recommandations ssgo dépistage cancer du col utérin©sentations/grssgo mars... · dépistage...

Recommandations SSGOdeacutepistage cancer du col uteacuterin

Pr Patrick Petignat

University Hospitals of Geneva

GRSSGO 2018

Pap test for cervical cancer screening A success story

bull Introduce essentially by gynecologists in last 60

(annual control)

bull Opportunist

bull Cytology-based (conventional ndash LBC)

bull HPV for ASCUS triage

Cervical cancer screening Switzerland

Incidence CH 53 100 000NICER Cancer IncidenceSwitzerland wwwnicerorgenstatistics-atlascancerincidenceaccessed 01 08 2014

bull Participation rate Switzerland 70-80ndash Belgium 61ndash Norway 866ndash England 785-835

Richard et al Cancer Epidem 2015Arbyn et al PlosOne 2015Bang et al J Public Health 2012Jeangros et al Eur J Public Health 2016

Swiss CC coverage rate

Incidence rates of invasive cervical cancer by region Switzerland 1983-2007

0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
Std rates per 100 000
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col

age specific inc rates


age group
Rates per 100 000
Age specific incidence rates of cervical cancer Switzerland 2003-2007
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31

trends inc par classe dage


SA
SL
CH
year
Incidence rates of invasive cervical cancer Switzerland 1983-2007
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
Crude rates per 100 000
Incidence rates of invasive cervical cancer by age group Switzerland 1983-2006
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
STD rates per 100 000
Incidence of invasive cervical cancer by regional registry Switzerland 2003-2007
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
Mortality rates of invasive cervical cancer Switzerland 1983-2007
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
Age specific mortality rates of cervical cancer Switzerland 2003-2007
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579

Cervical cancer is a public health

problem

60 cervical cancer incidence

reduction

False-positive cytology is public

health proble

European countries adopt HPV primary

screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT

HPV deacutepistage NL

20201960

Cervical cancer screening in Switzerland

Area to be consideredbull Screening women 20+ (optimal screening intervals)bull Screening women 30+ (potential for primary HPV testing (no Pap))

bull Possible harm from screeningbull Anxiety over a positive testbull Painbleeding from proceduresbull Treatment-related pregnancy complicationsbull Number of colposcopies is a marker for harms

We can imagine thathellip

0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10Nb of intervention Courtesy M Boulvain

SCREENING INTERVAL

About 75-80 of population have HPV exposure hellip and gt95 will clear the infection

About 70-80 () will have CIN1 and most will regress without treatment hellip they have little neoplastic potential and maybe only 1 may develop into a cancer

Transient infection (HPV and LSIL)SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20

Transient infection (HPV and LSIL)

gt2 yrs sim 5 yrs sim10 yrs

SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30

Allow regression of ldquotransientrdquo lesions


SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000

ASC-US40000 Based on 12 million testsy

Courtesy P Vassilakos

Cervical cancer is not a main public health concern in Switzerland

Abnormal Pap

are major public health concerns

Cytology-based screening false positive rateSCREENING INTERVAL

Benefits HarmsOver-diagnosisOver-treatment

Anxiety Prevent CancerReduce MorbidityMortality

Determine the level of risk that is acceptable and the harms of screening

Optimize the screening SCREENING INTERVAL

HPV and Cervical Cancer

Over 99 of cervical cancers have HPV DNA detected within the tumor

70 of cervical cancer is caused by one of two types of HPV 16 or 18

HPV TESTING lt30

Murphy et al 2012 JOGC

HPV TESTING lt30

Cumulative Incidence of CIN3+

Dillner et al BMJ 2008

HPV TESTING lt30

Benefice of HPV testing

bull Increased detection of prevalent CIN3

bull Decreased CIN3 in subsequent screening rounds

bull Enhances detection of adenocarcinomaAIS

bull Minimizes the increased number of colposcopies thus it reduces harms

HPV TESTING lt30

Reminder ndash Swiss policy 2012

Age Screening interval21 ndash 30 years 2 years31 ndash 70 years 3 years

2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018

Age Screening interval21 ndash 30 yrs 3 years cytology31 ndash 70 yrs 3 years cytology or HPV with triage

cytology

2018

Doesnrsquot include CIN2 CIN3 women infected with HIV or immunocompromised (solid organ transplants)

