PROGRAM NanoDay@Penn

October 28, 2015

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The Nano/Bio Interface Center of the University of Pennsylvania sponsors a day of education and outreach programs for the Penn community as well as for regional high schools and neighbors. Activities include exhibits and demonstrations, laboratory tours, a research poster session, videos on nanoscale science, and a science fair featuring high school research projects. The day culminates with an NBIC awards program featuring a prominent keynote speaker.

OVERVIEW: Schedule of Events for Wednesday, October 28, 2015

All events are open to the public except for the High School group NanoTours. Additional details for the program are presented after the Schedule Overview. A map is on the final page of the program.

9:30 – 9:50 AM

NanoDay Opening – Introduction to some exciting topics in nanotechnology

Skirkanich Hall, Berger Auditorium and Towne Hall Room 225, Raisler Lounge

What’s so big & hot about nano? Graduate students introduce some key concepts and cool applications of nano-scale science.

10:00 AM – 2:00 PM

NanoDay Activities – Learn more about the Nano Sciences

Exhibits and Demos: Explore exhibits and demonstrations highlighting nanoscale science and engineering presented by NBIC research groups. Singh Center, 1st Floor

Multimedia Presentation: Learn about exciting new discoveries from nanoscale researchers in physics, chemistry, physiology and engineering from this ongoing, big screen show. Levine Hall, Lobby and Singh Center, 1st Floor

High School Science Fair Research Projects: See posters and displays of research conducted by regional high school students. Displays will be available for viewing from 10 AM – 2 PM. To interact with the high school students about their work, visit the Science Fair during the judging, which will run from 12:30 PM – 2 PM. Levine Hall, Lobby

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NanoTours and special college admission programs for visiting high school groups (pre-arranged; not open to the public)

2:45 – 3:30 PM

High School Science Research Awards Ceremony

Singh Center, Glandt Forum

Winners from the High School Science Fair Research Projects will be recognized (judging runs from 12:30 PM – 2 PM in Levine Lobby).

4:00 – 5:30 PM

Keynote Address and Graduate Student Awards

Krishna P. Singh Center for Nanotechnology, The Glandt Forum (3rd Floor)

Illuminating biology at the nanoscale with single-molecule and super-resolution fluorescence microscopy

Xiaowei Zhuang, PhD, Keynote Speaker & 10th Annual NBIC Research Excellence Award

Nanoelectromechanical switches for low-power computing Frank Streller, NBIC Graduate Student Research Award

Graduate Student and Post-doctoral Image Awards

Scientific: (Justin) Hai Zhu, Materials Science and Engineering, Scanning electron microscope image of 3D plasmonic nanoantenna arrays Artistic: John Cortes and Keivan Davami, PhD, Mechanical Engineering and Applied Mechanics, Forest of vertical graphene sheets, also known as carbon nanowalls, grown on a copper substrate Animation: Martin Haase, PhD, Chemical and Biomolecular Engineering, Solvent Transfer Induced Phase Separation (STRIPS) in action

5:30 – 6:30 PM

Reception

Krishna P. Singh Center for Nanotechnology, Lobby

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10 AM – 2 PM Nanoscience Exhibits and Demos

Explore exhibits and demonstrations highlighting nanoscale science and engineering presented by NBIC research groups. Singh Center, 1st Floor

Nanoscale Quantum Engineering Bassett Group http://nanoquant.seas.upenn.edu/

Nanotribology: Friction at the Nanoscale Carpick Group http://carpick.seas.upenn.edu/ Designing Proteins for Energy Applications Discher/Dutton Lab http://www.med.upenn.edu/duttonlab/people.html Gold Nanoparticle Synthesis Dmochowski Group http://dmochowskigroup.chem.upenn.edu/ DNA Sequencing with Nanopores Drndic Group http://www.physics.upenn.edu/drndicgroup/ Nano thick Glasses and their Crystallization Fakhraai Group http://fakhraaigroup.chem.upenn.edu/index.html Nano Sensors Johnson Group http://www.lrsm.upenn.edu/~nanophys/

Interacting with Nanomaterials Murray Group https://sites.sas.upenn.edu/cbmurray/

