rraappiidd eevvaalluuaattiioonn gguuiiddee ......silvia acosta de gnass, maria paz ade, laura araya,...

29
1 R R A A P P I I D D E E V V A A L L U U A A T T I I O O N N G G U U I I D D E E F F O O R R H H O O S S P P I I T T A A L L P P R R O O G G R R A A M M S S F F O O R R P P R R E E V V E E N N T T I I O O N N A A N N D D C C O O N N T T R R O O L L O O F F N N O O S S O O C C O O M M I I A A L L I I N N F F E E C C T T I I O O N N S S Washington, D.C. 2nd Edition, 2011 PAN AMERICAN HEALTH ORGANIZATION Health Surveillance and Disease Prevention and Control Area International Health Regulations, Alert and Response and Epidemic Diseases

Upload: others

Post on 16-Aug-2021

0 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

1

RRRAAAPPPIIIDDD EEEVVVAAALLLUUUAAATTTIIIOOONNN GGGUUUIIIDDDEEE FFFOOORRR

HHHOOOSSSPPPIIITTTAAALLL PPPRRROOOGGGRRRAAAMMMSSS FFFOOORRR PPPRRREEEVVVEEENNNTTTIIIOOONNN AAANNNDDD CCCOOONNNTTTRRROOOLLL OOOFFF

NNNOOOSSSOOOCCCOOOMMMIIIAAALLL IIINNNFFFEEECCCTTTIIIOOONNNSSS

Washington, D.C.

2nd Edition, 2011

PAN AMERICAN HEALTH ORGANIZATION

Health Surveillance and Disease Prevention and Control Area

International Health Regulations, Alert and Response and Epidemic Diseases

Page 2: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

2

Acknowledgments

This guide was produced based on an original idea by Gabriel Schmunis and counted with the

contributions of Latin American experts in prevention and infection control -

Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola

Brenner, Teresa Camou, Liliana Clara, Erna Cona, Alessandra Santana Destra, Silvia Fonseca,

Amparo Gordillo, Jorge Matheu, Fernando Otaiza, Pilar Ramon- Pardo, Roxane Salvatella, Gabriel

Schmunis, Valeska Stempliuk, Maria Enilda Vega, Natallie Weiller and Martín Yagui.

This publication has been made possible by the sponsorship and cooperation of the United States

Agency for International Development, Bureau for Latin America and the Caribbean, Office of

Regional Sustainable Development (grant LAC-G-00-07-00001-00) and the United States Centers

for Disease Control and Prevention (Cooperative Agreement Number 5U51/CI 000450-04).

Page 3: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

3

Contents

Preface.....................................................................................................................................4

Introduction ............................................................................................................................4

General considerations .....................................................................................................4

Instructions for application of the rapid evaluation guide for nosocomial infection

programs .................................................................................................................................6

General instructions..........................................................................................................6

Instructions and recommendations for interviews ..........................................................6

Instructions and recommendations for document review...............................................7

Instructions and recommendations for direct observation .............................................8

Specific instructions ..........................................................................................................8

Written Report ..................................................................................................................9

Records .............................................................................................................................9

People to interview...........................................................................................................9

Proposed program ..........................................................................................................10

Glossary.................................................................................................................................10

Rapid evaluation guide for nosocomial infection programs ................................................15

AREA: ORGANIZATION ..........................................................................................................16

AREA: EPIDEMIOLOGICAL SURVEILLANCE OF INFECTIONS ..................................................17

AREA: MICROBIOLOGY..........................................................................................................18

AREA: INTERVENTION STRATEGIES......................................................................................20

AREA: STERILIZATION AND HIGH-LEVEL DISINFECTION .......................................................22

AREA: PERSONNEL HEALTH...................................................................................................23

AREA: HOSPITAL ENVIRONMENT AND SANITATION ............................................................24

AREA: INEFFECTIVE PRACTICES .............................................................................................26

AREA: NEONATOLOGY ..........................................................................................................28

Page 4: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

4

Preface There is no doubt that infections associated with health care (nosocomial infections) pose a

problem, affecting approximately one out of twenty hospital patients. Programs for infection

prevention and control have demonstrable benefits in reducing related morbidity and mortality

and hospital costs. One of the best ways to improve the effectiveness of a program for prevention

and control of infections is through systematic and rigorous evaluation of the structural,

functional, and practical elements that have to be implemented in hospitals. Evaluations, whether

they are external or internal, make it possible to identify those areas requiring additional efforts to

comply with standards, to evaluate the strengths of institutions in comparison with their peers,

and to set priorities for interventions from the national level.

Evaluations also have formative effects on human resources of the institutions that are evaluated.

There can be an immediate effect in improvement or correction of practices, in particular, for the

prevention of nosocomial infections. However, the lack of available tools has meant that

evaluations of the programs and practices of prevention of communicable diseases have not been

made part of program routine. PAHO developed this tool in 2005, and it has been validated

through its application in the field in a number of countries of Latin America. The application of

this tool is thus based on direct observation of practices in visits carried out jointly by national and

international professionals.

After five years of the first edition, the increase of scientific evidence has made it necessary to

update the original instrument, while maintaining the same purpose and functionality. This second

edition also includes a specific annex on neonatology, expanding its objective and scope. The

addition of this new area comes at the request of the countries, given the large number of hospital

infection outbreaks in these services. It is expected that this guide will maintain its usefulness and

be used within the health services to direct implementation and maintenance of programs and

practices for control of nosocomial infections.

Introduction General considerations The purpose of this guide is to provide orientation for hospital directors on review and

improvement of the nosocomial infection programs that all such facilities should have. According

to the experts, a well-developed program in the areas currently considered necessary will contain

the components and characteristics described in this guide. It is recommended that, before an

evaluation, hospitals to be evaluated be informed about the visit and its objectives, and that they

have access to this guide.

Page 5: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

5

The purpose of this guide is to provide a general overview rather than specifics on the status of

Infection prevention and control (IPC) activities. Therefore, it does not consider the risk of

individual patients or specific cases. By nature, it is intended only as an instrument to provide

support for an external assessment of the status of the program. It should not be considered an

accreditation system. Furthermore, it does not consider other aspects related to care outside of

surveillance, prevention, and control of nosocomial infections.

The development and use of the first edition of the Guide were possible thanks to the support and

cooperation of the Office of Regional Sustainable Development, Bureau for Latin America and the

Caribbean, U.S. Agency for International Development and the Centers for Disease Control and

Prevention of the United States of America and the experts of several countries. For its

development, specialists in nosocomial infections and microbiologists of several countries met to

lay out the principal and essential points that all hospitals should implement in terms of hospital

IPC. This guide was applied successfully in 67 hospitals, including public, private, and other

hospitals, in 7 countries of the Region of the Americas, involving national and international experts

and PAHO staff. Although the programs evaluated presented quite different levels of compliance

for the indicators evaluated, the contents of the guide were sufficient for evaluating the different

hospitals and their programs for prevention and control of nosocomial infections1.

After 5 years of the first edition, given the additional scientific knowledge accumulated during this

period, the updating of the guide became necessary. Again experts from several countries were

invited to participate. The result is a second edition that maintains the general evidentiary

principles and applicability of the previous edition. This edition also includes annex for for

prevention of infection in the neonatology area.

Description of the guide

The guide provides information on a number of aspects that, according to a group of Latin

American experts, should be included in HAI prevention and control programs. These aspects have

been organized in eight areas that include similar topics. In each area, some components

considered to be essential in a good infection program have been selected. In each component,

the characteristics considered to best describe an acceptable component have been established.

Then, indicators have been established so that the presence of the characteristics could be

considered objectively. A single characteristic may have several indicators and a single component

may have several characteristics. One or more verifiers (“suggested verifiers”) have been proposed

for each indicator. These simply offer orientation or sources of information for the evaluators that

can be used to determine whether a certain indicator is present. The evaluators can use other

methods to establish the presence of indicators.

According to this guide, evaluation of the nosocomial infection program is based solely on the

presence of indicators. The existence of the characteristics and components is based on analysis of

the indicators used for evaluation.

The only exception to the above is the “INEFFECTIVE PRACTICES” area, in which the presence of

any of the indicators is considered in a comment to the report.

Page 6: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

6

Instructions for application of the rapid evaluation guide for nosocomial infection programs

General instructions This guide is designed to be applied within a short period of time (approximately 8 hours per

person with one team of 4 people).

• All actions carried out during an evaluation have a well-defined purpose that should be made

known during the activity.

• Take written notes on your observations at the time. Do not rely on your memory.

