr CL, Zhu H, Chilcoat HD. Pathways between nonmedical opioid use/dependence and psychiatric disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions . Drug and Alcohol Dependence, 2009, 103(1-2):16-24. Alexandre PK, Martins SS, Patrick R. Disparities in Adequate Mental Health Care for Past-Year Major Depressive Episodes among Caucasian and Hispanic Youth. Psychiatric Services, 2009, 60(10):1365-71.

Hedden SL, Martins SS, Malcolm RJ, Floyd L, Cavanaugh CE, Latimer WW. Patterns of illegal substance use in an alcohol dependent population: Results from the National Survey on Drug Use and Health. Drug and Alcohol Dependence, in press. Severtson G, Hedden SL, Martins SS, Latimer WW. Patterns of cognitive impairments among heroin and cocaine users: The association with self-reported learning disabilities and infectious disease. Journal of Learning Disabilities, in press. Under review Kuramoto SJ, Martins SS, Ko J, Chilcoat HD. Past year treatment status and pattern of alcohol abuse symptoms among US adults with alcohol dependence. Martins SS, Ghandour LA, Storr CL. Socio-demographic and substance use correlates of gambling behavior in the Canadian general population. Martins SS, Ghandour LA, Storr CL. Gambling behavior subtypes in the Canadian general population. Martins SS, Storr CL, Zhu H, Alexandre PK, Chilcoat HD. Changes in the profile of recent-onset extramedical opioid analgesic use in the US from 1991 to 2006. Martins SS, Keyes KM, Storr CL, Zhu H, Grucza RA. Birth cohort trends in lifetime and past-year nonmedical opioid use disorders: results from two national surveys.

Fiestas F, Radovanovic M, Martins SS, Medina-Mora ME, Posada-Villa J, Anthony JC, & the World Mental Health Consortium. Cross-national differences in cannabis problem experience.


Keyes KM, Martins SS, Hatzenbuehler, ML, Blanco C, Hasin DS. Mental health service utilization for psychiatric disorders among Hispanics living in the United States: differences by ethnic subgroup, ethnicity of social network, perceived discrimination and ethnic identification. Ko J, Martins SS, Kuramoto SJ, Chilcoat HD. Patterns of alcohol dependence symptoms using a latent empirical approach: associations with treatment usage and other correlates. Keyes KM, Martins SS, Blanco C, Hasin DS. Challenging the paradigm of a “telescoping” phenomenon in gender differences for substance disorders: results of a cohort analysis in the U.S. population. Fenton M. Keyes KM, Martins SS, Hasin DS. Non-medical Prescription Anxiety Medication Use among Individuals with a Prescription; Prevalence and Correlates. Hedden SL, Martins SS, Malcolm RJ. Race/ethnicity Differences between Alcohol, Drug and Co-Occurring Alcohol and Drug Use Disorders and their Association with Comorbidities: A Study from the National Survey on Drug Use and Health. Martins SS, Liu SM, McCabe SE, Blanco C. Impairment, insurance status, and treatment-seeking behavior associations with prescription opioid use disorder in the United States: Results from the National Epidemiologic Study on Alcohol and Related Conditions. In preparation Lobo DSS, Martins SS, Tavares H, Vallada HP, Gentil V. Identifying vulnerability to pathological gambling through personality dimensions. Martins SS, Gorelick DA. Drug use conditional dependence of Drug use by Psychiatric Disorders in the National Epidemiologic Study of Alcohol and related conditions. Ghandour LA, Ko J, Chilcoat HD, Martins SS. Evidence for an opioid analgesic dependence syndrome developing soon after onset of extramedical opioid analgesic use. Martins SS, Keyes KM, Storr CL, Zhu H, Chilcoat HD. Longitudinal associations of extramedical opioid analgesic use/dependence and psychiatric disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Martins SS, Alexandre PK, Falck RS, Carlson RG. Perceived risk associated with Ecstasy use: a latent class analysis approach. Andrade LH, Silveira CM, Martins SS, Wang WP, Andrade AG. Drinking patterns and alcohol-related problems in the São Paulo Catchment area study: gender differences Radovanovic M, Martins SS, Anthony JC. A nested case-control study of pathological gambling. Blanco C, Martins SS, et al. Predictors of transition from gambling to pathological gambling. Severtson G, Martins SS, Latimer WW. The associations between learning disabilities and DSM-IV substance dependence in the National Comorbidity Survey Replication. Kuramoto SJ, Ko J, Chilcoat HD, Martins SS. Gender differences in suicidal ideation and opioid use disorder among non-medical opioid users with lifetime major depression.


Nower L, Martins SS, Blanco C. The gambling pathways model applied to the NESARC data. Mancha BE, Hedden SL, Martins SS, Latimer WW. A latent class analysis of Alcohol Abuse and Dependence criteria among youths in the National Survey of Drug Use and Health: implications for the DSM-V. Lee SY, Lee HB, Keyes KM, Martins SS.Lifetime and Twelve-month Prevalence of Psychiatric Disorders and Mental Health Service Utilization among Asians Subgroups in the United States. Lee GP, Storr CL, Ialongo NS, Martins SS. Compounded Effect of Childhood Depressive Symptoms and Impulsivity on Adolescent Gambling: A Longitudinal Study. Books or Monographs Antoniuk AS, Martins SS, Silva Prado H. Guia para diagnóstico e tratamento da síndrome de tourette. “Guide to diagnosis and treatment of Tourette Syndrome”, Janssen-Cilag, 2001. 40p. (in Portuguese).

