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PROGRAM

The 8th AIC on Health and Life Sciences

The Annual International Conference 2018 Syiah Kuala University

“Connecting the World through Innovation and Sustainable Development”

Banda Aceh, Aceh, Indonesia September 12-14, 2018

i The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Table of Content

Table of Content................................................................................................................................. i

Advisory Board ................................................................................................................................. vi

Organizing Committee................................................................................................................... vii

Scientific Committee ..................................................................................................................... viii

Welcome Speech from Rector of Syiah Kuala University ....................................................... ix

Welcome Speech from General Chair .......................................................................................... xi

Keynote Speaker .............................................................................................................................. xii

Invited Speaker 1............................................................................................................................ xiv

Invited Speaker 2............................................................................................................................ xvi

Guidelines ...................................................................................................................................... xviii

Maps and Location ......................................................................................................................... xix

AAC Auditorium Venue Map ........................................................................................................ xx

Parallel Sessions Venue Map ....................................................................................................... xxi

Technical Program Schedule ...................................................................................................... xxii

Parallel Sessions ........................................................................................................................... xxiv

THE POTENTIAL OF SILVER NANOPARTICLES TO CONTROL Rhizoctonia solani (AG3-

PT) GROWTH IN VITRO .................................................................................................................... 1

Hartati Oktarina1*, Lidija Siller2, James Woodhall3, and Ian Singleton4 ............................ 1

NURSES’ PREPAREDNESS IN EMERGENCY MANAGEMENT SYSTEM ON DISASTER ........... 2

Cut Husna1*, Teuku Tahlil2, Hajjul Kamil3, Mustanir4, Rizka Hayaturrahmi5 .................. 2

UTILIZION OF ETHANOLIC Eucalyptus urophylla LEAF EXTRACT FOR MORTALITY AND

BEHAVIOUR LARVAE OF Culex quinquefasciatus AS BIOINSECTICIDE ............................... 3

Safrida Safrida1*, Devi Syafrianti1, Miftahul Jannah1, Musri Musman2, Muhammad

Iwan Kurniawan1 ........................................................................................................................... 3

SENSORY AND PHYSICAL QUALITY ASSESSMENT OF SIE REUBOH (COOKED MEAT- AN

ACEHNESE TRADITIONAL CUISINE) ............................................................................................. 4

Dian Hasni1*, Novia Mehra Erfiza1, Cut Nilda1 and Muhammad Faiz1 ............................... 4

EVALUATION OF ANTIOXIDANT, ANTIBACTERIAL POTENTIAL, NUTRITION VALUE

AND ACUTE TOXICITY STUDY OF LIBYAN DATE PALM POLLEN (DPP) ............................... 5

Ramin Basher Ashour1, Abdulrzag A. Auzi1, Rabya A. Lahmer2* ....................................... 5

QUALITY OF WHEAT GENOTYPE DEWATA GROWTH UNDER WET TROPICAL CLIMATE

OF INDONESIA ................................................................................................................................... 6

M I Sulaiman1*, I Syahroni1, R Andini2 and L Hakim3 ............................................................. 6

TOXICITY SUB-CRONIC ETHANOLIC EXTRACT OF MALAKA (Phyllanthus emblica)

LEAVES ON LIVER FUNCTION OF MICE (Musmusculus) BE REVIEWED FROM SERUM

BILIRUBIN LEVEL................................................................................................................................ 7

Nuzul Asmilia1,2, Yudha Fahrimal3, Mahdi Abrar4, Rinidar5 ................................................. 7

AMINO ACID AND SENSORY PROFILE OF KOPI LUWAK (CIVET COFFEE)............................ 8

Murna Muzaifa1,2*, Dian Hasni2, Dewi Yunita2, Febriani3, Anshar Patria2

, Amhar

Abubakar4 ....................................................................................................................................... 8

PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS, PORCINE

CIRCOVIRUS AND Pasteurella multocida CO-INFECTION IN PIGS ......................................... 9

Chanathip Thammakarn1*, Pham Hoang Son Hung2 and Sirichai Eardmusic3 ................ 9

PHYSICAL PROPERTIES OF COMPOSITE BIODEGRADABLE FILMS BASED ON TUNA-SKIN

GELATIN AND CHITOSAN ............................................................................................................. 10

Normalina Arpi1, Fahrizal Fahrizal1, Syarifah Rohaya1* ..................................................... 10

ii The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

CAN TRICHODERMA PELLETS SUPPRESSING THE DEVELOPMENT OF Synchytrium

pogostemonis DISEASE IN PATCHOULI PLANTS? .................................................................... 11

Rina Sriwati1*, Tjut Chamzurni1, Elly Kusumawati2,Tiara Kusuma Pertiwi2................... 11

ISOLATION AND IDENTIFICATION OF ENDOPHYTIC FUNGUS Fusarium sp FROM

AGARWOOD (Aquilaria sp) POPULATION ORIGINATED FROM THE FOREST OF ACEH

TAMIANG DISTRICT, INDONESIA ................................................................................................ 12

Zulfendi1,2, Rinaldi Idroes3 and Khairan4* ............................................................................... 12

HETEROSIS AND HETEROBELTIOSIS OF AGRONOMIC AND YIELD TRAITS IN THAI

UPLAND RICE HYBRIDS ................................................................................................................. 13

Wulan Kumala Sari1,2, Charassri Nualsri3, Nattapon Junsawang4 and Watcharin

Soonsuwon3* ................................................................................................................................. 13

A PRELIMINARY STUDY: ANTIHYPERGLYCEMIC ACTIVITIES OF Phaleria macrocarpa

AND SITAGLIPTIN, AN INHIBITOR OF DIPEPTIDYL PEPTIDASE (DPP-IV) .......................... 14

Suryawati Suryawati1*, Putri Indini 2, Zulfitri Zulfitri3, Vera Dewi Mulia4 ....................... 14

ANTENATAL CARE AND IRON DEFICIENCY ANEMIA ............................................................ 15

Darmawati1*, Teuku Tahlil2, Toungku Nizwan Siregar3, Hajjul Kamil 4, Fithria5, and

Masyithah Audina6 ...................................................................................................................... 15

PREVENT AND TREAT EPISTAXIS WITH BIOFLAVANOIDS: A REVIEW ............................... 16

Teuku Husni T.R1 ........................................................................................................................ 16

SUBJECTIVE WORK FATIGUE AND RELATED FACTORS ON SILUNGKANG WEAVERS.... 17

Aria Gusti1* and Tria Ananda1 ................................................................................................... 17

PSYCHOLOGICAL WELL-BEING AMONG SMOKERS’ ADOLESCENCE ................................... 18

Fithria1*, Teuku Tahlil2, Adlim3, Syarifah Rauzatul Jannah4, Darmawati5, Cut Dirna

Armanda6 ...................................................................................................................................... 18

DIVERSITY AND DISTRIBUTION OF FISHES IN KRUENG SABEE RIVER, ACEH JAYA,

INDONESIA........................................................................................................................................ 19

Muhammad Nasir1,2*, Farah Aulia Putri1, Raudhatul Ulfa1, Mardianti1, Firdus Firdus1 ,

Munira3, Zainal Abidin Muchlisin4, Saiful5 and Suhendrayatna6 ...................................... 19

ANTIBACTERIAL ACTIVITY OF Magnolia alba FLOWERS EXTRACTS ON Staphylococcus

epidermidis AND Staphylococcus aureus ................................................................................... 20

Khairan Khairan1*, Soraya Septiya1, Murniana2 .................................................................... 20

COMBINED EFFECT OF STREPTOMYCIN AND SWEET ORANGE ESSENTIAL OIL TO

MEMBRANE AND ACROSOME INTEGRITY BOER GOAT FROZEN SEMEN ........................... 21

Sukma Aditya Sitepu1* and Julia Marisa2 ............................................................................... 21

POTENCY ANTIOXIDANT COMPOUNDS OF INDIAN GOOSEBERRY (Phyllanthus emblica)

LEAVES AS HERBAL TEA ................................................................................................................ 22

Mailisa1*, Cut Meliana1,Cut Maysura Hanum2, Yanti Meldasari Lubis1, Novia Mehra

Erfiza1, and Heru Prono Widayat1 ............................................................................................ 22

TAXONOMY OF THE GENUS Longipeditermes HOLMGREN (TERMITIDAE:

NASUTITERMITINAE) FROM THE SUNDA REGION, SOUTHEAST ASIA ............................... 23

Syaukani Syaukani1*

, Graham J Thompson2, Seiki Yamane3, Ahmad Sofiman

Othman4

, Samingan Samingan5, Djufri Djufri

5, Muhammad Ali5

, Hasanuddin

Hasanuddin5

, Husni Husni6 ....................................................................................................... 23

DIVERSITY OF ARTHROPODS AT THE ARABICA COFFEE PLANTATION IN ATANG

JUNGKET VILLAGE, ACEH TENGAH REGENCY ......................................................................... 24

Muhammad Sayuthi1*, Hasnah1, Alfian Rusdy1, Susanna1, Auliani1 ................................. 24

DENSITY FIGURE OF Aedes spp LARVAE IN JEULINGKE VILLAGE SYIAH KUALA

SUBDISTRICT BANDA ACEH ......................................................................................................... 25

Farida Athaillah1* ......................................................................................................................... 25

iii The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

COMPARISON OF COX MODELS IN DETECTING FACTORS AFFECTING HEALING RATE

OF DENGUE HEMORRHAGIC FEVER............................................................................................ 26

Miftahuddin1* and Inas Salsabila1 ............................................................................................ 26

PREPARATION OF 3-DIMETHYLCARBAMOYL EMODIN AND ITS CYTOTOXIC

EVALUATION AGAINST HepG2 CELL LINES ............................................................................. 27

Firdayani1*, Churiyah1 and Billy Witanto2............................................................................... 27

REMEDIAL LEARNING BASED SCAFFOLDING FOR STUDENTS INCREASE LOW ............... 28

Rizqa Rahmati1*, Anwar1, Anizar Ahmad3 ............................................................................. 28

ANTIHYPERGLYCEMIC POTENTIAL OF HELMINTHOSTACHYS ZEYLANICA LEAVES

EXTRACT IN DIABETIC RATS ....................................................................................................... 29

Erlidawati Erlidawati1, Musri Musman1, Safrida Safrida1* ................................................. 29

IMPACTS OF COFFEE VARIETIES AND PROCESSING PRACTICES ON THE PHYSICAL AND

SENSORY CHARACTERISTIC OF GAYO ARABICA SPECIALTY COFFEE .............................. 30

Yusya' Abubakar1*, Dian Hasni1, Murna Muzaifa1, Heru Prono Widayat1, Ismail

Sulaiman2, Mahdi Mahdi3 ........................................................................................................... 30

THE EFFECT OF TINOSPORA CRISPA ON ANTI OXIDANT STATUS IN STREPTOZOTOCIN

INDUCED DIABETIC RATS ............................................................................................................. 31

Sarah Firdausa 1, Maung Maung Cho2, Khin Maung Maung2, Nilar Aung2, Norsidah

Kuzaifah2 ....................................................................................................................................... 31

OPTIMIZATION OF MINIMAL MEDIUM FORMULATION TO ENHANCE ACTIVITY OF IOX

(IODIDE-OXIDATION ENZYME) SYSTEM AS A NOVEL ANTIMICROBIAL-BASED ENZYME

............................................................................................................................................................. 32

Tri Yuliana1, Seigo Amachi2, Efri Mardawati3 ......................................................................... 32

UTILIZATION OF LOCAL FISH MEAL WASTE AS A SUBSTITUTE PROTEIN SOURCE TO

REDUCE THE COST OF BROILER DIET........................................................................................ 33

Aman Yaman1*.............................................................................................................................. 33

PATOBIOLOGY OF CHRONIC PAIN; WHAT IS THE DIFFERENT FROM PATOBIOLOGY OF

ACUTE PAIN? .................................................................................................................................... 34

Endang Mutiawati ....................................................................................................................... 34

PHYSICOCHEMICAL CHARACTERIZATION OF OIL FROM ROATED COFFEE .................... 35

Sukma Rizki Ariga1*, Yuliani Aisyah1, Anshar Patria1, Normalina Arpi1 and Dewi

Yunita1 ........................................................................................................................................... 35

POMEGRANATE PEEL POTENCY AS PREVENTIVE AGENT OF RHEUMATOID ARTHRITIS

............................................................................................................................................................. 36

Doti Wahyuningsih1*, Annisa Amilia2, Asri Cahyaningrum2, Laili Cinthianur

Kurniasari2, Meilano Setiawan Amiruddin2 ........................................................................... 36

THE ROLE OF PLANT GENETIC RESOURCES IN ENCOUNTERING CLIMATE CHANGE

CHALLENGE ...................................................................................................................................... 37

Rita Andini1*, M. Ikhsan Sulaiman2, Evan Febriansyah1, Ashabul Anhar1 ...................... 37

SEX AND BODY CONDITION ARE CORRELATED TO PREVALENCE AND PARASITIC

INTENSITY OF TREMATODE INFECTION IN ACEH CATTLE .................................................. 38

Muhammad Hambal1, Rizka Ayuni1, Henni Vanda2, Mustafa Sabri3, Farida1 ................. 38

ANALYSIS RELATIONSHIP BETWEEN PRODUCTION FACTORS WITH BUSINESS

PRODUCTION OF BROILER CHICKEN IN BERINGIN VILLAGE DELI SERDANG REGENCY

............................................................................................................................................................. 39

Julia Marisa1* and Sukma Aditya Sitepu2 ............................................................................... 39

OUTCOME CARBAPENEM-RESISTANT ENTEROBACTERIACEAE (CRE) CLINICAL

SPECIMENT ISOLATE IN ZAINOEL ABIDIN GENERAL HOSPITAL BANDA ACEH YEAR

2017.................................................................................................................................................... 40

Zinatul Hayati1*, Syamsul Rizal2, Masralena Siregar3, Wilda Mahdani1, Teuku Fadrial

Karmil4, Ridhia Putri5 ................................................................................................................. 40

iv The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

DENSITY LEVEL, GROWTH PATTERN, AND DISPERSION PATTERN OF FAUNUS ATER AT

REULENG RIVER LEUPUNG ACEH BESAR ................................................................................... 41

Rahmi Agustina1,2*, M. Ali Sarong3, Fredinan Yulianda4, Suhendrayatna5, Rahmadi6... 41

STEROID LEVEL OF REPEAT BREEDING ACEH CATTLE SYNCHRONIZED WITH PGF2Α . 42

Cut Nila Thasmi1*, Tongku Nizwan Siregar1, Sri Wahyuni2, Dwinna Aliza3, Hamdan

Hamdan, Budianto Panjaitan4, Nuzul Asmilia1, Husnurrijal Husnurrijal5 ..................... 42

THE EFFECT OF ACID AND ENZYMATIC HYDROLYSIS ON XYLITOL PRODUCTION

FROM OIL PALM EMPTY FRUIT BUNCH ..................................................................................... 43

Efri Mardawati1* ........................................................................................................................... 43

CHILDHOOD ACTIVITIES MEMORIES AMONGST HEALTHY ADULTS IN THE MODEL OF

INTERVENTION REMINISCENCE BASED SCREENING .............................................................. 44

Eva Berthy Tallutondok1* .......................................................................................................... 44

NON-INVASIVE MONITORING OF STRESS IN FEMALES CRESTED MACAQUES (Macaca

nigra): COMPARISON OF GLUCOCORTICOID LEVELS DURING CYCLING, PREGNANCY,

AND LACTATION ............................................................................................................................ 45

Gholib Gholib1, Muhammad Agil2, Iman Supriatna2, Bambang Purwantara2, Triva

Murtina Lubis1, Mulyadi Adam1, Azhar1................................................................................. 45

POTENTIAL OF WOOD-DEGRADING BASIDIOMYCETES Marasmiellus sp AND

Ganoderma lucidum IN XYLANASE ENZYME PRODUCTION AND ITS ACTIVITY USING

AGRO-INDUSTRY WASTE .............................................................................................................. 46

Tri Yuliana1*, Efri Mardawati2, Souvia Rahimah1, SON Yudiastuti3 .................................. 46

THE COMPARATION INSULIN RECEPTOR AND INSULIN RESISTANCE BETWEEN SLOW

INTERVAL TRAINING AND MODERATE CONTINOUS............................................................. 47

Yetty Machrina1, Ambrosius Purba2, Dharma Lindarto3 .................................................... 47

SENSORY EVALUATION WITH DESCRIPTIVE METHOD ON ACEH LOCAL RICE (Oryza

Sativa L.) MUTANT M6 USING GAMMA-RAY IRRADIATION ................................................... 48

Rita Hayati1*, Efendi1 and Fitri Yunita1 ................................................................................... 48

LIME LEAVES ETHANOL-EXTRACT, CAJUPUT OIL, AND ITS COMBINATION EFFECTS TO

RICE WEEVIL MORTALITY ............................................................................................................. 49

Nabiila Kaltsum Ulayya1*, Udi Tarwotjo1 and Rully Rahadian1 ......................................... 49

TOXICITY SUB-CRONIC ETHANOLIC EXTRACT OF MALAKA (PHYLLANTHUS EMBLICA)

LEAVES ON LIVER FUNCTION OF MICE (Mus musculus) BE REVIEWED FROM SERUM

BILIRUBIN LEVEL.............................................................................................................................. 50

Nuzul Asmilia1,2, Yudha Fahrimal3, Mahdi Abrar4, Rinidar5 ............................................... 50

STUDY OF FICUS LYRATA WARB FRUIT EXTRACT EFFECT ON TOXICITY,

PHYSICOCHEMICAL, AND MICROBIOLOGY PROPERTIES OF CHICKEN CARCAS ............ 51

Dwi Wahyudha Wira1* ................................................................................................................ 51

THE PROFILE OF BACTERIAL URINARY TRACT INFECTION AETIOLOGY ISOLATED

FROM HOSPITALIZED PATIENTS IN DR. ZAINOEL ABIDIN GENERAL HOSPITAL BANDA

ACEH .................................................................................................................................................. 52

Wildani Mahdani1,2*, Zinatul Hayati1,2, Ridhia Putri2, Teuku Fadrial Karmil3 .................. 52

ASSOCIATION BETWEEN RAMADAN FASTING AND GASTROESOFAGEAL REFLUX

DISEASE CLINICAL SYMPTOMS IN ACEH TAMIANG HOSPITAL ........................................... 53

Anandita Putri1* .......................................................................................................................... 53

CHEMICAL AND MICROBIOLOGICAL CHARACTERISTICS OF COCOA BEANS FROM

PIDIE DISTRICT, ACEH PROVINCE, INDONESIA ....................................................................... 54

Martina Fitri Wahyuni1*, Dewi Yunita1, Yusriana Yusriana1, Yuliani Aisyah1 ............... 54

TREATMENT OF INTRODUCTION OF LEAF FERMENTATION AND DISTILATION ON

EUCALYPTUS OIL RENDEMEN ...................................................................................................... 55

Novi Mailidarni1, Anshar Patria1, Yuliani Aisyah1 ................................................................ 55

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EFFECTS OF TYPE AND CONCENTRATION STABILIZERS ON THE CHARACTERISTICS OF

NUTMEG OIL NANOEMULSIONS PREPARED BY HIGH PRESSURE HOMOGENIZATION ... 56

Yuliani Aisyah1, Sri Haryani1, Ayu Simah Bengi1 .................................................................. 56

vi The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Advisory Board

Prof. Dr. Samsul Rizal Rector of Syiah Kuala University, Indonesia

Prof. Dr. Marwan Vice Rector I for Academic Affairs, Syiah Kuala University, Indonesia

Dr. Agussabti Vice Rector II for Financial Affairs, Syiah Kuala University, Indonesia

Dr. Alfiansyah B.C. Vice Rector III for Alumnae and Student Affairs, Syiah Kuala University, Indonesia

Dr. Hizir Vice Rector IV for Planning, Cooperation, and Community Affairs, Syiah Kuala University, Indonesia

Dr. Taufik Fuadi Abidin Head of Institute for Research and Community Services, Syiah Kuala University, Indonesia

vii The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Organizing Committee

General Chair

Dr. Heru Fahlevi, Syiah Kuala University, Indonesia

General Co-Chair

Wahyu Rinaldi, Syiah Kuala University, Indonesia

Treasurer and Finance Chair

Dr. Ira Devi Sara, Syiah Kuala University, Indonesia

Conference Chair

Dr. Dewi Yunita, Syiah Kuala University, Indonesia

Editor in-Chief

Dr. Suhartono, Syiah Kuala University, Indonesia

Website Developer

Muhammad Chandra Gunawan, Syiah Kuala University, Indonesia

viii The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Scientific Committee