• The written report must be compatible with the oral comments made during the visit.

Instructions and recommendations for interviews

This process includes three main types of interviews:

Ι. Initial interview: This interview is usually with the hospital director, who may or may not

be accompanied by other people. The objectives are as follows:

• Introduction to the local authority.

• Meet the people who will accompany the evaluators during the activity.

• Become familiar with the general characteristics of the hospital.

• Explain which activities will be conducted in the hospital during the evaluation.

• Set a time for the final meeting.

• Confirm that the local authority has consented to the activity.

ΙΙ. Technical interviews: These interviews are with professionals who perform different

activities in the hospital. The objective is to obtain specific information related to the guide.

In order to make the most of these interviews, the following is recommended:

• You should always be accompanied by a professional from the hospital

• Interview the person in charge of the unit or activity. A meeting with personnel working

under him or her should be held only with his or her consent.

• Introduce yourself and explain the reason for the interview.

• Tell them what information is required.

ΙΙΙ. Final interview: This interview is usually with the hospital director, accompanied by other

people. This objectives of this interview are as follows:

• Report the main findings of the observations.

o Briefly summarize each area, highlighting aspects that are partially or fully

acceptable as well as those that can be improved. Use clear examples. Avoid going

into detail.

• Compile any information that was not included previously.

• Receive comments and clarifications on your observations.

• Thank the facilities and the appropriate individuals for having participated in the activity.

Page 7: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

7

It is recommended strongly that the evaluation team meet alone for a few minutes before the final

interview and agree on the points that will be dealt with.

Instructions and recommendations for document review Some of the information will be obtained from documents that directly or indirectly contribute

data that can be used as a basis for determining compliance with the characteristics in the guide.

Document review tends to be a long and complex process. For document review:

• Focus the document review on the objectives of the guide.

• Request that your local contacts indicate where the information is found in the documents.

Review by a person unfamiliar with the local documentation system may be tedious and

fruitless. Be explicit about your needs.

• Avoid requesting a particular document. It is preferable to request documentation for the

activities. Each hospital has its own form of documentation.

For example: In order to find out about training activities, avoid requesting “committee

minutes” since the information needed may not be found there. However, if you request

a list of training activities carried out, there may be different types of documentation (e.

g., annual summaries of activities and specific training reports).

Page 8: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

8

Instructions and recommendations for direct observation Evaluation of many of the characteristics is based on observation of how activities are conducted

in practice.

• When direct observation activities are conducted, tell your contacts your expectations before

beginning observation. After completing the observation, summarize whether what you found

met expectations or the practices did not meet the requirements.

• Be cautious about your comments and your reactions to noncompliance with best practices,

particularly because the visits are often accompanied by personnel who may have a partial or

distorted understanding of the practices.

• If you observe failure to comply with techniques or inappropriate practices, it is important to

take note and possibly mention it at the meeting. However, this does not necessarily mean

that it represents a trend unless the practice is repeated.

Specific instructions Some areas have special conditions to be evaluated.

AREA: INTERVENTION STRATEGIES This is one of the most important areas of the evaluation. It is also usually the area in which

there are the greatest numbers of observations. In order to evaluate this area, fill out the

“PREVENTION AND CONTROL STRATEGIES RECORD FORM.” Each indicator refers to the

summary of one of the columns on the RECORD FORM.

The evidence-based concepts used to evaluate the preventive strategies are only some of the

best well-known and least controversial concepts. Therefore, they should be included in the

usual practice of all hospitals.

AREA: INEFFECTIVE PRACTICES There are a series of practices that have been introduced in the past in hospitals to prevent

infections but which do have bases to support their effectiveness. That is, it has been

documented that they do not prevent infections. In some cases, there is even enough

information to advise their elimination because they increase the risk of infection.

In this evaluation it is enough to take note and confirm the presence of an ineffective measure

that increases the risk of infection in order to include a comment about it in the final review

and the written report. Information on the presence of ineffective measures may be acquired

from multiple sources. It often occurs by chance during observations in the clinical units.

AREA: NEONATOLOGY This area includes all aspects of prevention of hospital infection, as well as prevention of

vertical transmission from mother to child. Experts agree that these points should be included

in hospital practices for IPC.

Page 9: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

9

Written Report

Instructions and recommendations for the preparation of the report

• When the field activities have been completed, a final written report should be prepared.

• It is recommended that the report be written on the same day as the evaluation was made,

particularly if more than one hospital has been evaluated that day.

• This is an activity that should be carried out by the entire team. If more than one hospital has

been evaluated on the same day, it is recommended that the hospitals be analyzed one at a

time.

Records Indicate whether or not each indicator in the guide is present by recording YES, NO, or PARTIAL.

Whenever NO or PARTIAL is recorded, a brief written description of the actual status should be

provided so that there can be records for local follow-up. UNEVALUATED should only be recorded

in extraordinary circumstances, and the reason should be explained.

People to interview

• Director

• Person in charge of the IPC Program or Committee

• IPC nurse

• Medical epidemiologist

• Microbiologist

• Sterilization supervisor

• Unit chiefs for intensive care, pediatrics, and surgery

• Head of nursing

• Personnel health supervisor

Page 10: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

10

Proposed program

Activity Estimated

duration

minutes

Number of

evaluators

Objective

Initial interview 40 All Presentation set final meeting.

Meeting with technical committee 90 to 120 1

recommended: all

Review of information, documents,

evaluates the organization and

surveillance.

Sterilization 45 to 60 1 Evaluate the sterilization and

disinfection processes.

Laboratory 30 to 45 1 Evaluate microbiology.

Intensive Care Unit 30 to 45 1

Pediatrics 30 to 45 1

Surgery 30 to 45 1

Medicine 30 to 45 1

Visit to

services

Other services,

depending on time

available.

30 to 45 1

Evaluate intervention strategies.

Integration of the program into

routine practice.

Aspects of the physical plant and

environmental sanitation.

Identify ineffective practices.

Meeting with personnel health

supervisor 30 to 40 1 Evaluate personnel health.

Meeting with governing body 30 to 60 All Oral report on findings.

Writing report 120 to 180 All Prepare report.

Glossary

access

In this document this refers to the situation in which a hospital

provides a service that is not necessarily directly under it. For

example, it may not have a microbiology department. Rather,

the service is provided by an external laboratory on a timely

basis whenever required. In this case it has “access” to

microbiology.

annual discharges Includes normal discharges, discharges due to death, and

transfers, over the period of a year.

annual occupied bed days

Based on a daily count of the number of patients in the patient

care location. This count is recorded at the same time every

day. Daily totals are summed up at the end of the month, and

monthly totals summed up at the end of the year.

basic HAI indicators Minimum ongoing information that a hospital should have in

Page 11: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

11

order to determine infection status. The following infections

are included in this minimum: central venous catheter-related

sepsis, catheter-associated urinary infections, pneumonias

associated with mechanical ventilation, surgical site infections

by type of operation, and puerperal endometritis by type of

delivery. These indications may be different if an

establishment has other frequent high-risk procedures.

biological sterilization controls

Biological controls are currently the only available means to

confirm sterilization of an article or to determine the

effectiveness of the sterilization process.

Bowie-Dick test

This is a method for evaluating the effectiveness of the

vacuum system of an autoclave, by measuring the presence or

absence of air or other gases in the sterilization chamber that

can hinder rapid and uniform penetration of the steam into

the contents being sterilized.

chemical sterilization controls

These tests are based on chemical reactions and are sensitive

to the parameters of the different sterilization methods

(saturated steam, temperature, and time). They contain paper

strips printed with ink and other non-toxic reagents that

change color when the requirements for the process are met.

disinfection

Procedure designed to eliminate pathogenic agents from

articles and other patient care equipment in order to decrease

the risk of infection. Microbial spores are not usually

eliminated. Different levels are distinguished using Spaulding's

classification. High-level disinfection is of particular interest.

epidemiological surveillance

Ongoing information system on diseases (usually infectious

diseases), in the population in order to determine their

frequency, risk factors, morbidity, and mortality, for early

detection of epidemics.

evidence Certainty derived from studies on a given subject that are

currently considered to be conclusive. This usually includes,

Page 12: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

12

but is not limited to, several controlled clinical trials with

concordant conclusions.

external performance

evaluation

System for retrospective and objective comparison between

laboratories, organized by an independent external entity.2

goals

Quantified objectives expected to be achieved. They are

usually expressed numerically in ratios, rates, proportions, or

other similar indicators.

