1

PET•CT cardiac perfusion and viability mismatch study

Stress

13NH3 Perfusion

18FDG Viability

Perfusion-viability mismatch in 13N-NH3 PET perfusion and 18F-FDG PET viability study

Mismatch indicative of ischemic but viable myocardium - capable of return to normal

contractility with revascularization

Patient identified as a candidate for revascularization.

Source: Data Courtesy of University of Michigan

Rest

13NH3 Perfusion

18FDG Viability

2

Cardiac PET Evaluation of Myocardial Perfusion and Metabolism

Source: Data Courtesy of Cleveland Clinic Foundation, Cleveland OH, Dr. Neuman

NH3

FDG

NH3

FDG

NH3

FDG

RestingPerfusion

Viability

RestingPerfusion

Viability

RestingPerfusion

Viability

3

82Rb Cardiac PET/CT

Source: Data Courtesy of Medical Imaging Center, Grand Rapids, MI, USA, Dr. P. Shreve

33 year old male, 79.5 kg (175 lbs.)Cardiac Stress, Rest and Gated PET slices.

16 Gate 82Rb Cardiac PET/CT

Data Courtesy of Cleveland Clinic Foundation, Cleveland, OH

Stress

Rest

Gated

16

Stress

Rest

Gated

Stress

Rest

Gated

Stress

Rest

Gated

4

Cardiac 82Rb PET

Source: Data Courtesy of Cleveland Clinic Foundation, Cleveland OH, Dr. Neuman

Stress

Rest

Stress

Rest

Stress

Rest

Normal Myocardial Perfusion Static Stress and Rest Test

5

47 year old patient with non-specific chest pain presented for evaluation to rule out coronary artery disease.

A PET•CT rest perfusion study was performed with Rb, along with a CT angiography of the coronary vessels.

Source: Images courtesy of Emory Crawford Long Hospital, Atlanta, GA, Dr. Patterson

Cardiac – Rule out Coronary Artery Disease