S8 Oral Presentation Sessions / International Journal of Cardiology 163S2 (2013) S1–S30

A015Comparison of more than 3 years clinical outcomes betweendrug-eluting stents and coronary artery bypass graft forunprotected left main disease

D.X. Wang, C.H. Zhou, H. Liu, L.R. Yan, X.X. Zhang. Key Laboratory ofClinical Trial Research in Cardiovascular Drugs, Ministry of Health, StateKey Laboratory of Cardiovascular Diseases, Fuwai Hospital, NationalCenter for Cardiovascular Diseases, Chinese Academy of MedicalSciences and Peking Union Medical College, China

Purpose:We sought to perform ameta analysis to combine the avail-able randomised and nonrandomised studies examine the clinical ef-fect of drug-eluting stents (DES) and coronary artery bypass graft(CABG) in unprotected left main disease (UPLM) with more than 3year follow-up.Methods: A systemic research was carried out in Pubmed, Embase,Cochrane library and scientific sessions of AHA, ACC and ESC (up toOct 2012). All randomised and nonrandomised studies after≥3 yearsof follow-up comparing DES and CABG in UPLMwere included. In ob-servational studies, risk adjusted hazard ratio (HR) or odds ratio (OR)were extracted. Sensitivity analyses and publication analyses werealso performed to confirm the reliability of results.Results: 11 eligible studies (2 randomised, 9 nonrandomised)with 6858 subjects were identified and selected. Mortality,death/MI/stroke and target vessel revascularizaton (TVR) were fo-cused. Pooled analysis revealed that there was no statistical signif-icant difference between DES and CABG in mortality (OR=0.95, 95%confidential interval [CI]: 0.81 to 1.13, P=0.586, heterogeniety test:0.0%; Fig. 1) and death/MI/stroke (OR=0.94, 95% CI: 0.80 to 1.11,P=0.473, heterogeniety test: 0.0%).However, compared with CABG,DES had a significant increased incidence of TVR (Random-effectmodel, OR=3.56, 95% CI: 2.66 to 4.71, P<0.001, heterogeniety test:45.9%). No evidence of significant publication bias was observedin mortality (Begg’s test, P=0.325; Egger’s test, P=0.407). Sensitivityanalysis of mortality excluding each included study at one time re-vealed that most individual study was consisted with the directionand size of the overall effect (all P>0.1).

Figure 1

Conclusion: Based on the available evidence, after long-term followup, the mortality and composite outcome are similar between DESand CABG in patients with UPLM, however, incidence of TVR is stillhigh in DES comparing with CABG.

Others

A016 – SmokingPsychological predictors of stage of readiness to quit amongHong Kong Chinese smokers: the role of social acceptance ofsmoking by family

D.Y.P. Leung1, E.M.L. Wong1, S.S.C. Chan2. 1The Nethersole School ofNursing, The Chinese University of Hong Kong, Hong Kong, China;2School of Nursing, The University of Hong Kong, Hong Kong, China

Purpose: The Attitude-Social Influence-Efficacy (ASE) model hasbeen used to gain insight into the determinants and guide the devel-opment of interventions for smoking cessation. In addition, a partic-ular personality trait, conscientiousness, was also reported affectingmotivation to quit among smokers. This study aims to explore theASE and personality predictors of readiness to quit smoking amongHong Kong Chinese smokers.Methods: A longitudinal study was conducted with 309 Hong Kongresidentswho aged>15 years old and smoked≥1 cigarette in aweekin the past 6 months in Feb-Dec 2010. A path model linking stage ofreadiness to quit at 3-month to eight baseline variables: priority ofquitting, social support, social acceptance of smoking by family, so-cial acceptance of smoking by friends, self-efficacy to resist smokingdue to internal and external stimuli, and stage of readiness to quit,and conscientiousness was fitted to the data.Results: We successfully followed-up 219 (70.9%) participants and203 (92.7%) had provided completed responses in all the variablesin the analysis. Their mean age was 27.6±12.4 years, 49.8% weremale, 76.4% were married and 69.9% had education level of ≥Form 4–5. A good fit to the data was obtained (R-χ2=21.15, df=21,R-CFI=0.999, SRMR=0.064, R-RMSEA=0.006). Stage of readiness toquit at 3-months was predicted significantly by stage of readiness(β=0.73) and social acceptance of smoking by family (β= –0.16) butnot self-efficacy to resist smoking due to internal (β=0.08) and exter-nal stimuli (β= –0.07) at baseline. Conscientiousness, social support,and priority of quitting have indirect effects on stage of readiness toquit at 3 months.Conclusion: The results suggest that social acceptance of smoking byfamily seems to play a more important role in motivating smokersto quit. While current smoking cessation programmes focus mainlyon enhancing self-efficacy to resist smoking, future development incessation interventions can also include smokers’ family members bystopping the smokers to smoke around them.

A017 – Cardiovascular MultimorbidityFactors associated with cardiovascular multimorbidity amongprimary care patients in southern China

H.H.X. Wang1, M.C.S. Wong1, S.Y.S. Wong1, J.L. Tang1, B.P. Yan2,C.M. Yu2, J.J. Wang3, D.K.T. Li4, S.M. Griffiths1. 1School of PublicHealth and Primary Care, Faculty of Medicine, The Chinese University ofHong Kong, Hong Kong; 2Division of Cardiology, Faculty of Medicine,The Chinese University of Hong Kong, Hong Kong; 3School of PublicHealth, Guangzhou Medical University, P.R. China; 4BauhiniaFoundation Research Centre, Hong Kong

Purpose: Management of the rising prevalence of long-term con-ditions is one of the major challenges facing China’s current pri-mary care reform. Better understanding of factors associated withcardiovascular multimorbidity is necessary to develop a comprehen-sive strategy to support primary care physicians in China to providepatient-centred and continuous care. This study aimed to examinefactors on individual socio-economic status in relation to the preva-