Providing Flexible Resourcing Solutions CTC Resourcing Solutions, founded 1997, is a pan-European specialist staffing organisation with offices in London, Basel and Munich, providing flexible resourcing solutions to the pharmaceutical industry across Europe, with contract and permanent placements in clinical development, data management, statistics, regulatory affairs and medical marketing For a key client, we are currently looking for a:

Pre-Clinical Development Scientist Reference Number: 893175-W Type of placement: Permanent Location: Home counties, UK Our client is a drug discovery and development company focused on the development of two innovative high-value clinical-stage programmes that target diseases of significant unmet medical needs specifically neuromuscular disease and infectious disease. With the objective of developing best-in-class drugs, activities are continuing in parallel with the advancement of the company’s lead compound which is expected to enter clinical trials in patients during Q4 2013. In order to ensure achieve this, our client now requires a Pre-clinical development Scientist who will plan and direct pre-clinical programmes with the objective of identifying viable candidates for further development. The Pre-clinical Development Scientist will be responsible for supporting the pre-clinical development strategy including the planning, conduct, interpretation and reporting of ADME studies for the neuromuscular programme. You will enjoy a high level of autonomy and independence working closely with the leadership team to guide and shape the pre-clinical development strategy. As well as providing direction to CROs and other vendors you will be hands-on in all aspects of pre-clinical research including, expediting next generation molecules from lead optimization to preclinical drug development and Phase 1 healthy volunteer trials. In summary, this is an outstanding and unique opportunity for an experienced professional with a range of skills and expertise in molecular biology, safety pharmacology and ADME and to take a leading role within an innovative and exciting drug development company. You will have a high profile role within the organisation and will work in partnership with the executive leadership of an organisation that is highly committed to the development of novel DMD drug candidates. Main Responsibilities:

Provide leadership and direct the development of in vivo data packages to advance next generation molecules to Investigational New Drug Application (IND)

Oversee the conduct of in vivo studies in support of the DMD programme

Design and conduct DMPK, ADME and Toxicology studies to be performed externally

Establish collaborations with outside academic and industry experts

Manage outside projects with CROs

Accountability for project success and results delivery

Receive, process and interpret external data to facilitate decision making by the project teams

Interact closely with discovery research and clinical development and manufacturing

Follow relevant SOPs and quality processes required for GLP studies

Manage budget and resource allocation

Communicate research development findings internally and externally as appropriate

Qualifications and Experience:

PhD with 5+ years hands-on experience in conducting ADME studies required

Ability to manage and maintain scientific business relationships and contract research agreements

Excellent technical understanding

Ideally a generalist with molecular biology and pharmacology in the skill set

Desire to approach a range of topics including; target validation, molecular mode of action, and safety pharmacology

Desire to expand into other areas of pre-clinical development including in vivo pharmacology and toxicology

Excellent technical understanding

Strong written and oral communication skills

Positive teamwork skills

Should you be interested in the above position and wish to apply, please send your application with your CV, quoting the above reference number, to our recruitment team at recruitment@ctcon.ch

CTC Resourcing Solutions, 117 Waterloo Road, SE1 8UL, London, UK

Tel.: +44 207 193 9972 www.ctcresourcing.com info@ctcon.ch