21 ndash 70 yrs Every 3 years

Swiss policy 2018 (21-29 yrs old)

1 Women lt21 yrs should not be screened regardless of age of sexual onset and other behavior-related risk factors

2 Women gt21 yrs who no sexual intercourse may not need a Pap test (to be decided women and physician)

3 Women 21-29 yrs cytology alone every 3 years

4 Recommend against ldquohellip three consecutive annual cytology beforehelliprdquo

5 Recommend against HPV testing (alone or in combination with cytology) in women aged lt30 years

6 Vaccinated = unvaccinated

2018


1 Women 30-70 yrs every 3 years HPV testing (alone) or cytology

2 If HPV ndash women should be informed about the HPV price (no reimbursement)

3 If HPV - screening should begin 3 years after the last negative cytology

4 Recommend against co-testing (concomitant HPV and cytology)

5 Recommend against testing HPV low-risk

2018

Women and physician choice

Swiss policy 2018 (stop)

1 Stop at age 71 for women with adequate negative prior screening (no CIN2+)

2 Stop after hysterectomy with removal of cervix (no history of CIN2+)

2018

Age Screening interval

coverage rate

IncidenceCancer cervical

100 000Belgium 25-64 3 58 93Denmark 23-65 3-5 75 126England 25-64 3 agrave 5 83 83Finland 30-65 5 80 43France 25-65 3 69 98Italy 25-64 3 53-74 81Netherland 30-60 5 77 73Spain 20-64 3 agrave 5 496 76Switzerland 21-70 3 72 52Sweden 23-60 3 83 82

Cervical Cancer Screening Programs in 19 ICSN Countries 2012 Organization Policies

and Program Reach JNCI 2017

Swiss policy 2018

Norway - 4 countiesHPV primary screening

Sweden ndash HPV primary screening

England - HPV as primary screening

Netherlands - HPV primary screening (implemented)

Italy - 3 counties HPV primary screening

Finland - HPV primary screening in guidelines

Adapted from Melchers

Disparity between guidelines and practice -Anecdotes

ldquoWomen were savedrdquo by a pap test in young agehellip

ldquoI discover a HSIL at 16 years oldrdquo

ldquoWomen were saved she was 72 years oldrdquo

bull From women perspectivendash New recommendation may appear to decrease service for the

purpose of saving money for insurer

ndash Many women are not interested in assuming more cancer risk even if the harm is significant

bull Improve quality and lower costs of care for patients

Perception of change


bull From Healthcare provider perspective- Consider Pap smears to be part of every womanrsquos annual visit

- Women will not come for an annual check-up and may be less inclined to undergo screening

bull Do not minimize harm from overusehellip practicing medicine according to guideline is a strong appeal to our professionalism

Conclusion

bull Provider must understand guidelines and reasons behind (harm and benefit)

bull Must explain to patients controversies (when to start interval and stopping)

bull Must help women to make their own decisions

bull Biggest gain would screening among women neverrarely screened

Thank you for your attention

Case ndash Swiss policy

A 45 yo new patient who says she has ldquoalwaysrdquo had a Pap test and would like to have a cervical cancer screening


You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


Lifetime risk of colposcopy

bull Pap test 3 yrs 760 colpos1000 women


bull Pap test 1 yr 2000 colpos1000 women

Stout NK et al Arch Intern Med 2008168181

Diapositive numeacutero 1











Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018


Disparity between guidelines and practice - Anecdotes



Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL

Periods Number of cases Yearly average Periods

1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140

Age std rates (European population)

1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence

Periods Number of cases Yearly average European standardized rate

1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52

Age specific rates - 2003-2007

0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence

Crude rates by age-group amp mean annual trends

Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073

Area Rates 2003-2007 95 CI

GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Pap test for cervical cancer screening A success story


