school of studies in neuroscience profile 08

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School of Studies in Neuroscience JIWAJI UNIVERSITY, GWALIOR Madhya Pradesh 474011, India Telefax: +91-751-2442789 [email protected] www.neuroscienceju.com India’s 1 st University Teaching Department of Neuroscience Message There has never been a more exciting time to study the brain – the subject called NEUROSCIENCE. Neuroscience is truly interdisciplinary and rapidly expanding today. We are trying to develop NEUROSCIENTISTS of tomorrow. A career in neuroscience demands training in diversified areas like biology, psychology, anatomy, physiology, pharmacology, toxicology, occupational biology, structural & molecular neurobiology, neurogenesis etc. The M.Sc. Neuroscience teaching programme provides training in most of these areas. Along with theory and practical, students are encouraged to participate in ongoing faculty research as well as national and International training programmes of International Brain Research Organization, National Brain Research Centre and alike. Three of our M.Sc. Students have published research papers based on their project work in journals of reasonably high Impact Factor. More than 75% of our students are working in India and abroad for their Ph.D. theses. Many are placed in R&D laboratories of pharmaceuticals companies. Isn’t it exciting to know all these? If you are looking forward to an exciting and challenging career, come and join us in our venture to prepare brains to understand how the brain makes us understand. Best wishes! Ishan Patro Ph.D, FIAN Coordinator-Head

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Page 1: School of Studies in Neuroscience Profile 08

School of Studies in Neuroscience JIWAJI UNIVERSITY, GWALIOR Madhya Pradesh 474011, India

Telefax: +91-751-2442789 [email protected]

www.neuroscienceju.com

I n d i a ’ s 1 s t U n i v e r s i t y T e a c h i n g D e p a r t m en t o f N e u r o s c i e n c e

Message

There has never been a more exciting time to study the brain – the subject called NEUROSCIENCE. Neuroscience is truly interdisciplinary and rapidly expanding today. We are trying to develop NEUROSCIENTISTS of tomorrow.

A career in neuroscience demands training in diversified areas like biology, psychology, anatomy, physiology, pharmacology, toxicology, occupational biology, structural & molecular neurobiology, neurogenesis etc. The M.Sc. Neuroscience teaching programme provides training in most of these areas.

Along with theory and practical, students are encouraged to participate in ongoing faculty research as well as national and International training programmes of International Brain Research Organization, National Brain Research Centre and alike. Three of our M.Sc. Students have published research papers based on their project work in journals of reasonably high Impact Factor.

More than 75% of our students are working in India and abroad for their Ph.D. theses. Many are placed in R&D laboratories of pharmaceuticals companies.

Isn’t it exciting to know all these? If you are looking forward to an exciting and challenging career,

come and join us in our venture to prepare brains to understand how the brain makes us understand.

Best wishes! Ishan Patro Ph.D, FIAN

Coordinator-Head

Page 2: School of Studies in Neuroscience Profile 08

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School of Studies in Neuroscience* JIWAJI UNIVERSITY, GWALIOR

*1st University Teaching Department of Neuroscience in the Country

The School of Studies in Neuroscience offers a platform for research and teaching

towards understanding the structure and function of the brain. This is the first and only Post-Graduate Department in Indian Universities extending interdisciplinary and inter-Institutional training to students leading to the award of M.Sc. Neuroscience degree.

Generous financial support from the Department of Biotechnology, Department of Science & Technology, Council of Scientific and Industrial Research, Indian Council of Medical Research, University Grants Commission and other agencies during past few years and strong academic backup and support from distinguished neuroscientists of national and international stature have allowed us to develop a research centre which one can boast of. We have successfully executed several major research projects, organized training workshops for research scientists and University and college teachers, symposia and conferences of National and International level. The School is well equipped with modern instrumentation as well as a good library. Our neuroscientists have been trained in leading Institutes in India and abroad. The students who obtained M.Sc. and Ph.D. from this Department are now working in established Institutes in the country and abroad.

The M.Sc. Neuroscience (supported by the Dept. of Biotechnology, Govt. of India) teaching programme takes care of the basic disciplines such as anatomy, physiology, biochemistry, cell and molecular biology, pharmacology, etc. which provide a broad base during the first semester. This is followed by gradually specialized areas of neuroscience like neurochemistry, molecular neurobiology, genetics, neuroimmunology, development of brain, degeneration and regeneration of nervous system, systems neuroscience, learning, memory and cognition, clinical neurochemistry, tools, techniques and methods in neurobiology research.

