ruby ($1,000+) sponsor€¦ · millenium park chicago, illinois, usa table of contents presidential...

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Ruby ($1,000+)

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APSA gratefully acknowledges the following organizations for their sponsorship of the 11th Annual Meeting. Sponsors help make the APSA Annual Meeting possible through financial contributions, sponsorship of speakers, and support of mentorship activities.

Funding for the APSA Annual Meeting (2009-2015) is made possible (in part) by 2R13CA136301-06A1 from the National Cancer Institute. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

Gold ($10,000+) Silver ($5,000+)

11th APSA Annual Meeting April 24-26, 2015, Chicago, IL

Sponsor

11th Annual American Physician Scientists Association(APSA) Conference

In association with:the American Society for Clinical Investigation (ASCI) and

the Association of American Physicians (AAP)

April 24-26, 2015The Fairmont Hotel

Millenium ParkChicago, Illinois, USA

Table of ContentsPresidential Update 3

Annual Meeting Committee Welcome 4

Annual Meeting Gratitude 5

Awards 7

Thursday, April 24 and Friday, April 25 Schedule 9

Saturday, April 26 Schedule 11

Sunday, April 27 Schedule 13 Keynote Speaker Biographies 14

Panelist Biographies 17 Interest Group Mentors 23

APSA Announcements 25

Map of the Fairmont Hotel 26

April 24-26, 2015, Chicago, IL www.physicianscientists.org2

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APSA 2015 Presidential UpdateDear APSA members, colleagues, and friends, Welcome to APSA’s 11th Annual Meeting! We are thrilled that you are joining us for what will surely be an exciting and engaging meeting, filled with great speakers, informative panels, and plentiful networking and social opportunities. This meeting is a reflection of the prominent role that young physician-scientists play in medicine and science. The Annual Meeting is also a reflection of the hard work and dedication that APSA leaders have put in over the last year to provide benefits for our members, advance the training of physician-scientists, and plan for this meeting. In this letter, I will outline just a few of the accomplishments of each of our committees. Our Events Committee, led by Dan DelloStritto (who also serves as president-elect), has put in tireless hours in planning this meeting. The committee recruited high profile speakers, brought in dozens of established physician-scientists to serve as mentors and panelists, and helped provide over thirty travel awards. They have attended to every last detail to ensure that this meeting is productive and goes without a hitch. The committee also helped put on five Regional Meetings this past fall, which included one on the West Coast for the first time since 2007. In aggregate, these Regional Meetings attracted over 600 attendees! A goal of APSA has always been to keep our membership dues low. To help support our operations, our Fundraising Committee (led by Hsin-Pin Lin) has helped to fundraise and secure over $100,000 in grants from companies, non-profit organizations, specialty societies, and the NIH. I want to also take this opportunity to thank our many sponsors (listed on page 1 of this booklet). The generous contributions reflect our sponsors’ belief in the importance of physician-scientists. The core of APSA has always been its members. The membership committee, under Peter Mittwede, has done tremendous work over the past year in improving and increasing the benefits we provide. Over the past year, we held online interactive sessions with mentors including Francis Collins, David Ginsburg, and Mukesh Jain, among many others. We initiated a Local Chapters Initiative that helped APSA spread at local medical schools and provided lunch grants to many of these local chapters. We also started a mentorship program, pairing up over 30 undergraduates with current MD/PhD students. Our Partnerships Committee under Josh Cohen and Stephanie Jackson has been engaging many specialty society partners to provide additional benefits to our members. These include establishing travel awards to our Annual Meeting and travel awards to the specialty society meetings, recruiting mentors for our Interest Group breakfast on Sunday morning, and providing four of the keynote speakers for this meeting. New specialty society partners this year include the American Gastroenterological Association (AGA), American College of Rheumatology (ACR), and the Student National Medical Association (SNMA). A mission of APSA has always been to advocate for its members and on behalf of the physician-scientist community as a whole. Under Jennifer Kwan, the Policy Committee has engaged in a number of initiatives toward this cause. The committee has conducted a large national survey of MD/PhD students to understand the motivations for students to pursue this track and the reasons for attrition along the physician-scientist pipeline. A manuscript outlining the results of this survey is in preparation for submission. The committee also partnered with the Association for Clinical and Translational Science (ACTS) in advocating on Capitol Hill on behalf of physician-scientists. This Annual Meeting will also feature a Policy Panel that will feature Dr. Francis Collins as a panelist. Our Public Relations committee, led by Stephanie Brosius, has done wonderful work this year in a variety of areas. Our social media presence has grown tremendously on Facebook and Twitter. The committee has retooled our marketing campaign for reaching out to sponsors, which has helped greatly in our fundraising efforts. The committee also used their creativity and professional-level design skills to put together our newsletters, as well as this Annual Meeting program. Alex Adami, chair of the technology committee, is the backbone of this organization. He has valiantly managed all of the organization’s technology needs over the last few years, making sure our website runs smoothly, maintaining our membership database, and managing the A/V at the Annual Meeting, and doing many of the “behind the scenes” tasks that keep this organization running. He has taken on a Herculean task, one that is often under-recognized. I also want to thank Aaron Adair and the Sherwood Group for their work in managing our organization. The team at Sherwood has worked tirelessly over the last few years to help grow our organization, and I can confidently say that we would not be where we are today without them. They have demonstrated dedication, integrity, and professionalism in helping to manage APSA—I cannot express enough gratitude for everything the Sherwood Group has done. Beginning on May 1st, we will be transitioning to our new management group, McKenna Management and are assured they will help to continue to grow APSA. I have outlined just a small fraction of the organization’s accomplishments over the past year. The dedicated members of the Executive Council have done tremendous things in all aspects of our organization, and I hope this Annual Meeting will be a showcase of their efforts. I hope you enjoy the Annual Meeting!

Best,

Michael Guo


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APSA 2015 Annual Meeting Committee Welcome

Colleagues, Mentors, and Friends,

On behalf of the 2015 APSA Events Committee, welcome to the 11th Annual Meeting of the American Physician Scientists Association (APSA). We are excited to once again hold this meeting in partnership with the American Society for Clinical Investigation and the Association of American Physicians (ASCI/AAP) joint annual meeting, and the Central Society for Clinical and Translational Research and the Midwestern Section of the American Federation for Medical Research CSCTR/MWAFMR meetings.

Over the past 11 years this meeting has strived to bring unique opportunities to physician-scientists trainees to help expand networking opportunities, educational experiences and the chance to share your work in a highly interactive manner. This year our business meeting has put emphasis on the expansion of our Local Chapter initiatives. To further grow APSA outreach, we know that it starts with our local chapters and we wanted to recognize those chapters that have continuously done an excellent job representing APSA.

The joint APSA/ASCI/AAP meeting described in this booklet is held at the Fairmont Chicago, Millennium Park. The CSCTR/MWAFMR meeting, which all APSA registrants are welcome to attend, is held at the Hotel Chicago (333 N Dearborn Street), within walking distance from the Fairmont from Thursday the 23th until Friday the 24th -- a full schedule of events can be found at www.cscr.com/am15. Furthermore, there is a great social outing with representatives of this society on Thursday at Bar Louie (335 N Dearborn Street).This has been a tradition for the last two years and if you are too late to participate this year make sure to mark it in your calendar next year!

Overall, the entire Events Committee has put a program together with the goals that all attendees can take advantage of the exceptional educational experiences. We focused on Keynote address with a broad area of research interests but most importantly a long history of excellent mentorship. We have invited panelists to share their expertise in question and answer sessions; finally, we have spent time recruiting mentors for you to speak with in a wide array of research/clinical interests. We hope that you use these chances to get to know your colleagues and future mentors well. On behalf of the Events committee I want to welcome you to the APSA 11th Annual meeting!

Sincerely,

Daniel DelloStritto

April 24-26, 2015, Chicago, IL www.physicianscientists.org

510th APSA Annual Meeting April 25-27, 2014

Chicago, IL11th APSA Annual Meeting April 24-26, 2015, Chicago, IL

APSA would like to thank the following members of the Executive Council for their leadership and support in planning this meeting.

