Lucilla Strada

Università degli Studi di Pavia

Dipartimento di Chimica

lucilla.strada @unipv.it

UNIVERSITÀ DEGLI STUDI DI PAVIA

Dipartimento di Chimica

Contenents

Chemical risk

CLP, new classification

CMR

DPC – safety hoods

Risk

Hazard

Exposure

Exposure assessment

Routes of exposure

Likelihood & extent of exposure

Hazard identification (acute, chronic)

Local/ systemic effects

Dose response characterisation

Uncertainty factors

Margins of safety

Chemical Risk

Chemical Risk

- explosions, fires

- accidental contacts

Hygienic-environmental risks:

- High or extended exposure to harmful/toxic

substances

Accidental risks:

If safety risk assessment

demonstrate that…

… risk for safety is not

LOW and NOT irrelevant

for health …

Health

surveillance

Specific measures for prevention

and protection

Emergency

measures and

monitoring

Risk evaluation…

1) Know the danger

2) Know the systems to protect from danger

3) Create simple safety procedures

LIMIT DAMAGES TO HEALTH AND

RISKS OF ACCIDENTS

Dangerous

Chemical Agents Substances and Preparations that are Classified

or Classifiable as dangerous

Leg. Decree 52/97 s.m.i. Directive 67/541/CEE

Leg. Decree 65/03 s.m.i.

Toxic gases

R.D. 09/01/27 n. 147 Substances used under specific conditions

eg. cryogenic liquids

inert gas

http://www.dors.it/matline/help.php

Since december, 1 2010 classification, labelling and

packaging of chemical is under a new regulation ((CE) n.

1272/2008) that modifies the old CEE directives.

DSP

• 67/548/CEE

• Abrogated since 1/6/2015

DPP

• 1999/45/CE

• Abrogated since 1/6/2015

REACH

• CE 1907/2006

• Modified by CLP

– transposition of GHS ONU: Global Harmonization System of Classification and Labelling of Chemicals

Labelling evolution

Labelling evolution

Labelling evolution

AVVERTENZA Pericolo Pericolo Pericolo attenzione attenzione

letale letale letale nocivo Può essere nocivo

Nessun

pittogramma

CLP Categoria 1 Categoria 2 Categoria 3 Categoria 4 Categoria 5

DSP

Molto tossico T+

R28

Tossico

R25

Nocivo Xn

R22

DL 50 mg/Kg 5 25 50 200 300 2000

5000

CMR risk

EXPOSURE ASSESSMENT

As for chemical risk assessment

DETERMINISTIC EFFECTS

Damages whose frequency and severity vary with dose so that a

treshold dose is detectable.

The Manifestations of gravity increases with increasing dose

STOCHASTIC EFFECTS

Only the probability of occurrence, not the severity depends on the

dose and is conservatively excluded the existence of a threshold

dose

There is no gradation of the event with the dose received, whatever

the dose

Carcinogenic

• Cat. 1A: Known to have carcinogenic potential for humans

• Cat. 1B: Presumed to have carcinogenic potential for humans

• Cat. 2: Suspected human carcinogen

Mutagenic

• Cat. 1A: Substance known to induce heritable mutations in the

germ cells of humans

• Cat. 1B: Substance to be regarded as if it induces heritable

mutations in the germ cells of humans

• Cat. 2: Substance which causes concern for humans owing to

the possibility that it may induce heritable mutations in

the germ cells of humans

Reproductive toxicants

• Cat. 1A: Known human reproductive toxicant

• Cat. 1B: Presumed human reproductive toxicant

• Cat. 2: Suspected human reproductive toxicant

CMR classification [Regulation N° 1272/2008]

Safety hoods must be:

according to law

suitable for the type of danger and risk level estimated

installed correctly

Correctly used

Putted under maintenance

their efficiency verified

Safety Hoods

Reference

legislations

ITALIAN LEGISLATION SUCTION HOODS

UNI EN 14175

PART 1:

vocabulary

PART 2:

Safety standard and performance

PART 3:

Methods for homologation testing

PART 4:

Methods for on-site testing

PART 5:

Recommendations for installation and maintenance

PART 6:

Suction hoods at variable air volume

14175

PART 2: Safety and Performance Standards

14175-2

- Dimensions

- Essential goals for safety and performance

- Materials

- General safety standards

- Airflow

- Services

- Product Manual

- Brand and labeling/tagging

- Conformity evaluation

PART 3: Methods for homologation testing

14175-3

- Lab and general conditions testing

- Air range testing

- Latch testing

- Range marker testing

- Building and materials testing

- Lighting testing

- Testing report

- Noise testing

PART 4: On site testing methods

14175-4

- Conditions of on-site testing

- Commissioning test for certified hoods

- Routine testing for certified hoods

- Qualification testing for non-certified hoods

- Routine testing for qualified hoods

- Testing Final report

PART 5: Recommendations for installation and maintenance

14175-5

- Setting of chemical hood

- Maintenance of chemical hood

PART 6: Suction hoods at variable air volume

14175-6

- Homologation testing methods

- On-site testing methods

- Product Manual

- Brand and labeling/tagging

- Testing final report

Commissioning & qualification, identify a list of tests to be done on the hoods

Tests are described in Part 3: homologation testing methods

Testing hoods performance, is the capacity of the hood to protect the

operator/worker.

Commissioning

& qualification

Air Flow tests

5,1 Extract volume flow rate

5,2 Face velocity

5,3 Containment

5,4 Robustness of containment

5,5 Air exchange efficiency

5,6 Pressure drop

Containment represents the capacity of the hood to keep inside the product

used

Containment = performance

Containment

Containment tests consist in:

INNER PLANE

OUTER PLANE

ROBUSTNESS

Inner plane

The red spots placed inside the hood represent the points of emission of the tracing gas.

The green spots represent the sampling points _9

The samples are taken out to the hood frontal

The test is repeated n times depending on the size of the hood

Tests are repeated on 2 levels, a low and a high one

Outer plane

9 tracing gas emission points are placed inside the hood

The sample is taken out to the whole surface of the hood frontal, while the sampler is

placed outside of the hood frontal

Robustness

Tracing gas emission points and the sampler are placed

in the same configuration as in the OUTER PLANE

The test consists in voluntarily creating a disturb, when a

Panel is put in front of the hood

The panel simulates the passage of a person