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WHO 2 nd Global Forum Medical Devices | Prevention & Early Diagnosis of NDD Prevention and Early Diagnosis of Alzheimer Disease (AD) The Role of Physical Activity and ICT Do ICT-based tools help to prevent AD? Dr. Rainer Wieching Information Systems & New Media University Siegen, Germany

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Page 1: Prevention and Early Diagnosis of Alzheimer …...- cognitive training, life-style - social involvement and QoL - food & medication Study Results: • Finish Study: n=20.000 (1971-2009)

WHO 2nd Global Forum Medical Devices | Prevention & Early Diagnosis of NDD

Prevention and Early Diagnosis of Alzheimer Disease (AD) The Role of Physical Activity and ICT Do ICT-based tools help to prevent AD? Dr. Rainer Wieching Information Systems & New Media University Siegen, Germany

Page 2: Prevention and Early Diagnosis of Alzheimer …...- cognitive training, life-style - social involvement and QoL - food & medication Study Results: • Finish Study: n=20.000 (1971-2009)

WHO 2nd Global Forum Medical Devices | Prevention & Early Diagnosis of NDD

Prevention of AD - The role of Physical Activity à There is huge evidence that physical activity (PA) is closely linked to the prevention of Alzheimers disease… Annals of Internal Medicine 2013, Med Sci Sports Exerc. 2012, Stroke 2012 à More than 35.000 patients in randomized controlled trials in different countries worldwide (Europe and North America) evidenced that physical activity is the most preventive measure for AD as compared to others like… - cognitive training, life-style - social involvement and QoL - food & medication

Study Results: •  Finish Study: n=20.000 (1971-2009)

=> 35% reduction of the risk of later life AD due to preventive physical activity

•  US Study: n=15.000 (1970-2001) => 50% reduction of the risk of later life AD due to preventive physical activity

Page 3: Prevention and Early Diagnosis of Alzheimer …...- cognitive training, life-style - social involvement and QoL - food & medication Study Results: • Finish Study: n=20.000 (1971-2009)

WHO 2nd Global Forum Medical Devices | Prevention & Early Diagnosis of NDD

Prevention of AD - The role of ICT Tools

à Modern ICT (e.g, smartphone, iTV or tablets) can help to inform, promote, and assess measures of PA as related to prevention and early detection of AD… à Gamification, virtual reality, sensors and ubicomp provide potential measures for effective prevention, early diagnosis, and guided intervention à There is a need that the use of such systems fit ideally into the daily practices of the end-users…

Examples… • Fall Prevention & Risk Prediction • Neurodegenerative Diseases

• Physical activity prevents the progression of AD by 39%… (LADIS study, n=90, Texas,US)

Page 4: Prevention and Early Diagnosis of Alzheimer …...- cognitive training, life-style - social involvement and QoL - food & medication Study Results: • Finish Study: n=20.000 (1971-2009)

WHO 2nd Global Forum Medical Devices | Prevention & Early Diagnosis of NDD

Prevention of AD – First Conclusions

à Further Evidence, e.g. in terms of RCTs and Living Labs is needed… à Evaluation of End-user and Stakeholder Needs & Expertise, Re-Design, Exploitation and later Clinical Testing … - Extended End-user Settings - Product & Market Aspects - New Technologies - Ethics & Laws

Examples of potential Settings & Activities… • Living Lab with more qualitative R&D • Wellbeing Interpersonal Spaces

Page 5: Prevention and Early Diagnosis of Alzheimer …...- cognitive training, life-style - social involvement and QoL - food & medication Study Results: • Finish Study: n=20.000 (1971-2009)

WHO 2nd Global Forum Medical Devices | Prevention & Early Diagnosis of NDD

Living Labs – Basic Concept

•  Real  Life  Experimental  Environment    •  Evolu3onary  /  Coopera3ve  Process  •  Par3cipatory  Design  

•  Living  Lab  •  Explora3on  •  Co-­‐Crea3on  •  Experimen3ng  •  Evalua3on  

Page 6: Prevention and Early Diagnosis of Alzheimer …...- cognitive training, life-style - social involvement and QoL - food & medication Study Results: • Finish Study: n=20.000 (1971-2009)

WHO 2nd Global Forum Medical Devices | Prevention & Early Diagnosis of NDD

Living Labs – References & Ideas

à Adoption by users in the earlier stages of research and development (Schaffers et al. 2011, Almirall & Waregam 2008) à Experimental environment: real life contexts in which end-users are actively involved in all lifecycles (Schumacher & Feurstein 2007) à User centred open innovation eco-system: stimulate innovation (Pallot 2009, Intille et al. 2005)

Page 7: Prevention and Early Diagnosis of Alzheimer …...- cognitive training, life-style - social involvement and QoL - food & medication Study Results: • Finish Study: n=20.000 (1971-2009)

WHO 2nd Global Forum Medical Devices | Prevention & Early Diagnosis of NDD

Inclusive Ageing Projects - Uni Siegen

1) FoSIBLE – Fostering Social Interaction for a Better Life of the Elderly (AAL-JP 2010 - 2013) 2) TOPIC – The Online Platform for Informal Caregivers (AAL-JP 2013 - 2016) 3) iStoppFalls – ICT-based System for Prevention and Prediction of Falls (EU FP7 2011-2014) 4) SehrMobil100 – Support of Seniors‘ Mobility in Daily Life (Ger.Min. of Education & Technology 2012-2015) 5) Alzheimer Monitoring (German Ministry of Economics 2009-2011) Example iStoppFalls…

Page 8: Prevention and Early Diagnosis of Alzheimer …...- cognitive training, life-style - social involvement and QoL - food & medication Study Results: • Finish Study: n=20.000 (1971-2009)

Project  Overview  

ICT for Ageing and Wellbeing ICT-2011-7.5.4.b

Page 9: Prevention and Early Diagnosis of Alzheimer …...- cognitive training, life-style - social involvement and QoL - food & medication Study Results: • Finish Study: n=20.000 (1971-2009)

Objec3ves  &  Impacts  Objectives

Impacts

End-User Setting

Page 10: Prevention and Early Diagnosis of Alzheimer …...- cognitive training, life-style - social involvement and QoL - food & medication Study Results: • Finish Study: n=20.000 (1971-2009)

iStoppFalls  System  Layout  

Page 11: Prevention and Early Diagnosis of Alzheimer …...- cognitive training, life-style - social involvement and QoL - food & medication Study Results: • Finish Study: n=20.000 (1971-2009)

iStoppFalls  RCT  &  Living  Lab  

Page 12: Prevention and Early Diagnosis of Alzheimer …...- cognitive training, life-style - social involvement and QoL - food & medication Study Results: • Finish Study: n=20.000 (1971-2009)

WHO 2nd Global Forum Medical Devices | Prevention & Early Diagnosis of NDD

Real Life Contexts

Living Labs

Health Care

Participat. Design

ICT-based Systems End User Appropriation

Physical Activity

Institute for ICT & New Media, University Siegen

Thank You…