Michael Guo President Harvard University Evan Noch Past President Weill-Cornell Medical Center Daniel DelloStritto President-Elect Northeast Ohio Medical University Stephen Chrzanowski Vice President University of Florida Daniel DelloStritto Chair, Events Committee Northeast Ohio Medical UniversityHsin-Pin Lin Chair, Fundraising Committee Northwestern University Peter Mittwede Chair, Membership Committee University of Mississippi Medical CenterJosh Cohen Chair, Partnerships Committee University of Alabama at BirminghamStephanie Jackson Chair, Partnerships Committee Saint Louis University Jennifer Kwan Chair, Policy Committee University of Illinois-Chicago Stephanie Brosius Chair, Public Relations Committee University of Alabama at BirminghamAlexander Adami Chair, Technology Committee University of Connecticut Health Center Andrew M. Harrison Member-at-Large DO-MD/PhD Mayo ClinicAlvin Das Member-at-Large, MD/DO Northeast Ohio Medical University Tyler Zahrli Member-at-Large Social Science and Humanities Saint Louis University Evan Noch Resident Liason Weill-Cornell Medical CenterSofia Campos Undergraduate Liason University of California San DiegoLeanne Dumeny Undergraduate Liason University of FloridaZachary Kiss Undergraduate Liason New York UniversityAaron Adair Executive Director The Kellen GroupJillian Liu Vice-Chair, Events Committee The Ohio State UniversityAnnie Hsieh Vice-Chair, Membership Committee Johns Hopkins UniversityTravis Hull Vice-Chair, Membership Committee University of Alabama at BirminghamJimmy Chang Vice-Chair, Fundraising Committee Northwestern UniversityDanielle Desjardins Vice-Chair, Partnerships Committee Medical University of South CarolinaRyne Ramaker Vice-Chair, Partnerships Committee University of Alabama at BirminghamCarolyn Brokowski Vice-Chair, Policy Commitee Yale University Jung Park Vice-Chair, Public Relations Committee University of IowaAdewunmi Adelaja Vice-Chair, Technology Committee UCLA-CaltechMichelle Bach Vice-Chair, Member-at-Large, Social Sciences Saint Louis University and Humanities

The APSA Executive Council would like to thank the following members of the Advisor Council for their dedication to the strategic planning and development for the APSA organization:

Richard B. Gaynor, MD; Eli LillyFabio Gratton; Sonic Health

William N. Kelley, MD; University of PennsylvaniaJason Mills, MD, PhD; Washington University

Roger Pomerantz, MD; Seres Health

6April 25-27, 2014Chicago, IL www.physicianscientists.orgApril 24-26, 2015, Chicago, IL www.physicianscientists.org

The APSA Executive Council would like to thank the following members of the Board of Directors for their dedication to the advancement of

APSA and physician-scientists in training:

Ivayla Geneva, MD, PhD, Chair; State University of New York-UpstateMoshe Levi, MD; University of Colorado

Jaimo Ahn, MD. PhD; University of PennsylvaniaMichael Guo; Harvard University

Evan Noch, MD, PhD; Weill-Cornell Medical CenterHans Arora, MD, PhD; Cleveland Clinic

Lawrence (Skip) Brass, MD, PhD; University of PennsylvaniaDania Daye, MD, PhD; Brigham and Women’s Hospital

David Engman, MD, PhD; Northwestern UniversityShwayta Kukreti, MD, PhD; UCLA

David Markovitz, MD; University of MichiganKofi Mensah, MD, PhD; Yale

M. Kerry O’Banion, MD, PhD; University of RochesterEric Schauberger, DO, PhD; Medical College of Wisconsin/Children’s Hospital

Jill Baren, MD; University of PennsylvaniaDavid Braun, MD, PhD; Brigham and Women’s Hospital

Oscar Cuzzani, MD, PhD; Abbot Labs, Allergan Inc.

APSA would like to thank the members of the Annual Meeting Committee for their tremendous support, guidance, and tireless leadership in planning this meeting

Daniel DelloStritto Chair Northeast Ohio Medical UniversityJillian Liu Vice-Chair Ohio State University Allyson Palmer Residency Luncheon Chair Mayo ClinicSaranya Wyles Residency Luncheon Mayo ClinicJason Lou Events/Speakers/Grant Panel University of Southern CaliforniaCarolina Soto Panels University of IllinoisVadim Yerokhin Panels Oklahoma State UniversityMariam Bonyadi Panels University of Illinois at Urbana-ChampaignHarish Vasudevan Website Mount Sinai School of Medicine

APSA would like to extend a sincere thank you to the following leadership & administration for their enthusiastic and never-ending assistance in making this joint meeting a reality:

ASCI The Kellen Group Mukesh K. Jain, MD (President) Aaron Adair (APSA Executive Director) John Hawley (Executive Director) Lyn Maddox Kim Santos

AAP Paul Rothman, MD (President) Lori Ennis (Executive Director)


APSA Abstract Travel Awards ($750 each)Deborah Olmstead Krupa SavaliaIndiana University School of Medicine University of Nebraska Medical CenterAllyson Palmer Susan ShenMayo Clinic Washington University in St. LouisSaranya Wyles Layla BarkalMayo Clinic College of Medicine University of WisconsinManouela Valtcheva Amy Guimaraes-YoungWashington University in St. Louis University of IowaKailin Yang Brendan CoutuCleveland Clinic University of MinnesotaDavid Dadey Hanna EricksonWashington University in St. Louis University of Illinois at Urbana-Champaign

APSA Abstract Travel Awards ($1000 each)Katie Hwang Nidhi GuptaBrigham and Women’s Hospital, Harvard Medical School University of Connecticut Health CenterAnnie Wu Amy KuJohns Hopkins Medical Institute Roswell Park Cancer InstituteJennifer Stanley Xiaoxiao LiUniversity of Alabama at Birmingham University of Texas SouthwesternJennifer Watchmaker Shima DowlaVanderbilt University University of Alabama at BirminghamKatelee Barrett Mueller Camila DelgadoTufts Medical Center New York University School of MedicineAlison Gaylo Bianca IslamUniversity of Rochester School of Medicine Georgia Regents University Giraldina Trevejo-Nunez Michael WeintraubUniversity of Pittsburgh Rutgers Robert Wood Johnson Medical SchoolMohamed SolimanWeill Cornell Medical College

AAI Awards ($200 each)Shannon Carty Steven ScovilleUniversity of Pennsylvania The Ohio State UniversityZeguo Zhao Jordan B. JastrabMemorial Sloan Kettering Cancer Center New York University School of MedicineBlair Stocks Vanderbilt University

ASIP Pathology Award ($750)Mohammed DanyMedical University of South Carolina

Local Chapter AwardsUniversity of Alabama-BirminghamSaint Louis UniversityPrinceton University

Joint Meeting Awards ($1000 each)Ayumi Nakamura Jung ParkUniversity of North Carolina at Chapel Hill University of Iowa

Undergraduate Travel AwardsMuna Oli Pooja Yesatharao University of Florida Rice University

8www.physicianscientists.orgApril 24-26, 2015, Chicago, IL www.physicianscientists.org

SAEM Awards ($500 each)Rachel Moore Sethu MadhavanUniversity of California San Diego MetroHealth System, Case Western Reserve UniversityAndrew Ackell Michael GuoUniversity of Iowa Boston Children’s Hospital/Harvard Medical SchoolViral ShahUniversity of IowaASCI/AAP Travel AwardsChristopher Brown Brian CampfieldUniversity of Kentucky University of Pittsburgh School of MedicineDavid Chiang Joseph CichonBaylor College of Medicine New York University School of MedicineRyan Denu Qin GuoUniversity of Wisconsin School of Medicine Harvard Medical SchoolDavid Hartmann Thomas HirschauerMedical University of South Carolina The Ohio State UniversityNelson Hsieh Wei-Chun HsuCase Western Reserve University School of Medicine University of Texas Medical BranchAaron Kaplan Christopher KimUniversity of Buffalo The University of Texas Heath Science Center at San AntonioYoussef A. Kousa Xiaoming LuCollege of Osteopathic Medicine, Michigan State University Cincinnati Children’s Hospital Medical CenterSumera Rizvi John SchellMayo Clinic University of UtahSathish Subramanian Jonathan TucciWashington University in St. Louis Children’s Hospital of Los Angeles, University of Southern Joe Zhao CaliforniaUniversity of Pittsburgh

APSA Founders’ AwardKerry O’BanionUniversity of Rochester Medical Center

Michael “Kerry” O’Banion M.D. Ph.D., is a Professor in the Departments of Neurology and Neurobiology & Anatomy at Rochester University School of Medicine and Dentistry. Dr. O’Banion received his M.D. and Ph.D. from the University of Illinois, School of Medicine. His lab focuses on innate immune activation of the brain, a term now referred to as neuroinflammation and its contributions to the pathogenesis of Alzheimer’s and other brain diseases. Based on his pioneering work in the area of cyclooxygenase-2 and inflammation, he initiated a research program that focuses on understanding the role of neuroinflammation in Alzheimer’s and other neurodegenerative diseases. The main goal is to understand the role of neuroinflammation and oxidative stress in promoting injury and to determine whether therapeutic interventions targeting these processes can alleviate late radiation effects, including cognitive changes. Besides his many academic accolades, Dr. O’Banion has been honored for his vital role in the mentorship of young Physician-Scientists. He has had a vital hand in training over 20 graduate students and post-doctoral fellows. He received the George W. Corner Dean’s Teaching Scholar award and the Graduate Student Society Faculty Teaching Award.