Chapters

Martins SS. Emergências relacionadas a Drogas Sintéticas. In: Martins HS, Damasceno MCT & Awada, SFCB. Diagnóstico e Tratamento em Emergências- Condutas do HCFMUSP, Editora Manole, Barueri, Seção VIII - Emergências Psiquiátricas e Intoxicações exógenas agudas, Capítulo 143, págs. 848-856, 2006.[in Portuguese, chapter 143, pp. 848-856, 2006. Medical emergencies related to the use of Club Drugs, In: Diagnosis and treatment of medical emergencies- guidelines of the Hospital of University of São Paulo Medical School]. Martins SS. Emergências relacionadas a Drogas Sintéticas. In: Martins HS, Damasceno MCT & Awada, SFCB. Diagnóstico e Tratamento em Emergências- Condutas do HCFMUSP- 2ª Edição Revisada e Ampliada, Editora Manole, Barueri, Seção VIII - Emergências Psiquiátricas e Intoxicações exógenas agudas, Capítulo 211, págs.1584-1592, 2008.[in Portuguese, chapter 211, pp.1584-1592, 2008. Medical emergencies related to the use of Club Drugs, In: Diagnosis and treatment of medical emergencies- guidelines of the Hospital of University of São Paulo Medical School- 2nd Edition revised & updated]. Andrade LH, Silveira CM, Martins SS, Storr CL, Wang WP, Viana MC. Problems related to binge drinking in Brazil [Padrões de consumo do álcool e problemas decorrentes do beber pesado episódico no Brasil] in: Anthony JC & Andrade AG, Health problems caused by harmful alcohol consumption. ICAA, 2009 (book published in bilingual version English & Portuguese). Martins SS, et al. Population Disparities in Mental Health. In: Eaton WW, Public Mental Health. In Preparation. Martins SS, Mazzotti G, Chilcoat HD. Trends in Ecstasy use in USA from 1995 to 2001: comparison with marijuana users and association with other drug use. In: Marlatt AG, Witkiewitz K, Editors. Addictive Behaviors: New Readings on Etiology Prevention and Treatment. American Psychological Association, 2008. Martins SS, Mazzotti G, Chilcoat HD. Trends in Ecstasy use in USA from 1995 to 2001: comparison with marijuana users and association with other drug use. In: Natajaran M, Editor.


Drugs of Abuse: The International Scene, 1st Edition (part of the Library of Drug Abuse and Crime Series).

CURRICULUM VITAE

SILVIA S. MARTINS, M.D., P.H.D

PART II

TEACHING

Thesis Advisory Committee & Final Defense Committee

Kamini Shah- PhD Candidate, Department of Health Behavior and Society- defense date 01/13/09

S. Geoff Severtson- PhD Candidate, Department of Mental Health- defense date 06/01/09

MHS student mentor

2008-2009- Grace Lee, MHS Candidate, Department of Mental Health

2009-2010- Ashley Jaramillo, MHS Candidate, Department of Mental Health

Special Studies Advisor

2007-2008- 4th term- S. Janet Kuramoto, Department of Mental Health

2008-2009- 2nd term- S. Janet Kuramoto, Department of Mental Health

2008-2009- 3rd term- S. Janet Kuramoto, Department of Mental Health

2008-2009- 4th term-Su Yeon Lee, Department of Mental Health

2009-2010- 1st term-Su Yeon Lee, Department of Mental Health

Other Significant Teaching

2001-2003- Teaching Assistant- General Psychiatry to 4th year Medical students, University of São Paulo Medical School, Brazil (responsible for lecture preparations, several lecture presentations and patient interviews during classes).

Topics: Depressive disorders Anxiety disorders Substance-related disorders - Treatment Volition and impulsivity Personality disorders Pathological gambling and other impulse control disorders

2005- Guest Lecturer at JHSPH Department of Mental Health’s course 330.643 “Alcohol, Tobacco and other drugs and public health, (graduate level: 25 students), Baltimore, MD, October 5th, 2005.

Gambling disorders among African-American adolescents: association with drug use, drug abuse/dependence and deviant behaviors.


2005- Guest Lecturer at JHSPH Department of Mental Health’s course 330.643 “Alcohol, Tobacco and other drugs and public health, (graduate level: 25 students), Baltimore, MD, October 5th, 2005. Recent-onset Ecstasy users: association with other drug use, psychiatric comorbidity and

deviant behaviors. 2005- Guest Lecturer at JHSPH Department of Mental Health’s course “Epidemiology of Drug and Alcohol Dependence, (graduate level), Baltimore, MD, November 29th, 2005.

Ecstasy use in the USA from 1995 to 2001: comparison with marijuana users and association with other drug use.

2006- Guest Lecturer at the Department of Psychiatry, University of São Paulo Medical School, Weekly Seminar Series, São Paulo, SP, Brazil, March 9th, 2006.

Epidemiology of drug use in the US: special emphasis on the Ecstasy and Analgesic Opioid Epidemics

2007- Guest Lecturer at the Brown Bag Seminar Series, Department of Epidemiology, College of Human Medicine, Michigan State University, East Lansing, MI, April 11th 2007.

Epidemiology of Ecstasy use in the USA: trends, pathways between Ecstasy and other drug use & association with deviant behaviors

2007- Guest Lecturer at JHSPH Department of Mental Health’s course 330.643 “Alcohol,

Tobacco and other drugs and public health (graduate level: 30 students), Baltimore, MD, October 3rd, 2007. Conditional substance dependence by psychiatric diagnosis in the US population.

2008- Guest lecturer at the NESARC Users Meeting- Panel 2: Examples of Analytic Methodologies Applied to NESARC, Bethesda, MD, March 4-5 2008.

Survival Analysis Approach to Test for Bi-Directional Pathways in NESARC Data, 2008- Co-chair and lecturer- Workshop: Step-by-step guide to analysis of epidemiological field survey data on minority health disparities and male-female differences in NIDA-related outcomes. 70th College on Problems of Drug Dependence Annual meeting, CPDD, San Juan, Puerto Rico, June 16 2008.

It’s about the basics: Using a generalized linear model to control covariates. 2008- Guest Lecturer at JHSPH Department of Mental Health’s course 330.602

“Epidemiology of Drug Dependence” (graduate level: 25 students), Baltimore, MD, November 4th, 2008. Recent Trends in Nonmedical Opioid Analgesic Use in the USA

2008- Guest Lecturer at the Department of Psychiatry, ABC region Medical School, São Paulo, Brazil, November 11th 2008- weekly seminars for Residents and Faculty.

