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Page 1: Scientific program

SCIENTIFIC PROGRAM

THEMATIC POSTER SESSION SATURDAY, MARCH 16, 1996

12:00 PM TO 4:00 PM

ALLIED HEALTH PROFESSIONALS

PEFR as a Measure of Airway Obstruction in Pediatric Asthmatic Patients Arant CB BS, Baker RR PhD, Rupp NT MD, Augusta, GA

2 Questionnaire, BHR, and Total IgE Variability Over Time and Their Interrelationships Drury DARN, Daniels L MA, Blumenthal MN MD, Minneapolis, MN

The Role of a Peripatetic Allergy Nurse Practitioner in the Care of the Allergic Patient Within Primary Care Brydon MJ RGN OHNC, Norwich, United Kingdom

4 Office Nurses' Perceptions of Competencies for the Patient Teaching Role Wagner CW MSN RN PNP, Houston, TX

Starting a Database in Clinical Practice: Benefits of Even Simple Electronic Records in the Organization of an Immunization Clinic Veltri N RN, Brooks J RN, Bell S, George J, Rios-Rodriguez A, Engler RJM MD, Washington, DC

6 Interrelationship of an Asthma Respiratory Questionnaire, ISAAC Video Questionnaire, and Bronchial Hyperresponsiveness/Reversibility Stockton M MA, Friedhoff L MS, Barnes K PhD, Togias A MD, Rosenthal R MD, Malveaux F MD, Marsh D PhD, Baltimore, MD; Washington, DC

Comparison of the Efficiency of Two Nebulizer Systems Using Battery Power Loffert DT MA, Richmond, VA

Ethnic Differences in Biologic Factors Related to Childhood Asthma Joseph CLM, Ownby DR, Tilley BC, Detroit, MI

Awareness of Potential Adverse Reactions to Triatoma Bite and Appropriate Treatment Johnson SF RN, Zeiger RS MD PhD, Marshall NA PhD, San Diego, CA

10 An Intervention Program Prolongs Duration of Breast Feeding of Newborns at High Risk for Development of Asthma and Allergies Lilley MK RN, Harrison SE RN BN, Winnipeg, Canada

11 Community-Based Asthma Education Project for Latino Children Gorham NF, Santoyo D, Gruchalla RS MD PhD, Dallas, TX

12 A Comparison Study of Candida Albicans and Dermatophyton "0" Skin Test Antigens Gerard AM RN, Roth RM MD, Garden Grove, CA

13 Evaluation of Low Allergenic Latex Gloves in Latex Sensitive Patients Gehring LL MS RNCS, Fink JN MD, Kelly KJ MD, Milwaukee, WI

440 January 1996 J ALLERGY CLIN IMMUNOL

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J ALLERGY CLIN IMMUNOL Program 441 VOLUME 97, NUMBER 1, PART 3

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Monitoring of Indoor Temperature and Relative Humidity in the Summertime in Homes in the Southeastern US Ford JL MT, Rupp NT MD, Augusta, GA

Value of Peak Flow Readings in the Safe Administration of Immunotherapy in Asthmatics Dunn JM RN, DeMasi JM MD, Albany, NY

Success Rate in Changing Patients on Intravenous Gammaglobulin (IVG) to a Solvent Detergent Treated Product (SDTP) Dirato C RN, Stein MR MD, Amran D MD, North Palm Beach, FL

The High Risk Asthma Program Conboy KA MS RN PNP, Schneider LC MD, Boston, MA

Immunotherapy Vial Preparation Using a Computer Spreadsheet Coleman C RN, Windom H MD, Sarasota, FL

Comparison of Performance of Four Skin Test Devices Caruso KM RN BSN, Witkowski S LPN, Slattery SM RN ADN, Melton AL MD, Wagner WO MD, Pien LC MD, Cleveland, OH

Relationship Between Bronchodilatory Reversibility (REV), Bronchial Reactivity (BR), and Baseline Pulmonary Function in Asthma Brennan F BS, Horowitz E BA, Togias A MD, Baltimore, MD

Computerization of Extract Information in the Allergy Office Brazener L RN, Roth SL MD, Rochester, NY

Patient Education in a Managed Care Environment Brabyn L MA, Nisam M MD, Margolin A MD, Mill Valley, CA

Reliability of Instruments in a Pediatric Asthmatic Population Bagstad K MN RN CS, Lacey-Haun L RN PhD, Buford T RN MN, Kansas City, MO

Effects of Advertisement Methods on Success of Subject Recruitment for Clinical Research Trials Angelini BL RN BSN, Cordoro KM BS, Fireman P MD, Skoner DP MD, Pittsburgh, PA

DISEASES OF THE UPPER RESPIRATORY TRACT

25 Clinical Implications of Sinus Imaging in Pediatrics Kalman DD DO, Gross GW MD, McGeady SJ MD, Philadelphia, PA

26 Total IgE Levels (IgE) Correlate with the Severity of Sinusitis on Computerized Tomography (CT) Scans Suh SH MD, Baroody FM MD, Naclerio RM MD, Chicago, IL

27 Chronic Sinusitis in an Allergy Office McNally PA MD, White MV MD, Kaliner MA MD, Washington, D.C.

28 Determination of the Duration of Antibiotic Therapy in Chronic Sinusitis German D MD, Serwonska M MD, Strub M MD, San Francisco, CA

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Treatment of Chronic Sinusitis in an Allergy Office Kaliner MA MD, McNally PA MD, White MV MD, Washington, DC

J ALLERGY CLIN IMMUNOL JANUARY 1996

30 CT Sinus Studies in Allergic Rhinitis Leipzig JR MD, Martin DS MD, Slavin RG MD, St. Louis, MO

31 Clinical and Immunologic Characteristics of Patients with Allergic Fungal Sinusitis Chrzanowski RR MD, Rupp NT MD, Kuhn FA MD, Dolen WK MD, Augusta, GA

32 Immunologic Changes in Patients with "Allergic Mucin" Quintal MC MD, Ostro MG MD, Bornschein S MD, Salman S MD, Bloch KJ MD, Boston, MA

33 A Subtype of Allergic Fungal Sinusitis (AFS) with Laboratory Findings Similar to Allergic Bronchopulmonary Aspergillosis (ABPA) Rubinstein S MD, Sunnyvale, CA

34 Concomitant Sinus Mycetoma and Allergic Fungal Sinusitis Soto-Aguilar M, deShazo R, O'Brien M, Chapin K, Blunck C, Lyons M, Swain R, Mobile, AL

35 Endothelial VCAM-1 Expression is Increased in Nonallergic Chronic Hyperplastic Sinusitis with Nasal Polyposis (CHS/NP) Hamilos DL, Leung DYM, Wood R, Cunningham L, Bean DK, Song YL, Schotman E, Hamid Q, St. Louis, MO," Denver, CO," Montreal, Quebec, Canada

36 Fluticasone Aqueous Nasal Spray in the Treatment of Nasal Polyposis Juliusson S MD, Holmberg K MD PhD, Balder B BS, Smith DL BS, Karlsson G MD PhD, Gothenburg, Sweden; Greenford, United Kingdom

37 Development and Validation of a Nasal Polyposis Quality of Life Questionnaire Keith PK MD, Conway M RN, Dolovich J MD, Hamilton, Canada

38 Cytokine Gene Expression in Nasal Polyp Lee CH MD, Rhee CS MD, Min YG MD, Seoul, Korea

39 Messenger RNA Expression of RANTES, Interleukins 6 and 12 in Nasal Polyps in Relation to Allergy Davidsson A MD, Hellquist HB MD PhD, Danielsen A MD, Viale G MD, ft'rebro, Link6ping, Sweden; Bergen, Norway; Milan, Italy

40 IL-5 Dominates in Nasal Polyps Rudack C MD, Reeker HC MD, Wagenmann M MD, Bachert C MD, Di~sseldorf, Germany

41 Peptide Absorption Across the Airway Mucosa in Seasonal and Perennial Allergic Rhinitis Greiff L, Andersson M, Svennson C, Wollmer P, Lundin S, Persson CGA, Lund, Sweden

42 Correlation Between Eosinophil Cationic Protein (ECP) and Eosinophil Peroxidase (EPO) in Rhinitis Ostertag P MD, Rasp G MD, Enander I PhD, Munich, Germany; Uppsala, Sweden

43 Increases in RANTES mRNA and Protein in the Nasal Mucosa and Nasal Secretions in Hay Fever Patients After Allergen Challenge Rajakulasingam K MD, Hamid Q PhD, O'Brien F BSc, Schotman E, Jose PJ PhD, Williams TJ MD, Jacobson M PhD, Barkans J BSc, Durham SR MD, London, United Kingdom; Montreal, Canada

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J ALLERGY CLIN IMMUNOL P r o g r a m 443 VOLUME 97, NUMBER 1, PART 3

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Nasal Provocation with Cockroach (CR) Extract Hernandez LS MD, Fernhndez-Caldas E PhD, Lockey RF, Tampa, FL

Recruitment of FceRI Positive Cells in the Nasal Mucosa in Atopic Rhinitic Subjects Following Allergen Challenge O'Brien F BSc, Rajakulasingam K MD, Durham SR MD, Humbert M MD, Taborda-Barata L MD, Kay AB MD, Grant JA MD, London, United Kingdom; Galveston, TX

Expression of IL-13 in Allergen-Induced Late Nasal Reaction and in Response to Topical Steroids Ghaffar O, Durham S, Laberge S, Jacobson M, Rak S, Lowhagen O, Hamid Q, London, United Kingdom; Gothenburg, Sweden; Montreal, Canada

Nasal Airway Changes Assessed by Acoustic Rhinometry and Mediator Release During Immediate and Late Reactions to Allergen Challenge Getsy J DO, Zweiman B MD, Lane A MD, Kalenian M MD, Dory R PhD, Lanza D MD, Philadelphia, PA

Repeated Nasal Challenges with Allergen Produce Exudative Hyperresponsiveness and Local Eosinophilia Andersson M, Svensson C, Greiff L, Linden M, Persson CGA, Lund, Sweden

Tryptase Release After Nasal Provocation Test in Parietaria Allergy Palma-Carlos ML PharmD PhD, Santos MC PharmD PhD, Pedro E MD, Spinola A MD, Ferreira F MD, Palma-Carlos AG MD PhD, Lisbon, Portugal

Effects of Exogenous Neuropeptide Y on Nasal Response to Allergen Challenge in Atopic Patients Mosimann BL MD, Lacroix JS MD, Lausanne, Geneva, Switzerland

Children With Allergic Rhinitis Have Low Mucosal IgA, A Longitudinal Cohort Study Ludviksson BR MD, Thorarensen O, Ardal B MD, Valdimarsson H MD FRC Path, Reykjavik, Iceland

Differences in Mite-Specific Immune Responses in Atopic Patients with Asthma or Rhinitis Sherman MB MD, Chen K, Fogelman D, Liao Z MD, Chen Y, Rosenstreich DL MD, Bronx, NY

Development of a Dose-Response Protocol for Localized Nasal Provocation with Capsaicin (CAP) Togias A MD, Lai G BS, Baltimore, MD

Reproducibility of a Nasal Allergen Challenge Model in Evaluating the Efficacy of Intranasal Beclomethasone (BEC) Proud D PhD, King EC PhD, Riker DK PhD, Togias A MD, Baltimore, MD; CincinnatL OH

The Effect of Prior Exposure for 6 Hours to 400ppb NO 2 on Allergen-Induced Inflammatory Changes in Nasal Airways of Allergic Rhinitics and the Influence of Fluticasone Propionate Aqueous Nasal Spray (FP) Wang JH MD, Devalia JL PhD, Rusznak C MD, Bagnall A BSc, Davies RJ FRCP, London, United Kingdom

Effects of Nedocromil Sodium (NDS) on the Late Nasal Response to Allergen Challenge (LNR) and the Accompanying Cellular Changes in the Nasal Secretions (NS) Pelikan Z MD PhD, Pelikan-Filipek M MD, Stegt BSV, Breda, The Netherlands

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444 Program J ALLERGY CLIN IMMUNOL JANUARY 1996

57 The Protective Effects of Intranasal Nedocromil Sodium (NDS) on the Immediate (1NR) and the Late Nasal Response (LNR) to Allergen Challenge Pelikan-Filipek M MD, Oostenbrink JH MD, Pelikan Z MD, Breda, The Netherlands

58 Improved Protection from Topical Levocabastine over Nedocromil Sodium in Conjunctival Provocation Test with Allergen: A Double-Blind, Cross-over Study Hammann C MD, Kammerer R MD, Gerber M MSc, Spertini F MD, Lausanne, Switzerland

59 Pharmacoeconomic Benefits of Fluticasone Propionate Aqueous Nasal Spray 200 ug Once Daily in Perennial Allergic Rhinitis Adams JE MMath, Blackman NJM MSc, Tesarowski DB PhD, Stepner N MHSc, Mississauga, Ontario, Canada

60 Efficacy and Safety of Once-Daily Triamcinolone Acetonide Aqueous Nasal Spray in Pediatric Patients with Spring Grass Seasonal Allergic Rhinitis Smith JA MD, Schenkel EJ MD, Gross G MD, Jacobson K MD, Kobayashi R MD, Settipane G MD, Feiss G MS, Furst JA BS, Simpson B BS, Providence, RI," Easton, Collegeville, PA; Dallas, TX; Eugene, OR; Omaha, NE

61 Triamcinolone Acetonide Aqueous Nasal Spray Does Not Alter Adrenocortical Function in Children with Allergic Rhinitis Schenkel EJ MD, Ellis MH MD, Gross G MD, Lanier B MD, Mendelson L MD, Nayak A MD, Feiss G MS, Furst JA BS, Simpson B BS, Smith JA MD, Easton, PA; Dallas, Fort Worth, TX; West Hartford, CT; Normal, IL; Collegeville, PA

62 Lack of Systemic Activity with Intranasal Mometasone Furoate Seiberling M MD, Cutler DL MD, Cuss FM MD, Affrime MB PharmD, Brannan MD PhD, Kenilworth, N J," Freiburg, Germany

63 Intranasal Fluticasone Propionate (FP) is More Effective than Loratadine (LOR) for Treatment of Seasonal Allergic Rhinitis Symptoms Nayak AS MD, Shulan D MD, Bernstein DI MD, Livezey M MD, Settipane G MD, Chervinsky P MD, Melamed J MD, Selcow J MD, Reed KD BS, Anschuetz G MS, Cook CK MS, Rogenes PR PhD, Normal, 1L; RTP, NC

64 Once Daily Mometasone Furoate Aqueous Nasal Spray is as Active as Twice Daily Beclomethasone Dipropionate for Perennial Allergic Rhinitis Drouin M MD, Nolop K MD, Lutsky B PhD, 192-293 Study Group, Ottawa, Ontario, Canada; Kenilworth, NJ

65 Pseudoephedrine (PDE) Pharmacokinetics and Pharmacodynamics in Children with Allergic Rhinitis Gu X PhD, Simons KJ PhD FRCPC, St. Vincent JCM BN, Watson WTA MD, Reggin JD MD, Simons FER MD, Winnipeg, Canada

66 Phenylpropanolamine (PPA) Pharmacokinetics and Pharmacodynamics in Children with Allergic Rhinitis St Vincent JCM BN, Simons KJ PhD, Gu X PhD, Watson WTA MD, Reggin JD MD, Simons FER MD, Winnipeg, Canada

67 Recombinant Human Monoclonal Anti-IgE Therapy in Allergic Rhinitis Casale TB MD, Bernstein IL MD, Busse WW MD, LaForce CF MD, Tinkelman DG MD, Stoltz RR MD, Dockhorn RJ MD, Adelman DC MD, Iowa City, 1A; Cincinnati, OH; Madison, WI," Raleigh, NC; Atlanta, GA; Evansville, IN; Lenexa, KS," San Francisco, CA

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J ALLERGY CLIN IMMUNOL Program 445 VOLUME 97, NUMBER 1, PART 3

68 N-Acetyl-Aspartyl-Glutamic Acid Inhibits Late Antigen-Induced Reaction in the Nose Miadonna A MD, Cottini M MD, Lorini M MTech, Candiani C MD, Tedeschi A MD, Milazzo N MD, Milano, Saronno, Bergamo, Italy

69 The Effects of Salmeterol on the Early and Late Sequelae of Allergen Challenge in the Nose Gerth van Wijk R, de Graaf-in'tVeld C, Tak C JAM, Garrelds IM, van Toorenenbergen AW, Rotterdam, The Netherlands

70 Immediate and Short-Term Effects of Benzalkonium Chloride on Nasal Mucosa McMahon C, Ryan R, Darby YC, Scadding GK, London, United Kingdom

OCCUPATIONAL ASTHMA

71 Occupational Asthma Caused by Roasted Coffee: Immunological Evidence that Roasted Coffee Contains the Same Antigens as Green Coffee, but Fewer L'Archev~que J RT, Lemi6re C MD, Malo JL MD, McCants M RT, Lehrer S PhD, Montreal Canada; New Orleans, LA

72 Closed-Circuit Apparatus for Specific Inhalation Challenges with Occupational Agents in Vapour Form: Application to Formaldehyde Cloutier Y Ing, Perrault G PhD, Drolet D RT, Cartier A MD, Lemi6re C MD, Malo JL MD, Montreal, Canada

73 Isolated Late Asthmatic Reaction After Exposure to a High-Molecular-Weight Occupational Agent Cartier A MD, Lemi6re C MD, Malo JL MD, Montreal Canada

74 Occupational Asthma to Lobster and Shrimp Vall6e J RT, Desjardins A MD, Lemi6re C MD, Lehrer S PhD, Malo JL MD, Montreal, Canada; New Orleans, LA

75 Allergen Cross-Reactivity Between a-Amylase (Aspergillus Oryzae), Hemicellulase (A. niger) and Amyloglycosidase (A. niger) Wiewrodt R MD, Spix K, Biller U, Viel K, Bargon J, Caspary W, Buhl R, Frankfurt, Main, Germany

76 Inhalative and Ingestive Occupational Allergy to Boletus edulis Torricelli R MD, Wtithrich B MD, Zi~rich, Switzerland

77 Comparative Study to Low Persistent vs High Short Exposition to TDI in Two Different Populations Gagliardi JR MD, Castro CC MD, Soriano L MD, Vila O MD, Lerda D PhD, Romero M PhD, Muifio JC MD, Cordoba, La Rioja, Marcos duarez, Argentina

78 Diesel Exhaust Particles and Phenanthrene Enhance IgE Production by Human B Cells In Vitro Tsien A MD, Diaz-Sanchez D PhD, Ma J BS, Saxon A MD, Los Angeles, CA

79 Identification of Prolamin Allergens Involved in Cereal Hypersensitivity Sandiford CP BSc, Tatham A PhD, Jones MG PhD, Fido R PhD, Tee RD PhD, Shewry PR DSc FIBiol, Newman Taylor AJ FRCP FFOM, London, Bristol United Kingdom

80 Long-Term Treatment of Occupational Asthma: A Follow-up Study Siracusa A MD, Marabini A MD, Ripandelli A MD, Truppe S MD, Perugia, Italy

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446 D .~.rourom J ALLERGY CLIN IMMUNOL JANUARY 1996

81 Alveolar Macrophage Heterogeneity in Hypersensitivity Pneumonitis Delgado L MD, Winck JC MD, Rodrigues J MD, Ramos JP MD, Fleming Torrinha JA PhD, Porto, Portugal

82 Bronchial Hyperreactivity Among Cotton Textile Workers Torres da Costa J, Silva JP, Barros H, Azevedo M, Porto, Portugal

83 Underutilization of Respiratory Measurements in Evaluations of Suspected Occupational Asthma Dykewicz MS MD, St. Louis, MO

84 Formaldehyde and Phenol Exposure During the Anatomy Dissecting Course: A Possible Source for IgE-Mediated Sensitization? Tschabitscher M, Wantke F, Focke M, Hemmer W, Gann M, Tappler P, Bracun R, Wolf S, GOtz M, Jarisch R, Vienna, Europe

85 In Vivo and In Vitro Activites of Purified Allergens from Rye Flour Armentia A, Garcia-Casado G, S~inchez-Monge R, Salcedo G, Madrid, Spain

86 Documentation of Nasal Irritant Sensitivity Utilizing Pulsed Carbon Dioxide Stimuli Shusterman D MD MPH, Balmes J MD, San Francisco, CA

87 Occupational Asthma to Aromatic Herbs Patry N RT, Malo JL MD, Lemi~re C MD, Cartier A MD, Montreal, Canada

88 Chloramine-T Induced Asthma in a Female Cleaner Kujala VM MD, Reijula KE MD PhD, Oulu, Finland

89 Following-Up of 91 Patients with Occupational Asthma (OA) Echechipia S, Garcia BE, Alvarez MJ, Acero S, Olaguibel JM, Rodriguez A, Lizaso MT, Tabar AI, Pamplona, Spain

90 The Lung B Lymphocyte (B Cell) Antibody Response to Trimellitic Anhydride (TMA) Inhalation Zeiss CR MD, Siddiqui FS PhD, Garthwaite S BS, Henderson J, Levitz D BS, Hatoum NS PhD, Chicago, IL

91 Immune System Function in the Offspring of Methyl Mercury Exposed Rats Wild L MD, Ortega H MD, Salvaggio J MD, Lopez M MD, New Orleans, LA

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Specific Immunoglobulins to Soybean Hull Allergens in Soybean Asthma Codina R, Lockey RF, Fernandez-Caldas E, Tampa, FL

Indoor Exposure to Formaldehyde at Concentrations Below 50 ug/m 3 Does Not Contribute to Asthma Development G6rski P MD, Palczynski C MD, Stankiewixz J MD, Kolacinska B MD, Ruta U MD, Gruchala J MD, Krakowiak A MD, Szulc B MD, Jakubowski J MD, Hanke W MD, Lodz, Poland

94 In Utero Exposure to Tobacco Smoke Hossny E MD, Hosni A PhD, Mabrouk R MD, Cairo, Egypt

95 Formaldehyde and Respirable Suspended Particles Levels in Louisiana Homes Lemus-Olalde R MSc, Akers TG PhD, Abdelghani A ScD, New Orleans, LA

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J ALLERGY CLIN IMMUNOL Program 447 VOLUME 97, NUMBER 1, PART 3

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Mechanism of Persistent Inflammation in RADS and RUDS Meggs WJ MD, Elsheikh T MD, Metzger WJ MD, Albernaz M MD, Bloch R MD, Greenville, NC

Respiratory Function in Workers Exposed to Pesticides Jones SM MD, Burks AW MD, Roberson PK PhD, Helm RM PhD, Little Rock, AR

Total Serum IgE in Trimellitic Anhydride Induced Asthma Backman KS MD, Shaughnessy MA BS, Harris KE BS, Grammer LC MD, Chicago, IL

ALLERGEN AND EXTRACT CHARACTERIZATION

99 Factors Affecting the Inhibition ELISA for Determining Potency of Dermatophagoides Mite Extracts Plunkett GA PhD, Dailey FA PhD, Baldwin LD BS, Spokane, WA

100 Cross-Reactivity of New Grass Extracts in Percutaneous Testing Condemi JJ MD, Smith PH MD, Rochester, NY

101 Manufacture and Analysis of 100,000 BAU/mL and 10,000 BAU/mL Standardized Grass Pollen Extracts Lally P BS, Featherstone L BS, Tompkins B BS, King J BS, Weitz L BS, Baldwin L BS, Plunkett G PhD, Spokane, WA

102 Computer-Assisted Measurement of Skin Test Wheals Smith PH MD, Condemi JJ MD, Baum J MD, Rosier RN MD, Rochester, NY

103 Skin Testing Strategies in the Diagnosis of Cat Allergy Luka RE MD, Wolff A MD, Bielory L MD, East Orange, NJ

104 Pharmacia CAP System vs. Intradermal Skin Test - One Year Experience on Asthmatic Children Niu C-K MD, Lee C-C MD, Hunag S-C MD, Kaohsiung, Taiwan

105 Fel d I Levels in Cat Anal Glands Vervloet D MD, Dornelas De Andrade A PhD, Magalon C, Magnol JP, Lanteaume A MSc, Charpin D MD, Birnbaum J MD, Marseille, France

106 Purification and Characterization of the Plantain (Plantago lanceolata) Allergen Pla I 1 Weber B PhD, Kahlert H PhD, Petersen A PhD, Fiebig H PhD, Cromwell O PhD, Reinbek, Borstel, Germany

107 The Roles of Mannan (Mn) and a Secreted Enzyme, Acid Protease (AP), as Allergens of Candida albicans (Calb) Akiyama K MD, Shida T MD, Yasueda H PhD, Mita H PhD, Yanagihara Y PhD, Saito A BS, Hasegawa M MD, Maeda Y MD, Yamaguchi H MD, Takesako K PhD, Sagamihara, Kanagawa, Japan

i08 Expression of the Recombinant Lepidogiyphus Destructor Major Allergen Lep d 2 Schmidt M PhD, Johansson E PhD, Olsson S BS, van Hage-Harnsten M MD PhD, Stockholm, Sweden

109 Partial Characterization of the Silk Allergens in Mulberry Silk Extract Zaoming W MD, Codina R MS, Fernandez-Caldas E PhD, Lockey RF MD, Bukanz SC MD, Tampa, FL; Beijing, China

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448 Program J ALLERGY CLIN IMMUNOL JANUARY 1996

110 Partial Characterization of Fraxinus chinensis (Urapan) Allergens and Cross-Reactivity Among Different Fraxinus Species and Olea Europea (Olive) Rodriguez A, Codina R, Fernandez-Caldas E, Leal FC, Lockey RF, Tampa, FL; Bogota, Colombia

111 Allergens of Horse Dander: Comparison Between Breeds and Individual Animals Using Immunoblotting Dreborg S MD PhD, Felix K PhD, Femindiz R PhD, Einarsson R PhD, LinkOping, Sweden

112 Study of Bermuda Pollen IgE-Binding Protein, BG60: Characterization of its Physicochemical Property Su SN PhD, Huang SW MD, Lee YC PhD, Taipei, Taiwan; Gainesville, FL; Baltimore, MD

113 Allergenic Components in Three Different Species of Pencillium: Cross-Reactivity Among Major Allergens Shen HD MS, Lin WL BS, Tsai JJ MD PhD, Han SS MD PhD, TaipeL Taiwan

114 Cross-Allergenicity of the House Dust Mites Euroglyphus Maynei and Blomia Tropicalis Arlian LG PhD, Morgan MS PhD, Feruandez-Caldas E PhD, Dayton, OH," Madrid, Spain

115 Autologous Western Blotting with House Dust in Atopic Subjects Pearson DJ MD, Lees M, Manchester, United Kingdom

116 Cross-Reactivity Studies of Lepidoglyphus Destructor and Blomia Tropicalis Johansson E PhD, Machado L MD PhD, Johansson SGO MD PhD, van Hage-Hamsten MD MD PhD, Stockholm, Sweden," Sao Paulo, Brazil

117 Bovine Dander Allergen BDA20 is a Lipocalin Identical or Closely Related to Bos d 2 Mantyjarvi R MD, Rytkonen M MSc, Pentikainen J PhD, Rautiainen J MSc, Virtanen T MD, Santa H MSc, Laatikainen R PhD, Kuopio, Finland

118 Quantification of the Major Allergen Pla 11 from Plantain Extracts Using Monoclonal Antibodies Kahlert H PhD, Weber B PhD, Cromwell O PhD, Fiebig H PhD, Reinbek, Germany

119 Characterization of the Saltmarsh Fungi Phaeosphaeria Spartinicola Janowski MC, Newell SY PhD, Phillips AE, Smith L MD, Wray BB MD, Chrzanowski RR MD, Dolen WK MD, Augusta, GA

120 PCR Identification of Multiple Alter-Naria (ALT) cDNA Segments Containing Alt al Sequence Hu F DVM, Pacheco F MS, Landuyt J BS, Barnes C PhD, Portnoy J MD, Kansas City, MO

121 Analysis of IgE Antibody Responses to D. Pteronyssinus and Blomia tropicalis Using Recombinant Group 5 Allergens Vailes LD MS, Rizzo MC MD, Naspitz CK MD, Montealegre F PhD, Fernandez-Caldas E PhD, Platts-Mills TAE MD PhD, Chapman MD PhD, Arruda LK MD, Charlottesville, Vii; Tampa, FL; Ponce, PR; Sao Paulo, Brazil

122 Allergic Rhinoconjunctivitis by Lilac Flowers Sainza T MD, Barrio M MD, Montoro A MD, Ordoqui E MD, Baeza ML MD, Madrid, Spain

123 Immunologic Responses to Chironomus Flaviplumus in Atopic Children Kang HY, Lee KY, Kim DS, Kim KE, Jeong B J, Seoul, Korea

124 Characterization of Oilseed Rape Allergens Focke M PhD, Hemmer W PhD, Bracun R MD, Wolf S MD, Wantke F MD, G6tz M MD, Jarisch R MD, Vienna, Austria

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J ALLERGY CLIN IMMUNOL Program 449 VOLUME 97, NUMBER 1, PART 3

125 Evaluation of In Vitro Cross-Reactivity Between Allergens from Birch and Ash Pollen Wekkeli M, Focke M, Hemmer W, Bracun R, Wolf-Abdolvahab S, GOtz M, Jarisch R, Vienna, Austria

126 Helminth Secretory Proteins are Related to Wasp Antigen 5 by Both Sequence and Immunologic Cross-Reactivity Hoffman DR PhD, Hawdon JM PhD, Jones BF PhD, Hotez PJ MD PhD, Greenville, NC; New Haven, CT

127 Cross-Reactivity of Major Antigens and Allergens in the Saliva of Different Mosquito Species Brummer-Korvenkontio H MD, Palosuo K, Palosuo T, Reunala T, HelsinskL Finland

EXPOSURE ASSESSMENT

128 Threshold Values for IgE Sensitization by Indoor Major Cow Hair Allergen Bos d 2 Hinze S, Bergmann KC, Lowenstein H, Hansen GN, Bad Lippspringe, Germany; Horsholm, Denmark

129 Cat Major Allergen (Fel d I): Correlation Between Dust and Airborne Exposure Using a Portable Air Sampler OR M BS, de Blay F MD, Gries P PhD, Pauli G MD, Strasbourg, France

130 Indoor Air Quality in Special Daycare Centres for Atopic Children Emenius G EHO, Egmar AC RN, Larsson PH MSc, Christensson B MSc, Wickman M MD PhD, Stockholm, Sweden

131 Comparison of Two Fel D 1 Assays in House Dust Samples Hoppe A MD, Hoffmann A DVM, Wahl R PhD, Mtisken H MD, Bergmann K-Ch MD, Bad Lippspringe, Langen, Reinbek, Germany

132 Measurement of Ficus benjamina Antigen Using Polyclonal Antibody Sandwich ELISA Faller M MD, de Blay F MD, Lett E PhD, V6rot A BS, Bessot JC MD, Pauli G MD, Wachsmann PhD, Strasbourg, France