guide

Document with recommendations for action on a given

subject. The subjects are usually technical, and the

recommendations are not compulsory.

healthcare associated

infection (HAI)/ nosocomial

infections (NI) /hospital

infections

Infection that occurs during or as a result of hospitalization,

and was not present or in incubation at t he time of patient

admission. This definition does not distinguish between severe

and minor infections, or between preventable and non-

preventable infections.

high level disinfectants with

proven effectiveness

Formulations based on glutaraldehyde, >2%;

orthophthalaldehyde (OPA), 0.55%; hydrogen peroxide, 7.5%;

peracetic acid, >0.2%; hydrogen peroxide, 7.35%. and

peracetic acid, 0.23%; hydrogen peroxide, 1%, and peracetic

acid, 0.08%.

immunization coverage

Proportion of persons vaccinated of the total planned. For this

guide, no distinction is made whether or not the

immunological response to the vaccine was evaluated.

immunization program

Activities designed to vaccinate a given population, which

establishes who should be vaccinated, which vaccines should

be used, dosages, methods, periodicity, and any other relevant

characteristics of immunization.

invasive procedure

Clinical procedure that includes mechanical disruption of the

body's defense barriers (e. g., skin perforation or insertion of

catheters that change the normal flow of fluids.

major surgeries A major surgery is any procedure carried out in an operating

Page 13: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

13

room that requires incision, excision, manipulation, or suture

of a tissue. It usually requires local anesthesia, general

anesthesia, or deep sedation to control pain.1

management of personnel

with/exposed to infections

Perform rapid diagnosis and appropriate post-exposure

prophylaxis following accidents in the workplace

manual

Reference document that organizes and summarizes the

regulations, instructions, procedures, or any other type of

information, usually operational, on a specific subject.

medical sharps box

A container for disposing safely of sharp objects sued. The

medical sharps box should safely contain contaminated sharp

objects: immediately after use; during temporary storage; and

during transport and handling up to the point of final

treatment and disposal.

official document

Document that meets local requirements to be considered

obligatory for familiarity and compliance. At minimum it must

have the signature of the person in charge of the hospital.

orientation program

Organized training activities to ensure that recently hired

personnel are familiar with the hospital's technical and

administrative procedures.

professional Worker with a university education and degree.

program Organized set of resources and activities to attain a known

end. It also includes objectives, goals, and persons responsible.

routine Customary practice without a rationale that is performed

according to current practice.

standard Standing order that must be complied with.

sterilization

Procedure designed to eliminate all forms of microbial life

from articles and other patient care equipment in order to

decrease the risk of infection.

structures responsible for the

program

A specific stable unit or service that includes those responsible

for the safety of clinical activities (departments or unit chiefs).

In addition to the individuals themselves, this includes their

Page 14: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

14

method of communication and the hierarchical structure of

the organization.

supervision

Process of observation for measuring compliance with

standards, instructions, care procedures, or other

characteristics of daily practice.

1 ALIANZA MUNDIAL PARA LA SEGURIDAD DEL PACIENTE. SEGUNDO RETO MUNDIAL POR LA

SEGURIDAD DEL PACIENTE. LA CIRUGÍA SEGURA SALVA VIDAS. Organización Mundial de la Salud.

http://whqlibdoc.who.int/hq/2008/WHO_IER_PSP_2008.07_spa.pdf

2 Curso de Gestión de calidad y buenas prácticas de laboratorio. II Edición, Washington, D.C.,

2009.http://new.paho.org/hq/index.php?option=com_content&task=view&id=1077&Itemid=12

73&lang=e

Page 15: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

Rap

id e

valu

atio

n g

uid

e fo

r n

oso

com

ial i

nfe

ctio

n p

rogr

ams

DE

SC

RIP

TIO

N O

F H

OS

PIT

AL

Eva

lua

tio

n d

ate

:

Na

me

of

the

ho

spit

al:

Cit

y:

Co

un

try

:

Ad

min

istr

ati

ve s

tatu

s:

s

tate

p

riva

te

u

niv

ers

ity

O

the

r:

Be

ds:

A

nn

ua

l d

isch

arg

es:

An

nu

al

occ

up

ied

be

d d

ay

s:

Be

ds

in I

nte

nsi

ve

Ca

re U

nit

(IC

U):

M

icro

bio

log

y l

ab

ora

tory

:

ICU

be

ds

for

ad

ult

s:

Nu

mb

er

of

iso

lati

on

s/y

ea

r:

ICU

be

ds

for

pe

dia

tric

s:

Nu

mb

er

of

an

tib

iog

ram

s/y

ea

r:

ICU

be

ds

for

ne

on

ato

log

y:

Clin

ica

l Se

rvic

e

# A

nn

ua

l d

isch

arg

es

#

An

nu

al

ma

jor

surg

eri

es

or

chil

db

irth

s

Su

rge

ry

Ob

ste

tric

s

Pe

dia

tric

s

Inte

rna

l m

ed

icin

e

Ne

on

ato

log

y

Ad

ult

in

ten

siv

e c

are

Ma

rk t

he

cli

nic

al

or

surg

ica

l

serv

ice

s th

at

the

ho

spit

al

ha

s

Oth

er

sub

spe

cia

ltie

s

Na

me

s a

nd

po

siti

on

s o

f th

e p

eo

ple

in

terv

iew

ed

:

Na

me

s o

f e

valu

ato

rs:

Page 16: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

16

AR

EA: O

RG

AN

IZA

TIO

N

Co

mp

on

en

ts

Ch

arac

teri

stic

s

Ind

icat

or

Su

gge

ste

d v

eri

fie

r

Pre

sen

t?

There is an o

ffic

ial

do

cum

en

t* d

esi

gn

ati

ng

th

ose

re

spo

nsi

ble

fo

r

IPC

in

th

e h

osp

ita

l.

Do

cum

en

t si

gn

ed

by

lo

cal

au

tho

rity

.

Th

e f

un

ctio

ns

for

ea

ch p

ers

on

re

spo

nsi

ble

are

la

id o

ut.

D

ocu

me

nt

sig

ne

d b

y l

oca

l

au

tho

rity

.

The

str

uct

ure

s re

spo

nsi

ble

* fo

r In

fect

ion

Pre

ven

tio

n

and

Co

ntr

ol (

IPC

) in

th

e

ho

spit

al a

nd

th

e d

ivis

ion

of

resp

on

sib

iliti

es

ha

ve b

ee

n

de

fin

ed

. T

he

pe

rso

nn

el

resp

on

sib

le f

or

IPC

are

at

a h

igh

le

vel

wit

hin

th

e

inst

itu

tio

n.

Do

cum

en

t si

gn

ed

by

lo

cal

au

tho

rity

.

Th

ere

are

an

nu

al

go

als

* f

or

IPC

fo

r th

e h

osp

ita

l.

Off

icia

l d

ocu

me

nt

of

the

inst

itu

tio

n (

pro

gra

m,

pla

n

or

an

nu

al

rep

ort

).

Th

ere

is

evi

de

nce

th

at

de

cisi

on

s a

re m

ad

e t

o a

chie

ve t

he

go

als

.

Min

ute

s, r

ep

ort

s, o

r

inte

rve

nti

on

pro

gra

ms.

Lead

ers

hip

IPC

fu

nct

ion

s ar

e d

ire

cte

d

and

eva

luat

ed

by

the

h

igh

est

leve

l of

the

o

rgan

izat

ion

. G

oa

ls a

re m

on

ito

red

an

d e

valu

ate

d a

t le

ast

on

ce a

ye

ar

by

th

e

ho

spit

al

ma

na

ge

me

nt.

Min

ute

s, r

ep

ort

s, o

r

an

nu

al

rep

ort

.

IPC

Ed

uca

tio

n

The

IPC

pro

gram

is

con

sid

ere

d t

o b

e a

n

inte

gral

par

t o

f w

ork

by

all

pe

rso

nn

el.

Th

ere

is

an

ori

en

tati

on

pro

gra

m* f

or

ne

w p

ers

on

ne

l a

nd

th

is

pro

gra

m i

s im

ple

me

nte

d.

Wri

tte

n p

rog

ram

th

at

incl

ud

es

IPC

sta

nd

ard

s.

Re

po

rt o

n c

om

pli

an

ce

wit

h t

he

pro

gra

m.

*

See Glossary.

Page 17: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

1

AR

EA: E

PID

EMIO

LOG

ICA

L SU

RV

EILL

AN

CE

OF

INFE

CTI

ON

S

Co

mp

on

en

ts

Ch

arac

teri

stic

s

Ind

icat

or

Su

gge

ste

d v

eri

fie

r

Pre

sen

t?

