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www.lcmd.com
Reshaping
Treatment Paradigms
Corporate Presentation © Life Care Medical Devices 2017
Forward Looking Statements
This presentation contains forward-looking statements regarding our prospective performance. Forward-looking statements are based on assumptions and describe future plans, strategies, and expectations of our company. Accordingly, actual results may differ materially from anticipated results. Some of the factors that could cause our actual results to differ from our expectations include, without limitation: our ability to receive FDA and foreign regulatory approvals for our product candidates, including the LapCap2®
Laparoscopic Access Device & Life Care LCMI; risks associated with scientific research, including conducting clinical and product-related trials; the unpredictability of the size of the markets for, and market acceptance of, any of our products, including the LapCap2® Laparoscopic Access Device & Life Care LCMI; our ability to produce and sell any approved products and the price we are able realize for those products; our ability to enter into and maintain collaborations with, and our dependence on, third parties for the development and commercialization of our products, including the LapCap2®Laparoscopic Access Device & Life Care LCMI; our ability to complete future proposed acquisitions and integrate acquired products into our operations; our ability to manage our limited cash resources; our need to obtain additional funding and our ability to obtain future funding on acceptable terms; our ability to retain and hire necessary employees and to staff our operations appropriately; our ability to protect the intellectual property we have developed or in-licensed; and our dependence on the success of the LapCap2®Laparoscopic Access Device & Life Care LCMI. Data presented herein may be the result of clinical studies that have yet to be reviewed by the FDA or other international government authority.
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Corporate Overview
• Focused on R&D, production and distribution of non-invasive & minimally-invasive technologies
• Life Care Magnetic Induction Technologies:
- Issued patents
- Numerous pending patents
- Multiple uses and applications
- 510(k) FDA clearance for treatment of numerous tissue conditions
• LapCap2®: Poised to become standard of care for laparoscopic access world-wide
• 1st-Revenue & near-term revenue opportunity, extensive follow-on product pipeline
• Experienced Management Team and Board of Directors
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Management Team and Board of Directors
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Patrick Adams - Chairman• CEO of PVG Asset Management and the Managing Member of Choice
Investment Management
Richard J. Prati – President & Chief Executive Officer
Dr. Camran Nezhat - Chief Medical Officer
Dr. Farr Nezhat• World-renowned authority in advanced laparoscopic and robotic surgery
based in New York City
Dr. Nickolay Kukekov• Co-founder and a principle at Highline Research Advisors, which is an
affiliate of Corinthian Partners LLC
Trevor Moss • Seasoned senior executive and company director with extensive
international experience
Hartman King• Associate at Camp One Ventures
Board of Directors
Richard J. Prati - President and Chief Executive Officer• Over 20 years of proven financial leadership and operational
execution on Wall Street in numerous industries with turnaround expertise
Robin Stephens – Managing Director – MIS• 30 years of medical device experience with leadership from
development through manufacturing and commercialization
Jacques Du Preez – Operations Director – MIS• Over 25 years of operations and finance experience and more than
a decade in medical device experience
Dr. Camran Nezhat - Chief Medical Officer• Internationally renowned laparoscopic surgeon at Stanford
University Medical Center Palo Alto CA, scientist, philanthropist and innovator
Jerry DeCiccio – Financial Controller• Over 25 years as finance officer at public companies, as well as Big
4 CPA, start-up, small and large-cap accounting & operating experience
W. David Mannheim - General Counsel• Senior Partner at Wyrick Robbins with extensive corporate
experience of start-up to large cap companies within health care
Management
Current Products – 2 FDA-Approved Devices
• Physiologic indications
• New category for aesthetics
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• Facilitates laparoscopic access
• Can be utilized in virtually every laparoscopic procedure
• Opens the door for entry into surgical markets
510k clearance: “to assist with veress needle entry…”
Life Care Magnetics LCM-1
510k clearance: “to generate deep heat within body tissues for the treatment of medical conditions…”
• CE-Mark
Life Care Medical Devives (LCMD)
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TECHNOLOGY & INNOVATION
The Markets –Electromagnetic Induction
Well Established and Growing Markets
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• United States skin rejuvenation market: >$3.7 billion
• >12% annual growth in minimally invasive aesthetic procedures