133 Comparative Study of Air Samplers Measuring Airborne Fel d 1 Ohmes C MD, V6rot A BS, Pauli G MD, de Blay F MD, Strasbourg, France

134 A New Continuous Volumetric Recording Indoor Air Sampler Stern MA FRCP, Allitt U BA, Corden JM BSc, Millington WM BSc, Leicester, Cambridge, England

135 Documenting Variability in Indoor Allergen ELISAs Higgins K, Chew G, Davidian M, Milton D, Burge HA, Boston, MA

136 Automation of a Spreadsheet Model for Selection of Geographically Relevant Allergens for Skin Testing McGerity J MD, Jorgensen J RN, Rosen A BSEE, San Francisco, CA

137 Comparison of Allergic Sensitivity to Perennial and Seasonal Allergens in Patients Presenting for Initial Allergen Evaluations Wedner HJ MD, Dixit A PhD, Lewis WH PhD, Crozier W MD, St, Louis, MO; Corpus ChristL TX

138 Skin Prick Test (SPT) Reactivity in East and West Germany is Changing Sch~ifer T MD, Kr~imer U PhD, Behrendt H MD, Vieluf D MD, Ring J MD, Hamburg, Dusseldorf Munich, Germany

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450 Program J ALLERGY CLIN IMMUNOL JANUARY 1996

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Aeroallergen Allergy in a Population of Four Year Olds Ridout S BM, Tariq S MRCP, Mat-thews S RGN, Stevens M RGN, Hide D MD, Newport, Isle of Wight, United Kingdom

Aerobiology: Grass Pollen Forecasting Models Kagen SL MD, Muthiah R PhD, Knoll R, Graphos G, DeStasio B PhD, Appleton, Green Bay, WI

Daily Variation of Airborne Ragweed (RW) Allergen Concentration Landuyt J BS, Pacheco F MS, Hu F DVM, Portnoy J MD, Barnes C PhD, Kansas City, MO

Allergic and Immunologic Profile of Symptomatic Persian Gulf War Veterans Lee KG MD, Kraske GK MD, Klaustermeyer WB MD, Los Angeles, California

Influence of Gaseous Pollutants on Pollen Viability (PV), Germination (PG) and Protein Release (PR) Thomas P MD, Deutinger P MD, Heubl G PhD, Strube D PhD, Przybilla B MD, Munich, Germany

Determination of Humulus Scandens Pollen Specific IgE by Two In Vitro Assay: ELISA and Phamacia CAP System (CAP) Yin J MD, Wang L MD, He H, Ye S MD, Beijing, China

Consistency of Season Aerobiological Peak Pollen Counts 1992-95 Ford L MD, Loker R PA-C, Hartel R RN, Papillion, NE

Analysis of Geographic and Demographic Patterns of Aeroallergen Sensitivity Using a Spreadsheet Model Avila PC MD, McGerity JL MD, Jorgensen J NP, Gershman NH MD, Adelman DC MD, Kishiyama JL MD, San Francisco, CA

Evaluation of Allergen Levels and Air Quality in Central Wisconsin Grade Schools Twiggs JT MD, Marx JJ Jr PhD, Ault BJ RN, Gray RL BS, Marshfield, WI

MITES

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AND MOLDS

Seasonal Variation of Airborne Allergen Concentration Landuyt J BS, Barnes C PhD, Pacheco F MS, Hu F DVM, Portnoy J MD, Kansas City, MO

Distribution of Mold Spores in Indoor and Outdoor Air During Summer Season Kim YK MD, Lee YJ MD, Kim K-E MD, Lee KY MD, Seoul, Korea

Stachybotrys Atra-Induced Lung Injury in Mice Reijula KE MD, Nikulin M MSci, Jarvis BB PhD, Hintikka EL DVM, College Park, MD; Helsinki, Finland

Immunoreactive Alternaria Allergen in House Dust: Presence in Prairie Homes in the Absence of Environmental Mold Spores Becker AB, Muradia G, Vijay HM, Watson WTA, Peng Z, Simons FER, Winnipeg, Ottawa, Canada

Population Assessment of Airborne Molds Utilizing Two Volumetric Air Samplers in a Study of Five Central Florida Buildings Cruz-Perez P MS, Gennaro RN PhD, Klotz SD MD, White RS PhD, Sweeney MJ PhD, Orlando, FL

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153 Indoor Allergen Loads in Homes in South Louisiana Homer WE PhD, Pinero D BS, Reese G PhD, Lehrer SB PhD, New Orleans, LA

154 Health Risk Assessment of Fungi in Homes Verhoeff AP PhD, Burge HA PhD, Amsterdam, The Netherlands; Boston, MA

155 A Comparison of Post-Flooding Fungal Contamination and Related Health Effects in Reoccupied Buildings in Western and Eastern Missouri Dixit A PhD, Clardy S BS, Lewis WH PhD, Wedner HJ MD, St. Louis, Jefferson City, MO

156 Relationship Between Intradomiciliar Bacteria and Fungi Exposure and Asthma Rizzo MC MD, Naspitz CK MD, Fernandez-Caldas E PhD, Mimica I MD, Lockey RF MD, So16 D MD, Sao Paulo, Brazil; Tampa, FL

157 Relationship Between Levels of Fungi in House Dust and Occupant's Responses to Home Characteristics Questions Muilenberg ML, Burge HA, Chew GL, Gold D, Boston, MA

158 Time Series Analysis of Mold Aeroallergens in Relation to Meterologic Parameters Katial RK MD, Zhang Y PhD, Jones RH PhD, Dyer PD MD, Denver, CO

159 A Case Study of Airborne Fungi: Why Viable Sampling Is Not Enough Levetin E PhD, Shaughnessy R PhD, Stetzenbach L PhD, Tulsa, OK; Las Vegas, NV

160 Intranasal Provocation with Euroglyphus Maynei Extract Lockey RF MD, Kemp SF MD, Fern~tndez-Caldas E PhD, Tampa, FL

161 House Dust Mite Allergens in Mattresses. A Cross Sectional Analysis in a Temperate Costal Area Mosbech H MD PhD, Steensen M MD, Veggerby C BS, Poulsen L PhD, Heinig JH MD, Johnsen C MD, Copenhagen, Denmark

162 Impact of an Individual Teaching Program on Environmental Control in Moderate to Severe Asthmatics C6t6 J, Robichaud P, Boutin H, Filion A, Lavall6e M, Krausky M, Rouleau M, Malo JL, Cartier A, Boulet LP, Quebec, Montreal, Canada

163 Clinical Study of Bedding Covers in Mite-Allergic Asthmatic Patients Birnbaum J MD, de Blay F MD, Paty E MD, Just J MD, Panli G MD, Vervloet JD MD, Charpin D MD, Marseille, France

164 Allergen Transfer Chamber: A New Method for Testing Allergen Barriers Ransom JH MD, Halsey JF PhD, Topeka, Lenexa, KS

165 Mite Cultures on Delicate Garments and Mite Control by Low Temperature Washing (LTW) with Commerical Detergents and a Benzyl Benzoate Containing Additive Bischoff ERC PhD, Kniest FM PhD, Kirchheim-Bolanden; Reinbek, Germany

166 Dust Mites' Survival at High Temperatures Dippold JS BS, Arlian LG PhD, Rapp CM MS, Chang JS PhD, Dayton, OH; Research Triangle Park, NC

167 Effect of Dust Mite Allergen Avoidance in Homes of Children Hospitalized with Acute Asthma Hayden M RN MS, Perzanowski M BS, Call R MD, Matheson L BS, Scott J MD, Platts-Mills TAE MD PhD, Charlottesville, VA

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168 Correlation Between Airborne and Dust Exposure to Mite Group Allergens Using Petri Dish Method de Blay F MD, Mahler S PhD, Gries P MD, Ott M BS, Pauli G MD, Strasbourg, France

169 A Comparison of Monoclonal Antibody (mAb)-Capture and Der f I-Capture ELISAs for Measurement of Dermatophagoides farinae (Der f) I-Specific IgE Xu W PhD, Simons FER MD, Peng Z MD, Winnipeg, Manitoba, Canada

170 Comparison of Guanine Levels and Mite Allergen Content in House Dust Samples Baker RR PhD, Arant CB BS, Rupp NT MD, Augusta, GA

171 Peak Expiratory Flow (PEF) Variability and Exposure to Dermatophagoides farinae O'Rourke MK PhD, Jin S PhD, Atmowidjojo A MS, Tucson, AZ

172 Euroglyphus Maynei (Em) Skin Test Reactivity in Patients with Asthma and or Rhinitis in Rio de Janeiro Geller M MD, Esch RE PhD, Fernandez-Caldas E PhD, Rio de Janeiro, Brazil; Lenoir, NC; Tampa, FL

173 Prevalence of Blomia tropicalis Sensitization in Singapore Lee BW MD, Chew FT BSc, Goh DYT MD, Wong GW BSc, Singapore

174 Prevalence of Storage Mite Sensitisation in Urban Patients R0seler ST MD, Wagenmann M MD, Bachert C MD, Di~sseldorf, Germany

175 Sensitization to Dermatophagoides Siboney, Blomia Tropicalis and Other Domestic Mites in Asthmatic Patients as Measured by SPT and Specific IgE Femindiz R PhD, Casas R BSc, Dreborg S MD PhD, Link6ping, Sweden

176 Respiratory Allergy in Library Workers: Are Mites Implicated? S~inchez-Medina M MD, Zarante I MD, Rodrfguez MN MPH, Ramirez MR RN, Santafd de Bogota, Colombia

177 Allergen Avoidance Measures Reduce the Risk of the Development of House Dust Mite Allergy in Atopic Infants Oei HD MD, de Haas R MD, Tjiook SB MD, Dordrecht, The Netherlands

178 Weekly Variation of Dust Mite and Alternaria in House Dust Guss J, Barnes C PhD, Landuyt J BS, Pacheco F MS, Hu F DVM, Portnoy J MD, Kansas City, MO

179 Sensitization to House Dust Mites in Asthmatic Children in Argentina and Cross-Reactivity Studies Baena-Cagnani C, Fernandez-Caldas E, Arlian LG, Codina R, Cuello M, Patino C, Lockey RF, Cordoba, Argentina," Dayton, OH; Tampa, FL

180 Prevalence of the House Dust Mite (Dermatophagoides farinae and D pteronyssinus) in a Southern United States Tertiary Care Hospital Babe Jr KS MD, Arlian LG PhD, Dippold J BS, Marney Jr SR MD, Nashville, TN; Dayton, OH

181 Respiratory Allergies Due to the Basiodiomycete Hemileia Vastatrix Croce J, Croce M, Costa Manso E, Takayama L, Gambale W, Sao Paulo, Brazil

182 Angioedema Following Dust Mite Exposure Presenting as Suspected Food Allergy Skoda-Smith S MD, Mullen GR PhD, Oi F PhD, Atkinson TP MD PhD, Birmingham, AL; Auburn, AL

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IMMUNOTHERAPY

183 Chemokine Production by Peripheral Blood Mononuclear Cells During Rush Venom Immunotherapy Akoum H PhD, Tsicopoulos A MD, Vorng H, Wallaert B MD, Tonnel AB MD, Lille, France

184 Inactivation of Skin and Pulmonary Mast Cells and Basophils in Sensitized Rats and Dogs by Non-Allergenic Conjugates of Allergen and mPEG Sehon AH DSc, Lang GM PhD, Wakefield RD, Kozak MM, Becker AB MD, Winnipeg, Manitoba, Canada

185 Immunomodulating Activity of the Extract from High Mycelium Fungus Polyporus Squamosus Babahskin AA MD PhD, Logina NY MD, Nolte H MD PhD, Du Buske LM MD, Boston, MA; Moscow, Russia," Copenhagen, Denmark

186 Blood Basophils are Influenced by Ultra-Rush Bee Venom Immunotherapy: Changes in Histamine Release and Leukotriene Secretion Jutel M MD, MUller UR MD, Rihs S, Fricker M MD, Pichler WJ MD, Dahinden C MD, Bern, Switzerland

187 Site-Directed Mutagenesis of Recombinant Der p 2 Decreases In Vitro and In Vivo Reactivity with IgE Ab Smith A PhD, Wheatley L MD, Chapman M PhD, Charlottesville, VA

188 Analysis of T-Cell Epitopes of Group 5 Grass Pollen Allergens MUller W-D PhD, Karamfilov T PhD, Fahlbusch B PhD, Sttiwe H-T PhD, Fiebig H PhD, dena, Reinbek, Germany

189 Allergenic Components of the Russian Thistle (S. Kali) Pollen de la Hoz B, Martinez J, Tejedor MA, P6rez C, Martinez A, Sastre J, Albacete, Spain

190 Fel d 1 Peptides (Allervax® Cat) in Cat-Allergic Subjects Simons FER MD, Watson WTA MD, Dilay DJ RN, Gillespie CA RN, lmada M MD PhD, HayGlass KT PhD, Winnipeg, Canada

191 Kinetics of Radiolabelled Allergen Administed by Sublingual and Oral Route Canonica GW MD, Bagnasco M MD, Passalacqua G MD, Motta C MD, Bartolomei M MD, Mariani G MD, Genoa, Italy

192 Assessment of Expression and Allergenicity of Recombinant Mouse Major Urinary Protein Produced in a Baculovirus System Stacks J BS, Cavaggione AJ PhD, Rosenwasser L J, Denver, CO; Parma, Italy

193 Isolation and Partial Purification of Allergenic Components of the Pollens Paspalum Notatum and Melaleuca Leucadendron Hunter SL MS, Gennaro RN PhD, Klotz SD MD, Sweeney MJ PhD, White RS PhD, Orlando, FL

194 Variations in the Administration of Allergy Immunotherapy (AI) in Kansas Wiens LA MD, Soeken LA RN, Fischer KA RN, Walker D BS, Great Bend, KS

195 Deaths Associated with Skin Testing and Immunotherapy Reid M MD, Gurka G MD, San Francisco, CA; Arlington, MA

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Molecular Changes Following Vaccination and Immunotherapy with a Multi-Epitopic Recombinant Allergen Mohapatra SS PhD, Cao Y MD, Luo Z MD, Winnipeg, Canada

Reduction of Oral Corticotherapy by Sublingual Immunotherapy (IT): Double-Blind Placebo-Controlled Study in Grass Pollen Allergy Clavel R, Andr6 C, Bousquet J, Rh6ne Moyen Study Group, Montpellier, Fresnes, France

Immunotherapy as Preventive Allergy Treatment (PAT) Jacobsen L, Dreborg S, Moiler C, Valovirta E, Wahn U, Niggemann B, Koller D, Urbanek R, Halken S, Host A, Lowenstein H, Denmark, Sweden, Finland, Germany, Austria

Serum IgG4: Monovalent or Possibly Hetero-Bivalent Antibodies? Schuurman J BS, Perdok GJ MS, Aalberse RC PhD, Amsterdam, The Netherlands

Nasal Immunotherapy (NIT) to Parietaria: Follow-up of a Double Blind Study Passalacqua G MD, Albano M MD, Riccio A BS, Pronzato C MD, Falagiani P BS, Scordamaglia A MD, Canonica GW MD, Genoa, Milan, Italy

Tolerance of an Olea europaea Pollen Extract in Asthmatic Patients from a High Exposure Area Gonz/dez P, Florido F, Sa6z B, de la Torre F, Jadn, Spain

Duration of Efficacy of Specific Immuno-Therapy (SIT) with Dermatophagoides pteronyssinus (Der p) Extract After Its Cessation is Related to Skin Test Reactivity Des Roches A, Paradis L, Knani J, Hejjaoui A, Dhivert H, Michel FB, Bousquet J, Montpellier, France

Incidence of False Positive Reactions in Allergy Testing Using Extract Mixes Weldon D MD, College Station, TX

High Prevalence of Sensitization to Anisakis Simplex (AK) in Patients with Increased Levels of Total IgE Pascual C, Crespo JF, Ortega N, Ornia N, San-Martin MS, Martin-Esteban M, Madrid, Spain

Analysis of Mild Systemic Side Effects of Specific Immunotherapy GOtz M, Wantke F, Hemmer W, Focke M, Jarisch R, Vienna, Austria

Effect of Oral Immunotherapy (O-IT) on Short Ragweed (SR) Pollen Allergy Seiler BA MD, Angelini BL RN BSN, Van Deusen M BS, Cordoro KM BS, Wood L PhD, Skoner D MD, Pittsburgh, PA; Cincinnati, OH

LABORATORY IMMUNOLOGY

207 Rapid and Simultaneous Quantitation of Specific IgE Against 20 Purified Allergens in Allergic Patients Sera By Checkerboard Immunoblotting (CBIB) Rabillon J, Musu T BS, David B MD, Dandeu JP PhD, Paris, France

208 Clinical Efficiency of UniCAP T M Specific IgE Yman L PharmD, Ewan P MD, deGroot H MD, Lange C MD, Lindholm N MD, Paganelli R MD, Roovers M MD, Sastre J MD, Uppsala, Cambridge, Rotterdam, Bonn, Gothenburg, Rome, Tilburg, Madrid

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J ALLERGY CLIN IMMUNOL Program 455 VOLUME 97, NUMBER 1, PART 3

209 Total IgE Normal Ranges for Pediatric SERA Lau S MD, Wahn U MD, Berlin, Germany

210 Specificity of Rabbit Sera Immunized with Either Ammoniated (AL) or Nonammoniated (NAL) Latex Extracts Tomazic V J, Truscott W, Rockville, MD; San Diego, CA

211 An Indirect Bioassay to Detect Spontaneous Production of Nitric Oxide in Asthma Jaimez L MD, Wang SF MS, Matin A PhD MD, Frieri M PhD MD, East Meadow, NY

212 Serological Diagnosis of Chagas Disease: A Confirmatory Assay by Western Blot Using Preserved Protein Antigens of Trypanosoma Cruzi Mendes RP MSc, Hoshino-Shimizu S PhD, Moura da Silva AM PhD, Mota I Prof, Luquetti AO MSc, Heredia RAG MD, Leser PG PhD, Uberlandia, Brazil

213 Specific Tear Prealbumin an Adjunct to Lysozyme's Activity in the Human Josephson AS MD, Drew H MS, Brooklyn, NY

214 Immortalization of an Epithelial Cell Line Derived from a Nasal Polyp Campbell A PhD, Lebel B PhD, Crampette L MD, Mainprice B PhD, Bousquet J MD, Montpellier, France

215 HLA-DR2 is Associated with Increased Risk of Renal Allograft Failure in Alport's Syndrome Karadsheh A MD, Rao P PhD, Das D, Kissinger P PhD, Kumar P MD, New Orleans, LA

POSTER SYMPOSIUM SATURDAY, MARCH 16, 1996

2:00 PM TO 5:00 PM

FOOD ALLERGY Moderators: Brett Kettelhut, M.D., Hugh Sampson, M.D.

216 The Dose Relationship of Specific IgE to Severity of Food Hypersensitivity Zhou CY, Koenig GA, Crocker IC, Romero FA, Bewtra AK, Townley RG, Madrid, Spain

217 Loratadine Improves Intestinal Hyperpermeability in Children with Atopic Dermatitis (AD) Related to Food Allergy (FA) Molkhou P MD, Rocchiccioli F PhD, Wessel F MD, Antoine C PhD, Cougnard J, Czarlewski W MD, Paris, Nantes, France

218 Allergenicity of Individual Cow Milk Proteins in DBPCFC-Positive Milk Allergic Adults Norgaard A MD PhD, Bernard H PhD, Wal J-M DSc, Peltre G DSc, Skov PS MD PhD, Poulsen LK PhD, Bindslev-Jensen C MD PhD, Copenhagen, Denmark; Paris, France

219 IgE-Mediated Cow's Milk Allergy (IgE-CMA) In Adults Schwartz RH MD, Peers LB RN, Rochester, NY

220 Oral Hyposensitzation in a Patient with IgE-Mediated Hypersensitivity to Milk Vieluf I, Vieluf D MD, Hamburg, Germany

221 Allergen in the Steam of Cooking Foods Figueroa S MD, McCullough J BA, Ownby DR MD, Detroit, MI

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222 Histamine in Wine: Bronchoconstriction After a Double Blind Placebo Controlled Red Wine Provocation Test Wantke F, Hemmer W, Haglmtiller T, G6tz M, Jarisch R, Vienna, Austria

223 Allergenicity of Gourmet Nut Oils Processed by Different Methods Brown RL MD, Haapanen LAD BS, Teuber SS MD, Davis, CA

224 Investigation of the Familial Nature of Peanut Allergy and its Association with Tree Nut and Legume Allergy Warner JO MD, Hourihane JO'B MRCPI, Bicknell CM, Dean TP PhD, Southampton, United Kingdom

225 Identification of Peanut Allergens by FPLC & Immunoblotting Using Sera from 50 Peanut Allergic Patients Clarke MCA, Dean KR PhD, Hourihane JO'B MRCPI, Warner JO MD, Dean TP PhD, Southampton, United Kingdom

226 Age of Onset and Reported Symptoms in 500 Peanut Allergics Bicknell CM, Hourihane JO'B MRCPI, Dean TP PhD, Warner JO MD, Southampton, United Kingdom

227 Allergic Reaction to Measles-Mumps-Rubella (MMR) Vaccine in a Girl Tolerant to Egg-Protein Levy Y MD, Kornbrot B MD, Danon YL MD, Petah-Tikva, lsrael

228 Safe Administration of Influenza Vaccine to Egg-Allergic Patients James JM MD, Zeiger RS MD PhD, Lester MR MD, Mansfield LE MD, Fasano MB MD, Gem JE MD, Windom H MD, Sampson HA MD, Little Rock, AR; San Diego, CA; Boston, MA; El Paso, TX," Winstom Salem, NC; Madison, W1; Tampa, FL; Baltimore, MD

229 Effect of Early Feeding of Soy (SF), Extensively-Hydrolyzed Casein (EHCF), and Partially-Hydrolyzed Whey (PHWF) Formula on the Development of Allergic Manifestations in Children During the Second Year of Life Porch MC RN, Shahane A, Elston RC PhD, Leiva L PhD, Sorensen RU MD, New Orleans, LA

230 Influence of Maternal Dietary Restriction During Lactation on Infants T-Cell Responses and IgE Levels Dean T PhD, Pollard C MPhil, Bevin S MRCP, Hourihane J MRCPI, Little S PhD, Clarke M BSc, Warner JO MD, Southampton, United Kingdom

231 Influence of Maternal Diet During Lactation Upon Allergic Manifestation in Infants - Tolerisation or Sensitisation? Pollard C MPhil, Bevin S MRCP, Little SA PhD, Hourihane JO'B MRCPI, Warner JO MD, Dean TP PhD, Southampton, United Kingdom

232 Comparison of Taste Perference Development Between Breastfed Infants and Infants Receiving Standard, Soy or Hydrolysate Formulae Still S MBChB, Little SA PhD, Pollard C MPhil, Bevin S MRCP, Hourihane JO'B MRCPI, Harris G PhD, Warner JO MD, Dean TP PhD, Southampton, Birmingham, United Kingdom

233 Maternal Food Antigen Avoidance During Lactation and Allergy During the First 10 Years of Age Hattevig G MD PhD, Sigurs N MD PhD, Kjellman B MD PhD, SkOvde, Boras, Sweden

234 Food Allergens are Stable to Digestion in a Simple Model of the Gastrointestinal Tract Astwood JD PhD, Fuchs RL PhD, St, Louis, MO

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J ALLERGY CLIN IMMUNOL Program 457 VOLUME 97, NUMBER 1, PART 3

235 Cloning and Sequencing of a Walnut (Juglans regia) Food Allergen and its Sequence Similarity with Other Seed Storage Proteins Teuber SS MD, Dandekar AM PhD, Peterson WR BS, Uratsu SL BS, Davis, CA

ORAL SESSION SATURDAY, MARCH 16, 1996

3:00 PM TO 5:00 PM

NEW FRONTIERS IN ASTHMA RESEARCH Moderators: Susan Squillace, M.D. and David Stempel, M.D.

236 3:00 pm Assessments of Eosinophil Cationic Protein (ECP) in Nasal Washes from Wheezing Infants LaRussa JB MD, Rakes GP MD, Murphy DD RN, Platts-Mills TAE MD PhD, Heymann PW MD, Charlottesville, VA

237 3:12 pm Effects of Dexamethasone Administered During Acute Viral Bronchiolitis in Brown Norway (BN) Rats Kumar A MD, Sorkness RL PhD, Kaplan MR BS, Castleman WL DVM PhD, Lemanske Jr RF MD, Madison, WI

238 3:24 pm IL-8 and Soluble ICAM-1 (sICAM-1) Concentration in Bronchoalveolar Lavage (BAL) of Asthmatic Children and Infantile Wheezers Dean TP PhD, Marguet C MD, Mallet E MD, Warner JO MD, Rouen, France; Southampton, United Kingdom

239 3:36 pm IL-2 & IL-4 Mediates Allergen Induced Glucocorticoid (GC) Receptor (R) Binding Abnormalities Nimmagadda SR MD, Szefler SJ MD, Spahn JD MD, Surs W BS, Leung DYM MD PhD, Denver, CO

240 3:48 pm Inhibition Of The Allergen-Induced Late Phase Asthmatic Reaction by Oral Cyclosporin A (CsA) Sihra BS MD, Walker SM, Kon OM MD, Barnes NC MD, Kay AB MD, London, United Kingdom

241 4:00 pm Attenuation of the Airways Response to AMP by Inhaled Heparin in Asthmatics: Study of the Time-Course Polosa R, Crimi N, Magroo S, Vancheri C, Mastruzzo C, Paolino G, Mistretta A MD, Catania, Italy

242 4:12 pm Human Eosinophils (Eos) Express RANTES mRNA and Store and Release Biologically Active RANTES Protein Ying S, Meng Q, Taborda-Barata L, Corrigan C J, Barkans J, Assoufi B, Moqbel R, Durham SR, Kay AB, London, United Kingdom

243 4:24 pm The Association of Total IgE, Indoor and Outdoor Allergen Specific IgE and Asthma - The 3 Schools Study Sporik RB MD, Squillace SP MD, Ingram JM MD, Price W MD, Rose G BS, Honsinger R MD, Platts-Mills TAE MD PhD, Charlottesville, VA

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244 4:36 pm

245 4:48 pm

Superantigens Alter Glucocorticoid Receptor Binding (GCR) Affinity In Vitro Prager SS MD, Leung DYM MD PhD, Nimmagadda SR MD, Surs W BS, Spahn JD MD, Szefler SJ MD, Denver, CO

Inflammatory Constituents of Brochoalveolar Lavage (BALF) and Lung Interstitium in Cockroach Sensitized and Sham Sensitized Guinea Pigs Miller BM MD, Kang BC MD, Gindling H MS, Sajadi K BS, Thompson JS MD, Lexington, KY

REGULATION OF ALLERGIC RESPONSE Moderators: John Costa, M.D. and Robert Rich, M.D.

246 3:00 pm Intra- and Interindividually Restricted TCR-VI3 Usage of Allergen-Specific T Cell Lines Daser A MD, Parronchi P MD, Giannarini L MD, Sampognaro S, Maggi E MD, Rombola G MD, Wahn U MD, Romagnani S MD, Renz H MD, Berlin, Germany," Florence, Italy

247 3:12 pm Specificity and Functional Characteristics of Bet v 1-Specific T Lymphocytes Derived from Atopic Patients van Neerven RJJ PhD, Sparholt SH PhD, Larsen JN PhD, Ipsen H MSc, Schou C PhD, Horsholm, Denmark

248 3:24 pm MHC Class II Restriction and TCR Beta Usage in Patients with Allergic Bronchopulmonary Aspergillosis (ABPA) Chauhan B PhD, Slavin RG MD, Hutcheson PS BA, Bellone CJ PhD, St. Louis, MO

249 3:36 pm Antigen-Specific T Cells are Activated at Early Times Following Antigen Inhalation Lou J MD, Blumenthal MN MD, Chen ZM, Jenkins MK MD, Minneapolis, MN

250 3:48 pm Grass Pollen Induced IL-5 Production by Peripheral Blood Mononuclear Cells (PBMC) is Increased in Allergic Rhinitis and Inhibited by Immunotherapy (IT) Till S J, Corrigan C, Huston D, Dickason R, Walker S, Lamb J, Kay AB, Durham SR, London, United Kingdom; Houston, TX

251 4:00 pm Phase I Study of Anti-IgE Recombinant Humanized Monoclonal Antibody rhuMAB-E25 (E25) in Adults with Moderate to Severe Asthma Corren J MD, Froehlich J MD, Schoenhoff M PhD, Spector S MD, Rachelefsky G MD, Schanker H MD, Patnaik M MD, Siegel S MD, Los Angeles, South San Francisco, CA

252 4:12 pm Development of a Pulmonary Inflammatory-Type Reaction in Humanized SCID Mice After Sensitization by Allergen Aerosols Duez C PhD, Tsicopoulos A MD, Janin A MD, Wallaert B MD, Tillie-Leblond I MD, Andre C PhD, Hamid Q MD, Tonnel A-B MD, Pestel J PhD, Lille, France

253 4:24 pm Allergen Confirmation-Dependent T Cell Cytokine and Antibody Isotype Patterns in Bee Sting Sensitized Subjects Akdis AC, Blesken T, Wymann D, Akdis M, Faith A, Blaser K, Davos, Switzerland

254 4:36 pm Trans-Splicing of Ig Heavy Chain RNA Transcripts in Human B Cells Fujieda S MD, Zhang K MD PhD, Lin YQ MD, Saxon A MD, Los Angeles, CA

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255 4:48 pm Isotype Switch to the Murine IgE Ce Locus in B Cells with Intact Ie and Se Sequences but Deletion of the Ce Exons Goldberg A, Oettgen HC MD PhD, Boston, MA

ENVIRONMENTAL Moderators: David

256 3:00 pm

257 3:12 pm

258 3:24 pm

259 3:36 pm

260 3:48 pm

261 4:00 pm

262 4:12 pm

263 4:24 pm

264 4:36 pm

265 4:48 pm

RISK FACTORS FOR ASTHMA Peden, M.D. and Leslie Grammer, M.D.

