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Perioperative Management Of Extra-Ventricular Drains (EVD) Dr. Vijay Tarnal MBBS, FRCA Clinical Assistant Professor Division of Neuroanesthesiology Division of Head & Neck Anesthesiology Michigan Medicine

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Page 1: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Perioperative Management

Of Extra-Ventricular Drains

(EVD)

Dr. Vijay Tarnal MBBS, FRCA

Clinical Assistant Professor

Division of Neuroanesthesiology

Division of Head & Neck Anesthesiology

Michigan Medicine

Page 2: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Disclosures

• None

Page 3: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Outline• To understand the common indications &

complications with extra-ventricular drain

(EVD) placement

• Pre-operative assessment of patients

presenting with EVD

• To suggest management of patients with

EVD in the perioperative setting including

monitoring and CSF drainage

Page 4: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Introduction

• Temporary devices placed to facilitate external

CSF drainage and to monitor ICP

• Between 1988-2010 around 500,000

ventriculostomies placed1

• Majority in SAH, ICH or Obstructive

Hydrocephalus1

• Encountered in OR setting by clinicians with

limited experience

• Mismanagement can be catastrophic

1 Rosenbaum et al; J Clin Neurosci. 2014

Page 5: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Rosebaum et al; J Clin Neuroscience 2014

Page 6: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Rosebaum et al; J Clin Neuroscience 2014

Page 7: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

History of EVD Placement

• 4 eras of progress1:

Development of technique (1850-1908)

Technological Advancements (1927-1950)

Expansion of Indications (1960-1995)

Accuracy, Training, Infection control (1995-

Present )

1 Srinivasan et al; J Neurosurg 2014

Page 8: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

1 Srinivasan et al; J Neurosurg 2014

Page 9: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

EVD Materials

1 Srinivasan et al; J Neurosurg 2014

Page 10: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Freeman, W.D. (2015). Neurocritical Care, 1299-323.

ICP Monitoring

Page 11: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Outline• To understand the common indications &

complications with extra-ventricular drain

(EVD) placement

• Pre-operative assessment of patients

presenting for or with EVD

• To suggest management of patients with

EVD in the perioperative setting including

monitoring and CSF drainage

Page 12: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

EVD Placement Indications

Page 13: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

1. Acute Symptomatic Hydrocephalus

Aneurysmal SAH

ICH and IVH with decreased level of

consciousness

Acute ischemic cerebellar stroke in concurrence

with decompressive craniectomy

1 Lele et al; J Neurosurg Anesthesiol 2017

Indications for Placement of EVD

Page 14: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Indications for Placement of EVD

2. ICP monitoring in TBI

TBI with post resuscitation GCS of 3-8 and

abnormal CT

Severe TBI with a normal CT scan if >2 of features

present (age>40, motor posturing or SBP<90)

Management of Intracranial Hypertension after

TBI

1 Lele et al; J Neurosurg Anesthesiol 2017

Page 15: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

3. Malfunctioning or infected V-P Shunts

4. Facilitation of intraoperative brain

relaxation

5. Targeted Therapeutic Interventions rTPA in patients with IVH and SAH?

Treatment of vasospasm after SAH

Antibiotics in management of CNS infections

Indications for Placement of EVD

1 Lele et al; J Neurosurg Anesthesiol 2017

Page 16: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Indications for placement of EVD

Page 17: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Site for EVD Placement

• Placed either electively in OR/IR or

emergently at bedside1,2

• Frontal horn of right lateral ventricle-

Preferred Destination

• Non-Dominant side for speech &

language for most patients

1 Foreman et al; Clin Neurol Neurosurg. 20152 Kakarla et al; Neurosurgery 2008

Page 18: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

≅28mm

≅101mm

mean intracranial catheter

length was 60 mm

Abdoh et al; Acta Neurochir 2012

Page 19: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Complications Associated with EVD

Placement1,2,3

1. HemorrhageIntracerebral hemorrhage, tract hematoma or tract

hemorrhages (0-41%)

2. Infection (0-28% EVD)

3. Malposition

4. Occlusion and malfunction

1 Lele et al; J Neurosurg Anesthesiol 20172 Miller C: J Neurosurg. 20173 Niiumara et al; BMJ Case Rep. 2015

Page 20: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Complications Associated with EVD

Placement1,2,3

5. Over Drainage of CSF Subdural or epidural hematoma

Re-bleed from a ruptured cerebral aneurysm

Intracranial hypotension

Cerebellar tonsillar herniation

Paradoxical herniation

Pneumocephalus

1 Lele et al; J Neurosurg Anesthesiol 20172 Miller C: J Neurosurg. 20173 Niiumara et al; BMJ Case Rep. 2015

Page 21: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Complications Associated with EVD

