Cataract

Yesi Putri ari Hartiningrum

I11107031

Definition

an abnormal progressive condition of the lens of the eye, characterized by loss of transparency.

A yellow, brown, or white opacity can be observed within the lens, behind the pupil.

Etiology

Physical

Chemical

Predisposition of other disease

Genetic and development disorder

Viral infection in fetal growth

Aging

Signs and symptoms

Reduced visual acuity (near and distant objects)

• Glare and halo in sunshine or with street or car lights

• Distortion of lines

• Monocular diplopia

• Altered colours (white objects appear yellowish).

• Not associated with pain, discharge or redness of the eye

• Inability to fix visual on a target

Classification

Classified by etiology Classified by opacities Classified by location of opacity within lens

structure Classified by maturity

Classification by etiology

Age-related cataract Congenital cataract Secondary cataract Traumatic cataract

A. Age-related cataract It is acquired lens opacity occurring old age in the absence of a

local or systemic disease.

The general features : Always bilateral (one eye precedes the other). Progressive to maturity and hypermaturity. Hard nucleus. No local or systemic disease can be found.

Clasification : Cortical Senile Cataract Senile Nuclear Cataract Subcapsular Senile Cataract

B. Congenital cataract Hereditary Congenital Cataracts Cataract from Transplacental Infection in the First Trimester of

Pregnancy Without systemic association : isolated hereditary cataracts Systemic association : metabolic(galactosemia, galaktokinase

deficiency), prenatal infection,chromosomal abnormalities, skeletal syndrom

Classification : Lamellar or zonular cataract Opacities are located in one layer

of lens fibers, of ten as “riders” only in the equatorial region Nuclear cataract The lamellar cataract in which initially only the

outer layer of the embryonic nucleus is affected. Coronary cataract Fine radial opacities in the equatorial region. Cerulean cataract Fine round or club-shaped blue peripheral

lens opacities.

C. Secondary cataract Drug-induced cataract (e.g. corticosteroids) Diabetic cataract atypical radial snowflake pattern of

cortical opacities (snowflake cataract) Galactosemic cataract Deep posterior cortical opacity

begins after birth Dialysis cataract swelling of the cortex of the lens Tetany cataract The opacity lies within a broad zone

inferior to the anterior lens capsule and consists of a series of gray punctate lesions

Dermatogenous cataract (e.g. chronic neurodermatitis, scleroderma, etc) anterior crest-shape d thickening of the protruding center of the capsule

D. Traumatic cataract

Blunt trauma (capsule usually intact) Penetrating trauma (capsular rupture & leakage of

lens material)

Classification by opacities(Lens Opacities Classification System III)

Classification by location of opacity within lens structure

Anterior & Posterior cortical cataract Anterior & Posterior polar cataract Anterior & Posterior subcapsular cataract Nuclear cataract posterior capsular opacification

(PCO)

Cortical cataract : Develops in the outer shell of the lens as spokes and wedges and

commonly causes increasing glare sensitivity.

Commonly process due to increased water/ fluid content inside the lens.

A history of diabetes or previous heart attack, and a blood factor

(fibrinogen) associated with vascular conditions appeared to increase

the risk

Tend to be hyperopia

Subcapsular Cataract :

Starts as a small, opaque area just under the capsule shell, usually at

the back of the lens

This type of cataract may occur in both eyes but tends to be more

advanced in one eye than the other

Often interferes with reading vision, reduces your vision in bright light

and causes glare or halos around lights at night

Posterior subcapsular cataract : Develops at the back of the lens, often in the visual axis, and so affects

vision rapidly and severely

The majority of people needing cataract surgery have some posterior

subcapsular cataract present at that time

Nuclear cataract : Develops in the nucleus or centre of the lens, due to hardening

process.

As it increases, there is an associated yellow or brown discolouration of

the lens.

smoking, heavy alcohol consumption, sunlight exposure and diabetes

increased the risk of nuclear cataract.

Produce myopia

(A, bipolar; B, pyramidal; C, axial; D, subcapsular (cupuliform); E, nuclear; F, coronary; G, snowflake; H, cuneiform)

Classification by maturity Intumescent The lens becomes swollen by absorbing

water. Immature Scattered opacities are separated by clear

zones. Mature Cortex and nucleus become totally opaque. Hyper-mature Cataract Mature cataract, which has

become smaller and has a wrinkled capsule as a result of leakage of water out of lens.

Morgagnian Cataract A Hyper-mature cataract, in which total liquefaction of cortex allows the nucleus to sink inferiorly.

Insipien Cataract :

Intumescent Cataract :

Immature Cataract :

Mature Cataract :

Hyper-mature Cataract :

Morgagnian Cataract :

Examinations Visual acuity : Checking vision of both eyes unaided and aided with

glasses and pin-hole vision to know the improvement as well as to get the general idea about the macular function of the eyes. This will help in prognostic evaluation of visual recovery after cataract surgery.