Editors

Dr. Suhartono, S.Si., M.Sc., Syiah Kuala University, Indonesia

Dr. Dewi Yunita, S.TP., M.Res. Syiah Kuala University, Indonesia

Scientific Committee Member

Dr. Ronny Horax (University of Arkansas, USA)

Dr. Diirisa Mugampoza (Kyambogo University, Uganda)

Dr. Vijith S. Jayamanne (University of Ruhuna, Sri Lanka)

Dr. Rabya A. Lahmer (University of Tripoli, Libya)

Prof. Dr. Iskandar Siregar (Institut Pertanian Bogor, Indonesia)

Dr. Achmad Farajallah (Institut Pertanian Bogor, Indonesia)

Prof. Dr. Anja Meryandini, MS. (Institut Pertanian Bogor, Indonesia)

Dr. Rika Indri Astuti, M.Si. (Institut Pertanian Bogor, Indonesia)

Dr. rer. nat. Anto Budiharjo, S.Si., M.Biotech. (Universitas Diponegoro, Indonesia)

Dr. Puji Rianti, S.Si., M.Si. (Institut Pertanian Bogor, Indonesia)

Dr. Andi Yasmon, S.Pi., M.Biomed. (Universitas Indonesia, Indonesia)

Prof. Ocky Karna Radjasa (Ristekdikti)

Ir. Akhmad Zubaidi, MAgSc., PhD (Universitas Mataram, Indonesia)

Dr. rer. nat. Adi Nur Cahyono (Universitas Negeri Semarang, Indonesia)

Prof. Dr. Muchlisin Z.A, S.Pi, M.Sc. (Universitas Syiah Kuala, Indonesia)

Prof. Dr. Ir. Samadi, M.Sc. (Universitas Syiah Kuala, Indonesia)

Dr. Suhartono, S.Si., M.Sc. (Universitas Syiah Kuala, Indonesia)

Dr. Dewi Yunita, S.TP., M.Res. (Universitas Syiah Kuala, Indonesia)

Dr. Ir. Jauharlina, M. Sc. (Universitas Syiah Kuala, Indonesia)

Dr. -Ing. Sri Haryani, M. Sc. (Universitas Syiah Kuala, Indonesia)

drh. Teuku Reza Ferasyi, M.Sc., Ph.D (Universitas Syiah Kuala, Indonesia)

Dr. Essy Harnelly, S.Si, M.Si. (Universitas Syiah Kuala, Indonesia)

Dr. Alia Rizki, S.Si., M.Sc. (Universitas Syiah Kuala, Indonesia)

Ns. Suryane S. Susanti, MA., Ph.D (Universitas Syiah Kuala, Indonesia)

Dr. Hartati Oktarina, SP., M.Sc. (Universitas Syiah Kuala, Indonesia)

Dr. Syaukani, S.Si., M.Sc. (Universitas Syiah Kuala, Indonesia)

dr. Nur Wahyuniati, M.Imun. (Universitas Syiah Kuala, Indonesia)

dr.Tristia Rinanda, M.Si (Universitas Syiah Kuala, Indonesia)

Dian Hasni, S.TP., M.Sc. (Universitas Syiah Kuala, Indonesia)

Dony Hermanto, S.Si., M.Biomed (Universitas Indonesia, Indonesia)

ix The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Welcome Speech from Rector of Syiah Kuala University Assalamualaikum Wa Rahmatullahi Wa Barakatuh,

In the name of Allah, the Most Beneficent and the Most Merciful, may peace, mercy, and blessings of Allah be upon you. Dear colleagues, professors, lecturers, researchers, ladies and gentlemen. On behalf of Syiah Kuala University, I would like to express my sincere gratitude and welcome you to the 8th Annual International Conference (AIC) on Health and Life Sciences 2018. Moreover, I honorably welcome our keynote speaker, Dr. Konstantinos Gkatzionis from University of Birmingham, the United Kingdom, and our invited speakers, Dr. Berry Juliandi from Bogor Agricultural University (IPB), and Prof. Samadi from Syiah Kuala University, Indonesia. I am optimist that the 8th AIC on Health and Life Sciences 2018 is able to accomplish its goals in addressing critical research priorities in health and life sciences, as well as information and knowledge gaps in global and specific regions. This event gathers academicians, researchers, and practitioners from all over the world to discuss and share important technological, health and societal challenges, social and sciences contributions and capacities, and make recommendations for future research, practice and policy for a sustainable development. Sustainability is a strategy that drives long-term growth and effectiveness in development, either in the social sciences, science and engineering, and health and sciences fields. Therefore, encompassing technology with the society is crucial for attaining long-term sustainable development because it bears the largest potential for improvement. In this era, the digital revolution creates both new opportunities and challenges for the humankind. Society is required to transform and adapt to the new environment and situation. However, not all of us can adapt and embrace the changes. Many are left behind, and there are also those who do not receive the opportunities offered by the digital revolution. We believe that that technology, innovation and societies can facilitate sustainable development. For that matter, all academicians, researchers, and practitioners should focus their research on helping countries and people to sustain their development. Corresponding to this matter, the theme of the conference this year is “Connecting the world through innovation and sustainable development”. This conference envelops a wide range of interesting topics related to all theoretical and practical aspects in health and life sciences, but not limited to health science, veterinary science, agriculture, biotechonology, marine & Fisheries and Biodiversity. I would also like to take this opportunity to express my deep appreciation to the Advisory Board, Organizing Committee, International Scientific Committee, institutions, companies, and volunteers for their efforts to make this conference happen, and many others who have generously given help in the process. Although we try our finest to be professional, on behalf of Syiah Kuala University, please accept our sincere apologies should there be inconveniences that occur before, during, or after the event. I hope everyone have interesting and stimulating discussions in these couple of days. I sincerely pray that this

x The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

conference is a great success not only as a platform to share knowledge and experience, but also as a chance to begin continuous and productive cooperation and friendships. May God bless us all with good health to make this event a successful and enjoyable one! Best Regards, Prof. Dr. Ir. Samsul Rizal, M.Eng. Rector of Syiah Kuala University

xi The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Welcome Speech from General Chair

Assalamualaikum Wa Rahmatullahi Wa Barakatuh,

On behalf of the organizing committees, I would like to welcome all of you to Banda Aceh, Indonesia, for the the 8th Annual International Conference (AIC) as a part of the 2018 Annual International Conference (AIC) Syiah Kuala University. The AIC is an annual international conference carried out regularly by Syiah Kuala University since 2011. Therefore, we would like to express our sincere appreciation for their support to the conference. Under the theme of ”Connecting the world through innovation and suistainable development", this conference features a rich program, including Syiah Kuala University Innovation Expo 2018, a keynote speech delivered by Dr. Konstantinos Gkatzionis from University of Birmingham, the United Kingdom, and invited speeches by Dr. Berry Juliandi from Bogor Agricultural University (IPB), and Prof. Samadi from Syiah Kuala University, Indonesia. The 8th AIC on Health and Life Sciences 2018 offers a special opportunity to bring together professors, researchers and scholars around the globe, and serves as a platform to deliver innovative research results and latest trends and development in the fields of health and life sciences. The selected papers in this conference will have the opportunities to be published in The Southeast Asian Journal of Tropical Biology (BIOTROPIA) and HAYATI Journal of Biosciences (HAYATI J Biosci). BIOTROPIA is a scientific publication of the Southeast Asian Ministers of Education Organization (SEAMEO) – Southeast Asian Regional Center for Tropical Biology (BIOTROP) and indexed by SciVerse SCOPUS (Elsevier), CrossRef, DOAJ and Google Scholar. Meanwhile, HAYATI is an international peer-reviewed and open access journal that publishes papers from all area of biosciences fields such as biodiversity, biosystematics, ecology, physiology, behavior, genetics and biotechnology. HAYATI has also been indexed/registered in SCOPUS, Crossref, DOAJ, CABI, EBSCO, Agricola and ProQuest.

The conference has received 54 submitted abstracts, whereby 39 papers have been accepted by the committees for presentation. These papers on various topics are divided into 8 parallel sessions in the conference. To all members of the organizing committees, the international scientific committee, the reviewers, and the collaboration partners, we would like to thank all of them for their tremendous efforts to organize this conference successfully.

We look forward to having a successful conference, and we hope that all attendees enjoy and benefit from this conference. Best Regards, Dr. Heru Pahlevi General Chair

xii The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Keynote Speaker

FROM FOOD MICROBIOLOGICAL ANALYSIS BY CULTURE

TO THE LIBERATION OF DNA SEQUENCING AND BEYOND: DEVELOPMENTS, CHALLENGES AND FUTURE TRENDS IN

REFERENCE METHODS AND INDUSTRY STANDARDS

Konstantinos Gkatzionis1*

1School of Chemical Engineering, University of Birmingham, UK. *Corresponding author e-mail: [email protected]

Abstract

Rapid developments in sequencing technology along with falling cost brought widespread opportunities and changes in food microbiological analysis. Long term established practices and analytical ‘gold standards’, such as food analysis by culture and microbiological typing with PFGE or MLST, change or could be made redundant. The completion of the human genome draft back in 2000 required a decade of international collaboration and billions of dollars, however, nowadays bacterial genomes can be sequenced in hours for less than $100 with what is collectively termed as ‘next generation sequencing’ technology. The increasing accessibility to sequencing whole genomes and ability of laboratories to identify, and differentiate bacterial and viral strains, reform the practice and expectations in managing quality and safety in food industry. While next generation sequencing is still shaping, 3rd generation sequencing is in progress and bringing ultimate portability. Further emerging technologies such as user-friendly bioinformatics software tools, next-generation robotics, novel sensor materials and drones, start making their way to food analysis applications. While government authorities and global industries have taken initiative, the majority of food industry lacks awareness and capability to fully understand the benefits, issues and future challenges in the changes of conducting food microbiological analysis. Therefore, the lecture will attempt a review of practices and methods that underlined the industry microbiology standard up to date, recent developments that change the way of work and coming technological opportunities and challenges that are expected to shape the future. Keywords: microbiological typing, next generation sequencing, third generation sequencing, emerging technologies, bioinformatics.

xiii The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Keynote Speaker – Profile

Dr. Konstantinos “Kostas” Gkatzionis is Assistant Professor at the School of Chemical Engineering, University of Birmingham (UK) since 2013 with focus on food science. Before moving to Birmingham, he has benefited from being exposed to a number of industries, universities and cultural environments throughout his career. Kostas Gkatzionis received his Bachelor’s degree in food technology from ATEI, Thessaloniki, Greece and worked as food technologist and quality control manager in food industry. He completed his Ph.D. degree at the Division of Food Sciences, University of

Nottingham, UK, and has held appointments as a KTP associate with Pepsico (2008) and research associate with the University of Northampton (2009). Throughout his academic career, he has supervised >10 doctoral and >35 M.Sc. projects and post-doctoral researchers and is involved in teaching, at both undergraduate and post-graduate level, a variety of subjects including food safety, hygiene and management Masters.

Dr Kostas Gkatzionis’ tea ching and research take a multidisciplinary approach in applied research addressing industrial problems and challenges as well as fundamental investigations. His group investigates areas of formulation, processing, microbiology and safety. He has been involved in a number of successful research and infrastructural grants totalling ~ 4.5million euros including Horizon 2020, UK research council funding, iNETs and industry funding. Dr Kostas Gkatzionis is member of the BBSRC Peer Review Panel (subject food safety) and his academic citizenship includes links to and collaborations with Asia and Africa as well as partnerships within the EU, materialised through joint consortia, projects and consultancy with industries, academic institutions and food SMEs.

He is also a reviewer in the following international journals: Journal of Food Composition and Analysis; Food Chemistry; International Dairy Journal; Food and Bioproducts Processing; Food Processing and Preservation; Food and Bioprocess Technology; Critical Reviews in Microbiology; International Journal of Food Microbiology; Journal of Nanobiotechnology; International Food Research Journal; Food Research International; Journal of Applied Research on Medicinal and Aromatic Plants.

xiv The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Invited Speaker 1

REGULATION OF ADULT HIPPOCAMPAL NEUROGENESIS

Berry Juliandi1,2*, Taito Matsuda2, Kinichi Nakashima2

1Department of Biology, Bogor Agricultural University (IPB), Bogor 16680, Indonesia.

2Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

*Corresponding author e-mail: [email protected]

Abstract

Neurogenesis in the brain of adult mammals occurs throughout life, and has been clearly demonstrated at two locations under physiological condition: the subventricular zone (SVZ) of the lateral ventricles and the subgranular zone (SGZ) of the dentate gyrus (DG) in the hippocampus. Neurogenesis in DG is regulated both by physiological and pathological activities at all stages. Furthermore, each of these processes is subject to regulation by numerous intrinsic and extrinsic factors. Hippocampus is a crucial structure for the formation of certain types of memory. Genetic and environmental factors that affect adult hippocampal neurogenesis also cause corresponding changes in cognitive performance, suggesting the putative function of adult hippocampal neurogenesis in learning and memory. Pathological conditions such as epilepsy and prenatal treatment of an anti epileptic drug (valproic acid; VPA) cause misregulation of adult neural stem cell populations in the adult hippocampus in mice, and the resulting abnormal neurogenesis leads to impairment in learning and memory. We found that microglia in the mouse hippocampus attenuate convulsive seizure-mediated aberrant neurogenesis through the activation of Toll-like receptor 9 (TLR9), an innate immune sensor known to recognize microbial DNA and trigger inflammatory responses. We also found that impairments from prenatal VPA treatment could be ameliorated by voluntary running. These findings thus suggest the existence of bidirectional communication between the innate immune and nervous systems for the maintenance of adult brain integrity and that detrimental effects that persist until adulthood may be offset by a simple physical activity.

Keywords: adult neurogenesis, hippocampus, TLR9, valproic acid, voluntary

running.

xv The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Invited Speaker 1 – Profile

Dr. Berry Juliandi is Lecturer in Department of Biology, Bogor Agricultural University (IPB). He currently heads the Laboratory for Veterinary Stem Cells at the Centre for Natural Resources & Biotechnology Research (PPSH-IPB). He is also the chief editor of HAYATI Journal of Biosciences (indexed by Scopus).

His research interests include epigenetic regulation of neural stem cell differentiation, neurogenesis and memory, morphometrics and human biology. Berry obtained his doctoral degree in molecular neuroscience from Nara Institute of Science & Technology, Japan.

Across the span of his career, Berry has received several national and international awards. He was selected to become member of Indonesian Young Academy of Sciences (ALMI) in 2016.

xvi The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Invited Speaker 2

FEED AND FOOD SAFETY ALTERNATIVES’ FEED ADDITIVES TO ANTIBIOTICS AS GROWTH PROMOTERS IN

ANIMAL PRODUCTION

Samadi1*

1Animal Husbandry Department, Agricultural Faculty, Syiah Kuala University,

Darussalam Banda Aceh, Indonesia, 23111


Abstract

Animal feed has a very important role in the worldwide food industry and is

main component for sustainable animal production. With increase of population

and income, consumption of animal products as protein sources is also

improved. Feed which is an integral part of food chain has responsible for

human health. Antibiotics have been administrated as growth promoters in sub-

therapeutic dose to improve animal production performance for several

decades. However, due to adverse effects of antibiotics as animal feed such as

resistant bacteria and to ensure the safety of animal products, antibiotics have

been banned as feed additives in animal production. European Union according

to European Parliament and Council Regulation EC No. 1831/2003 has

prohibited in applying antibiotics as growth promoters since 2016 and

Indonesia has been forbidden to use antibiotics in animal feed since January

2018. Due to the ban of antibiotics as growth promoters, other

alternatives/replacement feed additives have been proposed to produce the

safety of animal-derived food. There are several alternatives feed additives as

replacement of antibiotics applied in feed such as pro- pre-, and synbiotics,

phytogenic (plant extract), organic acids, immunomodulatory, enzyme and so

on. These alternatives of feed additives can replace the role of antibiotics as

animals’ feed additives in animal production. The results of some studies

indicated that administration of aforementioned feed additives was able to

reduce the rate of mortality, enhance animal growth and feed efficiency, and

improve the quality of animal products. This paper aims to review the role of

alternatives’ feed additives to antibiotics as growth promoters in animal

production. The sources of this review were from some published articles in

various reputed journals.

Keywords: antibiotics, growth promoters, herbal, immunomodulatory and pre-

probiotics.

xvii The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Invited Speaker 2 – Profile

Prof. Samadi graduated from Syiah Kuala University and continued his study for master’s degree at Melbourne Australia. In 2000, he was awarded DAAD scholarship to continue PhD program at Goettingen University and finished in 2006 with the focused-on Animal Nutrition.

There are some research collaborations that have been conducted with others University such as Saskatchewan University in Canada and also with Goettingen University.

Right now, He is also coordinator at Syiah Kuala University with Erasmus+ program such as Experts Program, INDOPED dan SPIRE. These programs involve several countries both Europe and Asian. He is also reviewer in some International and National Jurnals and has a role as chief editor of Agripet Journal at Animal Science Department at Unsyiah as well as the Dean of Agricultural Faculty, Syiah Kuala University.

xviii The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Guidelines

Official Language

The official language for the 8th AIC on Health and Life Sciences 2018 is English. All presentation including Question and Answer (Q&A) must be delivered in English.

Guideline for Participant

o Conference Venue Opening, Keynote Session, Gala Dinner, and Closing Ceremony

Academic Activity Center (AAC) Auditorium Prof. Dr. Dayan Dawood, Syiah Kuala University, Jalan Teuku Nyak Arief, Kota Pelajar Mahasiswa (Kopelma), Darussalam, Banda Aceh, 23111 Indonesia

Parallel Sessions Flamboyan B-303, 3rd Floor, Academic Activity Center (AAC) Flamboyan B-306, 3rd Floor, Academic Activity Center (AAC)

o Registration Time for registration: 08:00AM – 08:30AM, Wednesday, September 12th, 2018 at Academic Activity Center (AAC) Auditorium.

o Conference Kits Conference kit, which contains Conference Book of Program, Final Program Schedule, Electronic Proceedings in CD-ROM, Participant Badge, Seminar Kits, and Official Receipt is provided to participants during check-in at Registration/Information Help Desk on Wednesday, September 12th, 2018.

o Certificate The certificates are provided to the presenters and participants after the parallel sessions.

Guideline for Presenters and Session Chairs (Moderator)

o The presenters and sessions chairs are asked to keep to the paper sequence as shown in the Final Program Schedule. By following the predefined schedule, participants can switch between sessions without missing the particular paper of interest.

o All session chairs are requested to attend to the session’s room 10 minutes before the session begins.

o All presenters are requested to report their attendance to the session chair 10 minutes before the session starts.

o The presentation is conducted as panel and divided into two sections in a session. Each section will take for 40 minutes that comprised of 3-4 presenters and continued with Q&A for 10-15 minutes. The session chairs should allow each of presenter for a 10 minutes’ presentation and leave the remaining minutes for discussion.

o Notebook/Desktop PC and LCD projectors are available in every session room.

o Presenters are recommended to prepare their files in Microsoft Power Point format on a USB flash drive and copy in the PC at session room before the session begins. Our volunteers shall assist the presenters to copy the files before presentation.

xix The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Maps and Location

Legend: Academic Activity Center (AAC) Auditorium Prof. Dr. Dayan Dawood, Syiah Kuala University

xx The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

AAC Auditorium Venue Map

xxi The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Parallel Sessions Venue Map

xxii The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Technical Program Schedule

Day1: Wednesday, September 12, 2018

Time Description Venue

07:30 - 08:00 Registration AAC Main Gate and Flamboyan 2nd and 3rd floor

08:00 - 09:15 Parallel Session I Flamboyan 2nd and 3rd floor

09:20 - 09:40 Opening by MC & Prayers (Reciting Qur’an, Seulawat Badar, Pray)

Academic Activity Center (AAC) Prof. Dayan Dawood Auditorium

09:40 - 09:50 Singing the National Anthem of Indonesia (Indonesia Raya)

09:50 - 10:05 Traditional Dance Performance: Rapa’i Geleng by Sanggar Seni Seulaweut

10:05 - 10:15 Welcoming Remark by the Conference Chairman

10:15 - 10:30 Welcoming Remark by the Rector of Syiah Kuala University

10:30 - 10:40 Profile of Syiah Kuala University

10:40 -10:50 Photo Session

10:50 - 11:15

Keynote Session

Keynote Speaker 1 : Prof. Dr. Ahmad Fauzi Ismail

11:15 - 11:40 Keynote Speaker 2: Dr. Konstantinos Gkatzionis

11:40 - 12.05 Keynote Speaker 3: Dr. Evan Lau

12:05 -12:25 Discussion

12:25 - 12:35 Plaquatte Handover & Photo Session

12:35 -13.45

Lunch Break

13:45 – 15:15 Parallel Sesion 2 Flamboyan 2nd and 3rd floor

15:30 -16:00 Invited

Speaker Sesion 1

Invited Speaker 2: Dr. Berry Juliandi (Bogor Agricultural Institute, Indonesia)

Flamboyan 2nd and 3rd floor

16:00 – 16:15 Break


16:15 – 17:15 Parallel Sesion 3

17:15 – 19:30 City tour of Banda Aceh and Magrib Praying in Masjid Baiturrahim Ulee Lheue

Academic Activity Center (AAC) Prof. Dayan Dawood Auditorium 19:30 – 21:45 Official Gala Dinner and Acehnese Art/Dance Performances *)

xxiii The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

*) Official Gala Dinner and Acehnese Art/Dance Performances


19:30 - 19:50 Dinner

Academic Activity Center (AAC) Prof. Dayan Dawood Auditorium

19:50 - 20:05 The Aceh Contemporary Folk Songs (by Cikal on Centre for The Arts of Unsyiah)

20:05 – 20:15 Greeting by the Rector of Syiah Kuala University

20:15 – 20:25 Greeting by the Major of Banda Aceh City*

20:40 – 20:55

The Aceh Contemporary Folk Songs (by Cikal on Centre for The Arts of Unsyiah) The Aceh Performing Art Form (by Likok Troupe on Centre for the art of Unsyiah)

20:55 – 21:45 The Aceh Contemporary Folk Songs (by Cikal on Centre for The Arts of Unsyiah)

Day 2: Thursday, September 13, 2018


08:30 – 10:00 Parallel Sesion 4

10.00 – 10.15 Coffee Break

10:15 – 10:40

Invited Speaker Sesion 1

Prof. Dr. Ir. Samadi, M.Sc. (Syiah Kuala University, Indonesia)


10:45 – 11:45 Parallel Session 5 and Poster Session Flamboyan rooms

11:45 – 12:30 Visit to Unsyiah Innovation Expo, book fair and souvenir market

AAC main building 12:30 – 13:30 Lunch Break

13:30 – 16:00 Visit to Center of Aceh Craft or Coffee Solong Aceh Traditional Coffee center

16:30 – 18:00 Closing ceremony and the announcement of best papers and best presenters

VIP Rooms

Day 3: Friday, September 14, 2018 (BANDA ACEH CITY TOUR)


08.00 – 08.30 Check in and registration for city tour AAC Dayan Dawood

08.30 – 12.00 Islamic and Tsunami City Tour in Banda Aceh City of Banda Aceh

xxiv The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Parallel Sessions

Parallel Session 1

Time : 12th September 2018, Wednesday/08:00 – 09:15/B303-A

Session Chair : dr. Tristia Rinanda, M.Si.

