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The International Committee on Food Microbiology and Hygiene of the International Union of Microbiological Societies Athens, Greece· 13-14 May 2016 www.icfmh.org Since 1953 a non-profit academic body dedicated to safer and healthier food from the international perspective Prof. Dr. Luca Cocolin Next Generation MRA– Integration of Omics Data into Risk Assessment

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The International Committee on Food Microbiology and Hygiene of the International Union of Microbiological Societies

Athens, Greece· 13-14 May 2016

www.icfmh.org

Since 1953 a non-profit academic body dedicated to safer and healthier food from the international perspective

Prof. Dr. Luca Cocolin

Next Generation MRA– Integration of Omics Data into Risk Assessment

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Mission

• To contribute to food safety internationally, by means of conferences (e.g. FOOD MICRO), workshops, support of international bodies in food safety issues, publications (e.g. the IJFM), and by support and initiation of education and training in food microbiology.

• The ICFMH particularly focuses on the food safety situation in developing countries

Information on the ICFMH

• Founded in 1953, the ICFMH officially represents the IUMS in all issues related to food microbiology.

• The ICFMH has observer and/or advisory status in activities of FAO and WHO, ISO working groups related to the detection and enumeration of microorganisms in food commodities, etc.

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

President: Prof. Dr. Wilhelm Holzapfel / Germany

Honorary President: Prof. Dr. Mogens Jakobsen / Denmark

Vice-President: Prof. Dr. Larry R. Beuchat / USA

Secretary: Dr. Sara Bover i Cid / Spain

Treasurer: Dr. Janet E.L. Corry / UK

Co-opted Members:

Prof. Dr. Luca Cocolin / Italy

Prof. Dr. Weihuan Fang / China

Prof. Dr. Bernadette Franco / Brasil

Dr. Andreja Rajkovic/ Belgium

Prof. Dr. Peter Raspor / Slovenia

Dr. Vasilis Valdramidis/ Malta

Executive Board Members

Information on the ICFMH

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

National Delegates

Further information on homepage: http://www.icfmh.org/

Information on the ICFMH

About 50 countries represented (contacts being updated)

Role:

• The bond between the ICFMH Executive Board and microbiological societies, scientists, and research groups in National Delegates’ countries.

• Disseminators of the ICFMH activities (Food Micro Conferences, Mobility Grants, workshops...) among food microbiologists and scientists of your country.

• National Delegate expertise in different areas of food microbiology is

very valuable in relation to their possible contribution to the ICFMH mission.

• The ICFMH will always welcome the National Delegates’ suggestions

and feedback by e-mailing the ICFMH Secretariat.

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Contact

President: Professor Dr. Wilhelm Holzapfel Handong Global University, Pohang, South Korea E-mail: [email protected] cc. to: [email protected]

Secretary: Dr. Sara Bover-Cid IRTA (Institute for Food and Agriculture Research and Technology) Finca Camps i Armet s/n, E-17121 Monells, Spain E-mail: [email protected]

Information on the ICFMH

Homepage

www.icfmh.org

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

International ICFMH Conferences - FOOD MICRO

ICFMH Activities

25th International ICFMH conference, FOOD MICRO 2016 19-22 July 2016 Dublin, Ireland

www.foodmicro2016.com

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

International Journal of Food Microbiology

The “flagship” of the ICFMH. Editor-in-Chief: Dr. Luca Cocolin (from Jan 2008) For more information, visit: www.elsevier.com/locate/ijfoodmicro

ICFMH Activities

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SNIP 2014

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1.334

CITATION IMPACT

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Working Party on Quality Assurance and Quality Monitoring of Culture Media (WPCM)

Handbook of Culture Media for Food Microbiology 3rd Edition, Published by the Royal Society of Chemistry (Cambridge, GB, 2012) Editors: J E L Corry, G D W Curtis and R M Baird. ISBN 13: 9781847559166 ISBN 10: 1847559166

Janet Corry +info:

ICFMH Activities

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Working Party on Advanced Education in Food Microbiology (WPAEFM)

The WPAEFM, within ICFMH, acts as a platform for structuring curricula and providing guidance for relevant authorities, national bodies and academicians focused on food microbiology and hygiene. The 2nd WPAEF symposium: Food Microbiology Education in Practice, will take place during the Food Micro 2016 in Dublin.

ICFMH Activities

Education curricula in food microbiology differ widely among countries due to a lack of consensus within scientific and professional circles.