Chicago, IL

Thursday, April 23rdTime Event Location5:00 pm - 6:30 pm Grant-writing for the post-graduate physician-scientist Crystal Room a practical approach to fellowship funding and beyond Robert O. Bonow, MD, American Heart Association Northwestern University (RSVP required to [email protected])

8:30 pm - 12:00 am Social Event with CSCTR and MWAFMR Bar Louie-River North (below Opportunity for APSA members to network with Hotel Chicago) members of CSCTR and MWAFMR

Meeting Agenda


Friday, April 24thTime Event Location8:30 am - 11 am APSA Business Meeting Moulin Rouge8:30 am - 8:35 am Board of Directors Welcome Message Eve Geneva, MD, PhD Chair, APSA Board of Directors, SUNY Upstate 8:35 am – 8:40 am Opening Remarks Michael Guo, President, APSA, MD/PhD Candidate, Harvard University8:40 am - 9:30 am APSA Standing Committee Reports Policy, Finance, Public Relations, Membership, Events, Technology, and Partnerships 9:30 am - 9:45 am Break9:45 am - 10:00 am American Medical Women’s Association (AMWA) presentation10:00 am - 10:30 am Local Chapter Presentations University of Alabama-Birmingham Princeton University Saint Louis University10:30 am - 10:45 am Elections with electronic voting 10:45 am - 11:00 am Closing Remarks Daniel DelloStritto, President-Elect, MD/PhD Candidate, Northeast Ohio Medical University11:00 am - 11:45 am APSA Keynote International Ballroom Perspectives of a Translational Researcher in Emergency Medicine Jeff Kline, MD Indiana University (SAEM Sponsored Talk) 12:00 pm - 12:45 pm APSA Keynote International Ballroom Studying Enteropathogenic E. coli Through the Eyes of a Gastroenterologist: How Clinical Knowledge Impacts the Research Approach Gail Hecht, MD Loyola University, Chicago (AGA Sponsored Talk)

1:00 pm - 3:00 pm Poster Setup Imperial Ballroom1:00 pm - 6:00 pm Plenary Session I: Understanding Disease Mechanisms International Ballroom to Improve Human Health Moderators: Christine Seidman, Mukesh Jain, and Dan DelloStritto

10April 25-27, 2014Chicago, IL www.physicianscientists.org

1:00 pm – 1:30 pm Origins of Cystic Fibrosis Lung Disease International Ballroom Michael Welsh, MD University of Iowa1:30 pm – 2:00 pm Mutations to Medicines: A Precision Medicine Approach to International Ballroom Cystic Fibrosis Jeffrey Leiden, MD, PhD Vertex Pharmaceuticals

2:00 pm - 3:00 pm APSA Panel: Policies Governing Bench to Bedside, Moulin Rouge Entrepreneurship in Biomedical Research Panelists: Francis Collins, MD, PhD, NIH Director Stephen Ostroff, MD, FDA Chief Scientist Christopher Burrow, MD, Humetrix Vice President Lloyd Klickstein, MD, PhD, Novartis Head of Translational Medicine Moderator: Jennifer Kwan, MD, PhD, University of Illinois Chicago2:00 pm - 3:00 pm ASCI and AAP New Member Presentations International Ballroom2:00 pm - 2:15 pm AAP New Member Presentation International Ballroom Testicular Germ Cell Tumors: A Paradigm for Successful GWA Studies in Cancer Katherine L. Nathanson, MD University of Pennsylvania2:15 pm - 2:30 pm ASCI New Member Presentation International Ballroom Liquid Biopsy Approaches for Detecting and Characterizing Human Cancer Victor E. Velculescu, MD, PhD Johns Hopkins University2:30 pm - 2:45 pm AAP New Member Presentation International Ballroom Principles of Resistance to Targeted Anticancer Agents Levi Garraway, MD Harvard University2:45 pm - 3:00 pm ASCI New Member Presentation International Ballroom Mechanistic Roadmap to Human Myocardial Regeneration Hesham A. Sadek, MD, PhD UT Southwestern3:00 pm - 3:30 pm Break International Ballroom Foyer3:30 pm - 6:15 pm Plenary Session II: Understanding Disease Mechanisms to International Ballroom Improve Human Health Moderators: Paul Rothman, Mukesh Jain, and Andrew Harrison3:30 pm - 4:00 pm ASCI Harrington Award International Ballroom Preventing Cervical Cancer and Other HPV-induced Diseases by Vaccination Douglas Lowy, MD National Cancer Institute4:00 pm - 4:30 pm APSA Keynote International Ballroom Time for Rev-erb Nation Mitchell Lazar, MD, PhD University of Pennsylvania4:30 pm - 4:45 pm The Seldin-Smith Legacy International Ballroom Michael S. Brown, MD UT Southwestern Warner C. Greene, MD, PhD Gladstone Institutes


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10th APSA Annual Meeting April 25-27, 2014Chicago, IL

Saturday, April 25thTime Event Location7:00 am - 8:00 am Mentoring Breakfast (ticketed event) Moulin Rouge 8:15 am – 5:45 pm Plenary Session III: Understanding Disease Mechanisms to International Ballroom Improve Human Health Moderators: Linda Fried, Levi Garraway, and Stephen Chrzanowski 8:15 am – 8:45 am New Insights into Vascular Biology in the Eye and Brain International Ballroom Jeremy Nathans, MD, PhD Johns Hopkins University8:45 am – 9:15 am Autism: At the Interface of Neuroscience Genetics and International Ballroom Genomic Medicine Daniel Geschwind, MD, PhD David Geffen School of Medicine, UCLA9:15 am – 9:30 am APSA trainee oral abstract presentation International Ballroom Ayumi Nakamura University of North Carolina at Chapel Hill miR-29: A Molecular Timer that Accelerates Aging9:30 am - 10:00 am Nanotechnology and Regenerative Neurology International Ballroom John A. Kessler, MD Northwestern University Feinberg School of Medicine10:00 am - 10:30 am Break International Ballroom Foyer

10:30 am - 11:45 am Plenary Session IV: Undestanding Disease Mechanisms International Ballroom to Improve Human Health Moderators: Paul Rothman, Levi Garraway, and Jennifer Kwan


4:45 pm - 5:15 pm ASCI Presidential Address International Ballroom Advancing the Mission Mukesh K. Jain, MD Case Western Reserve University School of Medicine5:15 pm - 5:45 pm ASCI/Stanley J. Korsmeyer Award International Ballroom Electrical and Episodic Disorders: Channelopathies and Beyond Louis J. Ptáček, MD University of California, San Francisco5:45 p.m - 6:15 p.m APSA - Lasker Foundation Award Lecture International Ballroom Peregrinations of a Physician Scientists: On Sight and Life Alfred Sommer, MD, MHS, Dean Emeritus Johns Hopkins University6:15 pm - 7:30 pm ASCI President’s Reception (by invitation only) Gold Room6:15 pm - 9:30 pm Poster Viewing Imperial Ballroom 7:00 pm - 9:00 pm No APSA Dinner Outing For recommendations for local restaurants, please see Hotel (Local Restaurants) concierge 9:00 pm - 12:00 am APSA Welcome Reception John Hancock Center Suggested Attire: Business Casual Shuttles will be running from the Fairmont B2 motor lobby to the Hancock Center (and returning to the Fairmont) continuously from 8:30pm Friday wth the last shuttle leaving Hancock at 12:30 am Saturday


