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    Better Living Through Nanotechnology:Unique applications of magnetic composites

    Thompson Mefford

    Materials Science and Engineering

    [email protected]

    Meffordresearch.com

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    MRI Contrast Agents(Relaxometry): Multi Mode Imaging(MRI + Optical/PET/CT/SPECT):

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    Magnetic Hyperthermia or MagMED:

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    Examples of Magnetic Directed Self Assembly forStructured Composite Materials

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    "GI]8: #A\AMI7IOI:>

    Polymer

    Nanoparticle

    Surface Ligand

    AdditionalFunctionality

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    Polymer

    Nanoparticle

    Surface Ligand

    Additional

    Functionality

    A wide variety of metal and metal oxide nanomaterialsare synthesized by the Me!ord Lab.

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    Polymer

    Nanoparticle

    Surface Ligand

    Additional

    Functionality

    Custom synthesis of heterobifunctional polymers provides a

    framework for being able to approach multiple applications with a

    central core material

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    Polymer

    Nanoparticle

    Surface Ligand

    Additional

    Functionality

    By controlling the end group chemistry through click or othermethods particles can be tuned to specific applications

    O

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    N3

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    HO

    OH

    OH

    OH

    HO

    HO

    HNAc

    OH

    HO

    NHAc

    OH

    HO

    HO

    CO2Na

    +

    Ground state depletion image of Cy5

    labeled in a Legionella biofilm

    Schematic of functionalization of ironoxide particles with triglycerides for the

    disease specific targeting of bacteria

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    Our Needs:

    What We Can Offer:

    Industrial partners for: Internships for students Shared research objectives (sponsorship, NSF SNM,

    GOALI, etc.) Understanding industrial needs

    Unique synthetic capabilities(catalysts, processes, and equipment)

    Synthetic challenges for new material development

    Workforce development Directed assembly of polymer nanocomposites New avenues of nanomanufacturing Unique nanomaterial structures Robust surface modifications Custom heterobifunctional polymers Instrumentation and expertise for the measurement and

    characterization of colloids and nanostructured materials

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    &Y^G6J7:KB9:GO>National Science Foundation (DMR-0907167,CMMI-1057633, CMMI-1130819, CBET-1236041)

    Thompson Mefford

    Materials Science and Engineering

    [email protected]

    Meffordresearch.com