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Workshops

ICFMH Activities

“Food Safety in Africa” University of Stellenbosch, SOUTH AFRICA (2003 & 2007) Accra, GHANA (2014)

“Traditional fermented foods” BURKINA FASO (2009) Copenhagen, DENMARK (2010) Nantes, FRANCE (2014) Next: Dublin, IRELAND (2016)

IUMS Outreach Program. Food Safety Bali, INDONESIA (2011)

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Workshops

ICFMH Activities

Athens, Greece· 13-14 May 2016

ILSI – IAFP - ICFMH Next Generation MRA– Integration of Omics Data into Risk Assessment

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Sponsorships

Travel grants Grants to support scientists from developing countries to attend and participate in FOOD MICRO conferences

ICFMH Activities

Mobility grants Grants to assist developing scientists in pursuing research at a host laboratory (max. 3 months)

Call for applications are open regularly each year Deadline 31st March

Further information on homepage: http://www.icfmh.org/

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Awards

Developing Scientist Poster and Oral comunication Competition at FOODMICRO

1st award (500 €) 2nd award (300 €) 3rd award (100 €)

ICFMH Activities

ICFMH Best Poster Award at scientific events other than FoodMicro The topic of the competing poster should be food microbiology and hygiene 1st award (500 €)

Satellite Event of the

IAFP European Symposium on Food Safety 2016

ILSI Europe, IAFP & ICFMH Workshop

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

There are newly established tools that allow us to change our approaches to risk assessment concerning food pathogens and process ecology.

During this workshop we will take on this challenge with us and bring together experts in the field of risk assessment to jointly generate indications and guidance on Next Generation MRA.

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Background to the Current Workshop

The scientific questions to be discussed are the use of Whole Genome Sequencing in outbreak detection and epidemiology, the use of metagenomics to determine product and process ecology, the use of -omics in exposure assessment and hazard characterisation, and to outline the impact of these on MRA.

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Objectives of the Current workshop

The Use of Whole Genome Sequencing in

Outbreak Detection and Epidemiology

Dr Paul Cook, Food Standards Agency (FSA),

United Kingdom

Head of the Microbiological Risk Assessment

Branch in the Science, Evidence and Research

Division of the Food Standards Agency (FSA) in

the UK.

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Speakers

The Use of Metagenomics to Determine

Product and Process Ecology

Dr Kalliopi Rantsiou, University of Turin, Italy

Assistant Professor at the Department of

Agricultural, Forest and Food Sciences,

University of Turin, Italy.

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Speakers

The Use of Omics in Exposure

Assessment and Hazard Characterisation

Dr Eelco Franz, Dutch National Institute for Public

Health and the Environment (RIVM), The

Netherlands

Research leader for genomic epidemiology at the

Dutch National Institute for Public Health and the

Environment (RIVM), within the Centre for

Infectious Disease Control.

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Speakers

Breakout Group 1: Epidemiology

• What are the strengths and weaknesses of using WGS in routine

surveillance?;

• What are the strengths and weaknesses of using WGS in outbreak

detection and investigation?;

• What are the strengths and weaknesses of using WGS in attribution

(e.g. to source, reservoir, location, etc.)?;

• How can WGS be used to improve our understanding of

transmission routes?;

• How can genome sequencing and other data be used to inform

hazard identification?;

• What future developments are needed to maximise the potential

of WGS in epidemiology and risk assessment?

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Breakout groups

BG 1. Epidemiology

Friday 13 May 15.45-17.15: Room MC3

Saturday 14 May 8.30-10.00: Ballroom A

Paul Cook Food Standards Agency (FSA)

Kalliopi Rantsiou University of Turin

Alejandro Amezquita Unilever

Diána Bánáti ILSI Europe

Sophia Kathariou North Carolina State University

Katia Rouzeau Nestlé

Manuel Saint-Cyr

French National Institute for

Agricultural Research (INRA)

Panagiotis Skandamis Agricultural University of Athens

Anett Winkler Mondelēz Europe

Breakout Group 2: Metagenomics

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Breakout groups

• Metagenetics, metagenomics and metatranscriptomics: how to get the

best out of their application for microbiological risk assessment?;

• From in vitro to in situ and in vivo experimental conditions: procedural

barriers and methodological standardisation;

• From presence to behavior: is it necessary to switch from DNA to RNA

in microbiological risk assessment?;

• Behavioral biodiversity: how to address it in microbiological risk

assessment?;

• Linking presence of genes to their biological context (i.e. organisms);

• How will this impact tradition microbiology programs in industry?