(annual control)

bull Opportunist









0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07


(annual control)

bull Opportunist









0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07






0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+


0

2

4

6

8

10

12

1983-87 1988-92 1993-97 1998-02 2003-07

year

Std

rate

s pe

r 100

000

SASL CH

2008-2012

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Graph5

SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

INC ca col



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

Incidence


1983-87 2023 405 Periods SA SL CH

1988-92 1735 347 1983-87 1119 1108 1115

1993-97 1778 356 1988-92 912 877 902

1998-02 1485 297 1993-97 901 786 868

2003-06 932 233 1998-02 731 589 689

2003-07 534 479 518


1998-02 69

2003-06 52


0- 0

5- 0

10- 0

15- 01

20- 08

25- 31

30- 61

35- 97

40- 93

45- 93

50- 93

55- 71

60- 76

65- 85

70- 8

75- 13

80- 79

85+ 113

Incidence


Periods 0-19 20-49 50-69 70+

1983-87 0 111 2212 2308

1988-92 0 96 1608 1988

1993-97 0 1079 1401 1718

1998-02 003 914 1006 1461

2003-06 004 673 801 1073


GRGL 78 21 26

TI 63 15 18

VS 57 15 19

ZH 54 07 08

SA 53 08 09

SGA 53 11 13

CH 52 11 12

SRT 48 06 06

VD 46 09 11

NE 43 17 23

BSBL 4 11 14

GE 38 1 12

FR 36 2 32



age group
Rates per 100 000
0
0
0
01
08
31
61
97
93
93
93
71
76
85
8
13
79
113

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-

0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

trends inc suisse

0
0
0
01
08
31



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

0-

5-

10-

15-

20-

25-



SA
SL
CH
year
1119
1108
1115
912
877
902
901
786
868
731
589
689
534
479
518

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Comp cantons

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

Comp cantons

0-19
20-49
50-69
70+
year
0
111
2212
2308
0
96
1608
1988
0
1079
1401
1718
003
914
1006
1461
004
673
801
1073

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

1983-87 1983-87 1983-87 1983-87

1988-92 1988-92 1988-92 1988-92

1993-97 1993-97 1993-97 1993-97

1998-02 1998-02 1998-02 1998-02

2003-06 2003-06 2003-06 2003-06

Mort ca col

Registry
78
63
57
54
53
53
52
48
46
43
4
38
36

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

GRGL 26 21

TI 18 15

VS 19 15

ZH 08 07

SA 09 08

SGA 13 11

CH 12 11

SRT 06 06

VD 11 09

NE 23 17

BSBL 14 11

GE 12 1

FR 32 2

curve morta rates

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

Mortality SA CH SL


1983-87 885 177 1983-87 453 441 412

1988-92 745 149 1988-92 364 342 288

1993-97 631 126 1993-97 295 274 223

1998-02 456 91 1998-02 196 180 140

2003-06 352 88 2003-07 176 165 140


1998-02 18

2003-06 17

Mortality

0- 00

5- 00

10- 00

15- 00

20- 00

25- 01

30- 04

35- 08

40- 11

45- 20

50- 23

55- 38

60- 42

65- 54

70- 55

75- 79

80- 101

85+ 104

23

age spec mort

SA
CH
SL
years
45292403095
44087751852
4115611488
36365651298
34191976482
28829893735
29511768691
27434174734
22335853374
19607189035
17967472282
13973465228
17585577482
16519593353
13968953982

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+

1983-87 1983-87 1983-87

1988-92 1988-92 1988-92

1993-97 1993-97 1993-97

1998-02 1998-02 1998-02

2003-07 2003-07 2003-07

age groups
Rates per 100 000
0
0
0
0
0
00849015354
03756492158
07851892371
10992421695
20321515404
23382703089
37774780046
41914502037
54133121408
55453610534
7946643962
101023527848
104000876579


