prevalence of antisocial personality disorder in three groups of
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Longer Term Outcomes of Longer Term Outcomes of Two Universal, FirstTwo Universal, First--Grade Grade
Preventive Intervention Trials Preventive Intervention Trials NicholasNicholas IalongoIalongo, ,
Lisa Ulmer, Sheppard Lisa Ulmer, Sheppard KellamKellam, & , & C. Hendricks BrownC. Hendricks Brown
Prevention Intervention Research Center Prevention Intervention Research Center Johns Hopkins Bloomberg School of Johns Hopkins Bloomberg School of
Public HealthPublic Health
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Major Contributors to the Development of PIRC Interventions:
Mary Alice Bond, M.A.Mary Alice Bond, M.A.Joyce Epstein, Ph.D.Joyce Epstein, Ph.D.Becky Becky FetrowFetrow, M.A., M.A.Elizabeth Ramsey, Ph.D.Elizabeth Ramsey, Ph.D.Ruth Handel, Ph.D.Ruth Handel, Ph.D.Nancy Nancy KarweitKarweit, , Ph.DPh.DIrving Sigel, Ph.D.Irving Sigel, Ph.D.Grover Whitehurst, Ph.D.Grover Whitehurst, Ph.D.Carolyn WebsterCarolyn Webster--Stratton, Ph.D.Stratton, Ph.D.
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Juanita Lewis, Director, Office of Superintendent (CoJuanita Lewis, Director, Office of Superintendent (Co--Chair)Chair)Sheppard Sheppard KellamKellam, Director, Prevention Research Center (Co, Director, Prevention Research Center (Co--Chair)Chair)Elva J. Edward, Community Relations and Crisis ResponseElva J. Edward, Community Relations and Crisis ResponseLouise Fink, Coordinator, Special Pupil ServicesLouise Fink, Coordinator, Special Pupil ServicesCarla Ford, Interim Coordinator, Office of Early Learning YearsCarla Ford, Interim Coordinator, Office of Early Learning YearsClaudia Brown, Principal, Claudia Brown, Principal, BrehmsBrehms Lane Elementary SchoolLane Elementary SchoolLinda Linda ChinniaChinnia, Principal, Liberty Elementary School, Principal, Liberty Elementary SchoolJanet Cooper, Principal, Grove Park Elementary SchoolJanet Cooper, Principal, Grove Park Elementary SchoolCharlene CooperCharlene Cooper--Boston, Principal, Boston, Principal, BeechfieldBeechfield Elementary SchoolElementary SchoolElaine Davis, Principal, Hilton Elementary SchoolElaine Davis, Principal, Hilton Elementary SchoolLillian Jones, Principal, Callaway Elementary SchoolLillian Jones, Principal, Callaway Elementary SchoolBarbara Lee, Principal, Cross Country Elementary SchoolBarbara Lee, Principal, Cross Country Elementary SchoolAngela Peck, Principal, Angela Peck, Principal, YorkwoodYorkwood Elementary SchoolElementary SchoolShirley Shirley ZongkerZongker, Principal, , Principal, FarringFarring Elementary SchoolElementary School
Schools Committee: Classroom and Family Schools Committee: Classroom and Family Prevention TrialsPrevention Trials
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Intervention Types:Intervention Types:
UniversalUniversalSelectedSelectedIndicatedIndicatedTreatment / ServicesTreatment / Services
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JHU PIRC Interventions JHU PIRC Interventions Integrate 4 Perspectives:Integrate 4 Perspectives:
Public HealthPublic HealthEpidemiologyEpidemiologyLife Course DevelopmentLife Course DevelopmentSociologySociology
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Preventive Intervention Preventive Intervention Trials Serve a Dual Purpose:Trials Serve a Dual Purpose:
Test for intervention efficacy / Test for intervention efficacy / effectivenesseffectiveness
Test developmental theoryTest developmental theory
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Immediate objectives of Immediate objectives of the interventions:the interventions:
Promote first gradersPromote first graders’’::Academic achievementAcademic achievementSelfSelf--esteem and psychological wellesteem and psychological well--beingbeing
Reduce first gradersReduce first graders’’::Attention problemsAttention problemsAggressive and shy behaviorsAggressive and shy behaviors
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LongLong--term objectives of term objectives of the interventions:the interventions:
Promote:Promote:Educational, social, and occupational Educational, social, and occupational successsuccess
Prevent: Prevent: Antisocial behaviorAntisocial behaviorSubstance abuseSubstance abuseDepressionDepression
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Two firstTwo first--grade grade interventionsinterventions
FamilyFamily--School Partnership (FSP) Intervention School Partnership (FSP) Intervention targeting:targeting:
ParentParent--school communicationschool communicationParent Parent ““teachingteaching”” and discipline practicesand discipline practices
