programme a4 espt 0609 - altilabnewsletters.altilab.com/espt/2015/espt2015program.pdf ·...
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Under the auspices of the Medical Section of the Hungarian Academy of Sciences
Scientific Programwww.esptcongress.eu
ESPT 2015Third ConferenceIntegration of Pharmacogenomics in clinical decision supportOctober 7-8-9, 2015Hungarian Academy of SciencesBudapest, Hungary
Wednesday 7 October 201508:00-09:00 Registration
09:00-10:00 OPENING CEREMONY > Prof Gyorgy Németh, Budapest, representing HSPM (Hungarian Society of Personalised Medicine) - Welcome
The representative of:The University and Academy of Science > Prof Judit Molnar, Budapest, HungaryThe Minister of Health: >TBCThe President of:EFLM (European Federation of Clinical Chemistry and Laboratory Medicine) > Prof Mauro Panteghini, Milano, Italy or his representativeEPHAR (The Federation of European Pharmacological Societies) > Prof Thomas Griesbacher, Vienna, Austria IFCC (International Federation of Clinical Chemistry and Laboratory Medicine) > Prof Maurizio Ferrari, Milano, ItalyIUPHAR (International Union of Basic and Clinical Pharmacology) > Prof Guilherme Suarez-Kurtz, Rio de Janeiro, BrazilESPT (European Society of Pharmacogenomics and Personalised Therapy.vA Scientific Society for Individualised Medicine) > Prof Gérard Siest, Nancy, France
10:00-11:00 OPENING LECTURES Co-chairs: Urs A. Meyer, Basel, Switzerland / Magnus Ingelman-Sundberg, Stockholm, Sweden
10:00-10:30 > Dan Roden, Nashville, USA - Vanderbilt and North American experience of opportunities and challenges of pharmacogenomics and personalized medicine and of their clinical implementation
10:30-11:00 > Michael Hayden, Tel Aviv, Israel - Personalized Medicine in Neurological Disorders
11:00-11:15 Break
11:15-13:15 USE OF OMICS DATA FOR PERSONALIZED MEDICINE Co-chairs György Németh, Budapest, Hungary / Guilherme Suarez-Kurtz, Rio de Janeiro, Brazil
11:15-11:40 > György Németh, Budapest, Hungary - New challenges of the decade: the value of personalized and translational medicine11:40-12:05 > Maurizio Ferrari, Milano, Italy - Omics: from bench to benside 12:05-12:30 > Markus Paulmichl, Salzburg, Austria - Pharmacogenomics implementation: what are the Pitfalls?12:30-12:55 > Michael Neumaier, Heidelberg, Germany - The OMICS dimension in the age of molecular cancer diagnostics12:55-13:15 > Candan Hizel, Izmir, Turkey - Merging pharmacogenomic and phenomic data for Patient Drug Metabolism
Efficacy by Help Decision Making System
13:15-14:15 Lunch Break – Posters’ Visit
14:15-15:15 WORKSHOP 1 - THERMOFISHER New developments for your Pharmacogenomics research Coodinator: Peter Jacobs, Gent, Belgium
> Le Ferrier, San Francisco, USA - Overcoming PCR Inhibitors to Achieve Rapid, Accurate Results in a High Throughput Pharmacogenomics Sample-to-Answer Solution
> Dominique Dewolf, Saint Aubin, France - CYP2D6 allele specific copy number analysis using TaqMan® SNP Genotyping Assays and digital PCR
15:15-15:30 Break
15:30-17:30 INTERINDIVIDUAL DIFFERENCES
OF DRUG TRANSPORTER FUNCTION Co-chairs Ingolf Cascorbi, Kiel, Germany /
Christoph Funk, Basel Switzerland
15:30-15:55 > Christoph Funk, Basel, Switzerland - Role of drug transporters in early clinical development
15:55-16:20 > Ingolf Cascorbi, Kiel, Germany - Genetics and epigenetics of efflux transporters
16:20-16:45 > Toshihisa Ishikawa,Yokohama, Japan - Genetics and function of ABCG2 (BCRP)
16:45-17:00 > Hanan Osman-Ponchet, Sophia-Antipolis, France - Characterization and regulation of the expression of drug transporters in human skin
17:00-17:15 > Nada Božina, Zagreb, Croatia - ABCG2 polymorphism as a risk factor for developing adverse drug reactions in patients taking atorvastatin: a case-control study
17:15-17:30 > Sabina Semiz,Sarajevo, Bosnia and Herzegovina - Pharmacogenomic Variations and Metformin Response
15:30-16:30 WORKSHOP 2
16:30-18:00 TEVA Repositioning old drugs