Slit-lamp examination : To know the type of cataract along with its opacity, morphology and etiology or any associated ocular pathology.

Direct and indirect ophthalmoscopy (Brückner’s test): : Dense opacity (cataract will prevent retinal evaluation), Under a light source or ophthalmoscope (set to 10 diopters), opacities will appear black in the re d pupil

Prevention

wearing ultraviolet-protecting sunglasses Regular intake of antioxidants (such as

vitamin A, C and E) antioxidant N-acetylcarnosine

Treatment

Improving the vision for a while : using new glasses, strong bifocals, magnification,

appropriate lighting

Cataract surgery extracapsular cataract extraction (ECCE) intracapsular cataract extraction (ICCE) Small Incission Cataract Surgery (SICS) Phacoemulsification

extracapsular cataract extraction (ECCE)

only the cortex and nucleus of the lens are removed ( extracapsular extraction); the posterior capsule and zonule suspension remain intact. This provides a stable base for implantation of the posterior chamber intraocular lens.

ECCE is a conventional technique that :

ECCE requires an incision of 10-12mm

The doctor removes the clouded lens in one piece.

Multiple stitches are required.

He implants a non-foldable lens.

This not only provides support of placement of IOL but also

prevents vitreous from bulging forwards and acts as a barrier

between anterior and posterior segment

All this results in decreasing the incidence of complications :

Vitreous loss, corneal edema, endophthalmitis, cystoid macular

edema, aphakic glaucoma, etc.

intracapsular cataract extraction (ICCE)

The lens is removed as one single piece i.e., the nucleus and the

cortex are removed within the capsule of the lens after breaking

the zonules. The entire lens is frozen in its capsule with a cryophake and

removed from the eye through a large superior corneal incision

There is no support left for posterior chamber IOL, therefore,

only anterior chamber IOL (ACL) can be implanted which has

risk of adverse corneal complications.

There is no barrier left between anterior and posterior

segment, which increases the incidence of other

complications e.g., vitreous loss, aphakic glaucoma, cystoid

macular edema, endophthalmitis, etc

Small Incission Cataract Surgery (SICS)

The difference with ECCE is by the size of the incission (Incission ± 5-7 mm)

Do not need suture

Phacoemulsification

It is an advancement in the method of doing ECCE.

The nucleus is converted into pulp or emulsified using high

frequency (40,000 MHz) sound waves, and then is sucked out

of the eye through a small (3.2 mm) incision or micro incision

(less than 1.5 mm).

A special foldable IOL is then inserted into the posterior

chamber through the same incision.

Diabetic Retinopathy

Diabetic Retinopathy

Is a progressive ophthalmic condition that is associated with diabetes and can have devastating consequences

It is a leading cause of blindness in adults of working age and is characterised by capillary leakage, capillary vessel occlusion and subsequent new vessel formation.

Retinopathy will develop within 5 years of diagnosis of diabetes in approximately: 25% of people with Type 1 diabetes 40% of people with Type 2 diabetes who are taking insulin 24% of people with Type 2 diabetes who are not taking

insulin

Classification

Non-proliferative diabetic retinopathy (NPDR) Proliferative diabetic retinopathy (PDR) Diabetic maculopathy

Non-proliferative diabetic retinopathy (NPDR) Capillaries develop leaks and later become occluded.

Do not have much effect on vision when they occur in the peripheral retina

The retinal changes : Mycroaneurysms Intra-retinal hemorrhages Venous bleeding Excessive hemorrhages Cotton-wool spot (nerve fiber infaction with soft exudates) hard yellow exudates with well defined edges macular edema

Proliferative diabetic retinopathy (PDR)

Typified by the growth of new vessels on the retina or into the vitreous cavity and thought to result from the ischaemic diabetic retina producing vasoproliferative factors that cause the growth of abnormal new vessels.

The retinal changes : Pra-retinal neovascularization Vitreous hemorrhages Tractional retinal detachment Rubeosis iridis (neovascularization of the iris that can occlude

the angle of anterior chamber)

Diabetic maculopathy When diabetic retinopathy causes vessel leakage and ischaemia

in the macula area

occurs more commonly in type II diabetics

Classification : Focal focal leakage from a microaneurysm or dilated

capillaries and surrounding exudates are seen (Figure 21.5). Diffuse oedema diffuse leakage from dilated capillaries at the

posterior pole of the eye. Retinal oedema is diffuse and can be associated with microaneurysms and few haemorrhages but exudates are absent (Figure 21.6).

Ischaemic maculopathy by closure of the perifoveal and surrounding vascular network. In addition to diffuse oedema, several dark haemorrhages might be present (Figure 21.7a).

Focal maculopathyDiffuse oedema maculopathy

Ischaemic maculopathy

Symptoms

Asymptomatic for a long time The late stages with macular involvement or

vitreous hemorrhage will the patient notice visual impairment or suddenly go blind

Treatments

Control of diabetes Proliferative diabetic retinopathy scatter

photocoagulation macular edema focal laser treatment

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