Ph

ysi

cia

n t

rain

ed

in

ba

sic

ep

ide

mio

log

y a

nd

IP

C

Inte

rvie

w,

cert

ific

ate

s

Th

e p

rogr

am h

as a

p

hys

icia

n f

or

the

ac

tivi

tie

s.

# o

f p

hy

sici

an

s:

T

ota

l ho

urs

pe

r w

ee

k:

Inte

rvie

w1

Nu

rsin

g p

rofe

ssio

na

l tr

ain

ed

in

ep

ide

mio

log

ica

l su

rve

illa

nce

, IP

C,

an

d

sup

erv

isio

n

Inte

rvie

w,

cert

ific

ate

s

The

pro

gram

has

a

nu

rsin

g p

rofe

ssio

nal

fo

r H

AI c

on

tro

l.

# o

f n

urs

ing

pro

fess

ion

als

:

To

tal

ho

urs

pe

r w

ee

k:

Inte

rvie

w2

Pe

rso

nn

el

Mic

rob

iolo

gist

A

cce

ss* t

o p

rofe

ssio

na

l m

icro

bio

log

ist

In

terv

iew

Sta

nd

ard

ize

d d

efi

nit

ion

s o

f m

ost

fre

qu

en

t in

fect

ion

s

Loca

l d

ocu

me

nt

At

lea

st

we

ek

ly

case

-fin

din

g

in

risk

g

rou

ps,

b

y

revi

ew

o

f cl

inic

al

his

tori

es

an

d l

ab

ora

tory

da

ta

Su

rve

illa

nce

re

cord

she

ets

, in

terv

iew

Ca

se-f

ind

ing

ca

rrie

d o

ut

by

pro

fess

ion

als

In

terv

iew

Surv

eill

ance

is c

on

du

cte

d

wit

h a

ctiv

e d

ata

colle

ctio

n m

eth

od

s

Sta

nd

ard

ize

d d

efi

nit

ion

s o

f e

xpo

sed

in

div

idu

als

(d

en

om

ina

tors

of

rate

s) a

nd

of

ho

w i

nfo

rma

tio

n o

n s

uch

in

div

idu

als

is

coll

ect

ed

Loca

l p

roce

du

re a

nd

inte

rvie

w

Ha

s m

on

thly

HA

I ra

tes

for

ea

ch b

asi

c in

dic

ato

r*3

Nu

mb

er

of

mo

nth

s In

th

e l

ast

ye

ar

the

in

dic

ato

r w

as

pro

vid

ed

:

Re

po

rts

An

nu

al

an

aly

sis

an

d r

ep

ort

on

an

tim

icro

bia

l d

rug

re

sist

an

ce

Re

po

rt

An

nu

al

an

aly

sis

of

HA

I tr

en

ds

tha

t id

en

tifi

es

pro

ble

ms

an

d p

rop

ose

s

solu

tio

ns

R

ep

ort

Eva

lua

tio

n s

yst

em

(e

. g

., p

rev

ale

nce

) o

f th

e c

ap

aci

ty o

f th

e

surv

eil

lan

ce s

yst

em

to

de

tect

in

fect

ion

s

Eva

lua

tio

n r

ep

ort

Surv

eill

ance

m

eth

od

Ep

ide

mio

logi

cal

info

rmat

ion

is a

nal

yze

d

to d

ete

ct H

AI p

rob

lem

s an

d e

valu

ate

th

e im

pac

t o

f in

terv

en

tio

ns

Id

en

tifi

es

ep

ide

mic

ou

tbre

ak

s a

nd

ha

s o

utb

rea

k r

ep

ort

Nu

mb

er

of

ou

tbre

ak

s in

th

e l

ast

ye

ar?

Ave

rag

e t

ime

fo

r d

ete

ctio

n o

f o

utb

rea

ks:

Ou

tbre

ak

re

po

rt

Pe

rio

dic

re

po

rt w

ith

an

aly

sis,

re

com

me

nd

ati

on

s, a

nd

kn

ow

n

dis

trib

uti

on

Re

po

rt o

r b

ull

eti

ns

an

d l

ist

of

dis

trib

uti

on

Dis

sem

inat

ion

of

info

rmat

ion

Info

rmat

ion

is

dis

sem

inat

ed

to

all

wh

o

ne

ed

it

Up

-to

-da

te i

nfo

rma

tio

n i

s a

vail

ab

le a

nd

kn

ow

n i

n a

ll t

he

de

pa

rtm

en

ts

invo

lve

d i

n s

urv

eil

lan

ce

Inte

rvie

w m

an

ag

ers

*

See Glossary.

1- minimum of 10 or more hours a week – Core components for infection prevention and control programmes WHO/HSE/EPR/2009

2- minimum of one full-time professional per 250 beds - Haley RW et al. Am J Epidemiol. 1985 Feb; 121(2):182-205.

3- minimum of at least 80% of the year

Page 18: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

1

AR

EA: M

ICR

OB

IOLO

GY

Co

mp

on

en

ts

Ch

arac

teri

stic

s

Ind

icat

or

Su

gge

st V

eri

fie

r

Pre

sen

t?

Ide

nti

fica

tio

n o

f a

ero

bic

ba

cte

ria

to

sp

eci

es

leve

l in

blo

od

cu

ltu

res

En

tero

cocc

us

fae

ciu

m a

nd

En

tero

cocc

us

fae

cali

s

Pse

ud

om

on

as

ae

rug

ino

sa

Sta

ph

ylo

cocc

us

au

reu

s

En

tero

ba

cte

ria

cea

e

Re

po

rt,

reco

rd,

an

d

lab

ora

tory

in

terv

iew

Ide

nti

fica

tio

n o

f vi

ral

ag

en

ts:

He

pa

titi

s B

an

d C

HIV

Ad

en

ovi

rus

Infl

ue

nza

Sy

ncy

tia

l re

spir

ato

ry v

iru

s

Ro

tavi

rus

Re

po

rt,

reco

rd,

an

d

lab

ora

tory

in

terv

iew

Ide

nti

fica

tio

n o

f M

. tu

be

rcu

losi

s

Re

po

rt,

reco

rd,

an

d

lab

ora

tory

in

terv

iew

Ide

nti

fica

tio

n o

f C

an

did

a

Re

po

rt,

reco

rd,

an

d

lab

ora

tory

in

terv

iew

The

est

ablis

hm

en

t h

as

acce

ss* t

o id

en

tifi

cati

on

of

the

mo

st r

ele

van

t m

icro

bia

l ag

en

ts in

HA

I

De

term

ina

tio

n o

f C

lost

rud

iun

dif

fici

le

Re

po

rt,

reco

rd,

an

d

lab

ora

tory

in

terv

iew

Ide

nti

fy s

usc

ep

tib

ilit

y p

att

ern

s fo

r th

e m

ost

fre

qu

en

t a

ge

nts

or

tho

se o

f e

pid

em

iolo

gic

al

imp

ort

an

ce f

or

HA

I

Me

thic

illi

n-r

esi

sta

nt

Sta

ph

ylo

cocc

us

au

reu

s

Va

nco

my

cin

-re

sist

an

t S

tap

hylo

cocc

us

au

reu

s, w

ith

CIM

Re

po

rt,

reco

rd,

an

d

lab

ora

tory

in

terv

iew

Dia

gno

stic

ca

pab

ility

Va

nco

my

cin

-re

sist

an

t E

nte

roco

ccu

s.

Re

po

rt,

reco

rd,

an

d

lab

ora

tory

in

terv

iew

En

tero

ba

cte

ria

an

d n

on

ferm

en

tin

g b

aci

lli

tha

t p

rod

uce

carb

ap

en

em

ase

s a

nd

ext

en

de

d-s

pe

ctru

m b

eta

-la

cta

ma

ses

(ES

BL)

Re

po

rt,

reco

rd,

an

d

lab

ora

tory

in

terv

iew

Has

ro

uti

ne

pro

ced

ure

s an

d

cap

acit

y to

ide

nti

fy

susc

ep

tib

ility

to

an

tim

icro

bia

l dru

gs o

f H

AI

age

nts

iso

late

d

No

nfe

rme

nti

ng

ba

cill

i p

rod

uct

ive

of

carb

ap

en

em

ase

s

Re

po

rt,

reco

rd,

an

d

lab

ora

tory

in

terv

iew

*

See Glossary.