ClassroomClassroom--Centered (CC) Intervention Centered (CC) Intervention targeting:targeting:
Teacher classroom behavior management practicesTeacher classroom behavior management practicesTeacher instructional practicesTeacher instructional practices
Both delivered over course of firstBoth delivered over course of first--grade yeargrade year
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FamilyFamily--School Partnership: School Partnership: Parent Components / ToolsParent Components / Tools
Parent workshops (led by teacher and school Parent workshops (led by teacher and school mental health professional) aimed at:mental health professional) aimed at:
Establishing effective parentEstablishing effective parent--school partnershipsschool partnershipsStrategies to enhance their childStrategies to enhance their child’’s learnings learningEffective ways to discipline their childEffective ways to discipline their child
Learning tools available to parents:Learning tools available to parents:Parent lending libraryParent lending libraryA A ““Fun MathFun Math”” kitkitVoice mail system to communicate with teachersVoice mail system to communicate with teachers
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FamilyFamily--School Partnership: School Partnership: Teacher Components / ToolsTeacher Components / Tools
InIn--service training for teachers to assist them service training for teachers to assist them in:in:
Creating an environment that invites parent Creating an environment that invites parent involvementinvolvementCommunicating more appropriately with culturally Communicating more appropriately with culturally diverse familiesdiverse familiesIdentifying classroom factors and teaching practices Identifying classroom factors and teaching practices that hinder or promote parent involvementthat hinder or promote parent involvementPlanning and executing a successful parentPlanning and executing a successful parent--teacher teacher conferenceconference
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ClassroomClassroom--Centered (CC) Centered (CC) Intervention ComponentsIntervention Components
Curriculum to promote math and reading Curriculum to promote math and reading achievement achievement -- ““Mastery LearningMastery Learning””
Classroom behavioral components:Classroom behavioral components:Good Behavior GameGood Behavior Game -- to promote positive to promote positive behavior using peer supportsbehavior using peer supportsWeekly class meetingWeekly class meeting –– teachers guide teachers guide students in a 6students in a 6--step problem solving protocol step problem solving protocol to resolve conflicts and develop social to resolve conflicts and develop social competenciescompetencies
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Hypothesized Mechanisms: Hypothesized Mechanisms: Antisocial Behavior & Antisocial Behavior & Substance AbuseSubstance Abuse
Improved parent and teacher behavior Improved parent and teacher behavior management practicesmanagement practicesReductions in early coercive / aggressive Reductions in early coercive / aggressive behaviorbehaviorReduced likelihood of peer, teacher, and Reduced likelihood of peer, teacher, and parent rejectionparent rejectionIncreased likelihood of acquiring Increased likelihood of acquiring ““social social survival skillssurvival skills””Less likely to drift into deviant peer groupsLess likely to drift into deviant peer groups
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Hypothesized Mechanisms: Hypothesized Mechanisms: Anxious / Depressive Anxious / Depressive SymptomsSymptoms
Improved teacher and parent Improved teacher and parent instructional practices provide support for instructional practices provide support for learninglearningImproved achievementImproved achievementImproved perceptions of competence and Improved perceptions of competence and controlcontrolImproved psychological wellImproved psychological well--beingbeing
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DesignDesign
Effectiveness trial Effectiveness trial –– existing teachers and existing teachers and school mental health professionals delivered school mental health professionals delivered interventionsinterventionsCompletely randomized block design:Completely randomized block design:
3 first grade classrooms in 9 urban elementary 3 first grade classrooms in 9 urban elementary schools (primarily Africanschools (primarily African--American)American)Randomly assigned to an intervention or a standard Randomly assigned to an intervention or a standard setting classroomsetting classroomChildren and teachers randomly assigned to Children and teachers randomly assigned to classrooms within each schoolclassrooms within each school
