Q1-All proteins contain theA- same 20 amino acids in different sequence and numberB-different amino acids C-300 amino acids occurring in natureD- only a few amino acids.

Q2-Protein containA-only L-α-amino acidsB-only D-amino acidsC-DL-amino acidsD- both A and B

Q3-The optically inactive amino acid isA-glycineB-serine C-threonineD-valine

Q4-Sulpher containing amino acid isA-methionineB-leucineC-valineD-aspargine

Q5-An aromatic amino acid is A-cysteineB-arginineC-tyrosineD-taurine

Q6-An amino acid not found in proteins isA- β alanineB-lycine C-glycineD-arginine

Q7-Pepsinogen is converted to active pepsin byA-HClB-Ca ionsC-bile acidsD-entrokinase

Q8-The main sites for oxidative deamination areA-liver and kidneyB-skin and pancreasC-intestine and kidneyD-liver and spleen

Q9-A positive nitrogen balance occursA-in growing infantB-Following surgeryC-in advanced cancerD-in Kwashiowkor

Q10-The main sites of urea synthesis is A-liverB-kidneyC-skinD- intestine

Q11-The enzymes of urea synthesis are found inA-mitochondria onlyB-cytosol onlyC-both mitochondria and cytosolD-nucleus

Q12-The number of ATP required for urea synthesis is

A-0B-1C-3D-2

Q13-In urea synthesis, the amino acid functioning solely as an enzyme activator:

A-N-acetyl glutamateB-ornithineC-citrullineD-arginine

Q14-The enzyme carbamoyl phosphate synthetase requires

A-Mg ionB-Ca ionC-Na ionD-K ion

Q15-A compound serving a link between citric acid cycle and urea cycle is

A-malateB-citrateC-fumarateD-succinate

Q16-The 2 nitrogen atoms in urea are contributed by

A-ammonia and glutamateB- glutamate and glutamineC-ammonia and aspartateD-ammonia and alanine

Q17-Tryptophan could be considered as precursor of

A- serotoninB-thyroid hormonesC-histamineD-tyrosine

Q18-The amino acid which detoxicated benzoic acid to form hippuric acid is

A-glycineB-arginineC-alanineD-aspartic acid

Q19-The amino acids involved in the synthesis of creatine are

A-arginine, glycine, and methionineB-alanine, glycine, and methionineC-arginine, alanine, and methionineD- arginine, alanine, and glycine

20-Two amino groups are present in A-leucine B-lycine C-isoleucineD-proline

Q21-All the following are branched amino acids except

A-valineB-leucineC-isoleucineD-lycine

Q22-Alanine can be synthesized from a-glutamate and α-ketogltarateB-pyruvate and α-ketogltarateC-pyruvate and glutamateD-aspartate and α-ketogltarate

Q23-All the following are required for synthesis of aspartate except

A- oxalo acetateB- α-keto glutarateC-glutamateD-pyridoxal phosphate

Q24-All the following are required for synthesis of glutamine except

A-glutamateB-ammoniaC-pyridoxal phosphateD-ATP

Q25-Non protein amino acids areA-ornithineB-β alanineC-γ-amino butric acidD- all of these

Q26-An organ which is extremely sensitive to ammonia toxicity is

A-liverB-brainC-kidneyD-heart

Q27-The major site of urea synthesis isA-liverB-brainC-kidneyD-heart

Q28-Carbamoyl phosphate required for urea synthesis is formed in

A- cytosolB-mitochondriaC-both A and BD-non of A and B

29-The following enzyme of urea cycle is present in cytosol:

A-argenino succinic acid synthetaseB-argininosuccinaseC-both A and BD- neither A nor B

Q30-ATP is required in the following reactions of urea cycle.A-synthesis of carbamoyl phosphate and

citrulline.B-synthesis of citrullin and arginino succinateC-synthesis of argininosuccinate and arginineD-synthesis of carbamoyl phosphate and

argininosuccinate.