Page 19: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

1

Th

e p

rog

ram

ma

inta

ins

qu

ali

ty c

on

tro

l re

cord

s o

n i

de

nti

fica

tio

n

of

ag

en

ts a

nd

an

tim

icro

bia

l su

sce

pti

bil

itie

s in

acc

ord

an

ce w

ith

NC

CLS

or

oth

er

sta

nd

ard

s

Re

po

rt,

reco

rd,

an

d

lab

ora

tory

in

terv

iew

Th

e p

rog

ram

is

sub

mit

ted

to

an

ext

ern

al

pe

rfo

rma

nce

eva

lua

tio

n

pro

gra

m a

t le

ast

on

ce a

ye

ar

Re

po

rt f

rom

refe

ren

ce l

ab

ora

tory

Q

ual

ity

con

tro

l

Mic

rob

iolo

gy a

ctiv

itie

s ar

e

eva

luat

ed

pe

rio

dic

ally

wit

h

inte

rnal

an

d e

xte

rnal

q

ual

ity

con

tro

l T

he

re i

s a

ma

nu

al

of

pro

ced

ure

s fo

r in

tern

al

qu

ali

ty c

on

tro

l,

up

da

ted

at

lea

st e

very

3 y

ea

rs,

wh

ich

is

dis

sem

ina

ted

to

th

e

pe

rso

nn

el

co

nfi

rm

Th

ere

is

a s

pe

cim

en

co

lle

ctio

n a

nd

sh

ipp

ing

ma

nu

al,

up

da

ted

at

lea

st e

very

3 y

ea

rs,

wh

ich

is

dis

sem

ina

ted

to

th

e p

ers

on

ne

l

co

nfi

rm

Sp

eci

me

n

colle

ctio

n,

pro

cess

ing,

an

d

ship

pin

g st

and

ard

s

The

re a

re s

tan

dar

diz

ed

te

chn

iqu

es

and

pro

ced

ure

s

Th

ere

exi

sts

a s

pe

cim

en

pro

cess

ing

ma

nu

al,

up

da

ted

at

lea

st

ev

ery

3 y

ea

rs,

wh

ich

is

dis

sem

ina

ted

to

th

e p

ers

on

ne

l

co

nfi

rm

Pe

rio

dic

re

po

rt o

n t

he

ag

en

ts r

esp

on

sib

le f

or

HA

I b

y s

pe

cim

en

typ

e a

nd

th

e d

ep

art

me

nt

of

ori

gin

Ho

w m

an

y i

n a

ye

ar?

Mic

rob

iolo

gy

re

po

rt

Pe

rio

dic

re

po

rt o

n a

nti

mic

rob

ial

susc

ep

tib

ilit

y p

att

ern

s fo

r

rele

van

t e

tio

log

ic a

ge

nts

Ho

w m

an

y i

n a

ye

ar?

Mic

rob

iolo

gy

re

po

rt

an

d r

eco

rd

M

icro

bio

logi

cal

info

rmat

ion

C

linic

al i

nfo

rmat

ion

an

alys

is

Th

ere

is

an

ale

rt m

ech

an

ism

fo

r u

nu

sua

l m

icro

bio

log

ica

l fi

nd

ing

s

Re

po

rt a

nd

re

cord

s

A l

ab

ora

tory

sta

ff m

em

be

r is

pa

rt o

f th

e H

AI

con

tro

l co

mm

itte

e o

f

con

tro

ls

Re

cord

s

P

arti

cip

atio

n in

th

e c

om

mit

tee

fo

r H

AI p

reve

nti

on

an

d c

on

tro

l

Re

lati

on

of

the

m

icro

bio

logi

st t

o t

he

HA

I co

ntr

ol c

om

mit

tee

P

art

icip

ati

on

of

the

la

bo

rato

ry i

n t

he

pre

pa

rati

on

of

ma

nu

als

an

d

gu

ide

lin

es

of

the

HA

I co

mm

itte

e

Co

nfi

rm

Page 20: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

2

AR

EA: I

NTE

RV

ENTI

ON

STR

ATE

GIE

S

Co

mp

on

en

t

Ch

arac

teri

stic

s

Ind

icat

or

Su

gge

ste

d v

eri

fie

r

Co

nso

lidat

ed

ac

tivi

tie

s1 P

rese

nt?

Exi

ste

nce

of

a c

om

ple

te r

eg

ula

tory

te

chn

ica

l b

asi

s

Sta

nd

ard

s*,

gu

ide

s* o

r

ma

nu

als

*

Su

mm

ary

co

lum

n (

a)

Th

e r

eg

ula

tio

ns

ha

ve b

ee

n u

pd

ate

d w

ith

in t

he

la

st

thre

e y

ea

rs

Sta

nd

ard

s *

, g

uid

es

*

or

ma

nu

als

*

Su

mm

ary

co

lum

n (

b)

Pri

nci

pal

act

ivit

ies

for

IPC

ar

e r

egu

late

d in

ac

cord

ance

wit

h b

est

cu

rre

nt

kn

ow

led

ge

Th

e c

on

ten

ts a

nd

in

dic

ato

rs o

f th

e t

ech

nic

al

reg

ula

tio

ns

are

evi

de

nce

-ba

sed

Sta

nd

ard

s *

, g

uid

es

*

or

ma

nu

als

*

Su

mm

ary

co

lum

n (

c)

Th

e r

eg

ula

tio

ns

ha

ve b

ee

n d

isse

min

ate

d w

ith

eff

ect

ive

act

ivit

ies

to t

ho

se p

ers

on

ne

l w

ho

sh

ou

ld

be

fa

mil

iar

wit

h t

he

m

Tra

inin

g p

rog

ram

eva

lua

ted

, a

tte

nd

an

ce

rep

ort

s

Su

mm

ary

co

lum

n (

d)

Su

pe

rvis

ion

* o

f co

mp

lia

nce

wit

h t

he

re

gu

lati

on

s b

y

pe

rso

nn

el

Su

pe

rvis

ion

re

po

rts

S

um

ma

ry c

olu

mn

(e

)

Inte

rve

nti

on

s to

im

pro

ve H

AI

pre

ven

tio

n a

nd

co

ntr

ol

Co

mp

lian

ce w

ith

re

gula

tio

ns

is p

rom

ote

d

and

eva

luat

ed

Th

ere

is

evi

de

nce

of

com

pli

an

ce w

ith

th

e b

asi

c

reg

ula

tio

ns

Dir

ect

ob

serv

ati

on

S

um

ma

ry c

olu

mn

(f)

1

Use the “PREVENTION AND CONTROL STRATEGIES RECORD FORM” to record the detailed information consolidated here.

*

See Glossary.

Page 21: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

2

PR

EVEN

TIO

N A

ND

CO

NTR

OL

STR

ATE

GIE

S R

ECO

RD

FO

RM

C

ha

ract

eri

stic

s

Infe

ctio

n p

rev

en

tio

n

act

ivit

ies

(a)

Pre

sen

t

(b)

Up

da

ted

(< 3

ye

ars

)

Evi

de

nce

-ba

sed

2 c

en

tra

l co

nce

pts

(c)

Are

th

ese

con

cep

ts i

ncl

ud

ed

in t

he

sta

nd

ard

?

(d

)

Dis

sem

ina

te

d t

o

pe

rso

nn

el

(e)

Su

pe

rvis

ion

pla

n f

or

the

sta

nd

ard

ap

pli

ed

(f)