Research on Brazilian Medical students’ stigma towards psychiatric conditions: a pilot project

2008- Guest Lecturer at the Department of Psychiatry, Pontifícia Universidade Católica do Paraná (PUC-PR), Curitiba, Brazil, November 26th 2006, weekly seminars for Residents and Faculty.

Basic principles for research in the area of Psychiatric Epidemiology and Drug Dependence Epidemiology

2009- Lecturer at JHSPH Department of Mental Health’s Graduate students seminar (graduate level: 20 students), Baltimore, MD, March 10th, 2009.


How to use Survey design commands when analyzing Survey Data with Stata

2009- Lecturer at JHSPH Department of Mental Health’s Drug Dependence Epidemiology Training Program Seminar Series (graduate level: 10 students), Baltimore, MD, May 21st, 2009. Latent Class Analysis

2009- Guest Lecturer (videoconference) at the Department of Psychiatry, University of São Paulo, Brazil, Alcohol and Drugs graduate course (graduate level: 15 students), São Paulo, Brazil, September 16th 2009.

Epidemiology of Ecstasy Use in the USA

RESEARCH GRANT PARTICIPATION

Active 1 RO1 NICHD HD060072 Martins (PI) 03/01/09 – 02/28/13 PREDICTORS OF PATHOLOGICAL GAMBLING AMONG AFRICAN-AMERICAN YOUNG ADULTS Total costs: $906,100 The objectives of this study are to: 1) estimate prevalence and incidence rates of recreational gambling and gambling problems (problem and pathological gambling) among an epidemiologic sample of African-American young adults and assess changes in the association between basic demographic characteristics with recreational gambling and gambling problems at age 20-21 as compared to associations found at age 16-17and age 18-19; 2) identify different trajectories of aggressive behaviors, hyperactivity and impulsivity at childhood and adolescence and test whether specific trajectories are associated with increased risk of recreational gambling and gambling problems in young adulthood; 3) identify different late-adolescent and young adult trajectories of gambling behavior; 4) test whether past-year precipitating stress is associated with recreational gambling and gambling problems in young adulthood and estimate the strength of these associations; 5) assess the comorbid prevalence and strength of association of tobacco, alcohol, and drug involvement and psychiatric disorders with recreational gambling and problem/pathological gambling; 6) describe the eolving natural history of gambling involvement and development of gambling disorders by following the time course of clinical features associated with gambling. Role: Principal Investigator 1 RO3 DA023434- 01A1 Martins (PI) 09/01/08 – 06/30/10 TRENDS IN NONMEDICAL PRESCRIPTION DRUG USE AND ABUSE/DEPENDENCE AMONG ADOLESCENTS Total costs: $164,000 This study will: 1) estimate associations of non-medical prescription drug use with demographic characteristics, deviant behaviors, sensation-seeking, and mental health treatment and to test whether these associations change over time, 2) explore polydrug use patterns among nonmedical prescription drug users and investigate for different correlate associations (within different polydrug use subgroups and test whether these associations change over time, 3) test for variation in the prevalence of non-medical prescription drug use and factors associated with nonmedical prescription drug use by age and gender subgroups, 4) estimate the prevalence of nonmedical prescription drug abuse and dependence over time and examine whether the prevalence of abuse and dependence among nonmedical prescription drug users has changed over time as well as investigate associations of non-medical


prescription drug abuse/dependence with other correlates, 5) explore the prevalence and different patterns of polydrug abuse/dependence among adolescents who meet criteria for nonmedical prescription drug abuse /dependence over time, and test for different covariate associations. Role: Principal Investigator 1 R21 DA020667-01A2 NIDA Martins (PI) 05/15/07– 04/30/10 NCE TRENDS IN PROBLEMS RELATED TO EXTRAMEDICAL USE OF ANALGESICS Total costs: $427,739 The objectives of this study are to: 1) test for changes in characteristics of extramedical analgesic users over time, 2) test for potential causal pathways between psychiatric disorders and extramedical analgesic use and abuse/dependence, 3) estimate the distribution of symptoms of extramedical analgesic abuse/dependence in the U.S. household population, 4) test for categories of problem extramedical analgesic use based on observed clustering of symptoms of analgesic abuse/dependence and identify factors associated with analgesic abuse/dependence. Role: Principal Investigator 1 RO1 DA020630-01A2 NIDA Alexandre (PI) 05/29/07 – 04/30/10 ECONOMIC ASPECTS OF ECSTASY USE Total costs: $934,323 The major goals of this project are: (1) to estimate the extent to which ecstasy use contributes to more health services utilization and cost among adolescents and young adults; (2) to estimate the extent to which ecstasy use contributes to criminal activities and related costs among adolescents and young adults; (3) to investigate the relationships between ecstasy use and academic performance among high school students. Role: Co-investigator PRESCRIPTION DRUG USE AMONG COLLEGE STUDENTS IN LEBANON: PREVALENCE, PATTERNS, AND CORRELATES OF MEDICAL AND NON-MEDICAL USE AND DIVERSION Ghandour (PI) 10/01/09- 09/30/10 Seed grant funded by the American University of Beirut Total costs: $7,000 The current study proposes to examine: (1) the prevalence and pattern of the medical and non-medical use of classes of “controlled” psychoactive prescription drugs; (2) the extent of diversion of these prescription drugs; (3) the current perceived availability, ease and source of purchase, as well reasons for the use and misuse; and (4) the associations between the medical and non-medical use of these drugs and several other relevant correlates, including demographics and other youth problem behaviors such as the use of other substances. Data will be collected from approximately 25% of the student population of a large private university in Beirut using a proportionate cluster sampling technique to represent all Faculties. Role: Co-investigator Completed 1RO3 DA020923-01 Martins (PI) 09/30/05 – 06/30/08- NCE National Institute on Drug Abuse Total costs: $161,329 PREDICTORS OF ADOLESCENT ECSTASY USE IN THE NATIONAL SURVEY OF PARENTS AND YOUTH Objective: The aims of this project are to: 1) test for changes in ecstasy use and in attitudes and beliefs towards ecstasy use among adolescents over time; 2) test whether previous deviant behaviors, previous high sensation-seeking scores and use and level of use of other drugs