10:30 am – 11:00 am The Biology and Biotechnology of CRISPRs International Ballroom Jennifer Doudna, PhD University of California, Berkeley 11:00 am - 11:15 am APSA trainee oral abstract presentation International Ballroom Jung Park University of Iowa Tcfap2c Potentiates Tumorigenesis and Cancer Growth in an Activated Neu Model of Mammary Carcinogenesis11:15 am - 11:45 am iPS Technology, Gene Editing and Disease Research International Ballroom Rudolph Jaenisch, MD, PhD Whitehead Institute, Massachusetts Institute of Technology11:45 am - 1:30 pm Poster Session with Lunch Imperial Ballroom12:45 pm – 1:30 pm Poster Reviewer Meeting Imperial Ballroom 1:30 pm – 2:00 pm Poster Dismantle Imperial Ballroom1:30 pm – 2:00 pm APSA Keynote Speaker International Ballroom Starting at the Bedside: Science in the 21st Century Craig B. Thompson, MD Memorial Sloan Kettering Cancer Center 2:00 pm - 2:30 pm Genetic Insights from a Human Disease Model to Define International Ballroom How the Brain Controls Puberty and Reproduction William Crowley, MD Massachusetts General Hospital 2:30 pm - 3:00 pm Leptin and Neuronal Control of Glucose Metabolism International Ballroom Jeffrey Friedman, MD, PhD Rockefeller University3:00 pm - 3:15 pm Best Poster and APSA Partner Organization Awards International Ballroom3:15 pm - 3:40 pm Break International Ballroom Foyer3:40 pm - 4:00 pm AAP Business Meeting International Ballroom4:00 pm - 4:30 pm AAP Presidential Address International Ballroom Paul Rothman, MD Johns Hopkins University School of Medicine 4:30 pm - 5:00 pm Kober Lecture International Ballroom A Doctor’s Dilemma: Choices Amidst Change Philip Fred Sparline, MD University of North Carolina School of Medicine5:00 pm - 5:45 pm Kober Medal Presentation International Ballroom Recipient: Francis Collins, MD, PhD National Institutes of Health Presenter: David Ginsburg, MD University of Michigan Medical School 6:00 pm - 8:00 pm ASCI Reception for New Members and Young Physician-Scientist Poster Session (invitation only) Speaker: Griffin P. Rodgers, MD, MACP National Institute of Diabetes, Digestive and Kidney Diseases6:00 pm - 7:00 pm APSA Panel: Women in Medicine and Science Crystal Room Panelists: Louise Laurent, MD, PhD, UCSD Claire Pomeroy, MD, MBA, President of Albert and Mary Lasker Foundation Hilary Reno, MD, PhD, Washington University in St. Louis Hanna Stevens, MD, PhD, University of Iowa Moderator: Mariam Bonyadi, MD/PhD Candidate, University of Illinois at Urbana-Champagne


Chicago, IL

7:30 pm - 9:00 pm APSA Dinner & Speaker Moulin Rouge Life as a Physician-Scientist: The Road From Here to There and Everywhere Liise-anne Pirofski, MD Albert Einstein University 7:00 pm - 10:00 pm AAP Reception and Dinner (ticketed event) Imperial Ballroom9:00 pm - 10:00 pm AAP Dinner Speaker Imperial Ballroom Speaker: Peter Agre, MD Johns Hopkins University From Lake Wobegon to Stockholm APSA members join AAP members in the Imperial Ballroom10:00 pm - 12:00 am Dessert Reception (open to all attendees) Imperial Ballroom FoyerSunday, April 26thTime Event Location8:00 am - 9:30 am Interest Groups and Mentorships Moulin Rouge9:30 am - 10:00 am APSA Keynote Gold Room Patents as Proxies: Should Inventions be Used as an Outcome Metric in Medical Research: Richard Ehman, MD Mayo Clinic (RSNA Sponsored Talk)10:00 am - 11:00 am Panel: Ethical Implications and Use of Big Data Gold Room Panelists: Catherine A. Gallagher, PhD, George Mason University Donald Lloyd-Jones, MD, ScM, Northwestern University10:00 am - 11:00 am Panel: What is a Physician Scientist?: MSTP Admissions Crystal Room Panelists: Lawrence (Skip) Brass, MD, PhD, MSTP Director, University of Pennsylvania11:00 am - 12:00 pm Panel: Technological Innovation in Biomedical and Gold Room Translational Research Panelists: Caronda Moore, PhD, University of Nebraska Robert Bacallao, MD, Indiana University Christopher Burrow, MD, Humetrix Vice President Moderator: Jennifer Kwan, MD, PhD, University of Illinois-Chicago 11:00 am - 12:00 pm Panel: Post-Graduate Opportunities Crystal Room Panelists: Dr. Tadataka (Tachi) Yamada, Chief Medical and ScientificOfficerandExecutiveVice-President,Takeda Pharmaceuticals Peng Ji, MD, PhD, Northwestern University12:30 pm - 2:00 pm Residency Luncheon Moulin Rouge Participating Residency Programs: Brigham and Women’s Hospital - Internal Medicine Children’s Hospital Los Angeles (University of Southern California) Cincinnati Children’s Hospital - Pediatric Scientist Development Program Massachusetts General Hospital - Physician Scientist Training Program National Institute of Health Northwestern University - General Surgery The Ohio State University - Physician Scientist Training Program University of California, Los Angeles - Specialty Training and Advanced Research University of Chicago Medical Scientist Training Program University of Iowa Carver College of Medicine - Physician-Scientist Training Program University of Pennsylvania - Internal Medicine/Physician Scientist Pathway Vanderbilt University School of Medicine - Physician-Scientist Training Program


14April 25-27, 2014Chicago, IL www.physicianscientists.org


Jeffrey Kline, MDKeynote Speaker

Friday 11:00 am - 12:00 pmInternational Ballroom

Dr. Jeffrey Kline received his MD from the Medical College of Virginia, and then did an emergency medicine residency followed by a research fellowship at the Carolinas Medical Center. He now serves as Vice Chair of Research in emergency medicine and a professor of physiology. Jeffrey Kline studies blood clots, the people they affect, and the providers who care for those people. His diagnostic research interests focus on human affect analysis, pretest probability and novel breath-based instruments to reduce medical imaging. His human treatment research includes randomized trials of fibrinolysis and inhaled nitric oxide to reduce heart damage from blood clots in the lungs. He derived and validated a decision rule to help emergency physicians reduce unnecessary diagnostic tests for low-risk patients with symptoms of blood clots in the lungs. His current work focuses on using the human face as a diagnostic instrument to further help doctors make smart decisions about diagnostic testing for blood clots. His laboratory work focuses on mechanisms and treatment of acute pulmonary hypertension from pulmonary embolism, animal models of pulmonary embolism, and a nanoparticle-delivered enzyme, plasmin to promote clot lysis without increasing risk. He helped set up an advanced treatment program to treat patients with severe PE in the hospital, and he also created and runs a clinic specifically to allow patients diagnosed with blood clots in the emergency department to treat themselves at home, rather than in the hospital.

Gail Hecht, MD, MSKeynote Speaker

Friday 12-12:45 pmInternational Ballroom

Dr. Gail Hecht earned a MS in Medical Microbiology at the University of MO-Columbia followed by an MD from Loyola University Stritch School of Medicine. She completed her residency in Internal Medicine at the University of MN- Minneapolis and received Fellowship training in Gastroenterology at Brigham and Women’s Hospital, Harvard Medical School, Boston, MA. Most of her career was spent at the University of Illinois-Chicago where she rose to the rank of Professor of Medicine and Microbiology/Immunology and Chief of Digestive Diseases and Nutrition. She was recruited to Loyola University Chicago in 2013 where she is currently Professor of Medicine and Microbiology/Immunology, Chief, Gastroenterology and Nutrition, and Assistant Dean for Medical Student Research. The focus of Dr. Hecht’s research is host-pathogen interactions with specific emphasis on enteropathogenic Escherichia coli. Her goal is to determine how the bacterial effector proteins that are translocated into intestinal epithelial cells by these pathogens alter host cell physiology including tight junction barrier function, active ion transport processes, and the innate immune response. Her research is funded by both the NIH and the VA. She also has an interest in the gut microbiota and its impact on intestinal function and health. She serves as Editor-in-Chief of a new journal Gut Microbes published by Taylor & Francis. Dr. Hecht has been very active in the American Gastroenterological Association functioning as Chair of the Intestinal Disorders Section of the AGA Council, Basic Research Councilor to the Governing Board and ultimately serving as President from 2009-2010, only the second woman to serve in that capacity.