Q31-Histamine is formed from histidine byA-deaminationB-dehydrogenationC-decarboxylation D-carboxylation

Q32-In metabolic point of view, amino acids are classified as

A- glycoigenicB-ketogenicC-glycogenic or ketogenicD- All of these

Q33-A ziwitter ion isA-positive ionB-negative ion C-both A and BD- Non of these

Q34- The amino acid which contain guanidine group is

A-histidineB-arginineC-citrullinD-ornithine

Q35-The amino acid which contain an indol group is

A-histidineB-arginineC-glycineD-tryptophan

Q36-Which among the following has an imidazole group?

A-histidineB-tryptophanC-prolineD-hydroxy proline

Q37-Branched chain amino acids areA-cysteine and cystineB-tyrosine and tryptophanC-glycine and serineD-valine and leucine

Q38-The amino acid containing hydoxyl group:A-alanineB-isoleucineC-arginineD-threonine

Q39-The basic amino acidA-glycineB-histidineC-leucineD-proline

Q40-The amino acid which synthesizes many hormones:

A-valineB-leucineC-phenyl alanineD-histidine

Q41-An amino acid not involved in urea cycle isA-ornithineB-citrullineC-arginineD-alanine

Q42-In humans NH2 is detoxified in liver asA-ureaB-creatinineC-uric acidD-uronic acid

Q43-Two nitrogen atoms of urea in the urea cycle come from

A-NH3

B-one from NH3 and one from aspartatec-one from NH3 and one from glutamated-one from NH3 and one from alanine

Q44-Pyruvic acid can be obtained by transamination of alanine withA-α keto glutarateB-aceto acetic acidC-β hydroxy butric acidD-phosphoenol pyruvic acid

Q45-Zymogen isA-an intracellular enzymeB-serum enzymeC-a complete extracellular enzymeD-an inactivated enzyme

Q46-Along withCO2, NH3, and ATP, the amino acid that is needed in urea cycle isA-alanineB-aspartateC-isoleucineD-glycine

Q47-The transaminase activity needs the coenzyme

A-ATPB-FADC-NADD-B6-PO4

Q48-Transamination is a A-Irreversible processB-Reversible processC-Both [A] and [B]D-None of these

Q49-synthesis of glutamine is accompanied by the hydrolysis ofA-ATPB-ADPC-TPPD-Creatine phosphate

Q50-Glutathione isA-dipeptideB-tripeptideC-polypeptideD-none of these

Q51-Number of chains in globin part of normal Hb:A-1B-2C-3D-4

Q52-Oxaloacetate is converted to aspartate byA-reductaseB-oxidaseC-transaminaseD-catalase

Q53-Which of amino acid produces a vasodilator on decarboxylation?A-glutamic acidB-histidineC-ornithineD-cysteine

Q54-The amino acid which synthesis many hormones

A-valineB-alanineC-pheyl alanineD-aspartic acid

Q55-Which bond is present in the primary structure of protein?A-hydrogen bondB-ester bondC-peptide bondD-Ionic bond

Q56-An essential amino acid in man isA-prolineB-threonineC-aspargineD-tyrosine

Q57-An example of polar amino acid isA-AlanineB-LeucineC-ArginineD-Valine

Q58-All the following statements about albinism are correct except A-Tyrosine hydroxylase is absent or deficient in melanocytes. B-Skin is hypopigmented C-It results in mental retardation D-Eyes are hypopigmented

Q59-Glycine is not required for the formation of A-Toucholic acid B-Creatine C-Purines D-Pyrimidines

Q60-Clinical features of Kwashiorkor include all of the following except A-Mental retardation B-Muscle wasting C-Oedema D-Anemia

Q61-Serotonin is synthesized from A-Serine B-Phenylalanine C-Tyrosine D-Tryptophan

Q62-Synthesis of glutamine is accompanied by by the hydrolysis of A-ATP B-ADP C-TPP D-Creatin phosphate

Q63-Accumulation of tryptophan in blood is known as:

A-Pompes disease B-Wilsons disease C-Wolmans disease D-Hartnups disease