In order to inculcate research skills in our students, in addition to their training at our research laboratory they get an exposure by way of project work/ training for up to 6 months in an established neuroscience laboratory.

We also make special efforts to promote an excellent general education that would provide the basis for careers in other areas such as teaching, commerce, and administration and management.

For more details please visit: www.jiwaji.edu and www.neuroscienceju.com Objective of the Course

The M.Sc. programme has been designed to prepare students for: (1) Neuroscience research oriented positions in academia and industry, (2) Carriers at the interface of the bench and bedside in the academic

neuroscience or (3) Even in the application oriented biomedical industry.

Scope for Placement

M.Sc. Neuroscience programme has been designed to train students for neuroscience research oriented positions in Universities/Institutes/R&D Units of Pharmaceutical Companies engaged in production of neuropharmacological products and diagnostics, in India and abroad. Number of Seats Available: 10 + NRI, No payment seats. Studentship: Ten students shall be entitled for a studentship of Rs.1,200 pm.

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Teaching Methods The course is completed in a truly interdisciplinary and inter-Institutional mode. A

variety of teaching methods are adopted including interactive lectures and seminars, group work, practical classes, computer based exercises as well as external visits to hospitals, Laboratories, Institutes, etc. Course Structure

It is a 2 years (4 Semesters) teaching programme. The students with a M.Sc. degree in Neuroscience would have acquired the basic knowledge in major disciplines of the subject such as neuroanatomy, neurophysiology, neurochemistry, molecular neurobiology, neurogenetics and the working of motor, sensory and regulatory systems, development and regeneration of the brain as well as aspects of biotechnology such as cell biology, biochemistry, molecular biology, immunology and tools of the trade. They would also acquire practical training in the above aspects as well as in research methodology and computational skills. M.Sc. Neuroscience: Theory and Practical Courses* Semester-I NS/101- Cell Biology and Neuron Organization NS/102- Biochemistry NS/103- Genetics and Molecular Biology NS/104- Laboratory Tools and Techniques NS/105- Laboratory Course-I: Cell Biology NS/106- Laboratory Course-II: Genetics, Biochemistry and Molecular Biology

Semester-III NS/301- Neurochemistry NS/302- Systems Neuroscience-I: Sensory and Motor Systems NS/303- Systems Neuroscience-II: Regulatory System NS/304- Behaviour and Cognitive Neuroscience NS/305- Laboratory Course-V: Neuropathology NS/306- Laboratory Course-VI: Behavior biology

Semester-II NS/201-Neuroanatomy NS/202-Immunology NS/203-Developmental Neurobiology NS/204-Cellular Neurophysiology and Biophysics NS/205- Laboratory Course-III: Neuroanatomy NS/206- Laboratory Course-IV: Neurophysiology

Semester-IV NS/401- Clinical Neurochemistry and Neuropathology NS/402- Nanotechnology and Bioinformatics for Neuroscience NS/403- Laboratory course-VII: Research Methods, Biostatistics and Computer Applications NS/404- Dissertation NS/405- Viva-voce related to the Dissertation

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Faculty

The faculty consists of well experienced teachers and scientists from Jiwaji University and premier Universities/ Institutes such as All India Institute of Medical Sciences, Jawaharlal Nehru University, Banaras Hindu University, University of Hyderabad, Jamia Hamdard, Industrial Toxicology Research Centre, G.R. Medical College, ITM Universe and others. Adjunct Faculty Name Specialization 1 Dr. I.K. Patro Neurobiology 2 Dr. O.P. Agarwal Biochemistry 3 Dr. Y.K. Jaiswal Molecular Biology 4 Dr. P.K. Tiwari Human Genomics 5 Dr. S.K. Gupta Instrumentation/ Statistics Visiting Faculty Name University/ Institute Specialization 1 Prof. Rameshwar