Mitchell Lazar, MD, PhDKeynote Speaker

Friday 4:00- 4:30 pmInternational Ballroom

Dr. Mitchell Lazar is the Sylvan Eisman Professor of Medicine and Genetics, the Chief of the Division of Endocrinology, Diabetes, and Metabolism, and the Director of the Institute for Diabetes, Obesity, and Metabolism at the University of Pennsylvania. He received his undergraduate degree in Chemistry from the Massachusetts Institute of Technology, then received a PhD in Neurosciences and an MD from Stanford University. He trained in Internal Medicine at Brigham and Women’s Hospital and in Endocrinology at the Massachusetts General Hospital before joining the University of Pennsylvania faculty in 1989. Dr. Lazar discovered the circadian nuclear receptor Rev-erba, as well as its heme ligand, transcriptional repression, and interactions with corepressors and histone deacetylases. His work has demonstrated the fundamental importance of Rev-erb and its corepressor complex in the physiology of circadian rhythms and organismal metabolism. Dr. Lazar also discovered that another nuclear receptor, PPARγ, is predominantly expressed in adipocytes and also pioneered the linkage of PPARγ to adipocyte differentiation, insulin resistance, and type 2 diabetes. He also led the way to a genome-wide understanding of PPARγ function, and discovered resistin as a novel adipocyte hormone that impairs insulin action and as the first member of a previouly unknown family of secreted resistin-like molecules. He has given named lectures throughout the world, and has served as a member of the Board of Scientific Councilors of the NIDDK as well as many editorial and scientific advisory boards. He has been elected to the American Society for Clinical Investigation and the Association of American Physicians, and received two NIH Merit Awards, the Van Meter Award of the American Thyroid Association, the BMS Freedom to Discover Award, the Richard Weitzman Award, Edwin B. Astwood Lecture Award and Gerald D. Aurbach Lecture Award from The Endocrine Society, and the Stanley Korsmeyer Award of the American Society for Clinical Investigation. He was elected to the Institute of Medicine of the US National Academy of Sciences in 2006, and to the American Academy of Arts and Sciences in 2008.

Alfred Sommer, MD, MHSKeynote Speaker

Lasker Foundation Award WinnerFriday 5:45-6:15 pm

International Ballroom

Dr. Sommer is a Gilman Scholar and University Distinguished Service Professor at Johns Hopkins University; Johns Hopkins Professor of Epidemiology, Ophthalmology, and International Health; and Dean Emeritus of the Johns Hopkins Bloomberg School of Public Health. He received his MD from Harvard Medical School (1967) and his Master of Health Science in Epidemiology from the Johns Hopkins School of Public Health (1973). He has published 6 books and over 300 scientific articles; has received numerous awards including the Albert Lasker Award for Clinical Research, the Warren Alpert Foundation Prize, and the Duke Elder International Gold Medal for Contributions to Ophthalmology; has delivered over 40 named lectureships, including the Jackson Memorial Lecture (American Academy of Ophthalmology), Duke Elder Oration (Royal College of Ophthalmologists), De Schweinitz Lecture (College of Physicians, Philadelphia), Doyne Lecture (Oxford Ophthalmologic Congress), among others. He is a member of both the U.S. National Academy of Sciences and the Institute of Medicine. His current research interests include child survival and blindness prevention strategies, micronutrient interventions, and the interface between public health and clinical medicine. Sommer has received the Laureate Award of the American Academy of Ophthalmology, and was elected to the ASCRS “Ophthalmology Hall of Fame.”


Craig B. Thompson, MDKeynote Speaker

Saturday, 1:30-2:00 pmInternational Ballroom

Craig B. Thompson, M.D. is the President and Chief Executive Officer of Memorial Sloan-Kettering Cancer Center (MSKCC). Dr. Thompson is a board-certified internist and medical oncologist with extensive research experience in cancer, immunology, and trans-lational medicine. His current research focuses on the regulation of cellular metabolism during cell growth/differentiation and on the role that metabolic changes play in the origin and progression of cancer. Dr. Thompson is a member of the Institute of Medicine, the National Academy of Sciences, the American Academy of Arts and Sciences, and the Medical Advisory Board of the Howard Hughes Medical Institute.

Liise-anne Pirofski, MDIDSA Sponsored Keynote Speaker

Saturday 7:00-9:00 pm Moulin Rouge

Liise-anne Pirofski, MD, FIDSA, is professor of medicine, microbiology, and immunology, the Selma and Jacques Mitrani Professor of Biomedical Research at the Albert Einstein College of Medicine and chief of the Division of Infectious Diseases at the Albert Einstein College of Medicine and Montefiore Medical Center in Bronx, New York. She earned her BA at the University of California, Berkeley, and her MD from Albert Einstein College of Medicine, trained in internal medicine at Bellevue Hospital and New York University Medical Center and in infectious diseases followed by post-doctoral training at Albert Einstein College of Medicine and Montefiore Medical Center. She has had a NIH-funded research program on immunity to encapsulated pathogens for over two decades, served extensively on NIH study sections and external advisory panels on infectious diseases, and is an editor of mBio and Infection and Immunity. She is also a co-developer of the Damage-response framework, an integrated theory of microbial pathogenesis and the pathogenesis of infectious diseases. Dr. Pirofski is a member of the Association of American Physicians and the American Academy of Microbiology and a fellow of IDSA and the American College of Physicians. She has received the Harry Eagle Award for Outstanding Basic Science Teaching and a Faculty Mentoring Award from Einstein and is the 2015 recipient of the ASM William A Hinton Research Training Award.

Richard L. Ehman, MD RSNA Sponsored Keynote Speaker

Sunday, 9:30-10 am Gold Room

Richard L. Ehman, MD, is a Professor of Radiology at the Mayo Clinic and an Emeritus member of the Mayo Clinic Board of Trustees. His research program is focused on developing new imaging technologies. He holds more than 40 patents and many of these inventions have been commercialized and are widely used in medical care. He has served as chair of the Radiology and Nuclear Medicine Study Section of the National Institutes of Health (NIH), as a member of the Advisory Council of the National Institute of Biomedical Imaging and Bioengineering of the NIH, and as a member of the Council of Councils of the NIH. Dr. Ehman was awarded the Gold Medal of the International Society for Magnetic Resonance in Medicine in 1995 for his research contributions and the Outstanding Researcher Award of the Radiological Society of North America in 2006. He was elected to the Institute of Medicine of the National Academies of Science in 2010. Dr. Ehman served as president of the International Society for Magnetic Resonance in Medicine in 2002-2003. He serves on the Board of Directors of the Radiological Society of North America (RSNA) and will be president in 2017. He was president of the Academy of Radiology Research from 2012 to 2014. Dr. Ehman is currently the president of the Society for Body Computed Tomography and Magnetic Resonance.



Robert O. Bonow, MD, MSGrant writing workshop

Thursday 5-6:30 pmCrystal Ballroom

Dr. Robert O. Bonow is the Goldberg Distinguished Professor of Cardiology at the Northwestern University Feinberg School of Medicine and Director of the Center for Cardiovascular Innovation. He served Chief of the Division of Cardiology at Northwestern from 1992 to 2011. Dr. Bonow received his MD degree from the University of Pennsylvania School of Medicine. He has authored or co-authored more than 480 published papers and 105 book chapters. He serves on the editorial boards of 10 medical journals and is one of the four editors of Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine. Dr. Bonow is past-President of the American Heart Association, a Master of the American College of Cardiology and a Master of the American College of Physicians. He has served on the Board of Trustees of the American College of Cardiology, the Board of Directors of the American Heart Association, the Subspecialty Board on Cardiovascular Disease of the American Board of Internal Medicine, the Board of Extramural Advisors of the National Heart, Lung and Blood Institute, and the Clinical Research Roundtable of the Institute of Medicine. Among his honors are the NIH Director’s Award, the U.S. Public Health Service Commendation Medal and Outstanding Service Medal, and elected membership in the American Society for Clinical Investigation and the Association of American Physicians. He is the recipient of the Distinguished Leadership Award, Distinguished Achievement Award, Gold Heart Award, and James B. Herrick Award of the American Heart Association; the Distinguished Fellowship Award and Distinguished Service Award of the American College of Cardiology; the Denolin Award of the European Society of Cardiology; and the John Phillips Memorial Award of the American College of Physicians. An endowed chair was established in his name at Northwestern University in 2012.

