Retinopathy in Youth With Type 2Diabetes Participating in the

TODAY Clinical Trial

Featured Article:

TODAY Study Group*

Diabetes Care Volume 36: 1772-1774

June, 2013

STUDY OBJECTIVE 

• To determine the prevalence of retinopathy in 517 youth with type 2 diabetes of 2–8 years’ duration enrolled in the TODAY study

TODAY Study Group* Diabetes Care 2013;36:1772-1774

STUDY DESIGN AND METHODS

• Retinal photographs were graded centrally for retinopathy using established standards

TODAY Study Group* Diabetes Care 2013;36:1772-1774

RESULTS

• Retinopathy was identified in 13.7% of subjects

• Prevalence increased with age, diabetes duration, and mean HbA1c

• Subjects in the highest BMI tertile had the lowest prevalence of retinopathy

TODAY Study Group* Diabetes Care 2013;36:1772-1774

CONCLUSIONS

• Prevalence of retinopathy and its association with HbA1c and diabetes duration is similar to that in youth with type 1 diabetes and adults with type 2 diabetes of known duration

• Mechanism underlying the reduced risk of retinopathy in the most obese individuals is unknown

• Follow-up of this cohort will help define the natural history of retinopathy in type 2 diabetic youth

TODAY Study Group* Diabetes Care 2013;36:1772-1774

TODAY Study Group* Diabetes Care 2013;36:1772-1774