Paper ID Authors Titles of Paper

1338 Zufendi Zulfendi, Rinaldi

Idroes, Khairan Khairan

Isolation and identification of Fungal

Endophytes Fusarium sp from Gaharu

(Aquilaria sp) Population originated from

the Forest of Aceh Tamiang District

1133

Dian Hasni, Novia Mehra

Erfiza, Cut Nilda,

Muhammad Faiz

Sensory and Physical Quality Assessment

of Sie Reuboh (Cooked Meat- An

Acehnese Traditional Cuisine)

1614

Rita Andini, Evan

Febriansyah, Ashabul Anhar,

Muhammad Ikhsan

Sulaiman

The Role of Plant Genetic Resources in

Encountering Climate Change Challenge

1634 Rina Sriwati, Tjut Chamzurni,

Tiara Kusuma Pertiwi

Can Trichoderma Pellets Suppressing The

Development of Synchytrium

pogostemonis Disease in Patchouli Plants?

1562

Firdayani Firdayani,

Churiyah Churiyah, Billy

Witanto

Preparation of 3-Carbamoyl Emodin and

Its Cytotoxic Effect Against Hepg2 Cell

Line

xxv The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Parallel Session 1

Time : 12th September 2018, Wednesday/08:00 – 09:15/B303-B

Session Chair : Dr. Ir. Jauharlina, M. Sc.


1701

Cut Husna, Teuku Tahlil,

Hajjul Kamil, Mustanir

Mustanir, Rizka

Hayaturrahmi

Nurses’ Preparedness in Emergency

Management System on Disaster

1160 Khairan Khairan, Soraya

Septiya, Murniana Murniana

Antibacterial Activity of Magnolia alba

Flowers Extracts on Staphylococcus

epidermidis and Staphylococcus aureus

1695 Teuku Husni T. R. Prevent and Treat Epistaxis with

Bioflavanoids

1280

Muhammad Ikhsan

Sulaiman, Irman Syahroni,

Rita Andini, Lukman Hakim

Quality of Wheat Genotype Dewata

Growth under Wet Tropical Climate of

Indonesia

1332

Cut Nila Thasmi, Tongku

Nizwan Siregar, Sri Wahyuni,

Dwinna Aliza, Hamdan

Hamdan, Budianto

Panjaitan, Nuzul Asmilia,

Husnurrijal Husnurrijal

Steroid Level of Repeat Breeding Aceh

Cattle Synchronized with PGF2α

xxvi The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Parallel Session 2

Time : 12th September 2018, Wednesday/13:45 – 15:15/B306

Session Chair : drh. Teuku Reza Ferasyi, MSc., PhD


1500

Nuzul Asmilia, Yudha

Fahriamal, Mahdi Abrar,

Rinidar Rinidar

Toxicity Sub-cronic Ethanolic Extract of

Malaka (Phyllanthus emblica) Leaves on

Liver Function of Mice (Mus musculus) be

Reviewed from Serum Bilirubin Level

1405

Murna Muzaifa, Dian Hasni,

Dewi Yunita, Febriani

Febriani, Anshar Patria,

Amhar Abubakar

Amino Acid and Sensory Profile of Kopi

Luwak (Civet Coffee)

1863

Muhammad Sayuthi,

Hasnah Hasnah, Alfian

Rusdy, Susanna Susanna,

Auliani Auliani

Diversity of Arthropods at the Arabica

Coffee Plantation in Atang Jungket

Village, Aceh Tengah Regency

1671

Hartati Oktarina, Lidija Siller,

James Woodhall, Ian

Singleton

The Potential of Silver Nanoparticles To

Control Rhizoctonia solani (AG3-PT)

Growth In Vitro

1929 Aman Yaman

Utilization of Local Fish Meal Waste as A

Substitute Protein Source To Reduce the

Cost of Broiler Diet

1553

Zinatul Hayati, Syamsul Rizal,

Masralena Siregar, Wilda

Mahdani, Teuku Fadrial

Karmil, Ridhia Putri

Outcome Carbapenem-Resistant

Enterobacteriaceae (Cre) Clinical

Speciment Isolate In Zainoel Abidin

General Hospital Banda Aceh Year 2017

xxvii The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Parallel Session 3

Time : 12th September 2018, Wednesday/16:15 – 17:15/B306

Session Chair : Dr. Suhartono, M.Sc.


1538

Syaukani Syaukani, Graham

J Thompson, Seiki Yamane,

Ahmad Sofiman Othman,

Samingan Samingan, Djufri

Djufri, Muhammad Ali,

Hasanuddin Hasanuddin,

Husni Husni

Taxonomy of the Genus Longipeditermes

Holmgren (Termitidae: Nasutitermitinae)

from the Sunda Region, Southeast Asia

1294

Muhammad Hambal, Rizka

Ayuni, Henni Vanda,

Mustafa Sabri, Farida Farida

Sex and Body Condition are Correlated to

Prevalence and Parasitic Intensity of

Trematode Infection in Aceh Cattle

1544 Miftahuddin Miftahuddin,

Inas Salsabila

Comparison of Cox Models in Detecting

Factors Affecting Healing Rate of Dengue

Hemorrhagic Fever

xxviii The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Parallel Session 4

Time : 13rd September 2018, Thursday/08:30 – 10:00/B303-A

Session Chair : Ns. Suryane Sulistiana Susanti, S.Kep., M.A, Ph.D.


1719

Safrida Safrida, Devi

Syafrianti, Miftahul Jannah,

Musri Musman, Muhammad

Iwan Kurniawan

Utilizion of Ethanolic Eucalyptus urophylla

Leaf Extract For Mortality And Behaviour

Larvae of Culex quinquefasciatus As

Bioinsecticide

1235

Fithria Fithria, Teuku Tahlil,

Adlim Adlim, Syarifah

Rauzatul Jannah,

Darmawati Darmawati, Cut

Dirna Armada

Psychological Well-Being Among Smokers’

Adolescence

1469

Rahmi Agustina, M. Ali

Sarong, Fredinan Yulianda,

Suhendrayatna

Suhendrayatna, Rahmadi

Rahmadi

Density, Growth Pattern, and Dispersion

Pattern of Faunus ater at Reuleng River

Leupung Aceh Besar

1222

Darmawati Darmawati,

Teuku Tahlil, Toungku Nizwan

Siregar, Hajjul Kamil, Fithria

Fithria, Masyithah Audina

Antenatal Care and Iron Deficiency

Anemia

1231

Yusya' Abubakar, Dian

Hasni, Murna Muzaifa, Heru

Prono Widayat, Sulaiman

Sulaiman, Mahdi Mahdi

Impacts of Coffee Varieties and

Processing Practices on The Physical and

Sensory Characteristic of Gayo Arabica

Specialty Coffee

1597

Muhammad Nasir, Farah

Aulia Putri, Raudhatul Ulfa,

Mardianti Mardianti, Firdus

Firdus, Munira Munira, Zainal

Abidin Muchlisin, Saiful

Saiful, Suhendrayatna

Suhendrayatna

Diversity and Distribution of Fresh Water

Fishes In Krueng Sabee River, Aceh Jaya,

Indonesia

xxix The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Parallel Session 4

Time : 13rd September 2018, Thursday/08:30 – 10:00/B303-B

Session Chair : Ir. Sugianto, M.Sc, PhD


1413

Suryawati Suryawati, Putri

Indini, Zulfitri Zulfitri, Vera

Dewi Mulia

A preliminary study: Antihyperglicemic

activities of Phaleria macrocarpa (Sheff)

Boerl.) and Sitagliptin, an inhibitor of

dipeptidyl peptidase IV (DPP-IV)

1603

Gholib Gholib, Muhammad

Agil, Iman Supriatna,

Bambang Purwantara, Triva

Murtina Lubis, Mulyadi

Adam, Azhar Azhar

Non-Invasive Monitoring of Stress in

Females Crested Macaques (Macaca

nigra): Comparison of Glucocorticoid

Levels during Cycling, Pregnancy and

Lactation

1693 Aria Gusti, Tria Ananda Subjective Work Fatigue and Related

Factors on Silungkang Weavers

1552 Wilda Mahdani

The Profile of Bacterial Urinary Tract

Infection Aetiology Isolated from

Hospitalized Patients in dr. Zainoel Abidin

General Hospital Banda Aceh

1211

Mailisa Mailisa, Cut Meliana,

Cut Maysura Hanum, Yanti

Meldasari Lubis, Novia

Mehra Erfiza, Heru Prono

Widayat

Potency Antioxidant Compounds of

Indian Gooseberry (PHYLLANTHUS

EMBLICA) Leaves as Herbal Tea

1511 Sukma Aditya Sitepu, Julia

Marisa

Combined Effect of Streptomycin and

Sweet Orange Essential Oil To Membrane

and Acrosome Integrity Boer Goat Frozen

Semen

xxx The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Parallel Session 5

Time : 13rd September 2018, Thursday/10:45 – 11:45/B303-A

Session Chair : Prof. Dr. Ir. Samadi, M.Sc.


1152 Eva Berthy Tallutondok

Childhood Activities Memories Amongst

Healthy Adults in The Model of

Intervention Reminiscence Based

Screening

1414

CHANATHIP THAMMAKARN,

Pham Hoang Son Hung,

Sirichai Eardmusic

Porcine Reproductive and Respiratory

Syndrome Virus, Porcine Circovirus and

Pasteurella multocida Co-Infection in Pigs

1549 Normalina Arpi, Fahrizal

Fahrizal, Syarifah Rohaya

Physical Properties of Composite

Biodegradable Films Based on Tuna-Skin

Gelatin and Chitosan

1521 Julia Marisa, Sukma Aditya

Sitepu

Analysis Relationship between Production

Factors with Business Production of Broiler

Chicken in Beringin Village Deli Serdang

Regency

xxxi The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Parallel Session 5

Time : 13rd September 2018, Thursday/10:45 – 11:45/B303-B

Session Chair : Darwin, S.TP., M.Sc., Ph.D.


1411

Sarah Firdausa, Maung

Maung Cho, Khin Maung

Maung, Nilar Aung,

Norsidah Kuzaifah

The Effect of Tinospora crispa on Anti

Oxidant Status in Streptozotocin Induced

Diabetic Rats

1210

Doti Wahyuningsih, Annisa

Amilia, Asri Cahyaningrum,

Laili Cinthianur Kurniasari,

Meilano Setiawan

Amiruddin

Pomegranate Peel Potency as a

Preventive Agent of Rheumatoid Arthritis

1281 Nabiila Kaltsum Ulayya, Udi

Tarwotjo, Rully Rahadian

Lime Leaves Ethanol-Extract, Cajuput Oil,

and its Combination Effects To Rice Weevil

Mortality

1545 Rizqa Rahmati, Anwar

Anwar, Anizar Ahmad

Remedial Learning Based Scaffolding for

Students Increase Low

xxxii The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

Poster Session

Time : 13rd September 2018, Thursday/10:45 – 11:45/AAC Main

Building

Session Chair : Dr. Suhartono, S.Si, M.Sc.


1418 Rita Hayati, Efendi Efendi,

Fitri Yunita

Sensory Evaluation With Descriptive

Method On Aceh Local Rice (Oryza

Sativa L.) Mutant M6 Using Gamma-

Ray Irradiation

1999

Sukma Rizki Ariga, Yuliani

Aisyah, Anshar Patria,

Normalina Arpi, Dewi

Yunita

Physicochemical Characterization of

Oil From Roasted Coffee

2079

Martina Fitri Wahyuni,

Dewi Yunita, Yusriana

Yusriana, Yuliani Aisyah

Chemical and Microbiological

Characteristics of Cocoa Beans From

Pidie District, Aceh Province, Indonesia

2080 Novi Mailidarni, Anshar

Patria, Yuliani Aisyah

Treatment of Introduction of Leaf

Fermentation and Distilation on

Eucalyptus Oil Rendemen

2083 Yuliani Aisyah, Sri Haryani,

Ayu Simah Bengi

Effects of Type and Concentration

Stabilizers on The Characteristics of

Nutmeg Oil Nanoemulsions Prepared

by High Pressure Homogenization

1568

Erlidawati Erlidawati,

Musri Musman, Safrida

Safrida

Antihyperglycemic Potential of

Helminthostachys zeylanica Leaves

Extract in Diabetic Rats

ABSTRACTS

The 8th AIC on Health and Life Sciences

The Annual International Conference 2018 Syiah Kuala University

“Connecting the World through Innovation and Sustainable Development”

Banda Aceh, Aceh, Indonesia September 12-14, 2018

1 The 8th AIC on Health and Life Sciences 2018 – Syiah Kuala University

THE POTENTIAL OF SILVER NANOPARTICLES TO CONTROL

Rhizoctonia solani (AG3-PT) GROWTH IN VITRO

Hartati Oktarina1*, Lidija Siller2, James Woodhall3, and Ian Singleton4

1Department of Plant Protection, Syiah Kuala University, Darussalam-Banda Aceh

23111, Indonesia 2Chemical Engineering and Advance Material, School of Engineering, Newcastle

University, UK. 3Parma Research and Extension Center, Department of Entomology, Plant Pathology

and Nematology, University of Idaho, USA. 4Environmental Microbiology, School of Applied Science, Edinburgh Napier

University, UK.


ABSTRACT

Silver nanoparticles (AgNPs) have known anti-microbial properties and therefore have

the potential to be used to control fungal plant pathogens. In this study we investigated

the growth of a plant pathogenic fungus, Rhizoctonia solani (AG3-PT) in the presence of

AgNPs. The effect of AgNPs at two different levels (20 and 50 mg L-1) was investigated

on the hyphal growth and also the sclerotia of R. solani. The results showed that at 20

mg AgNPs L-1 R. solani hyphal growth was reduced along with the production of

sclerotia. The results indicate that AgNPs have the potential to control R. solani growth

and subsequent development of plant disease symptoms.

Keywords: fungi, plant pathogen, sclerotia.


NURSES’ PREPAREDNESS IN EMERGENCY MANAGEMENT SYSTEM ON

DISASTER

Cut Husna1*, Teuku Tahlil2, Hajjul Kamil3, Mustanir4, Rizka Hayaturrahmi5

1Medical and Surgical Nursing Department, Faculty of Nursing Syiah Kuala

University Darussalam-Banda Aceh/Doctoral Student of Mathematic and

Applied Science

Syiah Kuala University Darussalam-Banda Aceh 23111, Indonesia 2Community Nursing Department, Faculty of Nursing Syiah Kuala University

Darussalam-Banda Aceh 23111, Indonesia 3Management of Nursing Department, Faculty of Nursing Syiah Kuala University

Darussalam-Banda Aceh 23111, Indonesia 4Professor at Chemistry Department, Faculty of Science Syiah Kuala University

Darussalam-Banda Aceh 23111, Indonesia 5Nursing Student Faculty of Nursing Syiah Kuala University

Darussalam-Banda Aceh 23111, Indonesia


ABSTRACT

Nurses are leading professionals as providers of care in emergency or disasters.

The health care system in the emergency response situation will succeed in preventing

and reducing the mortality rate of the victims by implementing emergency response

system at the health care facilities. The study aims to identify nurses’ preparedness in

emergency response systems on disaster management at Maternal and Child Hospital

Banda Aceh. The variables of research are disaster response system, communication

network, and ambulance transportation system. The research of study is descriptive

quantitative with cross sectional study design. The sample of the study was total sampling

of 103 nurses in Maternal and Child Hospital Banda Aceh. Data was collected by

questionnaires in dichotomous scale consisted of 33 questions developed by the

researcher. The questionnaires consisted of disaster emergency response system,

communications network, the ambulance transport system tested validity and reliability

with scored 0.611, 0.698, 0.621, and 0.962 respectively. The results of the study showed

that nurses’ preparedness in emergency respond system in disaster management was well

prepared (73.8%). The variables of the study showed that for disaster emergency

response system (53.4%) was unprepared. Moreover, for communications network

(64.1%) and the ambulance transport system (77.7%) of respondents were well prepared

respectively. Nurses preparedness in emergency response system on disaster

management in the hospital was well prepared, particularly on communications network

and the ambulance transport system. It recommended to the hospital effectively conduct

to disaster management, disaster simulation exercises, and develop standard operating

procedures related of disaster management systems.

Keywords: disaster, emergency, hospital, nurse, preparedness.

mailto:[email protected]


UTILIZION OF ETHANOLIC Eucalyptus urophylla LEAF EXTRACT FOR

MORTALITY AND BEHAVIOUR LARVAE OF Culex quinquefasciatus AS

BIOINSECTICIDE

Safrida Safrida1*, Devi Syafrianti1, Miftahul Jannah1, Musri Musman2,

Muhammad Iwan Kurniawan1

1 Department of Biology Education, Faculty of Teacher Training and Education

Syiah Kuala University, Darussalam, Banda Aceh, 2311, Aceh, Indonesia 2Department of Chemistry Education, Faculty of Teacher Training and Education

Syiah Kuala University, Darussalam, Banda Aceh, 2311, Aceh, Indonesia

* Corresponding author e-mail: [email protected]

ABSTRACT

Mosquito is a vector of infectious diseases with the most extensive distribution in the

world. One of the most successful genus to breed is Culex sp. Culex sp. is a vector of

filariasis disease was causing efects in humans. One of effective way to break the chain

of mosquito development that their eggs oviposit in waters ranging from waste water

areas to bird baths, old tires, or any container that holds water and require between five

to eight days. The larvae progress through four larval instars, and towards the end of the

fourth instar they stop eating and molt to the pupal stage is using larvacides. Eco-friendly

larvacides can be used to control and disease prevention that caused by Culex sp. One of

alternative natural larvacide is using eucalyptus leaf extract (Eucalyptus urophylla)

caused by exposure of bioactive compounds contained in eucalyptus leaf extract in the

form of essential oils, saponin, and tannin. This study used to determine the effect of

ethanol leaf extract of eucalyptus as larvicidal towards mortality and behavior (mobility

and position) of Culex quinquefasciatus larvae. This study used an experimental method

with Completely Randomized Design, consisting of 6 treatments and 4 replications. The

treatments that used were K- (well water), P1 (concentration of 1000 ppm eucalyptus leaf

extract), P2 (concentration of 2000 ppm eucalyptus leaf extract), P3 (concentration 3000 ppm eucalyptus leaf extract), P4 (concentration 4000 ppm eucalyptus leaf extract), and

K+ (thermephos). The object of this research has 600 larvae of Culex quinquefasciatus

obtained from Parasitology Laboratory, Faculty of Veterinary Medicine, Syiah Kuala

University. The data of the research were analyzed using Analysis Of Variant (ANOVA)

and Probit Regression Analysis. The results showed that eucalyptus leaf extract infuence

significantly (P<0.05) on mortality and behavior of Culex quinquefasciatus larvae. The

concentration of extract caused 50% of Culex quinquefasciatus larvae dead (LC50) was

1093,75 ppm, concentration of 4000 ppm eucalyptus extract can significantly affect

larval mobility and for the position of the larvae at first hour of observation was attaching

to the bottle then slowly down to the bottom of the bottle and showed no further

movement. Based on the results of this study it can be concluded that the number of

mortality Culex quinquefasciatus larvae and changed behavior (mobility and position)

of Culex quinquefasciatus larvae is caused by eucalyptus leaf extract.



Keywords: Culex quinquefasciatus, Eucalyptus urophylla , Mortality,larvicide, and

filariasis.

SENSORY AND PHYSICAL QUALITY ASSESSMENT OF SIE REUBOH

(COOKED MEAT- AN ACEHNESE TRADITIONAL CUISINE)

Dian Hasni1*, Novia Mehra Erfiza1, Cut Nilda1 and Muhammad Faiz1

1Agricultural Product Technology Department, Agriculture Faculty, Syiah Kuala

University, Darussalam - Banda Aceh 23111, Indonesia


ABSTRACT

Sie reuboh is an Acehnese traditional cuisine which used red-meat as main protein, then

is prepared specifically with the addition of beef tallow, traditional vinegar and complex

of spices as major spices ingredients. The dish is extremely popular and originally came

from Great Aceh districts. It has long shelf life, exquisite and complex taste. However

due to the changing life styles and modernization of society, the dish becoming rare and

only cooked during the fest days. Later on the recipes and formulation are also varied

over the cities. With the help of previous studies, the updated formulation is defined,

where added proportion of beef tallow (0%, 25%, 50%) and vinegar (2.5% and 5%) are

used as independent variables. Continuing it, then this study aims to assess the physical

quality (pH and cooking loss) and sensory quality of four main attributes: color, aroma,

flavor, texture based on that above factors. The sensory attributes then later divided onto

ten specific attributes, which is assessed with Qualitative Descriptive Analysis (QDA)

method. The laboratory experiments used Factorial Randomized Block Designs three

repetitions, then it continued with Duncan's Multiple Range Test (DMRT). The analysis

of variance (ANOVA) showed that addition of beef tallow is significantly influenced

(P≤0.01) the umami flavor of sie reuboh, whereas the addition of vinegar significantly

(P≤0.01) influenced the pH, cooking loss, color, meat flavor, sour flavor, tenderness and

chewiness of produced sie reuboh descriptively. The sensory profile of each treatments

are also specifically described, where the increasing amount of vinegar tends to decrease

the pH, prevents the cooking loss and elevates the colour, tenderness and sour flavor of

the product. Later the correlation within these descriptive attributes within the consumer

acceptance of sie reuboh is also presented, where the consumer acceptance of this

traditional product tends to correlate with the colour, the sour flavor and tenderness of

the product.

Keywords: Acehnese traditional cuisine, meat-flavor, red-meat, sie reuboh, QDA.


EVALUATION OF ANTIOXIDANT, ANTIBACTERIAL POTENTIAL,

NUTRITION VALUE AND ACUTE TOXICITY STUDY OF LIBYAN DATE

PALM POLLEN (DPP)

Ramin Basher Ashour1, Abdulrzag A. Auzi1, Rabya A. Lahmer2*

1Department of Pharmacognosy, Faculty of Pharmacy, University of Tripoli, Tripoli,

Libya 2Department of Food Science and Technology, Faculty of Agriculture, University of

Tripoli, Tripoli, Libya


ABSTRACT

The pollen of date palm -DPP (Phoenix dactylifera L) is belonging to Arecaceae family,

have a wide distribution in many areas including the Middle East and North Africa.

Phoenix dactylifera L has nutritional, medicinal, economic and ecological benefits for

the treatment of various health diseases and disorders such as antimicrobial, anti-

oxidative, anti-inflammatory, anti-toxicant, anti-cancer, enhancer of fertility in both

males and females and hepato-protective activities. The aim of this research was to assess

the phytochemical screening, antioxidant activity, antibacterial effect and acute toxicity

test of the Phoenix dactylifera L cultivated in Libya. The antioxidant activities of the

extracts were screened using DPPH assay, the results indicated that the Palm pollen grain

water- extract showed the best DPPH scavenging activity (IC5o = 0.0005) while DPPH

scavenging activity being recorded for palm pollen grain methanol extract at 70c°(

IC5o=0.233 mg/ml) and palm pollen grain methanol extract at 45c°(IC5o= 0.224mg/ml).

The methanol extracts of palm pollen grain (at conc12.5mg/ml, 25mg/ml, 50 mg/ml and

100mg/ml) were tested against 5 different strains of standard bacteria (ATCC) by cup cut

method, the result showed no remarkable inhibition of bacterial growth. The

phytochemical screening of date palm pollen revealed the presence phytosterols,

flavonoids, coumarins, tannins, phenolic compounds and amino acids and protein and

the present small amount of saponin, and fats. The proximate nutritional value of palm

pollen grains were analyzed. The results obtained showed that the values of moisture

(18.19%), ash (5.41%), crude fiber (67%), crude fat (7.32%), Crude protein (27.36%).

Acute toxicity test of methanol extract showed no mortality amongst the graded dose

groups of animals or any behavioral changes at the highest dose of 5,000 mg/kg.

Keywords: date palm, phytochemical screening, antioxidant activity, antibacterial

effect, acute toxicity test.



QUALITY OF WHEAT GENOTYPE DEWATA GROWTH UNDER WET

TROPICAL CLIMATE OF INDONESIA

M I Sulaiman1*, I Syahroni1, R Andini2 and L Hakim3

1 Department of Agricultural Products Technology, Syiah Kuala University,

Darussalam-Banda Aceh 23111, Indonesia 2 Department of Forestry, Syiah Kuala University, Darussalam-Banda Aceh 23111,

Indonesia 3 Department of Plant Protection, Syiah Kuala University, Darussalam-Banda Aceh

23111, Indonesia


ABSTRACT

Along with prosperity improvement of countries in the tropic, the consumption

of wheat-based products such as breads, cakes, noodles and cookies has increasing

tendency in the recent years. Wheat that is grown usually in the sub-tropic has been

investigated intensively for cultivation trial in tropical region. Successful cultivation of

wheat in the tropic has been reported but the information on its quality was still very few.

This paper reported the quality of wheat grown in the field at 5 different provinces of

Indonesia at an altitude varied from 1000 up to 1650 meter above sea level. Two samples

of wheat from each location were taken and analyzed the physical, chemical, pasting and

dough properties. The quality of Dewata genotype of wheat was varied depending on the

planting location. Out of five planting location, only Jawa Tengah could produce quality

wheat. Meanwhile the wheat from other locations characterized by weak in pasting and

dough properties. Wheat with weak pasting and dough properties could not be used for

bread and noodle production, however they still can be used to produce cookies and cake.

There was an indication of starch or gluten damage probably caused by high enzymatic

activity of fungi infestations. In the wet tropical climate of Indonesia, fungi could easily

develop at any kind of agricultural products. In the future, agriculture practice in

Indonesia should be improved in order to produce better quality of wheat.

Keywords: Dewata genotype, dough, paste, quality, wet tropic, wheat.



TOXICITY SUB-CRONIC ETHANOLIC EXTRACT OF MALAKA

(Phyllanthus emblica) LEAVES ON LIVER FUNCTION OF MICE

(Musmusculus) BE REVIEWED FROM SERUM BILIRUBIN LEVEL

Nuzul Asmilia1,2, Yudha Fahrimal3, Mahdi Abrar4, Rinidar5

1Study Program DMAS, Syiah Kuala University, Banda Aceh 23111, Indonesia 2 Clinical Laboratory of Veterinary Medicine, Syiah Kuala University, Banda Aceh

23111, Indonesia 3Parasitology Laboratory of Veterinary Medicine, Syiah Kuala University, Banda Aceh

23111, Indonesia 4 Microbiology Laboratory of Veterinary Medicine, Syiah Kuala University, Banda

Aceh 23111, Indonesia 5Farmacology Laboratory of Veterinary Medicine, Syiah Kuala University, Banda Aceh

23111, Indonesia

*Corresponding author E-mail: [email protected]

ABSTRACT

The aim of this research was to investigate the subchronic toxicity of ethanolic extract of

malaka leaves (Phyllanthus emblica) on liver function by analyzing bilirubin level in

mice blood (Mus musculus). Sixteen male mice weighing between 25-30 grams were

used in this study. Ethanolic extract of malaka leaves was given orally once a day for 21

consecutive days. Mice were randomly divided into 4 groups of 4 mice each. Control

group (P0) was given distilled water; group P1, P2, and P3 were administered with

ethanolic extract of malaka leaves with the dose of 300 mg/kg bb, 600 mg/kg bb, and

1200 mg/kg bb, respectively. Blood sample was taken on day 21 after treatment to

measure mice bilirubin level. The results showed that blood bilirubin level of mice in P0,

P1, P2, and P3 were 1.4; 1.4; 1.4, and 1.4mg/dl respectively. In conclusion, the

administration of ethanolic extract of malaka leaves with repeated doses for 21 days does

not have negative effect on mice liver.

Keywords: ethanolic extract of malaka leaves, liver function, bilirubin direct.



AMINO ACID AND SENSORY PROFILE OF KOPI LUWAK (CIVET COFFEE)

Murna Muzaifa1,2*, Dian Hasni2, Dewi Yunita2, Febriani3, Anshar Patria2

, Amhar

Abubakar4

1Doctoral Study Program of Agricultural Science, Syiah Kuala University, Darussalam,

Banda Aceh, 23111, Indonesia 2Department of Agricultural Product Technology, Faculty of Agriculture, Syiah Kuala

University, Darussalam, Banda Aceh, 23111, Indonesia

3Department of Chemistry, Faculty of Mathematics and Natural Science, Syiah Kuala

University, Darussalam, Banda Aceh, 23111, Indonesia 4Department of Animal Husbandry, Faculty of Agriculture, Syiah Kuala University,

Darussalam, Banda Aceh, 23111, Indonesia


ABSTRACT

Kopi luwak (civet coffee) is one of the most popular coffee in the world. This coffee

produced exclusively by Indonesian palm civet or luwak (Paradoxurus hermaphroditus)

and relatively has a high price. Many reports mentioned that compounds in coffee that

are often interfere the coffee flavor where one of them is amino acid. The aim of this

research were to identify amino acids compositions of kopi luwak (green and roasted

bean) and its correlation to sensory profile of kopi luwak. Sampel of kopi luwak collected

from six locations in Gayo Higland, Aceh-Indonesia. Amino acids composition were

analyze by LC-MS and the sensory profile were performed using cupping test based on

SCAA procedures. The result showed that green and roasted bean of kopi luwak had

significantly differences for the value compounds of L-alanine, L-Tyrosine, Cysteine and

L-Arginine. Certain amino acid contributes to develop the sensory quality of kopi luwak.

Valine, L-Glutamine, Aspartic acid and Glutamic acids are considered as the main amino

acids which have higher percentage for both green and roasted bean of kopi luwak.

Several amino acids are absence in green bean which later on enable to track its presence

in roasted bean or vice versa. Glutamic acids presents to have highest contents amongst

others, both in green bean and roasted bean. Sensory profile of civet coffee showed that

all samples classified as specialty coffee because obtained total score of cupping

(fragrance, flavor, aftertaste, body, acidity, balance, uniformity, clean cup, sweetness and

overall) above 80. Later PLS correlation showed that L-Valines, Aspartic acid, Glutamic

acid and Histidin which belong to different group have positive correlation towards

acidity, body, flavor, fragrance and overall with different R2 value.

Keywords: amino acids, cupping test, gayo highland, civet coffee.


PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS,

PORCINE CIRCOVIRUS AND Pasteurella multocida CO-INFECTION IN

PIGS

Chanathip Thammakarn1*, Pham Hoang Son Hung2 and Sirichai Eardmusic3

1Laboratory of Molecular Genetics and Cellular Biotechnology, Department of Animal

Production Technology and Fisheries, Faculty of Agricultural Technology, King

Mongkut’s Institute of Technology Ladkrabang, Bangkok 10520, Thailand 2Faculty of Animal Science and Veterinary medicine, Hue University of Agriculture

and

Forestry- Hue University, Thua Thien Hue 0234, Vietnam 3Faculty of Animal Science and Agricultural Technology, Silpakorn University,

Phetchaburi 76120, Thailand


ABSTRACT

This report aims to illustrate co-infection of important pathogens in pigs and affected to

herd health status of a farm located at Rachaburi province of Thailand. The pigs showed

unsatisfied growth performance as well as ununiform size appearance. The farm has

capacity about 700 sows with 8,000 fattening pigs. Vaccination program including

vaccines against Porcine Epidemic Diarrhea (PED) and Foot and Mouth Disease (FMD)

for sow units. While Porcine Reproductive and Respiratory Syndrome (PRRS),

Aujeszky’s Disease (AD), Porcine Circovirus type 2 (PCV2), Classical Swine Fever

(CSF), Mycoplasma and Foot and Mouth Disease (FMD) were applied for fattening pigs.

To investigate the health problem occurred with the farm, blood sampling was carried

out from accumulated ununiform pigs. Necropsy was conducted from a dead pig of the

same group for further diagnosis by polymerase chain reaction (PCR) and bacterial

culture. Serum was further test by Enzyme Linked Immunosorbent Assay (ELISA). The

obtained results from ELISA diagnosis revealed high S/P ratio of PRRS virus antibody

which can be interpreted that PRRS virus infection raised in the farm. The result from

pooled lymph node showed positive PCV2 detection by PCR. Bacterial culture from lung

sample found infected by Pasteurella multocida. Overall, it was determined that mix of

infection between viruses and bacteria occurred in this farm, PRRS, PCV2 and

Pasteurella multocida. This report is illustrated that the mutuality of infection could

breakthrough acquire immunity from vaccination, affected to health status and

production of the farm.

Keywords: Co-infection, Pasteurella multocida, PCV2, PRRS.


PHYSICAL PROPERTIES OF COMPOSITE BIODEGRADABLE FILMS

BASED ON TUNA-SKIN GELATIN AND CHITOSAN

Normalina Arpi1, Fahrizal Fahrizal1, Syarifah Rohaya1*

1Department of Agricultural Product Technology, Faculty of Agriculture, Syiah Kuala

University, Darussalam, Banda Aceh, 23111, Indonesia

*Corresponding author e-mail:

ABSTRACT

Fish gelatin as a film-forming agent is thermo-reversible and has ability to melt-in-the

mouth, but gelatin exhibit lower physical strength. Mixing gelatin with chitosan may

enhance the properties of the composite film. The purpose of this research is to

characterize biodegradable film made using tuna-skin gelatin-chitosan complex with the

addition of glycerol as plasticizer. Blending gelatin with chitosan can improve the tensile

strength of the composite film. At lower chitosan concentration, film elongation increase

as glycerol concentration increase. However, higher chitosan concentration keep the

elongation appropriate even with high glycerol concentration.

Keywords: biodegradable film, chitosan, fish gelatin, glycerol.


CAN TRICHODERMA PELLETS SUPPRESSING THE DEVELOPMENT OF

Synchytrium pogostemonis DISEASE IN PATCHOULI PLANTS?

Rina Sriwati1*, Tjut Chamzurni1, Elly Kusumawati2,Tiara Kusuma Pertiwi2

1Plant Protection Department, Faculty of Agriculture, Syiah Kuala University, Banda

Aceh 23111, Indonesia 2Agrotechnologi Department, Faculty of Agriculture, Syiah Kuala University, Banda

Aceh 23111, Indonesia


ABSTRACT

Budok disease, which is the term in Aceh for Synchytrium pogostemonis disease

infection, a disease that often attacks patchouli plants. Budok disease symptom cause

warts on leaves, stems and stalks that are swollen and thickened; reddish-purple, the

leaves look wrinkled and thick with a purplish red color. The biological control agent

that could be used for control disease pathogen were Trichoderma fungi. This fungi has

been produce as a pellet formulation and has been evaluated their potential to control

several importance pant disease. Tree week ages of Patchouli seedling were growth on 5

kg soil. Application of pellet was carried out by immersing it into the planting medium

according to the dosage tested. The doses tested were 0 g, 2.5 g, 5 g, 7.5 g and 10 g per

polybag. The transmission of S. pogostemonis sap uses a mechanical method. The

measurement of incubation period, leaf area and disease intensity was done at 120 days

after planting. The intensity of disease attacks can be calculated. The result shown that

pellet Trichoderma can suppressing the development of S. pogostemon in patchouli

plants, when the dose was raised to 10 g / polybags showing different growth symptoms,

the leaves that grow form malformations, leaf edges normally jagged to flat round, leaves

were not green as normal leaf colour.

Keywords: Budok disease, Aceh Patchouli, Pagostemon cablin Benth.


ISOLATION AND IDENTIFICATION OF ENDOPHYTIC FUNGUS Fusarium

sp FROM AGARWOOD (Aquilaria sp) POPULATION ORIGINATED FROM

THE FOREST OF ACEH TAMIANG DISTRICT, INDONESIA

Zulfendi1,2, Rinaldi Idroes3 and Khairan4*

1Graduate School of Mathematics and Applied Sciences, Syiah Kuala University,

Kopelma Darussalam, Banda Aceh 23111, Indonesia 2Human Resources Development Agency, Banda Aceh, Aceh Province

3Department of Chemistry, Faculty of Mathematics and Natural Sciences, Syiah Kuala

University, Kopelma Darussalam, Banda Aceh 23111, Indonesia 4 Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Syiah Kuala

University, Kopelma Darussalam, Banda Aceh 23111, Indonesia

* Corresponding author e-mail: [email protected]

ABSTRACT

Aquilaria sp is one of higher plant types that can produce agarwood. Agarwood is

commonly stimulated by the biological response of endophytic fungal infection of

Fusarium sp. This research aims to isolate and identify endophytic fungus

Fusariumspfrom Aquilaria sp populations originated from the forest of Aceh Tamiang

District, Indonesia. The pure isolates of Fusarium sp derived from Aquilaria sp that

reinfected on Aquilaria sp populations to stimulate agarwood formation. The endophytic

fungal isolates of Fusarium sp were growth on a selective media of Sabouraud Dextrose

Agar (SDA) containing antibiotics streptomycin 10 µg/dl and chloramphenicol 25µg/dl.

Ten percent of infected Aquilaria sp from the population then taken ten suspected

samples aseptically. Isolation and identification of endophytic fungus Fusarium sp were

conducted from June to August 2016. The results showed that 10 infected Aquilaria sp

have been found several microbes species: three species of Fusarium sp, six species of

Aspergillus sp, two species of Rhizopus sp, two species of Penicillium sp, one species

Bacillus sp, one species of Actinomyces sp and one species of Streptomyces sp. The result

of identification towards three species of endophytic fungus of Fusarium sp that has been

purified strong allegedly were Fusarium solani, Fusarium oxysporum, and Fusarium

monyliformae.

Keywords: Agarwood (Gaharu), fungal endophytes Fusarium sp, Aquilaria sp, Aceh

Tamiang District.


HETEROSIS AND HETEROBELTIOSIS OF AGRONOMIC AND YIELD

TRAITS IN THAI UPLAND RICE HYBRIDS

Wulan Kumala Sari1,2, Charassri Nualsri3, Nattapon Junsawang4 and Watcharin

Soonsuwon3*

1Tropical Agricultural Resource Management, Faculty of Natural Resources, Prince of

Songkla University, Hat Yai Campus, Songkhla 90112, Thailand 2Department of Agroecotechnology, Faculty of Agriculture, Andalas University,

Dharmasraya Campus 27573, West Sumatra, Indonesia 3Department of Plant Science, Faculty of Natural Resources, Prince of Songkla

University, Hat Yai Campus, Songkhla 90112, Thailand 4Agricultural, Resource and Environmental System Research Centre, Faculty of Natural

Resources, Prince of Songkla University, Hat Yai Campus, Songkhla 90112, Thailand


ABSTRACT

Heterosis and heterobeltiosis are used to select the best crosses for increasing the

productivity of rice. Its performance of twenty-eight F1 hybrids and their eight parents

were evaluated in a randomized complete block design with two replications at

experimental field of the Faculty of Natural Resources, Prince of Songkla University,

Hat Yai, Songkhla, Thailand during July until November 2016. Significant differences

of analysis of variance were observed among parents, hybrids, and hybrids versus parents

for most of the agronomic and yield traits. Crossed combination of Dawk Pa-yawm ×

Hawm Mali Doi had highest significant positive heterosis and heterobeltiosis for the

number of tillers (90.59%; 58.82%) and number of panicles per plant (60.35%; 46.14%),

highest significant positive heterobeltiosis for panicle length (20.05%) but had a highest

significant negative heterosis for plant height (-8.90%). Furthermore crossed

combination of Nual Hawm × Khun Nan had highest significant positive heterosis and

heterobeltiosis for yield components, such as number of filled grains per panicle

(57.39%; 52.25%), spikelet fertility (25.01%; 21.16%), highest significant positive

heterosis for panicle length (32.21%), grain weight per panicle (56.09%), 1000-grain

weight (12.85%), and grain yield per plant (19.86%) but had highest significant negative

heterosis and heterobeltiosis for days to flowering (-17.52%; -6.03%) and days to

maturity (-12.00%; -4.91%), so these were recommended as the most promising cross

combinations for developing high yielding upland rice hybrid varieties.

Keywords: heterobeltiosis, heterosis, hybrid, upland rice.


A PRELIMINARY STUDY: ANTIHYPERGLYCEMIC ACTIVITIES OF

Phaleria macrocarpa AND SITAGLIPTIN, AN INHIBITOR OF DIPEPTIDYL

PEPTIDASE (DPP-IV)

Suryawati Suryawati1*, Putri Indini 2, Zulfitri Zulfitri3, Vera Dewi Mulia4

1Department of Pharmacology, Faculty of Medicine 2School of Medicine, Faculty of Medicine Syiah Kuala University, Darussalam-Banda

Aceh 23111, Indonesia 3Department of Biology, Faculty of Medicine Syiah Kuala University, Darussalam-

Banda Aceh 23111, Indonesia 4Department of Patology Anatomy, Faculty of Medicine Syiah Kuala University,

Darussalam-Banda Aceh, 23111, Indonesia


ABSTRACT

Phenolic compounds in plants have been experimentally proven to have activity as

inhibitors of dipeptidyl peptidase IV (DPP-IV), one of enzymes responsible for the

increase in blood glucose in diabetic patients. Phaleria macrocarpa contains these

secondary metabolites in a large amount so that potentially show activity close to

sitagliptin in improving diabetes. To evaluate this activity, we conducted a study in which

ethanol extract of P. macrocarpa (EEPM) were given at dose 550 mg/kg; 1100 mg/kg;

and 1650 mg/kg in alloxan induced-diabetic rats for 7 days. The positive control was

given sitagliptin at dose 9 mg/kg while negative controls were fed aquadest. The result

revealed that the administration of EEPM and sitagliptin attenuated blood glucose level

with no significant difference (p> 0.05) which showed a promising activity of EEPM in

competing sitagliptin. This result could be a start to provide an alternative DPP-IV

inhibitor.

Keywords: Antihyperglycemic, dipeptidyl peptidase IV, Phaleria macrocarpa.


ANTENATAL CARE AND IRON DEFICIENCY ANEMIA

Darmawati1*, Teuku Tahlil2, Toungku Nizwan Siregar3, Hajjul Kamil 4, Fithria5,

and Masyithah Audina6

1Maternity Nursing Department, Faculty of Nursing, Syiah Kuala University Darussalam 23111

Banda Aceh, Indonesia/Doctoral Student of Mathematic and Applied Science Syiah Kuala

University Darussalam 23111 Banda Aceh 2Community Nursing Department, Faculty of Nursing, Syiah Kuala University Darussalam

23111 Banda Aceh, Indonesia 3Faculty of Veterinary, Syiah Kuala University Darussalam 23111 Banda Aceh, Indonesia

4Management Nursing Department, Faculty of Nursing, Syiah Kuala University Darussalam

23111 Banda Aceh, Indonesia 5Family Nursing Department, Faculty of Nursing, Syiah Kuala University Darussalam 23111

Banda Aceh, Indonesia 6Student of Nursing Faculty, Syiah Kuala University Darussalam 23111 Banda Aceh, Indonesia


ABSTRACT

Anemia in pregnancy is one of the contributor factors to the increasing of maternal

mortality rate, cause hemorrhage and sepsis during labour. Infants who born from anemic

mothers can also be premature, immune system weakness, and developmental disorders.

Globally, the most common cause of anemia during pregnancy is iron deficiency.

Indonesian Ministry of Health try to solve this problem with integrated antenatal service

program with the standards offered are middle upper arm circumference (MUAC)

measurement, weight measurement, and laboratory examination. This study aims to find

out the relationship between integrated antenatal service with iron deficiency anemia.

This study is applied using cross sectional study with non probability and purposive

sampling method. The measuring instrument was checklist and questionnaire sheets. The

sample of this study was 102 pregnant women and data analysis was done using Chi-

Square test. The relationship between MUAC and iron deficiency anemia has p-value =

0.008. MUAC is a standard in measuring nutritional status of pregnant mother that has

consistent result, so it can be used to identify the change of maternal nutritional status

including iron. The laboratory examination and iron deficiency anemia relationship has

p-value = 0.005. The blood type and hemoglobin examination is part of laboratory

examination. The blood type examination provides information about the type of blood

group that susceptible to anemia, so that it can be used to detect and prevent anemia,

while hemoglobin examination also recommended by WHO to diagnose anemia in

pregnancy. This study find out that there is no significant relationship between body

weight measurement and iron deficiency anemia (p-value = 0.808). Weight measurement

in pregnancy is not always a step to detect nutritional status in pregnancy because the

weight gain in pregnancy may also caused by other factors. This study above indicates

that anemia in pregnancy is relate with integrated antenatal care service, especially

middle upper arm circumference measurement and laboratory examination. It is

recommended to antenatal care providers to improve the quality of service that offered,

so it can make many health problems during pregnancy especially iron deficiency anemia

can be detected and handled quickly.

Keywords: anemia, antenatal, laboratory, weight.



PREVENT AND TREAT EPISTAXIS WITH BIOFLAVANOIDS: A REVIEW

Teuku Husni T.R1

1Doctoral Study Program of Mathematic Science Aplication, Syiah Kuala University,

Darussalam Banda Aceh 23111

*Corresponding author email: [email protected]

ABSTRACT

Epistaxis is a spontaneous bleeding from the inside of the nose. Epistaxis can occur in all

ages especially in children and the elderly. Epistaxis is estimated to 60% of the

population who had at least one episode of lifetime and only 6% sought medical

help.Epistaxis is very common and is found by many doctors including ENT doctors,

family doctors, and others. Epistaxis is caused by the loss of the nasal mucous membrane

that contains many small blood vessels. Bleeding usually occurs when the mucosa is

eroded and the vessels become open and then rupture. Mucosal loss will be accompanied

by injury to the blood vessels that can cause bleeding. Complementary medicine may

also be given to patients with epistaxis. Traditional Chinese medicine has also performed

acupressure and the use of diet / herbal medicines to treat epistaxis. One supplement that

can help prevent and treat epistaxis is bioflavonoids. Bioflavonoids (or flavonoids) are

plant substances that give color to many fruits and vegetables.

Keywords: Epistaxis, flavonoid, herbs.


SUBJECTIVE WORK FATIGUE AND RELATED FACTORS ON

SILUNGKANG WEAVERS

Aria Gusti1* and Tria Ananda1

1Faculty of Public Health, Andalas University, Padang 25121, Indonesia


ABSTRACT

Silungkang weavers generally work with standing and often bend over long periods of

time which can lead to fatigue and health problems. The objective of this research is to

know the factors related to subjective work fatigue on the weaving workers in Silungkang

Village West Sumatra. The method of this research is analytic observational with cross

sectional study design. The population in this study is the entire workforce of silungkang

weaving. Data were collected using questionnaire and observation method and processed

using chi-square statistical test with 95% confidence interval. The result showed that

60.4% of workers were fatigue, 52.1% of workers had heavy workload, 77.1% were

laborers with long service period, and 75% work with non ergonomic attitude. There is

a relationship between workload (p = 0,009) and work attitude (p = 0,001) with subjective

fatigue. There is no relationship between period of service (p = 0,448) with subjective

work fatigue. There is a relationship between workload and work attitude with subjective

work fatigue on Silungkang Weavers. It is expected the industry to do the control effort

by giving the training about the ergonomic work attitude while doing the job and

stretching at the beginning of feeling sore on the body.

Keywords: subjective, work fatigue, weaver.


PSYCHOLOGICAL WELL-BEING AMONG SMOKERS’ ADOLESCENCE

Fithria1*, Teuku Tahlil2, Adlim3, Syarifah Rauzatul Jannah4, Darmawati5, Cut

Dirna Armanda6

1Mathematics and Applied Science, Syiah Kuala University/Family Nursing

Department, Faculty of Nursing, Syiah Kuala University, Banda Aceh, Indonesia. 2Community Nursing Department, Faculty of Nursing, Syiah Kuala University, Banda

Aceh, Indonesia. 3Chemical Education Department, Faculty of Educational Science, Syiah Kuala

University, Banda Aceh, Indonesia. 4Psychiatry and Mental Health Nursing Department, Faculty of Nursing, Syiah Kuala

University, Banda Aceh, Indonesia. 5Maternity Nursing Department, Faculty of Nursing, Syiah Kuala University, Banda

Aceh, Indonesia. 6Student of Faculty of Nursing, Syiah Kuala University, Banda Aceh, Indonesia

*Corresponding author e-mail : [email protected]

ABSTRACT

Adolescence is a transition period from childhood to adulthood, therefore, an adolescent

need to adjust with physical and psychological change which occur in this period. This

situation may cause an increasing of anxiety which trigger smoking behavior among

adolescent. Smoking also related to depression which influence individual psychological

well-being. The objective of this study was to identify psychological well-being among

smokers’ adolescence including autonomy, environmental mastery, personality

development, positive relationship with others, purpose of life and self-acceptance. It was

a descriptive study, sampling technique by using purposive sampling with 65 respondents

in Senior High School. Data was collected by using questionnaire. The study showed that

psychological well-being among smokers’ adolescent was low (70,8%). Then, the study

also indicated that respondent has high autonomy (55,4%) but low environmental

mastery (53,8%), low personality development (55,4%), low positive relationship with

others (55,4%), low purpose of life (55,4%) and low self-acceptance (55,4%). This study find out that smoker adolescent has low psychological well-being. It is recommended to

teacher for building relationship with parents in assessing adolescent problems and teach

them how to cope with the problem and how to minimized anxiety during adolescence,

so they will not smoke as a coping strategy when facing with a stressful life event.

Keywords: adolescent, smoker, psychological, well-being.



DIVERSITY AND DISTRIBUTION OF FISHES IN KRUENG SABEE RIVER,

ACEH JAYA, INDONESIA

Muhammad Nasir1,2*, Farah Aulia Putri1, Raudhatul Ulfa1, Mardianti1, Firdus

Firdus1 , Munira3, Zainal Abidin Muchlisin4, Saiful5 and Suhendrayatna6

1Departement of Biology, Syiah Kuala University, Banda Aceh 23111, Indonesia 2Graduate School of Mathematics and Applied Science, Syiah Kuala University, Banda

Aceh 23111, Indonesia 3Department of Pharmacy, Health Polytechnic Aceh, Banda Aceh 23352, Indonesia

4Faculty of Marine and Fisheries, Syiah Kuala University, Banda Aceh 23111,

Indonesia 5Departement of Chemistry, Syiah Kuala University, Banda Aceh 23111, Indonesia

6Departement of Chemical Engineering, Syiah Kuala University, Banda Aceh 23111,

Indonesia


ABSTRACT

The research about fish fauna has conducted to assess the impact of environmental

variation of Krueng Sabee river. Fish samples were taken at three stations namely

upstream, downstream and swamp around downstream. The fishes were collected by

using gill-net and fish trap. The surveys performed at each site during this survey resulted

that total 265 individuals belonging 17 families 24 species were found. The Cyprinidae

Family has the highest species (6 species). Diversity index showed a lower value (1.47)

in downstream site with high dominance index, and on the contrary, high value (2.57)

appeared in site swamp with low dominance index. From the analysis of community

structures that more fish species live downstream than in the upstream, particularly the

highest species in the swamp around downstream. Generally, Krueng Sabee community

is very careful to consume fish because this area recently rampant pollution with illegal

gold mining activities so that the effort of catching and consuming river fish tends to be

low.

Keywords: Cyprinidae, fish fauna, gold mining, Krueng Sabee.


ANTIBACTERIAL ACTIVITY OF Magnolia alba FLOWERS EXTRACTS

ON Staphylococcus epidermidis AND Staphylococcus aureus

Khairan Khairan1*, Soraya Septiya1, Murniana2

1 Department of Pharmacy, Faculty Mathematics and Natural Sciences, Syiah Kuala

University, Banda Aceh 23111, Indonesia 2 Department of Chemistry, Faculty Mathematics and Natural Sciences, Syiah Kuala

University, Banda Aceh 23111, Indonesia


ABSTRACT

The white champaca (Magnolia alba) plant has been reported possess antioxidant and

antimicrobial activity. The aim of this study is to investigate the antibacterial activities

of n-hexane, ethyl acetate, and methanolic Magnolia alba flowers extract on

Staphylococcus epidermidis and Staphylococcus aureus. In this study, we also determine

the secondary metabolites of the extracts by the phytochemical screening assay. The

antibacterial activities of the Magnolia alba flowers extracts were determined by Kirby-

Bauer diffusion method. The phytochemical screening assay showed that n-hexane

extract contains of flavonoids, terpenoids, and steroid, while the ethyl acetate and

methanolic extracts contains of alkaloids, flavonoids, terpenoids, and steroid. The

antibacterial activities of the n-hexane, ethyl acetate, and methanolic Magnolia alba

flowers extracts were determined at four different concentrations of 5, 10, 20, and 50%.

The antibacterial activities showed that n-hexane extract has no activity against

Staphylococcus epidermidis and Staphylococcus aureus. Meanwhile, ethyl acetate and

methanolic extracts have antibacterial activities against Staphylococcus epidermidis and

Staphylococcus aureus. The diameter zones of inhibition exhibited by the ethyl acetate

extract against Staphylococcus epidermidis and Staphylococcus aureus were ranged

between 10.45 - 21.03 mm and 10.26 - 26.13 mm respectively. Meantime, the diameter

zones of inhibition exhibited by the methanolic extract against Staphylococcus

epidermidis ranged between 11.96 mm and 18.01 mm and against Staphylococcus aureus

ranged between 7.23 mm and 13.9 mm. In conclussion, the ethyl acetate Magnolia alba

flowers extract was gave higher antibacterial activitiy against Staphylococcus

epidermidis and Staphylococcus aureus.

Keywords: Magnolia alba, antibacterial activity, Staphylococcus epidermidis and

Staphylococcus aureus.


COMBINED EFFECT OF STREPTOMYCIN AND SWEET ORANGE

ESSENTIAL OIL TO MEMBRANE AND ACROSOME INTEGRITY BOER

GOAT FROZEN SEMEN

Sukma Aditya Sitepu1* and Julia Marisa2

1 Department of Animal Husbandry, Faculty of Sains and Technology, Pembangunan

Panca Budi University, Medan 20122, Indonesia. 2 Department of Agroecotechnology, Faculty of Sains and Technology, Pembangunan

Panca Budi University, Medan 20122, Indonesia


ABSTRACT

One of factors that cause a bad quality of Boer Goat frozen semen is the growth of

bacterial. This can be overcome by adding antibiotics such as streptomycin. To further

suppress the growth of bacteria can be added other ingredients that contain antibacterials

such as sweet orange essential oil. The purpose of this research is to know the percentage

value of Membrane Integrity and Acrosome Integrity on Boer Goat frozen semen with

addition sweet orange essential oil and streptomycin. The method used was experimental

using Completely Randomized Design with 5 treatments and 5 replications. The

treatment in this research is addition 0%, 0,25%; 0.5%; 0.75% and 1% sweet orange

essential oil on tris yolk and streptomycin extender. The results showed the best treatment

addition combination streptomycin and sweet orange essential oil to percentage

Membrane Integrity and Acrosome Integrity is increase 1% sweet orange essential oil.

Keywords: Boer Goat, essential oil, frozen semen, streptomycin, sweet orange.


POTENCY ANTIOXIDANT COMPOUNDS OF INDIAN GOOSEBERRY

(Phyllanthus emblica) LEAVES AS HERBAL TEA

Mailisa1*, Cut Meliana1,Cut Maysura Hanum2, Yanti Meldasari Lubis1, Novia

Mehra Erfiza1, and Heru Prono Widayat1

1Department of Agricultural Product Technology, Agriculture Faculty, Syiah Kuala

University, Banda Aceh 23111, Indonesia 2Department of Physical Education, Teaching and Education Science Faculty, Syiah

Kuala University, Banda Aceh 23111, Indonesia


ABSTRACT

Indian gooseberry leaves (Phyllanthus emblica) have been used as traditional medicine

to treat a variety of diseases. The leaves are dried and brewed to produce herbal tea.

Methanolic extract of the leaves contains high of antioxidant components, such as

flavonoids, alkaloids, coumarins, dihydrochalcones, flavones, gallic tannins, glycosides,

phenols and triterpenoids. Therefore, the leaves extract have antioxidant potency as

herbal tea. The purpose of this study is to determine the effect of fermentation and drying

methods during Indian gooseberry leaves tea processing on antioxidant content, water

content and ash content of the tea. The study is designed with Randomized Block Design

factorial, consisted of 2 factors. The first factor is fermentation time (0, 60, 90 and 120

minutes) and the second factor is drying methods (indirect sun-drying and roasting

method). The experiment is carried out in triplicate. Water content of the herbal tea is

6,08% and ash content of the tea is 3,79%. Based on the result of qualitative analysis by

FTIR spectroscopy method, FTIR spectra of the tea and the brewed tea indicate the

presence of several functional groups of antioxidant components. The spectra showed

OH group strecthing at 3327 and 3282 cm-1 and carbonyl group (C=C) stretching of

aliphatic or aromatic at 1635 cm-1 indicated feature of flavonoid and flavone compounds.

In addition, the spectra provide stretching of C–O group at 1021-1219 cm-1 indicated

phenol compounds. Results showed that the highest antioxidant activity of the tea was

provided by indirect sun-drying method and the fermentation 0 minutes (83,17%) and

the lowest antioxidant activity of the tea was given by roasted drying method and the

fermentation 120 minutes (49,07%). The highest total phenol of the tea was provided by

roasted method and fermentation 0 minutes (32,43 mg/L), while the lowest total fenol of

the tea was given by indirect sun-drying method and the fermentation 0 minutes (13,89

mg/L).

Keywords: antioxidant, flavonoid, herbal tea, Ind ian gooseberry, phenol, Phyllanthus

emblica.



TAXONOMY OF THE GENUS Longipeditermes HOLMGREN

(TERMITIDAE: NASUTITERMITINAE) FROM THE SUNDA REGION,

SOUTHEAST ASIA

Syaukani Syaukani1*

, Graham J Thompson2, Seiki Yamane3, Ahmad Sofiman

Othman4, Samingan Samingan

5, Djufri Djufri5, Muhammad Ali

5, Hasanuddin

Hasanuddin5, Husni Husni6

1Biology Department, Faculty of Mathematics and Natural Science, Syiah Kuala

University Darussalam 23111, Banda Aceh, Indonesia 2 Department of Biology, Western University, 1151 Richmond Road North, London

N6A 5B7, Ontario, Canada 3Kagoshima University Museum, Korimoto 1-21-30, Kagoshima-shi, 890-0065,

Japan 4Molecular Ecology Laboratory, School l of Biological Science, Universiti Sains

Malaysia, 11800 Penang, Malaysia. 5Biology Department, Faculty of Teacher Training and Education, Syiah Kuala

University Darussalam 23111, Banda Aceh, Indonesia

6Plant Protection Department, Faculty of Agriculture, Syiah Kuala University

Darussalam 23111, Banda Aceh, Indonesia


ABSTRACT

During 1998 to 2016 we conducted field surveys on termites thirteen times in the

Sundaland area. Examining more than 200 colonies of the genus Longipeditemres from

swamp, lowland, sub- alpine and alpine forest habitats in Sumatra, Borneo and the

Malay Peninsula. We identified two species, Longipeditemres longipes Holmgren and

L. kistneri Akhtar and Ahmad. These are relatively easy to distinguish based on

differences in coloration and condition of the soldier caste head capsule. For each

species, we provide descriptions of the major soldiers and the workers, including color

photographs of diagnostic features. In addition, we suggest that the distribution of L.

kistneri is limited to the islands of Java and Sumatra, while L. longipes is concentrated

in the Sundalandarea, i.e., Java, Borneo, Sumatra and the Malay Peninsula. Both

species appear to be absent on other small islands that we surveyed. Furthermore, we

suggest that Longipeditermes kitsneri may prefer higher altitudes (above 1000 m)

than L. longipes, which instead shows affinity for lowland rain forests. Finally, we

provide a morphological key to the species of Longipeditermes.

Keywords: Taxonomy, termite, Longipeditermes, Sunda region, Southeast Asia.



DIVERSITY OF ARTHROPODS AT THE ARABICA COFFEE PLANTATION

IN ATANG JUNGKET VILLAGE, ACEH TENGAH REGENCY

Muhammad Sayuthi1*, Hasnah1, Alfian Rusdy1, Susanna1, Auliani1

1Plant Protection Department, Faculty of Agriculture, Syiah Kuala University, Banda


*Corresponding author e-mail: [email protected].

ABSTRACT

This research was conducted on an arabica coffee plantation that was organically

managed in Atang Jungket village, Bies District, Central Aceh Regency. Sampling using

purposive sampling method with 5 hectare land area at altitude 1400 m above sea level.

The results showed that arthropods found in arabica coffee plantations consist of 2

classes, 12 orders, and 72 families. The order of Hymenoptera was the dominant order

(39.72%), followed by Diptera (34.72%), Araneae (9.46%), Coleoptera (8.06%) and

other orders (Hemiptera, Blatodea, Homoptera, Lepidoptera, Mantodea, Mecoptera,

Orthoptera and Psocoptera) that is 8.05%. The high abundance of arthropods in an agro-

ecosystem is related to the stability of the environment, where the food chain is still well-

established.

Keywords : Arthropoda, biodiversity, coffee plant.



DENSITY FIGURE OF Aedes spp LARVAE IN JEULINGKE VILLAGE SYIAH

KUALA SUBDISTRICT BANDA ACEH

Farida Athaillah1*

1Department of Clinical Veterinary, Faculty of Veterinary Medicine, University of Syiah Kuala,

Darussalam, Banda Aceh 23111, Indonesia


ABSTRACT

This study was aimed to determine the level of Density Figure of Aedes spp mosquito larvae with

parameter House Index (HI), Container Index (CI), and Breteau Index (BI) at Jeulingke Village,

Syiah Kuala Subdistrict, Banda Aceh. This research was conducted by using Single Larva

Method. Single Larvae Method is a method used to take a single larva by using a plastic scoop

on each container that is found to have a larva and visually observed by using a flashlight. The

sample used consisted of 120 houses taken randomly from 6 hamlets. The larval data were

obtained from various types of containers tabulated into tabular form, then the larvae index was

calculated to determine the density of the larvae based on the Density figure criteria. The results

showed that from 120 houses found 702 containers in Jeulingke Village with 20 positive larval

houses and 20 containers that positively contained larvae such as 19 bath containers and used

tires by 1 container so that the index of larvae obtained with House Index is 17% , Container

Index of 3%, Breteau Index 20, so as to obtain Density Figure value in the range of numbers 2-

4. The results show that the Density Figure in Jeulingke Village is in the medium category

Keywords: Aedes spp, mosquito larvae, House Index, Container Index, Breteau Index.


COMPARISON OF COX MODELS IN DETECTING FACTORS AFFECTING

HEALING RATE OF DENGUE HEMORRHAGIC FEVER

Miftahuddin1* and Inas Salsabila1

1Department of Statistics, Faculty of Mathematics and Sciences, Syiah Kuala

University

Jln. Teuku Nyak Arief Darussalam, Banda Aceh, Aceh, 23111, Indonesia


ABSTRACT

Dengue Hemorrhagic Fever (DHF) is an epidemic of disease that usually becomes a

benchmark of good or bad condition of the environment and health facilities of a region.

When the disease is outbreak and does not get serious treatment, it will cause death. One

of the first steps that can be done to deal with this disease is to know the factors that

affect the healing rate of DHF patients. This study aims to detect factors affecting the

healing rate of DHF patients by using Cox regression analysis based on Cox model

family, such as Cox Proportional Hazard (CPH) model, extended Cox model with one

and two heaviside function, and Stratified Cox (SC) model and get best model for this

study. The data used is secondary data consisting of 107 in-patient DHF period January-

December 2016 at Regional General Hospital dr. Zainoel Abidin Banda Aceh. Based on

CPH model, the variable that significantly affect the patient's healing rate is Age. Based

on the extended Cox model with one heaviside function, the variables that significantly

affect the patient's healing rate are Age, Sex, Number of Platelets, Clinical Degrees III

and Number of Leukocytes multiplied by the time function. Based on the extended Cox

model with two heaviside functions, the variables that significantly affect the patient's

healing rate are Age, Sex, Number of Platelets, Clinical Degrees III and Number of

Leucocytes multiplied by second time function. Based on the SC model, there are no

variables that significantly affect the patient's healing rate. The best model based on

Akaike Information Criterion (AIC) value is the SC model.

Keywords: AIC, CPH, DHF, extended Cox, SC.



PREPARATION OF 3-DIMETHYLCARBAMOYL EMODIN AND ITS

CYTOTOXIC EVALUATION AGAINST HepG2 CELL LINES

Firdayani1*, Churiyah1 and Billy Witanto2

1Center for Pharmaceutical and Medical Technology, Agency for The Assessment and

Application of Technology, Tangerang Selatan, 15314, Indonesia 2Department of Biology, Surya University, Tangerang Selatan, 15143, Indonesia


ABSTRACT

1,3,8-Trihydroxy-6-methylanthaquinone (emodin) is recognized as an antiproliferative

compound. The aim of study was to evaluate functional of hydroxyl group in emodin in

cytotoxic activity. In this research, emodin was reacted with dimethylcarbamoyl chloride

and K2CO3 to result 3-carbamoyl emodin. These compounds were performed cytotoxic

evaluation against HepG2 cell lines using MTT asssay. Results showed that 3-carbamoyl

emodin is less cytotoxic than emodin. It is indicated that the hydroxy group at C3 position

of emodin is a functional group which has role in its antiproliferative activity.

Keywords: carbamoyl, cytotoxic, emodin, HepG2.


REMEDIAL LEARNING BASED SCAFFOLDING FOR STUDENTS

INCREASE LOW

Rizqa Rahmati1*, Anwar1, Anizar Ahmad3

1Department of Mathematics Education, Faculty of Teacher Training and Education,

Syiah Kuala University, Banda Aceh 23111, Indonesia 2Department of Early Childhood Education, Faculty of Teacher Training and

Education, Syiah Kuala University, Banda Aceh 23111, Indonesia


ABSTRACT

The Indonesian curriculum mandates the achievement of learning completeness for every

student, teachers should provide remedial to low-ability students. However, at that time

the teacher did not have enough time to provide remedial during the learning process.

Therefore, it is necessary for the teacher to provide remedial outside the Lesson Time,

for example by remedial using scaffolding strategy after the learning takes place. This

study aims to describe the ability of low-ability students after being given scaffolding

through remedial learning on the material of building a flat side space. The research was

conducted in Grade VIII SMPN Unggul Tunas Nusa Aceh Barat Daya. The subjects

chosen based on the results of the teacher's tests found six low-skilled subjects, two non-

learning subjects, two diligent study lessons, and two lessons with no lessons learned.

Data collection techniques are conducted through obeservation, test questions, and

interview guidelines. Furthermore obeservasi data is described using a qualitative

approach, ie the problems that are done. The results showed that remedial learning based

on scaffolding made the students able to do the questions. Therefore, scaffolding

strategies in remedial learning can be undertaken to overcome low-ability difficulties in

the understanding of Lesson materials.

Keywords: Remedial, Scaffolding, Low-Capacity Student.


ANTIHYPERGLYCEMIC POTENTIAL OF HELMINTHOSTACHYS

ZEYLANICA LEAVES EXTRACT IN DIABETIC RATS

Erlidawati Erlidawati1, Musri Musman1, Safrida Safrida1*

1Department of Chemistry Education, Teacher Training and Education Faculty, Syiah

Kuala University, Darussalam-Banda Aceh 23111, Indonesia

Corresponding author e-mail: [email protected]

ABSTRACT

Helminthostachys zeylanica has been traditionally used to treat diabetes mellitus in Aceh.

It contains alkaloids, flavonoids, tannins and polyphenolic. This study was designed to

determine the antihyperglycemic potential of H. zeylanica leaves extract in diabetic rats

and to compare the natural product of H. zeylanica leaves extract with metformin. A

completely randomized design was used for the experiment which consisted of 6

treatment groups, each consisting of 5 rats. The treated extract at 100, 300 and 500 mg/Kg

body weight administered to the Alloxan-induced diabetic rats and compared to the

reference of metformin (65 mg/Kg body weight). The two-factor ANOVA was used to

determine the interaction effect between the extract and the blood glucose level of Rat by

utilizing GraphPad Prism 7 software. Histopathological investigations performed the

evidence that the extract could improve pancreatic β-cells and depresses necrosis or

apoptosis of pancreatic β-cells in the islet cells. the recommended dose was 300 mg/Kg

body weight to be applied in order to provide a significant effect on reducing blood sugar

level and enlightening pancreatic β-cells. This scientific evidence showed that the

ethanolic extract of H. zeylanica has an antihyperglycemic potential, and therefore, it can

be utilized to deal with type 2 diabetes. Our findings support the use of this plant as a

treatment for diabetes and other diseases.

Keywords: Helminthostachys zeylanica, diabetic rats, alloxan, antihyperglycemic.



IMPACTS OF COFFEE VARIETIES AND PROCESSING PRACTICES ON

THE PHYSICAL AND SENSORY CHARACTERISTIC OF GAYO ARABICA

SPECIALTY COFFEE

Yusya' Abubakar1*, Dian Hasni1, Murna Muzaifa1, Heru Prono Widayat1, Ismail

Sulaiman2, Mahdi Mahdi3

1Department of Agricultural Product Technology, Agriculture Faculty, Syiah Kuala

University, Banda Aceh 23111, Indonesia 2Faculty of Economic and Business, Syiah Kuala University, Banda Aceh 23111,

Indonesia 3Gayo Cupper Team, Takengon, Indonesia


ABSTRACT

Sensory characteristics nowadays are considered as basic requirement of coffee quality,

which determined its commercial value later on. Gayo Arabica coffee has been

considered as specialty coffee due to it complexities in the whole treatment from farm to

the cup of coffee beverage. However, their sensory characteristics varies depend on its

local varieties and the processing practices in Gayo Highland areas. This study aims to

determine the impacts of the above factors towards physical and sensory characteristics

of Gayo Arabica coffee. The research used Randomized Block Design with two factors

and three repetitions with total 36 experiments. The first factor is local varieties named

TimTim, Borbor, Ateng Super and Multivarieties (mixvarieties). The second factor is

processing practices named full-wash, semi-wash and honey process. The measured

parameters are moisture contents and cupping quality based on SCAA standard. SCAA

Coffee cupping quality assesses ten coffee attributes by Qualitative Descriptive Analysis

for food sensory. The ANOVA showed that local variety factor has significantly

influenced (P≤0.01) the mentioned attributes which are fragrance, flavor, body, overall

and total score of coffee beverage, whereas the processing practices has only significantly

influenced (P≤0.01) balance, body and overall attributes of coffee beverage. The

interaction of both factors showed significant impacts (P≤0.01) towards flavor, acidity

and balance attributes. In detail, Ateng Super variety tends to obtain high score of

cupping attributes whilst full wash and semi wash only has slight differences. It is can be

concluded that all experiments produced specialty coffee based on SCAA cupping test,

with the total score are ranging from 83.67 to 85.83. Ateng Super variety (local variety)

obtained the highest score among others (85.36±0.14) and full-wash processing produced

the highest cupping quality compared to others (84.79±0.03). The Q-grader also remarks

that Gayo Arabica coffee has distinguished flavor such as chocolate, dark-chocolate,

caramel, nutty and spicy in all experiments. However several unpleasant remarks also

appeared in honey process practices such as sour, over-ripe, slightly aged and fermented.

Keywords: Arabica coffee, cupping quality, Gayo Higland, SCAA, QDA.


THE EFFECT OF TINOSPORA CRISPA ON ANTI OXIDANT STATUS IN

STREPTOZOTOCIN INDUCED DIABETIC RATS

Sarah Firdausa 1, Maung Maung Cho2, Khin Maung Maung2, Nilar Aung2,

Norsidah Kuzaifah2

1Faculty of Medicine, Syiah Kuala University 2Kulliyyah of Medicine, International Islamic University Malaysia


ABSTRACT

Diabetes is a leading cause of cell oxidative stress which can lead to toxic effects on

structure and function of organs, including β-cell in pancreas. Islet cells of pancreas are

among the tissues that have the lowest level of antioxidant defense. In chronic

hyperglycemic state, a number of reactive oxygen species accumulate in an excess

amount and cause chronic oxidative stress in the islet cell. This study aimed to investigate

the effect of Tinosporacrispa aqueous extract (TC) on oxidant status tatus in

streptozotocin (STZ)-induced diabetic rats. Fifty mg/kgbw of STZ was intraperitoneally

induced to Sprague-Dawley rats. The animals were divided into five groups (n=6);

normal (N), normal TC treated (NT), diabetic (D), diabetic TC treated (DT), and diabetic

treated with Vitamin E (DE), respectively. Treatment was delivered for 4 weeks and

blood sample were withdrawn for parameters measurement. The data among groups were

compared using one way ANOVA test, while paired T test was used to analyse the

differences between data of pre and post treatment. In normal groups, the antioxidant and

oxidative stress level of N group did not differ noticeably with NT group. In diabetic

groups, the antioxidant status in DT rats showed that TC might prevent a decrease of

superoxide dismutase level which was reduced in other diabetic groups. It also increased

the glutathione peroxidase enzymes in animals TC treated (NT and DT). Oxidative stress

level (lipid hydroperoxide and isoprostane) went up substantially in group D and no

significant changes in other groups. These results showed that TC might protect diabetic

subjects from reactive oxigen species generation by enhanced anti-oxidant enzymes

level.

Keywords: Antioxidant, oxidative stress, streptozotocin, Tinospora crispa.


OPTIMIZATION OF MINIMAL MEDIUM FORMULATION TO ENHANCE

ACTIVITY OF IOX (IODIDE-OXIDATION ENZYME) SYSTEM AS A NOVEL

ANTIMICROBIAL-BASED ENZYME

Tri Yuliana1, Seigo Amachi2, Efri Mardawati3

1Departement of Food Technology, FTIP, Padjadjaran University, Bandung, Indonesia

2Graduate School of Horticulture, Chiba University, Matsudo City, Chiba, Japan 3Department of Agroindustrial Technology, FTIP, Padjadjaran University, Bandung,

Indonesia


ABSTRACT

A novel enzyme, iodide-oxidizing enzyme (IOX) has been isolated from a marine

bacterium Iodidimonas sp. Q-1. Biochemical characterizations of IOX showed that it is

one of multicopper oxidases (MCO) with laccase-like properties. IOX comprising

potassium iodide (IOX system) has an antimicrobial effect with the result as a potential

a new disinfectant in food industry. In this study, the IOX system was examined with

the aim to optimize of culture condition to enhance its production. Various combination

of Minimal Medium Broth (MMB) which suitable for strain Q-1 growth were evaluated

to find out the highest of IOX enzyme activity with simpler formulation than marine

medium. MMB XII (resulted the highest of IOX system activity (7526 mU mL-1),

followed by MMB V (7128 mU mL-1) and MMB IV (6827 mU mL-1), respectively.

Nitrogen sources including organic and anorganic were optimized into MMB XII to

evaluate the effects of nitrogen sources to enhance IOX activity. Various inducers

involved in increased IOX activity were determined, while copper (40 µM) within 48 h

increased the highest of IOX activity. These results suggested that the formulation of

MMB XII containing copper 40 µM was effective as a simple medium formulation to

enhance activity of IOX system.

Keywords: IOX system, enzyme activity, optimization, minimal medium.



UTILIZATION OF LOCAL FISH MEAL WASTE AS A SUBSTITUTE

PROTEIN SOURCE TO REDUCE THE COST OF BROILER DIET

Aman Yaman1*

1Department of Animal Husbandry, Agriculture Faculty, Syiah Kuala University,

Banda Aceh 23111, Indonesia


ABSTRACT

This research was based on an effort to reduce a production costs of commercial broilerby

looking for an alternative material to substitute a commercial fish meal which isexpensive

and difficult to obtain as the main ingredients for commercial diet. One of thealternative

material was a local fish waste which is widely available, cheap and has ahigh protein

content as a protein source of broiler diet. This research was conducted atthe Animal

Husbandry Field Laboratory (LLP)-University of Syiah Kuala, Banda Aceh for30 days.

There were 80 broiler chick was fed by 4 different types of diet contained aflour of local

fish waste. The treatment diet was prepared on the difference in the levelof local fish

waste flour content, which were: 0% (R1), 4% (R2), 8% (R3), and 12%(R3)% in the

ration. The research design used was a Completely Randomized Design(CRD) consisting

of 4 treatments and 4 replications consisting of 5 chicks. Theparameters measured were

final body weight, weight gain, feed consumption, feedconversion and fed cost. The data

obtained were analyzed by analysis of variance. Theresults showed that the subtituation

of local fish waste in diet had a high significantlyeffect (P <0.01) on the final body

weight, average weight gain, feedconsumption, andfeed conversion of broiler. An

increase in the level of local fish waste flour in diet caused the final body weight, weight

gain, feed consumption, and feed conversion of broilerwas higher than that of in control

diet. The results of this study also showed thatincreasing levels of local fish waste flour

in diet decreased fed cost between 20-40%compared to using a commercial fish meal.

It was concluded that the use of local flourwaste to subtitute a commercial fish meal has

a very beneficial both from theproduction of broiler and the cost of feed which reduced

the feed cost to be cheaper.The result will be very useful for small-scale of broiler

farmers to increase a profits of broiler business.

Keywords: fish meal, protein, broiler, production.


PATOBIOLOGY OF CHRONIC PAIN; WHAT IS THE DIFFERENT FROM

PATOBIOLOGY OF ACUTE PAIN?

Endang Mutiawati

Department of Neurology, Medicine Faculty, Syiah Kuala University,



ABSTRACT

Chronic pain causes problems for the sufferer because it disturbs the productivity and

quality of life. The number of chronic pain sufferers in the United States reaches 100

million people and annually spends 500 billion US dollars. The International Association

for the Study of Pain (IASP) defines chronic pain as "painless apperently biological value

that has persisted beyond the normal tissue healing time". At present chronic pain

management is a continuation of acute pain therapy, whereas in terms of patobiology

there is a fundamental difference, therefore the treatment of chronic pain that many

unsuccessful. This paper is an article review of an updated journal that discusses the

patobiology of chronic pain in the understanding of molecular aspects that causes

prolonged pain. The presence of prolonged pain indicates the complexity of the

associated tissue. The role of chronic pain is not only caused by the prolonged destruction

of tissue, but also the linkage of pain-nerve fibers to the brain as centers of pain, cognitive

and emotional perception. This is a challenge that must be continuously explored.

Chronic pain patobiology is still not fully known, more in-depth biomolecular research

is needed. The number of organs or tissues involved becomes one of the reasons for the

complexity of knowledge about chronic pain and this is the cause of failure of treatment.

Keywords: Acute, chronic, pain, patobiology.


PHYSICOCHEMICAL CHARACTERIZATION OF OIL FROM ROATED

COFFEE

Sukma Rizki Ariga1*, Yuliani Aisyah1, Anshar Patria1, Normalina Arpi1 and Dewi

Yunita1

1Department of Agricultural Product Technology, Faculty of Agriculture,

Syiah Kuala University, 23111, Indonesia


ABSTRACT

This study aims to determine the physical and chemical characteristics of coffee oil

extracted using maceration method by varying the temperature and time of roasting

coffee beans. This study used Randomized Block Design (RBD) Factorial with the

roasting temperature of coffee (S) consisting of three levels, namely S1 = 1650C (light),

S2 = 1850C (medium), S3 = 1950C (dark), and the roasting time consisted of three the

level is L1 = 20 minutes, L2 = 40 minutes and L3 = 60 minutes. The results showed that

the yield of coffee oil produced was 5.7% -16.0%, specific gravity 0.93-0.97,

saponification number 185.61-188.70 mgKOH/g, and acid number 1.30- 2.87 mg/g. The

results of the analysis of the composition of coffee oil using chromatography gas mass

spectra, the dominant fatty acids in coffee oil are palmitic acid, palmitoleic acid, stearic

acid, linoleic acid and arachidic acid. The best treatment was obtained in coffee oil with

a roasting temperature of 1950C and a roasting time of 20 minutes which had the highest

yield of 15.3%, specific gravity 0.97, saponification number 186.13 mg KOH/g, and acid

number 1.60 mg/g.

Keywords: coffee oil, roasted coffee, maceration.


POMEGRANATE PEEL POTENCY AS PREVENTIVE AGENT OF

RHEUMATOID ARTHRITIS

Doti Wahyuningsih1*, Annisa Amilia2, Asri Cahyaningrum2, Laili Cinthianur

Kurniasari2, Meilano Setiawan Amiruddin2

1Biochemistry Department, Faculty of Medicine, Malang Islamic University,

Jalan MT. Haryono 193, Malang 65144, Indonesia 2Medical Profession Education, Faculty of Medicine, Malang Islamic University,

Jalan MT Haryono 193, Malang 65144, Indonesia


ABSTRACT

Rheumatoid arthritis (RA) is joint disease which the patogenesis involve gen and

environment induce oxidative stress. The disease affects the daily life activities because

the joint destruction is permanent. Pomegranate peel contains many active subtances with

antioxidative properties. The present study evaluated the serum TNF-α and IL-6 ,

synovial MMP-9, and arthritis score (AS) of RA rats models treated with ethanolic 80%

extract of pomegranate peel (EPP). Three groups of male Lewis rats (each 5), 8 weeks,

200 g received 80 mg, 160 mg, and 320 mg of EPP/day respectively, in alternate day

for 60 days. On day 30th the rats were subcutanously injected with 0,1 ml

mycobacterium-complete Freund’s adjuvant (1mg/mL) on right hind paws. On day 60th

the intracardiac blood were aspirated and the paws were amputated. The TNF-α and IL-

6 were measured by ELISA assay, MMP-9 was immunohistochemistry processed, and

AS was evaluated by arthritic assessment score of Smit. Kruskall Wallis followed Mann

Whitney U test were used to analyze the data. The value of p< 0.05 was significant. The

study revealed the dose 320 mg of EPP significantly reduced serum TNF-α and IL-6,

and synovial MMP-9 of arthritic rats compared with those receiving no EPP. The dose is

able to reduced synovial MMP-9 approximate that of healthy rats (p>0.05). The given

doses of EPP sligthly improve the AS. The results indicate the EPP may potensial to be

developed as preventive agent of rheumatoid arthritis.

Keywords. Arthritic index, IL-6, MMP-9, Pomegranate, TNF-α.

mailto:*[email protected]


THE ROLE OF PLANT GENETIC RESOURCES IN ENCOUNTERING

CLIMATE CHANGE CHALLENGE

Rita Andini1*, M. Ikhsan Sulaiman2, Evan Febriansyah1, Ashabul Anhar1

1Forestry Department, Faculty of Agriculture, Syiah Kuala University, Darussalam,

Banda Aceh - 23111, Indonesia 2Post Harvest Technology Department, Faculty of Agriculture, Syiah Kuala University,

Tgk. Hasan Krueng Kalee, Darussalam, Banda Aceh - 23111, Indonesia


ABSTRACT

The world is encountering a global threat: climate change. It is estimated that the air average air

temperatures will raise between 3.7oC up to 7.8oC by 2100. The possible impacts will vary,

however, agriculture will be adversely affected marked with yield loss of staple crops (rice and

maize) as well as altered post harvest quality of horticulture products. On the other hand, the

world food and agriculture organization (UN-FAO) has set a target ‘zero hunger by 2030’, despite

the five big challenges ahead: i) protacted conflict, ii) growing inequality, iii) rapid urbanization,

iv) the economic challenges: rising trade tensions and elevated debt levels, v) drought and natural

disasters. The existing plant genetic resources, particularly the wild, neglected, and underutilized

species has a great role and bears big potential to be exploited and targetted to achieve food and

nutrition security especially in the regions with high number of population and malnutrition

problem such as in Asia and sub-Saharan regions. However, a key to future and sustainable crop

production lies in the collection of crop and their wild relatives stored in ex-situ, or in-situ. This

paper aims to explain the importance of plant genetic resources as well as the potential of some

underutilized crops closely attributed with drought resistence, such as sorghum (Sorghum bicolor

L. Moench), amaranth (Amaranthus sp.). These crops bear potential to support national food

security program.

Keywords: biodiversity, food security, orphan crop, underutilized crop.


SEX AND BODY CONDITION ARE CORRELATED TO PREVALENCE AND

PARASITIC INTENSITY OF TREMATODE INFECTION IN ACEH CATTLE

Muhammad Hambal1, Rizka Ayuni1, Henni Vanda2, Mustafa Sabri3, Farida1

1Laboratory of Veterinary Parasitology, Faculty of Veterinary Medicine, Syiah Kuala

University, Banda Aceh – 23111, Indonesia 2Laboratory of Veterinary Pharmacology, Faculty of Veterinary Medicine, Syiah Kuala

University, Banda Aceh – 23111, Indonesia 3Laboratory of Veterinary Anatomi, Faculty of Veterinary Medicine, Syiah Kuala

University, Banda Aceh – 23111, Indonesia


ABSTRACT

Fasciola gigantica and Paramphistomum spp are two members of trematode helminth

that cause severe economic losses. A study to examine the correlation between the

prevalence of bovine trematode, infection of Fasciola gigantica and Paramphistomum

spp. and its correlation toward Body Condition Score was conducted in Aceh,

Indonesia.Body condition score (BCS) is a parameter to analyze body condition of

animal unit of the 103 cattle, 50 male and 53 females that were slaughtered in Banda

Aceh municipality abattoir were examined. Body Condition Score and number of eggs

coproscopically were analyzed in the laboratory of Veterinary Parasitology, Syiah Kuala

University. Results showed that 41% of F. gigantica prevalence in females was lower

compared to male (72%). The average number of fasciola eggs was low, 2,55/g in

females, while it was slightly higher in males (2,75/g) . The other trematodes,

Paramphistomum spp., exhibited a higher level of prevalence when compared to

Fasciola gigantica. The prevalence of Paramphistomum was higher in female (81%)

than in male (72%) carcasses. Compared to F. gigantica, the average egg counts of

Paramphistomum spp was much higher than F. gigantica per gram faeces. The average

egg counts of Paramphistomum spp was significantly higher in males (127,6 eggs/ gram)

than in female (36,8 eggs/ gram); (P<0,05). Evidence from this study indicates that sex

of the cattle determined the level of prevalence and intensity of Fasciola gigantica.

Female hormone estrogen has the trigger properties of Reticulo Endothelial System

(RES) cells, thus increase the immune system of females (part of discussion should be

eliminated). Although this does not necessarily happened with Paramphistomum.

Regarding the Body Condition Score, the highest prevalence of both trematode is in the

skinny cattle (Score 2 and 3). This explains that, both Fasciola gigantica and

Paramphistomum spp infections are responsible for weight loss in Aceh Cattle.

Keywords: Aceh cattle, Body condition score, F. gigantica, Paramphistomum spp,

parasite intensity.


ANALYSIS RELATIONSHIP BETWEEN PRODUCTION FACTORS WITH

BUSINESS PRODUCTION OF BROILER CHICKEN IN BERINGIN VILLAGE

DELI SERDANG REGENCY

Julia Marisa1* and Sukma Aditya Sitepu2

1 Department of Agroecotechnology, Faculty of Sains and Technology, Pembangunan

Panca Budi University, Medan 20122 Indonesia 2Department of Animal Husbandry, Faculty of Sains and Technology, Pembangunan

Panca Budi University, Medan 20122, Indonesia.


ABSTRACT

One of the parameters to measure the success of a business is the level of profit by means

of efficient utilization of factors production. The combination of the use factors

production in any business is a prerequisite for profit. When managing the business of

broiler livestock, a factor that determines the optimal level of profit and economic

efficiency. The purpose of this study is to analyze the relationship between the area of

business, seeds, feed, medicines and labor with the production of chicken business in

Beringin Village Deli Serdang Regency. This type of research is descriptive research that

explain the condition variable broiler chicken farming. The population in this study is all

broiler breeders on Beringin Village. The sampling method is a census of 30 breeders.

The analysis method is Chi-Square using SPSS 18.0 software. The results showed a

correlation between the area of business, seeds, feed, medicines and labor to production

of broiler chicken business in Beringin Village Deli Serdang with the relationship

between business scale, feed, medicine with production equal to 88,3%, and the

relationship of seed with production equal to 93,5% and the relationship of labor with

production equal to 72,9%.

Keywords : Broiler Chicken, Factor Production, Livestock Business, Production.


OUTCOME CARBAPENEM-RESISTANT ENTEROBACTERIACEAE (CRE)

CLINICAL SPECIMENT ISOLATE IN ZAINOEL ABIDIN GENERAL

HOSPITAL BANDA ACEH YEAR 2017

Zinatul Hayati1*, Syamsul Rizal2, Masralena Siregar3, Wilda Mahdani1, Teuku

Fadrial Karmil4, Ridhia Putri5

1Department of Microbiology, Faculty of Medicine, University of Syiah Kuala,

Darussalam, Banda Aceh 23111, Indonesia 2Department of Surgery, Faculty of Medicine, University of Syiah Kuala, Darussalam,

Banda Aceh 23111, Indonesia 3Department of Internal Medicine, Dr. Zainoel Abidin General Hospital, Banda Aceh

23126, Indonesia 4Department of Clinical Veterinary, Faculty of Veterinary Medicine, University of Syiah Kuala,

Darussalam, Banda Aceh 23111, Indonesia 5Microbiology Laboratory Dr. Zainoel Abidin General Hospital, Banda Aceh 23126

*Corresponding author e-mail: [email protected].

ABSTRACT

Carbapenem-resistant Enterobacteriaceae (CRE) has became health threat because

decreasing antibiotic sensitivity to cure infection patients, with the result that mortality

rate is increased. The objective of this study is to get incidence rate of CRE and sensitivity

pattern Enterobactericiaeae and also patients outcome which infected with CRE in

Zainoel Abidin General Hospital year 2017. Identification and sensitivity test was done

with VITEK® 2 Compact. Patient data collected from medical record. All data was

analyze with univariate. Result from this study is that 164 Enterobactericeae were isolate

from 164 clinical specimen in 6 month. That consisted of 58 isolate (35%) is from

sputum, 45 isolate (27%) from urine, 40 isolate (25%) from pus, 16 isolate (10%) from

blood, vaginal swab and body fluid respectively 3 isolate (2%) and 2 isolate (1%). From

total 164 isolate Enterobacteriaceae found 75 isolate (45,7%) Klebsiella pneumonia species, 72 isolate (43,9%) Escherichia coli species, 6 isolate (3,7%) respectively got

Proteus mirabilis and Enterobacter cloacae species, 3 isolate (1,8%) Enterobacter

aerogenes species, and 1 isolate (0,6%) respectively got Klebsiella oxytoca and

Salmonella sp. Sensitivity test to ward Carbapenem got 145 isolate (88,4%) sensitive and

19 (11,6%) resistant. CRE species isolate found is 12 isolate (63%) Klebsiella

pneumonia, 6 isolate (32%) Escherichia coli, and 1 isolate (5%) Enterobacter aerogenes.

Most clinical diagnose is sepsis and UTI. Average length of stay (LoS) is 10 days. While

treatment got 6 patients (31,6%) died and the rest is fully recover. Summary of this study

is incidence rate of CRE in ZainoelAbidin General Hospital in 2017 is 11,6%. CRE

infection make prolong LoS till dying.

Keywords: Carbapenem-resistant Enterobacteriaceae, culture, sensitivity, outcome.



DENSITY LEVEL, GROWTH PATTERN, AND DISPERSION PATTERN OF

FAUNUS ATER AT REULENG RIVER LEUPUNG ACEH BESAR

Rahmi Agustina1,2*, M. Ali Sarong3, Fredinan Yulianda4, Suhendrayatna5,

Rahmadi6

1Doctoral Program of Mathematics and Science Application of Post Graduate Program

Syiah Kuala University, Darussalam Banda Aceh 23111 Indonesia. 2Departement of Biology, Faculty of Teacher Training and Education, Jabal Ghafur

University Gle Gapui Sigli 24171 Indonesia. 3Departement of Biology,Faculty of Teacher Training and Education Syiah Kuala

University, Darussalam Banda Aceh 23111 Indonesia. 4Department of Water Resources Management Faculty of Fisheries and Marine

Sciences, Bogor Agricultural University, Bogor 16680 Indonesia. 5Department of Chemical Engineering, Faculty of Engineering, Syiah Kuala

University.. Darussalam Banda Aceh 23111 Indonesia. 6Department of Chemical, Faculty of Mathematics and Science, Syiah Kuala

University., Darussalam Banda Aceh 23111 Indonesia.


ABSTRACT

Faunus ater is a snail-like animal known as a gesture in the local community of Aceh

Besar, the community presents it as a perfect flavor of delicacy in several types of cuisine.

This study aims to analyze the density, growth patterns and distribution patterns of

Faunus ater in the Reuleung River, Leupung, Aceh Besar. Observation and retrieval of

Faunus ater were carried out at three stations: station 1 in the upper reaches of the river,

station 2 in the middle of the river, and station 3 downstream of the river. Each consists

of three 1m2 plots. Sampling was done once a month for 3 months, from Februari to April

2017. The population density of Faunus ater was calculated using the formula D = ni/a,

the population structure was analyzed by calculating the dispersion pattern of Faunus

ater using the Morisita Index, while the growth pattern was analyzed by shell length and

data weight. The results showed that the highest density of Faunus ater was found at

station 2 in April 103 individu/m2. Distribution patterns occur in clusters and

uniforms,while the growth patterns are allometrically negative which is characterized by

increasing lengths faster than weight gain.

Keywords: density level, dispersion patterns, Faunus ater, growth patterns, reuleung

rivers.


STEROID LEVEL OF REPEAT BREEDING ACEH CATTLE

SYNCHRONIZED WITH PGF2Α

Cut Nila Thasmi1*, Tongku Nizwan Siregar1, Sri Wahyuni2, Dwinna Aliza3,

Hamdan Hamdan, Budianto Panjaitan4, Nuzul Asmilia1, Husnurrijal Husnurrijal5

1Faculty of Veterinary Medicine, Syiah Kuala University, Banda Aceh 23111,

Indonesia 2Anatomy Laboratory of Veterinary Medicine, Syiah Kuala University, Banda Aceh

23111, Indonesia 3Patology Laboratory of Veterinary Medicine, Syiah Kuala University, Banda Aceh

23111, Indonesia 4Clinical Laboratory of Veterinary Medicine, Syiah Kuala University, Banda Aceh

23111, Indonesia 5Reproduction Laboratory of Veterinary Medicine, Syiah Kuala University, Banda



ABSTRACT

The objective of this research is to determine steroid level of repeat breeding Aceh cattle.

This research included 17 female Aceh cattle, aged 3-5 years, who had been pregnant at

least once. The cows were divided into two groups, fertile cows (n=7) and repeat breeding

cows (n=10). All cows were estrous synchronized by 5 ml PGF2α intramuscularly

(LutalyseTM, Pharmacia & Upjohn Company, Pfizer Inc.) via double injection pattern,

with 11 days interval. Blood collection for progesterone measurement began on the day

of the last PGF2α injection, while the blood sample for estradiol was collected during

standing heat. Steroid analysis was performed by enzyme linked immunosorbent assay

method (ELISA). Injection of the second PGF2α in both treatment groups managed to

induce estrus in 5 cows (71.4%) in fertile cow group, and 9 cows (90.0%) in repeat

breeding cow group. Estradiol level showed insignificant differences (P>0.05) between

fertile cows (110.4±20.1 pg/ml) and repeat breeding cows (101.6±17.4 pg/ml).

Progesterone level showed significant difference (P>0.05) on Day 5 after PGF2α

injection, with 2.88±2.14 ng/ml (fertile cows) and 1.13±0.68 ng/ml (repeat breeding

cows). Repeat breeding Aceh cattle have lower progesterone level on Day 5 after PGF2α

injection compared to fertile cows.

Keywords: Aceh cattle, progesterone, repeat breeding.



THE EFFECT OF ACID AND ENZYMATIC HYDROLYSIS ON XYLITOL

PRODUCTION FROM OIL PALM EMPTY FRUIT BUNCH

Efri Mardawati1*

1Department of Agroindustrial Technology, Padjadjaran University, Bandung 45363,

Indonesia


ABSTRACT

Xylitol is a low-calorie sugar which is used as a sweetener in foods. Xylitol can be

produced from hydrolysis and fermentation of lignocellulosic feedstock like Oil Palm

Empty Fruit Bunch (OPEFB). Hydrolysis of hemicellulose produces xylose which can

be converted to xylitol by fermentation using microbes. Two methods of hydrolysis, acid

hydrolysis, and enzymatic hydrolysis are carried out in this study. The objective of this

study is to evaluate the effects of acid hydrolysis and enzymatic hydrolysis on the

production of xylitol. The pretreatment process is carried out by the heating method at

121 ° C for 15 minutes in the autoclave. Hydrolysis process using sulfuric acid and

xylanase enzyme as catalyst to produce xylose as xylitol feedstock. Microbe used for the

xylitol fermentation was Debaryomyces hansenii. The results show that acid hydrolysis

can produce a higher xylose of 2.89 g/L than 453xylitol fermentation. Fermented results

show that fermentation using enzymatic hydrolyzate gave higher xylitol yield (YP/S) and

specific growth rate (μ) than the fermentation using acid hydrolyzate.

Keywords: Fermentation, Hydrolysis, Xylitol, Xylose.


CHILDHOOD ACTIVITIES MEMORIES AMONGST HEALTHY ADULTS IN

THE MODEL OF INTERVENTION REMINISCENCE BASED SCREENING

Eva Berthy Tallutondok1*

Gd. FK-UPH Lt. 4. Jl. Boulevard Jen. Sudirman

(Samping RS Siloam) Lippo Karawaci, Tangerang, Banten

Faculty of Nursing, Universitas Pelita Harapan, Tangerang 15811,

Indonesia


ABSTRACT

Population ageing is a global public health concern, because some older people who are

a vulnerable people, might be have a normal mental status in the community or at a

nursing home. However, the population ageing needs promotive and preventive program

to maintain the quality of life, it is importance to encourage be an independent people in

the community. Therefore, exploring of childhood activities memories amongst healthy

adults help to develop a model of intervention reminiscence based screening in Indonesia.

Exploring of childhood activities memories amongst healthy adults is a part of activities

in the model intervention reminiscence based screening amongst healthy older. It is the

third of four strategies to optimize the cognitive function; namely screening, measuring

function cognitive, brain activities, and observation of reminiscence communication with

peer group. The purpose of this study was to identify how many kinds of childhood

activities that healthy adult is still remembering and able to speak up during survey. The

study was a descriptive quantitative study by survey with the semi-structure interview.

The participants (n=22) who involved in this study were selected by criteria such as

healthy adults aged 60 and over, passed screening on hearing function and verbal ability

and the cognitive function score 24 – 30 by the mini mental state examination, and

domicile at a nursing home. The data were collected once after knowing data primer,

passing on screening and having score 24-30. The data were explored by a semi-structure

interview during survey, it was asking about “Let you tell me kinds of childhood

activities that you are still remember.” All data note during the interview, then data

simply identified and wrote down the main themes that emerge to the document by using

decontextualization, recontextualization, categorization, and compilation. There were

found 33 kinds of childhood activities which fell into five categories consisting of games,

sports, music, spiritual activities, and hobbies. The five categories given effect to mediate

on prosocial behavior and memory during reminiscence communication with peer group.

This study warrants further for future strategy of developing a model intervention

reminiscence based screening in Indonesia government.

Key words: childhood activities memories, healthy adults, model intervention

reminiscence based screening.



NON-INVASIVE MONITORING OF STRESS IN FEMALES CRESTED

MACAQUES (Macaca nigra): COMPARISON OF GLUCOCORTICOID

LEVELS DURING CYCLING, PREGNANCY, AND LACTATION

Gholib Gholib1, Muhammad Agil2, Iman Supriatna2, Bambang Purwantara2,

Triva Murtina Lubis1, Mulyadi Adam1, Azhar1

1Laboratory of Physiology, Veterinary Medicine Faculty, Syiah Kuala University,

Banda Aceh, Jl Tgk Hasan Krueng Kalee No.4 Kopelman Darussalam, Banda Aceh

23111, Indonesia. 2Department of Clinic, Reproduction, and Pathology, Faculty of Veterinary Medicine,

Bogor Agricultural University, Bogor.