for new indications by use of personalised and genomics approaches
Chair: Iris Grossman, Tel Aviv, Israel
16:30-16:40 > Iris Grossman, Tel Aviv, Israel - Introduction16:40-17:00 > P. Craig, Palo Alto, USA - Drug Repositioning
in the Era of Personalised Medicine17:00-17:20 > G. Peolmans, Nijmegen, The Netherlands17:20-17:40 > TBC17:40-18:00 > Markus Paulmichl, Salzburg, Austria -
The regulator point of view
17:30-18:30 SELECTED POSTER PRESENTATIONS ON DRUG TRANSPORTERS & SELECTED POSTER PRESENTATIONS
18:30-20:00 GET TOGETHER – Welcome Cocktail and Posters’ Visit by the Poster Committee
Thursday 8 October 201508:30-10:30 PERSONALIZED IMMUNOSUPPRESSION Co-chairs: Michael Oellerich, Goettingen, Germany / András Falus, Budapest, Hungary
08:30-08:55 > András Falus, Budapest, Hungary - Immunogenomics: toward the future trend of “intelligent” vaccines08:55-09:20 > Pierre Marquet, Limoges, France - Pharmacogenetics of mTOR inhibitors09:20-09:45 > Michael Oellerich, Goettingen, Germany - Biomarkers for personalized immunosuppression09:45-10:10 > Matthew Albert, Paris, France - Immunotest for personalized medicine10:10-10:30 > Samer Khaled, Duarte, USA - The influence of drug absorption, distribution, metabolism and excretion (ADME)
genomic variants on tacrolimus and sirolimus blood levels in the setting of Graft Versus Host Disease (GVHD) prophylaxis
10:30-11:00 Break
11:00-13:00 PHARMACOGENOMICS OF CARDIOVASCULAR AND ANTIDIABETIC DRUGS Co-chairs: Gabor Kovacs, Pecs, Hungary / Jaroslav Hubacek, Prague, Czech Rep
11:00-11:25 > Jaroslav Hubacek, Prague, Czech Rep - Pharmacogenetics of statin treatment efficacy and statin adverse effects11:25-11:50 > Ivan Tkac, Bratislavia, Slovakia - Pharmacogenomics of Oral Antidiabetic Drugs11:50-12:15 > György Pfliegler, Debrecen, Hungary - Personalized approach to patients with bleeding or thrombotic disorders12:15-12:40 > Sanja Stankovic, Belgrade, Serbia - Gene Polymorphisms, Platelet Reactivity, and the RISK-PCI Score
in Predicting MACE in STEMI Patients: Cost-effectiveness Analysis12:40-13:00 > Georgia Ragia, Alexandroupolis, Greece - Factors that affect acenocoumarol dosing requirements: analysis
of the Greek population recruited in European Pharmacogenetics of Anticoagulant Therapy (EU-PACT) trial
13:15-14:15 Lunch Break – Posters’ Visit
17:15-18:15 ORAL PRESENTATION AND SELECTED POSTER DISCUSSIONS > Meliha Koldemir Gunduz, Izmir, Turkey - The effects of glipizide on adipogenesis related gene expressions
by using impedance-cell based label free technology in mature adipocytes > Agnes F. Semsei, Budapest, Hungary - Anthracycline cardiotoxicity in childhood acute lymphoblastic leukemia
20:00 AWARD DINNER
14:15-15:15 WORKSHOP 3 Pharmacogenomics data treatment
and software for interpretation Coodinator: Houda Hachad, Bellevue, WA, USA
> Houda Hachad, Bellevue, WA, USA > Don Rule, Bellevue, WA, USA > Ana Sabater-Sales, Barcelona, Spain -
g-Nomic®: the tool for practical application of pharmacogenetics
> Oskari Huiskala, Abomics Oy, Finland - The use of advance information technology in implementing pharmacogenomics into clinical practice
14:15-15:15 WORKSHOP 4 - ILLUMINA
15:15-15:45 Break
15:45-17:15 THE PHARMACOGENOMICS OF ASTHMA TREATMENT
Co-chairs: Vangelis Manolopoulos, Alexandroupolis, Greece / Sabina Semiz, Sarajevo, Bosnia and Herzegovina
15:45-16:10 > Anke-Hilse Maitland van der Zee, Utrecht,
The Netherlands 16:10-16:35 > Somnath Mukhopadhyay, Brighton, United Kingdom 16:35-17:00 > Ildikó Horváth, Budapest, Hungary17:00-17:15 > Colin Palmer, Dundee, United Kingdom
15:45-17:15 GENOMICS OF VEGF AND DISEASES PREDICTION Co-chairs: Sophie Visvikis-Siest, Nancy, France /
John Lamont, Co Antrim, United Kingdom
15:45-16:05 > Sophie Visvikis-Siest, Nancy, France - The VEGF clinical implementation pathway
16:05-16:25 > Marc Rancier, Luxembourg - VEGF Genomics in clinical Endocrinology
16:25-16:50 > Helena Murray, Co Antrim, United Kingdom - Specificity of VEGF bio markers