predict future ecstasy use among adolescents; 3) test whether previous low levels of parent monitoring and high levels of peer ecstasy use predict future ecstasy use among adolescents. Role: Principal Investigator 1 Ontario Problem Gambling Research Centre grant Martins (PI) 03/31/07- 03/30/08 Total costs: $36,061 SUBTYPING GAMBLING BEHAVIORS IN THE CANADIAN GENERAL POPULATION This study aims to: 1) Identify different gambling subtypes among gamblers in the general population via Latent Class Analysis (categorical approach) based on regional and demographic (age, racial/ethnic) characteristics, age of onset of gambling, type of gambling activities preferred, amount of money spent on gambling, gambling frequency, main reason to gamble, past-year psychiatric symptoms, past-year substance use, and family history of problem gambling; 2) Investigate how these subtypes correlate with CPGI scoring of gambling dimensions (from no-gambling to problem gambling) and how they correlate with specific CPGI scored items.; 3) Test for gender differences in the gambling subtypes identified by LCA and gender-specific associations with CPGI scored dimensions and specific CPGI scored items. Role: Principal Investigator UNDERSTANDING CLUSTERING OF DEPENDENCE SYMPTOMS ACROSS DRUG TYPES (05/01/07 – 08/30/07) GlaxoSmithKline Principal Investigator: Silvia S. Martins. Total costs: $40,000 Objective: To examine the distribution and clustering of symptoms of dependence due to use of alcohol, tobacco, marijuana, cocaine, heroin and extramedical use of analgesics using the NSDUH 2002-2005 datasets. Role: Principal Investigator Incentive grant for Young investigators Award- Institute for Research on Pathological gambling and related disorders, Division on Addictions, Harvard Medical School, (09/012004-12/31/2005) PREVALENCE OF GAMBLING DISORDERS, ASSOCIATION WITH DRUG USE & PSYCHIATRIC COMORBIDITY IN ADOLESCENTS LIVING IN BALTIMORE ($23,000) Objective: This study aims to estimate the prevalence rates of gambling habits & gambling disorders and to investigate the cross-sectional and longitudinal association of gambling disorders with drug use, psychiatric comorbidity, different levels of parent monitoring and deviant peer relationship among adolescents living in Baltimore a sample of 515 17 year-old youth (90% of them are African American) from Baltimore City. Role: Principal Investigator AN EPIDEMIOLOGIC INVESTIGATION OF PROBLEMS RELATED TO MISUSE OF ANALGESICS (11/01/05 – 6/01/05) Janssen Pharmaceuticals Principal Investigator: Howard D. Chilcoat, Sc.D. ($50,000) Objective: To examine the distribution and clustering of symptoms of abuse and dependence due to extramedical use of analgesics. Role: Co- Principal Investigator Postdoctoral Overseas Research Scholarship, National Council of Research (CNPq- Brazil) CNPq 20.018/2004-0 from 08/01/04 – 07/31/05 PROJECT: EPIDEMIOLOGY OF ECSTASY USE: COMPARISON WITH MARIJUANA USERS AND ASSOCIATION WITH OTHER DRUG USE, ABUSE AND DEPENDENCE. Objective: This study is post-doctoral scholarship to conduct a secondary data analysis of the National Household Survey of Drug Use (NHSDA) and analyzes trends in ecstasy use as well as subgroups of ecstasy users Role: Principal Investigator


Pre-Doctoral Research Scholarship, São Paulo Research Council (FAPESP), Brazil FAPESP 02/02650-8 & 00/14215-9 from 01/01/00 – 31/08/03 PATHOLOGICAL GAMBLING IN WOMEN: CLINICAL AND PERSONALITY FEATURES (Ph.D. dissertation) Objective: The goal of this project was to study sociodemographic, clinical and psychiatric comorbidity as well as personality features of males and females who sought treatment at the Pathological Gambling Unit - Institute of Psychiatry -University of São Paulo Medical School, Brazil Pending 1 RO1 NIDA Martins & McCabe (Multiple PI) 07/01/10- 06/30/14 PRESCRIPTION DRUG DIVERSION AMONG ADOLESCENTS AND YOUNG ADULTS The proposed research will focus on prescription opioids, sedatives, stimulants, and tranquilizers, because these four medication classes have high rates of nonmedical use among adolescents and young adults, high abuse potential, and adolescents and young adults are often prescribed these medications for legitimate health conditions. Existing data from the College Student Life Survey, Monitoring the Future, National Survey on Drug Use and Health, and Secondary Student Life Survey provide an unprecedented opportunity to examine research questions that will lead to a more comprehensive understanding of prescription drug diversion. The objective of the proposed secondary data analysis is to better understand the magnitude of prescription drug diversion among adolescents and young adults. To meet this objective, we propose using data collected between 2005 and 2009 from over 40,000 adolescents and young adults in the United States. The proposed study aims to: 1) examine the sources of diverted medications among nonmedical users; 2) explore different diversion sources among adolescents and young adults by DSM-IV substance use disorder status (e.g., nonmedical users with a DSM-IV substance use disorder and nonmedical users without a DSM-IV substance use disorder); and 3) identify diversion behaviors associated with medical use of prescription medications. Role: Principal Investigator 1 RO1 NIDA Alexandre (PI) 11/01/09-10/31/13 LONG TERM ECONOMIC CONSEQUENCES OF DRUG ABUSE: THE ROLE OF RACE/ETHNICITY Role: Co- Investigator 1 Challenge Grant- NIDA Richard (PI) 09/30/09-08/31/11 THE EFFECTS OF ADOLESCENTS’ MARIJUANA USE WITH CO-MORBID CONDUCT DISORDERS (CD) ON THEIR MOTHERS’ LABOR SUPPLY Role: Co- Investigator 1R21-NIH Surkan (PI) 04/01/10-03/31/12 OBESITY AND PSYCHIATRIC/SUBSTANCE USE DISORDERS: A LONGITUDINAL STUDY Role: Co- Investigator We propose to test 1) whether overweight/obesity predicts incidence of psychiatric disorders and SUDs, 2) whether prior psychiatric disorders and SUDs predict future incidence of overweight/obesity, and 3) whether weight discrimination is associated with psychiatric disorders/SUDs among overweight/obese individuals. BMI will also be used as a continuous variable in order to assess weight gain. Finally, we will examine the role of potential