Co

mp

lia

n

ce w

ith

the

sta

nd

ard

Pre

ve

nti

on

of

ba

cte

rem

ia a

sso

cia

ted

wit

h c

en

tra

l v

en

ou

s

cath

ete

r

Ma

xim

um

ba

rrie

rs (

surg

ica

l p

rep

ara

tio

n o

f p

ati

en

t a

nd

ph

ysi

cia

n)

for

its

inst

all

ati

on

Cir

cuit

ha

nd

lin

g w

ith

ase

pti

c te

chn

iqu

e

Use

of

chlo

rhe

xid

ine

fo

r m

ain

ten

an

ce o

f t

he

sit

e o

f

inse

rtio

n

Pre

ve

nti

on

of

pn

eu

mo

nia

ass

oci

ate

d

wit

h m

ech

an

ica

l

ven

tila

tio

n

Clo

sed

asp

ira

tio

n o

r w

ith

aid

of

secr

eti

on

s

Ha

nd

lin

g o

f ci

rcu

its

wit

h a

sep

tic

tech

niq

ue

Cir

cuit

s ch

an

ge

be

twe

en

pa

tie

nts

Use

of

circ

uit

s w

ith

at

lea

st h

igh

-le

vel

dis

infe

ctio

n

Se

mi-

recl

inin

g p

osi

tio

n

Ora

l h

yg

ien

e

Pre

ve

nti

on

of

uri

na

ry

infe

ctio

n a

sso

cia

ted

wit

h u

rin

ary

ca

the

ter

Cir

cuit

pe

rma

ne

ntl

y c

lose

d

Ba

g e

mp

tie

d a

nd

ha

nd

s w

ash

ed

be

twe

en

pa

tie

nts

Co

lle

ctio

n b

ag

pe

rma

ne

ntl

y b

elo

w b

lad

de

r le

vel

Pre

ve

nti

on

of

surg

ica

l

wo

un

d i

nfe

ctio

ns

Infe

ctio

us

foci

eli

min

ate

d b

efo

re s

urg

ery

Su

rgic

al

site

no

t sh

ave

d w

ith

ra

zor

bla

de

An

tim

icro

bia

l p

rop

hy

laxi

s is

ad

min

iste

red

wit

hin

a

ho

ur

be

fore

th

e s

urg

ica

l in

cisi

on

Sta

nd

ard

pre

cau

tio

ns

an

d a

dd

itio

na

l

pre

cau

tio

ns

Use

of

glo

ves

for

ha

nd

lin

g s

ecr

eti

on

s

Ha

nd

-wa

shin

g b

efo

re a

nd

aft

er

pa

tie

nt

care

Use

PP

E (

for

exa

mp

le,

glo

ves,

go

wn

, m

ask

s),

ap

pro

pri

ate

fo

r th

e l

ev

el

of

exp

ect

ed

co

nta

min

ati

on

wh

en

pa

tie

nt

is t

rea

ted

in

iso

lati

on

Ase

pti

c te

chn

iqu

e

Ha

nd

-wa

shin

g b

efo

re a

nd

aft

er

pa

tie

nt

care

Use

of

an

tise

pti

cs f

or

skin

pre

pa

rati

on

be

fore

in

vasi

ve

pro

ced

ure

s

Use

of

ste

rile

ma

teri

al

in i

nva

sive

pro

ced

ure

s

Re

stri

cte

d-u

se

an

tib

ioti

cs

Va

nco

my

cin

Th

ird

-ge

ne

rati

on

ce

ph

alo

spo

rin

of

3ra

ge

ne

rati

on

.

Oth

ers

?

Sp

eci

fy w

hic

h:

2

These concepts are based on well-designed studies that permit the conclusion that compliance is effective in preventing infection

Page 22: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

2

AR

EA: S

TER

ILIZ

ATI

ON

AN

D H

IGH

-LEV

EL D

ISIN

FEC

TIO

N

Co

mp

on

en

ts

Ch

arac

teri

stic

s

Ind

icat

or

Su

gge

ste

d v

eri

fie

r

Pre

sen

t?

Ap

pro

pri

ate

me

tho

ds

On

ly s

teri

liza

tio

n m

eth

od

s o

f p

rove

n e

ffic

acy

are

use

d3

Inte

rvie

w,

sta

nd

ard

s,

dir

ect

ob

serv

ati

on

Stan

dar

diz

ed

pro

ced

ure

s

Sta

nd

ard

s a

nd

pro

ced

ure

s h

ave

be

en

est

ab

lish

ed

fo

r a

ll p

roce

sse

s

rela

ted

to

ste

rili

zati

on

Sta

nd

ard

s a

nd

pro

ced

ure

s m

an

ua

l

Use

of

ind

ivid

ua

l ch

em

ica

l in

dic

ato

rs i

n e

ach

pa

cka

ge

D

ire

ct o

bse

rva

tio

n

Use

of

bio

log

ica

l in

dic

ato

rs a

t le

ast

fo

r im

pla

nts

an

d a

fte

r

eq

uip

me

nt

rep

air

R

eco

rd

Da

ily

use

of

Bo

wie

-Dic

k t

est

fo

r p

re v

acu

um

au

tocl

av

es

R

eco

rds

Su

rgic

al

inst

rum

en

ts p

roce

sse

d a

re f

ree

fro

m o

rga

nic

ma

tte

r

Dir

ect

ob

serv

ati

on

All

pa

cka

ge

s a

re l

ab

ele

d w

ith

exp

ira

tio

n d

ate

s a

nd

are

wit

hin

th

e

eff

ect

ive

pe

rio

d

Dir

ect

ob

serv

ati

on

Un

da

ma

ge

d c

on

tain

ers

th

at

are

ap

pro

pri

ate

fo

r th

e m

eth

od

4

Dir

ect

ob

serv

ati

on

Ste

riliz

atio

n p

roce

sse

s co

ntr

olle

d t

o g

uar

ante

e

resu

lts

Use

Fla

sh a

uto

cla

ve

on

ly i

n e

me

rge

nci

es

R

eco

rds

Ste

riliz

atio

n*

me

tho

ds

Pro

cess

es

are

pe

rfo

rmed

o

n o

per

atio

nal

eq

uip

me

nt

Th

ere

is

a p

rog

ram

fo

r p

rev

en

tive

ma

inte

na

nce

of

the

ste

rili

zati

on

eq

uip

me

nt

Ma

inte

na

nce

pro

gra

ms

reco

rds

Ap

pro

pri

ate

met

ho

ds

O

nly

hig

h-l

ev

el

dis

infe

ctio

n o

f m

eth

od

s o

f p

rov

en

eff

ica

cy5 a

re

use

d

Inte

rvie

w,

sta

nd

ard

s,

an

d d

ire

ct o

bse

rva

tio

n.

Sta

nd

ard

s a

nd

pro

ced

ure

s a

re e

sta

bli

she

d f

or

all

pro

cess

es

rela

ted

to

dis

infe

ctio

n

Sta

nd

ard

s a

nd

pro

ced

ure

s m

an

ua

ls

Ap

pro

pri

ate

exp

osu

re t

ime

is

con

tro

lle

d i

n e

ve

ry c

ycl

e

Sta

nd

ard

s a

nd

re

cord

s

Hig

h-l

eve

l d

isin

fect

ion

*

me

tho

ds

H

igh

-le

vel d

isin

fect

ion

p

roce

sse

s c

on

tro

lled

to

gu

aran

tee

re

sult

s

Ch

em

ica

l in

dic

ato

r o

f co

nce

ntr

ati

on

at

lea

st d

ail

y

Re

cord

s

*

See Glossary.

3 As of the date this document was prepared: autoclaves, dry heat, ethylene oxide in automated equipment, formaldehyde in automated equipment, hydrogen perxoide

plasma in automated equipment, peracetic acid in auomated equipment.

4

Fenstrated boxes for use in autoclaves, use of memory-free paper for all paper packaging, cellulose-free packaging for plasma sterilization

5 As of the date this document was prepared, : 2% glutaraldehyde, peracetic acid, orthophthalaldehyde (OPA). For dialysis filters 4% formaldehyde can be used

Page 23: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

2

AR

EA: P

ERSO

NN

EL H

EALT

H

Co

mp

on

en

ts

Ch

arac

teri

stic

s

Ind

icat

or

Su

gge

ste

d v

eri

fie

r

Pre

sen

t?

