principals of genetics (zoo-352) department of zoology, 1435-1436 h

9
Principals of Genetics (Zoo-352) Department of Zoology, 1435- 1436 H

Upload: rodney-gilbert

Post on 22-Dec-2015

213 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: Principals of Genetics (Zoo-352) Department of Zoology, 1435-1436 H

Principals of Genetics (Zoo-352)Principals of Genetics (Zoo-352)

Department of Zoology, 1435-1436 H

Page 2: Principals of Genetics (Zoo-352) Department of Zoology, 1435-1436 H

Dr. Mikhlid Hamed Almutairi

Associate Professor

Medical Molecular genetics

Department of Zoology , College of ScienceKing Saud University P.O. Box 2455, Riyadh 11451 Saudi Arabia

Office number: 67أب , Ground floor

Emails: [email protected]

[email protected]

المطيري: حامد بن مخلد الدكتور

مساعد أستاذ

الطبية الجزيئية الوراثة

الملك جامعة العلوم، كلية الحيوان، علم قسمسعود

رقم البريد الرمز 2455صندوق الرياض، ،11451البريدي

السعودية العربية المملكة

: أب المكتب األرضي 67رقم الدور ، : االلكتروني [email protected]البريد

[email protected]

Page 3: Principals of Genetics (Zoo-352) Department of Zoology, 1435-1436 H

Learning objectives:To describe the two types of cell division.To compare between mitosis and meiosis.To find the similarity and differences between each

phase of mitosis by watching animation.To draw the cell chromosomes during metaphase of

mitosis.

Page 4: Principals of Genetics (Zoo-352) Department of Zoology, 1435-1436 H

Lectures

Dates Syllabus view

1 12/4/1436 Genetics overview2 19/4/1436 Chromosomes3 26/4/1436 The cell cycle and its checkpoint4 3/5/1436 Mitosis5 10/5/1436 Meiosis6 17/5/1436 Errors in meiosis7 24/5/1436 Exam 18 2/6/1436 Half term break holidays9 9/6/1436 Mendelian genetics10 16/6/1436 The law of segregation 11 23/6/1436 Testing the law of segregation12 30/6/1436 Law of independent assortment13 7/7/1436 Testing the law of independent

assortment14 14/7/1436 Genetics of the human blood

group, 15 21/7/1436 Exam 2

Time table for weekly planning for principles of genetics

Page 5: Principals of Genetics (Zoo-352) Department of Zoology, 1435-1436 H

Assessment

Lecture2 lecture exams (30%)Final exam (40%)70% of total grade

Laboratory30% of total grade

Page 6: Principals of Genetics (Zoo-352) Department of Zoology, 1435-1436 H

Genetics

Genetics is the study of genes, heredity, and genetic variation in living organisms.A gene is the molecular unit of heredity of a

living organism. A gene is a portion (or sequence) of DNA that

codes for a known cellular function (another definition)

Heredity is the passing of phenotypic traits from parents to their offspring, either through asexual reproduction or sexual reproduction.

Genetic variation, variation in alleles of genes, occurs between individuals or between populations.

Page 7: Principals of Genetics (Zoo-352) Department of Zoology, 1435-1436 H

Branches of GeneticsClassical Genetics: It is the oldest

discipline in the field of genetics, going back to the experiments of Gregor Mendel. The study of the transmission of genotype from parent to offspring.

Human genetics: is the study of heredity and variation in the humans.

Cytogenetics: is the study of chromosomes and chromosome abnormalities

Population genetics: The genetics of the different populations of animal and plant species.

Molecular genetics: is the study of the structure and function of genes at a molecular level.

Page 8: Principals of Genetics (Zoo-352) Department of Zoology, 1435-1436 H

Differences between Prokaryotic and Eukaryotic cells  Prokaryotic cells Eukaryotic cells

Taxonomic groups Bacteria, Cyanobacteria  all protists, fungi, plants, animals

Size Usually <5 µm Usually >5 µm Nucleus No true nucleus, no

nuclear membraneTrue nucleus, nuclear membrane

Genetic material One circular molecule of DNA, little protein

Linear DNA molecules complexed with histones

Mitosis and Meiosis

Absent present Eukaryotic cells contain many different organelles that

perform specific functions. Such as, nuclei, mitochondria, chloroplasts contain genomes.

The eukaryotic cell possesses some structures that are critical for mitosis and meiosis: centrosomes and microtubules/spindle fibers.

Page 9: Principals of Genetics (Zoo-352) Department of Zoology, 1435-1436 H

Classical Genetics: It is the oldest discipline in the field of genetics, going back to the experiments of Gregor Mendel. The study of the transmission of genotype from parent to offspring.

Human genetics: is the study of heredity and variation in the humans.