• Projected to >350,000 practitioners as new entrants seek cash pay procedures
1. 1. American Society of Plastic Surgeons;
11%
26%
9%25%
29%
Toxins
Surface
Treatments
Injectable
Fillers
Modern Energy
Devices
Lasers
Skin Rejuvenation Treatment Options
Life Care Magnetic Induction Products
Fueling Entry into Advanced Surgical Markets
• Minimally invasive treatment of
continence
• $3 billion surgical incontinence
market
• Urinary incontinence affects 44% of
people >65-years-old
• Bowel incontinence affects 6% of
adult population, up to 50% of
patients in nursing facilities
• Vaginal Tightening
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• $5 billion market for tissue sealants
• Innovative elastic polymer
adhesives
• Wound closure under pressure
while blood flows
Follow-on products: solutions to medical challenges
Life Care Medical Devices
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TECHNOLOGY & INNOVATION
Modern Magnetics and Medicine
Modern Magnetics and Medicine
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Delivery
Epidermis
Dermis
Subdermal Fat
Muscle
Lasers IPL RF LCMI
1970 1990 1995 2000 2008 2012
US
A novel approach: energy induced in discreet planes beneath the tissue surface*
*All other platforms drive energy directly into tissues – perpendicular to the surface
Life Care Magnetics Innovation
Uniform, planar heat is generated
Magnetics induces currents in moist, conductive tissues; an Electron Vortex forms in the dermal and muscle layers
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Energy is transduced parallel to the surface
The Continuum of Muscle Action
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Toned SpasticFlaccid
Clinical results suggest LCMI relaxes
spastic muscle, and appears to tighten
flaccid muscle suggesting improved
muscle tone as reflected by aesthetic
appearance
Clinical Results
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1 week after 1st treatment2 passes
Clinical Results
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Baseline 1 week after 2nd tx 1 week after 3rd tx
Three passes each tx
Clinical Results
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Before After
30 days after 1st tx2 passes
LCMI Addresses Age-old Problems in Aesthetics
Laser IPL Radiofrequency Ultrasound LCMI
Skin tightening
Muscle toning
No pain/pain reduction
No downtime
No bruising
No tissue damage
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Moderate effect Significant effect
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Life Care Magnetics
Medical Effects
• Pain reduction
• Restoration of mobility
• Correction of contracture
• Reduce muscle spasm
PhysiologicAesthetic*
• Reduction of skin folds
• Improved tone and texture
• Reduction of skin laxity
• Improved muscle tone
*As shown in clinical studies. Device is FDA cleared for delivery of therapeutic heat to tissues.
Physician Economics
Cost per treatment Conservative Projected Revenue per month
$500-$1,000 $25,000 - $50,000
~10,000 dermatologists, plastic surgeons; treat average of 200 patients/mo1
At 3 patients per day (15 per week) = 60 per month x $500 = $30,000/month
Monthly lease options: $15k up front:
• Revenue Share (e.g. $100 per session to LCMD, ~$400 to Physician)• Only Paying if using – so assured positive free cash flow, and incentive to
utilize
1Kythera
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Aesthetic Practice: Patients and Physicians
The Value Proposition for Patients
• Improved skin tone and texture
• Immediate and long term results
• No pain – pain reduction
• No downtime
• No bruising, no tissue damage
• Slight erythema resolves < 1hr
• New device modality with vastly superior cost/efficacy
The Value Proposition For Physicians / Medical Spas
• Substantial incremental cashflow
• No limitations - skin type or pigmentation
• Short procedure options
• Multiple anatomical locations possible
• Simple operation, minimal training necessary
• Outstanding safety profile
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Life Care Medical Devices
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TECHNOLOGY & INNOVATION
Product Pipeline
What is Worse Than Death?
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Incontinence – Large Addressable Market
Potential for minimally invasive restoration of continence
• $3 billion market
• Urinary – 44% of people >65-years-old
• Bowel – high unmet need
- 6% of adult population, more than 50% of patients in nursing facilities
- Straightforward development, relatively short time to market
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Surgical Sealants, Adhesives & Other Markets
• First medical adhesive based on elastic polymers sealed with magnetic induction
• Closes surgical incisions under pressure or while blood is flowing
• Vaginal Tightening
• Cartilage, nasal passage transformation
$5 billion+ market potential
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LCMD adhesive is a futuristic polymer (left) that latches tightly onto
tissues with its anchoring tendrils (right, magnified 1500x by scanning
electron microscopy).
LCMD tissue adhesive and sealant is applied to the bare lung tissue
(center) following excision (left), forming a leak proof, elastic seal (right).