Singh School of Life Sciences, Jawaharlal Nehru University, New Delhi

Neurophysiology

2 Prof. Shashi Wadhwa Dept. of Anatomy, All India Institute of Medical Sciences , New Delhi

Neuroanatomy

3 Prof. S.K. Jain Dept. of Biotechnology, Jamia Hamdard, New Delhi

Molecular Biology

4 Prof. T.S. Roy Dept. of Anatomy, All India Institute of Medical Sciences, New Delhi

Neuroanatomy

5 Prof. S.B. Ray, Dept. of Anatomy, All India Institute of Medical Sciences, New Delhi

Neuroanatomy

6 Dr. Suman Jain Dept. of Physiology, All India Institute of Medical Sciences, New Delhi

Neurophysiology

7 Prof. M.K. Thakur Centre for Advanced Study in Zoology, Banaras Hindu University, Varanasi

Molecular Neurobiology

8 Dr. Shukla Prasad Centre for Advanced Study in Zoology, Banaras Hindu Univ., Varanasi

Biochemistry, Molecular Biology

9 Dr. S. K. Trigun Centre for Advanced Study in Zoology, Banaras Hindu Univ., Varanasi

Biochemistry, Molecular Biology

10 Dr. R. K. Mishra Centre for Advanced Study in Zoology, Banaras Hindu Univ., Varanasi

Bioinfornatics

11 Dr. V.K. Khanna Industrial Toxicology Research Centre, Lucknow

Neurochemistry

12 Prof. Neelima Singh G.R. Medical College, Gwalior Biochemistry 13 Dr. Nisha Patro IASCA, ITM Universe, Gwalior Developmental

Neurobiology, Immunology

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Research Staff* 1 Ms. Radha Gupta, DBT- Research associate 2 Mrs. Sarika Kushwah, JU-JRF 3 Mr. Kapil Saxena, UGC-NET-SRF 4 Ms. Meghna Shrivastav, ICMR-SRF 5 Ms. Surya Tripathy, JU-JRF 6 Mr. Amit Awasti, DBT-JRF 7 Mr. Kamendra, DBT-BET-JRF 8 Ms. Arpita Sharma, DBT-JRF 9 Ms. Shashank Tiwari, ICMR- Research Asst. * Along with research they also participate in teaching Extension Lectures by Eminent Neuroscientists from India and Abroad Prof. P.N. Tandon, President, National Brain research Centre, Manesar. Prof. M. Gourie Devi, Sr. Consultant Neurologist, Sir Ganga Ram Hospital, New Delhi & Hon. Advisor in Neurological Research, ICMR, New Delhi. Prof. Mahdi Hasan, Emeritus Professor, KG’s Medical University, Lucknow. Prof. K. Subba Rao, School of Life Sciences, Hyderabad university, Hyderabad. Prof. P.K. Seth, CEO, Biotechnology Park, Lucknow. Prof. Vijayalaxmi Ravindranath, Director, National Brain Research Centre, Manesar. Prof. Y.K. Gupta, Head, Dept. of Pharmacology, All India Institute of Medical Sciences (AIIMS), New Delhi. Prof. V.K. Bhasin, Dept. of Zoology, University of Delhi, Delhi. Dr. Pamela Baker and Dr. D.L. Baker, College of Lewiston, Maine, USA Dr. Srinivas N. Pentyala, School of Medicine, State University of New York, NY, USA. Dr. Stan Terrace, Rainishaw, UK. National Symposium on Neurobiology (October 23, 2007)

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Students’ Achievements

Our students have been very actively participating in various scientific activities, training programmes and conferences, etc. Some of the important events attended during 2006-2008 are as follows: Students’ Participation in Academic Events: Abroad

“International Brain Research Organization & International Society for Neurochemistry School in Neuroscience” National University of Singapore. 25th June- 16th July, 2006

“6th IBRO- Associate School of Neuroscience” Venue: Tarbiat Modarres University (TMU), Tehran, Iran. Organized by: International Brain Research Organization (IBRO) and TMU, Iran. 26th -30th Aug 2006

“1st Neuroscience Orientation Summer Program” Venue: SB Medical University and TMU, Tehran, Iran. Organized by: Iranian Society of Physio. and Pharma. and IBRO. 2nd -21st Sept 2006

“Biennial Meeting of Asia Pacific Society for Neurochemistry (Conference)”, Scientific Exhibition and Conference Center, Singapore. 17th July, 2006

“1st UAE- IBRO Neuroscience School- Fundamentals of Basic and Clinical Neurosciences” UAE University, Al Ain, UAE. Organized by: UAE University Neuroscience Group and IBRO. 24th - 31st Jan 2007