ABSTRACT

Reproduction is a period which energetic cost especially for female related to

physiological changes during cycling, pregnancy, and lactation. The aim of this study

was to compare the levels of glucocorticoid in females of crested macaques during

cycling, pregnancy, and lactation. Fecal samples were collected from 12 females of

crested macaques living in the Tangkoko-Batuangus Nature Reserve, North Sulawesi,

Indonesia. Fecal samples were assayed by an enzyme immunoassay technique for

measuring fecal glucocorticoid metabolites (fGCM). The results showed that female

reproductive status (cycling, pregnancy, and lactation) was significantly influence to the

levels of glucocorticoid (p<0.01). Levels of fGCM in pregnant females were significantly

higher compared to the levels of fGCM in cycling and lactation females (p<0.05).

Whereas, levels of fGCM between cycling females and lactation females were not

significantly different (p>0.05). Mean (±SEM) of the absolute levels of glucocorticoid in

cycling, pregnant, and lactation females were 388.19±60.59 ng/g, 814.20±139.12 ng/g,

and 403.13±39.34 ng/g, respectively. In conclusion, female reproductive status

influences the levels of fGCM.

Keywords: crested macaques, cycling, fGCM, lactation, pregnancy.


POTENTIAL OF WOOD-DEGRADING BASIDIOMYCETES Marasmiellus sp

AND Ganoderma lucidum IN XYLANASE ENZYME PRODUCTION AND ITS

ACTIVITY USING AGRO-INDUSTRY WASTE

Tri Yuliana1*, Efri Mardawati2, Souvia Rahimah1, SON Yudiastuti3

1 Department of Food Technology, Faculty of Agro-Industrial Technology, Padjadjaran

University, Bandung 45363, Indonesia 2Department of Agricultural Industry Technology, Faculty of Agro-Industrial

Technology, Universitas Padjadjaran, Bandung 45363, Indonesia 3 Department of Agricultural Science, Faculty of Agriculture, Universitas Padjadjaran,

Bandung 45363, Indonesia

Coresponding author e-mail: [email protected]

ABSTRACT

Nowadays, agro-industrial waste such as sunan hazelnut shell is abundant along with the

development of biodiesel production made from raw sunan hazelnut. The production of xylanase

from sunan hazelnut shell waste was carried out by solid state fermentation method using

Basidiomycetes Marasmiellus sp and Genoderma lucidum. Enzyme activity of xylanase was

tested by measuring the amount of reducing sugar liberated from the medium by reactants using

DNS method. The highest of enzyme activity resulted from fermentation using 4% of substrate

concentration either by Marasmiellus sp or Genoderma lucidum. Fermentation by Marasmiellus

resulted the highest xylanase enzyme activity as much as 190.5 U mL-1 within 48 hours.

Meanwhile, the highest enzyme activity of xylanase fermentation by Genoderma lucidum was

obtained at most 121.9 U mL-1 within 72 hours and it still showed a tendency to increase.

Keywords: Agro-industry waste, xylanase, Marasmiellus sp, Genoderma lucidum, Solid State

Fermentation.



THE COMPARATION INSULIN RECEPTOR AND INSULIN RESISTANCE

BETWEEN SLOW INTERVAL TRAINING AND MODERATE CONTINOUS

Yetty Machrina1, Ambrosius Purba2, Dharma Lindarto3

1Department of Physiology, Faculty of Medicine, Universitas Sumatera Utara, Medan

20155, Indonesia 2Department of Physiology, Faculty of Medicine, Universitas Padjajaran, Bandung,

45363, Indonesia 3Departement of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara,

Medan 20155, Indonesia


ABSTRACT

Insulin receptor sensitivity improvement was a management target of diabetes mellitus

type-2. Exercise was one of the best ways to increase insulin receptor and decrease

insulin resistance. The aim of this study was to compare insulin receptor and insulin

resistance in slow interval training and moderate continous in diabetes mellitus type-2

model rat. Experimental study was held by using diabetes mellitus type-2 model rat,

Wistar age 12 weeks, 150-180 gram on body weight. The objects were divided into three

groups, sedentary, moderate continous training and slow interval training. The

intervention for treatment groups was ran on the treadmill 3 times/week for 8 weeks.

Insulin receptor from m.gastrocnemius counted by using Imunohistochemystri method,

insulin resistance has been measured before and after exercise. The study found that

insulin receptor in treatment groups were significant difference between treatment groups

than sedentary (p=0,002). Insulin receptor in slow interval training was higher but not

statistically different compared with moderate continous training (p=0.222). Insulin

resistance in slow interval was lower than moderate continous training (p=0.000). Both

moderate continous training and slow interval training could increase insulin receptor on

skeletal muscle and improved insulin sensitivity. Slow interval training can be suggested

as exercise model for diabetes mellitus type-2. Insulin receptor, insulin resistance, slow

interval training, moderate continous training.

Keywords: Insulin receptor, insulin resistance, slow interval training, moderate

continous training.


SENSORY EVALUATION WITH DESCRIPTIVE METHOD ON ACEH

LOCAL RICE (Oryza Sativa L.) MUTANT M6 USING GAMMA-RAY

IRRADIATION

Rita Hayati1*, Efendi1 and Fitri Yunita1

1Agrotechnology Study Program, Faculty of Agriculture, Syiah Kuala University,

Banda Aceh 23111, Indonesia


ABSTRACT

Aceh is the richest province in Indonesia in the context of diversity with the local rice

varieties. Therefore, it requires conservation efforts within this issue. The weakness

parameters of local rice are long-lived and low production. One of the technologies that

are been used to obtain the characteristics of short-lived local rice and high production is

by using gamma-ray irradiation technology. The purpose of this research is to know the

quality of sensory evaluation with descriptive method on the local rice Aceh Mutant M6

by gamma-ray irradiation. The local rice Aceh Mutant M6 that has been used in this study

are I-CKU-6, UF1 B4-9-2017, O-SGP, O-10D, S-103, S-97, S-01 (conventional and

organic cultivation), O-39 e, O-10 d, O-57 e (organic cultivation), S-97, S-84 dan UFi-B

(conventional cultivation). The approach that has been used in this research is using

Completely Randomized Design (CRD) non factorial with three replicates. The result

showed that local rice with irradiated gamma-ray (M6) had a very significant effect on

the flavour, color, texture, shape, and overall acceptance of rice by conventional and

organic cultivation. The local rice O-SGP (5.82) is the local rice that has been received

by panelists, followed by local rice S-103 (5.75), O-10D (4.95) and S-97 (4.70), while

the aroma is favored by panelists is O-SGP (4.92). S-84 local rice which is grown

conventionally is preferred by panelists with a value of 9.85.

Keywords: Aceh local rice, gamma-ray irradiation, mutation, sensory evaluation.


LIME LEAVES ETHANOL-EXTRACT, CAJUPUT OIL, AND ITS

COMBINATION EFFECTS TO RICE WEEVIL MORTALITY

Nabiila Kaltsum Ulayya1*, Udi Tarwotjo1 and Rully Rahadian1

1Department of Biology, Faculty of Science and Mathematics, Diponegoro University,

Semarang 50275, Indonesia


ABSTRACT

The main storage pest of rice is Sitophilus oryzae (rice weevil). Combination of herbs

that potentially used natural insecticides is key lime (Citrus aurantifolia) leaves and

cajuput oil (Melaleuca cajuputi). The aim of this research is to compare the effect of

toxicity of lime leaves ethanol-extract, cajuput oil and its combination against rice weevil

mortality, and to analyze the chemical composition of lime leaves extract and cajuput oil.

The extraction of lime leaves based on ethanol-maceration method, then mixed with

cajuput oil. A bioassay, with varying concentrations of the lime-leaves extract, cajuput

oil, and the combination of both with the volume ratio 1:1, 2:1 and 1:2 were carried out

against rice weevils using filter paper; then the data analyzed by probit analysis to

determine the LC50 value. The results showed that the toxicity of lime leaves extract

(LC50 16,67%) was significantly different with cajuput oil (LC50 32,46%). Overall, the

toxicity of combination formula of lime leaves extract and cajuput oil with a volume ratio

2:1 as the most effective combination to rice weevil adults mortality with LC50 value was

10,55%. The chemical compound of lime leaves extract was limonene, α-terpineol,

linalool, dihydromyrcenol, isocineole, and 1,8-cineole. The chemical compound of

cajuput oil was α-pinene, 1,8-cineole, trans-β-ocimene, γ-terpinene, β-pinene,

terpinolene, camphene, α-terpineol, myrcene dan β-caryophyllene.

Keywords: cajuput oil, lime leaves extract, rice weevil.


TOXICITY SUB-CRONIC ETHANOLIC EXTRACT OF MALAKA

(PHYLLANTHUS EMBLICA) LEAVES ON LIVER FUNCTION OF MICE

(Mus musculus) BE REVIEWED FROM SERUM BILIRUBIN LEVEL

Nuzul Asmilia1,2, Yudha Fahrimal3, Mahdi Abrar4, Rinidar5

1Study Program DMAS, Syiah Kuala University, Darussalam, Banda Aceh 23111,

Indonesia 2Clinical Laboratory of Veterinary Medicine, Syiah Kuala University, Darussalam,

Banda Aceh 23111, Indonesia 3Parasitology Laboratory of Veterinary Medicine, Syiah Kuala University, Darussalam,

Banda Aceh 23111, Indonesia 4 Microbiology Laboratory of Veterinary Medicine, Syiah Kuala University,

Darussalam, Banda Aceh 23111, Indonesia 5Farmacology Laboratory of Veterinary Medicine, Syiah Kuala University,



ABSTRACT

The aim of this research was to investigate the subchronic toxicity of ethanolic extract of

malaka leaves (Phyllanthus emblica) on liver function by analyzing bilirubin level in

mice blood (Mus musculus). Sixteen male mice weighing between 25-30 grams were

used in this study. Ethanolic extract of malaka leaves was given orally once a day for 21

consecutive days. Mice were randomly divided into 4 groups of 4 mice each. Control

group (P0) was given distilled water; group P1, P2, and P3 were administered with

ethanolic extract of malaka leaves with the dose of 300 mg/kg bb, 600 mg/kg bb, and

1200 mg/kg bb, respectively. Blood sample was taken on day 21 after treatment to

measure mice bilirubin level. The results showed that blood bilirubin level of mice in P0,

P1, P2, and P3 were 1.4; 1.4; 1.4, and 1.4mg/dl respectively. In conclusion, the

administration of ethanolic extract of malaka leaves with repeated doses for 21 days does

not have negative effect on mice liver.

Keywords: ethanolic extract of malaka leaves, liver function, bilirubin direct.



STUDY OF FICUS LYRATA WARB FRUIT EXTRACT EFFECT ON

TOXICITY, PHYSICOCHEMICAL, AND MICROBIOLOGY PROPERTIES

OF CHICKEN CARCAS

Dwi Wahyudha Wira1*

1Faculty of Veterinary Medicine, Padjadjaran University, Bandung 45363, Indonesia


ABSTRACT

The use of plant extraction as natural and safe preservatives have been highly

recommended for the improvement of the sensory quality and microbiological of

food. In the present investigation, the dried fruit of Ficus lyrata Warb was subjected to

biopreservative to the chicken carcass. The aims of this study were to determine the

toxicity of the extraction with lethal dose (LD50) value and to study the application of the

extract as chicken carcass preservative. The result of acute toxicity analyze showed that

the extract of Ficus lyrataWarb fruit has not the LD50 below the concentration of 15000

mg/kg weight, that means the extraction was practically nontoxic. The application of

extract to chicken carcass had shown the pH of carcass in the range 5.51-5.98 and

decreased the temperature from 26 to 24oC. The extract of F. lyrata Warb fruit also

inhibited the bacterial growth until 2.4 x 106 CFU/g within the 12 hours of storage and

increased the tenderness of carcas to 0.6N.

Keywords: Antibacterial, chicken carcass, Ficus lyrata Warb, natural preservative.



THE PROFILE OF BACTERIAL URINARY TRACT INFECTION

AETIOLOGY ISOLATED FROM HOSPITALIZED PATIENTS IN DR.

ZAINOEL ABIDIN GENERAL HOSPITAL BANDA ACEH

Wildani Mahdani1,2*, Zinatul Hayati1,2, Ridhia Putri2, Teuku Fadrial Karmil3

1Department of Microbiology, Faculty of Medicine, University of Syiah Kuala, Darussalam,

Banda Aceh 23111, Indonesia 2Clinical Microbiology Laboratory, Dr. Zainoel Abidin General Hospital, Banda Aceh 23126,

Indonesia 3Department of Clinical Veterinary, Faculty of Veterinary Medicine, University of Syiah Kuala,



ABSTRACT

Urinary tract infections (UTI) caused by bacteria suffered by hospitalized patients is a

challenge that can affect patient's treatment and prognosis. The issue of antibiotic

resistance is also urgent to be considered in the management of these infections. This

study aims to obtain informations on the prevalence of bacterial pathogen that caused

urinary tract infection among the inpatients in dr. Zainoel Abidin General Hospital in

addition to determining the susceptibility pattern of bacteriae that were isolated from

urine specimens. Identification and antibiotic susceptibility testing were performed using

VITEK® 2 Compact semiautomatic system (bioMérieux, France). This study was carried

out in dr. Zainoel Abidin Hospital Banda Aceh, from September to November 2017. We

collected 307 urine samples. Bacterial growth were obtained in 118 samples and 93 of

those met the UTI diagnosis criteria. They derived from 43 (46.2%) female and 50

(53.8%) male patients with the age range 1 to 80 years old on average 50.63 (deviation

standard 21.15). UTI samples mostly came from internal ward 73 (78.5%) followed by

surgery ward 9 (9.7%) and intensive care unit 4 (4.3%). Most Gram negative isolates

were Escherichia coli 24 (25.8%), Klebsiella pneumoniae 14 (15%) and Acinetobacter

baumannii 9 (9.7%). Gram positive isolates took a small part dominated by

Staphylococcus haemoliticus 3 (3.2%). Gram negative isolates showed high

susceptibility to Tigecycline, Amikacin and Meropenem. While Gram positive isolates

showed high susceptibility to Vancomycin, Linezolid and Tigecycline. The commonly

used third-generation cephalosporins appear to be ineffective to be recommended as

empirical therapy for these patients.

Keywords: Urinary tract infection, hospitalized patient, antimicrobial susceptibility.



ASSOCIATION BETWEEN RAMADAN FASTING AND

GASTROESOFAGEAL REFLUX DISEASE CLINICAL SYMPTOMS IN ACEH

TAMIANG HOSPITAL

Anandita Putri1*

1Rumah Sakit Cut Mutia, Langsa, Provinsi Aceh, Indonesia


ABSTRACT

Gastroesophageal Reflux Disease (GERD) is a disorder that causes the stomach fluid to

experience reflux into the esophagus and make the symptoms occur. The validated

questionnaire for the diagnosis and response of GERD therapy is Gastroesophageal

Reflux Disease Questionnaire (Gerd-Q). GERD risk factors may change during Ramadan

fasting. Based on Mardiah et al, complaints of GERD were felt lighter during fasting

month (Ramadan) than non-fasting months. The purpose of this study was to determine

the association between Ramadan fasting and the clinical symptoms GERD

patients. This research is a longitudinal study with a total sampling. Research subjects

were grouped into two groups, i.e those who performed Ramadan fasting (n = 24) and

those who did not (n = 20). The evaluation was conducted between the two groups. Then

the Ramadan fasting group was also evaluated 14 days after they performed the fasting.

The evaluation was done by using the Indonesian version of GERD-Q questionnaire. In

the Ramadan fasting group, there was a statistically significant difference in the median

GERD-Q score (p <0.05) between before they fasted with a median score of 10 and then

14 days after fasting with a median score decreasing to 5. Meanwhile, when an analysis

was done to compare median GERD-Q score between Ramadan fasting group and non-

fasting group, there was also a significant difference (p <0.05). When breaking the fast

(ifthar), sphincter pressure (lower esophageal sphincter/LES) decreases and reflux occurs

symptoms. Type of nutrients that are consumed when breaking the fast should be food

with low fat content and in small portions with intervals. A study conducted by Iraki et

al, there was a decrease in mean gastric pH when fasting compared to when they did not

fast in patients who had performed Ramadan fasting more than 10 days. On subjects who

performed fasting during Ramadan, these subjects felt the GERD symptoms were ligther

during Ramadan than before the fasting month. In Ramadan, GERD complaints were felt

lighter by subjects who performed Ramadan fasting than subjects who did not perform

the fasting.

Keywords: Gastroesofageal Reflux Disease, GERD, Ramadan fasting.


CHEMICAL AND MICROBIOLOGICAL CHARACTERISTICS OF COCOA

BEANS FROM PIDIE DISTRICT, ACEH PROVINCE, INDONESIA

Martina Fitri Wahyuni1*, Dewi Yunita1, Yusriana Yusriana1, Yuliani Aisyah1




ABSTRACT

The aim of this research was to examine the chemical and microbiological characteristics

of cacao beans which are used as a raw material of a small chocolate factory in Pidie Jaya

District, Aceh Province, Indonesia. The information will be used to improve the sensory

quality of the cacao beans. Samples were collected from a local farmer in Padang Tiji

Sub-District, Pidie District, Aceh Province, Indonesia starting from Day 0 to Day 5

fermentation, after drying, and after roasting in triplicate. Samples were then analysed

for water content, pH, and total cell count of lactic acid bacteria, acetic acid bacteria, and

yeast and mould. The results showed that the water content slightly decrease during

fermentation from 14.23% to 11.73% and continued to decline dramatically to only 0.3%

after roasting. Also, the pH declined from 4.91 at Day 0 to 3.93 at Day 3 fermentation

suggesting the growth of both groups of bacteria. However, the pH increased at Day 4

(4.15) and 5 (4.41). It was expected because the mould has started to grow. The analysis

of flavour compounds of the cocoa beans is under investigation.

Keywords: cacao beans, Aceh cacao, BAL, BAA, yeast and mould.


TREATMENT OF INTRODUCTION OF LEAF FERMENTATION AND

DISTILATION ON EUCALYPTUS OIL RENDEMEN

Novi Mailidarni1, Anshar Patria1, Yuliani Aisyah1




ABSTRACT

The suplay of eucalyptus oil needed in Indonesia is also increasing, while the supply of

eucalyptus oil is still very minimal. Therefore in this study an attempt was made to

examine the effect of the quality and yield of eucalyptus oil resulting from the

preliminary treatment of leaves which can degrade the cell wall components of leaf tissue

during the fermentation process so that more essential oil is obtained during the

distillation process. Variables used preliminary treatment of fermented leaves for 2 days,

4 days, and 6 days respectively, with distillation time of 4 hours, 5 hours and 6 hours.

While the parameters analyzed were rendement, refractive index, weight type test,

glucose standard and leaf microscope analysis and organoleptic test (aroma and color).

The research data was processed using Randomized Complete Design (RAL) Factorial

with 3 replications, data analysis with ANOVA and Honest Significant Difference Test

(BNJ). Level of glucose of eucalyptus leaves on fermentation of leaves 2 days (F1) 46%

while in treatment of fermentation of leaf 6 days (F3) glucose level decreased to 22%.

The best treatment in this research is on (F3P3) with yield 0.94. refractive index 1.48 and

type weight 0.9430 (meet SNI standard), organoleptic color 3.67 (likes) and organoleptic

aroma 4.02 (likes).

Keywords: distillation, eucalyptus oil, leaf fermentasion.



EFFECTS OF TYPE AND CONCENTRATION STABILIZERS ON THE

CHARACTERISTICS OF NUTMEG OIL NANOEMULSIONS PREPARED BY

HIGH PRESSURE HOMOGENIZATION

Yuliani Aisyah1, Sri Haryani1, Ayu Simah Bengi1




ABSTRACT

Nutmeg oil is one of the essential oils that have ability as an antibacterial so it potentially

uses to inhibit the growth of undesirable microbes in food. However, the essential oil that

have low solubility in water, high volatile content, and strong aroma properties is difficult

to apply in to foodstuffs. Therefore, the oil-in-water nanoemulsion system was used in

this research. Gelatin, lecithin and tween 80 with 10%, 20%, 30% concentrations have

been examined for the preparation of nutmeg oil nanoemulsions. The physicochemical

properties and stability of nutmeg oil nanoemulsion were analyzed on viscosity,

creaming index, emulsifying activity, droplet size, and polydispersity index. The results

showed that the type and concentration stabilizer had a significant effect on viscosity,

creaming index, droplet size and polydispersity index (P≤0,01). The nanoemulsions

stabilized with tween 80 had the best stability because the creaming index value was 0%,

the emulsifying activity value was 100%, the droplet size was small (79 nm) and the

polydispersity index was low (0.10) compared to the nanoemulsions stabilized with

gelatin and lecithin. In brief, Tween 80 is strongly recommended to be used for stabilizing

nutmeg oil nanoemulsions.

Keywords: nutmeg oil, nanoemulsion, stabilizer, stability.

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