Dr. Chris Burrow, a physician-scientist and biotechnology executive/entrepreneur in the field of genomics and personalized medicine has played a leading role at Humetrix in the development of the company’s suite of mobile health care apps to deliver anytime anywhere access to personal medical records. The HHS award winning Humetrix iBlueButton app securely downloads, stores, displays and aggregates Medicare, VA and DoD “Blue Button” summary clinical records and enables patients to conveniently exercise their HIPAA rights to receive electronic summary clinical records directly from clinics and hospitals where they have received care. In the last year, Dr. Burrow has testified before Congress on the subject of FDA regulatory oversight of mobile health apps, spoke on the subject of mobile apps and date privacy at the 2014 FTC Spring Privacy Series focused on consumer controlled clinical data and has worked actively with the HHS Office of the National Coordinator for Health Information Exchange to promote and enable consumer access to their electronic medical records. A graduate of the Baylor College of Medicine, Dr. Burrow trained in Internal Medicine, Nephrology and Molecular Biology at the Johns Hopkins University School of Medicine. As a faculty member first at Hopkins, and then at the Mount Sinai School of Medicine Dr. Burrow was an Attending Physician in Nephrology and an internationally recognized leader in the molecular biology of kidney development.

Francis S. Collins, MD, PhD, is the Director of the National Institutes of Health (NIH). In that role he oversees the work of the largest supporter of biomedical research in the world, spanning the spectrum from basic to clinical research. Dr. Collins is a physician-geneticist noted for his landmark discoveries of disease genes and his leadership of the international Human Genome Project, which culminated in April 2003 with the completion of a finished sequence of the human DNA instruction book. He served as the director for the National Human Genome Research Institute at the NIH from 1993-2008. Before coming to the NIH, Dr. Collins was a Howard Hughes Medical Institute investigator at the University of Michigan. He is

an elected member of the Institute of Medicine and the National Academy of Sciences, was awarded the Presidential Medal of Freedom in November of 2007, and received the National Medal of Science in 2009.

Chris Burrow, MDPolicy Panel

Friday 2-3 pmMoulin Rouge

Francis S. Collins, MD, PhDPolicy Panel



Stephen Ostroff, MDPolicy Panel


Dr. Ostroff is currently the Chief Scientist at the US Food and Drug Administration (FDA) and in April 2015 he will become the Acting Commissioner of the FDA. He joined FDA in 2013 as the Chief Medical Officer in the Center for Food Safety and Applied Nutrition (CFSAN) at the US Food and Drug Administration (FDA) and the Senior Public Health Advisor to FDA’s Office of Foods and Veterinary Medicine before assuming his current position in February 2014. Dr. Ostroff graduated from the University of Pennsylvania School of Medicine in 1981 and completed residencies in internal medicine at the University of Colorado Health Sciences Center and preventive medicine at the Centers for Disease Control and Prevention (CDC). He began his career with the US Public Health Service (USPHS) as a National Health Service Corps assignee to Pohnpei, Micronesia, followed by participating in CDC’s Epidemic Intelligence Service (EIS) assigned to the Washington Department of Health in Seattle. He worked in the Enteric Diseases Branch, the Division of Viral & Rickettsial Diseases, and the Respiratory Diseases Branch in CDC’s National Center for Infectious Diseases (NCID) before becoming NCID’s Associate Director for Epidemiologic Science from 1993-2002 and Deputy Director of NCID from 2002-2005. From 2002 to 2004, he was also Acting Director of CDC’s Select Agent Program. Dr. Ostroff retired from CDC at the rank of Assistant Surgeon General, USPHS in 2005. He then worked in Honolulu as the US Department of Health and Human Services Representative to the Pacific Islands followed by consulting for the World Bank on public health projects in South Asia and Latin America. During 2007-2013, he served as director of the Bureau of Epidemiology in the Pennsylvania Department of Health and was also the Acting Physician General for the Commonwealth of Pennsylvania before joining FDA. Dr. Ostroff is a fellow of the Infectious Disease Society of America and American College of Physicians, has served as special advisor to the International Society for Travel Medicine, President of the Department of Defense’s Armed Forces Epidemiology Board, and President of the Council of State and Territorial Epidemiologists. He currently chairs the Public Health Committee of the American Society for Microbiology’s Public and Scientific Affairs Board and has served on both Institute of Medicine and National Research Council committees.

Lloyd Klickstein, MD, PhDPolicy Panel

Friday, 2-3 pmMoulin Rouge

Dr. Klickstein is Head of Translational Medicine for the New Indication Discovery Unit (NIDU) at the Novartis Institutes for BioMedical Research. NIDU conducts research and early clinical development of compounds for new indications outside current Disease Area strategy, based on medical need and scientific validity. Several of the NIDU programs are industry-leading efforts in new areas of drug development, for example vestibulocochlear diseases and human aging. Prior to co-founding NIDU, Dr. Klickstein was Translational Medicine Head for Musculoskeletal Diseases where he served as a core member of global drug development teams and built an early clinical development group that designed and executed successful Proof-of-Concept studies, one of which has since been commercialized. Prior to joining Novartis in 2006, Dr. Klickstein was an academic physician-scientist at Brigham & Women’s Hospital (BWH) and Harvard Medical School. At BWH, he directed a basic research laboratory focused on the regulation of cell adhesion in the immune system, had an active clinical practice seeing internal medicine and rheumatology patients, and directed the Rheumatology fellowship training program. Dr. Klickstein graduated from Tufts University with undergraduate majors in biology, chemistry and mathematics and subsequently from the Medical Scientist Training Program at Harvard. He is board-certified in Internal Medicine and Rheumatology.

19

10th APSA Annual Meeting April 25-27, 2014Chicago, IL


Hilary Reno, MD, PhDWomen in Medicine Panel

Saturday, 6-7 pmCrystal Room

Louise Laurent, MD, PhD Women in Medicine Panel


Dr. Hilary Reno received her M.D. and Ph.D. from the Medical Scholars Program at the University of Illinois Urbana-Champaign in 2002. Her Ph.D. research field was Entomology, and she worked with the mosquito vector of LaCrosse virus with broad interests in the evolution and ecology of disease. She completed her residency in Internal Medicine at Washington University in St. Louis. After her first year of fellowship in Infectious Disease, she served as a Chief Resident during which she was an editor of The Washington Manual of Medical Therapeutics. She then returned to Infectious Disease fellowship part-time and continued to work part-time until last year. In fellowship, she developed an interest in public health and STIs while serving as Medical Director of the St. Louis County STD clinic. While working part-time in Hospitalist Medicine and Infectious Disease, she developed a novel Resident Night Report and conducted research on STIs. Her current appointment as Assistant Professor in Infectious Disease and Hospitalist Medicine involves clinical teaching and clinical research with a public health focus. Her current research addresses health care delivery in STI care, STIs in patients with HIV, and the high STI rates in the St. Louis Region.

Louise Laurent is an Assistant Professor in Reproductive Medicine at the University of California, San Diego and a recipient of a training fellowship from the California Institute of Regenerative Medicine, a fellowship from the NIH Reproductive Scientist Development Program, and a fellowship from the NIH/NICHD Women’s Reproductive Health Research Career Development Program. She received her residency training in Obstetrics and Gynecology and her clinical fellowship training in Maternal Fetal Medicine at UC San Diego. As a student in the laboratory of Vikas P. Sukatme, M.D., Ph.D., at the University of Chicago, she cloned and characterized EGR1, a zinc finger transcription factor. Her graduate research as a MSTP student at UCSF included a large scale mutagenesis and molecular tracking strategy to define the regions of the HIV genome necessary for viral replication in the laboratory of Patrick O. Brown, M.D. / Ph.D. As a clinical fellow, she worked with Jeanne Loring, Ph.D. at The Scripps Research Institute to delineate the expression of miRNAs in human embryonic stem cells. Her current research focuses on applying genomic and epigenomic methods to understanding the molecular regulation of pluripotency and differentiation, optimizing the preclinical and clinical utility of human pluripotent stem cells, and identifying the molecular basis of placental dysfunction in human pregnancy.