India

“Brain Awareness Day.” School of Life Sciences, Jawaharlal Nehru University (JNU), New Delhi, Organized by: JNU & NBRC, Manesar, Haryana, India. 03rd April 2006

“National Symposium on Neural Plasticity and Repair” and “Workshop on Evaluation of Plastisity in Pain” Department of Anatomy & Physiology, All India Institute of Medical Sciences (AIIMS), Ansari Nagar, New Delhi- 11002 & Indian Society of Pain Research and Therapy18th – 19th October 2006

“Workshop on Good Laboratory Practices (GLP) for Academia” AIIMS, New Delhi. Organized by: Dept. of Sci. & Tech., Government of India. 24th & 25th Nov 2006

“III International NBRC Conference” National Brain Research Centre, Manesar, India. 13th -15th Dec 2006

DSI- GENTECH Workshop “Building an Integrated Physiological Monitoring System: A Discussion and Demonstration of DSI Product and their Application” Taj Hotel, New Delhi 12th October 2006

“Workshop on Bioinformatics and Biomathematics” at SOMAS, Jiwaji University, Gwalior. 14th -16th January 2006

24th annual conference of Indian academy of Neuroscience: “International update on basics and clinical neuroscience advances” Industrial toxicology research centre, Lucknow, 17th- 20th December 2006

26th Annual Meeting of Toxicology (STOX) India “International Conference on Toxicology, Toxicogenomics and Occupational Health (ICTTOH), at Jiwaji University, Gwalior. 9th -11th October 2006

How to Write a Scientific/ Medical Paper? Jointly organized by Cancer Hospital and Research Unit, Gwalior and Gajra Raja Medical College, Gwalior. 24th September 06.

“Centenary Commemoration of Alzheimer’s Disease & 12th Annual Conference of Alzheimer’s and Related Disorders Society of India” New Delhi. 9th -11th November 2006

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Workshop on “Neurochemical Techniques for the Neuroscientists”, Indian Institute of Chemical Biology funded by International society for Neurochemistry and International Brain Research Organization. 29th December 2006 -7th January 2007

Annual Conference of Society for Neurochemistry, India (SNCI) at Indian Institute of Chemical Biology, Kolkata. 8th- 9th January 2007

One week Hands-on Training at the Bhopal Memorial Hospital and Research Centre, Bhopal. 12th -19th February 2007

International Symposium on Advances in Neuroscience and Silver Jubilee Conference of Indian Academy of Neuroscience at Banaras Hindu University, Varanasi. 22nd -25th November 2007.

National Seminar on “Nanotechnology and its Applications” Jiwaji University, Gwalior. 30th March 2008

Poster/ Papers Presented in Conferences, etc. (2006-2008): By M. Sc. Students:

1. Ranjan Kumar. Gap Junctions in Brain: Functions in Health and Disease (Oral Presentation). 5th IBRO-ISN School at National University of Singapore (20th -30th June 2006)

2. Jitendra K. Sinha. Age Changes in Human Abducens Nerve: A morphometric study. (Poster). 6th IBRO Associate School, Tehran, Iran (2nd – 21st September 2006)

3. Ranjan Kumar. Histochemical and Immunohistochemical Study of Cerebral Cortex in Developing Fetal Brain (Oral Presentation). 4th FAONS Congress at Chinese University of Hong Kong, Shatin, Hong Kong. (2nd -4th December, 2006)

4. Jitendra K. Sinha. Age Changes in Adult Human Abducens Nerve (Poster). III International NBRC Conference, NBRC, Manesar, India (December, 2006)

5. Jitendra K. Sinha. A morphometric study of human 6th cranial nerve (Oral Presentation) 1st UAE-IBRO Neuroscience School, Al Ain, UAE (24th -31st January 2007)

Students with Padmavibhushan Prof. P.N. Tandon President, National Brain Research Centre, Manesar. President, IAN

With Prof. M. Ito RIKEN Institute, Japan. President, FAONS

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6. Kamendra Kumar, Effect of Postnatal Exposure to Deltamethrin (DLT) on

Spontaneous Motor Activity and Motor Coordination in Rat. (Poster). National Symposium on Glial Neurobiology held at Jiwaji University, Gwalior. (23rd October 2007)

7. Shashank Tiwari. FK506 Helps Motor Co-ordination Recovery Following Sciatic Nerve Transection in the Young but not in Senile Rats” (Poster). International Symposium on Advances in Neurosciences and Silver Jubilee Conference of Indian Academy of Neurosciences held at Banaras Hindu University, Varanasi. (22nd -25th November, 2007).