Daily Asthma Severity Relates to Personal Ozone Exposure and Outdoor Fungal Spores Zeiger RS MD PhD, Delfino RJ MD PhD, Coate BD MPH, Seltzer JM MD, Street DH MS, Koutrakis P PhD, San Diego, CA; Independence, OR; Boston, MA

Diesel Exhaust Particles and Ragweed Allergen In Vivo Induce TH2 Cytokine Production in the Nasal Mucosa of Ragweed-Sensitive Subjects Diaz-Sanchez D PhD, Tsien AY MD, Saxon A MD, Los Angeles, CA

Diesel Exhaust Particles Downregulate IL-10 and Enhance CD23 in PBMC's from Allergic and Non-allergic Individuals Pacheco K MD, Negri J BS, Rosenwasser LJ MD, Borish L MD, Denver, CO

Histopathological Features of RADS at Various Intervals Malo JL MD, Lemi6re C MD, Boutet M MD, Garbe-Galanti L, Montreal, Quebec City, Canada; Marseille, France

Synthetic Oligopeptides from A. Fumigatus Ribotoxin React with IgE Antibody in the Sera of ABPA Patients Kurup VP PhD, Hari V PhD, Greenberger PA MD, Castillo L, Fink JN MD, Milwaukee, WI; Detroit, MI; Chicago, IL

Monoclonal Antibody Based Purification of a Major Allergen of A. Fumigatus Reacting Significantly with IgE Antibodies in ABPA Sera Banerjee B PhD, Nair D, Kurup VP PhD, Greenberger PA MD, Hoffman DR PhD, Fink JN MD, Milwaukee, WI; Chicago, IL; Greenville, NC

Prognostic Factors for the Isocyanate-Induced Occupational Asthma (OA) Park HS MD, Nahm DH MD, Suwon, Korea

In Vitro Production of MCP-1 in Workers with Diisocyanate-Induced Occupational Asthma Lummus ZL PhD, Alam R MD, Bernstein JA MD, Bernstein DI MD, Cincinnati, OH; Galveston, TX

Outcome of Specific Bronchial Responsiveness to Occupational Agents after Removal from Exposure Lemi6re C MD, Cartier A MD, Dolovich J MD, Chan-Yeung M MD, Grammer L MD, Ghezzo H PhD, L'ArchevSque J RT, Malo J-L MD, Montreal Hamilton, Vancouver, Canada," Chicago, IL

Study of Employees with Anhydride-Induced Respiratory Disease After Removal from Exposure Grammer LC MD, Shaughnessy MA BS, Chicago, IL

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460 Program J ALLERGY CLIN IMMUNOL JANUARY 1996

THEMATIC POSTER SESSION SUNDAY, MARCH 17, 1996

12:00 PM TO 4:00 PM

ADVANCES IN ASTHMA THERAPEUTICS

266 Patient Satisfaction with a Multi-Dose Powder Inhaler (MDPI) Device in Treatment of Asthma Mahajan P PhD, Okamoto L PharmD, Schaumberg J PhD, Goldstein M MD, Research Triangle Park, NC; Philadelphia, PA

267 A Comparison of Fluticasone Propionate via DiskusrU(Accuhaler TM) Inhaler and Budesonide via Turbuhaler TM Inhaler in Adult Asthmatics Backman R MD, Pickering CAC FRCP, Baumgarten C MD, Huskisson SC MA, Meltola, Finland," Manchester, Greenford, United Kingdom; Berlin, Germany

268 Comparison Trial of Pirbuterol Acetate Administered Via a Breath-Actuated Inhaler with Albuterol Administered by a MDI with a Spacing Device Grossman J, Tinkelman DG, Ziment I, Tucson, AZ

269 Zileuton Inhibits Interleukin-4 (IL-4) Production by Peripheral Blood Mononuclear Cells (PBMC) Fisher RH MD, Lu LJ MD, Milwaukee, WI

270 Effect of Treatment with Zafirlukast (Accolate TM) on Bronchial Hyperresponsiveness in Patients with Mild-to-Moderate Asthma Rosenthal R MD, Lavins BJ MD, Hanby LA MS, Fairfax, VA; Wilmington, DE

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The Comparative Effect of Zileuton, A 5-Lipoxygenase Inhibitor, Plus Low Dose Inhaled Beclomethasone vs Higher Dose Beclomethasone for Asthma O'Connor BJ MD, Godard P MD, Dub6 LM PhD, Swanson LJ PhD, Maki R, The European Zileuton Study Group, London, United Kingdom; Montpellier, France; Abbott Park, IL

Effect of Fluticasone Propionate (FP) on Ozone (O3)-Induced Inflammatory Cell Changes, Following Segmental Allergen Challenge, in Mild Asthmatics Rusznak C MD, Wang JH MD, Khair OA MRCP, Devalia JL PhD, Davies RJ FRCP, London, United Kingdom

273 Low Doses of Inhaled Fluticasone Propionate (FP) Reduce Bronchial Hyperresponsiveness (BHR) Noonan MJ MD, Munk ZM MD, Chervinsky P MD, Dockhorn RJ MD, Pinnas J MD, Wolfe J MD, Crescenzi KL PhD, Kellerman DJ PharmD, Portland, OR; Houston, TX," New Bedford, MA; Lenexa, KS," Tucson, AZ; San Jose, CA; London, United Kingdom; RTP, NC

274 Comparison of Three Different Doses of Budesonide and Placebo on the Allergen-Induced Early Asthmatic Response (EAR) Swystun VA, Bhagat R, Kalra S, Jennings B, Cockcroft DW, Saskatoon, Mississauga, Canada

275 Inhaled Budesonide Activity Over Eosinophilic Cationic Protein (ECP) Serum Concentrations, Bronchial Hyperresponsiveness to Cold Air (BHR) and Spirographic Evolution in Asthmatic Patients Cortigiani LD, Greiding L, Grinstein M, Paulin P, Flores D, Josviack D, Moreno P, Buenos Aires - Argentina

276 Chronotherapeutic Effect of Inhaled Steroids on Asthma at 8 AM or 5:30 PM versus Q1D Dosing Pincus DJ MD, Weeks EE BS, Martin RJ MD, Denver, CO

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277 Linear Growth of Asthmatic Children on Inhaled and Systemic Steroids Kovalhuk LC MD, Rosario NA MD, Lacerda L MD, Gabardo J PhD, Schmidt A MD, Ferrari F MD, Curitiba-Brazil

278 Osteoporosis in Corticosteroid Treated Children Patel P MD, McGeady SJ MD, Philadelphia, PA

279 Effects of Prednisolone on Bone Turnover in Patients with Cortcosteroid Resistant Asthma Lee TH MD, Lane SJ PhD, Sashi V, Swaminathan R MD, London, United Kingdom

280 Individual Variations in Endogenous Cortisoltonus in Normal Population has no Influence on Metabolism in Subcutaneous Adipose Tissue Knutsson U MD, Ekstr0m U MD, BrOnneg6rd M PhD, Ungerstedt U PhD, Werner S PhD, Stierna P PhD, Marcus C PhD, Stockholm, Sweden

281 Delayed Asthmatic Response (DYAR) and Protective Effects of Disodium Cromoglycate (DSCG), Nedocromil Sodium (NDS) and Beclomethasone Dipropionate (BDA) Johansson S-A MD PhD, Miesen WMAJ MD, Pelikan DMV MD, Pelikan Z MD, Breda, The Netherlands

282 Nebulized Nedocromil in the Treatment of Asthma in Young Children Mehra S MD, Oshawa, Ontario, Canada

283 Cost Efficacy of Nedocromil Sodium (NED) Aerosol for Asthma Korenblat P MD, Farrar J PhD, St. Louis, MO; Rochester, NY

284 Steroid Enhancing Effects of Clarithromycin Moy J MD, Raschal S DO, Richmond GW MD, Chicago, 1L

285 Immunomodulation of Roxithromycin for Dermatophagoides farinae (D0-induced IL4, IFN-~/Production in PBMC's from Patients with Bronchial Asthma (BA) Noma T MD, Yoshizawa I PhD, Nakajima T BS, Hayashi M MD, Kawano Y MD, You K MD, Saitama, Japan

286 Effect of Scheduled Albuterol Inhalation on Spirometry, Lung Volumes and Bronchial Hyperreactivity Balson B MD, Ziemke K MD, McGeady SJ MD, Philadelphia, PA

287 Albuterol MDI Cumulative Dose-Response in Asthmatic Children Ferrari FP MD, Ros,irio NA MD, Kantor O MD, Kovalhuk LS MD, Caleffe LG PhD, Curitiba, Brazil

288 Long Term Effect of Fenotero (F) and Fenoterol + Ipratropium Bromide (F+IB) in Asthmatic Children Rocha Jr W MD, Rocha E MD, Wurtz C MD, Duarte R RN, Senna SN MD, Belo Horizonte, Brazil

289 The Effects of IVIG in Severe Steroid-Dependent Asthmic Adults and Adolescents Landwehr LP MD, Jeppson JD MD, Katlan MG MD, Estrel B RN, Hamilos DL MD, Gelfand EW MD, Denver, CO

290 Theophylline Blocks the Spontaneous Release of Nitric Oxide in Vitro in Mononuclear Cells from Asthmatic Patients Sansone G PhD, Matin A MD PhD, Wang SF MS, Bouboulis D MD, Frieri M PhD MD, East Meadow, NY

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The Use of the Internet as a Recruitment Tool for Asthma Drug Development Studies Wiener MB PharmD, Carr S MSCT DMS, Blagg A MA, Denver, CO

A Site Evaluation of a National Ad Recruitment Campaign Kelloway JS PharmD, Peterson S RN, Schoenwetter WF MD, Minneapolis, MN

IMPROVING AND MEASURING ASTHMA OUTCOMES

293 Asthma-Specific Quality of Life in Patients Treated with Salmeterol or Albuterol Cox F PhD, Goodwin B, Wenzel S MD, Rickard K MD, Kalberg C PhD, Emmett A, Research Triangle Parl~ NC

294 Quality of Life and Serum Eosinophil Cationic Protein (ECP) in Asthmatics Col~is C, Lezaun A, Fraj J, Dominguez MA, Duce F, Zaragoza, Spain

295 The Impact of Salmeterol Versus Albuterol on Disease Specific Quality of Life in Mild to Moderate Asthmatics Goodwin B, Cox F PhD, Lumry W MD, Rickard K MD, Kalberg C PhD, Emmett A, Research Triangle Park, NC

296 General Health Status in Rhinitis and Asthma Patients Schoenwetter WF MD, Kelloway JS PharmD, Ireland M PhD, Minneapolis, MN

297 Outcomes Analysis of a Summer Asthma Camp Szelc Kelly C MD, Norfolk, VA

298 Validation of a Pediatric Asthma Diary Santanello NC MD MS, Barber BL PhD, Knorr BA MD, West Point, PA

299 Psychologic Comorbidity in Asthma Lang DM MD, Sherman MS MD, Jaffe JS MD, Verdecchia S RN, Rutigliano P J, Derogatis LR PhD, Philadelphia, PA; Towson, MD

300 Pulmonary Effects of Acute and Chronic Stress During Allergen Exposure Laube BL PhD, Curbow BA PhD, Fitzgerald SM PhD, Spratt K RN MPH, Baltimore, MD

301 Home Bound Asthma Education for Children in Medium Sized Cities: Effectiveness Analysis Prabhakara HS MD, Georgitis JW MD, Althaus AJ MD, Winston-Salem, NC

302 Correct Use of Metered Dose Inhalers/Spacers in a Pediatric Allergy Clinic Brauckmann J MD, Pongracic J MD, Chicago, IL

303 Effects of an Asthma Educational Videocassette for Adults Moscato G MD, Bertolotti G PS, Donner CF MD, Fabbri LM MD, Neri M MD, Rampulla C MD, Zanon P MD, Pavia, Italy

304 Compliance to Peak Expiratory Flow (PEF) Measurements in Long-Term Follow-Up of Asthma C6t~ J, Robichaud P, Boutin H, Lavall6e M, Filion A, Rouleau M, Krausky M, Malo JL, Boulet LP, Cartier A, Quebec, Montreal, Canada

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305 Interventions Lead to Drop in Asthma Hospitalization for Children in Three Kaiser HMOs Plaut TF MD, Stevens MA MD, Weiss-Harrison A MD, Gascoigne CB MD, Tochen ML MD, Amherst, MA

306 Relationship of PEFR to FEV1, FVC, and FEF 25-75 in Adults Lavy RC MD, Annapolis, MD

307 Improving Reading and Language Skills in Inner City Youth is the Key to Asthma Self Management Broussard-Perry D MD, Berger J MS, Nero E BA, Robinson LD MD, Los Angeles, CA

308 Characteristics, Clinical Outcomes and Influence of Education on Asthma Patients with a Poor Compliance to Asthma Treatment Cote J, Boulet LP, Robichaud P, Boutin H, Filion A, Lavallee M, Rouleau M, Krausky M, Malo JL, Cartier A, Quebec, Montreal, Canada

309 Asthma Video Review Bergstrom ARMEd, Jensen KL MA, Li JT MD, Rochester, MN

310 Floating Characteristics of Metered-Dose Inhalers Wolf BL MD, Cochran KR, Anchor JM, Nashville, TN

311 Aerosols: How to Improve Inhalation Technique in Children Larenas DE MD, Huerta JG MD, Mexico City, Mexico

312 Drug Delivery From a Metered Dose Inhaler (MDI) Used with an Inspiratory Flow Control Device (IFCD), Compared to a Spacer Device (SD) Kanter LJ MD, Kanner RE MD, Camarillo, CA; Salt Lake City, UT

MAST CELLS AND BASOPHILS

313 Expression of MHC Class II Molecules on HMC-1 Cells is Upregulated by IFN-7 But Not IL-4 Love KS MS, Lakshmanan RR MS, Butterfield JH MD, Fox CC MD, Columbus, OH; Rochester, MN

314 Mast Cells and T-Lymphocytes in Rheumatoid and Non-Rheumatoid Synovium Nafie AM MD, Fouda E MD, Gruber B MD, Irani AM MD, Schwartz LB MD PhD, Richmond, VA; Long Island, NY

315 Histamine Release from Human Skin Mast Cells by Monocyte Chemoattractant Factor - 1, RANTES, Macrophage Inflammatory Protein - l(x, and Stem Cell Factor Using Microdialysis Technique Petersen LJ MD, Brasso K MD, Pryds M MD, Skov PS PhD, Copenhagan, Denmark

316 Expression of Fas Antigen on a Human and on Murine Mast Cell Lines: Antibody to Fas Antigen Induces Mast Cell Apoptosis Hartmann K MD, Worobec AS MD, Bianchine PJ MD, Mekori YA MD, Metcalfe DD MD, Bethesda, MD

317 Immobilized Serum Amyloid A (SAA) Induces Mast Cell (MC) Adhesion to Extracellular Matrix (ECM) Hershkoviz R MD, Rashkovsky M MS, Lider 0 PhD, Fridkin M PhD, Mekori YA MD, Kfar-Saba, Israel

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318 A Method for Purification of Human Conjunctival Mast Cells Cook E BS, Stahl J PhD, Graziano FM MD PhD, Madison, WI

319 Role of ABC Transporter Proteins in the Release of Leukotriene C4 (LTC4) by Normal Murine Mast Cell Line Nguyen T MD, Gupta S MD PhD, Irvine, CA

320 IgE-Induced PGD2 Release from Cultured Human Mast Cells Nagakura T, Obata T, Yamashita K, Kurosawa M, Masaki T, Maekawa K, Tokyo, Gumma, Japan

321 Induction of Mast Cell Degranulation by Heterotypic Aggregation with T Cells Mekori YA MD, Inamura N PhD, Metcalfe DD MD, Kfar-Saba, Israel; Bethesda, MD

322 Identification of Genes Through a Mast Cell Subtraction Library Vliagoftis H MD, Metcalfe DD MD, Oh CK MD, Bethesda, MD; Los Angeles, CA

323 Importance of Gg Protein Function in Mast Cell Adenosine Receptor Mediated Calcium Mobilization Hoffman HM MD, Marquardt DL MD, La Jolla, CA

324 Type II PLA2 Supplies Arachdionic Acid to PGHS-2 in the Delayed Phase of PGD2 Generation By Mouse Mast Cells Arm JP MD, Murakami M PhD, Bingham III CO MD, Austen KF MD, Boston, MA

325 Integrin-Dependent Histamine Release in Human Basophils: Relationship with Disease Status Goldring K, Hurst K, Djukanovic R, Warner JA, Southampton, United Kingdom

326 Potentiation of Basophil Function by Antibodies to ICAM-3 Saini S MD, White J MAS, Gallatin WM PhD, Hoffman PA PhD, Lichtenstein LM MD PhD, Bochner BS MD, Baltimore, MD," Bothell, WA

327 Expression of Calcium-Dependent and Independent PKC Isozymes in Human Basophils (HB) Miura K MD, MacGlashan DW MD PhD, Baltimore, MD

328 FceR1 13-Subunit Expression is Enhanced by in Vivo Administration of IgE in Rats Marshall JS, Rivera J, Hawlett B, Stead R, Shaikh N, Hamilton, Ontario, Canada; Bethesda, MD

329 Interleukin-4 Enhances and Soluble Interleukin-4 Receptor Inhibits Histamine Release from Peripheral Blood Basophils and Mast Cells In Vitro and In Vivo Renz H, Niggemann B, Zuberbier T, Herz U, Wahn U, Enssle K, Berlin, Behringwerke, Marburg, Germany

330 Expression of Cytokine Genes by Human Mast Cells: Profile, Kinetics and Modulation by Anti-Inflammatory Steroids Lakshman T, Hall K, Smith JK, Huang SK, Krishnaswamy G, Johnson City, TN; Baltimore, MD

331 Naive Human Mast Cells (MC) Transcribe IL-3, IL-5 and GM-CSF mRNA and Secrete IL-5 and GM-CSF Protein Following FceRI Ligation Bressler RB MD, Lesko J, Jones M, Wasserman M, Dickason RR, Cook S PhD, Huston MM PhD, Huston DP MD, Houston, TX

332 Epithelial Inhibition of Mast Cell Activity Peden D MD, Wortman I BS, Dailey L MSPH, Chapel Hill, NC

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333 Lower Enhancing Effect of IL-3 on Basophil Histamine Release in Atopic Than in Nonatopic Subjects Salmaso C MD, Tedeschi A MD, Milazzo N MD, Cottini M MD, Miadonna A MD, Milano, Bergamo, Italy

334 Influence of the Growth Factors NGF and GM-CSF on the Expression of Mast Cell Characteristics Welker P, Grabbe J, Griitzkau A, Henz BM, Berlin, Germany

335 Investigation of Thymus-Derived Factors as Modulators of Basophil Functional Acitivity Gjulling EV MD PhD, Gots TYu MD PhD, Kiev, Ukraine

336 Translocation of 5-Lipoxygenase After IgE-Dependent Activation of Mouse Mast Cells In Vivo Gurish M, Friend DS, Austen KF, Arm JP, Boston, MA

337 Human Recombinant IgE-Dependent Histamine Releasing Factor (HrHRF) Primes Basophils for Histamine Release MacDonald SM MD, Schroeder JT PhD, Langdon JM MS, Jenkens KM, MacGlashan DW MD PhD, Lichtenstein LM MD PhD, Baltimore, MD

338 The Production of MIP-lct by Basophils and its Comparison to the Production by Other Leukocytes Li H MD, Sim T MD, Grant JA MD, Alam R MD PhD, Galveston, TX

339 Serum Secretory Phospholipase A2 Levels in Patients with Mastocytosis Bernton E MD, Hershey J BA, Franson R PhD, Engler R MD, Schwartz L MD, Metcalfe D MD, Worobec A MD, Washington, DC; Richmond, VA; Bethesda, MD

340 Altered Mast Cell Phenotype in Synovial Tissues of Patients with Osteoarthritis Buckley MG PhD, Gallagher PJ MD, Walls AF PhD, Southampton, United Kingdom

341 Mast Cells MCc Expressing Chymase and Not Tryptase Are Induced From Umbilical Cord Blood Progenitors by Conditioned Media From a Mastocytosis Cell Strain, with Kit Ligand Li L MD, Krills SA MD PhD FRACP, Sydney, Australia

342 Csk Associates Directly with GAP-Associated Protein p60 upon FceRI Stimulation Rafnar T PhD, Peebles RS MD, MacGlashan DW MD PhD, Brummet ME BSc, Marsh DG PhD, Baltimore, MD

NEUTRAL PROTEASES

343 Mast Cell Activation in Allergic Rhinitis Can Be Measured by Nasal Fluid Tryptase Rasp G MD, Schwartz LB, Enander I PhD, Munich, Germany; Richmond, VA; Uppsala, Sweden

344 Characterisation of the Two Principal Isoforms of Chymase from Human Skin and Heart McEwen AR PhD, Gaca M MSc, Buckley MG PhD, Davies MJ BSc, Hounsell EF PhD, Gore MG PhD, Walls AF PhD, Southampton, London, United Kingdom

345 Serum o~-Tryptase, an Update on its Use to Screen for Systemic Mastocytosis Carias K MD, Abemathy C MS, Schwartz LB MD PhD, Richmond, VA

346 Expression and Isolation of Non-Glycosylated Recombinant Human (rh) 13-Tryptase Sheikh FR MD, Ren S PhD, Schwartz LB MD PhD, Richmond, VA

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Mast Cell Tryptase Stimulates the Synthesis of Type I Collagen by Human Fibroblasts Cairns JA PhD, Walls AF PhD, Southampton, United Kingdom

Mast Cell Tryptase is a Growth Factor for Human Airway Smooth Muscle Cells Thabrew H BSc, Cairns JA PhD, Walls AF PhD, Southampton, United Kingdom

Serum Tryptase Levels in ICU Patients with Unexplained Acute Hypotension Marshall GD, Calabrese DM, Schwartz LB, Houston, TX,; Richmond, VA

ALLERGIC EFFECTOR MECHANISMS

350 Cyclic AMP-Elevating Agents Prolong the Survival of Human Eosinophils in Culture Hallsworth MP BSc, Giembycz MA PhD, Barnes PJ MD, Lee TH MD, London, United Kingdom

351 Heterogeniety of Human Eosinophils in Response to Platelet Activity Factor and Interleukin-5 Tsai J-J, Wang T-F, Chen P-H, Taipei, Taiwan

352 TNF-ct Prolongs Eosinophil Survival, Partly Through Expression of ICAM-1 Fujisawa T MD, Atsuta J MD, Terada A MD, Iguchi K MD, Kamiya H MD, Sakurai M MD, Tsu, Mie, Japan

353 Spontaneous Survival of Eosinophils and IL-5 Levels in Patients with Idiopathic Hypereosinophilic Syndrome (HES) Kita H MD, Weiler DA MS, Bartemes KR BA, Abrams JS PhD, Gleich GJ MD, Rochester, MN; Palo Alto, CA

354 Mast Cell Sonicates Enhance Eosinophil Survival: a GM-CSF Mediated Effect Levi-Schaffer F PhD, Temkin V BSc, Weg VB PhD, Zilberman Y PhD, Jerusalem, Israel

355 Effects of Protein Kinase Inhibitors on Eosinophil Degranulation Induced By Secretory IgA (slgA) Conjugated Sepharose Beads Ohashi H, Ishikawa M PhD, Kita H, Gleich GJ, Kawai H PhD, Osawa T PhD, Takasaki, Japan; Rochester, MN

356 CD9 - an Activity Marker on Eosinophils in Platelet Containing Blood? Fernvik E BS, Lundahl J MD PhD, GrOnneberg R MD PhD, Halld~n G PhD, Stockholm, Sweden

357 The Expression of Fc),RIII (CD16) on Peripheral Blood Eosinophils Halld6n G PhD, Whelin L PhDs, Fernvik E BS, Lundahl J MD, Stockholm, Sweden

358 Cross-Linking of CD9 Induces Degranulation, GM-CSF Production and Survival of Human Eosinophils Kim J-T MD, Gleich GJ MD, Kita H MD, Rochester, MN

359 Platelet-Activating Factor (PAF) Activates Three Isoforms of Microtubule-Associated Protein (MAP) Kinase in Human Eosinophils Miike S MD, Hiraguri M MD, Iwamoto I MD, Chiba, Japan

360 Mast Cell Sonicates Activate Eosinophils for Cytokine Release: Effect of Dexamethasone Weg VB PhD, Temkin V BSc, Levi-Schaffer F PhD, Jerusalem, Israel

361 Eosinophils Bind to Bronchial Epithelial Cells Fitzpatrick A BS, Crocker IC BS, McGovern M BS, Townley RG MD, Robbins RA MD, Omaha, NE

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362 Eotaxin is an Eosinophil Chemokine Produced by Endothelial and Epithelial Cells and During IL-4 Tumor Suppression Rothenberg ME MD PhD, Garcia E PhD, Leder P MD, Luster AD MD PhD, Boston, MA

363 Eosinophil (EOS) Interaction with ICAM-1 Promotes Release of Superoxide Anion (02-), EOS-Derived Neurotoxin (EDN) and LTC 4 Nagata M, Sedgwick JB, Kita H, Busse WW, Madison, WI; Rochester, MN

364 Eosinophil Adhesion and Degranulation Induced By PMA, GM-CSF and Solid Phase Bound Proteins Reimert CM PhD, Skov PS MD, Poulsen LK PhD, Copenhagen, Denmark

365 Heparin Inhibits RANTES-Induced Chemotaxis of Eosinophils Kuna P MD PhD, Antczak M MD, Cieslewicz G MD PhD, Rozniecki J MD, Lodz, Poland

366 Injection of Histamine with Mast Cell Tryptase Selectively Stimulates Eosinophil Accumulation In Vivo He S MD, Peng Q BM, Walls AF PhD, Southampton, United Kingdom

367 The Cell Surface Antigens CD44 and CD69 are Activation Markers for Human Eosinophils (EOS) Matsumoto K MD, Appiah-Pippim J MD, Bickel C MS, Schleimer RP PhD, Bochner BS MD, Baltimore, MD

368 The Differential Expression of Adhesion Molecules on Airway and Circulating Eosinophils Wong DA MD, O'Byrne PM MD, Hamilton, Canada

369 GM-CSF Regulation in Human Peripheral Blood Eosinophils Horwitz ILl MD PhD, Busse WW MD, Malter JS MD, Madison, WI

370 Eosinophils (EOS) Bind Rhinovirus (RV) via ICAM-1 and Present Antigen to RV-Specific T Cells Handzel ZT, Gem JE, Kelly EAB, Rodriguez RR, Sedgwick JB, Busse WW, Madison, I~I

371 Interleukin-5-Mediated Eosinophilia in Hodgkin's Disease (HD) S~achez-Borges M, Di Biagio E, Desenne J, Su~ez R, Somoza R, Acquatella G, Caracas, Venezuela

372 Mononuclear Eosinophils Developed In Vitro from Hybrid Eosinophil/Basophil Granulocytes Produce GM-CSF Boyce JA MD, Friend D MD, Gurish MF PhD, Austen KF MD, Owen WF MD, Boston, MA

373 Eosinophils Express B7-2 (CD86) and Provide Co-Stimulatory Signals to T Cells For Activation and Proliferation Celestin J MD, Geha RS MD, Boston, MA

374 Nitric Oxide (NO) Production by Human Eosinophils del Pozo V PhD, de Arruda-Chaves E MD, de Andr6s B PhD, C6rdaba B PhD, Gallardo S BS, Jurado A MD, Palomino P PhD, Lahoz C MD PhD, Madrid, Spain

375 Localization of Interleukin-5 (IL-5) mRNA in Eosinophils of Nasal Polyps by In Situ Hybridization Dater I MSc, Bachert C MD, Di~sseldorf, Germany

376 Interferon-y (IFN-y) Suppresses GM-CSF Release From Human Eosinophils (EOS) Shikama Y, Rodriguez R, Sedgwich JB, Kelly EAB, Busse WW, Madison, WI

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Analysis of Recombinant Human Tumor Necrosis Factor-a-Induced CD4 Expression on Human Eosinophils Hossain M MS, Okubo Y MD, Horie S MD, Sekiguchi M MD, Matsumoto, Japan

Eosinophil-T Lymphocyte Interaction: Induction of T Cell Proliferation via CD40 Lim K MD, Geha R MD, Weller PF MD, Boston, MA

Effects of Dexamethasone, Cyclosporine A and Rapamycin on Eosinophil Degranulation and Survival Meng Q, Ying S, Assoufi B, Moqbel R, Kay AB, London, United Kingdom

Increases in Circulating CD34 + Hemopoietic Progenitors in Allergen-Induced Late Asthmatic Responses Sehmi R PhD, Wood L, Watson R, Inman MD MD PhD, O'Bryne PM MB, Denburg JA MD, Hamilton, Ontario, Canada

Chemokine (Ck) Levels in Developing Allergic Skin Late Phase Reactions (LPR) Moskovitz A BS, Reddigari S PhD, Zweiman B MD, Kaplan AP MD, Philadelphia, PA; Stony Brook, NY

Comparison of Inflammatory Events in Skin Sites With and Without Late Phase Allergic Reactions (LPR) von Allmen C BA, Zweiman B MD, Moskovitz A BS, Philadelphia, PA

Cytokine mRNA Positive Cells in Developing Late Phase Reactions (LPR) Zweiman B MD, Anderson W MD, Moskovitz AR BS, Sullivan S BS, Broide DH MD, San Diego, CA; Philadelphia, PA

Sputum Eosinophils and IL-5 in Late Phase Asthmatic Reactions to Antigen Swenson C, Rodriguez R, Kelly EAB, Busse WW, Madison, W1

Inhibitory Activity of Loratadine and Descarboxyethoxyloratadine on Histamine-induced Activation of Human Endothelial Cells Molet S PhD, Gosset P PhD, Vasseur F MD, Czarlewski W MD, Tonnel AB MD, Lille, Levallois-Perret, France

Neuromedin B (NMB) Induces Guinea Pig Nasal Gland Secretion Gawin A, Ali M, Baraniuk JN, Washington, D.C.