Sta

ff t

rain

ing

on

pre

ve

nti

on

of

exp

osu

re t

o s

ha

rps

an

d o

n

imm

un

iza

tio

n

Pro

gra

m a

nd

ca

re r

eco

rds

Pro

gra

m *

in

wri

tin

g f

or

He

pa

titi

s B

im

mu

niz

ati

on

of

pe

rso

nn

el

exp

ose

d t

o b

loo

d

Pro

gra

m

He

pa

titi

s B

pro

gra

m c

ove

rag

e *

g

rea

ter

tha

n o

r

eq

ua

l to

80

% o

f th

e t

arg

et

po

pu

lati

on

R

eco

rds

an

d c

ov

era

ge

Pro

gra

m *

in

wri

tin

g f

or

an

nu

al

infl

ue

nza

imm

un

iza

tio

n f

or

all

he

alt

h

sta

ff

Pro

gra

m

Infl

ue

nza

pro

gra

m c

ov

era

ge

* g

rea

ter

tha

n o

r

eq

ua

l to

80

% o

f th

e t

arg

et

po

pu

lati

on

R

eco

rds

an

d c

ov

era

ge

Pro

gra

m *

in

wri

tin

g f

or

rub

ell

a i

mm

un

iza

tio

n f

or

wo

me

n a

nd

su

sce

pti

ble

me

n

Pro

gra

m

Imm

un

iza

tio

n*

pro

gra

m

Ru

be

lla

pro

gra

m c

ove

rag

e *

gre

ate

r th

an

or

eq

ua

l

to 8

0%

of

the

ta

rge

t p

op

ula

tio

n

Re

cord

s a

nd

co

ve

rag

e

The

re

are

acti

viti

es

for

pre

ven

tio

n

of

infe

ctio

ns

that

ca

n

be

tr

ansm

itte

d

be

twe

en

h

eal

th

wo

rke

rs

and

pat

ien

ts

Ma

na

ge

me

nt

of

exp

osu

res

to b

loo

d c

au

sed

by

in

juri

es

fro

m s

ha

rp

ob

ject

s u

sed

wit

h p

ati

en

ts

Sta

nd

ard

an

d r

eco

rds

Ma

na

ge

me

nt

of

pe

rso

nn

el

wit

h c

om

mu

nic

ab

le6 i

nfe

ctio

ns

tha

t is

sup

erv

ise

d*

an

d c

om

pli

ed

wit

h

Sta

nd

ard

an

d r

eco

rds

Pre

ven

tio

n o

f in

fect

ion

s th

at

can

be

tr

ansm

itte

d

be

twe

en

he

alth

w

ork

ers

an

d

pat

ien

ts

Pe

rso

nn

el i

nfe

ctio

ns

are

m

on

ito

red

an

d m

eas

ure

s ta

ken

to

pro

tect

exp

ose

d

pe

rso

nn

el a

nd

pat

ien

ts

Ma

na

ge

me

nt

of

exp

osu

res

of

mu

cou

s m

em

bra

ne

to

blo

od

an

d

org

an

ic f

luid

s a

nd

to

in

juri

es

fro

m s

ha

rp o

bje

cts

use

d w

ith

pa

tie

nts

S

tan

da

rd a

nd

re

cord

s

* See Glossary.

6 Establish whether personnel with infectious communicable diseases may be in contact with patients or whether they should be absent from work during the course of the

infection

Page 24: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

2

AR

EA: H

OSP

ITA

L EN

VIR

ON

MEN

T A

ND

SA

NIT

ATI

ON

Co

mp

on

en

ts

Ch

arac

teri

stic

s

Ind

icat

or

Su

gge

ste

d

veri

fie

r

Pre

sen

t?

Po

tab

le w

ate

r is

ava

ila

ble

on

an

on

go

ing

ba

sis

wit

h a

min

imu

m

of

eig

ht

ho

urs

su

pp

ly

Dir

ect

ob

serv

ati

on

Acc

ess

ible

7 a

nd

op

era

tio

na

l w

ash

ba

sin

s w

ith

so

ap

an

d s

up

pli

es

for

dry

ing

ha

nd

s in

all

pa

tie

nt

care

are

as

Gly

ceri

na

ted

alc

oh

ol

in a

ll p

ati

en

t ca

re a

rea

s

Dir

ect

ob

serv

ati

on

Ha

nd

-

wa

shin

g

Op

era

tio

na

l w

ash

ba

sin

s w

ith

acc

ess

ible

su

pp

lie

s in

all

dru

g

pre

pa

rati

on

an

d i

nva

sive

pro

ced

ure

s a

rea

s

Dir

ect

ob

serv

ati

on

Se

pa

rati

on

of

a m

ete

r o

r m

ore

be

twe

en

be

ds

in p

ed

iatr

ics

D

ire

ct

ob

serv

ati

on

Min

imu

m

spa

ce

Se

pa

rati

on

of

a m

ete

r o

r m

ore

be

twe

en

be

ds

in i

nte

nsi

ve

ca

re

un

its

Dir

ect

ob

serv

ati

on

Bas

ic s

tru

ctu

ral c

on

dit

ion

s fo

r in

fect

ion

pre

ven

tio

n

exi

st

Pa

rtic

ipa

tio

n b

y I

PC

te

am

if

rem

od

eli

ng

or

con

stru

ctio

n t

ak

es

pla

ce i

n a

rea

s

wh

ere

act

ivit

ies

of

clin

ica

l im

po

rta

nce

are

co

nd

uct

ed

Min

ute

s, a

nd

inte

rvie

ws.

Ava

ila

bil

ity

of

roo

m f

or

iso

lati

on

of

ind

ivid

ua

l p

ati

en

ts o

r g

rou

ps,

wit

h

op

era

tio

na

l w

ash

ba

sin

s, a

cce

ss t

o g

lyce

rin

ate

d a

lco

ho

l so

luti

on

, su

pp

lie

s,

clo

sed

do

ors

, a

nd

pe

rso

na

l p

rote

ctio

n e

qu

ipm

en

t

Dir

ect

ob

serv

ati

on

Fo

r p

ati

en

ts w

ho

ne

ed

re

spir

ato

ry i

sola

tio

n,

roo

ms

are

ava

ila

ble

fo

r is

ola

tio

n o

f

ind

ivid

ua

l o

r g

rou

ps,

wit

h o

pe

rati

on

al

wa

shb

asi

ns,

acc

ess

to

gly

ceri

na

ted

alc

oh

ol

solu

tio

n,

sup

pli

es,

clo

sed

do

ors

, a

nd

pe

rso

na

l p

rote

ctio

n e

qu

ipm

en

t.

Th

e i

sola

tio

n r

oo

ms

ha

ve

air

ve

nts

to

th

e o

uts

ide

Dir

ect

ob

serv

ati

on

Are

as

for

iso

lati

on

an

d p

ati

en

ts i

n i

sola

tio

n a

re m

ark

ed

D

ire

ct

ob

serv

ati

on

Ph

ysic

al p

lan

t co

nd

itio

ns.

Co

nd

itio

ns

exi

st f

or

ind

ivid

ual

iso

lati

on

of

pat

ien

ts

Th

ere

is

a s

pa

ce r

ese

rve

d f

or

pro

ced

ure

s th

at

ge

ne

rate

a

ero

sols

D

ire

ct

ob

serv

ati

on

San

itat

ion

co

nd

itio

ns

Sh

arp

s ar

e h

and

led

in a

su

ch a

way

as

to p

reve

nt

Dis

po

sal

in w

ate

rpro

of,

pu

nct

ure

-re

sist

an

t co

nta

ine

rs

Dir

ect

ob

serv

ati

on

7

Washbasins should be inside the patients' hospital rooms

Page 25: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

2

Th

e c

on

tain

ers

fo

r sh

arp

s a

re i

n a

sa

fe p

lace

ad

eq

ua

te f

or

gu

ara

nte

ein

g t

he

safe

ty o

f p

ati

en

ts a

nd

he

alt

h w

ork

ers

Dir

ect

ob

serv

ati

on

ac

cid

en

ts

Pe

rso

nn

el

ha

nd

lin

g w

ast

e u

se p

rote

ctiv

e8 b

arr

iers

Dir

ect

ob

serv

ati

on

an

d i

nte

rvie

w.

8

Thick waterproof gloves, eye covers if splashing may occur during activities

Page 26: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

2

AR

EA: I

NEF

FEC

TIV

E P

RA

CTI

CES

The

fo

llow

ing

pra

ctic

es

ha

ve b

ee

n u

sed

in

th

e p

ast

for

pre

ven

tio

n o

f in

fect

ion

s. T

he

re a

re c

urr

en

tly

are

no

bas

es

for

reco

mm

end

ing

the

ir c

on

tin

uat

ion

. P

rese

nt?

Pro

cess

ing

wit

h d

isin

fect

an

ts t

ha

t d

o n

ot

ha

ve p

rove

n e

ffic

acy

fo

r st

eri

liza

tio

n o

r h

igh

-le

vel

dis

infe

ctio

n

Sy

rin

ge

s o

r n

ee

dle

s th

at

are

use

d o

n m

ore

th

an

on

e p

ati

en

t (e

. g

., i

n a

ne

sth

esi

a o

r in

ne

on

ato

log

y)

Use

of

Fla

sh s

teri

liza

tio

n a

s a

ro

uti

ne

me

tho

d t

o s

teri

lize

in

stru

me

nts

Sh

avi

ng

su

rgic

al

site

wit

h r

azo

r b

lad

e

Use

im

me

rsio

n i

n c

he

mic

al

ag

en

ts f

or

ste

rili

zati

on

En

viro

nm

en

tal

dis

infe

ctio

n w

ith

fo

rma

lde

hy

de

Ste

rili

zati

on

wit

h f

orm

ald

eh

yd

e t

ab

lets

Ste

rili

zati

on

of

ma

teri

als

in

pla

stic

ba

gs

an

d e

thy

len

e o

xid

e a

mp

ou

les

Re

cycl

ing

of

dis

po

sab

le p

eri

ph

era

l v

en

ou

s in

fusi

on

ma

teri

al

Use

of

air

co

nd

itio

nin

g w

ith

ou

t fi

lte

r in

op

era

tin

g r

oo

m

Use

of

inse

cure

bo

xes

for

dis

po

sal

of

sha

rps

Cri

tica

l a

rea

s fo

r p

ati

en

t ca

re,

inva

sive

pro

ced

ure

s, a

nd

pre

pa

rati

on

of

me

dic

ati

on

s sh

ou

ld n

ot

ha

ve v

en

tila

tors

Kn

ow

n t

o b

e

ine

ffe

ctiv

e

pra

ctic

es

th

at

incr

eas

e r

isk9 .