mediators and modifiers of the associations between overweight/obesity and psychiatric disorders/SUDs by assessing the role of weight discrimination, disability, distress, and social networks. Because the perception of acceptable body size appears to differ according to demographic factors, we will also examine gender, race/ethnicity, socio-economic status, and age cohort as possible effect modifiers. This study is based on two population-based longitudinal data sets, the Baltimore Epidemiologic Catchment Area (Baltimore-ECA) and the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). The NESARC is a nationally representative longitudinal study of adults (≥ 18 years old) in the non-institutionalized US population with detailed information on psychiatric disorders, SUDs, weight discrimination, body mass index (BMI), and other demographic information. It is based on a multistage design sampling the civilian non-institutionalized household population of adults who participated in 2001-2002 and 2004-2005 (N=34,653 at follow-up). The Baltimore ECA is a population-based cohort including a wide range of psychopathology and BMI from which we will use data from 1993-96 and 2004-5 (N=1,071 at follow-up). Pilot project, not yet submitted to request NIH funding, currently funded with Michigan State University Research Funds, Anthony & Martins (PIs) RESEARCH ON BRAZILIAN MEDICAL STUDENTS’ STIGMA TOWARDS PSYCHIATRIC CONDITIONS: A PILOT PROJECT The topics of the proposed research are high priority psychiatry research topics. Four conditions will be investigated in six different Brazilian medical schools: (a) tobacco smoking and related morbidity and mortality, (b) depressive illnesses, and (c) drinking of alcoholic beverages. All three of these conditions are ranked in the top 10 conditions that contribute to the global burden of diseases, or are slated to move into the top 10 category for all countries during the span of time from the present until 2030. Role: Co- Principal Investigator

PRESENTATIONS

Scientific Meetings

Oral Presentations

Chilcoat HD, Dasgupta N, Martins, SS. Testing pathways between alcohol and opioid dependence. 71st College on Problems of Drug Dependence Annual meeting, CPDD, Reno, Nevada, June 21 2009 (presented by Chilcoat HD). Martins SS, Alexandre PK. The association of Ecstasy use and academic performance among adolescents in two U.S. national surveys. Addiction Health Services Research Conference, Boston, Massachusetts, October 22 2008 (presented by Alexandre PK). Martins SS, Storr CL, Zhu H & Chilcoat HD. Trends in recent-onset extramedical opioid analgesic use in the US from 1991 to 2006. 70th College on Problems of Drug Dependence Annual meeting, CPDD, San Juan, Puerto Rico, June 19 2008. Martins SS. Extramedical use of analgesics in the NSDUH. In: Anthony J, Breslau N, Chilcoat H, Compton W, Martins S, & Weissman M. The National Survey of Drug Use and Health: a missed opportunity for phase IV post-marketing studies and etiological research? American College of Neurophsychopharmacology 46th Annual Meeting, December 10, 2007. Martins SS, Gorelick DA. Gender differences in conditional substance dependence by psychiatric diagnosis in the US population. 69th College on Problems of Drug


Dependence Annual meeting, CPDD, Quebec City, Canada, June 18 2007 (also acted as Co-Chair of oral presentation session).

Lobo DS, Martins S, Tavares H, Kennedy J, Vallada H, Gentil V. Personality and psychiatric co-morbidity discriminates pathological gamblers among same-sex sibling pairs 69th College on Problems of Drug Dependence Annual meeting, CPDD, Quebec City, Canada, June 18 2007.

. Martins SS. Gender differences in adolescent gambling in inner-city youth. 21st Annual Conference on Problem Gambling Prevention, Research, Recovery and Treatment. National Council of Problem Gambling Annual Meeting, Kansas City, MO, June 09, 2007. Martins SS. Predictors of adolescent Ecstasy use as compared to other illegal drug use in the National Survey of Parents and Youth. Presented at the NSPY Users Group Annual Meeting, Bethesda, MD, May 14 2007. Martins SS. Female Pathological gambling: epidemiology, clinical features and treatment. III Foro Internacional de Transtornos Adictivos “Adicciones Comportamentales: Juego patológico” (Third International Forum of Addictive Disorders, Behavioral Addictions: Pathological Gambling). Sociedad Española de Toxicomanías (Spanish Society of Drug use Disorders), Valencia, Spain, September 22nd 2006 (invited conference speaker).

Martins SS, Ghandour LA, Chilcoat HD. Profile of dependence symptoms among extramedical analgesic users In: Research Colloquium for Young Investigators, American Psychiatric Association Annual Meeting (APA), Toronto, Canada, May 21st 2006.

Martins SS, Mazzotti G, Chilcoat HD. Recent-onset Ecstasy users: association with other drug use, psychiatric comorbidity and deviant behaviors. In: U.S. Patterns of Club Drug Use, American Public Health Association, APHA, Philadelphia, PA, December 13th 2005. Martins SS, Mazzotti G, Chilcoat HD. Ecstasy use and its associations with alcohol use/binge drinking: results from a national survey. American Public Health Association, APHA, Washington, DC, November 8th, 2004.

Martins SS, Mazzotti G, Chilcoat HD. Epidemiology of Ecstasy use in the USA & its relationships with other drug use, abuse/dependence & disruptive behaviors. College on Problems of Drug Dependence, CPDD, San Juan, PR, June 16th, 2004.

Martins SS, Mazzotti G, Chilcoat HD. Ecstasy use in the USA from 1995 to 2001: comparison with marijuana users and association with other drug use. In: Research Colloquium for Young Investigators, American Psychiatric Association Annual Meeting (APA), New York, NY, May 2nd 2004.

Martins SS, Mazzotti G, Chilcoat HD. Ecstasy use in the USA from 1995 to 2001: comparison with marijuana users and association with other drug use. In: Wednesday Noontime Seminars, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, 7th April 2004

Martins SS, Lobo DSS, Tavares H, Gentil V. Female Pathological gambling: clinical and personality features. In: 2nd World Congress of Women’s Mental Health. Washington, DC, March 2004


Martins SS, Tavares H, Lobo DS, Galleti AM, Gentil V. Pathological gambling, gender and risk-taking behaviors. In: 45th International Conference in the Prevention and Treatment of Dependencies-ICAA, São Paulo, Brazil, December 2002.

Martins SS. Jogo patológico em mulheres. “Pathological gambling in women”, In: XIX Brazilian Congress of Psychiatry, Recife, October 2002.

Martins SS. Jogo patológico em mulheres: características clínicas. “Pathological gambling in women: clinical features”, In: VII Brazilian Congress of Clinical Psychiatry, Campinas, June 2002.

Abstracts

Kuramoto SJ, Chilcoat HD, Ko J, Martins SS. Gender differences in suicidal ideation and

opioid use disorder in non-medical opioid users with lifetime major depression. 71st College on Problems of Drug Dependence Annual meeting, CPDD, Reno, Nevada, June 22 2009.

Ko J, Martins SS, Kuramoto SJ, Chilcoat HD. Gender differences in patterns of alcohol dependence symptoms: Evidence from a latent empirical approach. 71st College on Problems of Drug Dependence Annual meeting, CPDD, Reno, Nevada, June 22 2009. Martins SS, Severtson SG, Fenton M, Lee GL, Storr CL. Cohort differences in nonmedical prescription drug use in adolescence. 71st College on Problems of Drug Dependence Annual meeting, CPDD, Reno, Nevada, June 23 2009. Lee GP, Ialongo NS, Martins SS. Compounded effect of childhood depressive symptoms and impulsivity on adolescent gambling: a longitudinal study. 2009 NIDA International Forum, Reno, Nevada, June 21 2009. Martins SS, Keyes KM, Storr CL, Zhou H, Grucza RA. Birth cohort trends in lifetime and non-medical opioid use and past-year nonmedical opioid use disorders: results from two national surveys. 17th Annual meeting of the Society for Prevention Research, May 27, 2009. Alexandre PK, Martins SS, Richard P. Disparities in adequate mental health among White and Non-White youth. 17th Annual meeting of the Society for Prevention Research, May 27, 2009. Hedden S, Martins SS, Malcolm RJ, Floyd L, Latimer WW. Latent class patterns of illegal substance use in an alcohol dependent population: results from the National Survey of Drug Use and Health. 17th Annual meeting of the Society for Prevention Research, May 27, 2009. Severtson SG, Martins SS, Latimer WW. The associations between learning disabilities and DSM-IV substance dependence in the National Comorbidity Survey Replication. 17th Annual meeting of the Society for Prevention Research, May 27, 2009. Andrade LH, Silveira CM, Martins SS, Wang YP, Andrade A, Viana MC. A population-based study on heavy episodic drinking among Brazilian adults: Evidence from the São Paulo Megacity Mental Health Survey. 17th Annual meeting of the Society for Prevention Research, May 26, 2009. Keyes KM, Martins SS, Hasin DS. Challenging the paradigm of a “telescoping” phenomenon in gender differences for substance disorders: results of a cohort analysis in the


U.S. population. XII International Congress of the International Federation of Psychiatric Epidemiology,Vienna, Austria, April 16-19 2009. Hedden, SL, Martins SS, Malcom RJ, Latimer WW. Race/ethnicity Differences betweenAlcohol, Drug and Co-Occurring Alcohol and Drug Use Disorders and their Association with Comorbidities: A Study from the National Survey on Drug Use and Health. Addiction, Infection Diseases and Public Health, 3rd Annual Conference, Baltimore, MD, JHSPH, April 24, 2009. Mancha BE, Hedden SL, Martins SS, Latimer WW. A latent class analysis of Alcohol Abuse and Dependence criteria among youths in the National Survey of Drug Use and Health: implications for the DSM-V. American Psychopathological Association, 99th Annual Meeting, New York City, March 5, 29 2009. Keyes KM, Martins SS, Hasin DS. Challenging the paradigm of a “telescoping” phenomenon in gender differences for substance disorders: results of a cohort analysis in the U.S. population. American Psychopathological Association, 99th Annual Meeting, New York City, March 5, 29 2009. Ghandour LA, Martins SS, Storr CL. Gender differences in problem gambling and comorbid substance use behaviors in the Canadian general population. 70th College on Problems of Drug Dependence Annual meeting, CPDD, San Juan, Puerto Rico, June 19 2008. (poster presentation). Ghandour LA, Martins SS, Storr CL. Subtypes of Gambling behaviors in the Canadian general population: a latent class approach. Society for Prevention Research 16th Annual Meeting. May 28-30, 2008, San Francisco, CA, USA. (poster presentation). Martins SS, Chilcoat HD. Sensation-seeking as a predictor of substance use transitions in the National Survey of Parents and Youth. 2007 NIDA International Forum, Quebec City, Canada, June 17 2007 (poster presentation).

Bustamante I, Fiestas F, Martins SS, Storr CL. Is spending time with gang members as friends associated with drug use among school-attending youth? 2007 NIDA International Forum, Quebec City, Canada, June 18 2007 (poster presentation).

Bustamante IV, Martins SS, Fiestas F, Ialongo N, Anthony JC. Problem behavior profile in subgroups of drug users. 69th College on Problems of Drug Dependence Annual meeting, CPDD, Quebec City, Canada, June 18 2007. Lobo DSS, Martins SS, Tavares H, Vallada H, Gentil V, Kennedy J. Personality profile and psychiatric co-morbidity discriminates pathological gamblers among same-sex sibling pairs. 2007 NIDA International Forum, Quebec City, Canada, June 18 2007 (oral presentation). Martins SS, Chilcoat HD. Factors associated with adolescent Ecstasy use in the National Survey of Parents and Youth. College on Problems of Drug Dependence 68th Annual Meeting, CPDD, Scottsdale, AZ, June 21st 2006 (poster presentation).

Gorelick DA, Martins SS, Copersino M, Soderstrom CA, Smith GS, Dischinger PC, McDuff DR, Hebel JR, Kerns TJ, Ho SM, Read KM. Risk of cannabis dependence in cannabis users among trauma inpatients. International Cannabinoid Research Society Annual Meeting, Lake Balaton, Hungary, June 25-28th 2006 (oral presentation).


Gorelick DA, Martins SS, Copersino M, Soderstrom CA, Smith GS, Dischinger PC, McDuff DR, Hebel JR, Kerns TJ, Ho SM, Read KM. Sociodemographic characteristics of substance users among trauma inpatients. American Psychiatric Association Annual Meeting, Toronto, Canada, May 24th 2006 (poster presentation).

Lobo DSS, Vallada HP, Knight J, Martins SS, Tavares H, Gentil V, Kennedy JL. Dopamine genes and pathological gambling in discordant sib-pairs. Society of Biological Psychiatry, 61st Annual Meeting,59:67s. Toronto, Canada, May 18th 2006 (poster presentation).

Martins SS, Ialongo N, Chilcoat HD. Gambling disorders among African-American adolescents: drug use and childhood vulnerability. National Conference of Responsible Gaming 6th Annual Conference on Gambling and Addiction, NCRG, Las Vegas, NV, December 7th 2005 (poster presentation).

Martins SS, Ialongo N, Chilcoat HD. Gambling disorders among African-American adolescents: drug use and childhood vulnerability. American Public Health Association, APHA, Philadelphia, PA, December 12th 2005 (poster presentation).

Martins SS, Ghandour L, Chilcoat HD. Past year analgesic dependence symptoms profile in different groups of past year analgesic users: a Generalized Estimating Equations approach. College on Problems of Drug Dependence, CPDD, Orlando, FL, June 21st 2005 (poster presentation).

Ghandour L, Martins SS, Chilcoat HD. Patterns and clustering of symptoms of analgesic dependence: a latent class approach. College on Problems of Drug Dependence, CPDD, Orlando, FL, June 21st 2005 (poster presentation).

Lobo DSS, Wilson D, Martins SS, Gentil V, Kennedy JL, Vallada HP. Impulsivity in Pathological Gamblers, no association with DRD5. XIIth World Congress for Psychiatric Genetics, WCPG, Dublin, Ireland, 9-13th October 2004. Am J Med Genetics Part B: Neuropsychiatric Genetics 2004; 130B (1): 118. (poster presentation).

Lobo DSS, Martins SS, Miguita K, Knight J, Gentil V, Vallada HP. Reward Mechanisms in Pathological Gambling and Genes Involved in Dopamine Transmission. World Congress of Psychiatric Genetics, WCPG, Dublin, Ireland, 9-13th October 2004 Am J Med Genetics Part B: Neuropsychiatric Genetics 2004; 130B (1): 119. (poster presentation).

Martins SS, Mazzotti G, Chilcoat HD. Ecstasy use in USA and its relationship with other drug use and dependence. In: American Psychiatric Association Annual Meeting, New York, May 3rd 2004 (poster presentation).

Martins SS, Lobo DSS, Tavares H, Gentil V. Female Pathological gambling: clinical and personality features. In: ASAM 35th Annual Scientific-Medical Conference. Washington, DC, April 2004 (poster presentation).

Martins SS, Mazzotti G, Chilcoat HD. Ecstasy use in USA from 1995 to 2001: comparison with marijuana users and association with other drug use. In: American Psychopathological Association, 94th Annual Meeting, March 2004 (poster presentation).

Tavares H, Martins SS, Zilberman ML, el-Guebaly N. Gamblers and treatment-seeking: why haven’t they come earlier? In: World Forum Drugs-Dependencies: Impacts and Responses, Montreal, September 2002.


Martins SS, Tavares H, Gentil V, Lobo DS, Galleti AM: Pathological gambling, gender, and risk-taking behavior in a Brazilian setting. In: American Psychiatric Association Annual Meeting, Philadelphia, May 2002.

Lobo DSS, Martins SS, Tavares H, Galleti AM, Gentil V: Personality and pathological gambling: a sibling pair analysis. In: American Psychiatric Association Annual Meeting, Philadelphia, May 2002.

Martins SS. Jogo patológico em mulheres. “Pathological gambling in women”, In: XIX Brazilian Congress of Psychiatry, Recife, October 2002. (oral presentation).

Martins SS, Caetano SC, Tavares H, Fuentes D: Personality characteristics of Female Pathological Gamblers. In: American Psychiatric Association Annual Meeting, New Orleans, May 2001.

Caetano SC, Lobo DSS, Michelon L, Spanghero MS, Martins SS. TOC na gravidez e lactação: relato de caso. "OCD during pregnancy and lactation”: a case report", In: Poster Session, XVIII Brazilian Congress of Psychiatry, Rio de Janeiro, 2000.

Lobo DSS, Caetano SC, Martins SS, Michelon L, Spanghero MS. Epilepsia de lobo temporal, agressividade e psicose afetiva - relato de caso. “Temporal epilepsy, aggressiveness and affective psychosis - a case report", In: Poster Session, XVIII Brazilian Congress of Psychiatry, Rio de Janeiro, 2000.

Spanghero MS, Lobo DSS, Michelon L, Martins SS, Caetano SC. Esquizofrenia refratária ao tratamento: associação de clozapina e lítio- relato de caso. “Refractory schizophrenia: association of clozapine with lithium - a case report", In: Poster Session, XVIII Brazilian Congress of Psychiatry, Rio de Janeiro, 2000.