Placement1,2,3

6. Iatrogenic vascular injury (arteriovenous

fistula, cerebral pseudo aneurysm)

7. Fracture of catheters, with retained

fragment of catheters

8. Inadvertent injections of drugs

1 Lele et al; J Neurosurg Anesthesiol 20172 Miller C: J Neurosurg. 20173 Niiumara et al; BMJ Case Rep. 2015

Page 22: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Complications with EVD Placement

Page 23: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

EVD System

Page 24: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

EVD System

Page 25: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

EVD System

Page 26: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

EVD System

Page 27: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

EVD Setup

Page 28: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

EVD Setup

Page 29: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

EVD Setup

Page 30: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Do not connect EVD system to a high pressure

system such as pressure bag used for arterial or

central venous catheter

Page 31: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Why Do We Need Guidelines?

Page 32: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

• 51% of transports resulted in secondary

insults

• Commonest were Arterial Hypertension &

Intracranial Hypertension

Page 33: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Outline• To understand the common indications &

complications with extra-ventricular drain

(EVD) placement

• Pre-operative assessment of patients

presenting for or with EVD

• To suggest management of patients with

EVD in the perioperative setting including

monitoring and CSF drainage

Page 34: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Pre-Operative Evaluation

• Inspection of EVD System

• Understanding Drain Dynamics

• ICP Waveforms

• Results of Clamp Trial

Page 35: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Understanding Drain Dynamics

• CSF drainage under controlled settings

• CSF drain volume goals <10-20ml/hr

• Setting of EVD depends on indication for its

placement

• Aneurysmal SAH (typical EVD settings)1,2

Pre Repair. : +20cm H2O

Post Repair : +10cm H2O

1 Sakowitz et al; Neurosurg 20062 Chung et al; Neurocrit Care 2017

Page 36: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and
Page 37: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

ICP Waveforms

Lele et al; J Neurosurg Anesthesiol 2017

Page 38: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Clamping Trials

• Tolerance to any period of clamping

depends on:

1. Indication for EVD placement

2. ICP trends

3. Dependency on external CSF diversion

• At Risk Patients:

External CSF diversion dependency

Elevated ICP

Page 39: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

• 11.8% of patients with post-IHT ICP>20

• 18.5% of patients with escalation of ICP

category

• Risk Factors

• Pre-IHT ICP>20, Therapeutic Procedures.

Page 40: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

SNACC Guidelines Summary1

• Thorough Pre-Op evaluation

• Inspection of EVD system

• ICP values, trends and other multimodal

monitoring data

• Drain Dynamics

• Clamping Trials

• Standard pre-operative handoff between

NICU and Anesthesia providers

1 Lele et al; J Neurosurg Anesthesiol 2017

Page 41: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Outline• To understand the common indications &

complications with extra-ventricular drain

(EVD) placement

• Pre-operative assessment of patients

presenting for or with EVD

• To suggest management of patients with

EVD in the perioperative setting including

monitoring and CSF drainage

Page 42: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Intra-Hospital Transport (IHT)

of Patients with EVD

Page 43: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

• At risk for secondary insult from

intracranial complications

• Change in patient position may lead to

CSF over drainage

Rebleeding of Aneurysm

Subdural Hemorrhage

Paradoxical Brain Herniation

Intra-Hospital Transport (IHT)

of Patients with EVD

Page 44: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

SNACC Guidelines Summary1

1 Lele et al; J Neurosurg Anesthesiol 2017

Page 45: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Intraoperative Management of

EVD

Page 46: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Intraoperative Management of EVD

1 Rosner et al; JNS 19862 Birch et al: Neurocrit Care 20063 Wilkinson et al; Neurosurgery 1986

Page 47: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Management of EVD in Special Scenarios1

• Visual aids and labeling

• Accidentally disconnected EVD tubing should

be clamped immediately

• All distal parts of device replaced with a new

sterile tubing (Not the EVD catheter)

• Routine flushing of catheter should not be

performed

• Notify neurosurgery team immediately if there is

an accidental injection via EVD

Lele et al; JNA 2017

Page 48: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Lele et al; JNA 2017

Checklists

Page 49: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Educational Resources

Page 50: Perioperative Management Of Extra-Ventricular Drains (EVD) · 2019. 2. 21. · Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and

Summary

• Common indications, contraindications

and patient preparation for extra-

ventricular drain (EVD) placement

• Pre-operative assessment & IHT of

patients presenting for or with EVD

• Management of patients with EVD in the

perioperative setting including monitoring

and CSF drainage