LCDs, Polarizers, Gummy Capsules, Nano Food Nano/Bio Interface Center http://www.nanotech.upenn.edu/

Adhesion and Roughness Turner Group http://turner.seas.upenn.edu/ Photo-Origami & Shape-Memory Polymers Winey Group http://winey.seas.upenn.edu/

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10 AM – 2 PM High School Science Fair Research Projects

See posters and displays of research conducted by regional high school students. Displays will be available for viewing from 10 AM – 2 PM. Levine Hall, Lobby

To interact with the high school students about their work, visit the Science Fair during the judging, which will run from 12:30 PM – 1:50 PM in Levine Hall, Lobby. Awards will be given at 2:45 PM. Singh Center, Glandt Forum

Grade 10

Dominic Adamo Souderton Area High School Fish Take Flight

Julianna Byrne Marine Academy of Technology and Environmental Science Fire Durability of Finger-Jointed Trusses versus Metal Gusset Plate Trusses Srisa Changolkar Julia R. Masterman School An Investigation Into Hydrogen Peroxide Detoxification Through Catalase Activity Among Various Foods Lily Day Emmaus High School Fabric Softeners and the Flame Resistancy of Children's Pajamas Michael Grantham Marine Academy of Technology and Environmental Science Generating Random Numbers Using Social Media

Spencer Hoffman Hoffman Homeschool Recovering Heat Energy by Adding Thermoelectric Coolers to Solar Panels Sumedha Kanthamneni Parkland High School Skin and Moisturizers Dima Khalil Emmaus High School Denaturing Proteins with Heat, Acids and Bases, Organic Compounds and Heavy Metals

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James Kim Parkland High School The Effect of Bioflavonoids on Various Aspects of Health in Drosophila Melanogaster Sahas Kurumety Methacton High School Lighting Up the World, One Bottle at a Time Vikram Pandian Parkland High School Measuring and GeoMapping Ambient RF Energy for Battery Free Applications Achyut Reddy Methacton High School Visualizing Homology Using Computers Matthew Siracusa Devon Preparatory Real-Time Asbestos Detection

Grade 11

Christian Albert Philadelphia Academy Charter High School Optimizing Solar Panels

Jacob Bauldock Kids for Chemistry The Effect of Ion Diffusion on the Electrical Conductivity in an Electrochemical Cell

Emily Cheng Methacton High School Development of a NGS Assay for Cancer Screening Using Methylated DNA Biomarkers

Kian Jamasbi Germantown Academy Water as Solvent for High Molecular Weight Acrylic Polymer Sagar Maheshwari Unionville High School Data Mining Kinase-Domain Cancer Mutations to Enhance Cancer Research

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Gavin Rees Germantown Academy Driving a 3D-printed Exoskeleton with Nylon Artificial Muscles

Mike Rhodes Avon Grove High School The Effect of Environment on Microbial Fuel Cells Alexis Schneider Upper Dublin High School Examining the Effects of Progesterone on Neonatal Traumatic Brain Injury

Carina Tse Methacton High School Nano-Engineering Chloroplasts with Carbon Nanotubes for Ex-Vivo Photosynthesis Will Watkins Central Bucks High School West

Numerical Simulation & Chemical Synthesis of High-Index Metallic Nanostrutures

Jacob Yatvitskiy High Technology High School Uniqueness of Human Voice Frequency Spectra Grade 12

Ariana Belton Rancocas Valley Regional High School Developing a Control Algorithm for a Smart Sensor Modulator to Establish Communication between a Continuous Glucose Monitoring Device and an Insulin Pump Kerri Diamond Souderton High School The Hive Comparison: The Possible Benefit of Diversified Pollinators Julia Fischer Council Rock High School North An Exploratory Study on the Differentiation between Conventionally and Organically Grown Commercial Produce Using Nuclear Magnetic Resonance Atharv Gupte Parkland High School Enhancing Thermal Dissipation of Processors through Plasma Etching of Multiwalled Carbon Nanotubes

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Nate Hoffman Hoffman Homeschool Component Locator: A Step Toward Automated Car Repair

Himavath Jois Wissahickon High School Effect of Winglet Angle on Efficiency of Wing