8. Kamendra Kumar, Effect of post-natal exposure to Deltamethrin on Locomotor Activity and Motor Coordination in Rats. (Poster). International Symposium on Advances in Neurosciences and Silver Jubilee Conference of Indian Academy of Neurosciences held at Banaras Hindu University, Varanasi. (22nd-25th November, 2007)

By Research Scholars:

9. Kapil Saxena “Studies on the Influence of FK506 on Microglial Proliferation and activation in the spinal cord following sciatic nerve injury” (Poster). XXII Annual Conference of Indian Academy of Neurosciences at Hyderabad Central University, Hyderabad (6th – 8th May 2004)

10. Kapil Saxena. FK506 Suppresses Microglial Activation in the Spinal Cord following Sciatic Nerve Injury” (Poster). Annual conference of Society for Neurochemistry, India (SNCI), Indian Institute of Chemical Biology, Kolkata, (8th - 9th January 2007)

11. Meghna Shrivastava, Impact of Altered S-100 Protein Expression on Purkinje Neuron Dendritogenesis and Spontaneous Motor Activity in Rat Pups Exposed to Deltamethrin (Poster). International Symposium on Advances in Neuroscience and Silver Jubilee Conference of Indian Academy of Neuroscience at Banaras Hindu University, Varanasi (22nd -25th November 2007).

12. Meghna Shrivastava, Age Related Changes in Pain Sensitivity Differ in Male and Female Rats (Poster). International Update on Basic and Clinical Neuroscience Advances and 24th Annual Conference of Indian Academy of Neuroscience at ITRC, Lucknow. (17th-20th Dec. 2006).

13. Kapil Saxena, FK506 protects neurons following peripheral nerve injury via immunosuppression (Oral Presentation). International Update on Basic and Clinical Neuroscience Advances and 24th Annual Conference of Indian Academy of Neuroscience at ITRC, Lucknow. (17th-20th Dec. 2006).

Research publications of M.Sc. Students based on their Project Work Gaur, Pankaj, Thakur, B.K., Sharma, P.K., Oka, T. and Thakur, M.K. (2005) Expression of perchloric acid soluble 14kDa protein in mouse brain. Annal of Neurosciences, volume12, 12-15. Kumari, Amrita, Sen, Sreetama and Mohanakumar, KP (2007) Atropine, a muscarinic cholinergic receptor antagonist increases serotonin, but not dopamine levels in discrete brain regions of mice Neuroscience Letters 423(2):100-3 (I.F. about 2.00). Patro, I., Saxena, K., Tiwari, S and Patro, N. (2008) FK506 helps motor Co-ordination recovery following sciatic nerve transection in the young but not in senile rats. International Journal of Neuroprotection and Neuroregeneration (In Press).

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M.Sc. Students Attended IBRO and FAONS Conferences Abroad Name of Student Conference/ school Duration Mr. Ranjan Sharma • IBRO-ISN Neuroscience School, Singapore.

• 7th Biennial meeting of the Asian Pacific Society for Neurochemistry, Singapore.

• 4th FAONS Congress at Chinese University of Hong Kong, Shatin, Hong Kong

• 20th-30thJune 2006 • 2-5 July 2006

• 2nd -4th December, 2006

Mr. Jitendra Sinha • 6th IBRO-Associate School of

Neurosciences, Tehran. • Neuroscience Orientation Programme,

Tehran. • UAE IBRO Neuroscience School.

