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Wei-Chih Wang University of Washington Micro Technology Laboratory Polymer Based Micro sensors and actuators in Biomedical Applications

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Page 1: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Wei-Chih WangUniversity of Washington

Micro TechnologyLaboratory

Polymer Based Micro sensors andactuators in Biomedical Applications

Page 2: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Our Goal

Integration of current MEMS and photonicstechnology in biomedical applications

Page 3: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

• Federal estimates predict that health care spending will

surpass the $2 trillion mark in the next decade. Within the health care technology, biomedical device is one of the fastest growing segments

• Advance in sensor and transducer technologyallows:

- Mass production (lower cost, high throughput,disposable)

- Miniaturization (increase sensitivity, portability,new diagnostics tools)

Why Biomedical Application?

Page 4: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

PhD Students Master Students Undergraduates

Joe Ho, ME Reynold Panergo, ME Steve Evans PhysicsChen-Shen Huang, ME Jiang Shiao, ME Jeff Dee, Chem EChu-Yu Huang, ME Benjamin Estroff , EEMichael P. Weller, Architecture Raymond Chung, pre-engr

James Etzcorn, pre-engrHamed Khoojinian, pre-engrAimi Ahmad-Shukri, pre-engrAnna Leung, pre-engr

Staff

Christopher Galvanin, graphic designDaniel Ortiz, PhysicsChristopher lee , PhysicsAbram Clark

University of WashingtonMicro Technology Laboratory

Page 5: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

• PNETAX CO.• University of Washington Human interface laboratory• Cyma Corp.• RR&D Center of Excellence for Limb Loss Prevention and Prosthetic Engineering

at the VA Puget Sound Health Care System in Seattle• UW medical school• University of Washington Material Science Organic Functional Polymers

Laboratory• UW mechanical Engineering Vibration and Dyunamic Labortory• University of Washington Media Center (architecture department)• Carnegie Mellon University• National Central University• National ChengKong University• National Huwei University of Science and Technology• Southern Taiwan University of Technology

Collaborators

Page 6: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Self-Configurable Modular Robot

self-configuringbuilding block toexplore thepotential uses ofdynamic structures

W.-C. WangSelf-Configurable Modular Robot

Page 7: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Espresso stand during theday and living quarter at night

Dynamic Structures

W.-C. WangSelf-Configurable Modular Robot

Page 8: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Block constructed using RapidPrototype Technique

W.-C. WangSelf-Configurable Modular Robot

Page 9: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Pallet to Wall Action

W.-C. WangSelf-Configurable Modular Robot

Page 10: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Wall to Window

W.-C. WangSelf-Configurable Modular Robot

Page 11: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

MICROMACHINED ACOUSTIC-WAVELIQUID EJECTOR

W.-C. WangMicromachined Acoustic-Wave Liquid Ejector

Page 12: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Liquid Ejector

SurfaceTension

AcousticWave

Liquid/AirInterface

Beam Diameterat Focal Plane

Rising LiquidCylinder

Droplet Formation due to Focused Acoustic Wave

Droplet Diameter ~ Beam Diameter at Focal Plane

Function of Radiation Pressure & Surface Tension

D

Radiation Pressure (2If/Va)

W.-C. WangMicromachined Acoustic-Wave Liquid Ejector

Page 13: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Fabricated Device

(Micromachined Lensless Liquid Ejector)

Transducer SpecificationsRF Frequency: 300 MHzZnO Thickness: 10.55 µmFocal Length: 400 µm

Half-Wave-Band Sources: 7Predicted Droplet Diameter: 5 µm

100 µm

W.-C. WangMicromachined Acoustic-Wave Liquid Ejector

Page 14: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

80 µm 60 µm

30 µm 15 µm

Time evolution of the liquid ejection process produced by our600MHz SFAT with an RF pulsewidth of 30µsec

W.-C. WangMicromachined Acoustic-Wave Liquid Ejector

Page 15: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

MEMS acoustic sensor-hotwire sensor(thermo-resistor)

temperature

resistance Temp.

Flow rate

W.-C. WangViscosity and Mass Flow Sensors

Page 16: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Viscosity and Mass Flow Sensors

W.-C. WangViscosity and Mass Flow Sensors

Entrain mass

Cf from liquid

Liquid

Fiber

Transducer

from liquid or

z

x

Tensile force

Tensile force

Fx

F x

:

:

:

:

:

or air

air

Caρ

l A

m

= mentrained

A Linear, Single Degree of Freedom System with Viscous Damping Model

(m+mentrained)x+ (Cs+Cf)x + kx = f(t)

Page 17: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Viscosity Measurement

Frequency (Hz)

Max

imum

disp

lac e

me n

t(d

b)

5% Sucrose10%Sucrose20%Sucrose30%Sucrose40%Sucrose

airwater

x

x

ExperimentSimulation

1/sqrt(ρµρµρµρµ)ρµ)

x

x

x

x

Max

imum

disp

lac e

me n

t(d

b)