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Assessment design and Assessment design and methodsmethods
Pretest assessment early fall of first Pretest assessment early fall of first gradegrade
Teacher, school mental health professional, Teacher, school mental health professional, parent, peer, and youth reportsparent, peer, and youth reports
PostPost--test late spring of first gradetest late spring of first gradeAnnual followAnnual follow--up each spring since 1up each spring since 1stst
gradegrade
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Constructs assessed:Constructs assessed:
Proximal targets:Proximal targets:Grades, standardized achievement scores, Grades, standardized achievement scores, attendance, special education, disciplinary removalsattendance, special education, disciplinary removalsAttention / concentration problemsAttention / concentration problemsAggressionAggressionShy / withdrawn behaviorsShy / withdrawn behaviors
Distal targets:Distal targets:Conduct, affective, anxious, substance abuse Conduct, affective, anxious, substance abuse symptoms and disorderssymptoms and disordersGrades, standardized achievement scores, Grades, standardized achievement scores, attendance, special education, disciplinary removalsattendance, special education, disciplinary removals
Ialongo, Werthamer, Brown, Ialongo, Werthamer, Brown, Kellam, & Wang (1999)Kellam, & Wang (1999)
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Proximal Impact Grades 1Proximal Impact Grades 1--22
Improved reading and math achievementImproved reading and math achievementDecreased teacherDecreased teacher--rated total problem rated total problem behaviorsbehaviorsDecreased peerDecreased peer--nominated aggressionnominated aggressionDecreased parentDecreased parent--rated total problem rated total problem behaviorsbehaviorsIncreased psychological wellIncreased psychological well--beingbeing
Highlights of Highlights of Intervention Impact: Intervention Impact:
End of 6End of 6thth GradeGrade
2020
Classroom Centered vs. Control Classroom Centered vs. Control (6(6thth grade boys)grade boys)
0.000.010.020.030.040.050.060.070.080.090.10
Conduct Disorder
ControlClassroom Centered
Odds Ratio: 0.42, 95% CI (0.18-0.98)
P r o
b a
b I
l I t
y o
f E
v e
n t
*
2121
Classroom Centered vs. Control Classroom Centered vs. Control (6(6thth grade)grade)
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
Suspension
ControlClassroom Centered
*
P r o
b a
b I
l I t
y o
f E
v e
n t
Odds Ratio: 0.73, 95% CI (0.56-0.95)
2222
Classroom Centered vs. Control Classroom Centered vs. Control (6(6thth grade)grade)
0.00
0.05
0.10
0.15
0.20
0.25
Parent Report: Child Receive MentalHealth Service
ControlClassroom Centered
*
P r o
b a
b I
l I t
y o
f E
v e
n t
Odds Ratio: 0.53, 95% CI (0.38-0.76)
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Classroom Centered vs. Control Classroom Centered vs. Control (6(6thth grade)grade)
0.000.050.100.150.200.250.300.350.40
School Mental Health ProfessionalReport: Child Receive Mental Health
Service
ControlClassroom Centered
*
P r o
b a
b I
l I t
y o
f E
v e
n t
Odds Ratio: 0.56, 95% CI (0.32-0.99)
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Classroom Centered vs. Control Classroom Centered vs. Control (6(6thth grade)grade)
0.00
0.05
0.10
0.15
0.20
0.25
Teacher Report: Child Needs MentalHealth Service
ControlClassroom Centered
*
P r o
b a
b I
l I t
y o
f E
v e
n t
Odds Ratio: 0.37, 95% CI (0.20-0.70)
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Family Family –– School Partnership vs. Control School Partnership vs. Control (6(6thth grade)grade)
0.000.010.020.030.040.050.060.070.080.09
Conduct Disorder
Control
Family-SchoolPartnership
P r o
b a
b I
l I t
y o
f E
v e
n t
Odds Ratio: 0.69, 95% CI (0.32-1.49)
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Family Family –– School Partnership vs. Control School Partnership vs. Control (6(6thth grade)grade)
0.00
0.05
0.10
0.15
0.20
0.25
0.30
Suspension
Control
Family-SchoolPartnership
*
P r o
b a
b I
l I t
y o
f E
v e
n t
Odds Ratio: 0.59, 95% CI (0.35-0.97)
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Family Family –– School Partnership vs. Control School Partnership vs. Control (6(6thth grade)grade)
0.000.020.040.060.080.100.120.140.160.180.20
Parent Report: Child Receive MentalHealth Service
Control
Family-SchoolPartnership
P r o
b a
b I
l I t
y o
f E
v e
n t
Odds Ratio: 0.66, 95% CI (0.32-0.1.32)
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Family Family –– School Partnership vs. Control School Partnership vs. Control (6(6thth grade)grade)
0.000.050.100.150.200.250.300.35
School Mental Health ProfessionalReport: Child Receive Mental Health
Service
Control
Family-SchoolPartnership
P r o
b a
b I
l I t
y o
f E