Kunal Singh High Technology High School Developing a Face Recognizer Application for the Visually Impaired on the Google Glass Shika Veera Parkland High School Effects of Allura Red AC on Apoptosis of DT40 Cells through Expression of Mitochondrial Stress Proteins AIF and ENDO-G

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4:00-5:30 PM Keynote Address and Graduate Student Awards

Krishna P. Singh Center for Nanotechnology, The Glandt Forum (3rd Floor)

Presentation by the Keynote Speaker & 10th Annual NBIC Research Excellence Award

Illuminating biology at the nanoscale with single-molecule and super-resolution fluorescence microscopy

Xiaowei Zhuang, PhD, Harvard University and Howard Hughes Medical Institute Dissecting the inner workings of a cell requires imaging methods with molecular specificity, molecular-scale resolution, and dynamic imaging capability such that molecular interactions inside the cell can be directly visualized. Fluorescence microscopy is a powerful imaging modality for investigating cells largely owning to its molecular specificity and dynamic imaging capability. However, the diffraction-limited resolution of light microscopy is substantially larger than molecular length scales in cells, making many sub-cellular structures difficult to resolve. We developed a super-resolution fluorescence microscopy method, stochastic optical reconstruction microscopy (STORM), which overcomes the diffraction limit by using photo-switchable fluorescent probes to temporally separate the spatially overlapping images of individual molecules. This approach has allowed multicolor and three-dimensional imaging of living cells with nanometer-scale resolution and enabled discoveries of novel sub-cellular structures. In this talk, I will discuss the technological advances of STORM and recent biological discoveries enabled by STORM. I will also describe a single-cell transcriptome imaging method that we recently developed, which allows in situ transcriptomic analysis in a spatially resolved manner in single cells.

NBIC Graduate Student Research Award

Nanoelectromechanical switches for low-power computing

Frank Streller, PhD Candidate, Dept. of Materials Science and Engineering, University of Pennsylvania Nanoelectromechanical (NEM) switches are a candidate to replace transistors due to their low

power consumption. However, the reliability of the contact interface limits their commercialization, as the electrical contact must physically open and close up to a 1015 times without failing due to adhesion (by sticking shut) or contamination (reducing switch conductivity). These interfacial failure mechanisms are not well understood, and materials that avoid them have not yet been demonstrated. This talk presents a novel, high-throughput contact material screening method for NEM contact materials based on atomic force microscopy (AFM) that enables billions of contact cycles in laboratory timeframes for arbitrary material pairs. Additionally, the development of platinum silicide (PtxSi) as a promising NEM switch contact material is presented. Using controlled solid-state diffusion of thin films of amorphous silicon and platinum, PtxSi was formed over a range of stoichiometries (1≤x≤3). The platinum-rich silicide phase (Pt3Si) may be a particularly ideal contact material for NEM switches due to its combination of mechanical robustness and metal-like conductivity with contamination resistance.

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Graduate Student and Post-doctoral Image Awards

Scientific: (Justin) Hai Zhu, Materials Science and Engineering, Scanning electron microscope image of 3D plasmonic nanoantenna arrays

Artistic: John Cortes and Keivan Davami, PhD, Mechanical

Engineering and Applied Mechanics, Forest of vertical graphene sheets, also known as carbon nanowalls, grown on a copper substrate

Animation: Martin Haase, PhD, Chemical and Biomolecular Engineering, Solvent Transfer Induced Phase Separation (STRIPS) in action

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A big thank you to the many volunteers who donated their time and expertise! The 2015 NanoDay@Penn could not happen without them.

NanoDay@Penn Sponsors

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Buildings with NanoDay@Penn activities are marked in Red. Specific locations are detailed within the program.

Nano/Bio Interface Center at the University of Pennsylvania is a Nanoscale Science and Engineering Center (NSEC) bringing together researchers from the Schools of Engineering and Applied Science; Arts and Sciences; and Medicine. The NBIC exploits Penn's internationally recognized strengths in design of molecular function and quantification of individual molecules. The Center unites investigators from ten departments to provide, not only new directions for the life sciences, but also for engineering in a two-way flow essential to fully realizing the benefits of nano-biotechnology.

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