W.-C. WangViscosity and Mass Flow Sensors

Regime of unseparated flow Xmax� 1/(ρµ)0.5

Page 18: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

For small flow rate, Re< 30, experimental result show

1/xmax V1.27

Reynold’s numberFlow velocity (m/s)

1/x m

ax(1

/mV

)

1/x m

ax(1

/mV

)

W.-C. WangViscosity and Mass Flow Sensors

Xmax� 1/ρVMass Flow Measurement

Page 19: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Max

imum

disp

lac e

me n

t(d

b)

Frequency (Hz)

Different Submerged Depth

Frequency (Hz)

Max

imum

disp

lac e

me n

t(d

b)

Experimental result Simulation result from FEM model

W.-C. WangViscosity and Mass Flow Sensors

Page 20: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

• Vertical plantar pressure has been associated withthe development of ulcers

• Others have postulated shear stress is animportant component of ulcer development

- little known about actual distribution- lack of validated commercially available

shear sensor

Foot Ulcers Caused by Mechanical Trauma

W.-C. WangPolymer based Pressure/Shear Sensor

Page 21: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Developing a distributive optical sensor capable of :• Simultaneously measuring vertical and horizontal

loads• Detecting the direction and the magnitude of the

loads• Creating a linear relationship between signal and

applied load and without hysteresis.• Leading to a multi-channel distributive

pressure/shear sensor• High spatial resolution

Project Objectives

W.-C. WangPolymer based Pressure/Shear Sensor

Page 22: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Polymer based Pressure/Shear Sensor

LED

WaveguideSensor

PhotodetectorArray

DataAcquisition

System

•Higher spatial resolution (250µm x 250µm)

W.-C. WangPolymer based Pressure/Shear Sensor

Page 23: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications
Page 24: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

NormalFoot

Flat Foot

*Medialdeviation ofCOP withoutthe arch

*High pressure(0.82 MPa) underthe secondmetatarsal head

Compare Normal & Flat Foot PlantarPressure Distribution

W.-C. WangPolymer based Pressure/Shear Sensor

Page 25: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Optical Scanner:Image Acquisition and Display

SU-8 Cantilever Waveguide

Waveguide withX-Y Bimorph Transducers

Background:• Single cantilever beam actuated in both X

and Y direction to provide raster scanning ofimages

• Function as image display with controlledpulse LED

Current Design:• Microfabricated SU-8 Waveguide with

50x100 µm cross section• Mounted on X-Y bimorph transducers• 2-D Image Acquisition is achievable

Application:• Alternative to current endoscopic devices

which use bundle of optical fibers• Portable image display device

W.-C. WangIntegrated optical scanner for Image acquisition/display

Page 26: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Optical Scanner:MEMS Based Device

2-D Comb Drive Actuator

What needs to be achieved?• An integrated system of light source,

waveguide, actuators, control feedbackare desired as the overall designimplementation for the optical scanner.

Integrated MEMS Actuator:• The design and fabrication of a MEMS

actuator will be the next step in theprocess

• The device will integrate comb drivesas a means of actuation

• Microfabrication of the actuators willutilize a Bosch DRIE Process and WetChemical Release Etch

W.-C. WangIntegrated optical scanner for Image acquisition/display

Page 27: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

4.2

4.3

4.4

4.5

4.6

4.7

4.8

1 201 401 601 801 1001 1201 1401

2D Scan on ‘3 Bar’ Black Shape with Transparent Background

150umTop Figure:3 Bar with Transparent Background*square mesh is scanning area

Bottom Figure:Intensity vs. Number of Scans

Sampling Rate: 100000 scans/secHorizontal Frequency: 25HzHorizontal Amplitude: 600mVVertical Frequency: 4.710kHzVertical Amplitude: 600mV

W.-C. WangIntegrated optical scanner for Image acquisition/display

Page 28: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Display image using pulse modulation on input light source

Modulating frequencies on LED

Horizontal =38.48 kHz

Vertical =190.6 Hz

W.-C. WangIntegrated optical scanner for Image acquisition/display

Page 29: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

+-

Dielectric Elastomer Actuator

� Electrodes on top and bottom

� High voltage is passed through the electrodes

� Positive and negative charges build up on the top andbottom acting as a capacitor

-+

� Once a high enough voltage is reached, the electrodesare forced together squeezing the elastomer

� Under the resulting stress, the elastomer stretches

W.-C. WangDielectric Elastomer Actuator

Page 30: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Demonstration

W.-C. WangDielectric Elastomer Actuator

Page 31: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

• No energy input required• Can levitate at room temperature• Potential applications:- Frictionless motor or generator-

Diamagnetic Levitation

Levitated magnets

W.-C. WangDiamagnetic Levitation

Page 32: Polymer Based Micro sensors and actuators in Biomedical ...depts.washington.edu/mictech/home/links/xxx.pdf · Polymer Based Micro sensors and actuators in Biomedical Applications

Wei-Chih WangResearch Assistant ProfessorDepartment of Mechanical EngineeringUniversity of WashingtonSeattle, WA. 98195-2600Phone: 206-543-2479E-mail: [email protected]: faculty.washington.edu/abong

Contact Information