INFLAMMATION EFFECTORS, MECHANISMS, MEDIATORS AND THERAPEUTICS

387 Adhesion Protein Expression Does Not Parallel Nasal Eosinophil (EOS) Influx During Persistent Pollen Exposure in Seasonal Allergic Rhinitis (SAR) Zoratti E MD, Meyerson L MD, Benninger M MD, Carey J MD, Swenson C BS, Kelly T, Busse W MD, Detroit, MI; Madison, WI

388 Soluble FceRIct-Subunit in Serum from Allergic and Non-Allergic Patients with Asthma: Immunopurification and Correlation to Disease Activity Bjerke T MD, Christensen M MD, Dahl R MD PhD, Kochan J PhD, Jardieu P PhD, Poulsen LK PhD, Aarhus, Copenhagen, Denmark," Nutley, N J; San Francisco, CA

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389 Soluble a-Subunit (S-a) - A Humoral Form of the High Affinity IgE Receptor is Present in Serum and Nasal Lavages of Allergic Individuals Poulsen LK PhD, Jacobi HH MD, Kochan J PhD, Reimert CM PhD, Skov PS MD PhD, Mygind N MD PhD, Bjerke T MD, Copenhagen, ,~rhus, Denmark; Nutley, NJ

390 Interaction of Allergenic Pollens with Clq and its Significance in Allergic Inflammation Thakur BK MD, Murali MR MD, Ghebrehiwet B PhD, Toledo, OH; Stony Brook, NY

391 Allergen-Specific IgE and IL-5 are Essential for the Development of Airway Hyperresponsiveness (AHR) in a Mouse Model Hamelmann E MD, Oshiba A MD, Schwarze J MD, Bradley K, Loader J, Larsen G, Gelfand EW MD, Denver, CO

392 Mast Cell Chemoattractive Activity in Nasal Lavage From Allergic Patients Nilsson G PhD, Hjertson M BS, Andersson M MD, Nilsson K MD, Siegbahn A MD, Uppsala, Lund, Sweden

393 Comparison of Basophil Releasability in Cord Blood of Newboms Between Healthy Mothers and Asthmatic Mothers Xu YP MD, Zhu LJ MD, Zhu YY MD, Shanghai, China

394 Thl/Th2 Type Cytokine and Major Basic Protein Expression in Lung Explants Following Specific Antigen Challenge In Vitro Minshall E, Dandurand R, Dolman C, Schotman E, Eidelman DH, Hamid QA, Montreal Canada

395 Mast Cells are Not Playing a Role in Eosinophil Accumulation Induced by Allergen In Vivo Kaneko M MS, Schimming AW BA, Bartemes KR BA, Gleich GJ MD, Kita H MD, Kanagawa, Japan," Rochester, MN

396 Regulation of Production of Stem Cell Factor (SCF) by Fibroblasts: Role of Serum Factors Finotto S PhD, Horowitz J PhD, McLaren R PhD, Busse PJ, Metcalfe DD MD, Bethesda, MD

397 Immunolocalization of Stem Cell Factor in Inflamed Human Nasal Tissues Kim YK MD, Nakagawa N MD, Sulakvelidze I MD, Dolovich J MD, Denburg JA MD, Hamilton, Ontario, Canada

398 Evidence for Functional In Vivo Interactions of Human IgE with Murine Effector Cells Herz U PhD, Schnoy N MD, Kolde G MD, Zuberbier T MD, Daser A MD, Renz H MD, Berlin, Germany

399 Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Is Essential for Enhancing Airway Responsiveness in Mice with The Liquid Transformation Product (LTP) of NO 2 Ohta K MD, Miyasaka T MD, Nishizawa M MD, Kubota S MD, Kuwabara M BS, Ito R BS, Ishii A MD, Horiuchi T MD, Mano K MD, Miyamoto T MD, Miyashita H MD, Tokyo, Japan

400 Interferon Gamma (IFN-y) Inhibits Neutrophil Chemotaxis (CTX) Without Affecting Generation of Superoxide Anion (SO) Kowalski ML, Szkudlinska B, Pawliczak R, Iwaszkiewicz J, L6dz, Poland

401 The Effect of Rhinovirus (RV) 16 on Mononuclear Cell Generation of a and y Interferon (INF) Vrtis RF, Dick EC, Gem JN, Busse WW, Madison, WI

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402 Upregulation of Major Histocompatibility Complex (MHC) Molecules and Adhesion Ligands on Respiratory Syncytial Virus (RSV)-Infected Upper Airway Epithelial Cells Saito T MD, Garofalo RP MD, Reyes VE PhD, Ogra PL MD, Galveston, TX

403 Respiratory Syncytial Virus (RSV)-Infected Airway Epithelial Cells Induce Transendothelial Migration of Human Blood Eosinophils Olszewska B MD, Mei F MD, Ogra PL MD, Garofalo RP MD, Galveston, TX

404 The Lung Inflammatory Responses to CC Chemokines -- MCP-1, MCP-3, MIP-I~t and Rantes in Mice Challenged in Vivo Malick A MD, Stafford S BS, Li H MD, Forsythe P BS, Alam R MD, Galveston, TX

405 Relationship Between Urinary Leucotriene E4, Thromboxane B2 and Lung Function (FEV1) Chabane MH MD, Graba S MD, Mounedji N MD, Doudou O MD, Leynadier F MD, Paris, France

406 Sulphidoleukotriene Releasability in Pollinac Patients Ferrer M MD, Sanz ML MD, Prieto I PhD, de Week AL MD, Oehling A MD, Pamplona, Spain

407 The Cellular Antigen-Stimulation-Test (CAST) in the Diagnosis of Hymenoptera Sting Allergy Wiithrich B MD, Maly FE MD, Zurich, Switzerland

408 Allegen Specific IgE Determined by Sanofi-Diagnostic ACCESS® and Pharmacia CAP Kravis B BS, Olson M MT, Nguyen HN, Blumenthal MN MD, Rosenberg A PhD, Minneapolis, MN

409 New Methodologies to Analyze IgG Subclass Distribtution in Specific IgG Response and in IgG/IgE Immune Complexes Allauzen S PhD, Rosenberg A PhD, Larue C PhD, Blocki F PhD, Blumenthal MN MD, Minneapolis, MN

410 New Methodology to Measure Average Affinity of Specific IgG Response in Response in Patients with Allergic Disease Pierson L MS, Allauzen S PhD, Kravis B BS, Daniels L MA, Rosenberg A PhD, Minneapolis, MN

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Total Serum IgD in Atopic Infants and Children E1 Gamal Y MD, Awad Z MD, Zaghloul M MD, Fouad A MS, Cairo, Egypt

The Effects of Inhaled Prostaglandin E 2 on Allergen-Induced Airway Responses Gauvreau GM, Watson RM, O'Byrne PM, Hamilton, Ontario, Canada

413 Urinary Eosinophil Protein X (EPX) in Children with Atopic Asthma: A Useful Marker of Antiinflammatory Treatment Kristjansson S MD PhD, Stannegard I-L MD PhD, Stannegard O MD PhD, Peterson C PhD, Enander I PhD, Wennergren G MD PhD, GOteborg, Uppsala, Sweden

414 Effect of Manganese on Inflammatory Cell Activity Lebel B PhD, Suck C, Bousquet J MD, Campbell AM PhD, Montpellier, Montrouge, France

415 Critical Evaluation of the Histamine Release Assay Hermann K PhD, Donhauser S MD, Ring J MD PhD, Munich, Germany

416 Effects of Allergy/Asthma Drugs on IgE Synthesis Broome CB MD, Buckley RH MD, Durham, NC

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417 Effect of the Leumedin N-(Fluorenyl-9-Methoxycarbonyl)-L-Leucine (FMOC-Leu) on Eosinophil Function Salata KF PhD, Hershey JN BA, Alford RG MSc MT(ASCP), Washington, DC

418 Inhibition of Sodium, Potassium Adenosine Triphosphatase (Na+, K+ ATPase) Downregulates Proliferation of Peripheral Blood Mononuclear Cells (PBMNC) and Subsets Patel A BS, Gentile D MD, Skoner D MD, Pittsburgh, PA

419 In Vivo and In Vitro Studies of Leukotrienes in Asthmatic Children Before and After Different Therapeutic Modalities EI-Morsy Z MD, E1-Shennawy MD, Shaltout A MD, Zedan M MD, Mansoura University, Egypt

420 Effects of Nedocromil Sodium (NDS) on the Immediate Nasal Response to Allergen Challenge (INR) and the Accompanying Cellular Changes in the Nasal Secretions (NS) Pelikan Z MD, Trimbach YA MD, Pelikan-Filipek M MD, Breda, The Netherland

421 Effects of Drugs on Expression of Adhesion Molecule on Cytokine-Stimulated Human Eosinophils Momose T MD, Okubo Y MD, Hossain M MS, Horie S MD, Sekiguchi M MD, Matsumoto, Japan

422 Effect of Theophylline and Procaterol on Degranulation and Surface Antigen Expression of Human Eosinophils Okubo Y MD, Horie S MD, Hossain M MS, Sekiguchi M MD, Matsumoto, Japan

423 Effects of Mometasone Furoate and Other Glucocorticoids on Cytokine Production from Cultured Peripheral Blood CD4+ T Cells Umland SP PhD, Nahrebne DK MS, Razac S BS, Billah MM PhD, Egan RW PhD, Kenilworth, NJ

424 Propranolol Enhances Histamine and Interleukin-5 Generation from Anti-IgE Challenged Human Lung Fragments: Evidence for Inverse Agonist Effect Remy FJ MD, Jaffe JS MD, Raible DG MD, Post TJ, Wang Y, Glaum M, Schulman ES MD, Philadelphia, PA

425 Effect of the Lazaroid U-89843D on Allergen-Induced Bronchial Hyperresponsiveness and Pulmonary Eosinophilia in an Allergic Rabbit Model of Asthma Aktaruzzaman M, Gregg L, Metzger W J, Greenville, NC

426 The Cysteinyl-Leukotriene (CysLT) Receptor Antagonist, Pranlukast, Attentuates Airway Inflammation Underwood DC PhD, Bochnowicz S BS, Osborn RR BS, Newsholme SJ DVM, Torphy TJ PhD, Hay DWP PhD, King of Prussia, PA

427 Glucocorticoids Inhibit Leukotriene Release by Mixed Leukocytes Crocker IC MSc, Zhou C-Y MD, Kreutner W PhD, Bewtra AK MD, Townley RG MD, Omaha, NE

428 Fluticasone Propionate (FP) Attenuates the Release of RANTES and slCAM-I From Human Bronchial Epithelial Cells (HBEC) In Vitro Devalia JL PhD, Wang JH MD, Sapsford RJ MIST, Davies RJ FRCP, London, United Kingdom

429 Immunomodulatory Efficacy of Selective Phosphodiesterase (PDE) Inhibitors on Antigen-Specific T Cell Clones (TCC) Essayan DM MD, Kagey-Sobotka A PhD, Lichtenstein LM MD PhD, Huang S-K PhD, Baltimore, MD

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Suppression of Eosinophil Function by Suplatast Tosilate Terada A MD, Fujisawa T MD, Atsuta J MD, Iguchi K MD, Kamiya H MD, Sakurai M MD, Tsu, Mie, Japan

Antiallergic Activity of Azelastine Eye Drops Ciprandi G, Buscaglia S, Catrullo A, Pesce GP, Fiorino N, Montagna P, Bagnasco M, Canonica GW, Genoa, Italy

A Sodium, Potassium Adenosine Triphosphatase Inhibitor (Na +, K + ATPase INH) in Bronchoalveolar Lavages (BAL) of Asthmatics Following Segmental Allergen Challenge (SAC) Gentile D MD, Ollila C, Calhoun W MD, Skoner D MD, Pittsburgh, PA

INDUCTION OF ALLERGY

433 Chimeric Proteins Expressed by Recombinant DNA and a Synthetic Oligopeptide Represent a Dominant Antigenic Determinant of Par o 1 for Human IgG and IgE Antibodies Cassese G, Menna T, Chersi A, di Modugno F, Ruffilli A, Naples, Rome, Italy

434 IgE-Reactivity of Recombinant Grass Pollen Allergens Expressed in the Yeast Pichia pastoris Suphioglu C PhD, Singh MB PhD, Knox RB PhD, Melbourne, Australia

435 Adult Onset Hyper-IgE Syndrome (HIES), Eosinophilia and Dermatitis, Associated with Lack of CD3 Expression on CD4 Lymphocytes Reshef A MD, Shemer A MD, Bank I MD, Levi-Schaffer F PhD, Tel-Hashomer, Jerusalem, Israel

436 Expression of Trichophyton Proteins in Culture: Relevance to Skin Test Extracts Woodfolk JAMB ChB, Slunt JB BS, Platts-Mills TAE MD PhD, Charlottesville, VA

437 ICAM-1 Expression and Regulation on 3 Epithelial Cells: Relevance for Allergic Inflammation Bagnasco M, Paolieri F, Pesce GP, Battifora M, Riccio AM, Ciprandi G, Canonica GW, Genoa, Italy

438 GM-CSF Increases Cytosolic Free Calcium (Ca2+i) and Ciliary Beat Frequency (CBF) of Cultured Tracheal Ciliated Epithelial Cells Park CL MD, Dong T BS, Mao H MD PhD, Wong LB PhD, Chicago, IL

439 Phenotyping and Cytokine Regulation of the Human Bronchial Epithelial Cell Line BEAS-2B Atsuta J MD, Bochner BS MD, Sterbinsky SA MS, Schleimer RP PhD, Baltimore, MD

440 Eosinophil Peroxidase Stimulates the Release of Granulocyte-Macrophage Colony-Stimulating Factor from Respiratory Epithelial Cells Motojima S MD, Adachi T MD, Arima M MD, Manaka K PhD, Fukuda T MD, Makino S MD, Tochigi, Japan

441 RANTES Production in Cultured Human Conjunctival Epithelial Cell Line Fukagawa K MD, Saito H MD PhD, Tachimoto H MD, Kimata M BS, Oguchi Y MD PhD, Iikura Y MD PhD, Tokyo, Japan

442 Patchy Epithelial Damage/Restitution Processes at Allergen Challenge-Induced Airway Inflammation Persson CGA, Erjef~ilt JS, Korsgren M, Nilsson M, Sundler F, Lund, Sweden

443 The Expression of Lymphocyte Chemoattractant Factor (LCF) in Human Brochial Epithelial Cells Arima M MD, Plitt JR BS, Stellato C MD, Schwiebert LM PhD, Schleimer RP PhD, Baltimore, MD

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444 Whole Body Plethysmography (WBP) in Mice Detects Airway Sensitization Through Changes in Lower Airways Function Schwarze J MD, Hamelmann E MD, Larsen G MD, Gelfand EW MD, Denver, CO

445 Antigen Induced Plasma Protein Leakage in the Lungs of Sensitized Brown Norway Rats Taylor BM MS, Kolbasa KP BS, Chin JE PhD, Richards IM PhD, Sun FF PhD, Kalamazoo, MI

446 Increased Permeability of the Respiratory Membrane Four Hours After Segmental Allergen Challenge Nocker RET, Weller FR, de Riemer M J, Traanberg KF, Out TA, Jansen HM, van der Zee JS, Amsterdam, The Netherlands

447 Asymptomatic Lymphoma in a Patient with Extreme IgE Elevation Koutsonikolis A MD, Day NK PhD, Chamizo W MD, Good RA PhD MD DSc, Kornfeld SJ MD, St. Petersburg, FL

448 The Relationship Between CD23 and IgE in Atopics and Non-Atopics Nejat M MD, Haralabatos I MD, Mazza DS MD, Meriney DK MD, Reddy M PhD, Cleveland L PhD, Grieco MH MD, New York, NY

449 Study of SCD23 and Total IgE Level in Serum of Atopic Groups Farid R MD, Sedaghatnia R MS, Masood A MD, Tehran, Mashhad, Iran

450 Antigen Stimulated Cytokine Synthesis, Specific lgE and Clinical Sensitivity to Cats are Directly Related Fitzpatrick-Wong S BS, Imada M MD PhD, Simons FER MD, Peng Z MD, Simons KJ PhD, HayGlass KT PhD, Winnipeg, Canada

451 IgE and IgG4 Specific Antibodies to Dactylis Glomerata Allergens Correia S PharmD, Martins LM DVM, Peres MJ PharmD, Costa H BS, Meisel ML PhD, Desvaux F MD, Peltre G PhD, In~cio F MD, Set~bal, Portugal

452 Lack of Specificity of B7 Homologues in Human Thl and Th2 Responses Bashian GG, Braun CM BA, Kagey-Sobotka A PhD, Lichtenstein LM MD PhD, Huang SK PhD, Essayan DM MD, Baltimore, MD

453 Effects of an Antibody to Interleukin-5 in a Murine Model of Airway Sensitization Gelfand EW MD, Schwarze J MD, Oshiba A MD, Bradley K, Loader J, Larsen G MD, Coffman R PhD, Hamelmann E MD, Denver, CO; Palo Alto, CA

454 Dendritic Cells and B Cells in rDer p2 Presentation to Memory and Naive T Cells From Atopic Patients Taketomi EA MD PhD, Sung SJ PhD, Slunt JB BSc, Smith AM PhD, Platts-Mills TAE MD PhD, Fu SM MD PhD, Charlottesville, VA; Uberlandia, MG, Brazil

455 TT, A Cells And Parameters of Allergic Disease: Relationship to Total IgE, Atopy, and Basophil Histamine Release Volkman D J, Kuna P, Kuna E, Kaplan AP, Lodz, Poland," Stony Brook, NY

456 Depletion of Neutrophils Promotes T Helper 2 Cytokine Pathway in Murine Allergic Aspergillosis Murali PS PhD, Guo J MS, Xia JO MD, Coffman RL PhD, Kurup VP PhD, Milwaukee, WI; Palo Alto, CA

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IFN-y Treatment Results in the Functional Alteration of Antigen-Specific CD4 + T Cells Lack G MD, Kupfer A MD, Oshiba A MD, Hamelmann E MD, Bradley KL, Kupfer H MD, Loader J, Larsen G, Gelfand EW MD, Denver, CO

Increased Bone Marrow Progenitor Growth After Allergen Challenge in Dogs Depends on a Serum Factor Inman MD MD PhD, Ellis R, Wattie J, Lane CG, D/thlback M PhD, Denburg JA MD, O'Byrne PM MB, Hamilton, Canada," Astra Draco, Sweden

Effect of Acellular Pertussis Vaccine (APV) on the Development of Allergic Sensitization to Environmental Allergens Assa'ad AH MD, Sebastian K, Lierl MB MD, Cincinnati, OH

Local Control of e-Gene Expression in B Cells of the Nasal Mucosa in Hay Fever Patients Following Allergen-Challenge Durham SR, Gould H J, Thienes CP, Jacobson MR, Masuyama K, Rak S, Lowhagen O, Schotman E, Hamid Q, London, United Kingdom; Gothenburg, Sweden; Montreal, Canada

Distribution of Plasma Cell Markers and Intracellular IgE in the Cell Line U266 Lagging E BS, van Hage-Hamsten M MD, H/trfast B PhD, Halld6n G PhD, Stockholm, Sweden

Cytokine Production by Peripheral Blood Mononuclear Cells (PBMCs) and Allergen-Specific T Cell Clones in Atopic Individuals Hong S J, Choi Y J, Oh SH, Shim Y J, Choi SW, Moon HB, Seoul, Korea

rhGM-CSF Promotes an Antigen-Presenting Phenotype in Human Macrophages Caulfield JJ BSc, Kemeny DM PhD, Lee TH MD, London, United Kingdom

CD4 + But Not CD8 + T Cells Transfer Allergic Airway Hyperresponsiveness (AHR) in BN-Rats Haczku A MD, MacAry P, Huang D MD, Tsukagoshi H MD, Barnes PJ MD, Kay AB MD, Kemeny DM PhD, Chung KF MD, Moqbel R PhD, London, United Kingdom

Modulation of Antigen-Dependent B and T Cell Responses by Antigen-Specific IgE Antibody Oshiba A MD, Haczku A MD, Hamelmann E MD, Takeda K MD, Bradley K BS, Conrad D MD, Kikutani H MD, Gelfand EW MD, Denver, CO; Richmond, VA; Osaka, Japan

Interleukin-2 is Produced by Both Thl and Th2 Cells Foster B MS, Prussin C MD, Metcalfe DD MD, Bethesda, MD

ORAL PRESENTATION SYMPOSIA SUNDAY, MARCH 17, 1996

3:00 PM TO 5:00 PM

UNDERSTANDING THE MECHANISMS AND CLINICAL VARIABLES OF NASAL DISEASE Moderators: James Baraniuk, M.D. and David Proud, M.D.

467 3:12 pm Increased Levels of Interleukin-l, Interleukin-6, Interleukin-8, Soluble Intercellular Adhesion Molecule, and Bradykinnin are Detected in Nasal Secretions of Patients During Naturally Acquired Rhinovirus Colds HOpken KL MD, Hillebrandt MH MD, ROseler ST MD, Bachert C MD, Di~sseldorf, Germany

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468 3:24 pm Natural History of Hay Fever: A 23-Year Follow-Up of College Students Greisner III WA MD, Settipane RJ MD, Settipane GA MD, Providence, RI

469 3:36 pm In Utero Sensitisation of the Human T-cell System to Aeroallergens Prescott SL MB BS BMedSci, Sly P MD, Loh RKS MBBS, Holt B BSc, Holt P DSc, Perth, Australia

470 3:48 pm Interleukin-5 Protein and mRNA are Increased in Nasal Polyps Wagenmann M MD, Diiter I, Rudack C MD, Ganzer U MD, Bachert C MD, DUsseldorf Germany

471 4:12 pm Effect of a Topical Nasal Steroid on GM-CSF, IL-6, IL-8 and HLA-D Expression by Nasal Epithelial Ceils in Seasonal Allergic Rhinitis (SAR) Sulakvelidze I, Nakano K, Conway M, Edney P, Brattsand R, Duku E, Goldsmith C, Dolovich J, Hamilton, Ontario, Canada

472 4:24 pm Nasal yA- T Cells in Perennial Allergic Rhinitics Express the CD40L and Induce IgE " Synthesis Pawankar R MD, Okuda M MD, Wada N MS, Azuma M MD, Okumura K MD, Ra C MD, Tokyo, Japan

473 4:36 pm Hypertonic Saline Bronchial Challenge (HSC) in Normal (N), Allergic Rhinitis (AR) and Asthmatic (A) Subjects. A Comparison with Methacholine Challenge (MC). An Update Townley RG, Romero FA, Williams P, Pinnas J, Rosenthal R, Ford L, Omaha, NE

474 4:48 pm Local Nasal Immunotherapy (LNIT) with Aqueous Weed Extract is an Effective Therapy for Weed Induced Rhinitis Gaglani B MD, Borish L MD, Buchmeier A, Keller L MA, Nelson H MD, Denver, CO

AIRBORNE ALLERGEN CONTROL Moderators: Robert Wood, M.D. and Peter Heymann, M.D.

475 3:12 pm Absolute Quantitation of Mite Allergen-Specific IgE Antibody Levels by ELISA Using a Chimeric Mouse Fab/Human Fc Epsilon Antibody to Der p 2 Elderfield AJ PhD, Schuurman J BSc, Aalberse R PhD, Smith A MD, Woodcock A MD, Chapman MD PhD, Manchester, United Kingdom; Amsterdam, The Netherlands; Charlottesville, VA

476 3:24 pm Allergens in Inner City Homes Eggleston P MD, Baltimore, MD

477 3:36 pm Evaluation of Cockroach Allergens in Low Income Housing: Bla g 1 & Bla g 2 Only Airborne During Disturbance Mollet J PhD, Perzanowski M BA, Avner D BS, Arruda LK MD PhD, Chapman M PhD, Platts-Mills TAE MD PhD, Charlottesville, Blacksburg, VA

478 3:48 pm Major Dog Allergen Can f 1: Distribution in Homes, Airborne Levels and Particle Sizing Custovic A MD, Green R MD, Pickering CAC MD, Smith A MD, Chapman MD PhD, Woodcock A MD, Manchester, United Kingdom

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480 4:24 pm

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482 4:48 pm

Avoidance of Dog Allergen Can f 1 with the Dog In Situ: Washing the Dog and Use of a HEPA Air Filter Green R MD, Custovic A MD, Smith A MD, Chapman MD PhD, Woodcock A MD, Manchester, United Kingdom

"Drawing the Line" - Rapid Diagnostic Testing (RDT) for Detection of Dust Mite, Cat and Cockroach Allergens Chapman MD PhD, Williams L PhD, Chandler J PhD, Manchester, Cardiff, United Kingdom

Reduction of Exposure to Laboratory Animal Allergens Gordon S PhD, Wallace J, Welch JA, Cook A MSc, Jones M PhD, Tee RD PhD, Newman Taylor A J, London, Sutton, Surrey, United Kingdom

Endotoxin Levels in Various House Dust Samples Williams PB PhD, Lenexa, KS

ROLE OF CYTOKINES IN REGULATION OF ALLERGIC INFLAMMATION Moderators: Peter Weller, M.D. and Robert Schleimer, Ph.D.

483 3:12 pm GM-CSF Regulates the Functional Adhesive State of VLA-4 Expressed by Eosinophils Broide DH MD, Yang L, Elices M PhD, Jin G, Sriramarao P PhD, Sung K-LP PhD, San Diego, CA

484 3:24 pm IL-13 But Not IL-4 Prolongs Eosinophil Survival and Induces Eosinophil Chemotaxis Horie S MD, Okubo Y MD, Hossain M MS, Sato E MD, Nomura H MD, Koyama S MD, Sekiguchi M MD, Matsumoto, Japan

485 3:36 pm Induction of Lymphotactin Gene Expression in Mast Cells Following FceRI Aggregation: Modulation by TGF-fl, IL-4 and Dexamethasone Rumsaeng V MD, Vliagoftis H MD, Oh C MD, Nagata H MD PhD, Metcalfe DD MD, Bethesda, MD

486 3:48 pm Interleukin-5 Induces Activation of the Phosphotyrosine Phosphatase, SHPTP2 (Syp) in Eosinophils Pazdrak K MD, Alam R MD PhD, Galveston, TX

487 4:12 pm A Novel C-C Chemokine, CKI310 is Expressed in Airway Epithelial Cells and is a Potent Eosinophil Chemoattractant Stellato C MD, Beck L MD, Schwiebert L PhD, Li H PhD, White J PhD, Schleimer RP PhD, Baltimore, Rockville, MD; King of Prussia, PA

488 4:24 pm Epithelial Cells are the Major Cellular Source of Eotaxin mRNA in the Guinea Pig Lung Stahl J PhD, Cook E BS, Rothenberg M MD PhD, Graziano FM MD PhD, Madison, WI; Boston, MA

489 4:36 pm Respiratory Syncytial Virus-Induced Release of RANTES and MIP-hx by Bronchial Epithelial and Peripheral Mononuclear Cells Siddiqi A MD, Peeples M PhD, Brees A BS, Moy J MD, Chicago, IL

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490 4:48 pm The Expression of CC Chemokines in the Lung in an Allergic Model of Airway Inflammation Alam R, Stafford S, Li H, Bravo R, Galveston, TX," Princeton, NJ

THEMATIC POSTER SESSION MONDAY, MARCH 18, 1996

8:30 AM TO 11"30 AM

ASTHMA DISEASE PATHOGENESlS

491 Analysis of Superoxide Production by Ovine Alveolar Cells Before and After Infection with RSV Bacot BK MD, Abramson SL MD PhD, Hiatt PW MD, Piedra AA MD, Shearer WT MD PhD, Houston, TX

492 Association Between Nasal slGA to Chronic Chlamydia Pneumoniae Infection and Asthma Exacerbations in Children Cunningham A, Johnston SL, Julious SA, Lampe FC, Ward ME, Southampton, United Kingdom

493 Markers of Inflammation in Induced Sputum in Acute Bronchitis Caused by Chlamydia Pneumoniae Pizzichini MMM, Efthimiadis A, Clelland L, Pizzichini E, Evans S, Mahony J, Dolovich J, Hargreave FE, Hamilton, Ontario, Canada

494 Airway Pathology After Viral Antigen Challenge in Rats After Antecedent Viral Illness Kaplan M BS, Sorkness R PhD, Stokes J MD, Castleman WL DVM PhD, Gem JE MD, Lemanske Jr RF MD, Madison, WI

495 Effect of Experimental Rhinovirus 39 (RV-39) Infection on Nasal Bradykinin (BK) Levels Skoner D MD, Doyle W PhD, Seroky J MA, Fireman P MD, Cohen S PhD, Kaplan AP MD, Shibayama Y PhD, Pittsburgh, PA; Stony Brook, NY; Japan

496 The Role of Chlamydia pneumoniae in Reversible Obstructive Airway Disease Simon FT MD, Nelson HS MD, Noda JA, Routes JM MD, Denver, CO

497 Effect of Hanks Rhinovirus (RV-H) Infection on the Lower Airways in Allergic Rhinitis (AR) and Non-AR Subjects Van Deusen M BS, Angelini B RN BSN, Doyle WJ PhD, Seroky J MA, Cohen S PhD, Skoner DP MD, Pittsburgh, PA

498 Patterns of Respiratory Virus Infections and its Association with Acute Childhood Asthma Chew FT BSc, Doraisingham S MD, Goh DYT MD, Kumaransinghe G MD, Ooi BC MD, Lim YL, Soh SY, Lee BW MD, Singapore, Singapore

499 Cellular Inflammation in the Airways in Asthma Compared with Bronchiectasis Bentley AM, Gaga M, Barkans J, Humbert M, Wathen CG, Kay AB, Durham SR, Oxford, London, United Kingdom

500 Comparison of Inflammatory Cells in Sputom, Bronchoalveolar Lavage (BAL) and Bronchial Biopsies in Asthma and Chronic Bronchitis Maestrelli P MD, Saetta MD, DiStefano A PhD, Calcagni P MD, Turato G PhD, Mapp CE MD, Fabbri LM MD, Padova, Ferrara, Italy

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501 Expression of Activation Markers on Alveolar Marcophages (AM) in Allergic Asthmatics After Endobronchial (EB) or Whole Lung (WL) Allergen Challenge Viksman MY MD, Bochner BS MD, Liu MC MD, Schleimer RP PhD, Baltimore, MD

502 High Affinity IgE Receptor (FceRI)-Bearing Cells in Bronchial Biopsies from Atopic and Non-Atopic Asthma Barkans J, Grant JA MD, Taborda-Barata L MD, Ying S PhD, Menz G MD, Pfister R MD, Durham SR MD, Kay AB MD, Humbert M MD, Galvetson, TX; Davos-Wolfgang, Sweden," United Kingdom

503 A Comparison Between Airway Resistance and Cellular Responses in Bronchoalveolar Lavage Fluid (BALF) and in Lung Interstitium (LUNG) in Cockroach Allergic Guinea Pigs Zhou D MD, Miller B MD, Gindling H MS, Profitt R BS, Sajadi K BS, Kang BC MD, Lexington, KY

504 Safety of Bronchscopy in Asthmatics and Control Subjects and Effect on Asthma Control Over Two Weeks Robinson DS MD, Humbert M MD, Assoufi B PhD, Kay AB PhD, Durham SR MD, London, United Kingdom

505 Analysis of T Cell Receptor Clonotypes in Bronchoalveolar Lavage Fluids of Nonatopic Asthmatics Umibe T MD, Kita Y MD, Nakao A MD, Nakagawa N MD, Fukuda T MD, Makino S MD, Iwamoto I MD, Chiba, Tochigi, Japan

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Release of GM-CSF from Cultured Epithelial Cells Stimulated with Sputum from Patients with Asthma Adachi T MD, Motojima S MD, Manaka K PhD, Arima M MD, Fukuda T MD, Kihara N MD, Makino S MD, Tochigi, Japan

Secretory Phospholipase A 2 is Elevated in Lung Lavage Fluid after Antigen Sensitization in Asthmatic Guinea Pigs Sane AC, Mendenhall T, Bass DA, Winston-Salem, NC

508 Specific IgE Antibodies in Serum and in Bronchoalveolar (BAL) Fluid Correlate with the Magnitude of the Antigen-Induced Late Phase Reaction Peebles Jr RS MD, Hamilton RG PhD, Lichtenstein LM MD PhD, Schlosberg M MD, Liu MC MD, Togias A MD, Baltimore, MD

509 Bronchoalveolar Lavage (BAL) Cellularity in Asthmatic Children and Infantile Wheezers: Role of Neutrophils Marguet C MD, Jouen F MD, Lees O MD, Mallet E MD, Dean TP PhD, Warner JO MD, Rouen, France; Southampton, United Kingdom