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






0-

5-

10-

15-

20-

25-

30-

35-

40-

45-

50-

55-

60-

65-

70-

75-

80-

85+


problem


reduction


health proble


screening

1970 2015

CytologyScreening

2010

Vaccination

HPV RCT


20201960





0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion










0102030405060708090

100

0 1 2 3 4 5 6 7 8 9 10

Improvement

Nab of intervention

SCREENING INTERVAL

Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






Buthellip

0102030405060708090

100


SCREENING INTERVAL




HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion









HPV+ CIN1 CIN2 CIN3


HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






HPV+ CIN1 CIN2 CIN3

CA

1 5 20



SCREENING INTERVAL

HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






HPV+ CIN1 CIN2 CIN3

CA

1 5 20

HEALTHY

9860 50 30



SCREENING INTERVAL

Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






Ca300

HSIL7000

LSIL30000




Abnormal Pap










HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion













HPV TESTING lt30


HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion







HPV TESTING lt30



HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion








HPV TESTING lt30






HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion











HPV TESTING lt30



2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion








2012

Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






Swiss policy2018

WWWSGGGCH

Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






Swiss policy 2018


cytology

2018










2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion













2018







2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion












2018





2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion









2018


coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion







coverage rate





Swiss policy 2018





















Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion


























Conclusion









You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion










You recommend

1 HPV test

2 Pap test

3 Co-testing


You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion







You recommend

1 Annually

2 Every two years

3 Every three years


















Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion























Buthellip












Swiss policy

Swiss policy 2018




Swiss policy 2018





Conclusion






1983-87	1983-87	1983-87

1988-92	1988-92	1988-92

1993-97	1993-97	1993-97

1998-02	1998-02	1998-02

2003-07	2003-07	2003-07

	Mortality				SA		CH		SL

Periods		Number of cases	Yearly average			Periods

1983-87		885	177			1983-87		453		441	412

1988-92		745	149			1988-92		364		342	288

1993-97		631	126			1993-97		295		274	223

1998-02		456	91			1998-02		196		180	140

2003-06		352	88			2003-07		176		165	140

	Age std rates (European population)

1998-02		18

2003-06		17

				Mortality

			0-		00

			5-		00

			10-		00

			15-		00

			20-		00

			25-		01

			30-		04

			35-		08

			40-		11

			45-		20

			50-		23

			55-		38

			60-		42

			65-		54

			70-		55

			75-		79

			80-		101

			85+		104

				23

GRGL	26	21

TI	18	15

VS	19	15

ZH	08	07

SA	09	08

SGA	13	11

CH	12	11

SRT	06	06

VD	11	09

NE	23	17

BSBL	14	11

GE	12	1

FR	32	2

	Incidence

Periods		Number of cases	Yearly average			European standardized rate

1983-87		2023	405		Periods		SA		SL	CH

1988-92		1735	347		1983-87		1119		1108	1115

1993-97		1778	356		1988-92		912		877	902

1998-02		1485	297		1993-97		901		786	868

2003-06		932	233		1998-02		731		589	689

			2003-07	534		479		518

	Age std rates (European population)

1998-02		69

2003-06		52

				Age specific rates - 2003-2007

				0-		0

				5-		0

				10-		0

				15-		01

				20-		08

				25-		31

				30-		61

				35-		97

				40-		93

				45-		93

				50-		93

				55-		71

				60-		76

				65-		85

				70-		8

				75-		13

				80-		79

				85+		113

	Incidence

Crude rates by age-group amp mean annual trends

Periods		0-19	20-49	50-69		70+

1983-87		0	111	2212		2308

1988-92		0	96	1608		1988

1993-97		0	1079	1401		1718

1998-02		003	914	1006		1461

2003-06		004	673	801		1073

Area		Rates 2003-2007	95 CI

GRGL		78	21	26

TI		63	15	18

VS		57	15	19

ZH		54	07	08

SA		53	08	09

SGA		53	11	13

CH		52	11	12

SRT		48	06	06

VD		46	09	11

NE		43	17	23

BSBL		4	11	14

GE		38	1	12

FR		36	2	32

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Documents

Graph5

INC ca col

age specific inc rates

age specific inc rates

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curve morta rates

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Graph5

INC ca col

age specific inc rates

age specific inc rates

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trends inc par classe dage

Comp cantons

Comp cantons

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curve morta rates

age spec mort

Graph5

INC ca col

age specific inc rates

age specific inc rates

trends inc suisse

trends inc par classe dage

trends inc par classe dage

Comp cantons

Comp cantons

Mort ca col

curve morta rates

age spec mort

Graph5

INC ca col

age specific inc rates

age specific inc rates

trends inc suisse

trends inc par classe dage

trends inc par classe dage

Comp cantons

Comp cantons

Mort ca col

curve morta rates

age spec mort

Graph5

INC ca col

age specific inc rates

age specific inc rates

trends inc suisse

trends inc par classe dage

trends inc par classe dage

Comp cantons

Comp cantons

Mort ca col

curve morta rates

age spec mort

Graph5

INC ca col

age specific inc rates

age specific inc rates

trends inc suisse

trends inc par classe dage

trends inc par classe dage

Comp cantons

Comp cantons

Mort ca col

curve morta rates

age spec mort

Graph5

INC ca col

age specific inc rates

age specific inc rates

trends inc suisse

trends inc par classe dage