• 26th-30th Aug, 2006

• 2nd-21st Sept., 2006

• 24th-31st Jan., 2007

Mr. Neeraj Soni • Advanced School of IBRO, RIKEN, Japan • 26th Feb-9th March,‘07

Activities at the School

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Training & Placement

The first 5 batches (48 students) passed out in July 2003, July 2004 and July 2005, respectively. Of these 48 students, 30 have been able to get placement in leading Neuroscience Laboratories of the country through the selection procedures of the respective Institutes they are in. Two students have cleared the CSIR-UGC NET, one in BET and most have qualified the GATE with very good percentiles. Many of the students have appeared in the NET examination the result of which is awaited. The placement details are as follows: Placement

Abroad

• Cambridge University, UK • CCHD Ph.D, Vienna Medical University, Austria. • MCBO, Innsbruck Medical University, Innsbruck, Austria

India

• Department of Zoology, MLS University, Udaipur • Departments of Anatomy and Physiology. All India Institute of Medical

Sciences, New Delhi • Dept. of Zoology, Banaras Hindu University, Varanasi • Division of Pharmacology, Central Drug Research Institute, Lucknow • National Centre for Biological Sciences, TIFR, Bangalore • National Institute of Mental Health and Neuro Sciences, Bangalore • Natonal Brain Research Centre, Manesar, Gurgaon • School of Life Sciences, Jawaharlal Nehru University, New Delhi • School of Studies in Neurosciences, Jiwaji University, Gwalior. • Dr. Reddy’s Lab, Hyderabad • HariHar Biotech., Agra • Reliance Clinical, Mumbai • Suven Life Sciences, Hyderabad • Tata Consultancy Services, Noida

Training of students at other Institutes

• All India Institute of Medical Sciences (AIIMS), New Delhi • Banaras Hindu University (BHU), Varanasi • Central Drug Research Institute (CDRI), Lucknow • Centre for Cellular and Molecular Biology (CCMB), Hyderabad • Defence Institute of Physiology and Applied Sciences (DIPAS), New Delhi • Defence Research and Development Establishment (DRDE), Gwalior • GR Medical College, Gwalior • Indian Army • Indian Institute of Chemical Biology (IICB), Kolkata • Indian Institute of Sciences (IISc), Bangalore • Indian Institute of Technology (IIT), Kanpur • Industrial Toxicology Research Centre (ITRC), Lucknow • Institute of Genomics and Integrated Biology (IGIB), Delhi • Jawaharlal Nehru University (JNU), New Delhi • KG’s Medical University, Lucknow • MLS University, Udaipur • National Centre for Biological Sciences (NCBS), TIFR, Bangalore • National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore • SN Pradhan Centre for Neuroscience, Univ. of Calcutta, Kolkata • University of Hyderabad, Hyderabad

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Available Facilities at the School Books and Journals We have more than 650 books available on Neuroscience and allied areas. Equipments

Leica Fluorescence Microscope Leica Image Analysis System Leica Stereozoom microscope Leica Table Top Cryostat Leica Automatic Vibratome Leica Microtome Eppendorf Thermalcycler (PCR) Eppendorf Minispin plus Heraeus Ultra Low Temp. Deep Freezer Columbus Animal activity monitor Columbus Grip strength meter Columbus Rota-rod treadmills Columbus Analgesia tail flick instrument Biopac Electrophysiological setup

Lab Standard stereotaxic apparatus Stoelting Motorized Nano-injector Shimadzu UV-Vis Spectrophotometer Olympus Drawing Microscope Olympus Research Microscope INCO Stereotaxic Apparatus Weswox Rotary Microtome Spencer Sliding Microtome Biotech Electrophoresis set-up Laboratory microscopes Systronics digital Spectrophotometer Laminar flow bench Incubator cum Orbital Shaker Other minor equipments

Facilities at the School

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Research Activities Ph.D. Programme The Centre intends to educate future scientists who will become leading researchers and educators in the brain sciences. Key Areas of Study • Involvement of glia in brain development,

aging and injury

• Cellular and molecular basis of brain aging • Neurotoxicology: Developmental

Neurotoxicology • Adult Neurogenesis (Neural stem cell research) Research Projects

During 1989-2007 we have completed 08 research projects and 03 are in hand on aspects of brain research like neurotoxicology of commonly used household and agriculturally important chemicals, stress and brain response, development of brain areas, possibility of retardation of aging changes in brain, drugs for the aging brain, behaviour and color change in animals and cell death in brain at old age. We have been supported by the Department of Biotechnology Department of Science & Technology, Council of Scientific and Industrial Research and Defense Research and Development Establishment. The following is a detailed information on our research projects.

S. No.

Funding Agency

Principal Investigators

Title in Rs. Lacs.

