scevola d- 2000 tables
TRANSCRIPT
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Tables
Table 1. Role of Lipoproteinlipase in Various Tissues
Tissue Role
Muscle (cardiac, skeletal) Energy provision
White adipose tissue Triglyceride storage
Brown adipose tissue Thermogenesis
Lactating breast Milk triglyceride synthesis
Lung ur!actant synthesis"
Brain #hospholipid and glycolipid synthesis"
$nknown %drenal, kidney, spleen, !etal liver
"#utative&
Table 2. Changes in Body Shape in HIV-infeted !atients Reei"ing !rotease
Inhibitor Therapy
#o hange $ild $oderate Se"ere
Body shape ' *+ - ''
Loss o! subcutaneous !at + ' + '-
.ri/ belly 0 - ++ '
Bu!!alo hump 1- '-
Table %. &ifferenes Bet'een (asting Syndro)e and Lipodystrophy Syndro)e
syndro)e
(asting Lipodystrophy
Body weight 2ecrease 3ncrease or decrease
Body !at 2ecrease, all areas#eripheral decrease,
central increase
Lean body mass 2ecrease $nchanged
Total cholesterol 2ecrease 3ncrease
4L2L cholesterol 2ecrease 3ncrease
L2L cholesterol 2ecrease 3ncrease
52L cholesterol 2ecrease 2ecrease
Triglycerides 3ncrease 3ncrease2iabetes6insulin resistance 7o 8es
.oronary artery disease 7o 8es
4L2L, very low9density lipoprotein: L2L, low9density lipoprotein: 52L, high9density lipoprotein&
Table *. &iagnosti Criteria for HIV Lipodystrophy Syndro)e or $etaboli
Syndro)e +
$ain riteria
534 in!ection#3 therapy
Loss o! peripheral !at tissue3ncreased central !at tissue
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(abdominal girth)
$inor riteria
4isible subcutaneous veinsLoss o! temple, nasolabial, and
cheek !at padsBu!!alo hump or bull neck
Breast hypertrophy
Enlarged supraclavicular !atpadsBilateral symmetric lipomatosis
(enlarged a/illary !at pads)2ecreased thigh si;e
5yperlipidemia (cholesterol,triglycerides)
,dunti"e riteria
2iabetes
#eripheral insulin resistance5yperinsulinism
5yperuricemiaLow serum testosterone
3ncreased . peptide3ncreased !ree !atty acids
.oronary artery disease,ischemic heart disease
5ypertension
Table . The Harris-Benedit /0uation (ith ,dunti"e Calories for Various
Conditions
urgical operation 0
Trauma '- 9 '0
.omplicated trauma +- 9 0-#eritonitis '0 9 +-
Minor in!ection 0 9 +-
evere in!ection *- 9 )
7%32s (indomethacin, ibupro!en, aspirin) (=educes #? synthesis)
#E#, phosphoenolpyruvate: c%M#, cyclic adenosine monophosphate: T7>, tumor necrosis !actor: 7%32s,nonsteroidal anti9in!lammatory drugs: #?, prostaglandin: L#, lipopolysaccharide: 3L9', interleukin9'&
Referenes
'& Torun B,4iteri >E& #rotein9energy malnutrition& 3n@ hils ME, 8oung 4=, eds& Modern 7utrition in 5ealth and 2isease& thed& #hiladelphia@ Lea A >ebiger: '11@*
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rancisco %, et al& The magnitude o! body cell mass depletion determines the timing o! death !romwasting in %32& %m .lin 7utr& '1:0-@***9**&
'%, et al& .orrelation between total body potassium and total body nitrogen in patients withacDuired immunode!iciency syndrome& .lin =es& '':@rancisco& %bstract ThB+-&
'& .hlebowski =T, ?rosvenor MB, Bernhard 75, et al& 7utritional status, gastrointestinal dys!unction, and survival in patientswith %32& %m ?astroenterol& '1:1*@'+119'+&
+-& ?ray ?E, ?ray LF& %nthropometric measurements and their interpretations@ principles, practice and problems& %m 2iet%ssoc& '1-:@0*90&
+'& Blackburn ?., Bistrian B=, Maini B, et al& 7utritional and metabolic assessment o! the hospital patient& #E7& ':'@''9++&
++& 2ouglas =?, haw 5>& Metabolic response to sepsis and trauma& Br urg& '1:la: pp& +--9+-0&+1& Brennan M>& $ncomplicated starvation versus cancer cache/ia& .ancer =es& ':@+09+eingold F=& Metabolic disturbances and wasting in the acDuired immunode!iciency syndrome& 7 Engl Med&'+:0@+9&
-& Wol!e ==, haw 5, 2urkot M& E!!ect o! sepsis on 4L2L kinetics@ responses in basal state and during glucose in!usion& %m #hysiol& '10:+*1@E+9E*-&
'& >eingold F=, 2oerrler W, 2inarello .%, et al& timulation o! lipolysis in cultured !at cells by tumor necrosis !actor,interleukin9', and the inter!erons is blocked by inhibition o! prostaglandin synthesis& Endocrinology& '+:'-@'-9'eingold F=, %di , taprans 3, et al& 2iet a!!ects the mechanism by which T7> stimulates hepatic triglyceride production&AmJ Physiol.'-:+0@E'9E'1*&
& ?run!eld .& Mechanisms o! wasting in in!ection and cancer@ an approach to cache/ia in %32& 3n@ Fotler 2#, ed&?astrointestinal and 7utritional Mani!estations o! %32& 7ew 8ork@ =aven #ress: ''@+-9++&
*& Farmali =%, .hao .., Basu %, Modak M& E!!ect o! n9 and n9< !atty acids on mammary 59ras e/pression and #?E+ levels in2MB%9treated rats& %nticancer =es& '1:@''
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*+& Nu N, 2e #ergola ?, Borntorp #& The e!!ects o! androgens on the regulation o! lipolysis in adipose precursor cells&Endocrinology& '-:'+01&
0-& 5engel =L, Watts 7B, Lenno/ L& Benign symmetric lipomatosis associated with protease inhibitors& Lancet& ':0-@'0E, ilver %, Morley E& The e!!ect o! recombinant human growth hormone on malnourished older individuals& %m ?eriatr oc& '':@+09+*-&
+& Fardinal .?, Loprin;i .L, chaid 2, et al& % controlled trial o! cyproheptadine in cancer patients with anore/ia and6or
cache/ia& .ancer& '-:
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0& 4on =oenn 5& Management o! 5349related body weight loss& 2rugs& '*:*(0)@*91&ioravanti M, et al& .ircadian secretory pattern o! growth hormone, insulin9like growth !actor type
3, cortisol, adrenocorticotropic hormone, thyroid9stimulating hormone, and prolactin during 534 in!ection& %32 =es 5um=etroviruses& ':'*@'+*9'+*&& cevola 2, Bottari ?, Cberto L, et al& Megestrol acetate (M%) and growth hormone (r5?5) as combined therapy !or %32
cache/ia& 3n@ #rogram and abstracts o! the *th .ongress o! European %ssociation !or #alliative .are: 2ecember ebruary *, ': .hicago& %bstractebruary *, ': .hicago& %bstract