v e
n t
Odds Ratio: 0.66, 95% CI (0.32-1.33)
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Family Family –– School Partnership vs. Control School Partnership vs. Control (6(6thth grade)grade)
0.00
0.05
0.10
0.15
0.20
0.25
Teacher Report: Child Needs MentalHealth Service
Control
Family-SchoolPartnership
P r o
b a
b I
l I t
y o
f E
v e
n t
Odds Ratio: 0.72, 95% CI (0.47-1.11)
Storr, Ialongo, Kellam, & Anthony Storr, Ialongo, Kellam, & Anthony (2002)(2002)
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14131211109876
Intervention StatusControlClassroom CenteredFamily-School Partnership
Kaplan-Meier Estimates of Impact of Interventions on Youth Tobacco Smoking
AGE
40
30
20
10
0P e
r c e
n t
S t
a r t
I n
g T
o b
a c
c o
U s
e
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Classroom Centered vs. Control Classroom Centered vs. Control (11(11thth grade)grade)
0.00
0.01
0.02
0.03
0.04
0.05
0.06
0.07
Experimentation with Illicit/Hard Drugs
ControlClassroom Centered
Odds Ratio: 0.30, 95% CI (0.12-0.78)
P r o
b a
b I
l I t
y o
f E
v e
n t
*
3333
Classroom Centered vs. Control Classroom Centered vs. Control (11(11thth grade boys only)grade boys only)
0.00
0.01
0.02
0.03
0.04
0.05
0.06
0.07
0.08
Conduct Disorder: Youth Report (boys)
ControlClassroom Centered
Odds Ratio: 0.48, 95% CI (0.20-1.17), p < .10
P r o
b a
b I
l I t
y o
f E
v e
n t
+
3434
Classroom Centered vs. Control Classroom Centered vs. Control (11(11thth grade)grade)
0.00
0.05
0.10
0.15
0.20
0.25
0.30
School Suspension in Last Year
ControlClassroom Centered
Odds Ratio: 0.40, 95% CI (023.-0.70)
P r o
b a
b I
l I t
y o
f E
v e
n t
*
3535
Classroom Centered vs. Control Classroom Centered vs. Control (11(11thth grade)grade)
0.00
0.05
0.10
0.15
0.20
0.25
0.30
Teacher Report: Youth ReceivedCounseling for Behavior Problems
ControlClassroom Centered
Odds Ratio: 0.39, 95% CI (0.20-0.74)
P r o
b a
b I
l I t
y o
f E
v e
n t
*
3636
Classroom Centered vs. Control Classroom Centered vs. Control (11(11thth grade)grade)
0.000.020.040.060.080.100.120.140.160.18
Received Special Education
ControlClassroom Centered
Odds Ratio: 0.47, 95% CI (0.24-0.93)
P r o
b a
b I
l I t
y o
f E
v e
n t
*
3737
Classroom Centered vs. Control Classroom Centered vs. Control (11(11thth grade)grade)
0.00
0.05
0.10
0.15
0.20
0.25
Teacher Report: Youth Needs SpecialEducation
ControlClassroom Centered
Odds Ratio: 0.57, 95% CI (0.34-0.96)
P r o
b a
b I
l I t
y o
f E
v e
n t
*
3838
Preliminary ConclusionsPreliminary Conclusions
Evidence of distal impacts of firstEvidence of distal impacts of first--grade grade universal interventions (10 years later)universal interventions (10 years later)Effects for school and externalizing outcomes Effects for school and externalizing outcomes but not internalizing outcomesbut not internalizing outcomesEffects of CC interventions stronger and longer Effects of CC interventions stronger and longer lasting than FSP effectslasting than FSP effects
CC = Teachers received 60 hours training / CC = Teachers received 60 hours training / supervisionsupervisionFSP = Parents received nine 90FSP = Parents received nine 90--minute sessions; minute sessions; children wellchildren well--behavedbehaved
Impact seems to be greatest for youth at Impact seems to be greatest for youth at moderate riskmoderate risk
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Future Directions for Future Directions for Understanding Distal ImpactUnderstanding Distal Impact
Moderator analyses Moderator analyses –– for whom, to what for whom, to what degree, for how long and in what contexts are degree, for how long and in what contexts are interventions most effectiveinterventions most effectiveMediationalMediational analyses to examine hypothesized analyses to examine hypothesized mechanismsmechanismsUse of growth modeling methods to examine Use of growth modeling methods to examine change in change in trajectoriestrajectories over timeover time
Growth mixture methods to examine differential Growth mixture methods to examine differential intervention effects for different trajectoriesintervention effects for different trajectories
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Future Directions for Future Directions for Prevention TrialsPrevention Trials
Combinations of CC and FSP Combinations of CC and FSP interventions may lead to additive if not interventions may lead to additive if not synergistic effectssynergistic effectsIntegration of selected and indicated Integration of selected and indicated interventions within universalsinterventions within universalsVisit Visit http://www.bpp.jhu.eduhttp://www.bpp.jhu.edu for slides for slides and more information regarding new and more information regarding new PIRC trialsPIRC trials