510 Assay of ABO(H) Erythrocyte Antigen by Hemagglutination Inhibition of Murine Monoclonal Anti-A and Anti-B Antibodies Bukantz SC MD, Calderon E MD, Lockey RF MD, Tampa, FL

511 Use of Eosinophil Cationic Protein as a Predictive Marker for Exacerbations of Asthma McGill KA PharmD, Sorkness CA PharmD, Lanner A, Swenson C BS, Busse WW MD, Madison, WI; Uppsala, Sweden

512 Bronchial Mucosal Gene Expression of the CC Chemokines RANTES and MCP in Symptomatic Atopic and Non-Atopic Asthma: Relationship to Eosinophil-Active Cytokines IL-5, GM-CSF and IL-3 Humbert M MD, Ying S PhD, Menz G MD, Barkans J, Pfister R MD, Corrigan C MD, Durham SR MD, Kay AB MD, London, United Kingdom; Davos-Wolfgang, Germany

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513 Sputum Cellular and Fluid Phase Components: Comparison of the Effect of Dithiothreitol vs. Phosphate Buffered Saline Efthimiadis A, Pizzichini MMM, Weston S, Pizzichini E, Evans S, Dolovich J, Hargreave FE, Hamilton, Ontario, Canada

514 Eosinophils (Eo) and ECP of Induced Sputum Compared with Peripheral Blood (B) Pizzichini E, Pizzichini MMM, Efthimiadis A, Evans S, Dolovich J, Hargreave FE, Hamilton, Canada

515 Eosinophil Cationic Protein (ECP) in Cystic Fibrosis (CF) Jacques IM MD, Selden R MD, Rakes GP MD, Huston DP MD, Platts-Mills TAE MD PhD, Heymann PW MD, Houston, TX; Charlottesville, VA

516 Platelet-Activating Factor (PAF)-Induced Eosinophil Degranulation Requires Tyrosine Phosphorylation Agrawal DK PhD, Omaha, NE

517 Nasal Eosinophil Cationic Protein and Urinary Protein X as Markers of Asthma Neuparth N MD PhD, Gamboa T MD, Ribeiro da Silva I, Carvalho H, Trindade H MD, Rosado Pinto JE MD, Rendas AB MD PhD, Lisbon, Portugal

518 Comparative Studies of Specific Bronchial Provocation Tests with Two Differently Standardized Dpt Allergens Siergiejko Z MD, Zietkowski Z MD, Chyrek-Borowska S PhD MD, Bialystok, Poland

519 Relationship Between Bronchial Hyperresponsiveness to Cold Air (BHR), Eosinophilic Cationic Protein (ECP) and IgE Levels to Dermatophagoides pteronyssinus in Asthmatic Patients Greiding L, Cortigiani LD, Josviack D, Moreno P, Flores D, Paulin P, Grinstein M, Buenos Aires, Argentina

520 Sialyl Lewis x Analog Suppresses Eosinophil Accumulation and Late Asthmatic Response in a Guinea Pig Model of Asthma Sagara H MD, Ra C MD, Okada T MD, Ishikawa A MD, Sakumi S, Fukuda T MD, Okumura K MD, Makino S MD,

521 A Monoclonal Antibody Against PAF Receptor Inhibits Allergic Reaction Okada T MD, Sagara H MD, Ishikawa A MD, Nakada T, Fukuda T MD, Okumura K MD, Ra C MD, Makino S MD, Tochigi, Japan

522 Both Lymphocytes and Monocytes Contribute to the Enhanced Tumour Necrosis Factor-a (TNF-tx) Production by Peripheral Blood Mononuclear Cells (PBMC) of Severe and Mild Atopic Asthmatics Waserman S MD, Dolovich J MD, Bryk J, Marshall JS PhD, Hamilton, Ontario, Canada

523 Relationship of Bronchial Mucosal IL-5 mRNA Expression with Disease Severity and IL-4 mRNA Expression with Serum IgE Concentrations in Atopic and Non-Atopic Asthmatics Corrigan C MD, Humbert M MD, Durham SR MD, Kimmitt P, Ying S PhD, Barkans J, Robinson DS, Assoufi B, Pfister R MD, Menz G MD, Kay AB MD, London, United Kingdom; Davos-Wolfgang, Germany

524 Increase in Interleukin-16 (IL-16) Expression in Baseline Asthma Laberge S, Ernst P, Ghaffar O, Song YL, Cruikshank WW, Center DM, Hamid Q, Montreal, Quebec, Canada; Boston, MA

525 Endogenous Kinins are Formed in Airways During Plasma Extravasation Induced by Leukotriene D4 Kawikova I MD, Arakawa H MD PhD, Skoogh BE MD PhD, L6tvall J MD PhD, G6teborg, Sweden

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Bronchoconstriction Induced by Bradykinin: Attenuation by Inhaled L-ASA in Asthmatic Subjects Crimi N, Polosa R, Milazzo VL, Santonocito G, Prosperini G, Ciamarra I, Mistretta A MD, Catania, Italy

Indoor and Outdoor Allergen-Stimulated Interleukin 8 Production in Asthma Therattil J MD, Zitt M MD, Bouboulis D MD, Wang SF MS, Sansone G PhD, Castro J BS, Frieri M MD PhD, East Meadow, NY

Interleukin-4 and Interferon-Gamma mRNA Expression in Minor Salivary Glands in Bronchial Asthma Tsicopoulos A MD, Janin A MD, Vorng H, Tonnel AB MD, Wallaert B MD, Lille, France

Increased c-fos Synthesis in Mononuclear Cells from Patients with Corticosteroid Resistant Asthma Lane SJ MD PhD, Adcock IM PhD, Barnes PJ MD, Lee TH MD, London, United Kingdom

BRONCHIAL HYPERREACTIVITY

530 Bronchial Hyperresponsiveness (BHR) in Patients with Symptoms of Gastroesophageal Reflux Disease (GERD) Hinze SG, Rosemeyer D, Bad Driburg, Germany

531 Nasal Cold, Dry Air (CDA) Challenge Results in Stronger Nasal and Pulmonary Responses in Asthmatics Compared to Patients with Rhinitis Stephens L, Proud D PhD, Togias A MD, Baltimore, MD

532 rhuMAb-E25 (E25), Humanized Murine Monoclonal Anti-IgE, Inhibits the Allergen-Induced Early Asthmatic Response (EAR) Cockcroft DW, Kalra S, Bhagat R, Swystun VA, Boulet LP, Cote J, Laviolette M, Deschesnes F, Chapman KR, Cleland LD, Fick RB, Su J, DeVault A, Saskatoon, Quebec City, Toronto, Canada," San Francisco, CA

533 Occasional Wheezing in Children is not Always Associated with Bronchial Hyperresponsiveness (BHR) Roizin H MD, Reshef A MD, Benzaray S MD, Shiner RJ MD, Tel-Hashomer, Israel

534 Dose-Response of Inhaled Beclomethasone (B) for Attenuating the Airway Responses to Allergen Marshik PL PharmD, Thomas D MD, Ahrens R MD, Braver H MD, Hendeles L PharmD, Gainesville, FL; Iowa City, IA

535 Effect of Cetirizine on Bronchial Hyperresponsiveness in Patients with Allergic Rhinitis Aubier M, Neukirch C, Melac M, Paris, France

536 A Comparison of the Effects of Oral Cetirizine and Inhaled Beclomethasone on Early and Late Asthmatic Responses to Allergen and the Associated Increase in Airway Responsiveness Walker SM, Bentley AM, Hanotte F, de Vos C, Durham SR, London, United Kingdom; Belgium

537 Spontaneous Recovery from Methacholine (Mch)-Induced Bronchoconstriction: A Test to Assess Asthma Severity Livas I MD, Peebles Jr RS MD, Brennan F BS, Togias A MD, Baltimore, MD

538 Confluence Determines the Effect of Hyperoxic Injury on MDCK Epithelial Cells and Antioxidant Vitamin Protection Jyonouchi H MD, Sun S DDS, Mizokami M BS, Ingbar DH MD, Minneapolis, MN

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539 Bronchial Hyperreactivity in Patients with Atopic Dermatitis without Asthma Symptoms Comparing with Those Atopic Dermatitis Patients and Asthma Symptoms, Using Methacoline Challenge Test Gazca-Aguilar A MD, Del Rio-Navarro B, Sienra-Monge J J, Mexico City, Mexico

MASQUERADERS OF ALLERGIC DISEASE

540 Aspirin Desensitization/Treatment of Aspirin Sensitive Rhinosinusitic-Asthmatic Patients: Long Term Outcomes Stevenson DD, Hankammer MA, Mathison DA, Christiansen SC, Simon RA, La Jolla, CA

541 RANTES Levels and Eosinophils Increase in Bronchoalveolar Lavage Fluid (BALF) after Indomethacin in Aspirin-Intolerant Asthmatics (AIA) Warren MS MD, Sloan SI BS, Trudeau JB BS, Hoffman NE BS, Westcott JY PhD, Wenzel SE MD, Denver, CO

542 Expression of COXl and COX2 on Aspirin-Sensitive (ASA) and Non-Aspirin-Sensitive (NASA) Asthmatic and Normal Bronchial Mucosa Sousa AR BSc, Pfister R PhD, Lane SJ PhD, Christie PE MD, Nasser SM MRCP, Schmitz-Schumann M, Lee TH MD, London, United Kingdom; Wolfgang-Davos, Switzerland

543 Effect of Prednisone on Serodiagnosis of ABPA in Patients with CF Greenberger PA MD, Roberts M RN, Chicago, IL

544 Ambiguity in Diagnosing Allergic Bronchopulmonary Aspergillosis Rihal PS MD, Jerome D MD, Novey H MD, Long Beach, Irvine, CA

545 Cough Count (CC) as an Objective Outcome Parameter for Controlled Clinical Trials (CCT) of Asthma Therapy Henry J BS, Seroky J MA, Doyle W PhD, Skoner D MD, Pittsburgh, PA

546 Auto-Immune Syndromes Masquerading as Allergic Disease: Implications for the Practicing Allergist Guha B, Beals D, Smith JK, Krishnaswamy G, Johnson City, TN

547 Spontaneous Pneumothorax and Asthma in a Patient with Intermediate Alpha-1-Antitrypsin Deficiency Rosenfeld SI MD, Smith PH MD, Schwartz RH MD, Rochester, NY

548 Subglottic Schwannoma in a Child Holzhauer RJ MD, Pulver DW MD, Schwartz RH MD, Coniglio JU MD, Pulli R MD, Rochester, NY

549 Dysautonomia, Sports and Asthma Cap,~o-Filipe LM MD, Cap~o-Filipe JA MD, Delgado L MD, Rodrigues J MD, Cunha L MD, Barros H PhD, Castro-Correia J PhD, Vaz-Azevedo M MD, Porto, Portugal

LATEX ALLERGY

550 Association Between Sensitization to Natural Rubber Latex (NRL) and Papain Vandenplas O MD, Vandezande LM MD, Delwiche JP MSc, Jamart J MD, Looze Y PhD, Yvoir, Brussels, Belgium

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551 Assessment by Hycor RAST and Pharmacia CAP of Cross Sensitization to Banana and Avocado Among Latex Sensitive Hospital Employees Anderson G PhD, Li T PhD, Malki J PhD, Patel A PhD, Alem M PhD, Babakhin AA MD PhD, Cieslewicz G MD PhD, Zakirova I MD, Nolte H MD PhD, Pearson K MD, Sheffer AL MD, Du Buske LM MD, Boyce J MD, Boston, MA

552 Evaluation of the Clinical Significance of Serological Cross-Reactivity Between Latex and Ragweed Allergens Rao SG MD, McCullough JA BA, Bishop D RN, Ownby DR MD, Detroit, MI

553 Identification and Characterization of Avocado Chitinase with Cross-Reactivity to Latex Protein Akasawa A MD PhD, Hsieh L PhD, Tanaka K MS, Lin Y PhD, Iikura Y MD PhD, Tokyo, Japan; Bethesda, MD

554 Cross-Reactivity Between Wheat Germ Agglutinin (WGA) and Prohevein, a Major Latex Allergen Alenius H MSc, Kalkkinen N PhD, Turjanmaa K MD, Lauerma A MD, Reunala T MD, Palosuo T MD, Helsinki, Tampere, Finland

555 Immediate Type Hypersensitivity to Condurango Bark (CB) in a Patient Allergic to Natural Rubber Latex (NRL) Pfiitzner W, Thomas P, Przybilla B, Munich, Germany

556 Natural Rubber Latex (NRL) Allergy in Food Allergic Children Ylitalo L MD, Turjanmaa K MD, Reunala T MD, Tampere, Helsinki, Finland

557 Cross-Reactivity Between Latex and a Medicinal Plant: Marsdenia conduirango Justicia JL MD, Munoz MA MD, Segurado E MD, Barcelo M MD, Garcia JJ MD, Blanca M MD, Malaga, Spain

558 Latex Allergy in Operating Room Nurses Mace S, Sussman G, Stark DF, Thompson R, Kelly K, Beezhold D, Toronto, Ontario, Canada

559 Changes in Pulmonary Function After Skin Prick Testing with Latex Protein Extracts Magera B MD, Kelly KJ MD, Fink JN MD, Sullivan T MD, Gehring LL MS RNCS, Thompson R, Havens P MD, Kurup V PhD, Milwaukee, WI; Atlanta, GA

560 Comparison of Pharmacia CAP and Whole Blood Leukocyte Histamine Release in the Detection of Sensitivity to Latex Du Buske LM MD, Babakhin AA MD PhD, Cieslewicz G MD PhD, Nolte H MD PhD, Skov P Ph D, Zakirova I MD, Pearson K MD, Sheffer AL MD, Boyce J MD, Boston, MA

561 Latex Allergy in Office Practice Golden DBK MD, Matz J MD, Baltimore, MD

562 Latex Allergy Diagnosis: Standardization of a Natural Rubber Latex (NRL) Extract Sicard H MD, Turjanmaa K MD, Palosuo T MD, Alenius H MSc, Leynadier F MD, Autegarden JE MD, Andre C MD, Hrabina M MSc, Tran TX PhD, Fresnes, Paris, France; Tampere, Helsinki, Finland

563 Latex Skin and Serologic Testing in Operating Room Nurses Kelly KJ MD, Magera B MD, Kurup VP PhD, Fink JN MD, Sullivan T MD, Gehring LL MS RNCS, Xia JQ MD, Havens P MD, Thompson R, Milwaukee, WI; Atlanta, GA

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564 Latex Allergy: Comparison of IgE Immune Responses to Latex Proteins in Latex-Allergic Patients from 7 Hospitals in Europe, US and Canada Reunala T MD, Turjanmaa K MD, Kurup V MD, Yunginger JW MD, Storrs F MD, Sussman GL MD, Gold M MD, Fuchs T MD, Vervloet D MD, Palosuo T MD, Finland; WI; MI; OR; Canada; Germany; France

565 IgE Antibodies to 3 Purified Latex Proteins Measured by ELISA Palosuo T MD, Alenius H MSc, Kalkkinen N PhD, Turjanmaa K MD, Makinen-Kiljunen S MSc, Reunalta MD, Helsinki, Tampere, Finland

566 Prevalence of Latex Sensitivity Among Health Care Workers in an Allergy Clinic Eades JR MD, Murray JJ MD PhD, Nashville, TN

567 Latex Antibody in Asthmatics and Blood Donors and Latex Allergens in Paved Road Dust and Airborne Particles in Los Angeles LeBerthon B MD, Glovsky MM MD, Miguel A PhD, Weiss J PhD, Cass G PhD, Los Angeles, CA

568 A Questionnaire Survey of Latex Allergy in the Staff of an Australian Dental School Katelaris CH, Widmer RP, Lazarus R, Westmead, Sydney, Australia

569 Reduction in Airborne Latex Protein Exposure by Use of Low Protein, Powder-Free Gloves Siu SR MD, Smith GJ, Sussman GL MD, Swanson MC PhD, Yunginger J MD, Cividino MP MD, Brown SA RN, Beezhold D PhD, London, Ontario, Canada

570 In Vivo and In Vitro Evaluation of Allergenicity of Natural Rubber Latex (NRL) Gloves Used in Health Care: A Nationwide Study Turjanmaa K MD, Mfikinen-Kiljunen S MSc, Alenius H MSc, Reunala T MD, Palosuo T MD, Tampere, Helsinki, Finland

571 Characterization of Latex Allergens by Capillary Electrophoresis Chen HD MS, Chen CL PhD, Huang SW MD, Gainesville, FL

572 Electrophoretic Characterization of Latex Allergens by Two-Dimensional Electrophoresis Posch A PhD, Chen Z PhD, Raulf-Heimsoth M PhD, Baur X MD, Bochum, Germany

573 Latex Allergen Levels In Disposable Medical Gloves Sussman GL MD, Pugh B, Beezhold DH PhD, Toronto, Ont., Canada; Dothan, AL; Sayre, PA

574 A Multicenter, Longitudinal Study of Natural Rubber Latex (NRL) Allergy in Nursing Students (NS) Steinberg P MD, Pheley AM PhD, O'Hara CM RN, Minneapolis, MN

575 The Relationship Between Latex Allergies, Hydration and Compromised Barriers in Surgical Gloves Thompson R BS, Korniewicz D DNSc RN, Bennett J PhD, Kelly K MD, Murali PS PhD, Kurup V PhD, Fink J MD, Hartland, Milwaukee, WI; Washington DC; Houston, TX

576 HLA Immunogenetics and the Specific IgE Response to Hevea Latex Antigens Rihs HP PhD, Chen Z PhD, Cremer R MD, Allmers H MD, Baur X MD, Bochum, Cologne, Germany

577 Intravenous Catheter Hypersensitivity Alvarado A MD, Abramson SL MD PhD, Rosenblatt HM MD, Kline MW MD, Shearer WT MD PhD, Houston, TX

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Latex Hypersensitivity in Emergency Medical Service Providers Safadi GS MBBS, Corey EC MD, Taylor JS MD, Pien LC MD, Wagner WO MD, Melton AL MD, Cleveland, OH

Latex Sensitivity and Latex Allergy in Atopic and Non-Atopic Children Liebke C, Niggemann B, Wahn U, Berlin, Germany

Impact of a Restrictive Latex Glove Policy on Identification of Latex Allergic Health Care Workers at a Tertiary Care Hospital Cohn JL BA, McTier A MD, Pesaros P MD, Crook M BA, Woodard RR RN, Band JD MD, Lauter CB MD, Royal Oak, MI

Specific IgE Response in Mice Immunized with a Recombinant Latex Protein Cahaly RJ MD, Granady LC MD, Slater JE MD, Washington, DC

FOOD ALLERGY

582 Identification of Unique Antigenic Fractions of Soy and Peanut Eigenmann PA MD, Burks AW MD, Bannon GA PhD, Sampson HA MD, Baltimore, MD; Little Rock, AR

583 Antihistamine Prophylaxis for Low Grade Exposure in Severe Peanut Anaphylaxis Spiegel WA MD, Anolik R MD, Posner MA MD, Philadelphia, PA

584 PBMC Proliferative and Cytokine Responses to Peanut Hourihane JO'B MRCPI, Clarke MCA Bsc, Warner JO MD, Dean TP PhD, Southampton, United Kingdom

585 Peanut Anaphylaxis: An Allergist-Immunologist's Personal Experience with Food Cross-Contamination Kemp SF MD, Lockey RF MD, Tampa, FL

586 A Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) for the Quantitation of Peanut in Foods Taylor SL PhD, Nordlee JA MS, Hefle SL PhD, Lincoln, NE

587 Amino Acid Sequence Analysis and Cloning of the Major Peanut Allergen, Ara h II Stanley JS PhD, Burks AW MD, Cockrell G, Helm RM PhD, Bannon GA PhD, Little Rock, AR

588 IgE-Binding Epitopes on Ara h I, a Legume Vicilin Protein and a Major Peanut Allergen Burks AW MD, Stanley JS PhD, Cockrell G, Blake T, Helm RM PhD, Bannon GA PhD, Little Rock, AR

589 Characterization of the Major Peanut Allergen Ara h 1 on Protein Level Becker W-M PhD, Buschmann L PhD, Schlaak M MD, Borstel, Germany

590 Peanut Allergen Ara h I: Identifying the Clinically Relevant Epitopes Bannon GA PhD, Stanley JS PhD, Cockrell G, Helm RM PhD, Sampson HA MD, Burks AW MD, Little Rock, AR; Baltimore, MD

591 Two-Dimensional SDS-Polyacrylamide (SDS-PAGE) Gel Analysis of a 14kD Peanut Allergen Vanness E BS, Paradeis B BS, Hefle S PhD, Bush RK MD, Madison, WI

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592 Anaphylaxis to Casein in an Adult Patient Guinnepain MT MD, Bernard H PhD, Bloch-Morot E MD, Laurent J MD, David B MD, Peltre G PhD, Wal JM PhD, Paris, Saclay, France

593 Evaluation of Cow's Milk Formula AUergenicity and Tolerogenicity by Intestinal Mast Cell Protease Release in the Rat Model Fritsch6 R, Schwarz C, Martin C, Lausanne, Switzerland

594 Release of Inflammatory Mediators After Cow's Milk Intake in a Newborn with Idiopathic Pulmonary Hemosiderosis (IPH) Torres MJ MD, Blanca M MD, Gir6n M MD, Corzo JL MD, Rodriguez F MD, Moreno F PhD, Perez E MD, Martinez-Valverde A MD, Malaga, Spain

595 Allergenic Properties of Ovomucoid, the Dominant Egg Protein Cooke SK SB, Rowe JJ BA, Eigenmann PA MD, Huang SK PhD, Sampson HA MD, Baltimore, MD

596 Wheat Alpha Amylase Inhibitor, a 15 Kd Protein, is an Allergen in Wheat-Allergic Patients Sixbey JP BS, James JM MD, Helm RM PhD, Bannon GA PhD, Burks AW MD, Little Rock, AR

597 An Indirect Enzyme-Linked Immunosorbent Assay (ELISA) for the Quantitation of Whey in Foods Hefle SL PhD, Shimakura K PhD, Taylor SL PhD, Lincoln, NE

598 Breast Milk Fatty Acid Composition Following Maternal Exclusion Diet Hunt AN PhD, Pollard C MPhil, Hourihane JO'B MRCPI, Bevin S MRCP, Little SA PhD, Warner JO MD, Dean TP PhD, Southampton, United Kingdom

599 IgE Response to Bovine Colostral IgG and to Their F(ab)'2 Fragments in Milk Allergic Patients Vercaigne-Marko D PhD, Wal JM PhD, Lefranc-Millot C PhD, Lepretre A PhD, Peltre G PhD, Dhulster P PhD, Guillochon D PhD, Villeneuve d'.4sq, Saclay, Paris, France

600 Effect of Bioactive Plant Compounds on the Small Intestine Transmucosal Passage of Milk Allergens in Normal and Sensitized Rat Wal JM PhD, Gee J PhD, Atkinson H PhD, Grigoriadou F PhD, Wortley GM PhD, Wijnands MV PhD, Penninks AH PhD, Miller K PhD, Johnson IT PhD, Saclay, France; Norwich, Carshalton, United Kingdom; Zeist, The Netherlands

601 TNF~ Secretion in Cow's Milk Allergy with Intestinal or Skin Symptoms Heyman M, Benlounes N, Desjeux JF, Candalh C, Blaton MA, Darmon N, Dupont C, Paris, France

602 Effect of Lactoferrin on GM-CSF Release from Human Nasal Polyp Cells Vergnes C, Lebel B PhD, Bousquet J MD, Campbell AM PhD, Montpellier, France

603 Cross-Reactivity of Pen a 1, the Major Shrimp Allergen and Mouse Tropomyosin? Reese G PhD, Jeoung B-J MD, Daul CB MD PhD, Lehrer SB PhD, New Orleans, LA

604 A Monoclonal Antibody-Based Sandwich ELISA to Quantify the Major Shrimp Allergen Pen a 1 Jeoung B-J MD, Reese G PhD, Daul CB MD PhD, Lehrer SB PhD, New Orleans, LA

605 Monospecific Allergy to Swordfish Kelso JM MD, Jones RT BS, Yunginger JW MD, San Diego, CA; Rochester, MN

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606 Asthma After Consumption of Snails in Housedust Mite Allergic Patients: A Case of IgE Crossreactivity van Ree R, Akkerdaas JH, Pajno GB, Corbetta L, Ferro G, Zambito M, Garritani MS, Bonifazi F, Aalberse RC, Antonicelli L, Amsterdam, The Netherlands; Ancona, Messina, Palermo, Venezia, Italy

607 Eggplant Anaphylaxis: Isolation of the Major Allergens and Demonstration of Cross-Reactivity with Other Solanaceae Muthiah R PhD, Zondlo A, Zondlo J MD, Kagen SL MD, Appleton, WI

608 Peach Allergy With No Pollen Sensitization In Children Morais de Almeida M, Santa Marta C, Prates S, Abreu Nogueira JM, Rosado Pinto JE, Lisbon, Portugal

609 Study of Allergenicity of Peel and Pulp from Rosaceae Fruits FeruCmdez Rivas M MD PhD, Martinez A PhD, Cuevas M MD PhD, Avila, Bilbao, Madrid, Spain

610 IgE Antibodies Cross-Reaction Between Der p 1, the Major Allergen of Dermatophagoides Pteronyssinus and Ananain, a Cysteine Proteinase from Ananas Comosus, the Pineapple Plant Musu T BS, Rabillon J, David B MD, Dandeu JP PhD, Guinnepain MT MD, Looze Y PhD, Paris, France

611 Immunological Cross-Reactivity of Apple 18 kD Allergen and Constituents of Common Vegetables Hsieh L-S PhD, Martin B PhD, Hadswiger L PhD, Bethesda, MD; Pullman, WA

612 Allergy to Chicory (Witloof) Helbling A MD, Reimers A MD, W~ilti M PhD, Borgts R MD, Bern, Switzerland

613 Wine Histamine Content Does Not Influence the Tolerance of Wine in Normal Subjects Kanny G MD, Bauza Th PhD, Fremont S MD, Dauca M PhD, Grignon G MD, Cabanis JC PhD, Nicolas JP MD, Moneret-Vautrin DA MD, Nancy, France

614 Food Allergy in Human Immunodeficiency Virus (HIV) Infection Tubiolo VT MD, Vazzo LA RD, Beall GN MD, Torrance, CA

615 Is Multiple Food Protein Intolerance (MFPI) the Cause of "Reflux Oesophagitis" in Distressed Infants Hill DJ FRACP, Catto-Smith ACS MD FRACP MRCP, Cameron DJS FRACP, Chow CW FRCPA, Francis DM APD, Hosking CS MD FRACP FRCPA, Melbourne, Australia

616 Diagnostic Value of ALCAT Test in Intolerance to Food Additives Compared with Double-Blind Placebo-Controlled (DBPC) Oral Challenges Hoj L MD, Copenhagen, Denmark

617 The Incidence and Principal Foods of Food Allergy in Korean Children with Asthma Kim K-E MD, Jeoung B-J MD, Lee K-Y MD, Seoul, Korea

618 The Effects of Oral Disodium Cromoglycate (DSCG) on the Basic Types of Nasal Response (NR) to Food Ingestion Challenge (FICH) and Accompanying Cellular Changes in Nasal Secretions (NS) Knottnerus I MD, Pelikan DMV MD, Pelikan Z MD, Breda, The Netherlands

619 Screening of Soybean Germplasm for Binding to IgE by Immunoelectroblotting Nordlee JA MS, Taylor SL PhD, Lincoln, NE

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INSECT ALLERGY

620 Immunoblot Analysis of Salivary Gland Antigens in 10 Mosquito Species Li H RT, Simons FER MD, Peng Z MD, Winnipeg, Canada

621 IgE and IgG4 Saliva-Specific Antibodies in Mosquito Hypersensitive Patients from Finland, Canada and USA Palosuo K, Peng Z, Simons FER, Engler RJM, Reunala T, Brummer-Korvenkontio H, Helsinki, Finland; Winnipeg, Canada; Washington, USA

622 Routine Testing of Mosquito Bite Allergic Patients Greinecker G, Hemmer W, Focke M, G0tz M, Jarisch R, Vienna, Austria

623 Anaphylactic Shock to Tick (Ixodes Ricinus) Moneret-Vautrin DA MD, Beaudouin E MD, Kanny G MD, Roche JF MD, Gu6rin L PhD, Nancy, France

624 Rush Venom Immunotherapy in Patient with Previous Anaphylaxis During Venom Immunotherapy Fischer DA MD, Payton KB MD, Butchey JRK MD, London, ON, Canada

625 Prevalence of Systemic Adverse Reactions to Hymenoptera Sting in a General Population in Uruguay Baluga JC, Fierro W, Schuhl JF, Montevideo, Uruguay

626 Compartment Syndrome: An Unusual Manifestation of Hymenoptera Hypersensitivity Peralta FG MD, Richerson HB MD, Iowa City, 1.4

627 Neutralization of Africanized Bee Venom by Antitoxic Antibodies Schumacher MJ MB, Egen NB PhD, Tanner D, Tucson, AZ

628 Development of a Specific Instrument to Measure Health Related Quality of Life (HRQL) in Hymenoptera Allergic Patients Oude Elberink JNG, Dubois AEJ, Guyatt GH, de Monchy JGR, Groningen, The Netherlands; Hamilton, Canada

629 Cross Reactivity Between Bee and Snake Venoms Rodriguez RJ MD, Hershey J BS, Smith LJ MD, Vick J PhD, Hamilton RG PhD, Engler RJM MD, Washington, DC

630 Fire Ant Induced Skin Tissue Loss and Infection in a Nine Month Old Child Lockey RF MD, Hernandez LS MD, Swank RL MD, Coughlin JP MD, Tampa, FL

631 Enzymatic, Antigenic and Physico-Chemical Properties of Recombinant Hyaluronidase Soldatova LN PhD, Crameri R PHD, Kreil G PhD, Kemeny DM PhD, Mtlller UR MD, Bern, Switzerland

632 Skin Tests (ST) and Histamine-Release (HR) Assays Using Histamine-Free Venom Extracts: a One-Year Follow-Up in Ten Patients with Wasp Venom Immunotherapy Vuitton DA, Didier JM, Adessi B, Gibey R, Laurent R, Kantelip JP, Besancon, France

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ADVERSE DRUG REACTIONS

633 Adverse Reaction to Porcine Heparin Bommanna VM MD, Polasani R MD, Ballow M MD, Buffalo, NY

634 Increased Prevalence of Angiotension-Converting Enzyme Inhibitor (ACE-I) Drug Induced Angioedema in Cardiac Transplant and Renal Transplant Patients (pts) Anderson JA MD, Abbosh JM MD, Levine AB MD, Kupin WL MD, Detroit, MI