BG 2. Metagenomics

Friday 13 May 15.45-17.15: Room MC3.2

Saturday 14 May 8.30-10.00: Ballroom B

Luca Cocolin University of Turin

Eelco Franz

Dutch Institute for Public Health

and the Environment (RIVM)

Francois Bourdichon Danone

Alessandra De Cesare University of Bologna

Agapi Doulgeraki Agricultural University of Athens

Bala Jagadeesan Nestlé

Balkumar Marthi Unilever

Marios Mataragas Agricultural University of Athens

Marie-France Pilet

French National Institute for

Agricultural Research (INRA)

Jos van der Vossen

Netherlands Organisation for Applied

Scientific Research (TNO)

Breakout Group 3: Exposure

Assessment

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Breakout groups

• How -omics could help in building accurate exposure assessment

model, taking into account variability of microbial stress response,

variability due to:

• strain and cell differences;

• environmental “history” differences?;

• Knowing that biomarkers are defined so far based on transcriptomics

analyses, how to get further, i.e. towards integration of proteomics and

metabolomics results (‘food -omics’ approach)?;

• WGS and exposure assessment: more than markers for persistence?

BG 3. Exposure Assessment

Friday 13 May 15.45-17.15: Room MC3.3

Saturday 14 May 8.30-10.00: Ballroom C

Jeanne-Marie Membré

French National Institute for

Agricultural Research (INRA)

Heidy den Besten Wageningen University

Jozsef Baranyi Institute of Food Research (IFR)

Sara Bover-Cid

Institute for Food and Agriculture

Research and Technology (IRTA)

Nathália Buss Da Silva

Federal University of Santa

Catarina (UFCSC)

Stéphane Dagnas Bel Group

Mariem Ellouze Nestlé

Sandrine Guillou

Nantes Atlantic College of

Veterinary Medicine (Oniris)

George Nychas Agricultural University of Athens

Cian O'Mahony Creme Global

Breakout group 4: Hazard

Characterisation

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Breakout groups

• How can factors like gene presence/absence, SNPs, and multiple

copies, be related to virulence and the dose response relation?;

• How to take into account the response of the host immune system

(host susceptibility) in hazard characterisation?;

• How can transcriptomics be relevant for virulence and the dose

response relation?;

• How can links between NGS epidemiological data and exposure

assessment data best be used to inform hazard characterisation?;

• How can -omics data and NGS be further used in hazard

characterisation?;

• How can we relate the results of the above to quantify the dose-

response relation?

BG 4. Hazard Characterisation

Friday 13 May 15.45-17.15: Room MC3.3

Saturday 14 May 8.30-10.00: Ballroom D

Marcel Zwietering Wageningen University

Nabila Haddad

French National Institute for

Agricultural Research (INRA)

Gerardo Manfreda University of Bologna

Aline Metris Institute of Food Research (IFR)

Luís Nero Funarbe

Patrick Njage

National Food Institute, Denmark

Technical University

Annemarie Pielaat

Dutch Institute for Public Health and

the Environment (RIVM)

Marion Wells-Bennik NIZO Food Research

Trevor Phister PepsiCo International

Chrysoula Tassou

Hellenic Agricultural Organization –

DEMETER

•The workshop discussions will be captured in peer-reviewed

publications to be submitted to International Journal of

Food Microbiology

•All participants are welcome to actively contribute to

writing these publications

•Participants only joining the workshop discussions will be

mentioned in the acknowledgements section (unless

requested not to be)

•Please inform the Breakout group Chair and/or

Rapporteur if you would like to be involved in the follow-up

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Follow up

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

A previous successful story!

-Wolfheze, the Netherlands June 9-12, 2008, “Future Challenges to Microbial Food Safety”

- International Journal of Food Microbiology

Volume 139: S1-S94 (2010), 8 papers

- Food-borne diseases - The challenges of 20years ago

still persist while new ones continue to emerge : cited

279 times

- Future challenges to microbial food safety :

cited 67 times

Friday 13 May

19.00-21.00 Dinner Thissio View Apostolou Pavlou 25 GR – 118 51 Athens We will gather at the entrance of the Megaron Athens International Conference Centre at 19.00 (19.30 at the restaurant)

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Social programme

Saturday 14 May 8.30-12.00

and 12.00-13.00 Lunch Crowne Plaza Athens - City Centre Michalacopoulou Street 50 GR – 115 28 Athens

The International Committee on Food Microbiology and Hygiene (ICFMH)

of the International Union of Microbiological Societies (IUMS)

Social programme

The International Committee on Food Microbiology and Hygiene of the International Union of Microbiological Societies

[email protected]

www.icfmh.org

Since 1953 a non-profit academic body dedicated to safer and healthier food from the international perspective

For further information: