seminar asthma.pdf

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    Airway inflammation

    Bronchial

    hyperresponsiveness

    Intermittent airflow

    obstruction

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    Intermittent symptomatic episodes of:

    Coughing (day, night, or with exercise)

    Difficulty breathing/Shortness of breath

    Wheezing (a whistling noise)

    Chest tightness

    Trouble sleeping/ waking at night

    May be asymptomatic between attacks

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    Inspection:- shape: hyperinflated insevere asthma

    - movement of chest/silentchest (life-threatening)

    - chest deformity:

    - recession:

    Palpation:

    - chest expension may be

    reduce (hyperinflated)/normal

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    24/39 Global Initiative for Asthma

    GINA assessment of symptom control

    A. Symptom control

    In the past 4 weeks, has the patient had:Well-

    controlledPartly

    controlledUncontrolled

    Daytime asthma symptoms morethan twice a week?

    Yes No

    None ofthese

    1-2 ofthese

    3-4 ofthese

    Any night waking due to asthma?

    Yes No

    Reliever needed for symptoms*more than twice a week?

    Yes No

    Any activity limitation due to asthma?

    Yes No

    B. Risk factors for poor asthma outcomes

    Assess risk factors at diagnosis and periodically Measure FEV at start of treatment, after 3 to 6 months of treatment to record the atients!"#$ &'() *+, &-&* (/0

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    25/39 Global Initiative for Asthma

    Assessment of risk factors for poor asthma

    outcomes

    GINA 2015 Box 2-2B 4/4

    Risk factors for exacerbations include: Ever intubated for asthma

    Uncontrolled asthma symptoms

    Having !1 exacerbation in last 12 months

    Low FEV1(measure lung function at start of treatment, at 3-6 monthsto assess personal best, and periodically thereafter)

    Incorrect inhaler technique and/or poor adherence

    Smoking

    Obesity, pregnancy, blood eosinophilia

    Risk factors for fixed airflow limitation include:

    No ICS treatment, smoking, occupational exposure, mucushypersecretion, blood eosinophilia

    Risk factors for medication side-effects include:

    Frequent oral steroids, high dose/potent ICS, P450 inhibitors

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    Global Initiative for Asthma

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    Global Initiative for Asthma

    " How often should asthma be reviewed?

    #

    1-3 months after treatment started, then every 3-12 months

    # During pregnancy, every 4-6 weeks

    # After an exacerbation, within 1 week

    " Stepping up asthma treatment

    #

    Sustained step-up, for at least 2-3 months if asthma poorlycontrolled

    # Short-term step-up, for 1-2 weeks, e.g. with viral infection or

    allergen

    # Day-to-day adjustment

    "

    Stepping down asthma treatment

    # Consider step-down after good control maintained for 3 months

    # Find each patients minimum effective dose, that controls both

    symptoms and exacerbations

    Reviewing response and adjusting treatment

    GINA 2015

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    " Avoidance of tobacco smoke exposure

    " Encourage physical activity

    " Occupational asthma

    # Ask patients with adult-onset asthma about work history. Remove

    sensitizers as soon as possible.

    "

    Avoid medications that may worsen asthma

    # Always ask about asthma before prescribing NSAIDs or beta-

    blockers

    Non-pharmacological interventions