Ch

em

ica

l d

eco

nta

min

ati

on

of

con

tam

ina

ted

ma

teri

al

Ro

uti

ne

cu

ltu

res

for

pe

rso

nn

el

wh

o a

re c

arr

iers

11

Use

of

top

ica

l a

nti

sep

tic

on

op

en

wo

un

ds

Co

nti

nu

ati

on

of

an

tib

ioti

c tr

ea

tme

nt

aft

er

the

op

era

tio

n e

nd

s

Ro

uti

ne

cu

ltu

res

of

vasc

ula

r ca

the

ter

tip

s

Kn

ow

n t

o b

e

ine

ffe

ctiv

e a

nd

exp

en

sive

pra

ctic

es.

10

Dis

infe

ctio

n o

f h

osp

ita

l w

ast

e (

exc

ep

t fo

r m

icro

bio

log

y l

ab

ora

tory

)

9 These concepts are based on well-designed studies that lead to the conclusion that they do not prevent infection and, to the contraary, may increase the risk of infection.

10 These concepts are based on well-designed studies that lead to the conclusion that they do not prevent infection. Although they do not increase risk, they often cause

unnecessary expense.

11 These practices are not useful unless there is an epidemic in which there is reason to consider the existence of carriers as a risk factor.

Page 27: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

2

Use

of

foo

twe

ar

cove

rs i

n a

ll a

rea

s o

f th

e h

osp

ita

l

Ro

uti

ne

cu

ltu

res

of

uri

na

ry c

ath

ete

r ti

ps

Ro

uti

ne

en

viro

nm

en

tal

cult

ure

s (e

. g

., a

ir,

surf

ace

s, o

r so

ap

)

Page 28: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

2

AR

EA: N

EON

ATO

LOG

Y

Co

mp

on

en

ts

Ch

arac

teri

stic

s

Ind

icat

or

Su

gge

ste

d v

eri

fie

r

Pre

sen

t?

Nu

mb

er

of

nu

rsin

g p

rofe

ssio

na

ls

Are

th

ere

su

ffic

ien

t n

urs

ing

pro

fess

ion

als

, d

ep

en

din

g o

n t

he

seve

rity

of

the

ch

ild

ren

's i

lln

ess

es?

Inte

rvie

w

Acc

ess

ible

an

d o

pe

rati

on

al

wa

shb

asi

ns

wit

h s

oa

p a

nd

su

pp

lie

s

for

dry

ing

of

ha

nd

s in

all

th

e p

ati

en

t

care

are

as

Dir

ect

ob

serv

ati

on

Gly

ceri

na

ted

alc

oh

ol

in a

ll t

he

pa

tie

nt-

care

are

as

Dir

ect

ob

serv

ati

on

Ha

nd

-w

ash

ing

O

pe

rati

on

al

wa

shb

asi

ns

wit

h

acc

ess

ible

su

pp

lie

s in

all

are

as

for

pre

pa

rati

on

or

dru

gs

an

d f

orm

ula

s

an

d f

or

inva

siv

e p

roce

du

res

Dir

ect

ob

serv

ati

on

The

re

are

b

asic

ge

ne

ral

stru

ctu

ral

con

dit

ion

s fo

r

pre

ven

tio

n

of

in

fect

ion

s

Min

imu

m s

pa

ce

Se

pa

rati

on

of

a m

ete

r o

r m

ore

be

twe

en

cra

dle

s in

ne

on

ato

log

y

Dir

ect

ob

serv

ati

on

Use

of

ase

pti

c te

chn

iqu

e f

or

inse

rtio

n

Inte

rvie

w,

sta

nd

ard

s,

an

d d

ire

ct o

bse

rva

tio

n.

Use

of

chlo

rhe

xid

ine

fo

r ca

re o

f th

e

inse

rtio

n p

oin

t.

Inte

rvie

w,

sta

nd

ard

s,

an

d d

ire

ct o

bse

rva

tio

n.

P

rev

en

tio

n o

f b

act

ere

mia

ass

oci

ate

d w

ith

cen

tra

l ve

no

us

cath

ete

r

Wit

hd

raw

al

of

CV

Cs

wit

h p

osi

tive

he

mo

cult

ure

s

Inte

rvie

w,

sta

nd

ard

s,

an

d d

ire

ct o

bse

rva

tio

n.

Ea

rly

be

gin

nin

g o

f th

e e

nte

ral

die

t

Inte

rvie

w

Bre

ast

mil

k i

s o

ffe

red

by

mo

the

rs

on

ly t

o t

he

ir o

wn

ch

ild

ren

In

terv

iew

, st

an

da

rds

Pre

ven

tio

n o

f in

fect

ion

s th

at

can

be

tr

ansm

itte

d t

o

pat

ien

ts

The

re

are

ac

tivi

tie

s fo

r p

reve

nti

on

o

f in

fect

ion

s th

at

can

b

e

tran

smit

ted

b

etw

ee

n

pat

ien

ts

and

he

alth

wo

rker

s

En

tera

l n

utr

itio

n a

nd

bre

ast

mil

k b

an

k

Th

ere

is

ava

ila

bil

ity

of

pa

ste

uri

zed

bre

ast

mil

k

In

terv

iew

, st

an

da

rds,

an

d d

ire

ct o

bse

rva

tio

n.

Dru

g m

an

ag

em

en

t

Th

ere

is

a p

roto

col

for

dru

g

fra

ctio

na

tio

n

Sta

nd

ard

s

Page 29: RRAAPPIIDD EEVVAALLUUAATTIIOONN GGUUIIDDEE ......Silvia Acosta de Gnass, Maria Paz Ade, Laura Araya, Maria Isabel Gonzalez Betancourt, Pola Brenner, Teresa Camou, Liliana Clara, Erna

2

All

fra

ctio

na

l d

rug

s h

av

e t

he

da

te

an

d h

ou

r o

f d

ilu

tio

n a

nd

th

e d

ate

an

d h

ou

r o

f va

lid

ity

or

exp

ira

tio

n

Inte

rvie

w,

sta

nd

ard

s,

an

d d

ire

ct o

bse

rva

tio

n.

T

he

re i

s a

pro

toco

l fo

r p

reve

nti

on

of

vert

ica

l tr

an

smis

sio

n o

f H

IV

Inte

rvie

w,

sta

nd

ard

s,

an

d d

ire

ct o

bse

rva

tio

n.

T

he

re i

s a

pro

toco

l fo

r p

reve

nti

on

of

vert

ica

l tr

an

smis

sio

n o

f H

BV

Inte

rvie

w,

sta

nd

ard

s,

an

d d

ire

ct o

bse

rva

tio

n.

Th

ere

is

a p

roto

col

for

de

colo

niz

ati

on

of

mo

the

rs

colo

niz

ed

wit

h S

tre

pto

cocc

us

B

Inte

rvie

w,

sta

nd

ard

s,

an

d d

ire

ct o

bse

rva

tio

n.

Pre

ven

tio

n o

f in

fect

ion

s th

at

can

be

tr

ansm

itte

d f

rom

m

oth

er

to c

hild

The

re a

re a

ctiv

itie

s fo

r p

reve

nti

on

of

infe

ctio

ns

that

can

b

e t

ran

smit

ted

ve

rtic

ally

C

oll

yri

um

12 is

use

d f

or

go

no

cocc

al

op

hth

alm

ia p

rop

hy

laxi

s

Inte

rvie

w,

sta

nd

ard

s,

an

d d

ire

ct o

bse

rva

tio

n.

12 1

% s

ilve

r n

itra

te o

r e

ryth

rom

yci

n o

ph

tha

lmic

oin

tme

nt