Completed

1. DST Dr. I.K. Patro Influence of certain geroprotectors on neuronal ageing in environ-mentally stressed and ageing albino rats (1987-1990)

2.3

2. DST Dr. I.K. Patro Experimental manipulation of longevity, lipofuscin formation and neuron loss in mouse brain (1992-1996)

12.09

3. CSIR Prof. S.P. Sharma

Dr. I.K. Patro

Studies on antioxidant nutritional influences on autoxidation, lipofuscin accumulation and ageing of albino rats/mice (1987-1990)

1.5

4. DRDE Dr. I.K. Patro

Dr. S.C. Pant

Dr. S. DasGupta

Influence of organophosphorus compounds on developing nervous system of rats: Histopathology and Histochemical localization of AChE (1990)

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5. DST Dr. Nisha Patro Effects of deltamethrin on Development of cerebellum and locomotory behaviour in rat (1994-1997)

04.12

6. DBT Dr. I.K. Patro Role of Microglial activation on neuronal apoptosis (2000- 2004)

28.14

7. DST Dr. I.K. Patro Studies on immunophilin ligand as novel modulators glial activity and mediators of neuroprotection (2002-2006)

17.86

8. DST Dr. Nisha Patro Role of glia in pathogenesis of neurodevelopmental disorders (2003-2006)

18

On-going

9. DBT Dr. I.K. Patro/

Dr. Nisha Patro

Role of microglia in adult neurogenesis (2006-2009)

62.73

10. ICMR Dr. I.K. Patro/

Dr. Nisha Patro/

Dr. Y. K. Jaiswal

Aging of microglia (2007-2010) 31.6

11. DBT Dr. I.K. Patro/ Prof. S.K. Shankar (NIMHANS)/ Dr. Anita Mahadevan (NIMHANS)

Phynotypic alterations in astroglia and microglia in the brain- in response to tuberculous pathology in association with HIV/AIDS (2008-2010)

20.81

12. DBT Dr. I.K. Patro

Coordinator

DBT-HRD M.Sc. Neuroscience programme 2004- Continuing

79.68

Training Workshops Organized

1. Sixth Neuroscience Society of India Workshop on Techniques in Neuroscience, December 8-20, 1997

2. Workshop on Morphometric Evaluation of Brain for Neurotoxicological Studies, December 3-5, 1999

3. DBT Short-term Training Course on Cloning and Expression of Animal Genes, July 15 - August 4, 1997

4. National Training Workshop on State of the Art Techniques in Cell and Molecular Biology, August, 7- 16, 1997

5. Planning and presentation of Research Proposals, August 10, 2001

Conferences and Symposia Organized in Neuroscience:

1. National Symposium on Biology of Ageing, October 29-31, 1993 2. National Conference on Gerontology & Symposium on Molecular Markers of

Ageing, April 7-9, 1997 3. National Symposium on Frontiers of Neuroscience, December 8, 1997 4. 'Neuroscience 2000 and Beyond': 17th Annual Conference of Indian

Academy of Neurosciences, Annual Meeting of Neuroscience Society of India, National Symposium on Cellular and Molecular Basis of Brain Function, December 6-8, 1999

5. Neuroscience: From Basics to Clinics, 22nd Annual Conference of Indian Academy of Neurosciences, 2005

6. National Symposium on Glial Neurobiology, October 23, 2007

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Training Obtained in India and Abroad

Neuroscientists of the Department have visited some leading international Centres like the MRC Neurochemical Pathology Unit, Newcastle upon Tyne, UK; Department of Molecular Biology, North-Western University, Evanston, Illinois, USA; Department of Physiology, University of Queensland, Brisbane, Australia; Department of Physiology, University of Singapore, Singapore. The recent one at the University of Cologne, Germany. We actively collaborate with some of the leading Institutes in the Country in executing our activities. Collaborative exchange program with a German Institute was supported by Deutsche Forschungsgemeinschaft (DFG) and Indian National Science Academy (INSA). We are now strengthening this relationship.

Our Faculty and Post-doctoral Fellows have participated in the Overseas Collaborative research at the MRC Neurochemical Pathology Unit at Newcastle upon Tyne.

We now have research collaboration with Scientists at NIMHANS, Bangalore; AIIMS, New Delhi and CDRI, Lucknow.

Students of Earlier Batches

Contact Person

Dr. Ishan Patro, Coordinator-Head, School of Studies in Neuroscience, Jiwaji University, Gwalior.

Telefax: 0751-2442789

E-mail: [email protected]