Robust IP Portfolio & Regulatory Approvals
• Life Care LCMI- Issued and pending patents covering methods, devices and compositions
- FDA 510(k) – K121123, therapeutic application of heat to tissues
- IP portfolio favors future product development
• LapCap2- Access to three granted US patents to distribute LapCap2 globally
- Filed design and innovation patents related to LapCap2
- FDA 510(k) – K070651 for Standard size
- CE Marking – for Standard, Small & Large sizes
- ISO 13485 – certified by BSi
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Life Care Medical Devices
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TECHNOLOGY & INNOVATION
Minimally Invasive Surgery
Well Established and Growing Markets
• 1 million+ gynecological laparoscopic procedures annually in the US
• Can be used for both robotic and non-robotic procedures
• ~5 million gynecological lap procedures globally
• Global laparoscopic surgeries utilizing Veress is ~12.5 million equating to a $500+ million market opportunity
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Myomectomies5%
Endometriosis Resection
7%
Ovarian Cysts9%
LGT 3%
Sacrocolpopexy6%
Hysterectomy 51%
Female Sterilization
19%
~1M US Laparoscopic Gynecological Surgeries
LapCap2 - initial target is gynecological laparoscopic procedures
Laparoscopic Entry Associated Complications
• Most common reason for procedural failure?- Inadequate pneumoperitoneum longer OR time increased complications
• 5-10% of cases failed entry attempts increase procedure time = greater risks
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0.0%
25.0%
50.0%
75.0%
100.0%
1 2 3 4+
Pneumoperioneum achieved Complication rate
Veress Needle TechniqueComplication Rate
Complication Rate and Costs
~3,150 annual
complications in the us
~$40 Million in ICU
related injuries
1. Assumes ~1M gynecologic laparoscopic surgeries per year US. (S2N Estimates)
2. Assumes additional mean LOS 3.5 days at $3500k/day ICU cost per day
http://laparoscopy.blogs.com/prevention_management_3//2011/04/laparoscopic-access.html
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304260/
USA Distribution Strategy
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FOCUSED ON REDUCTION IN COMPLICATION RATES
Distribution agreement with Progressive Medical Inc. (PMI) for sales in USA
PMI is a Specialized Private Medical Device Distributor with 75 U.S. Sales Reps
Focused on Laparoscopic/Minimally-Invasive Devices
Heavy Emphasis on Safety and Consistency for Access
Concentrating on University & Teaching Hospitals to teach LapCap as Standard
Method for Laparoscopic Access to Interns, Residents, & New Surgeons
Working with Top Surgeons: Dr Camran Nezhat, Dr. Chuck Miller, and other
Leading Key Opinion Leaders (KOLs)
Rest of World Distribution Opportunity
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NEW COUNTRY EFFORTS
Discussions with Multiple Distributors in the EU including the UK,
Germany and France
Negotiating Currently with an Israeli Distributor who is testing the
product
We have Distributor Requests from Mexico, Colombia, Brazil,
Ecuador, and Chile
We are in active discussions with several distributors in China
We are discussing a contract with one of the largest device
distributors in Japan
Life Care Medical Devices
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Financial Forecast Snapshot
Potential for Meaningful Revenue Generation
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0
20
40
60
80
100
120
140
2016 2017 2018 2019 2020
Sale
s in
$ M
illio
ns
Potential Sales
LCM-1
LapCap2
Total Rev
Based on:• progressive
adoption of LapCap2
• 5 magnetic induction units/month scaling to
• 20 / month by end 2017
• ramping incremental 120 units annually through 2020
Current Offering and Capitalization
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Preferred Shares Offering 2mm shares @ $2.50 per share =$5mm
100% warrant coverage, 8% PIK dividend. Minimum 33% discount
to IPO price.
~10mm Shares Outstanding @ $2.50 (current offer price) = ~$25mm pre$
>$25mm & 10 years spent developing 2 products we have ready for sale today.
Late 2013 initiated management restructuring. Costs & Expenditures reduced by
>60%, thus repositioning the company for success.
January 2014 – raised ~$1.5mm at 50¢. May 2015 – raised $750k at $1.50
Between June 2015 – March 2016 – raised roughly $750k between $2.00-$3.00
We expect to bring LCMD back on the public markets by Q3 or Q4 2017
Medical Device Value Indicators – Recent Exits
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Year Company Acquirer Amount
2014 $250 M
2014 $600 M
2013 $294 M
2013 $240 M
2012 $91 M
Life Care Medical Devices
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2017e 2018e
Revenue Range $4mm - $10mm* $12mm - $30mm
COGS/OPEX $7mm - $9mm $9mm-$24mm
Pre-Tax Income ($3mm) –$1mm $3mm - $6mm
Forecast Financial Metrics with $5mm Capital Raise by end of Q1 2017
* At 75 to 90 units shipped on the magnetics side, we anticipate we will hit cash flow break-even
Comp Table: Public & Private Medical Device & Aesthetics Companies
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Comparable/
Acquirer
TICKER 1/6/2017
Market Cap
Private
Valuation
Company Highlights and Commercial Prospects
Life Care Medical**(based on current cap
table with ~10mm shares)
LCMD*(*Reserved)
$25MM** (Based on
current
Offering)
2 FDA-Approved Medical Devices available for sale today. RF through electro-magnetic
induction. New technology, cost-effective, not painful, can reach & tone muscle, & pipeline of
new Indications also revenue-generating LapCap2 - Laparoscopic device w/ CE-Mark
Miramar Labs MRLB $40MM Aesthetic treatment for underarm hair, underarm sweat, excess sweat
Viveve Medical VIVE $55MM Recently Received FDA-approved, Uses RF energy for vaginal tightening
PAVmed Inc. PAVM $80MM Pre-revenue. Five disparate medical devices expected to be approved by end of 2017, and
first revenue expected in 2018. IPO May 2016
Cynosure, Inc. CYNO $1.1B $294MM Broad-range of lasers products for a variety of aesthetic applications
Zeltiq Aesthetics ZLTQ $1.7B $91MM Focused on CoolSculpting Technology to freeze and eliminate fat cells
Ulthera/Merz Private PRIVATE $600MM Ultrasound Technology - effective and can reach muscle layer, but expensive/painful
Alma Lasers/Fosun FOSUY $12B $240MM Laser Technology - various types - expensive and surface treatment
Solta Medical/Valeant VRX $5.2B $250MM Laser Technology - various types - expensive and surface treatment
www.lcmd.com
Reshaping
Treatment Paradigms
Corporate Presentation© Life Care Medical Devices 2017