Claire Pomeroy, MD, MBAWomen in Medicine Panel


Claire Pomeroy is president of the Albert and Mary Lasker Foundation. She serves as chief executive officer of the Foundation and is responsible for advancing the Foundation’s mission to “improve health by accelerating support for medical research through recognition of research excellence, public education and advocacy.” An expert in infectious diseases, Dr. Pomeroy is a long-time advocate for patients, especially those with HIV/AIDS, and public health. She passionately supports ongoing investment in the full range of research. She has a special interest in health care policy, with a focus on the importance of the social determinants of health. She has published more than 100 articles and book chapters and edited three books. Dr. Pomeroy serves on the Board of Trustees for the Morehouse School of Medicine and the Board of Directors for the Sierra Health Foundation; the Foundation for Biomedical Research; and PRIDE Industries. She is co-chair of the Blue Ridge Academic Health group. She is a member of the Board of Directors of Expanesthetics, Inc. and of Becton, Dickinson & Company. Dr. Pomeroy was inducted into the Institute of Medicine in 2011. Dr. Pomeroy received bachelors and medical degrees from the University of Michigan and completed her residency and fellowship training in internal medicine and infectious diseases at the University of Minnesota. She earned an MBA from the University of Kentucky. She has held faculty positions at the University of Minnesota, University of Kentucky and University of California (UC) Davis; she is currently professor emerita at UC Davis. Dr. Pomeroy was chief of infectious diseases and associate dean for research and informatics at the University

of Kentucky. She joined UC Davis in 2003 as executive associate dean and in 2005 was appointed vice chancellor and dean of the School of Medicine. She became president of the Lasker Foundation in June 2013.


Hanna Stevens received her B.S. from Cornell University in neurobiology and behavior and then attended the University of Illinois at Urbana-Champaign where she received an MD and PhD in Neuroscience through the Medical Scholars Program. She trained in a unique residency program at the Yale School of Medicine Child Study Center in Adult, Child, Adolescent and Research Psychiatry. She was then recruited to the faculty at Yale where she was the recipient of an NIMH K08 Career Development Award, a NARSAD Young Investigator Award, an APA Research Fellowship, a Klingenstein Third Generation Foundation Fellowship, and a Patterson Clinical Research Award. Hanna recently joined the faculty of the University of Iowa Department of Psychiatry at the end of 2014. She is currently directing a program of research on model systems of early brain development. She is particularly interested in the impact of prenatal genetic and environmental factors on childhood behavioral problems and how early events in brain development relate to the onset of major mental illness, such as depression and schizophrenia, in adolescence and adulthood. The long term goals of her research program are to better understand the etiologies of child and adult mental illnesses and to improve outcomes for pregnant mothers affected by mood and anxiety disorders.

Hanna Stevens, MD, PhDWomen in Medicine Panel


Professor Gallagher focuses on improving the intersection between health care and justice agencies to better meet the needs of high-risk populations and the public health of their larger communities. Her work on justice-involved adolescents has appeared in the Journal of the American Academy of Child and Adolescent Psychiatry, the Journal of Adolescent Health, Social Science and Medicine and Pediatrics. In addition to her primary research, she develops, monitors and analyzes national statistical programs and provides federal agencies with policy guidance, routinely working with the Office of Juvenile Justice and Delinquency Prevention, the Centers for Disease Control, the Agency for Health Care Research and Quality, the Office of the Surgeon General, and the U.S. Bureau of the Census. She led the epidemiological and legal research efforts behind a joint-agency Federal Initiative on Juvenile Justice Health, and currently serves on the Campbell Collaboration’s Crime and Justice Steering Group.

Catherine A. Gallagher, PhDBig Data and Ethics Panel

Sunday, 10-11 amGold Room

Donald M. Lloyd-Jones, MD, ScMBig Data and Ethics Panel

Sunday, 10-11 amGold Room

Dr. Lloyd-Jones’ research interests lie in cardiovascular disease epidemiology, risk estimation, and prevention. A main focus of his research has been investigation of the lifetime risks for various cardiovascular diseases, and factors which modify those risks. Other areas of interest include CVD risk estimation using novel biomarkers, imaging of subclinical atherosclerosis, and the epidemiology of hypertension. His clinical and teaching interests lie in general cardiology, with a focus on prevention. Dr. Lloyd-Jones completed medical school in Columbia University and is a board-certified cardiologist.



Tadataka Yamada, MDPost Graduate Opportunities Panel

Sunday 11 am -12 pmCrystal Room

Dr. Tadataka (Tachi) Yamada is Chief Medical and Scientific Officer, Executive Vice-President and a Board Member of Takeda Pharmaceuticals. He has responsibility for all of Takeda’s research and development activities. He was formerly President of the Bill & Melinda Gates Foundation Global Health Program. In this capacity he oversaw grants totaling over $9 billion in programs directed at applying technologies to address major health challenges of the developing world. Before joining the Gates Foundation Dr. Yamada was Chairman, Research and Development and a Member of the Board of Directors of GlaxoSmithKline. Dr. Yamada was born in Japan, and completed his education in the United States. He graduated from Stanford University with a BA in history and obtained his M.D. from New York University School of Medicine. He trained in gastroenterology at the UCLA School of Medicine and assumed his first faculty position there. He later moved to the University of Michigan where he ultimately became Chairman, Department of Internal Medicine and Physician-in-Chief at the University of Michigan Medical Center before joining GlaxoSmithKline. A scientist and scholar in gastroenterology, Dr. Yamada is the author of more than 150 original manuscripts on the subject and is the editor of The Textbook of Gastroenterology (now in its Fifth Edition). In recognition of his contributions to medicine and science he has been elected to membership in the Institute of Medicine of the National Academy of Sciences (US), the Academy of Medical Sciences (UK) and the National Academy of Medicine (Mexico). He has received an honorary appointment as Knight Commander of the Most Excellent Order of the British Empire (KBE) and been conferred the degree of D.Sci. honoris causa, from five universities. He has also been the recipient of numerous awards including the Distinguished Achievement Award in Gastrointestinal Physiology from the American Physiological Society, the Friedenwald Medal from the American Gastroenterological Association and the Watanabe Prize in Translational Research from Indiana University and Eli Lilly & Co. Dr. Yamada is a Fellow of the Imperial College of Medicine, a Master of the American College of Physicians, a Fellow of the Royal College of Physicians, a Past-President of the Association of American Physicians and of the American Gastroenterological Association. He is currently a member of the Board of Directors of the Clinton Health Access Initiative and of the Council of the Institute of Medicine of the National Academy of Sciences. He has also served as a member of the President’s Council of Advisors on Science and Technology.

Dr. Brass is a graduate of Harvard College and received his MD/PhD from Case Western Reserve University. From there, he completed his residency training in internal medicine before becoming a fellow in Hematology-Oncology at the University of Pennsylvania. He has been a member of the Penn faculty since 1982, served as Vice Chair for Research in the Department of Medicine, and is currently Professor of Medicine and Pharmacology. In 1998, he became Associate Dean and Director of the MD-PhD program. He is actively working at the national level in the development of training programs for physician-scientists and is a past President of the Association of MD-PhD Program Directors and Administrators and a past Chair of the AAMC GREAT group section on MD-PhD training programs. Dr. Brass’s research interests lie in the fields of hemostasis and vascular biology. He is an elected member of the American Society for Clinical Investigation and Association of American Physicians, an Established Investigator of the American Heart Association, and was a recipient of the IXth Biennial Award for Contributions to Hemostasis Research from the International Society of Thrombosis and Hemostasis.

Lawrence (Skip) Brass, MD, PhDMSTP Admissions Panel

Sunday 10 -11 amCrystal Room

Peng Ji, MD, PhDPost Graduate Opportunities Panel

Sunday 11 am -12 pmCrystal Room

Peng Ji M.D. Ph.D., is an Assistant Professor in Pathology at Northwestern University Feinberg School of Medicine. He received his MD from Peking University in China and his PhD from Albert Einstein College. He went on to receive his clinical training in Clinical Pathology at Northwestern. His lab is interested on the characterizations of novel genes in the regulation of mammalian erythropoiesis; and studies of mDia formin proteins in the engraftment and homing of the hematopoietic stem cells. Our major focuses are erythroid

cell terminal differentiation and hematopoietic stem cell biology using various genetic, molecular and cell biology techniques.