635 Continued Treatment With Flourouracil for Colon Cancer Despite Severe Phototoxic Dermatitis Moyer DB MD, Oakland, CA

636 Creatine Phosphokinase Elevation Secondary to Metered Dose Inhaler Albuterol Therapy Craig TJ DO, Singh RF PharmD, Baker WH MD, Iowa City, IA

637 Atrial Fibrillation Induced by an Interaction of Salmeterol (S), Albuterol & Clarithromycin(C) Young RM MD, Kosuri S MD, Silbert D MD, Jonas E MD, East Meadow, NY

638 Antihistamines and Risk of Cardiac Events Verspeelt J MD, Amery W MD PhD, Jones J MD PhD, Staffa J MS RPH, Gable CB PhD MA, Beerse, Belgium," Arlington, VA

639 Effect of Non-Sedating vs. Sedating Antihistamine Therapy in the Elderly McNeil DL MD, Detillio P LPN, Aslanian W MD, Columbus, OH

640 A Randomized, Placebo-Controlled Study to Evaluate the Electrocardiographic Effects of Cetirizine in Children Aged 6 to 11 Winder J MD, Noonan MJ MD, Sylvania, OH; Bend, OR

641 Astemizole is Not Carcinogenic in Mice and Rats Benze J PhD, Gypen L LicPhysics, Lampo A DVM, Vandenberghe J DVM, De Coster R DVM PhD, Bowden C PHD, Van Cauteren H DVM, Beerse, Belgium

642 Necrotizing Cutaneous Lesions as a Complication of Subcutaneous Interferon Beta-lb Benincasa P MD, Bielory L MD, Newark, NJ

643 Food Additives as a Cause for Bullous Drug Eruption Traenckner I, Langrock A, Weyers W, Schill WB, Giessen, Germany

644 Vancomycin-Induced Stevens-Johnson Syndrome Alexander II MD, Greenberger PA MD, Chicago, IL

ALLERGIC DRUG REACTIONS

645 Allergic Reactions During General Anesthesia (GA) Knowles SR BScPhm, Weber E MD, Shear NH MD, Toronto, Canada

646 Anaphylaxis to Mivacurium in a 65 Year Old Female Hatch RT MD, Holman TR MD, Longview, TX

647 The Diagnosis of Anaphylactic Reactions to Muscle Relaxants by Flow Cytometry Leynadier F MD, Rajoely B MD, Ghazouani E MD, Firat H, Pecquet C MD, Abuaf N MD, Paris, France

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648 Histamine and Sulfidoleukotriene SL Release from Peripheral Blood Leukocytes (PBL) of Patients with Anaphylactoid Reactions Provoked by Acetylsalicylic Acid (ASA) Brunner B MS, Eberlein-Konig B MD, Przybilla B MD, Munich, Germany

649 Challenge with Nimesulide, a New NSAID, In Patients with Reactions to Aspirin and Other NSAIDS Bernstein M MD, Rodriguez C MD, Caracas, Venezuela

650 Copolymer-1 (Copaxone®) Induces a Non-Immunologic Activation of Connective Tissue Type Mast Cells Shalit M MD, Meiner Z MD, Levi-Schaffer F PhD, Jerusalem, Israel

651 Interferon beta-lb (IF 13) Hypersensitivity and Desensitization Young MC MD, Otis J MD, South Weymouth, MA

652 Acute IgE-Mediated Generalized Urticaria-Angioedema After Topical Application of Povidone-Iodine L6pez Sfiez MP MD, Prieto A MD, Olalde S MD, Armentia L PharmD, Baeza ML MD, Montoro A MD, Barrio de M MD, Madrid, Spain

653 Allergic Reactions to Methylprednisolone Hemisuccinate: One Case Murrieta-Agutes M MD, Duarte-Risselin C MD, Leynadier F, Paris, France

654 Positive Intracutaneous and Oral Provocation Test in a Child with an Anaphylactoid Reaction to Paracetamol Vieluf D MD, Vieluf I, Brockow K MD, Abeck D MD, Hamburg, Munich, Germany

655 Murine Model of Sulfamethoxazole-Protein Substitution Pesenko RD, Do T, Gruchalla RS MD PhD, Dallas, TX

656 Sulfamethoxazole-Specific Antibodies in Patients with AIDS: A Prospective Study Coeshott C PhD, Cook C, Ohnemus C, Burman W MD, Caraway P RN, Cohn D MD, McCall C DPhil, Denver, CO

657 Oral Desensitization to Trimethoprim Sulfamethoxazole in Patients with HIV Lee-Wong MF MD, Resnick D MD, Waldron M MD, New York, NY

658 Antibiotic Allergy in HIV-Infected Children Schuval S J, Bonagura VR, New Hyde Park, NY

659 Can Oral Penicillin Challenge Replace Minor Determinant Skin Testing? DeMasi JM MD, Albany, NY

660 The Effect of Penicillin Skin Testing on Antibiotic Usage in a Large HMO Macy EM MD, Kaiser Permanente Allergy Department, San Diego, CA

661 Immediate Allergic Reactions to Penicillins: Relationship Between Drug Use Pattern and Reaction Specificity Romano A MD, Blanca M MD, Quarantino D MD, Mayorga C PhD, Di Fonso M MD, Venuti A MD, Rome, Italy; Malaga, Spain

662 Recurrent Pustular Eruption Induced by Amoxycillin Prieto A MD, Lopez-Saez P MD, Olalde S MD, Montoro A MD, Lecona M MD, Zazo V MD, de Barrio M MD, Madrid, Spain

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Selective Immediate Allergic Response to Penicillin V Carmona MJ MD, Blanca M MD, Moreno F BS, Garcia J MD, Vega JM MD, Segurado E MD, Justicia J MD, Malaga, Spain

IgE Antibodies to the Benzylpenicilloyl (BPO): Comparison of a RAST Assay with Three Different Carriers Blanca M MD, Moreno F BS, Garcia J MD, Vega JM MD, Fernandez J MD, Terrados S MD, Miranda A MD, Carmona MJ MD, Malaga, Granada, Elche, Spain

Cefazolin Specific Side Chain Hypersensitivity Weber EA BSc MD FRCP(C), Toronto, Ontario, Canada

ANAPHYLAXIS

666 Anaphylaxis in Olmsted County Yocum MW MD, Silverstein MD MD, Klein JS MD, Rochester, MN

667 Idiopathic Anaphylaxis: Long Term Follow-Up, Cost and Outlook Krasnick J MD, Patterson R MD, Harris KE BS, Chicago, IL

668 Human Seminal Plasma (HSP) Anaphylaxis Ebo DG MD, Stevens WJ MD, Bridts CH MT, De Clerck LS MD, Antwerpen, Belgium

669 Anaphylactic Response to Thiamine (Vitamin B-I) Fernandez M PhD, Blanca M MD, Torrecillas M MD, Mufios C MD, Garcia J MD, Malaga, Spain

670 Anaphylaxis and Flushing After the Administration of Intranasal Fluticasone Propionate Melamed J MD, Stone B MD, Beaucher W MD, Chelmsford, MA

671 Exercise-Induced Anaphylaxis Associated with Apple Juice Ingestion Hickey RW MD, Ballow M MD, Buffalo, NY

672 Risk Factors (RF) of Systemic Reactions (SR) to Immunotherapy (IT) Nguyen MT MD, Oakland, CA

673 A Case Study of an Allpyral Prolonged Anaphylactic Reaction Livingston AE MD, Ford JA BSN, Hamlin GB Jr MS, Syracuse, NY

674 Anaphylaxis in the Allergy Office Golden D MD, Schartz HJ MD, Anaphylaxis Committee, Baltimore, MD

675 IgE Mediated Uricaria to Tetanus Toxoid Antigen Mufioz MA MD, Segurado E MD, Justicia JL MD, Mayorga C PhD, Carmona MJ MD, Garcia J MD, Blanca M MD, Malaga, Spain

676 Latent Period of Tryptase Serum Peak Levels in Allergic Drug Reactions Ordoqui E MD, Aranz~ibal A MD, Zubeldia JM PhD, de Barrio M MD, L6pez-S~iez MP MD, Prieto A MD, Rodriguez VM MD, Baeza ML MD, Madrid, Spain

677 Community-Based Education of Anaphylaxis Dubravec MS MD, Battafarano N MD, Spaulding H MD, Aurora, CO

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POSTER SYMPOSIUM MONDAY, MARCH 18, 1996

2:00 PM TO 5:00 PM

NEW INSIGHTS INTO AIRWAY INFLAMMATION: MECHANISM AND MANAGEMENT Moderators: William Busse, M.D. and Stanley Szefler, M.D.

678 Effect of 6h Exposure to 50ppb Ozone (03) on release of IL-8 and RANTES from Nasal Epithelial Cells (NEC) From Atopic Rhinitics and the Influence of Fluticasone Propionate (FP), In Vitro Calder6n MA MD, Devalia JL PhD, Prior AJ MBChB, Davies RJ FRCP, London, United Kingdom

679 Increased Levels of IL-13 and MCP-1 in Nasal Secretions Following Allergen Challenge Reece LM BS, Alam R MD PhD, Sim TC MD, Galveston, TX

680 Comparison of Environmental Challenge to Cat with Bronchial and Nasal Allergen Challenge Sicherer SH MD, Wood RA MD, Eggleston PA MD, Baltimore, MD

681 The Influence of Loratadine (LO) on Bronchial Histamine Challenge, Early (EAR) and Late (LAR) Asthmatic Reactions and the Development of Bronchial Reactivity after Single Allergen Challenge Cieslewicz G MD PhD, Grzelewska-Rzymowska I MD PhD, Du Buske LM MD, Gondorowicz K MD PhD, Wojciechowska B MSc, Rozniecki J MD PhD, Krol M MSc, Juszczyk G MD, Lodz, Zabrze, Poland; Boston, MA

682 Effect of ICAM-1 Blockade on Inflammation and Airway Dysfunction During Acute Sendai Virus Illness in Rats Sorkness R PhD, Mehta H MD, Kaplan M BS, Hefle S PhD, Haase S, Miyasaka M MD PhD, Lemanske RF Jr MD, Madison, WI

683 Detection of Rhinovirus 16 (RV16) RNA in the Lower Airway of Experimentally-Infected Subjects Gem JE MD, Galagan DM BS, Jarjour NN MD, Kelly EAB PhD, Busse WW MD, Madison, WI

684 Rhinovirus Infection Increases ICAM-1 Expression in Pulmonary Epithelium Papi A, Johnston SL, Southampton, United Kingdom

685 Effect of Inhaled Mometasone Furoate on Inflammatory Cell Influx and Cytokine Levels in the Lungs of Allergic Mice Chapman RW PhD, Sehring SA BS, Garlisi CG PhD, Falcone A BS, Kung TT PhD, Stelts D BS, Minnicozzi M PhD, Jones H, Umland SP PhD, Kreutner W PhD, Kenilworth, NJ

686 Serum Osteocalcin (SO) and Procollagen (PICP) as Markers for Osteoporotic Fracture Risk in Steroid Dependent Asthmatics Toogood JH MD, Fraher LJ PhD, Cheng S, Baskerville J PhD, Ontario, London, Canada

687 Misoprostol, a PGE1 Analog, Improves the Physiologic and Inflammatory Changes of Nocturnal Asthma Feldsien DC BA, Sloan SI BS, Wenzel SE MD, Denver, CO

688 Intravenous Immune Globulin (IVIG) Enhances Glucocorticoid (GC) Sensitivity Spahn JD MD, Szefler SJ MD, Nimmagadda SR MD, Gelfand EW MD, Leung DYM MD PhD, Denver, CO

689 Pathological Markers of Airway Inflammation in Childhood Asthma Resnick IB MD, Shcherbina AJ MD, Kovalev GI MD, Kulak JV MD, Naszimov V MD, Mysin A MD, Prodeus AP MD, Bologov AA MD, Moscow, Russia

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691

692

693

694

695

696

697

Immunocytochemical Study of Inflammation in Airways of Surgically Resected Lungs from Asthmatic and Non-Asthmatic Subjects Hamid QA, Ying Lee S, Minshall E, Elliott M, Hogg JC, Montreal, Vancouver, Canada

Comparison of Two Methods of Obtaining Induced Sputum (IS) Samples in Asthmatic Subjects Gershman N, Liu J, Wong H, Mahlmeister M, Fahy J, San Francisco, CA

The Safety of Asthma and Allergy Medications During Pregnancy Schatz M MD, Zeiger R MD PhD, Harden K RN, Hoffman C MD, Petitti D MD, San Diego, CA

Variability in Asthma Claims by Geographic Regions Stempel DA MD, Carlson AM PhD, Buchner DA PhD, Seattle, WA; Bloomington, MN; Kenilworth, NJ

Cord Blood IgE Concentrations Predict Methacholine and Skin Test Responses in Six Year Old Children Ownby DR MD, Johnson CC PhD, Peterson EL PhD, Detroit, MI

Refining Factors Which Predict the Complex Trait Asthma Freidhoff L MS, Barnes K PhD, Maestri N PhD, Ferbert-Harris P PhD, Togias A MD, Rosenthal R MD, Malveaux F MD, Marsh D PhD, Baltimore, MD; Washington, DC

Predictive Value of Skin Tests and RASTs in Diagnosis of Cat Allergy Wood RA MD, Flanagan E, Eggleston PD, Baltimore, MD

Fluticasone Propionate 50MCG Bid and 100MCG Bid Improves Functional Status and Decreases Sleep Disturbances in Children with Asthma Mahajan P, Okamoto L, Bosh T, Kellerman D, Baker K, Bronsky E, Research Triangle Park, NC; London, United Kingdom; Salt Lake City, UT

ORAL SESSION MONDAY, MARCH 18, 1996

3:00 PM TO 5:00 PM

EOSINOPHILS, BASOPHILS, AND MAST CELLS Moderators: J. Andrew Grant, M.D. and Martin Church, M.D.

698 3:00 pm The Crystal Structure of Human Charcot-Leyden Crystal Protein, Eosinophil Lysophospholipase, Identifies it as a New Member of the Carbohydrate Binding Family of Animal Galectins Ackerman SJ PhD, Leonidas DD PhD, Elbert BL MS, Zhou Z-Q PhD, Leffler H PhD, Acharya KR PhD, Boston, MA; Bath, England

699 3:12 pm Apoptosis of Neutrophils (Neu) and Eosinophils (Eos) and Their Ingestion by Macrophages is Associated with the Resolution of Allergen-Induced Cutaneous Late Phase Response (LPR) Kay AB, Meng Q, Taborda-Barata L, Ying S, London, United Kingdom

700 3:24 pm Eosinophils Express and Produce IL-4, IL-8, and IL-10-Evidence for Stored and Newly Synthesized Cytokine Nakajima H MD, Gleich GJ MD, Kita H MD, Tochigi, Japan; Rochester, MN

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701 3:36 pm Expression of High Affinity IgE Receptors (FceRI) on Peripheral Blood Basophils, Monocytes and Eosinophils in Atopic Subjects Kon OM MD, Sihra BS MD, Grant JA MD, Kay AB MD, Galveston, TX," London, United Kingdom

702 3:48 pm The Effect of Treatment with a Monoclonal Antibody Directed Against IgE on Allergic Airway Responses in Asthmatic Subjects Fahy JV MB, Fleming HE MD, Wong HH BS, Liu JT MS, Su JQ PhD, Reinmann J PhD, Fick Jr. RB MD, Boushey HA MD, San Francisco, CA

703 4:00 pm Human Recombinant IgE-Dependent Histamine Releasing Factor (HrHRF) Enhances IL-4 Secretion by Human Basophils Schroeder JT PhD, Lichtenstein LM MD PhD, Kagey-Sobotka A PhD, MacDonald SM MD, Baltimore, MD

704 4:12 pm Interleukin-13 Production by Human Basophils Sim TC MD, Li H MD, Reece LM BS, Alam R MD PhD, Galveston, TX

705 4:24 pm Cytokine Production by Highly-Purified Human Cultured Basophils Tachimoto H MD, Ebisawa M MD, Kimata M BS, Fukagawa K MD, Matsumoto K MD, Saito H MD, Yangihara Y PhD, Iikura Y MD, Tokyo, Japan

706 4:36 pm Cultured Human Mast Cells are Capable of Producing Multiple Cytokines and Chemokines Ebisawa M MD, Tachimoto H MD, Saito H MD, Iikura Y MD, Tokyo, Japan

707 4:48 pm Activated Human Lung Fragments and Human Mast Cells Synthesize IL-13 Jaffe JS MD, Wang Y MS, Post TJ MS, Glaum MC MS, Raible DG MD, Mohanty JG PhD, Butterfield JH MD, Lang DM MD, Schulman ES MD, Philadelphia, PA

CYTOKINE MODULATION OF THE ALLERGIC RESPONSE Moderators: Donald Leung, M.D. and David Huston, M.D.

708 3:00 pm IL-5 Secretion by Allergen-Specific CD4+ Cells in Shortterm Culture: Dissociation from Allergen-Induced Proliferation and Dependence on B7-2 Co-Stimulation Bungre J, Till S J, Larch6 M, Humbert M, Robinson D, Huston D, Dickason R, Kay AB, Corrigan C, London, United Kingdom; Houston, TX

709 3:12 pm Creation of a Functional IL-5 Monomer Targets a Single Helical Bundle for the Development of Therapeutic Analogues Dickason RR BS, Huston DP MD, Houston, TX

710 3:24 pm IL-4-Induced Immunoglobulin Class Switching Involves Protein Tyrosine Phosphatase Activity Imani F PhD, Rager KJ MS, Marsh DG PhD, Baltimore, MD

711 3:36 pm Prostaglandin E 2 (PGE 2) Causes Inhibition of CD40 Ligand (CD40L) Expression on Activated Human T-Cells Which is Reversible with IL-2 or IL-4 Homer AA MD, Beck LG BA, Spiegelberg H MD, San Diego, CA

712 3:48 pm Transcriptional Regulation of the Human IL-4 Gene in Asthma lnamura H MD, Klemm D PhD, Dresback J BS, Rosenwasser LJ MD, Denver, CO

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494 Program J ALLERGY CLIN IMMUNOL JANUARY 1996

713 4:00 pm

714 4:12 pm

715 4:24 pm

716 4:36 pm

717 4:48 pm

Transcriptional Correlations of Cytokine Gene Promoter Polymorphisms in Asthma Dresback J BS, Klemm D PhD, Inamura H MD, Mascali J BS, Borish L MD, Rosenwasser LJ MD, Denver, CO

Contribution of Interleukin (IL)-10 Promoter Polymorphism to Allergic Inflammation Hobbs K MD, Mascali J, Klemm D PhD, Borish L MD, Denver, CO

NF-•B as a Mediator of Differential Gene Expression in T Helper Cell Subsets Casolaro V MD, Georas SN MD, Chiu JY BA, Song Z MD, Thanos D PhD, Lichtenstein LM MD PhD, Ono SJ PhD, Baltimore, MD; New York, NY

Alterations in Glucocorticoid (GC) Receptor (R) Binding to DNA Contributes to Steroid Resistant (SR) Asthma Klemm DJ PhD, Surs W BS, Spahn JD MD, Szefler SJ MD, Leung DYM MD PhD, Denver, CO

Inhibition of Specific IgE Antibody Formation by Naked Plasmid DNA Immunization Raz E MD, Tighe H PhD, Sato Y MD, Roman M PhD, Swain S PhD, Carson D MD, Spiegelberg H MD, La Jolla, CA

ANAPHYLAXIS Moderators: Gillian Shepherd, M.D., and Howard Schwartz, M.D.

718 3:00 pm Protamine Hypersensitivity Complicating Desensitization to Insulin Bollinger ME DO, Wood RA MD, Baltimore, MD

719 3:12 pm In Vitro Demonstration of IgE to Folate-Albumin in Anaphylaxis from Folate Dykewicz MS MD, Orfan NA MD, Sun W MD, St. Louis, MO; Cooperstown, NY

720 3:24 pm Vancomycin Anaphylaxis Associated with IgE and IgG Antibodies Goldman MH MD, Hamilton RG PhD, Stellato C MD, Kagey-Sobotka A PhD, Adkinson Jr NF MD, Baltimore, MD

721 3:36 pm Anaphylaxis After Ingestion of Wheat Flour Contaminated with Dust Mites Blanco C MD, Carrillo T PhD, Castillo R MD, Quiralte J MD, Delgado J PhD, Las Palmas de Gran Canaria, Canary Islands, Spain

722 3:48 pm Postmortem Diagnosis of an Anaphylactoid Reaction Due to Non-Ionic Radiocontrast Media by Serum Tryptase Analysis: A Case Report Brockow K MD, Vieluf D MD, Ring J MD PhD, Mi~nchen, Hamburg, Germany

723 4:00 pm tx- and 13-Tryptase Levels in Near-Miss Sudden Infant Death Syndrome (SIDS) Patients Hogan AD MD, Dolan MA MD, Abernathy CK MS, Irani AM MD, Schwartz LB MD PhD, Richmond, VA

724 4:12 pm Use of Nimesulide in Aspirin Sensitive Patients: A Long Term Evaluation Andri L MD, Senna GE MD, Andri G MD, Dama AR MD, Scaricabarozzi I PhD, Verona, Italy

725 4:24 pm Assessment of Human Seminal Plasma Hypersensitivity Prevalence in North America Using a Validated Questionnaire Bernstein JA MD, Sugumaran R, Bernstein DI MD, Bernstein IL MD, Cincinnati, OH

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726 4:36 pm IgE-Mediated Systemic Reactions to Gelatins Included in Vaccines Inouye S MD, Sakaguchi M PhD, Ogura H MD, Tokyo, Kochi, Japan

727 4:48 pm Correlation of Skin Bite Reactions and Serum Mosquito-Specific IgE Among Three Mosquito Species with Worldwide Distribution Peng Z MD, Yang J MD, Simons FER MD, Winnipeg, Canada

THEMATIC POSTER SESSION TUESDAY, MARCH 19, 1996

8:30 AM TO 11:30 AM

URTICARIA AND ANGIOEDEMA

728 Cutaneous Responses to VIP and SOM in Healthy Adults(HA), Delayed Pressure (DPU) and Chronic Idiopathic Urticaria (CIU): The Effect of Cetirizine and Dimethindene Borici-Mazi R MD, Kouridakis S MD, Kontou-Fili K MD, Athens, Greece

729 Hypodermic Epinephrine (EPI) Spray and Uvular Angioedema Revisited Bateman H MD, Peltz S MD, Reyes R MD, Oppenheimer J MD, Bielory L MD, Newark, NJ

730 Hydroxychloroquine (HCQ) in Corticosteroid-Dependent Chronic Urticaria (CDCU) Lammert JK MD PhD, Robinson DM MD, Seattle, WA

731 Predictive Relationship Between the Severity of Cold Urticaria and the Area of the Ice-Cube Test Mathelier-Fusade P MD, Abbas N MD, Chabane MH MD, Leynadier F MD, Paris, France

732 Autologous Serum Skin Testing of Patients with CIU Can Produce a Cutaneous Late Phase Response Joks R MD, McClain SA MD, Josephson AS MD, Brooklyn, NY; Stony Brook, NY

733 Angioedema--Unusual Causes Varner A MD, Kumar A MD, Bush R MD, Madison, WI

734 Urticarial-like Skin Eruption as a Prodrome to Attacks of Hereditary Angioedema (HAE) Ruddell DN MD, Stafford CT MD, Augusta, GA

735 Chronic Idiopathic Urticaria Associated With Hypogammaglobulinemia Lee KR MD, Warrington RJ MD PhD, Winnipeg, Manitoba, Canada

736 Investigation of Chronic Urticaria with Autoimmune Thyroid Disease and RBL Cell Degranulation Finn A MD, Balakrishan G MD, Reddigari S PhD, Kaplan AP MD, Charleston, SC

737 Case Report: Control of Angioedema with Danazol in a Patient with Normal C-1 Esterase Inhibitor Levels Harris R MD, Beverly Hills, CA

738 Reversal of Acquired C 1 Esterase Inhibitor (CI INH) Deficiency with Splenic Irradiation Carpenter GB MD, Waytes TA MD, Washington, DC; Rochester, MN

739 De-Novo Angioedema Due to Cl-Inhibitor Deficiency Charpin D MD, Birnbaum J MD, Laurent J MD, Vervloet D MD, Tosi M PhD, Marseille, France

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Characterization of Naturally Occuring Pseudoallergens Causing Chronic Urticaria Pfrommer C MD, Bastl R, Vieths S PhD, Ehlers I, Henz BM MD, Zuberbier T MD, Berlin, Germany

Dimephosphon in Treatment of Chronic Urticaria Tsybulkina V MD PhD, Kazan, Russia

ATOPIC DERMATITIS

742 Soluble HLA Class I (sHLA-I) and Food Sensitivity in Children with Moderate to Severe Atopic Dermatitis Moore C MD, Ehlayel M MD, Inostroza J PhD, Mufioz P MD, Leiva L PhD, Hughes J PhD, Sorensen RU MD, New Orleans, LA

743 Lymphocyte Transformation Test (LTT) with Ovalbumine (OV) and House Dust Mite (HDM) in Children with Eczema Van Bever HP, Vereecke I, De Gendt CM, Bridts CH, De Clerck LS, Stevens WS, Antwerp, Belgium

744 Red Cell Fatty Acid Composition in Atopic Dermatitis and Asthma M~ispero JF MD, Y/uiez A MD, Kohan M MD, Catz S PhD, Setton P PhD, Fem~indez M PhD, D'Antuono C PhD, Speziale M PhD, Buenos Aires, Argentina

745 Skin Reactivity to Blomia tropicalis and Euroglyphus maynei in Patients with Atopic Dermatitis in Puerto Rico Montealegre F DVM PhD, Quifiones C MT, Le6n W Bs, Goth K VA, Villa J MD, Garcia M RN, Ponce, Puerto Rico

746 The Incidence of Atopy in Psoriasis Freye HB MD, Litwin C RN, Providence, RI

747 Human IgE Response to Scabies Morgan MS PhD, Arlian LG PhD, Estes SA MD, Dayton, Cincinnati, OH

748 Topical Application of a Platelet Activating Factor (PAF-) Antagonist in Atopic Eczema Schmidt T MD, Abeck D MD, Grosshans E MD, Jablonska S MD, Kragballe K MD, Valquist A MD, Dupuy P MD, Ring J MD, Hamburg, M~inich, Germany," Aarhus, Denmark; Link6ping, Sweden; Strasbourg, France; Warsaw, Poland

749 Lack of Type I Sensitization to Laundry Enzymes Among Consumers in the Philippines Sarlo K PhD, Cormier E PhD, MacKenzie D MD, Scott L PhD, Cincinnati, OH

750 Evaluation of Sensitization to Laundry Enzymes Among Consumers in the Philippines: Results of a Six Month Clinical Study Cormier E PhD, Sarlo K PhD, MacKenzie D MD, Scott L PhD, Cincinnati, OH

751 Patch Testing with Unprocessed Pollen of Gramineae in Patients with Atopic Eczema Darsow U MD, Behrendt H MD, Ring J MD PhD, Hamburg, Munich, Germany

752 Disturbance of Epidermal Barrier Function in Atopy Patch Test Reactions in Patients with Atopic Eczema Gfesser M MD, Rakoski J MD PhD, Ring J MD PhD, Munich, Germany

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CONTACT DERMATITIS

753 Post-Marketing Survey Results for TRUE Test TM, A New Allergen Patch Test Prue JC RPh, Research Triangle Park, NC

754 Group Allergy to Tri- and Ortho-diphenols in a Patient Sensitized by Propyl Gallate Hemmer W PhD, Focke M PhD, Bracun R MD, Wolf S MD, Wantke F MD, GStz M MD, Jarisch R MD, Vienna, Austria

755

756

Contact Dermatitis from Budesonide Nasal Spray Jorgensen RK MD, Reed CE MD, Gleich GJ MD, Wilson C BA, Schroeter AL MD, Rochester, MN

Evaluation of Cutaneous Hypersensitivity to Aluminum by Routine Patch Testing with AIC13 Jarisch R MD, Hemmer W PhD, Wantke F MD, Focke M PhD, GStz M MD, Vienna, Austria

757 Contact Allergy to Euxyl K400® Wolf-Abdolvahab S MD, Bracun R MD, Hemmer W PhD, Focke M Phd, Wantke F MD, GStz M MD, Jarisch R MD, Vienna, Austria

758 Contact Dermatitis to Jojoba Oil and Myristal Lactate/Maleated Soybean Oil Botzi C, Wantke F, Hemmer W, Focke M, G0tz M, Jarisch R, Vienna, Austria

759 Occupational Contact Allergy to Herbicide Aminotrazol Rodriguez Barrera A MD, Alvarez M J, Echechipia S, Sanchez-Palacios A, Sada JL, Pamplona, Spain

MISCELLANEOUS DERMATOLOGY

760

761

Comparison of the Bifurcated Needle with the DermaPIK® and Duotip® for Allergy Skin Testing Corder WT MD, Wilson NW MD, Morgantown, WV

Hi-Receptor Antagonist: Systemic Absorption and Peripheral HI-Blockade Following Administration in Topical Liposome Formulations Simons KJ PhD, Venkataram S PhD, Zheng Y MSc, Simons FER MD, Winnipeg, Canada

762 Effect of Cetirizine on the Inflammatory Cells in Cutaneous Mosquito-Bite Reactions Karppinen A, Rantala I, Vaalasti A, Burtin B, Brummer-Korvenkontio H, Reunala T, Tampere, Helsinki, Finland; Braine-l'Alleud, Belgium

763 A Double-Masked Study on the Need for Adjunctive Steroid Treatment in Vernal Keratoconjunctivitis Patients Treated with Alomide 0.1% Opthamalic Solution or Opticrom 2% Tomazzoli L MD, Scullica L MD, Cespedes C MD, Iruzubieta M, Sans R MD, Secchi A MD, Verona, Messina, Padova, ltaly; Barcelona, Sevila, Madrid, Spain

764 A Simplified Method for Human Conjunctival Allergen Challenge Friedlaender MH MD, Martien A, Friedlaender S MD, Gainesville, FL

765 Alomide 0.1% Versus Sodium Cromoglycate 2% and 4% in Patients with Giant Papillary Conjunctivitis Caldwell M MD, Stewart RH MD, McCulle JP MD, Ostrov CS MD, Houston, Dallas, TX; Minneapolis, MN; New Orleans, LA

766 Should Sesquiterpene Lactone Sensitive Patients Avoid Consuming SL Containing Vegetables? Tjiook SB MD, de Haas R MD, Oei HD MD, Dordrecht, The Netherlands

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Trisomies 9 and 8 Detected by Fluorescence in Situ Hybridisation in Patients with Systemic Mastocytosis Conf'mo-Cohen R, Lishner M, Goldberg A, Feigin M, Amiel A, Mekori YA, Kfar Saba, Israel

Cloning and Sequencing of the cDNA Encoding the Pityrosporum Orbiculare 37 kDa Major Allergen Lindblom L BS, Schmidt M PhD, Hellman U PhD, Zargari A MS, van der Ploeg I PhD, H~'fast B PhD, Scheynius A MD PhD, Stockholm, Uppsala, Sweden