16:50-17:15 > Behrooz Alizadeh, Groningen, The Netherlands
Friday 9 October 201508:30-10:00 PHARMACOGENOMICS IN PAIN TREATMENT Co-chairs: Adrian Lleren, Badajoz, Spain / Beata Sperlagh, Budapest, Hungary
08:30-08:45 > Adrian Llerena, Badajoz, Spain - Introduction08:45-09:05 > György Bagdy, Budapest, Hungary - Genomics of pain and comorbid disorders09:05-09:25 > Ana Peiró, Alicante, Spain - Pharmacogenectics and individualizing drug treatment in chronic pain09:25-09:45 > Alain Eschalier, Clermont-Ferrand, France - Analgesic effect of paracetamol: a new insightor Paracetamol,
a centrally-acting analgesic09:45-10:00 > Frédéric Libert, Clermont-Ferrand, France - Epigenetic regulations and neuropathic pains
10:00-10:30 Break
10:30-12:30 PERSONALIZING TREATMENT STRATEGIES IN ONCO-HEMATOLOGY Co-chairs: Marc Ansari, Geneva, Switzerland / József Timar, Budapest, Hungary
10:30-10:40 > Marc Ansari, Geneva, Switzerland - Introduction10:55-11:20 > József Timar, Budapest, Hungary - The present of personalized medicine: update on oncology11:20-11:45 > Céline Pallaud, Basel, Switzerland - Tyrosine kinase inhibitor in oncology11:45-12:10 > Joseph Ciccolini, Marseille, France - Pharmacogenetics of myelodysplastic syndromes: applications, limits and perspectives12:10-12:30 > TBC
12:30-13:30 Lunch Break
14:00-15:30 TOWARD PRACTICAL APPLICATION OF BIG DATA AND DIGITAL HEALTH FOR PERSONALIZED MEDICINE: REVOLUTION IS NOW
Co-chairs: Patrice Denèfle, Paris, France / Cyril Grospiron, Paris, France
14:00-14:15 > Patrice Denèfle, Institut Roche, France / Cyril Grospiron, Umanlife, France - Introduction14:15-14-40 > Uwe Diegel, Paris, France - The Impact of Digital Health as a tool for Clinical Research14:40-15-05 > Scott Kahn, Illumina, USA 15:05-15-30 > Andreas Posch, Siemens Healthcare, Erlangen, Germany - Patient-specific disease modeling for therapy decision support
15:30-18:00 CLINICAL IMPLEMENTATION OF PHARMACOGENOMICS DATA Co-chairs: Adrian Llerena, Badajoz, Spain / Ron van Schaik, Rotterdam, The Netherlands /
Maria Judit Molnar, Budapest, Hungary With the participation of general practitioners, young clinicians, the ESPT board members and specialised colleagues,
the speakers of the big data session and specialised software translational companies
15:20-15:35 Introduction > Ron van Schaik, Rotterdam, The Netherlands - The EuPIC initiative - Pre-emptive pharmacogenomics
Targeted Cancer therapy15:35-15:55 > Paolo Marchetti, Roma, Italy 15:55-16:15 > Bernard Courtieu, Evry, France - Genomic signature of specific tumors16:15-16:25 Discussion between clinicians and specialists
Neurodegenerative diseases 16:25-16:45 > Marie Judit Molnar, Budapest, Hungary - Mitochondrial disorders in brain disease16:45-17:05 > TBC - Pharmacogenomics and Personalised Medicine in Alzheimer disease 17:05-17:10 Discussion between clinicians and specialists
General discussion and Closing remarks > Adrian Llerena, Badajoz, Spain - Relevance of European Drug Regulation for Clinical Implementation and all participants
FULL REGISTRATIONBefore July 15
After July 15
Regular registration 450 € 600 €
ESPT Members registration 400 € 500 €
Congress dinner 60 € 60 €
STUDENTS REGISTRATIONBefore July 15
Before July 15
Regular registration 170 € 200 €
ESPT Members registration 150 € 170 €
Congress dinner 60 € 60 €
CLINICIANS REGISTRATION FOR THE LAST DAY
100 € 120 €
Registration fee includes participation to the whole congress, lunches and coffee breaks.
Registrations : general information and cancelation policiesThe final deadline for pre-registration is the 15th of September 2015. Com&Co must be notified of any cancellation in writing.
• Cancellation before the 15th of August 2015 : refunds less 10% (administrative charge).• Cancellation after the 15th of August 2015 : no refund will be given.
No-shows at the congress will be charged the full fee.
Registration fees
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