22April 25-27, 2014Chicago, IL


Dr. Chris Burrow, a physician-scientist and biotechnology executive/entrepreneur in the field of genomics and personalized medicine has played a leading role at Humetrix in the development of the company’s suite of mobile health care apps to deliver anytime anywhere access to personal medical records. The HHS award winning Humetrix iBlueButton app securely downloads, stores, displays and aggregates

Chris Burrow, MDTechnology Panel

Sunday 11 am -12 pmGold Room

Medicare, VA and DoD “Blue Button” summary clinical records and enables patients to conveniently exercise their HIPAA rights to receive electronic summary clinical records directly from clinics and hospitals where they have received care. In the last year, Dr. Burrow has testified before Congress on the subject of FDA regulatory oversight of mobile health apps, spoke on the subject of mobile apps and date privacy at the 2014 FTC Spring Privacy Series focused on consumer controlled clinical data and has worked actively with the HHS Office of the National Coordinator for Health Information Exchange to promote and enable consumer access to their electronic medical records. A graduate of the Baylor College of Medicine, Dr. Burrow trained in Internal Medicine, Nephrology and Molecular Biology at the Johns Hopkins University School of Medicine. As a faculty member first at Hopkins, and then at the Mount Sinai School of Medicine Dr. Burrow was an Attending Physician in Nephrology and an internationally recognized leader in the molecular biology of kidney development.

Caronda Moore, PhDTechnology Panel


Dr. Moore was born in Detroit, MI. Originally from Jackson, MS, she currently resides in Omaha, NE. She began doing scientific research the summer following high school graduation in a bridge to college program (Science and Technology Access to Research and Graduate Education, STARGE). She graduated with BS in Biology (Pre-medicine) from Jackson State University, 2005 where she served as a student researcher and campus leader during matriculation at JSU. She spent undergraduate and graduate summers serving as a research intern at different research institutions around the country including, Texas A&M University, Medical college of Wisconsin, University of Nebraska Lincoln, UC Berkeley and Lawrence Livermore Laboratory. She studied Biology on a Master’s level one year before transferring to a PhD Program. She received a PhD in Medical Science from the Department Pharmacology & Experimental Neuroscience at University of Nebraska Medical Center, 2013. She has won several awards for research activities including international travel grants to present worldwide. She has helped train high school, undergraduate, graduate, and medical students in scientific research, has lectured both in and outside of the country and has several scientific research publications. She currently works on the business and legal side of science and healthcare working at UNeMed Corporation, the technology transfer office for the University of Nebraska Medical Center, where we work to protect and commercialize scientific ideas so that they may be utilized by the public.

Robert Bacallao, MDTechnology Panel


Dr. Robert Bacallao is an Associate Professor of Medicine in the division of Nephrology at Indiana University. His scientific focus has centered on the question as to how epithelial cells organize to form a functioning epithelium. Epithelial cells perform the absorptive and secretory functions of an organism and these activities frequently require the generation of tremendous ionic, electrical and pressure gradients. These gradients are achieved by the unique structural and functional organization of epithelial plasma membranes. He has studied how this organization is achieved by examining processes that disrupt the polarized features of epithelial. Ischemic injury has been shown to cause profound derangements in epithelial organization and this is an area of intensive investigation in my laboratory. A second disease process that has been shown to disrupt the polarized phenotype of epithelial cells is autosomal dominant polycystic kidney disease (ADPKD). Protein sorting defects and Golgi complex dysfunction have been described in epithelial cells derived from ADPKD kidneys. A gene responsible for this disease has recently been identified and has been called PKD1. Computer analysis of the PKD1 gene sequence suggests that the gene product is a transmembrane protein which interacts with the extracellular matrix. However, a definitive function for the PKD1 gene product has not been discovered. His lab employs a variety of biochemical, molecular and cell biology methods to address these scientific questions.

2311th APSA Annual Meeting April 24-26 2015, Chicago, IL

Interest Group MentorsInfectious DiseasesInfectious Diseases Society of America

1. Mary E Klotman, MD Chief, Department of Medicine Professor of Medicine, Pathology, Molecular Genetics and MicrobiologyDuke University Medical Center

2. Mitchell Grayson, MDMedical College of Wisconsin

PediatricsSociety for Pediatric Research

1. Kenan Onel, MD, PhD Associate Professor of PediatricsDirector, Pediatric Familial Cancer ClinicUniversity of Chicago

2. Juliane Bubeck Wardenburg, MD, PhDAssociate Professor, Departments of Pediatrics and MicrobiologyThe University of Chicago

3. Eric Beyer MD, PhDProfessor of Pediatrics, Cell Physiology, Cancer Biology and Molecular MedicineUniversity of Chicago

Emergency MedicineSociety for Academic Emergency Medicine & American College of Emergency Physicians

1. Amy Kaji, MD, PhDDirector, South Bay Disaster Resource Center, Associate Professor of Clinical MedicineHarbor UCLA Medical Center

2. Jeffrey Kline, MD Indiana UniversityPsychiatry

1. Hanna Stevens, MD, PhDAssociate Professor in Psychiatry University of Iowa

RadiologyRadiological Society of North America 1. Richard Ehman, MD Professor Mayo ClinicPathologyAmerican Society for Investigative Pathology & Intersociety Council for Pathology Information

1. Christopher Weber, MD, PhDAssistant ProfessorThe University of Chicago

CardiologyAmerican Heart Association

1. Hossein Ardehali, MD, PhDAssociate Professor in Medicine-Cardiology, Molecular Pharamacology and Biological ChemistryNorthwestern University Feinberg School of Medicine

2. Howard Rockman, MDProfessor of Medicine, Cell Biology, Molecular Genetics and MicrobiologyDuke

GastroenterologyAmerican Gastroenterological Association & American Society for Clinical Investigation

1. Vincent Yang, MD, PhD

www.physicianscientists.org24

April 24-26 2015, Chicago, IL www.physicianscientists.org

Professor and Simons Chair of MedicineStony Brook University School of Medicine

2. Fred Gorelick, MD, PhDProfessor of Medicine, Cell BiologyYale

3. John M. Carethers, MD John G. Searle Professor and Chair of the Department of Internal Medicine University of Michigan 4. M. Bishr Omary, MD, PhD Professor of Medicine, Professor and Chair, Molecular and Integrative Physiology University of MichiganNeurosurgery 1. David Frim, MD, PhD Professor of Neurology and Pediatrics; Chief, Section of Neurosurgery University of Chicago 2. Matthew Tate, MD, PhD Assistant Professor in Neurological Surgery and Neurology Northwestern UniversitySurgeryAmerican Society for Clinical Investigation

1. Jaimo Ahn, MD, PhDAssistant Professor of Orthopaedic SurgeryUniversity of Pennsylvania

Hematology/OncologyAmerican Society for Clinical Investigation

1. Lawrence (Skip) Brass, MD, PhDProfessor of Medicine, Director of MSTPUniversity of Pennsylvania

2. Hidayatullah G Munshi, MD Associate Professor in Hematology/Oncology and Otolaryngology-Head and Neck Surgery Northwestern University Feinberg School of MedicineInternal Medicine/ Research-track Residency

1. Brittaney Weber, MDResident in MedicineBrigham and Women’s & Massachusetts General

Dermatology 1. Nicole Najor, PhD Northwestern UniversityPulmonology

1. Ted Standiford MD Professor, Chief of Pulmonary Medicine University of Michigan2. Marc Peters-Golden, MD Professor of Medicine, Associate Director Fellowship Program in Pulmonary Critical Care University of Michigan3. Gokhan Mutlu, MD Adjunct Professor in Medicine Northwestern University4. Scott Budinger, MD Professor in Medicine Northwestern University


Announcements:

Members: Get Involved!Apply for National Leadership Positions

Applications open NOW!!

Take advantage of specialty-specific mentoring through our interest groupsResources available through our website: www.physicianscientists.org

Mark your calendar for APSA’s Regional Meetings!

APSA South Regional MeetingTexas A&M University

Round Rock, TX, Saturday, October 23, 2015

APSA Southeast Regional MeetingVanderbilt University

Nashville, TN, September 19-20, 2015

APSA Northeast Regional Meeting Date and Location TBD

APSA Midwest Regional MeetingSt. Louis University

St. Louis, MO, Saturday, October 23, 2015

APSA West Regional MeetingUniversity of Southern Californa,

Los Angeles, CA, Saturday, November 15, 2015

Work with APSA and support our mission!For MD/PhD programs and medical schools: Become an Institutional Member today and receive a discount on membership dues for all your studentsFor residency programs: Participate in our annual residency luncheon through sponsorshipFor anyone: Sponsor the 2016 APSA Annual Meeting Donate to APSA and its goal of training the future generation of physician-scientists Advertise on the APSA website, in the APSA newsletter, and at our Regional Meetings

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11th Annual Meeting • April 24-26, 2015

The Fairmont HotelMillennium ParkChicago, IL USA

Program design by Stephanie BrosiusPhotographs by Alexander Adami

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