Murine Skin Mast Cells Release Histamine After Stimulation with Vanilloids In Vitro Maurer M MD, Pfrommer C MD, Pans R MD, Eichmtiller S PhD, Henz BM MD, Zuberbier T MD, Berlin, Germany

ASTHMA EPIDEMIOLOGY: RISK FACTORS AND OUTCOMES

770 Wheezing in Non-Hospitalized Infants is Neither Predicted by Atopic Inheritance, Nor Does it Predict Atopic Manifestation in the Second Year of Life Forster J MD, Krebs H MD, Streckert HJ PhD, Werchau H MD, Wahn U MD, German Multicenter Atopy Study Assoc., Tacke U MD, Freiburg, Bochum, Berlin, Germany

771 Is Daycare a Risk Factor for Exacerbation of Bronchial Asthma (BA) German DF MD, Watson R MPH, San Francisco, CA

772 Increasing Trend of Asthma and Allergic Disease in Hong Kong Schoolchildren Leung R MD, Ho SS MD, Chan J MD, Wong G MD, Lau J PhD, Lai CKW MD, Shatin, Hong Kong

773 Factors Associated with Asthma in a Birth Cohort of Children Followed to Six Years of Age Johnson CC PhD, Peterson EL PhD, Ownby DR MD, Detroit, MI

774 The Impact of Eczema in Seattle School Children Cook CK MS, Redding GJ MD, Morray BH, Arrighi HM PhD, Research Triangle Park, NC; Seattle, WA

775 Asthma Deaths in Chicago Levenson T MD, Greenberger PA MD, Lifschultz B MD, Chicago, IL

776 Asthma Mortality in Israel 1971-1990 Katz Y, Livne M, Zerifin, Israel

777 Socioeconomic Status (SES) and Risk Factors for Asthma in Rural Appalachian Children Wilson NW, Corder WT, Morgantown, WV

778 St. Louis Asthma Database Knutson JW, Sussman LK, Slavin RG, Castro M, St. Louis, MO

779 Comparing the Demographics of lnpatients and Outpatients with Asthma Apter AJ MD, Reisine ST, ZuWallack RL, Farmington, Hartford, CT

780 Asthma Mortality Rate and the Sales Amount of MDI in Japan Matsui T MD, Onobori M MD, Baba M MD, Tokyo, Japan

781 Screening of High School Athletes for Exercise Asthma by Free Running Test Randolph C MD, Mattasavage C, Fraser B LPN, Waterbury, CT

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782 Asthma and Air Pollution: Two Major Grass Pollen Allergens Bind to Diesel Exhaust Particles (DEPs) Knox RB PhD, Suphioglu C PhD, Taylor P BSc, Peng JL PhD, Bursill LA PhD, Melbourne, Australia

783 Correlation of Asthma Exacerbations and Environmental Factors in Middle Tennessee: The Importance of Mold Sandidge DR MD, Murray JJ MD PhD, Leftwich RB MD, Nashville, TN

784 The Atopic Profile of Adult Asthmatics Admitted to Hospital in Wellington, New Zealand Fitzharris P MD, Stone L BA, Sawyer G BN, Tohill S BA, Lewis S, Crane J FRACP, Miles J MD, Wellington, New Zealand

785 The Effect of Exposure to Animal Dander in School Dust in Children with Asthma and Rhinitis Hedlin G MD, L0nnkvist K MD, Enander I PhD, Hallden G PhD, van Hage-Hamsten M MD, Stockholm, Uppsala, Sweden

786 Allergy to the Blatella Germanica (Bla g) Cockroach (CR): A Major Risk Factor for Asthma Severity in Adolescents Horowitz E BA, Joyner D MD, Guydon L MD, Malveaux F MD PhD, Togias A MD, Baltimore, MD

787 Correlation of Asthma Admissions with Levels of Environmental Pollutants, Pollen and Viral Outbreaks Quaidoo EA MD, Pulver DW MD, Rochester, NY

788 Agressive Household Cleaning Alone is as Efficient as When Combined with a New Acaricide Improving Dust Mite Allergic Asthmatic Children Bahir A MD, Goldberg A, Confino-Cohen R, Mekori YA, Kfar Saba, Israel

789 The Relationship of Psychological Functioning of the Severe Asthmatic Child (SAC) and Family to Medical Costs Over Four Years After Short Term Residential Rehabilitation (Rhb) Weinstein AG MD, Stapleford J PhD, Faust D PhD, Wilmington, DE

790 Asthma Center Treatment: Prospective Data Korenblat PE MD, Korenblat Hanin M ACSW, Fisher EB PhD, Gaioni SJ PhD, St. Louis, MO

791 A Chart Review of Chest X-rays in Pediatric Asthmatic Patients Tuck J MD, Osborne M MD, Dowling P MD, Kansas City, MO

792 Reduction in Health Care Resource Utilization Associated with Theophylline Schulz RM PhD, Yates WN MS, Columbia, SC

793 Asthma Management: A Survey of Emergency Department (ED) Visits for Wheezing Friday, Jr. GA MD, Khine H MD, Lin MS MD PhD, Caliguiri LA MD, Pittsburgh, PA

794 Intravenous Terbutaline and Continuous Albuterol Nebulizaton Therapy: A Safe Combination Becker JM MD, Coffey S MD, Amin R, Smolij C RN BSN, Goldsmith DP MD, Philadelphia, PA

795 Identification of the High Risk Pediatric Asthma Patient Oyefara BI MD, Taylor L PhD, Louie J BS, Brown T MD, Pawlowski NA MD, Philadelphia, PA

796 Telemetry of Field Spirometry Data to Assist Physician Treatment and Triage of Asthmatic Patients Aquino T BA, Bielory L MD, Tortella B MD, Lavery B MA, Newark, NJ

797 A New Model of Pediatric Asthma Care Delivery Pongracic JA MD, Zachary CY MD, Evans III R C, Chicago, IL

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800

801

802

803

804

805

806

Management of Status Asthmaticus by Pediatric ER and ICU Training Program Directors Becker BA, Leipzig JR, Dykewicz MS, St. Louis, MO

Continuous Inhalation of Isoproterenol (L-type) in the Treatment of Children with Severe Asthmatic Attacks Iikura Y MD, Saito H MD, Capulong MCT MD, Sakaguchi N MD, Inui H MD, Obata T MD, Koya N MD, Uchiyama H MD, Sasamoto A MD, Tokyo, Japan

A Multiple Linear Regression Analysis of Meteorologic Factors (MF) and Emergency Department (ED) Utilization by Patients with Asthma (PwA) in a Rural Setting Krishna J MD, Huskey S, Camp T MD, Peterson RE PhD, Mamlok V MD, Hubbard D MS, Mamlok RJ MD, Lubbock, TX

In-Vitro Assessment of a New Efficient Nebulizer System for Continuous Operation Gutmann W, Knoch M PhD, Wunderlich E, Starnberg, Germany

T-Cell Receptor Vfl Gene Usage in BAL T-Cells in Health and in Asthma Dasmahapatra J, Hodges EA, Redington AE, Krishna T, Boylston AW, Holgate ST, Smith JL, Frew A J, Southampton, Leeds, United Kingdom

Monozygotic Twins as a Model for Study in Asthma Miller ME MD, Leikauf G PhD, Bernstein JA MD, Cincinnati, OH

Prospective Twin Study of IgE Immune Responses in Acute Otitis Media (AOM) Fireman L BA, Casselbrant M MD PhD, Angelini B BSN, Fireman P MD, Pittsburgh, PA

Efficient Transfer and Expression of Genetic Material In Vivo in Rat Lung Using Starburst TM Dendrimer Synthetic Vectors Kukowska-Latallo J PhD, Rymaszewski M BA, Bielinska A PhD, Tomalia D PhD, Baker Jr J MD, Ann Arbor, Midland, MI

HLA and Respiratory Allergy Aguilar D MD, Delgado D MD, Vidal F MD, Mexico City, Mexico

ALLERGENS: TESTING, TECHNOLOGY, AND THERAPEUTICS

807 Serum IgE to Hen's Egg is a Risk Factor for Consecutive Sensitization to Aeroallergens Nickel R MD, Kulig M MD, Forster J MD, Bergmann R MD, Bauer CP MD, Lau S MD, Guggenmoos-Holzmann I MD PhD, Wahn U MD, Berlin, Freiburg, Munich, Germany

808 The Correlation of Allergy History & Skin Test Results Ostro MG MD, Abi-Younes S MD, Bloch KJ MD, Boston, MA

809 Evaluation of the AlaTOP® Allergy Screen McCullough J BA, Blocki S BS, Ownby D MD, Detroit, MI

810 Comparison of a Multiallergen In Vitro Screen to Skin Testing in a Large HMO-Based Allergy Clinic Goldberg BJ MD PhD, Pham T MD, Cocke S MD, Kaplan M MD, Staveren A MD, Lad PM PhD, Los Angeles, CA

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811 Performance of a Fully Automated Enzyme Immunoassay System for the Determination of Allergen-Specific IgE in Serum Li TM PhD, Nayak N PhD, Tung J PhD, Garden Grove, CA

812 Evaluation of the Recombinant Aspergillus Fumigatus Allergen 1 (rAsp f 1) in the Pharmacia CAP System Crameri R, Lidholm J, GrOnlund H, Blaser K, Ismail C, Menz G, Davos Wolfgang, Switzerland; Uppsala, Sweden

813 Total IgE Determinations: Comparison of Results Obtained by Immulite and CAP System Abreu Nogueira JM, Loureiro V, Morais de Almeida M, Rosado Pinto JE, Lisbon, Portugal

814 House Dust Mites and Alternaria in Allergic Rhintis: Role of Allergen Immunotherapy Tarraf H, EI-Hefny A, Ekaldius E, Cairo, Egypt

815 Intravenous Administration of a Potential T Cell Toleragenic Peptide to Cat Sensitive Patients Norman PS MD, Pasatiempo AMG MD, Creticos PS MD, Nicodemus CF MD, Jones NH PhD, Lichtenstein LM MD PhD, Gefter ML PhD, Baltimore, MD; Waltham, MA

816 Efficacy of Dust Mite Allergen Eduction by ePTF-Encasings and Clincal Response in Combination with Specific Immunotherapy Paul KP MD, Kleutke U MD, Wahn U MD, Berlin, Germany

817 The Cat Room Model for Associating Allergen Levels with Asthma Symptoms and Evaluating Treatment Effects of Peptide Therapy Ohman JL MD, Bennett DV PhD, Happ MP PhD, Settles MR BS, Jones NH PhD, Hirani S PhD, Long AA MD, Waltham, Boston, MA

818 Aeroallergen Avoidance in Offspring of Allergic Patients Deuell B MD, Frazer J MD, Alblowich A RN, Rakes G MD, Ingram JM MD, Chang M, Platts-Mills TAE MD, Heymann P MD, Portsmouth, NH; Charlottesville, VA

819 Skin Test Reactivity in Infants and Young Children E1-Falaki M, EI-Hefny A, EI-Beleidy A, Cairo, Egypt

820 House Dust Mite Hypersensitivity in a Group of Asthmatic Children Prieto L MD, Sienra J MD, Del Rio B MD, Mercado V MD, Martinez J PhD, Mexico City, Mexico; Bilbao, Spain

821 Survey of Skin Tests in a Central FL Practice Price GW MD, Bonini LV MD, Spoto AP MD, Tabb WC MD, Lakeland, FL

822 California House Dust Antibodies in the Sera of Allergic Patients in Tabuk, Saudi Arabia: Preliminary Report Somorin AO, A1-Dusari SN, Zaman AU, AI-Masuidi, Tabuk, Saudi Arabia

823 Long-Term Oral Corticotherapy Does Not Alter Skin Test Reactivity Paradis L, Des Roches A, Bougeard YH, Godard PH, Bousquet J, Chanez P, Montpellier, France

824 False Positive Skin Prick Tests with Commercially Available Dog Dander Extracts Caused by Contamination with House Dust Mite Allergens van der Veen MJ, Mulder M, Witteman AM, van Ree R, Aalberse RC, Jansen HM, van der Zee JS, Amsterdam, The Netherlands

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Evaluation of the Reproducibility of Skin Test Measurements by a Computer Imaging Technique Khayamy D MD, Moy J MD, Mariano R RN, Yu B MD, Chicago, IL

Cutaneous Prick Testing with DuoTip-Test Liddle KJ MD, Gilmet GG MD MPH, Baldwin JL MD, Ann Arbor, M1

A Variation in Potency of Two Standardized Dust Mite Extracts Hill J RN, Crawford T LPN, Howard A RN, Kang BC MD, Lexington, KY

IMMUNODEFIClENCY (PART 1)

828 Deficiency of Janus Kinase 3 (Jak3) Protein in Severe Combined Immunodeficiency (SCID) Roberts JL MD, O'Shea JJ MD, Puck JM MD, Buckley RH MD, Durham, NC; Bethesda, MD

829 Elevated TNF-a Associated with Neutropenia in Combined Immunodefciency (CID) Harville TO MD PhD, Winter SS MD, Hanissian GA MD, Gem JE MD, Ware RE MD PhD, Durham, NC; Madison, W1

830 A 3-Year-Old Boy with ZAP-70 Defciency, Thrombocytopenia and Ulcerative Colitis Parry DE MD, Blumenthal J MD, Tomar RH MD, Horowitz SD MD, Elder ME MD PhD, Gem JE MD, Madison, WI; San Francisco, CA

831 Oral Ribavarin for Gastrointestinal Adenovirus in Severe Combined Immunodeficiency Harville TO MD PhD, Tang ML MD PhD, Garcia-Turner AM BS, Gitch JL BS, Miller SE PhD, Durham, NC

832 Gastroesophageal Reflux and Severe Combined Immunodeficiency Boeck A MD, Schiff RI MD PhD, Buckley RH MD, Durham, NC

833 Cytokine Production and IgE in Wiskott-Aldrich Syndrome (WAS) Patients Herrod HG MD, Raby RB MD, Valenski WR BS, Hutchinson SR MT(ASCP), Nastasi KJ MD, Conley ME MD, Memphis, TN

834 Analysis of In Vitro and Serum IgM Production in Wiskott-Aldrich Syndrome (WAS) Patients Nastasi KJ MD, Raby RB MD, Valenski WR BS, Conley ME MD, Herrod HG MD, Memphis, TN

835 Carcinoma in Wiskott-Aldrich Syndrome/Variant (WAS) Hogan MB MD, Krasnick J MD, Wilson NW MD, Chicago, IL; Morgantown, WV

836 Development of Normal T-Cell Function and TCR Repertoire After Post-Natal Thymic Transplantation For DiGeorge Syndrome Markert ML MD PhD, Davis CM BA, Ward FE PhD, Kostyu DD PhD, Buckley RH MD, Schiff SE BA, Watson TJ BS, McLaughlin TM BA, Hale LP MD PhD, Haynes BF MD, Durham, NC

837 Clinical Analysis of Patients with DiGeorge Anomaly Zeffren BS MD, Day NK PhD, Good RA PhD MD, Kornfeld SJ MD, St. Petersburg, FL

838 Cellular Immunodeficiency with Elevated IgE and a New Anomaly of Chromosome 22 Kagan RS MD, Der Kaloustian VM MD, Eydoux P MD, Mazer BD MD, Montreal, Quebec, Canada

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839 Familial Congenital CD4 T-Cell Deficiency: A New Syndrome of Immune Deficiency Dranitzki Z MD, Ulmansky R PhD, Szafer F PhD, Kerem E MD, Freier Z MD, Brautbar C PhD, Rabinowitz R PhD, Naparstek Y MD, Jerusalem, Israel

840 Idiopathic CD4+ T-Lymphocytopenia (ICL) with Systemic Nocardiosis and a Large Population of CD33 CD4" CD8" T Cell Receptor (TCR) ~x/13 + Lymphocytes Venzor J MD, Hua Q MD, Miranda CH, Bressler RB MD, Huston DP MD, Houston, TX

841 Hyper-IgM Syndrome (HIgMs): A B-cell Defect Weiss SJ MD PhD, Zeng F-F MS, Bonagura VR MD, North Hyde Park, NY

842 Expression of CD 40 Ligand in Immunodeficiency with Hyper IgM Due to Congenital Rubella Beausoleil J MD, Schwarz R MD, McGeady SJ MD, Philadelphia, PA

843 Disseminated Pneumocystis carinii in a 5-Year Old Girl with Hyper-IgM Syndrome (HIMS) with Exceedingly High Serum IgM Oftadeh L MD, Keller M MD, Sun N MD, Heiner DC MD, Oh C, Song C MD, Torrance, CA

844 Atypical Presentation of Ataxia-Telangiectasia (AT) with Features of Non-X-Linked HyperlgM (HIGM) Noroski LM MD, Rosenblatt HM MD, Hanson IC MD, Abramson SL MD PhD, Paul ME MD, Shearer WT MD PhD, Houston, TX

845 Parainfluenza Type 3 in a Patient with Hyper IGM (HIM) Nashed MN MD, Assa'ad AH MD, Lierl MB MD, Cincinnati, OH

846 Pneumocystis Carinii Pneumonia (PCP) as Presenting Infection in Patients with Hyper IGM Syndrome Gonzales B MD, King A MD, Leiva L PhD, Sorensen RU MD, Santiago, Chile; New Orleans, LA

847 Cellular and Cytokine Abnormalities in Common Variable Immunodeficiency Grant EN MD, Landay AL PhD, Siegel JN PhD, Kaufman MS, Mosiman VL, Richmond GW MD, Chicago, IL

848 Monocytes From Patients With CVI Provide Optimal Co-Stimulation For Cytokine Secretion Mayer L MD, Stadtmauer G MD, New York, NY

849 Granulomatous Disease in Common Variable Immunodeficiency - Not Sarcoidosis Mechanic LJ MD, Dikman S MD, Cunningham-Rundles C MD PhD, New York, NY

850 Absence of Recurrent Bacterial Infections In Common Variable Immunodeficiency (CVID): Retention Of Functional Antibody Responses Despite Severe Panhypogammaglobulinemia Kalenian M MD, Levinson AI MD, Philadelphia, PA

851 Antibody Deficiency with Normal Immunoglobuline Presenting in Adult Life Alshaar A MD, A1-Assaly H MD, McGeady SJ MD, Philadelphia, PA

852 Gammaglobulinemia Associated to Chromosome 2 Deletion Wheba J MD, Richieri-Costa A MD, Costa-Carvalho BT MD, Carneiro-Sampaio MMS MD, So16 D MD, Naspitz CK MD, Sao Paulo, Brazil

853 Saldino-Mainzer-Like Syndrome with Persistent Panhypogammaglobulinemia and T Cell Dysfunction Fuentes D MD, Hanson IC MD, Abramson SL MD PhD, Rosenblatt HM MD, Shearer WT MD PhD, Houston, TX

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854 Polyarthritis Responsive to Methotrexate (MTX) in X-Linked Agammaglobulinemia LoGalbo PR MD, Ilowhite NT MD, New Hyde Park, NY

855 In Vitro Immunoglobulin Production in Patients with Partial IgA Deficiency (plgAd) Raby RB MD, Barsness KA BS, Hutchinson SR MT (ASCP), Valenski WR BS, Trouy RL MS, Herrod HG MD, Memphis, TN

856 lgG and IgA Subclasses and Anti-IgA Antibodies in 34 IgA Deficient Patients Kirschfink M PhD, Sao Paulo, Brazil

857 Prevalence of Humoral Immunodeficiency in the African-American and Hispanic Populations of East Harlem Lewis M, Mujashiro M, Hunton J, Miller L, Sperber K, New York, NY

858 Transient Hypogammaglobulinemia of Infancy: Long Term Follow-Up McGeady SJ MD, Beausoleil JL MD, Philadelphia, PA

859 Severe Asthma, Difficult Infections, and Mild Hypogammaglobulinemia Lane SR MD, Bigelsen SJ MD, Moorestown, NJ

860 Panhypogammaglobulinemia after Anticonvulsant Therapy Chung CK MD MPH, Billips LG PhD, Schroeder Jr. HW MD PhD, Birmingham, AL

861 Characterization of an Immunodeficiency Manifest by Severe Viral Skin Infections, Eczema, and Asthma Rabin RL, Fuss I, Prussin C, McDyer J, Garraud O, Nutman TB, Fleisher TA, Seder R, Strober W, Holland SM, Bethesda, MD

862 Transplacental Transmission of Serotype-Specific Pneumococcal Antibodies in a Brazilian Population Costa Carvalho BT MD, Carneiro Sampaio MMS MD, So16 D MD, Naspitz CK MD, Leiva L PhD, Sorensen RU MD, Sdo Paulo, Brazil," New Orleans, LA

863 An Algorithm for Clinical and Laboratory Testing in Suspected Primary Immunodeficiency Disease in Infants and Children Davis-Lorton MA, Stadtmauer G, Mayer L, Cunningham-Rundles C, New York, NY

864 Immunogenicity of Hemophihs Influenzae Type B Polysaccharide Vaccine for the Evaluation of Patients With Suspected Immunodeficiency Go RO MD, Schneider LC MD, Boston, MA

865 Pneumococcal Immunization in Patients with Recurrent Infections and in Patients with Primary Immonodeficiency (ID) Syndromes So16 D MD, Costa Carvalho BT MD, Carneiro Sampaio C MMS MD, Leiva L PhD, Naspitz CK MD, Sorensen RU MD, Sao Paulo, Brazil," New Orleans, LA

866 Characterization of Specific Antiobody Responses to Diphtheria/Tetanus Booster Vaccination in Pediatric Patients Evaluated for Immune Deficiency McCusker C MD, Somerville W, Grey V PhD, Mazer B MD, Montreal Canada

867 Delayed Type Hypersensitivity (DTH) Skin Testing (SKT) for the Evaluation of Cellular Immunity: Normal Responses For Adult Men and Women Heisser A MD, DeGuzman R MD, Brooks J RN, Veltri N RN, Carregal V MD, Smith LS MD, Carpenter GB MD, Engler RJM MD, Washington, DC

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868 Measurement of CD69 by Flow Cytometry is a Rapid and Efficient Substitute for 3H-Thymidine Incorporation in the Assessment of Nitrogen or Anti-CD2/CD2R Induced T Cell Proliferative Capacity in Normal Individuals Mardiney III M MD, Fleisher TA MD, Bethesda, MD

869 Cytokine Production in the Hyper-IgE Syndrome Esswein LA MD, Bader SA, Chatila TA MD, St. Louis, MO

870 Development of Candida Endocarditis in a Patient with Hyper lgE Syndrome (HIE) Yates AB MD, Mehrotra D MD, Moffitt J MD, Jackson, MS

871 Clinical & Immunopathological Aspects of Hyper-IgE Syndrome (HIE) Moin M MD, Farhoudi A MD, Tehran, 1ran

872 Thymic Regrowth in a Patient with Chronic Granulomatous Disease on IFN-T Kobrynski LJ MD, Atlanta, GA

873 Trichosporon Inkin Pulmonary Abcesses Presenting as a Perforating Chest Wall Mass in a Child with Chronic Granulomatous Disease (CGD) Stadtmauer GJ MD, Piwoz J MD, Bottone E PhD, Weitzman I PhD, Cunningham-Rundles C MD, New York, NY

874 Multifocal Osteomyelitis Due to Pseudomonas Gladioli in a Patient with Autosomal Recessive Chronic Granulomatous Disease Smith CA MD, Sullivan K MD PhD, Pawlowski NA MD, Greene JM MD, Brown T MD, Yip AG MD, Rae J, Curnutte J MD, Douglas SD MD, Philadelphia, PA

875 Obstructive Hydrocephalus Caused by Basilar Meningitis in a Patient with Chronic Granulomatous Disease (CGD) Zaitoun FH MD, Wray BB MD, Cox FE MD, Figueroa RE MD, Flannery MA MD, August, GA

876 Differential Expression of CD 18/CD1 l afo/c on Lymphocytes and Neutrophils in Leukocyte Adhesion Deficiency Type-I (LAD-l) Watkins CM MD, Harville TO MD PhD, Schiff SE BS, Schiff RI MD PhD, Durham, NC

877 Complement Deficiencies in Patients Affected by Meningitis Caused by N. meningitidis Grumach AS MD, Campeas A MD, Diogo CL BS, Raymundo MC MD, Oliveira LC BS, Carneiro MSS MD, Kirschfink M PhD, Sao PSulo, Brazil

878 A Novel Familial C2 Abnormality Seggev JS MD, Giclas P PhD, Las Vegas, NV; Denver, CO

879 Properdin Deficiency: Rare Presentation with Meningococcal Osteomyelitis and Arthritis Rottem M MD, Shiloach E MD, Schlezinger M MD, Afula, Zrifin, Ashkelon, Israel

880 Immunomodulatory Effects of Levamisole in Chronic Fatigue Syndrome Polasani R MD, Schwartz SA MD PhD, Buffalo, NY

I M M U N O D E F I C l E N C Y (PART 2) - HIV

881 Upregulation of HIV replication by CD4 Crosslinking Dalal H MD, Oyaizu N MD, Soe T MD, Paul M PhD, Bakshi S MD, Pahwa S MD, Manhasset, NY

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892

Dioxin Increases HIV-1 Replication By Activating NF-kB and HIV-1 Long Terminal Repeat (LTR) Gupta S MD PhD, Kim CH PhD, Gollapudi S PhD, Irvine, CA

Objective Measures of Allergic Disease in Children With HIV Infection Bacot BK MD, Navarro M MD, Abramson SL MD PhD, Hanson IC MD, Kline MW MD, Rosenblatt HM MD, Shearer WT MD PhD, Houston, TX

Morbidity of Respiratory Virus Infections in HIV-Exposed and HIV-Infected Children Love Jr JT MD PhD, Kline MW MD, Demmler G MD, Bohannon B RN BSN, Shearer WT MD PhD, Houston, TX

Differential Expression of Tat Associated Protein Desai K MD PhD, Houston, TX

The Stress Hormone, Cortisol, Synergizes with HIV-1 Gp-120 to Induce Apoptosis of Normal Human Peripheral Blood Mononuclear Cells (PBMC) Nair MPN PhD, Hou J MD, Sweet A MS, Schwartz SA MD PhD, Buffalo, NY

HIV-1 Nef Protein Induces Interleukin-10 Production in Peripheral Blood Mononuclear Cells and H9 Cell Line Brigino E MD, Haraguchi S PhD, Koutsonikolis A MD, Owens U, Good RA PhD MD DSc, Day NK PhD, St. Petersburg, FL

Positive Direct Antiglobulin Test (DAT) and Autoimmune Hemolytic Anemia (AIHA) in Children with Vertically Acquired HIV Infection Sinclair JP MBChB, Rosenblatt HM MD, Hanson IC MD, Kline MW MD, Rossmann S MD, Paul M MD, Abramson SL MD PhD, Shearer WT MD PhD, Houston, TX

CD45RO and CD45RA Peripheral Lymphocyte Subsets in HIV-1 Patients Del Giacco GS MD, Arangino V MD, Lombardini S DSc, Manca E DSc, Ambrosini B DSc, Di Martino L DSc, Del Giacco S MD, Manconi PE MD, Cagliari, Italy

Nasal Epithelial Alterations are Associated with Chronic Nasal Symptoms in HIV Infection Clarin E MD, Lee M MD, Lin RY MD, New York, NY

EBV Associated Leiomyosarcoma Metastasizing to Bone Goodman B MD, Paul ME MD, Hanson IC MD, Rosenblatt HM MD, Abramson SL MD, Shearer WT MD PhD, Houston, TX

Effect of Exercise on Thl and Th2 Type Cytokine Production in HIV-1 Infected Subjects Smith JK MD, Krishnaswamy G MD, Chi D PhD, Dykes R BS, Reynolds S BS, Berk S MD, Johnson City, TN

I M M U N O D E F I C I E N C Y (PART 3) - IVIG

893 Modulation of Activated B and T Cell Tyrosine Phosphorylation by IVIG Melamed I MD, Gelfand EW MD, Denver, CO

894 Sumatriptan Succinate is Effective Treatment for Headache Induced by Intravenous Gammaglobulin (IGIV) Wasserman RL MD PhD, Dallas, TX

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895 Transmission of Hepatitis C Virus Via Intravenous Immunoglobulin Infusions in Patients with Common Variable Immunodeficiency Davis-Lorton MA MD, Cunningham-Rundles C MD, New York, NY

896 Hepatitis C Virus (HCV) Infection in Common Variable Immunodeficiency (CVID) Associated with IVIG Fasano MB MD, Gilliam III J MD, Peters R MD, Prabhakara H MD, Winston-Salem, NC

897 The Four Year Experience with Intravenous Gamma Globulin at a Tertiary Medical Center DeGuzman R MD, Rodriguez R MD, Bernton E MD, Auth D PharmD, Green D PharmD, Smith L MD, Engler RJM MD, Washington, DC

898 Metabolic and Hematologic Changes after Different IVIG Infusion Rates Carneiro-Sampaio MMS MD, Costa-Carvalho BT MD, So16 D MD, Sorensen RU MD, Naspitz CK MD, Sao Paulo, Brazil," New Orleans, LA

899 Benign Eczematous Eruption Following High Dose Intravenous Immunoglobulin Therapy Pence RS MD, Beard JS MD, Engler RJM MD, Benson PM MD, Davis WS MD, Carregal VA DO, Washington, DC

900 Hyperthyroidism and Elevated Immune Thyroid Stimulating Globulin (ITSG) Following High Dose Intravenous Immunoglobulin Therapy Buckley CE MD, Ellis GJ MD, Durham, NC

901 Hemiplegia Following IVIG Infusion in a 4-Year-Old Girl with Combined Immunodeficiency (ID) Sarinho E MD, Costa Carvalho BT MD, Carneiro Sampaio MMS MD, Sole D MD, Sorensen RU MD, Sao Paulo, Brazil," New Orleans, LA

CYTOKINES AND IMMUNE MECHANISMS

902 Interferon Alpha Modulates Proliferation and Production of Eosinophilopoietic Cytokines by Peripheral Blood Mononuclear Cells and T-Cell Clones Krishnaswamy G, Srikanth S, Huang SK, Kalbfleisch J, Smith JK, Chi DS, Johnson City, TN; Baltimore, MD

903 Distinct Cytokine Profiles Among Subjects With Immediate and Delayed Hypersensitivity to Trichophyton Tonsurans Slunt JB BSc, Taketomi EA MD PhD, Woodfolk JAMB ChB, Platts-Mills TAE MD PhD, Charlottesville, VA; Uberlandia, Brazil

904 CD8 + T Cells from Allergic Patients Produce IL-4 and Enhance IgE Synthesis In Vitro Meissner N MD, Kussebi F, Coutelle J, Baumgarten C MD, Ratti H MD, Heuser Ch PhD, Renz H MD, Basel, Switzerland; Berlin, Germany