Michelon L, Caetano SC, Lobo DSS, Martins SS, Spanghero MS. Koro-síndrome ligada à cultura? relato de caso. "Koro-syndrome is it linked to culture? a case report", In: Poster Session, XVIII Brazilian Congress of Psychiatry, Rio de Janeiro, 2000.

Martins SS, Caetano SC, Spanghero MS, Lobo, DSS, Michelon L. Manejo terapêutico do transtorno obsessivo-compulsivo - um relato de caso. "Therapeutic management of obsessive-compulsive disorder - a case report", In: Poster Session, XVIII Brazilian Congress of Psychiatry, Rio de Janeiro, 2000.

Spanghero MS, Caetano SC, Martins SS, Michelon L, Lobo DSS. Relato de caso: neurossífilis, um modelo de síndrome neuropsiquiátrica. “Case report: neurosyphilis, a neuropsychiatric syndrome", In: Poster Session, XVIII Brazilian Congress of Psychiatry, Rio de Janeiro, 2000.

Martins SS, Caetano SC, Lobo DSS, Michelon L, Spanghero MS. Sintomas depressivos precedendo doença de alzheimer “Depressive symptoms preceding Alzheimer disease”. In: Poster Session, XVIII Brazilian Congress of Psychiatry, Rio de Janeiro, 2000.

Caetano SC, Meleiro AMAS, Lobo DSS, Michelon L, Villanacci RAF, Martins SS. Associação de sintomas esquizofrênicos e hipertiroidismo por Doença de Graves: relato de caso. “Association between schizophreniform symptoms and Graves disease: case report”, In: Poster Session, XVII Brazilian Congress of Psychiatry, Fortaleza, 1999.


Lobo DSS, Caetano SC, Michelon L, Martins SS, Villanacci RAF. Esquizofrenia e anorexia nervosa no sexo masculino “Schizophrenia and anorexia nervosa in male gender: case report”, In: Poster Session, XVII Brazilian Congress of Psychiatry, Fortaleza, 1999.

Martins, SS, Meleiro AMAS, Lobo DSS, Michelon L, Caetano SC, Villanacci RAF. Impulsividade em militares: a importância de um diagnóstico precoce - um relato de caso “Impulsivity in the military: the importance of diagnosis: case report”, In: Poster Session, XVII Brazilian Congress of Psychiatry, Fortaleza, 1999.

Michelon L, Caetano SC, Meleiro AMAS, Lobo DSS, Martins SS, Villanacci, RAF. Exposição ocupacional a substâncias neurotóxicas e sintomas psiquiátricos: relato de caso "Occupational exposure to neurotoxic substances and development of psychiatric symptoms: case report”, In: Poster Session, II International Symposium on Secondary Depression, São Paulo, 1999.

Martins SS, Lobo, DSS, Michelon, L, Caetano, SC. Fatores hormonais e terapêutica da depressão pós-parto: uma revisão. ” Hormonal factors and therapy of post-partum depression: a review”, In: Poster Session, II International Symposium on Secondary Depression, São Paulo, 1999.

Caetano, SC, Lobo DSS, Martins SS, Michelon, L. O uso de antidepressivos no ciclo gravídico-puerperal. “Antidepressants in pregnancy and puerperium”, In: Poster Session, II International Symposium on Secondary Depression, São Paulo, 1999.

ADDITIONAL INFORMATION

Personal statement of research and research objectives

My current research interests focus on the epidemiology of drug use disorders and in the association of drug use disorders with psychiatric comorbidity. I am particularly interested on the epidemiology of ecstasy use/club drugs among adolescents and young adults, on the epidemiology of extramedical opioid analgesic use and prescription drug use and on the epidemiology of gambling and pathological gambling among adolescents and adults. I am also interested in gender differences in gambling/pathological gambling and in substance use disorders, in risk and protective factors for drug abuse/dependence and gambling/pathological gambling, in drug use, gambling and mental health problems among minorities/underserved populations as well as in preventive interventions in drug use/misuse and gambling/pathological gambling. In those capacities, I have applied Biostatistics methods (such as Survival Analysis- Cox proportional hazard models with time-dependent covariates, Generalized Estimating Equations, Latent Class Analysis and Growth Mixture models) to address my research interests.

Keywords

Drug Abuse Epidemiology, Adolescence, Epidemiology of Club Drugs, Epidemiology of extramedical prescription drug use, Epidemiology of opioid analgesics, Epidemiology of gambling and pathological gambling, adolescent gambling, gender differences in gambling. Statistical knowledge Able to use SPSS, Stata and M-Plus. Attended courses on Psychosocial Methods for Research, Longitudinal Data Analysis, and Survival Analysis during post-doctoral training at JHSPH.


Participation in Summer Courses/ Workshops Attended course: National Household Survey on Drug Abuse: Advanced Data Analysis. Department of Mental Health Summer Institute, JHSPH. June 25-28, 2004. Attended course: Longitudinal Analysis with Latent Variables. Department of Mental Health Summer Institute, JHSPH. July 5-10, 2006.

Attended course: Workshop on Statistical Analysis with Latent Variables Using Mplus- Continuous Variables, JHSPH, October 19-20, 2006. Attended course: Workshop on Statistical Analysis with Latent Variables Using Mplus- Categorical Variables, JHSPH, March 13-14, 2007. Attended course: SS/R: Estimating the Effects of Mental Health Interventions in Non-Experimental Settings, JHSPH, July 12-13, 2007. Attended course: Workshop on Statistical Analysis with Latent Variables Using Mplus- Multilevel Modeling, JHSPH, August 21-22, 2007. Attended conference: Addiction, Infection Diseases and Public Health, 2nd Annual Conference, JHSPH, April 21, 2008. Attended conference: Addiction, Infection Diseases and Public Health, 3rd Annual Conference, JHSPH, April 24, 2009. Languages Portuguese (Native speaker) English (Fluent written & spoken) French (Intermediate written and spoken) Spanish (Basic written and spoken)

silvia s. martins, md, phd up to 2010...silvia s. martins, md, phd curriculum vitae (10/2009) silvia...

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