905 Adenovirus EIA-p300 Binding Blocks Interferon-Stimulated Gene Expression Routes J MD, Li H PhD, Bayley S PhD, Ryan S, Klemm D PhD, Denver, CO

906 CD40 Mediated Transcriptional Activation of the Human Lymphotoxin Gene Depends on NF-kB Activation Worm M MD, Geha RS MD, Boston, MA

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907 In Vitro Production of IFN-r, IL-4, IL-10, IL-12, IL-13 and IgE in Asthmatic Children Hsieh KH, Chou CC, Chiang BL, Taiwan, Republic of China

908 Downregulation of Lymphocyte Proliferation and IL-4 Production by Caseins Hydrolysed with Intestinal Bacterial Enzymes Siitas Y MD, Hurme M MD, Isolauri E MD, Tampere, Finland

909 Mucosal Cytokines in Allergic Airway Disease May Be Moved Into the Lumen Through a Plasma Exudation Process Linden M, Andersson E, Andersson M, Greiff L, Svensson C, Alkner U, Persson CGA, Lund, Sweden

910 Culture Conditions Modify the Thl-Th2 Cytokine Pattern of Human T Cell Clones Lagier B, Mautino G, Rabesandratana H, Bousquet J, P6ne J, Montpellier, France

911 Allergen Driven lnterleukin-4 Production by Human T Cell Lines Hermanoff MH MD, Khare G MD, Tilles S MD, Rosenwasser LJ MD, Denver. CO

912 Dexamethasone Inhibits Gene Expression and Production of Both TH1 and TH2 Cytokines from Peripheral Blood Mononuclear Cells Chi DS, Srikanth S, Hall K, Smith JK, Krishnaswamy G, Johnson City, TN

913 VLA-4 Expression on Allergen, Tetanus and Candida T Cell Lines Tarkowski M PhD, Pacheco K MD, Katlan M MD, Rosenwasser LJ MD, Denver, CO

914 Cytokine Expression in Mice Tolerized to House Dust Mite Using Cholera Toxin B Subunit Clark J MD, Shen T MD, Suzuki M MD, Cheng KC PhD, Yoo TJ MD PhD, Memphis, TN

915 Clonal Diversity of IL-4 and IL-13 Expression in Human Allergen-Specific T Lymphocytes Kleine-Tebbe J MD, Essayan DM MD, Han WF MD, Li XM MD, Xiao HQ MD, Huang SK PhD, Baltimore, MD

916 IL-lb Appears to Have a Predominant Role in the Regulation of IL-8 Expression in Hyaline Membrane Disease (HMD) Kwong KY MD, Cayabyab R MD, Randhawa I, Lecart C MD, Stotts CL DO, Minoo P PhD, deLemos RA MD, Jones CA MD, Los Angeles, CA

917 The Inhibitory Effects of the Flavonoid Quercetin on Endotoxin (LPS)-Stimulated Production of Tumor Necrosis Factor-~ (TNF-cx) by Normal Human Peripheral Blood Mononuclear Cells (PBMC) Middleton E MD, Nair MPN PhD, Kandaswami C PhD, Schwartz SA MD PhD, Buffalo, NY

918 Regulation of IgE Production by Anti-IL-4 in Mouse Asthma Model Zhou CY, Crocker IC, Romero FA, Bewtra AK, Townley RG, Omaha, NE

919 Preliminary Competition Studies on Interactions of Plasma Macroglobulins and Specific Autoantibodies to Cytokines with TNFct and IFNcz2 Makrushina IV BS, Zorin NA MD, Zhabin SG MD, Pustoshilova NM PhD, Zakabunin AI PhD, Gur'ev VP BS, Gorin VS PhD, Musatov MI PhD, Novokuznetsk, Russia

920 Serum Concentrations of Autoantibodies (AAT) Against TNFa in Normal Adults and Patients with Exsudative Pleurisy Zhabin SG MD, Zorin NC MD, Makrushina IV BS, Pustoshilova NM PhD, Zakabunin AI PhD, Khanin AI MD, Varin AA BS, Mustatov MI PhD, Novokuznetsk, Russia

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921 Circadian Rhythm in Serum Interleukin-6 Soluble Receptor (IL6sR): Temporal and Functional Relationship to IL6 Roitman-Johnson B BS, Sothern RB PhD, Kanabrocki EL PhD, Yager JG BA, Corcoran K BS, Fuerstenberg RK BS, Weatherbee JA PhD, Nemchausky BM MD, Scheving LE PhD, Minneapolis, MN; Hines, IL; Little Rock, AR

922 Immunohistochemical Study of Cytokine Producing Cells in Peyer's Patch and Intestinal Lamina Propria of Ovalbumin (OVA)-Sensitized BALB/c Mouse Vinuesa MA MD, Tanaka Y MD, Matsushita T MD, Hakugawa J MD, Yoshida H MD PhD, Galimany J MD, Rosario, Argentina; Nagasaki, Japan

923 Relationship Between Interleukin-8 (IL-8) and Neutrophil Adhesion Molecules in Rheumatoid Arthritis (RA) De Gendt CM MD, De Clerck LS PhD, Bridts C MT, Van Osselaer N PhD, Stevens W PhD, Antwerpen, Belgium

924 The Effect of Recombinant Interferon Gamma on IgE Synthesis in Adult Asthmatic Patients Blaziene A MD, Mauricas M PhD, Vilnius, Lithuania

T-CELLS AND THE ALLERGIC RESPONSE

925 T Cell Myocyte Interactions in Airway Inflammation Pur6 E PhD, Reitz H BA, Peters SP MD PhD, Albelda SM MD, Panettieri RA MD, Lazaar AL MD, Philadelphia, PA

926 Recognition of Individual Human Cytomegalovirus (HCMV) Proteins by HCMV-Specific Class I MHC Restricted Cytotoxic T Cells (CTL) Boppana SB MD, Britt WJ MD, Birmingham, AL

927 Class I MHC and TAP-1 Down-Expression in HPV Infected Papillomas: Mechansim for Evasion of CTC Recognition Vambutis A MD, Steinberg BM PhD, Bonagura VR MD, New Hyde Park, NY

928 Restricted TCR Va and VI3 Usage in HDM Induced Allergic Sensitivity in Mice Cheng KC PhD, Suzuki M MD, Krug MS PhD, Clark J MD, Yoo TJ MD PhD, Memphis, TN

929 Atopic and Non-Atopic Individuals Show a Different T-Cell Proliferative Response to Grass Pollen Allergens WUrtzen PA, Arnved J, Ipsen H, Sparholt SH, H~rsholm, K~benhavn, Denmark

930 Histamine Dependent Regulation of T- and B- Lymphocytes in Patients with Atopic Diseases Bereznaya N MD PhD, Kotova S MD PhD, Kiev, Ukraine

IMMUNE MECHANISMS IN DISEASE

931 Differential Effects of Staphylococcal Toxic Shock Syndrome Toxin-1 (TSST-1) on B Cell Apoptosis Versus Activation Hofer MH MD, Newell K PhD, Leung DYM MD PhD, Denver, CO

932 Previous Oral Feeding of Latex Allergens Down Regulates IgE and Eosinophil Responses in Mice Xia JQ MD, Kelly KJ MD, Kurup VP PhD, Choi H MD, Fink JN MD, Milwaukee, WI

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Oral Tolerance Can Prevent Th2 Cell-mediated Allergic Inflammation in Mice Nakao A MD, Kasai M MD, Nakajima H MD, Kurasawa K MD, Iwamoto I MD, Chiba, Japan

Familial Patterns of Allergen Sensitivity Blumenthal MN MD, Drury D RN, Blumenthal JE MD, Rich SS PhD, Minneapolis, MN

Familial Aggregation of IgE and Correlation with Allergen Sensitivity Rich SS PhD, Nguyen HN, Drury D RN, Blumenthal MN MD, Minneapolis, MN

Analysis of Multiplex Families Containing Asthma Using Pooled DNA Analysis Brott MJ BS, Flanders DJ BS, Oetting WS PhD, King RA MD PhD, Blumenthal MN MD, Minneapolis, MN

Familial Aggregation of BHR Wahid R MD, Rich SS PhD, Hadaway L RT, Blumenthal MN MD, Minneapolis, MN

Antigen-Specific Induction of Airway Inflammation and Hyperreactivity in Sensitized Mice Li XM MD, Wills-Karp M PhD, Huang SK PhD, Baltimore, MD

Prevention of Hearing Loss in EAE Mice Using Antibody Therapy Suzuki M MD, Cheng KC PhD, Krug MS PhD, Yoo TJ MD PhD, Memphis, TN

Effect of Sulfated Polysaccharides on L-selectin (Leu-8) and CD1 lb/Cdl8 (leu-15) Expression on Polymorphonuclear Leukocytes (PMNs) Van Osselaer N, De Clerck LS, Bridts CH, Herman AG, Stevens WJ, Antwerp, Belgium

A Chimeric IgE Antibody Against a Tumour Associated Antigen Mediates Activation of Basophils and Platelets in vitro Daniel BE PhD, Coney LR PhD, Marsh PJ PhD, Chan C, Shi J, Mackay GA PhD, Hide M MD, Joseph M PhD, Capron M PhD, Gould HJ PhD, London, England; Centocor, Philadelphia; Lille, France

Inter-Relationship Between CD30 Positive Lymphocytosis, Hypereosinophilia, and Elevated IgE in Systemic Parasitosis Murali MR MD, Thakur BI( MD, Volkman D MD, Stony Brook, NY; Toledo, OH

POSTER SYMPOSIUM TUESDAY, MARCH 19, 1996

2:00 PM TO 5:00 PM

ALLERGENS: CLONING TO CLINIC Moderators: Peyton Eggleston, M.D. and Martin Chapman, M.D.

943 A Major Blattella Cockroach Allergen Has Significant Tandem Repeated Structures That Bind IgE Helm RM, Cockrell G, Stanley S, Burks AW, Brenner R, Bannon G, Little Rock, AR; Gainesville, FL

944 Molecular and Immunologic Studies of a Major German Cockroach Allergen: Blattella germanica Glutathione-S-transferase (Bla g 5) Arruda LK MD, Vailes LD MS, Chapman MD PhD, Charlottesville, VA

945 Cockroach Allergen (Bla g 1) in School Dust Sarpong SB MD, Wood RA MD, Eggleston P MD, Chicago, IL; Baltimore, MD

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946 Molecular Cloning of a 41kD Alternaria Allergen Sanchez H BS, Bush RK MD, Madison, WI

947 Characterization of Recombinant Alternaria alternata Major Allergen Alt a 1 Expressed in Pichia Pastoris De Vouge MW PhD, Burton M BSc, Vijay HM PhD, Ottawa, Canada

948 Is Dust Sampling a Good Surrogate for Exposure to Airborne Fungi? Chew G, Muilenberg M, Gold D, Burge HA, Boston, MA

949 Assaying Inhalable Allergen Exposures Using a Mini-Cascade Impactor Gandhi R MD, Lewis R PhD, Dixit A PhD, Slavin R MD, Wedner HJ MD, St. Louis, MD

950 Sequence and IgE-Binding of a New Recombinant Allergen from Blomia tropicalis Caraballo L MD, Puerta L MSc, Jim6nez S LB, Avjiouglu A PhD, Marsh D PhD, Martinez B MSc, Cartagena, Colombia; Baltimore, MD

951 In Vivo Cross Reactivity Between IgE Ab to Blomia and Dermatophagoides spp and to the Recombinant Group 5 Allergens Among Mite Allergic Patients Living in the UK Smith A MD, Green R MD, Custovic A MD, Woodcock A MD, Arruda K MD PhD, Chapman M PhD, Manchester, United Kingdom; Charlottesville, VA

952 Immunological Activity of Recombinant Der p 2 and Der f 2 Lapalme Y BSc, Valet JP PhD, Boulanger J MSc, Boutin Y PhD, Brunet C PhD, Lavoie A MD, B6dard PM MD, H6bert J MD, Ste-Foy, Canada

953 Determining Compliance with Environmental Controls Leyvas EA LVN, Bartz CR RN, Simon RA MD, La Julia, CA

954 Role of the Mattress-Bases in Dwelling Mite Infestation Pauli G, de Blay F, Bessot JC, Ott M, Gries P, Strasbourg, France

955 Assessment of Airborne Fel d I Concentrations Using an Amplified ELISA Larsson PH MSc, Malmberg P MD PhD, Wickman M MD PhD, Stockholm, Sweden

956 Concentrations of Airborne Fel d 1 In Special Daycare Centres for Atopic Children Egmar AC RN, Emenius G EHO, Larsson PH MSc, Malmberg P MD PhD, Wickman M MD PhD, Stockholm, Sweden

957 Fel d I Levels in Wellington Primary Schools and on Children's Clothing Patchett KL, Lewis S, Wickens K BA, Crane J FRACP, Fitzharris P MD, Wellington, New Zealand

958 Cloning and Analysis of Different Isogenes Encoding Bet v 1 Isolated from Pollen of North American Birch Boutin Y MD, Labourdette R BSc, Boulanger J MSc, H6bert J MD, Ste. Foy, Canada

959 Overexpression of Recombinant Phi p 5 Isoallergens in Escherichia coli Wissenbach M PhD, Klysner S PhD, Spangfort M PhD, Ipsen H Msc, Horsholm, Denmark

960 Identification of Snow-Crab Antigens in Air Sampling of a Production Plant Chr~tien P MD, Brassard R RT, Chiquette C RT, Malo J MD, Cartier A MD, McCants M RT, Lehrer S PhD, Baie-Comeau, Montreal, Canada; New Orleans, LA

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961

962

Recovery of Peanut Allergens from Ventilation Filters of Commercial Airliners Jones RT BS, Stark DF MD, Sussman GL MD, Yunginger JW MD, Rochester, MN; Vancouver, Toronto, Canada

Ten Minutes in a Clothes Dryer Kills All Mites in Blankets Miller JD MD, Miller A BA, Ridgefield, CT

ORAL SESSION TUESDAY, MARCH 19, 1996

2:00 PM TO 4:00 PM

IMMUNOPATHOGENESIS OF ALLERGIC SKIN RESPONSES Moderators: Ernest Charlesworth, M.D. and Lisa Beck, M.D.

963 2:00 pm In Vivo Expression of Interleukin-12 and Interleukin-13 in Atopic Dermatitis Naseer T, Hamid QA, Minshall EM, Song YL, Boguniewicz M, Leung DYM, Montreal Canada; Denver, CO

964 2:12 pm Dichotomy of Blood and Skin Derived Interleukin-4 Producing Nickel Specific T-Cells and Restricted VI3 Repertoire in Allergic Contact Dermatitis Werfel T, Hentschel M, Kapp A, Renz H, Hannover, Berlin, Germany

965 2:24 pm Eosinophil Cationic Protein in Atopic Dermatitis and Urticaria Montoro A, Chivato T, Laguna R, Baeza M, Zubeldia J, Rubio M, Madrid, Spain

966 2:36 pm Assessment of Autoimmunity in Chronic Urticaria Patients Tong L PhD, Balakrishnan G MD, Kochan J PhD, Kaplan AP MD, Stony Brook, NY; Nutley, NJ

967 2:48 pm Association of Reduced NF-ATp Binding at the IL-4 Promoter Element CLE0 and High IgE Levels in Severe Atopic Eczema Walchner M MD, Wierengal EA PhD, Meurer M MD, Kind P MD, Plewig G MD, Messer G MD, Munich, Germany," Amsterdam, The Netherlands

968 3:00 pm Ovomucoid-Specific CD8 + TH2-Like Cell Lines in Atopic Dermatitis Patients (AD) with Egg Allergy Sampson HA MD, Rowe J BA, Eigenmann PA MD, Leung DYM MD PhD, Huang SK PhD, Baltimore, MD; Denver, CO

969 3:12 pm Cutaneous Injection of RANTES Causes Eosinophil (EOS) Recruitment: Comparison of Nonallergic (NA) and Allergic (A) Human Subjects Beck L MD, Stellato C MD, Dalke S BA, Leiferman K MD, Bickel C MA, Hamilton R PhD, Rosen H MD PhD, Bochner B MD, Schleimer R PhD, Baltimore, MD; Rochester, MN," Rahway, NJ

970 3:24 pm Role of Food Hypersensitivity in Mild to Severe Atopic Dermatitis Hiegel A RN, James JM MD, Wilson G RN, Burks AW MD, Little Rock, AR

971 3:36 pm Modulation of the Histamine Releasing Activity (HRA) Present in the Serum of Patients with Chronic Idiopathic Urticaria (CIU) Valenzano M, Zweiman B MD, Atkins PC MD, Philadelphia, PA

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972 3:48 pm Recruitment of High Affinity IgE Receptor (FceRI)-Bearing Cells in Allergen-Induced Skin Late Phase Reactions Taborda-Barata L MD, Grant JA MD, Humbert M MD, Barkans J BSc, Ying S MD, Kay AB MD, London, United Kingdom; Galveston, TX

ORAL PRESENTATION SYMPOSIA TUESDAY, MARCH 19, 1996

3:00 PM TO 5:00 PM

IMMUNE DEVELOPMENT AND REGULATION Moderators: Susan MacDonald, M.D. and Arnold Levinson, M.D.

973 3:12 pm Anergy Induction in Cloned Phospholipase A2-Specific T Cells of Th2 Functional Phenotype Faith A, Akdis AC, Blaser K, Davos, Switzerland

974 3:24 pm Successful Immunotherapy with T-cell Epitopes of Bee Venom Phospholipase A2 (PLA) in Patients with Bee Venom (BV) Allergy Mt~ller U, Fricker M, Akdis AC, Carballido J, Blaser K, Bern, Davos, Switzerland

975 3:36 pm Constitutive Cytokine mRNA Production In Human Post-Natal Thymus: RT-PCR Analysis of Cellular Subsets Sundy JS MD PhD, Patel DD MD PhD, Whichard LP, Lager PJ, Haynes BF MD, Durham, NC

976 3:48 pm Formation of Germinal Centers (GC) Is Absolutely Dependent on Lymphotoxin-ct (LTct) and Type I TNF Receptors Chaplin DD MD PhD, Matsumoto M MD PhD, St. Louis, MO

977 4:12 pm Expression of Unique Cell Surface Proteins on B Cells of Patients with Severe Combined Immunodeficiency (SCID) Schiff SE BS, Buckley RH MD, Durham, NC

978 4:24 pm Platelet-Activating Factor Blocks Apoptosis and the Inhibition of Immunoglobulin Synthesis Induced by Crosslinking of the Surface IgM Receptor in a Human B Lymphoblastoid Cell Line Toledano B, Noya F, Bastien Y, Mazer B, Montreal, Quebec, Canada

979 4:36 pm Down-Regulation of Human B-Cell Antigen Receptor Signaling by Fc Receptor Cross-Linking Rabinovitch N MD, Patel HR PhD, D'Ambrosio D PhD, Cambier JC PhD, Gelfand EW MD, Denver, CO

980 4:48 pm bcl-x Rather Than bcl-2 Promotes Cell Survival During Centrocyte Selection in the Germinal Center Druey KM, Tuscano JM, Riva A, Pena J, Thompson CB, Kehrl JH, Bethesda, MD

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LATEX ALLERGY Moderators: Jay Slater, M.D. and Gordon Sussman, M.D.

981 3:12 pm Epitope Analysis of a Major Latex Allergen, Hevein Preprotein Beezhold DH PhD, Kostyal DA PhD, Sussman GL MD, Sayre, PA; Toronto, Canada

982 3:24 pm Isolation and Identification of Hevein as a Major IgE-Binding Polypeptide in Latex from Hevea Brasiliensis Chen Z PhD, Posch A PhD, Raulf-Heimsoth M PhD, Baur X MD, Bochum, Germany

983 3:36 pm Characterization and Standardization of a Latex Extract Wikborg T PhD, Johansen N MSc, H~rsholm, Denmark

984 3:48 pm Latex and Cow's Milk Casein Allergens in 31 Latex Gloves Makinen-Kiljunen S MSc, Turjanmaa K MD, Alenius H MSc, Reunala T MD, Palosuo T MD, Helsinki, Tampere, Finland

985 4:12 pm Quantitation of Airborne Latex Allergen Produced by Bursting and Snapping Latex Gloves Abbosh J MD, Ownby D MD, McCullough J BA, Detroit, MI

986 4:24 pm Resolving Discordant Clinical History and Latex IgE Antibody Test Results by a Latex Glove Provocation Hamilton RG PhD, Adkinson Jr NF MD, Baltimore, MD

987 4:36 pm The Effect of Avoidance on the Natural History of Latex Rubber Allergy Zeldin RK MD, Hamilton RG PhD, Adkinson Jr NF MD, Baltimore, MD

988 4:48 pm Latex Contamination in Pencillin Determinants for Skin Testing May Induce False Positive Results Terrados S MD, Blanca M MD, Fernandez J MD, Vega JM MD, Granada, Malaga, Elche, Spain

THEMATIC POSTER SESSION TUESDAY, MARCH 19, 1996

6:30 PM TO 8:30 PM

THE NASAL AIRWAYS: CHALLENGES OF THE '90'S

989 Allergy Impairment Questionnaires: Validation Studies Reilly MC MA MPh, Tanner LA RPh MPh, Meltzer EO MD, Waccabuc, NY; Kansas City, MO; San Diego, CA

990 The Prevalence and Impact of Allergic Rhinitis Among Teenagers Arrighi HM, Cook CK, Redding GJ, RTP, NC; Seattle, WA

991 The Relationships Between Nasal Hyperreactivity, Quality of Life (QOL) and Nasal Symptoms in Perennial Allergic Rhinitis van Wijk RG, de Graaf-in't Veld C, Koenders S, Garrelds IM, Rotterdam, The Netherlands

992 Leukocyte Influx After Capsaicin (CAPS) Nasal Challenge is a Dose Dependent Phenomenon Sanico AM MD, Atsuta S MD, Togias A MD, Baltimore, MD

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993 The Nasal Response to Hyperosmolar Saline (HS) is Inhibited by Capsaicin Treatment Lai G BS, Philip G MD, Togias A MD, Baltimore, MD

994 Comparison of Natural and Induced Cold Models for the Study of Nasal Congestion, Rhinorrhea, and Secretion Riker DK PhD, Witek TJ DrPH, Turner RB MD, Charleston, SC

995 Seasonal Variations in Mediator Levels in Nasal Lavage Fluid of Rhinitic Patients Mainprice B, Campbell AM PhD, Lebel B PhD, Bousquet J MD, Montpellier, France

996 Objective Assessment of the Allergic Reaction in Seasonal Rhinitis Nielsen LP MD, Bierke T MD, Pedersen B MD, Christensen MB MD, Rasmussen TR MD PhD, Dahl R MD PhD, Aarhus, Denmark

997 Nasal Epithelial and Leukocyte Patterns in Allergic Disease: a Study of Mucosal Cytology Specimens Obtained by 2 Different Methods Lin RY MD, Clarin E MD, Lee M MD, Menikoff H MD, New York, NY

998 The Interaction of Lysozyme with Proteoglycans: Implications for its Antibacterial Activity and its Allergenic Potential Josephson AS MD, Drew H MS, Brooklyn, NY

999 Prophylactic Use of Topical Triamcinolone Acetonide Nasal Inhaler in Patients with Seasonal Allergic Rhinitis Storms W MD, Bernstein D MD, LaForce C MD, Pearlman D MD, Proud D PhD, Kagey-Sobotka A PhD, Lim J MD, Creticos P MD, Colorado Springs, Englewood, CO; Cincinnati, OH; Raleigh, NC; Collegeville, PA; Baltimore, MD

1000 Triamcinolone Acetonide Nasal Spray (T) by vs Loratadine Tablets (L) vs T+L in Patients with Spring Pollen Allergic Rhinoconjunctivitis (RC) Gold M MD, Small P MD, Patel P MD, Houle PA MD, Yang W MD, Schulz J MD, Arkinstall W MD, Lavoie A MD, H6bert J MD, Drouin M MD, Lee D MD, Phillips R PhD, Sp6nard J Phi), Brampton, Ontario, Canada

1001 Patient Satisfaction with Seasonal Allergic Rhinitis Therapy in a Clinical Trial Comparing Fluticasone with Loratadine Schenkel E MD, Cox F PhD, Goodwin B, Picone F MD, Aaronson D MD, Reed K, Cook C, Rogenes P PhD, Anschuetz G, Easton, PA; Research Triangle Park, NC

1002 Comparison of Once-Daily Triamcinolone Acetonide Aqueous Nasal Spray and Twice-Daily Beconase AQ® for the Treatment of Seasonal Allergic Rhinitis Due to Ragweed LaForce C MD, Hampel F MD, Kiechel F MD, Lumry W MD, Murray JJ MD, Furst JA BS, Simpson B BS, Smith JA MD, Raleigh, NC; New Branunfels, Dallas, TX," Lincoln, NE; Nashville, TN; Collegeville, PA

1003 Triamcinolone Acetonide Nasal Spray (T) vs Fluticasone Propionate Aqueous Nasal Spray (F) in Patients with Seasonal Allergic Rhinitis Small P MD, Houle PA MD, Day J MD, Briscoe M MD, Gold M MD, Ham Pong AJ MD, Mandl MAJ MD MSc, Brodarec I MD PhD, Sp6nard J PhD, Phillips R PhD, Montrdal, Cap-de-la-Madeleine, Kingston, Brampton, Ottawa, Vancouver, Yarmouth, Canada

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1004 Once Daily Mometasone Furoate Aqueous Nasal Spray in Seasonal Allergic Rhinitis: An Active and Placebo-Controlled Study Hebert J MD, Nolop KB MD, Lutsky BN PhD, 192-200 Study Group, Quebec, Canada; Kenilworth, NJ

1005 Evaluation of Safety and Efficacy of Dexacort ru, Turbinaire® (DEX) Nasal Spray in Patients with Perennial Allergic Rhinitis Rachelefsky G MD, Adelglass J MD, Corren J MD, Spector S MD, Schanker H MD, Kiely L, Siegel S MD, Los Angeles, CA; Dallas, TX

1006 Comparative CNS Depressant Effects of Cetirizine and Classical Antihistamines in an Experimental Animal Model de Prado M MS, Sherwood J MS, Hey JA PhD, Kenilworth, NJ

1007 Onset of Action, Efficacy and Safety of a Single Dose of 60 mg and 120 mg Fexofenadine HC1 for Ragweed (RW) Allergy Using Controlled Antigen Exposure in an Environmental Exposure Unit (EEU) Day JH MD, Briscoe MP MD, Welsh A BSc, Smith J BScH, Mason J RN MN, Kingston, Ontario, Canada

1008 A Placebo-Controlled Trial of Cetirizine in Seasonal Allergic Rhinitis in Children Aged 6 to 11 Lumry WR MD, Pearlman DS MD, Dallas, TX," Aurora, CO

1009 Efficacy and Safety of Fexofenadine HCI in Fall Seasonal Allergic Rhinitis Tinkelman D MD, Bronsky E MD, Kaiser H MD, Mason J RN MN, Falliers C MD, Denver, CO; Salt Lake City, UT; Minneapolis, MN," Kansas City, MO

1010 Fexofenadine: A New Nonsedating Antihistamine is Effective in the Treatment of Seasonal Allergic Rhinitis Bernstein D MD, Schoenwetter W MD, Nathan R MD, Storms W MD, Mason J RN MN, Cincinnati, OH

1011 Acute and Subchronic Effects of Cetirizine Terfenadine, Diphenhydramine & Placebo on Cognition in the Elderly Gengo F PharmD, Kinkel P MD, Buffalo, NY

1012 Early Nasal Effect of Cetirizine and Loratadine in Allergic Rhinitis Frossard N PhD, Lacronique J MD, Melac M MD, Benabdesselam O MD, Glasser N PhD, Pauli G MD, Strasbourg, Paris, France

1013 Intranasal Doxepin HCI in the Treatment of Allergic Rhinitis Fink J MD, Lawrence I MD, Palo W MS, Podpora J BS, Milwaukee, WI; Lincolnshire, IL

1014 A Comparison of Third Generation Antihistamines with a First Generation Antihistamine in the Treatment of Perennial Allergic Rhinitis Crawford WW MD, Lee PH, Placik IM MD, Klaustermeyer WB MD, Los Angeles, CA

1015 Evaluation of Efficacy and Duration of Action of Levocabastine (LEVO) Nasal Spray Under Nasal Challenge Condition X Spector S MD, Corren J MD, Rachelefsky G MD, Schanker H MD, Siegel S MD, Los Angeles, CA

1016 Ketoconazole Enhances the QTc Interval Prolognation Effects of the Nonsedating Antihistamines Terfenadine and Ebastine in an Experimental Animal Model Hey JA PhD, del Prado M MS, Kreutner W PhD, Egan RW PhD, Kenilworth, NJ

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1017 The Electrocardiographic Effects of Loratadine Syrup in Pediatric Patients Harrison JE MD, Danzig MR PhD, Lorber RR MD, Kenilworth, NJ

1018 Clemastine (CLEM) (0.5 Mg) Partially Inhibits the Early Nasal Allergic Reaction When Given 4 and 6 Hours (Hrs) Before Nasal Challenge with Allergen Baroody FM MD, Chung J BS, DeTineo M RN, Sorrentino J PhD, Winslow CM PhD, Naclerio RM MD, Chicago, IL; Hanover, NJ

1019 Topical Azelastine and Levocabastine Protection on Histamine Nasal Provocation Test Roger A, Simon J, Lucas C, Marti E, Barcelona, Spain

1020 Levocabastine Versus Cetirizine in Children with Perennial Allergic Rhinitis (PAR) Arreguin L MD, Cerino R MD, Meza A MD, Garcia R MD, Mexico City, Mexico

1021 A Multicenter Study of the Taste of the Once-Daily Antihistamine Cetirizine in Children with Perennial Allergic Rhinitis Adelglass JM MD, Dallas, TX

1022 Allergies Are Not a Cause of Chronic Fatigue Syndrome (CFS): IgE Concentrations and Prevalence of Allergic Rhinitis in Atopic, CFS, and Negative Control Populations MacDowell-Cameiro AL, Pandiri P, Foong S, Ali M, Bellanti J, Clauw D, Baraniuk JN, Washington, D.C.

1023 Chronic Nonallergic Rhinitis Complaints Identified in Chronic Fatigue Syndrome (CFS) Gaumond E, Radulovic D, Wethington S, Wilson B, Ciauw D, Baraniuk JN, Washington, DC

1024 Pollinosis in Southern Brazil Vieira F MD, Caxias do Sul, Brazil

1025 Relevant Pollens in the Etiology of Seasonal Allergic Rhinitis in the City of Bahia Blanca (Argentina) and its Surrounding Area Ram6n GD MD, Bronfen S, Villamil CB PhD, Ferrer N Lic, Apphatie S, Barz6n S, Buenos Aires, Argentina

1026 Mold Allergy is a Risk Factor for Persistent Cold-Like Symptoms in Children in Winter Huang SW MD, Kimbrough J PhD, Gainesville, FL